Row
Row
Gene
A-B Mean Difference
A Mean (Stat5MKO+GH)
B Mean (Stat5MKO-GH)
A-B p-Value
Well ID
Feature ID
Description
Gene Ontology Terms
1
Rrad
5.08245
11.46275
6.38030
0.00015515705
1332723
1422562_at
Ras-related associated with diabetes (Rrad), mRNA
calmodulin binding
GTP binding
nucleotide binding
small GTPase mediated signal transduction
2
Mt2
4.35345
14.56789
10.21444
0.0045445599
1336865
1428942_at
metallothionein 2 (Mt2), mRNA.
cellular zinc ion homeostasis
detoxification of copper ion
metal ion binding
nitric oxide mediated signal transduction
zinc ion binding
3
Egr1
4.08556
12.21400
8.12844
1.2099936e-07
1328588
1417065_at
early growth response 1 (Egr1), mRNA.
DNA binding
intracellular
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
nucleic acid binding
nucleus
nucleus
regulation of transcription, DNA-dependent
response to protein stimulus
T cell differentiation
transcription
transcription factor activity
zinc ion binding
4
Lcn2
3.81650
9.28885
5.47235
0.00083893737
1346214
1427747_a_at
lipocalin 2 (Lcn2), mRNA.
binding
extracellular region
response to virus
transport
transporter activity
5
Hbegf
3.71326
12.05241
8.33915
0.00020409707
1329643
1418350_at
heparin-binding EGF-like growth factor (Hbegf), mRNA.
epidermal growth factor receptor signaling pathway
extracellular region
integral to membrane
membrane
plasma membrane
regulation of heart contraction
6
Ankrd1
3.56696
10.60629
7.03932
0.0060880467
1331592
1420992_at
ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA.
cytoplasm
I band
nucleus
protein binding
regulation of transcription from RNA polymerase II promoter
transcription corepressor activity
transcription factor complex
7
Mt1
3.43439
14.09275
10.65836
0.006116709
1344655
1422557_s_at
metallothionein 1 (Mt1), mRNA.
cellular metal ion homeostasis
cellular zinc ion homeostasis
copper ion binding
cytosol
detoxification of copper ion
lysosome
metal ion binding
nitric oxide mediated signal transduction
zinc ion binding
8
Socs3
3.38393
11.31231
7.92838
0.001942104
1349871
1456212_x_at
Suppressor of cytokine signaling 3 (Socs3), mRNA
9
Ankrd1
3.37045
10.93361
7.56316
0.0082673731
1331591
1420991_at
ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA.
cytoplasm
I band
nucleus
protein binding
regulation of transcription from RNA polymerase II promoter
transcription corepressor activity
transcription factor complex
10
3.27943
7.32333
4.04389
3.379342e-06
1355275
1435579_at
Transcribed locus
11
Socs3
3.26513
11.73110
8.46597
0.0014827499
1349775
1455899_x_at
suppressor of cytokine signaling 3 (Socs3), mRNA.
branching involved in embryonic placenta morphogenesis
intracellular signaling cascade
modification-dependent protein catabolic process
negative regulation of insulin receptor signaling pathway
negative regulation of signal transduction
placenta blood vessel development
positive regulation of cell differentiation
positive regulation of cell differentiation
protein binding
regulation of cell differentiation
regulation of cell differentiation
regulation of growth
regulation of protein amino acid phosphorylation
spongiotrophoblast differentiation
spongiotrophoblast differentiation
trophoblast giant cell differentiation
trophoblast giant cell differentiation
12
3.10325
10.23761
7.13437
0.0017046598
1362958
1445562_at
ESTs
13
4930513N20Rik
3.08640
10.77309
7.68669
0.0017335498
1353873
1433148_at
RIKEN cDNA 4930513N20 gene
14
Hbegf
3.07271
10.63457
7.56186
0.00026031051
1329642
1418349_at
heparin-binding EGF-like growth factor (Hbegf), mRNA.
epidermal growth factor receptor signaling pathway
extracellular region
integral to membrane
membrane
plasma membrane
regulation of heart contraction
15
Mt1
3.04896
8.87727
5.82830
1.5708628e-05
1341305
1451612_at
Metallothionein 1, mRNA (cDNA clone MGC:47147 IMAGE:4990006)
cellular metal ion homeostasis
cellular zinc ion homeostasis
copper ion binding
cytosol
detoxification of copper ion
lysosome
metal ion binding
nitric oxide mediated signal transduction
zinc ion binding
16
Sgms2
3.04465
7.32413
4.27948
0.0024061758
1350626
1428663_at
sphingomyelin synthase 2 (Sgms2), mRNA.
