Trans-NIH Jak-Stat Initiative - Erythroid: Stat5KO vs WT

Changes in comparison: All samples for Erythroid: Stat5KO vs WT

Erythropoietic Ter119+ cells from mouse fetal liver cells from Stat5-KO and WT mice.. This used mAdb test: EG1-test-1-FC-ALL.

Erythroid: EG001
(T1-)  Stat5KO vs WT --- fold changes < 2X and p-Value<0.05.

This mAdb-derived analysis report compares two groups of samples (A and B) using the paired t-test followed by a fold-change test with the threshold values listed above. The t-test is only done if are at least two samples/condition. It performs fold-change thresholding in either case. The mean A and mean B values are shown as log2 values in the following table as A Mean and B Mean. If there are not enough samples in either condition A or condition B, it only compares the fold-change (mean A/mean B) computed as the difference between the log2 means shown as A-B Mean Difference in this report - see Data Analysis Methods for more discussion. If the t-test is performed, the p-Value is reported as A-B p-Value. Individual sample expression values are reported as the RMA normalized values not using the log2. The tests, thresholding and mAdb Retrieval Report were generated on the mAdb system for the GSP data and subsequently converted to this Web page.

Clicking on the table entries for Gene, Well ID, and Feature ID will go to the GeneCard, mAdb Feature Report, and Affymetrix probe database Web page for that entry. The genes are sorted by A-B Mean Difference with:
   (A) Samples[Stat5KO]: EG001-01, EG001-02, EG001-03
   (B) Samples[WT]: EG001-04, EG001-05, EG001-06.

