Row
A
A
A
B
B
B
Row
Gene
A-B Mean Difference
A Mean (Stat5KO)
B Mean (WT)
A-B p-Value
Well ID
Feature ID
Description
EG001-01.Erythroid.Stat5KO.br1.noStim
EG001-02.Erythroid.Stat5KO.br2.noStim
EG001-03.Erythroid.Stat5KO.br3.noStim
EG001-04.Erythroid.WT.br1.noStim
EG001-05.Erythroid.WT.br2.noStim
EG001-06.Erythroid.WT.br3.noStim
Gene Ontology Terms
1
Rsad2
-1.00541
11.49063
12.49605
0.028431841
1337925
1436058_at
radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.
3553.7718
2629.5130
2549.8264
4510.3187
7803.5445
5477.1646
catalytic activity
defense response to virus
endoplasmic reticulum
iron ion binding
iron-sulfur cluster binding
membrane
metal ion binding
response to virus
2
Rfk
-1.01706
10.22975
11.24681
0.013241846
1327556
1415737_at
riboflavin kinase (Rfk), mRNA.
1059.9895
1371.2126
1191.1804
3052.1127
2355.5366
1996.1509
ATP binding
cytoplasm
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
riboflavin biosynthetic process
riboflavin kinase activity
transferase activity
zinc ion binding
3
4632432E15Rik
-1.03215
4.80835
5.84050
0.0042505687
1353617
1432885_at
RIKEN cDNA 4632432E15 gene
28.3046
24.6838
31.4849
68.7762
52.9439
51.6702
4
Rfk
-1.03490
10.06125
11.09615
0.020805506
1327927
1416230_at
riboflavin kinase (Rfk), mRNA.
1086.4877
1056.3993
1062.5740
2663.5479
2133.3686
1846.2630
ATP binding
cytoplasm
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
riboflavin biosynthetic process
riboflavin kinase activity
transferase activity
zinc ion binding
5
Socs3
-1.03648
7.14218
8.17866
0.004395647
1328194
1416576_at
suppressor of cytokine signaling 3 (Socs3), mRNA.
120.5971
155.6736
150.1349
347.2172
257.0916
272.5061
branching involved in embryonic placenta morphogenesis
intracellular signaling cascade
modification-dependent protein catabolic process
negative regulation of insulin receptor signaling pathway
negative regulation of signal transduction
placenta blood vessel development
positive regulation of cell differentiation
positive regulation of cell differentiation
protein binding
regulation of cell differentiation
regulation of cell differentiation
regulation of growth
regulation of protein amino acid phosphorylation
spongiotrophoblast differentiation
spongiotrophoblast differentiation
trophoblast giant cell differentiation
trophoblast giant cell differentiation
6
Rsad2
-1.04647
9.58681
10.63328
0.041430984
1331607
1421009_at
radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.
1039.0083
767.2390
570.4251
1238.0962
2215.4173
1460.8151
catalytic activity
defense response to virus
endoplasmic reticulum
iron ion binding
iron-sulfur cluster binding
membrane
metal ion binding
response to virus
7
-1.05571
6.81684
7.87255
0.0066383013
1356168
1437087_at
Transcribed locus
123.8638
114.2557
101.2511
280.9402
198.3253
231.0111
8
Trp53bp1
-1.06538
9.29707
10.36245
0.0090267392
1335793
1426957_at
transformation related protein 53 binding protein 1 (Trp53bp1), mRNA.
761.2545
526.6445
620.9314
1187.7547
1416.2861
1356.2756
cellular response to DNA damage stimulus
damaged DNA binding
DNA binding
DNA repair
intracellular
kinetochore
nucleus
protein binding
regulation of transcription, DNA-dependent
replication fork
response to DNA damage stimulus
telomeric DNA binding
transcription
transcription factor binding
9
Dnaja4
-1.06573
9.86453
10.93026
0.00033938429
1329833
1418591_at
DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA.