ceramide cholinephosphotransferase activity
Golgi apparatus
integral to Golgi membrane
integral to membrane
integral to plasma membrane
kinase activity
lipid metabolic process
membrane
plasma membrane
sphingolipid metabolic process
sphingomyelin biosynthetic process
sphingomyelin synthase activity
transferase activity
17
Fam107a
3.02943
9.51959
6.49016
0.00050422278
1371171
1434202_a_at
Family with sequence similarity 107, member A (Fam107a), mRNA
18
2.87694
8.24911
5.37217
0.0012348887
1359551
1441799_at
ESTs
19
LOC100046817
2.85712
9.13872
6.28160
3.3915162e-09
1364367
1447016_at
PREDICTED: hypothetical protein LOC100046817 (LOC100046817), mRNA.
20
2.80577
7.29554
4.48977
0.0028937442
1359586
1441858_at
Unknown
21
2.79216
8.51603
5.72387
0.011886831
1368114
1457324_at
Transcribed locus
22
S100a9
2.79171
8.15988
5.36817
0.00054135068
1339204
1448756_at
S100 calcium binding protein A9 (calgranulin B) (S100a9), mRNA.
actin cytoskeleton reorganization
calcium ion binding
leukocyte chemotaxis
regulation of integrin biosynthetic process
23
Btg2
2.78914
12.61367
9.82453
0.017096455
1327943
1416250_at
B-cell translocation gene 2, anti-proliferative (Btg2), mRNA.
anterior/posterior pattern formation
negative regulation of apoptosis
neuron differentiation
protein amino acid methylation
protein binding
regulation of transcription, DNA-dependent
response to DNA damage stimulus
transcription
24
Runx1
2.72128
7.99822
5.27693
0.0018638421
1332965
1422864_at
runt related transcription factor 1 (Runx1), transcript variant 2, mRNA.
ATP binding
behavioral response to pain
central nervous system development
definitive hemopoiesis
DNA binding
embryonic hemopoiesis
in utero embryonic development
liver development
neuron development
neuron differentiation
nucleus
positive regulation of angiogenesis
protein binding
regulation of transcription, DNA-dependent
response to retinoic acid
skeletal system development
transcription
transcription factor activity
25
Ddit4
2.65793
11.00698
8.34906
0.0032257794
1336689
1428306_at
DNA-damage-inducible transcript 4 (Ddit4), mRNA.
apoptosis
cytoplasm
negative regulation of signal transduction
26
Socs3
2.64092
11.41723
8.77632
0.0025947609
1328194
1416576_at
suppressor of cytokine signaling 3 (Socs3), mRNA.
branching involved in embryonic placenta morphogenesis
intracellular signaling cascade
modification-dependent protein catabolic process
negative regulation of insulin receptor signaling pathway
negative regulation of signal transduction
placenta blood vessel development
positive regulation of cell differentiation
positive regulation of cell differentiation
protein binding
regulation of cell differentiation
regulation of cell differentiation
regulation of growth
regulation of protein amino acid phosphorylation
spongiotrophoblast differentiation
spongiotrophoblast differentiation
trophoblast giant cell differentiation
trophoblast giant cell differentiation
27
2.63623
11.91501
9.27878
0.0036623631
1364970
1447891_at
Unknown
28
Selp
2.62080
9.40576
6.78496
0.0057342101
1331270
1420558_at
selectin, platelet (Selp), mRNA.
binding
calcium-dependent protein binding
cell adhesion
external side of plasma membrane
glycoprotein binding
heterophilic cell adhesion
inflammatory response
integral to membrane
leukocyte adhesion
leukocyte tethering or rolling
membrane
membrane fraction
platelet alpha granule membrane
protein binding
sialic acid binding
sugar binding
29
Srxn1
2.61964
11.16634
8.54670
0.0036942953
1345965
1426875_s_at
sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA.
antioxidant activity
ATP binding
cytoplasm
cytosol
magnesium ion binding
nucleotide binding
oxidation reduction
oxidoreductase activity
response to oxidative stress
sulfiredoxin activity
30
2.58049
8.78043
6.19994
3.4575875e-05
1358216
1440347_at
Transcribed locus
31
2.56638
9.86881
7.30243
0.0010411162
1362387
1444973_at
ESTs
32
Srxn1
2.55379
12.03382
9.48003
0.0036417059
1341347
1451680_at
sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA.
antioxidant activity
ATP binding
cytoplasm
cytosol
magnesium ion binding
nucleotide binding
oxidation reduction
oxidoreductase activity
response to oxidative stress
sulfiredoxin activity
33
2.51254
7.73207
5.21953
0.00013741165
1368884
1458179_at
ESTs
34
Map3k6
2.50098
8.71669
6.21571
9.170108e-05
1348516
1449901_a_at
mitogen-activated protein kinase kinase kinase 6 (Map3k6), mRNA.