mAdb Microarray Retrieval Report - All Samples

Preface to table

Row                 A A A A A A B B B B B B C C C C C C  
Row Gene A-B Mean Difference A Mean (Stat5KO) B Mean (WT) A-B p-Value Well ID Feature ID Description EG001-01.Erythroid.Stat5KO.br1.noStim EG001-02.Erythroid.Stat5KO.br2.noStim EG001-03.Erythroid.Stat5KO.br3.noStim EG001-04.Erythroid.WT.br1.noStim EG001-05.Erythroid.WT.br2.noStim EG001-06.Erythroid.WT.br3.noStim EG003.1-01.Muscle.Stat5MKO.42.GH EG003.1-02.Muscle.Stat5MKO.43.GH EG003.1-03.Muscle.WT.44.GH EG003.1-04.Muscle.WT.47.GH EG003.1-05.Muscle.Stat5MKO.48.GH EG003.1-06.Muscle.WT.50.GH EG003.2-01.Muscle.WT.4038WT.noStim EG003.2-02.Muscle.WT.4060WT.noStim EG003.2-03.Muscle.WT.4063WT.noStim EG003.2-04.Muscle.Stat5MKO.4035KO.noStim EG003.2-05.Muscle.Stat5MKO.4036KO.noStim EG003.2-06.Muscle.Stat5MKO.4042KO.noStim Gene Ontology Terms
1 Rsad2 -1.00541 11.49063 12.49605 0.028431841 1337925 1436058_at radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA. 3553.7718 2629.5130 2549.8264 4510.3187 7803.5445 5477.1646 146.8028 150.9946 160.9076 156.5707 156.2630 171.6313 136.9372 169.0003 154.3591 129.0903 137.9691 168.8063
2 Rfk -1.01706 10.22975 11.24681 0.013241846 1327556 1415737_at riboflavin kinase (Rfk), mRNA. 1059.9895 1371.2126 1191.1804 3052.1127 2355.5366 1996.1509 1837.6283 1895.9957 1996.2630 1950.5557 1853.1011 1882.8204 1774.6864 1697.6241 1816.4391 1771.5154 1662.1674 1514.9834
3 4632432E15Rik -1.03215 4.80835 5.84050 0.0042505687 1353617 1432885_at RIKEN cDNA 4632432E15 gene 28.3046 24.6838 31.4849 68.7762 52.9439 51.6702 30.0462 28.0024 23.6206 24.8092 26.9214 26.3588 21.3713 33.9265 36.4868 23.2157 21.5238 23.2433  
4 Rfk -1.03490 10.06125 11.09615 0.020805506 1327927 1416230_at riboflavin kinase (Rfk), mRNA. 1086.4877 1056.3993 1062.5740 2663.5479 2133.3686 1846.2630 1469.5253 1404.2100 1617.0403 1608.4305 1405.6445 1599.8926 1946.0977 1622.6554 1673.0048 1722.1448 1557.8427 1532.3384
5 Socs3 -1.03648 7.14218 8.17866 0.004395647 1328194 1416576_at suppressor of cytokine signaling 3 (Socs3), mRNA. 120.5971 155.6736 150.1349 347.2172 257.0916 272.5061 2725.9996 2806.0964 802.0430 734.4321 2673.9977 702.4433 234.9824 228.5365 290.1378 416.5916 379.8765 532.6616
6 Rsad2 -1.04647 9.58681 10.63328 0.041430984 1331607 1421009_at radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA. 1039.0083 767.2390 570.4251 1238.0962 2215.4173 1460.8151 37.1475 34.5517 40.1225 42.1413 38.1795 42.1493 33.1825 49.1826 37.5186 25.6519 41.2480 35.0651
7   -1.05571 6.81684 7.87255 0.0066383013 1356168 1437087_at Transcribed locus 123.8638 114.2557 101.2511 280.9402 198.3253 231.0111 78.2396 78.4138 87.4889 83.0110 89.4352 93.0758 83.3886 79.5346 88.7867 77.5333 76.9779 74.8556  
8 Trp53bp1 -1.06538 9.29707 10.36245 0.0090267392 1335793 1426957_at transformation related protein 53 binding protein 1 (Trp53bp1), mRNA. 761.2545 526.6445 620.9314 1187.7547 1416.2861 1356.2756 226.0353 267.9336 233.2908 267.1519 256.1629 274.4983 317.3030 284.0210 316.9650 336.3186 360.8279 299.9436
9 Dnaja4 -1.06573 9.86453 10.93026 0.00033938429 1329833 1418591_at DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA. 858.1519 967.6132 975.6519 1989.2497 2014.3242 1854.3332 1268.0774 1314.3871 1554.0479 1543.3245 1246.4468 1547.7413 1201.2075 1116.8961 888.2387 1476.3819 1543.8367 1159.0891