858.1519
967.6132
975.6519
1989.2497
2014.3242
1854.3332
heat shock protein binding
membrane
metal ion binding
protein folding
unfolded protein binding
zinc ion binding
10
Ucp2
-1.06715
9.05346
10.12061
0.017052203
1361995
1444566_at
Uncoupling protein 2 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:13955 IMAGE:4205625)
605.6519
591.2656
418.8741
1201.7630
1053.0408
1090.3186
binding
integral to membrane
membrane
mitochondrial inner membrane
mitochondrial transport
mitochondrion
mitochondrion
transport
11
Atad4
-1.07729
6.28994
7.36723
0.01279511
1354336
1433870_at
ATPase family, AAA domain containing 4 (Atad4), mRNA.
91.6713
76.3957
68.4044
165.3991
164.6009
165.3143
12
Rragd
-1.09951
5.67937
6.77888
0.014578944
1354873
1434909_at
Ras-related GTP binding D (Rragd), mRNA.
56.7200
47.7733
49.6660
130.7534
86.4200
117.1841
cytoplasm
GTP binding
nucleotide binding
nucleus
protein binding
13
Ctsf
-1.10155
8.30660
9.40815
0.015032786
1340886
1451019_at
cathepsin F (Ctsf), mRNA.
372.3557
273.5287
311.6344
899.6148
576.9081
604.2813
cysteine-type endopeptidase activity
cysteine-type peptidase activity
hydrolase activity
lysosome
peptidase activity
proteolysis
14
Socs2
-1.10422
4.22756
5.33178
0.044046052
1343687
1418507_s_at
Suppressor of cytokine signaling 2 (Socs2), mRNA
17.8044
20.1361
18.3384
49.2846
28.3416
46.7672
growth hormone receptor binding
intracellular signaling cascade
lactation
lactation
mammary gland alveolus development
mammary gland alveolus development
modification-dependent protein catabolic process
negative regulation of JAK-STAT cascade
negative regulation of multicellular organism growth
negative regulation of multicellular organism growth
negative regulation of signal transduction
positive regulation of neuron differentiation
regulation of growth
regulation of multicellular organism growth
15
-1.12764
7.51998
8.64762
0.010980214
1367299
1456204_at
Transcribed locus, strongly similar to NP_001118239.1 hypothetical protein LOC440957 [Homo sapiens]
199.8901
170.4654
181.4637
482.2465
326.8741
409.1942
16
Fgg
-1.13757
9.46173
10.59929
0.049718915
1327771
1416025_at
fibrinogen gamma chain (Fgg), mRNA.
871.5681
569.6519
706.1201
1579.0987
2254.3835
1048.7630
blood coagulation
calcium ion binding
cell cortex
extracellular region
fibrinogen complex
platelet activation
protein binding, bridging
protein polymerization
receptor binding
signal transduction
17
Spata13
-1.17415
8.29268
9.46683
0.0017270212
1342264
1454656_at
Spermatogenesis associated 13, mRNA (cDNA clone MGC:170080 IMAGE:8861475)
295.6559
361.7630
288.2847
722.2630
653.6039
750.5664
guanyl-nucleotide exchange factor activity
intracellular
intracellular signaling cascade
regulation of Rho protein signal transduction
Rho guanyl-nucleotide exchange factor activity
18
Ghr
-1.18131
6.26565
7.44696
0.023284454
1348960
1451501_a_at
growth hormone receptor (Ghr), transcript variant 3, mRNA.
95.7515
85.3192
55.7506
190.5392
185.6277
150.1912
2-oxoglutarate metabolic process
allantoin metabolic process
citrate metabolic process
creatine metabolic process
creatinine metabolic process
cytokine receptor activity
endocytosis
extracellular region
extrinsic to membrane
fatty acid metabolic process
growth hormone receptor activity
growth hormone receptor signaling pathway
integral to membrane
isoleucine metabolic process
membrane
nucleus
oxaloacetate metabolic process
peptide hormone binding
plasma membrane
positive regulation of peptidyl-tyrosine phosphorylation
protein binding
receptor activity
regulation of multicellular organism growth
succinate metabolic process
taurine metabolic process
valine metabolic process
19
Dnaja4
-1.20399
8.64099
9.84498
0.0018253591
1329834
1418592_at
DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA.