ATP binding
kinase activity
magnesium ion binding
MAP kinase kinase kinase activity
metal ion binding
nucleotide binding
protein amino acid phosphorylation
protein binding
protein kinase activity
protein serine/threonine kinase activity
transferase activity
35
Kcnma1
2.44520
5.72907
3.28387
0.0050078501
1367837
1457018_at
Calcium-activated potassium channel SLO1 mRNA, complete cds, alternatively spliced
adult walking behavior
apical plasma membrane
auditory receptor cell differentiation
binding
calcium ion binding
calcium-activated potassium channel activity
calcium-activated potassium channel activity
calcium-activated potassium channel activity
catalytic activity
cell maturation
circadian rhythm
cytoplasmic part
endoplasmic reticulum
external side of plasma membrane
eye blink reflex
integral to membrane
integral to membrane
ion channel activity
ion transport
large conductance calcium-activated potassium channel activity
large conductance calcium-activated potassium channel activity
locomotor rhythm
magnesium ion binding
membrane
metabolic process
metal ion binding
micturition
negative regulation of cell volume
neuromuscular process controlling balance
plasma membrane
postsynaptic membrane
potassium channel activity
potassium channel activity
potassium ion binding
potassium ion transport
protein binding
protein homooligomerization
regulation of action potential in neuron
regulation of aldosterone metabolic process
regulation of membrane potential
regulation of membrane potential
relaxation of vascular smooth muscle
response to hypoxia
saliva secretion
sensory perception of sound
sensory perception of sound
smooth muscle contraction involved in micturition
synaptic transmission
terminal button
transport
vasodilation
voltage-gated ion channel activity
voltage-gated potassium channel activity
voltage-gated potassium channel activity
voltage-gated potassium channel complex
36
S100a8
2.43459
8.09073
5.65614
0.0020670409
1343853
1419394_s_at
S100 calcium binding protein A8 (calgranulin A) (S100a8), mRNA.
calcium ion binding
chemotaxis
37
2.42416
9.60806
7.18390
0.0010525991
1356604
1437916_at
Transcribed locus
38
Sdc4
2.42244
10.90333
8.48089
0.03470996
1348292
1448793_a_at
syndecan 4 (Sdc4), mRNA.
cell surface
cytoskeletal protein binding
integral to membrane
membrane
39
2.41867
8.87634
6.45767
0.0012329286
1363613
1446245_at
Mus musculus 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030463N01 product:unknown EST, full insert sequence.
40
2.35432
9.64778
7.29346
0.00061389231
1363963
1446598_at
Transcribed locus
41
Nab2
2.35342
9.85902
7.50560
0.00013282566
1329299
1417930_at
Ngfi-A binding protein 2 (Nab2), transcript variant 2, mRNA.
endochondral ossification
myelination
negative regulation of transcription
nucleus
regulation of epidermis development
regulation of transcription
regulation of transcription, DNA-dependent
Schwann cell differentiation
transcription
transcription regulator activity
transcription repressor activity
42
Limch1
2.34974
8.79673
6.44699
0.0029840383
1358631
1440776_at
LIM and calponin homology domains 1 (Limch1), mRNA
actin binding
actomyosin structure organization
metal ion binding
zinc ion binding
43
2.33686
8.26490
5.92804
0.00060293683
1357961
1440051_at
Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230017C05 product:hypothetical protein, full insert sequence.