10 Ucp2 -1.06715 9.05346 10.12061 0.017052203 1361995 1444566_at Uncoupling protein 2 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:13955 IMAGE:4205625) 605.6519 591.2656 418.8741 1201.7630 1053.0408 1090.3186 60.0933 54.9991 97.6009 73.3677 65.5116 71.7715 64.8402 74.6924 66.4189 66.4316 56.9612 64.2739
11 Atad4 -1.07729 6.28994 7.36723 0.01279511 1354336 1433870_at ATPase family, AAA domain containing 4 (Atad4), mRNA. 91.6713 76.3957 68.4044 165.3991 164.6009 165.3143 35.9519 34.3864 27.6077 36.5995 36.6864 40.5569 39.0559 32.0998 32.3968 27.7166 38.1670 37.5245  
12 Rragd -1.09951 5.67937 6.77888 0.014578944 1354873 1434909_at Ras-related GTP binding D (Rragd), mRNA. 56.7200 47.7733 49.6660 130.7534 86.4200 117.1841 3024.5179 3064.9019 2926.5427 2833.6896 3053.8947 2886.1453 3077.3845 2649.4466 2940.1852 2696.1797 2956.0764 2761.1862
13 Ctsf -1.10155 8.30660 9.40815 0.015032786 1340886 1451019_at cathepsin F (Ctsf), mRNA. 372.3557 273.5287 311.6344 899.6148 576.9081 604.2813 791.0511 790.5906 872.6233 828.0332 792.6262 849.7496 810.4266 860.4396 749.3127 988.4214 883.3737 776.9676
14 Socs2 -1.10422 4.22756 5.33178 0.044046052 1343687 1418507_s_at Suppressor of cytokine signaling 2 (Socs2), mRNA 17.8044 20.1361 18.3384 49.2846 28.3416 46.7672 248.9299 268.4852 653.5010 643.1115 246.2027 725.4607 255.1171 453.8417 590.9852 134.6512 73.0052 94.5830
15   -1.12764 7.51998 8.64762 0.010980214 1367299 1456204_at Transcribed locus, strongly similar to NP_001118239.1 hypothetical protein LOC440957 [Homo sapiens] 199.8901 170.4654 181.4637 482.2465 326.8741 409.1942 381.4622 379.3611 434.9307 461.4152 376.8089 405.3658 285.6279 534.8928 481.0047 419.9378 371.6794 322.8209  
16 Fgg -1.13757 9.46173 10.59929 0.049718915 1327771 1416025_at fibrinogen gamma chain (Fgg), mRNA. 871.5681 569.6519 706.1201 1579.0987 2254.3835 1048.7630 33.9803 28.9203 48.1670 30.2012 27.1749 32.8562 25.5623 26.8776 29.4337 26.5491 27.9839 27.0691
17 Spata13 -1.17415 8.29268 9.46683 0.0017270212 1342264 1454656_at Spermatogenesis associated 13, mRNA (cDNA clone MGC:170080 IMAGE:8861475) 295.6559 361.7630 288.2847 722.2630 653.6039 750.5664 111.0391 109.8522 108.7760 80.7681 99.5872 88.3598 88.3286 107.6774 92.1693 129.9869 97.1084 111.0691
18 Ghr -1.18131 6.26565 7.44696 0.023284454 1348960 1451501_a_at growth hormone receptor (Ghr), transcript variant 3, mRNA. 95.7515 85.3192 55.7506 190.5392 185.6277 150.1912 1003.3660 961.7216 1082.0582 1040.4849 1025.1026 971.1339 1190.5078 1043.6210 1212.0408 1377.5632 1334.8007 1137.2823
19 Dnaja4 -1.20399 8.64099 9.84498 0.0018253591 1329834 1418592_at DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA. 363.2998 398.6748 439.2471 799.2239 919.1620 1058.8670 592.7230 585.9001 828.5892 798.7462 588.6662 792.4805 600.6055 563.9546 507.3355 773.4742 683.3550 538.9555
20 Rfk -1.20996 10.05413 11.26410 0.012327788 1327926 1416229_at riboflavin kinase (Rfk), mRNA. 979.6495 1075.5182 1140.5109 2999.7756 2512.5590 1973.7362 1230.5251 1280.2783 1465.9252 1408.1519 1280.9575 1419.1541 1418.5039 1443.6126 1541.6647 1409.9153 1377.7522 1325.7000
21 Clcn2 -1.22520 4.41119 5.63639 0.013266759 1339609 1449248_at chloride channel 2 (Clcn2), mRNA. 20.0007 26.3365 18.2852 42.1835 43.2541 67.4528 43.2910 37.6371 38.3638 38.0619 26.8502 38.2797 36.4858 37.3724 43.8882 35.4514 36.1328 38.5886