363.2998
398.6748
439.2471
799.2239
919.1620
1058.8670
heat shock protein binding
membrane
metal ion binding
protein folding
unfolded protein binding
zinc ion binding
20
Rfk
-1.20996
10.05413
11.26410
0.012327788
1327926
1416229_at
riboflavin kinase (Rfk), mRNA.
979.6495
1075.5182
1140.5109
2999.7756
2512.5590
1973.7362
ATP binding
cytoplasm
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
riboflavin biosynthetic process
riboflavin kinase activity
transferase activity
zinc ion binding
21
Clcn2
-1.22520
4.41119
5.63639
0.013266759
1339609
1449248_at
chloride channel 2 (Clcn2), mRNA.
20.0007
26.3365
18.2852
42.1835
43.2541
67.4528
cell differentiation involved in salivary gland development
chloride channel activity
chloride channel complex
chloride ion binding
chloride transport
integral to membrane
ion channel activity
ion transport
membrane
transport
voltage-gated chloride channel activity
voltage-gated ion channel activity
22
Spata13
-1.22913
7.46344
8.69257
0.018606018
1356572
1437865_at
spermatogenesis associated 13 (Spata13), mRNA.
187.3526
208.9603
140.4213
411.2675
411.1863
418.8038
guanyl-nucleotide exchange factor activity
intracellular
intracellular signaling cascade
regulation of Rho protein signal transduction
Rho guanyl-nucleotide exchange factor activity
23
Dnaja4
-1.25760
9.04815
10.30575
0.0026042864
1337468
1434196_at
DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA.
476.5445
563.7644
552.1969
1272.9513
1238.3512
1286.3662
heat shock protein binding
membrane
metal ion binding
protein folding
unfolded protein binding
zinc ion binding
24
Odc1
-1.25898
11.04641
12.30539
0.0020210188
1346063
1427364_a_at
ornithine decarboxylase, structural 1 (Odc1), mRNA.
2469.0588
1833.6796
2089.5172
5094.7275
4581.5947
5555.6635
carboxy-lyase activity
catalytic activity
cytosol
kidney development
lyase activity
ornithine decarboxylase activity
polyamine biosynthetic process
positive regulation of cell proliferation
25
Cd36
-1.29680
5.47789
6.77468
0.0073060718
1340774
1450884_at
CD36 antigen, mRNA (cDNA clone MGC:6068 IMAGE:3481681)
39.1388
57.1148
39.5975
98.7144
123.9789
107.2559
apoptotic cell clearance
cell adhesion
cholesterol transport
high-density lipoprotein binding
integral to membrane
membrane
protein binding
receptor activity
transport
26
Gpr150
-1.30245
6.33660
7.63906
0.00096615016
1364787
1447485_at
G protein-coupled receptor 150, mRNA (cDNA clone MGC:148214 IMAGE:40107174)
80.4260
92.2921
71.1147
193.4357
179.4297
228.2041
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
integral to membrane
membrane
plasma membrane
receptor activity
signal transducer activity
signal transduction
27
Cd82
-1.32889
11.22979
12.55867
0.0033034567
1328061
1416401_at
CD82 antigen (Cd82), transcript variant 2, mRNA.
2320.9894
2829.6883
2109.0908
6455.8466
5660.4998
6009.0201
integral to membrane
membrane
28
-1.33044
4.51723
5.84767
0.025238946
1350770
1428909_at
Transcribed locus
31.5752
23.9949
15.8491
46.1837
67.4658
61.2917
29
Fzd5
-1.39992
7.07836
8.47829
0.0083693082
1366993
1455604_at
frizzled homolog 5 (Drosophila) (Fzd5), transcript variant 2, mRNA.
139.7764
163.7443
107.8449
330.3191
287.7759
477.1664
angiogenesis
cell differentiation
cell maturation
cell surface receptor linked signal transduction
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
Golgi apparatus
integral to membrane
membrane
multicellular organismal development
non-G-protein coupled 7TM receptor activity
plasma membrane
protein binding
receptor activity
signal transducer activity
signal transduction
transmembrane receptor activity
Wnt receptor signaling pathway
30
Stat5a
-1.44942
4.10780
5.55722
0.0062547727
1348627
1450259_a_at
signal transducer and activator of transcription 5A (Stat5a), mRNA.
13.8932
16.3582
22.5512
59.7969
39.8737
43.7828
calcium ion binding
cytokine-mediated signaling pathway
cytoplasm
development of secondary female sexual characteristics
development of secondary male sexual characteristics
development of secondary male sexual characteristics
DNA binding
epithelial cell differentiation involved in prostate gland development
female pregnancy
JAK-STAT cascade
lactation
lipid storage
luteinization
mammary gland development
natural killer cell differentiation
negative regulation of apoptosis
negative regulation of erythrocyte differentiation
negative regulation of mast cell apoptosis
nucleus
peptidyl-tyrosine phosphorylation
Peyer's patch development
positive regulation of activated T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of B cell differentiation
positive regulation of cell proliferation
positive regulation of cell proliferation
positive regulation of gamma-delta T cell differentiation
positive regulation of inflammatory response
positive regulation of interleukin-2 biosynthetic process
positive regulation of lymphocyte differentiation
positive regulation of mast cell differentiation
positive regulation of mast cell proliferation
positive regulation of mitotic cell cycle
positive regulation of multicellular organism growth
positive regulation of natural killer cell differentiation
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of survival gene product expression
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
prostate gland epithelium morphogenesis
protein binding
regulation of cell adhesion
regulation of epithelial cell differentiation
regulation of steroid metabolic process
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
response to peptide hormone stimulus
signal transducer activity
signal transduction
T cell differentiation in the thymus
T cell homeostasis
transcription
transcription factor activity
31
Cd36
-1.45049
8.74991
10.20041
0.00050637538
1333195
1423166_at
CD36 antigen (Cd36), transcript variant 5, mRNA.
379.3461
486.8553
432.0405
1122.0693
1329.1915
1092.1397
apoptotic cell clearance
cell adhesion
cholesterol transport
high-density lipoprotein binding
integral to membrane
membrane
protein binding
receptor activity
transport
32
Ppm1e
-1.53593
3.93365
5.46957
0.0017136379
1354916
1434990_at
Protein phosphatase 1E (PP2C domain containing), mRNA (cDNA clone MGC:170530 IMAGE:8861925)
13.9641
17.0712
14.9679
47.5794
36.5826
49.9831
catalytic activity
cytoplasm
hydrolase activity
magnesium ion binding
manganese ion binding
metal ion binding
nucleus
phosphoprotein phosphatase activity
protein amino acid dephosphorylation
protein serine/threonine phosphatase activity
protein serine/threonine phosphatase complex
33
Ccrn4l
-1.59679
9.03486
10.63165
0.023937466
1345554
1425837_a_at
CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA.
494.4093
474.9598
614.5408
1407.8149
1181.4982
2400.8203
rhythmic process
34
Gvin1
-1.61572
6.38305
7.99877
0.0082674284
1350962
1429184_at
GTPase, very large interferon inducible 1 (Gvin1), transcript variant B, mRNA.
75.2787
66.1066
116.8282
323.1233
265.0227
195.4139
cytoplasm
GTP binding
nucleotide binding
nucleus
35
Stat5b
-1.64926
5.26860
6.91787
0.0018573437
1344534
1422103_a_at
signal transducer and activator of transcription 5B (Stat5b), mRNA.
36.8179
32.6977
47.5826
137.0905
121.0724
106.5132
calcium ion binding
cytokine-mediated signaling pathway
cytoplasm
development of secondary female sexual characteristics
development of secondary male sexual characteristics
development of secondary male sexual characteristics
DNA binding
female pregnancy
female pregnancy
JAK-STAT cascade
lactation
lipid storage
luteinization
natural killer cell differentiation
negative regulation of apoptosis
negative regulation of erythrocyte differentiation
nucleus
Peyer's patch development
positive regulation of activated T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of B cell differentiation
positive regulation of cell proliferation
positive regulation of gamma-delta T cell differentiation
positive regulation of inflammatory response
positive regulation of interleukin-2 biosynthetic process
positive regulation of lymphocyte differentiation
positive regulation of mitotic cell cycle
positive regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of natural killer cell differentiation
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell proliferation
positive regulation of survival gene product expression
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
progesterone metabolic process
protein binding
regulation of cell adhesion
regulation of epithelial cell differentiation
regulation of steroid metabolic process
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
response to interleukin-15
response to interleukin-2
response to interleukin-4
sex differentiation
signal transducer activity
signal transduction
T cell differentiation in the thymus
T cell homeostasis
transcription
transcription factor activity
36
Ston2
-1.67702
6.31349
7.99051
0.00096699816
1355327
1435657_at
stonin 2 (Ston2), mRNA.