22 Spata13 -1.22913 7.46344 8.69257 0.018606018 1356572 1437865_at spermatogenesis associated 13 (Spata13), mRNA. 187.3526 208.9603 140.4213 411.2675 411.1863 418.8038 97.7408 93.8545 91.0838 79.2993 93.5580 94.4446 90.5016 92.7842 87.2703 96.6170 83.7337 87.9772
23 Dnaja4 -1.25760 9.04815 10.30575 0.0026042864 1337468 1434196_at DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA. 476.5445 563.7644 552.1969 1272.9513 1238.3512 1286.3662 963.2323 969.2812 928.1614 957.3741 961.9317 944.2608 931.6113 854.3488 702.5691 783.7269 1259.9573 790.9457
24 Odc1 -1.25898 11.04641 12.30539 0.0020210188 1346063 1427364_a_at ornithine decarboxylase, structural 1 (Odc1), mRNA. 2469.0588 1833.6796 2089.5172 5094.7275 4581.5947 5555.6635 758.9211 784.7345 1125.1624 1045.3071 789.7075 1049.0672 1682.9176 1113.2225 1816.3872 845.2527 743.7337 594.4004
25 Cd36 -1.29680 5.47789 6.77468 0.0073060718 1340774 1450884_at CD36 antigen, mRNA (cDNA clone MGC:6068 IMAGE:3481681) 39.1388 57.1148 39.5975 98.7144 123.9789 107.2559 1180.6251 1183.6537 1307.1572 1187.2650 1112.6408 1241.4490 1054.0154 1123.1509 903.8691 846.4051 917.9559 816.8495
26 Gpr150 -1.30245 6.33660 7.63906 0.00096615016 1364787 1447485_at G protein-coupled receptor 150, mRNA (cDNA clone MGC:148214 IMAGE:40107174) 80.4260 92.2921 71.1147 193.4357 179.4297 228.2041 40.6039 37.3218 37.7426 41.8892 38.7378 40.4878 51.0242 44.0883 44.0227 42.1911 43.0752 57.7051
27 Cd82 -1.32889 11.22979 12.55867 0.0033034567 1328061 1416401_at CD82 antigen (Cd82), transcript variant 2, mRNA. 2320.9894 2829.6883 2109.0908 6455.8466 5660.4998 6009.0201 763.2174 756.7914 896.0656 858.0582 729.7227 844.6883 1035.9603 767.4174 946.9220 721.6506 780.2827 571.6425
28   -1.33044 4.51723 5.84767 0.025238946 1350770 1428909_at Transcribed locus 31.5752 23.9949 15.8491 46.1837 67.4658 61.2917 169.0087 194.0938 141.4947 189.2132 210.5635 173.7236 132.9334 208.9297 240.2643 251.3593 182.5427 79.3205  
29 Fzd5 -1.39992 7.07836 8.47829 0.0083693082 1366993 1455604_at frizzled homolog 5 (Drosophila) (Fzd5), transcript variant 2, mRNA. 139.7764 163.7443 107.8449 330.3191 287.7759 477.1664 67.6061 59.3490 59.8689 53.4224 59.1540 53.0310 54.8123 58.2967 51.9127 66.1232 61.7586 41.0333
30 Stat5a -1.44942 4.10780 5.55722 0.0062547727 1348627 1450259_a_at signal transducer and activator of transcription 5A (Stat5a), mRNA. 13.8932 16.3582 22.5512 59.7969 39.8737 43.7828 25.8331 31.5116 82.9659 78.6861 31.5116 72.4687 166.3186 137.2517 149.8765 74.5429 65.4503 55.7989
31 Cd36 -1.45049 8.74991 10.20041 0.00050637538 1333195 1423166_at CD36 antigen (Cd36), transcript variant 5, mRNA. 379.3461 486.8553 432.0405 1122.0693 1329.1915 1092.1397 2598.5330 2717.8427 2871.6525 3001.6628 2736.9420 2944.8962 2797.5716 2932.8484 2751.6060 2768.6823 2894.5080 2155.8864
32 Ppm1e -1.53593 3.93365 5.46957 0.0017136379 1354916 1434990_at Protein phosphatase 1E (PP2C domain containing), mRNA (cDNA clone MGC:170530 IMAGE:8861925) 13.9641 17.0712 14.9679 47.5794 36.5826 49.9831 18.1659 16.1062 18.0413 18.3883 17.0495 14.5679 19.0553 18.3178 18.4741 20.3049 17.5379 20.2349
33 Ccrn4l -1.59679 9.03486 10.63165 0.023937466 1345554 1425837_a_at CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA. 494.4093 474.9598 614.5408 1407.8149 1181.4982 2400.8203 2294.9077 2190.1389 2245.2478 2252.6339 2259.5349 2327.4852 925.7221 950.2809 1215.3054 649.2134 764.0944 680.9244 rhythmic process