93.0904
66.2764
81.5427
285.4860
215.7075
267.1162
clathrin adaptor complex
cytoplasm
endocytosis
intracellular protein transport
membrane
protein binding
regulation of endocytosis
vesicle-mediated transport
37
Trp53bp1
-1.72283
8.69096
10.41380
0.030032419
1345980
1426956_a_at
transformation related protein 53 binding protein 1 (Trp53bp1), mRNA.
660.1404
312.4127
342.2615
1290.7054
1273.4570
1544.4929
cellular response to DNA damage stimulus
damaged DNA binding
DNA binding
DNA repair
intracellular
kinetochore
nucleus
protein binding
regulation of transcription, DNA-dependent
replication fork
response to DNA damage stimulus
telomeric DNA binding
transcription
transcription factor binding
38
Cd36
-1.82117
8.36902
10.19019
0.0032191775
1348794
1450883_a_at
CD36 antigen (Cd36), transcript variant 5, mRNA.
298.6091
398.8186
303.4571
1145.3741
1232.3186
1129.7630
apoptotic cell clearance
cell adhesion
cholesterol transport
high-density lipoprotein binding
integral to membrane
membrane
protein binding
receptor activity
transport
39
-1.93829
5.09702
7.03531
0.00011176933
1352813
1431742_at
Transcribed locus
36.5212
36.3106
30.2337
125.5968
120.8749
148.6645
40
Tnfrsf21
-2.20578
7.09062
9.29639
0.00013857393
1332863
1422740_at
tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA.
139.7737
121.2675
149.3812
632.3417
548.6958
716.4694
apoptosis
axon
integral to membrane
membrane
neuron apoptosis
protein binding
receptor activity
signal transduction
41
Tnfrsf21
-2.57734
7.76192
10.33926
0.00076077815
1348752
1450731_s_at
tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA.
179.6531
198.5344
286.7091
1253.8892
1061.2710
1633.7834
apoptosis
axon
integral to membrane
membrane
neuron apoptosis
protein binding
receptor activity
signal transduction
42
Socs3
-2.59612
5.38726
7.98338
0.0065395123
1349871
1456212_x_at
Suppressor of cytokine signaling 3 (Socs3), mRNA
48.9595
27.6735
54.1104
297.7746
226.1876
240.6310
43
Socs3
-2.88373
4.68207
7.56579
0.0010702287
1349775
1455899_x_at
suppressor of cytokine signaling 3 (Socs3), mRNA.
22.6423
20.6528
36.1766
242.2528
152.9323
183.5801
branching involved in embryonic placenta morphogenesis
intracellular signaling cascade
modification-dependent protein catabolic process
negative regulation of insulin receptor signaling pathway
negative regulation of signal transduction
placenta blood vessel development
positive regulation of cell differentiation
positive regulation of cell differentiation
protein binding
regulation of cell differentiation
regulation of cell differentiation
regulation of growth
regulation of protein amino acid phosphorylation
spongiotrophoblast differentiation
spongiotrophoblast differentiation
trophoblast giant cell differentiation
trophoblast giant cell differentiation
44
Apol11b
-4.20960
3.41062
7.62022
0.00082666764
1371585
1440927_x_at
Apolipoprotein L 11b (Apol11b), mRNA
9.9121
9.9725
12.1653
143.1459
227.7468
233.6210
45
Apol11b
-4.64701
3.55236
8.19937
0.0003222647
1368099
1457307_at
Apolipoprotein L 11b (Apol11b), mRNA
11.0851
11.0851
13.1410
242.0964
279.7075
375.0408