34 Gvin1 -1.61572 6.38305 7.99877 0.0082674284 1350962 1429184_at GTPase, very large interferon inducible 1 (Gvin1), transcript variant B, mRNA. 75.2787 66.1066 116.8282 323.1233 265.0227 195.4139 190.9974 193.6008 112.2185 124.8387 179.4459 132.5410 143.2000 94.8071 181.1619 259.3591 202.8283 114.4744
35 Stat5b -1.64926 5.26860 6.91787 0.0018573437 1344534 1422103_a_at signal transducer and activator of transcription 5B (Stat5b), mRNA. 36.8179 32.6977 47.5826 137.0905 121.0724 106.5132 195.1879 183.1424 842.1944 887.5067 193.3896 963.3258 1420.4606 1362.1924 1505.7619 301.7720 176.5317 187.4154
36 Ston2 -1.67702 6.31349 7.99051 0.00096699816 1355327 1435657_at stonin 2 (Ston2), mRNA. 93.0904 66.2764 81.5427 285.4860 215.7075 267.1162 282.0064 286.3120 306.6487 324.4460 289.8785 280.9539 601.0149 553.5963 453.5485 590.3444 562.3186 446.3992
37 Trp53bp1 -1.72283 8.69096 10.41380 0.030032419 1345980 1426956_a_at transformation related protein 53 binding protein 1 (Trp53bp1), mRNA. 660.1404 312.4127 342.2615 1290.7054 1273.4570 1544.4929 349.1785 330.2075 279.4258 299.0790 302.5891 278.3966 390.0216 344.1610 418.7813 384.1602 448.3342 308.2104
38 Cd36 -1.82117 8.36902 10.19019 0.0032191775 1348794 1450883_a_at CD36 antigen (Cd36), transcript variant 5, mRNA. 298.6091 398.8186 303.4571 1145.3741 1232.3186 1129.7630 2265.7785 2273.0619 2371.8988 2494.6733 2258.6341 2527.1640 2834.5730 2808.1519 2490.0488 2442.8572 2718.3968 2139.7849
39   -1.93829 5.09702 7.03531 0.00011176933 1352813 1431742_at Transcribed locus 36.5212 36.3106 30.2337 125.5968 120.8749 148.6645 21.0987 27.0838 24.2846 22.3089 19.9506 21.3659 22.5312 22.1812 18.2362 24.0501 16.4808 18.2531  
40 Tnfrsf21 -2.20578 7.09062 9.29639 0.00013857393 1332863 1422740_at tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA. 139.7737 121.2675 149.3812 632.3417 548.6958 716.4694 144.2691 152.8193 146.0964 134.5965 151.2223 139.6568 156.2494 147.0852 135.8287 143.9437 141.7213 146.4853
41 Tnfrsf21 -2.57734 7.76192 10.33926 0.00076077815 1348752 1450731_s_at tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA. 179.6531 198.5344 286.7091 1253.8892 1061.2710 1633.7834 492.3222 504.6833 371.3014 367.2456 478.7033 340.8597 429.6674 400.3462 401.6732 413.0708 418.2630 443.7768
42 Socs3 -2.59612 5.38726 7.98338 0.0065395123 1349871 1456212_x_at Suppressor of cytokine signaling 3 (Socs3), mRNA 48.9595 27.6735 54.1104 297.7746 226.1876 240.6310 2547.2819 2516.3176 501.8186 599.3431 2565.6128 644.3749 154.3001 149.3006 177.7507 288.0805 200.8621 249.8199  
43 Socs3 -2.88373 4.68207 7.56579 0.0010702287 1349775 1455899_x_at suppressor of cytokine signaling 3 (Socs3), mRNA. 22.6423 20.6528 36.1766 242.2528 152.9323 183.5801 3532.9631 3291.2873 758.4727 901.1034 3378.5646 879.0435 175.8772 212.4538 268.9634 380.5947 288.2147 403.0422
44 Apol11b -4.20960 3.41062 7.62022 0.00082666764 1371585 1440927_x_at Apolipoprotein L 11b (Apol11b), mRNA 9.9121 9.9725 12.1653 143.1459 227.7468 233.6210 9.4201 9.6246 9.9331 9.9334 10.1337 9.4649 9.9078 9.8482 9.6523 9.5480 9.6981 8.8654  
45 Apol11b -4.64701 3.55236 8.19937 0.0003222647 1368099 1457307_at Apolipoprotein L 11b (Apol11b), mRNA 11.0851 11.0851 13.1410 242.0964 279.7075 375.0408 12.0698 10.5350 11.2894 10.6782 11.7976 10.1105 9.9204 12.6395 10.9931 11.1843 10.3570 11.5033  


This Web page was derived in collaboration with GSP consortium members.

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Revised: Mon Sep 28 13:56:56 EDT 2009