44
2.31905
9.54273
7.22369
0.0011517525
1372399
1456209_x_at
Transcribed locus
45
2.31420
9.48873
7.17453
0.01014073
1370187
1459557_at
ESTs
46
Fkbp5
2.31315
11.75781
9.44466
0.00049567336
1327844
1416125_at
FK506 binding protein 5 (Fkbp5), mRNA.
binding
cytoplasm
isomerase activity
nucleus
peptidyl-prolyl cis-trans isomerase activity
protein binding
protein folding
47
2.31092
7.35102
5.04010
0.00051526038
1370809
1420312_s_at
Unknown
48
2.30855
8.97416
6.66561
0.00040537873
1363841
1446475_at
Transcribed locus
49
Xirp1
2.29136
12.84949
10.55813
0.012238767
1330359
1419220_at
Xin
actin binding
actin cytoskeleton organization
cardiac muscle cell development
cell junction
cell-cell adherens junction
fascia adherens
filamin-C binding
heart morphogenesis
intercalated disc
negative regulation of cell proliferation
protein binding
regulation of membrane potential
sarcomere organization
50
2.28627
6.75124
4.46497
0.0020931879
1360542
1442967_at
Transcribed locus
51
2.27949
7.68029
5.40080
0.030598228
1357431
1439412_at
ESTs
52
Cebpd
2.25984
11.90820
9.64836
0.0037820971
1333245
1423233_at
CCAAT/enhancer binding protein (C/EBP), delta (Cebpd), mRNA
DNA binding
nucleus
positive regulation of transcription from RNA polymerase II promoter
promoter binding
protein binding
protein dimerization activity
protein heterodimerization activity
protein homodimerization activity
regulation of transcription, DNA-dependent
sequence-specific DNA binding
specific RNA polymerase II transcription factor activity
transcription
transcription factor activity
53
2.25715
9.18189
6.92474
0.032253691
1360020
1442395_at
Transcribed locus
54
Gadd45a
2.24790
10.50217
8.25427
0.011280511
1339832
1449519_at
growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), mRNA.
cell cycle
cell cycle arrest
centrosome cycle
negative regulation of protein kinase activity
nucleus
protein binding
regulation of cell cycle
response to DNA damage stimulus
55
Sh3bp2
2.24295
9.30839
7.06544
0.00017992311
1338857
1448328_at
SH3-domain binding protein 2 (Sh3bp2), transcript variant d, mRNA.
protein binding
SH3 domain binding
56
2.17016
10.71744
8.54728
0.003997732
1350162
AFFX-r2-Bs-dap-3_at
57
2.16371
6.97859
4.81488
0.01172417
1363536
1446167_at
Mus musculus 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930417E23 product:unknown EST, full insert sequence.
58
2.16110
6.50169
4.34060
0.00092177589
1360780
1443212_at
ESTs
59
2.16106
6.58408
4.42302
0.00040049656
1360328
1442725_at
Transcribed locus
60
2.15249
10.24915
8.09666
0.0030481436
1350142
AFFX-DapX-3_at
B. subtilis GEN=jojG DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2684-3130 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carbox
61
2.15092
8.71990
6.56898
5.0772311e-05
1363514
1446141_at
Mus musculus 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130049J04 product:unclassifiable, full insert sequence.
62
2.12510
8.44107
6.31597
0.00014939259
1362800
1445398_at
Transcribed locus
63
AB041803
2.12307
7.49392
5.37085
0.0052350661
1342983
1460417_at
PREDICTED: cDNA sequence AB041803 (AB041803), misc RNA.
64
2.11570
7.61431
5.49860
0.0022858935
1368796
1458089_at
Transcribed locus
65
Btg2
2.11492
11.99107
9.87615
0.012793634
1338812
1448272_at
B-cell translocation gene 2, anti-proliferative (Btg2), mRNA.
anterior/posterior pattern formation
negative regulation of apoptosis
neuron differentiation
protein amino acid methylation
protein binding
regulation of transcription, DNA-dependent
response to DNA damage stimulus
transcription
66
2.11376
8.74000
6.62623
0.018845426
1371637
1441843_s_at
Transcribed locus
67
2.10679
8.53967
6.43288
5.5560204e-05
1370044
1459409_at
Mus musculus adult male cecum cDNA, RIKEN full-length enriched library, clone:9130014A12 product:unclassifiable, full insert sequence.
68
B3galnt2
2.06893
7.32627
5.25734
0.0029006618
1360350
1442750_at
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2, mRNA (cDNA clone MGC:103263 IMAGE:30735904)
acetylgalactosaminyltransferase activity
galactosyltransferase activity
Golgi apparatus
integral to membrane
membrane
protein amino acid glycosylation
transferase activity
transferase activity, transferring glycosyl groups
UDP-N-acetylgalactosamine metabolic process
69
B130066H01Rik
2.05975
6.12029
4.06053
0.0046651649
1363875
1446509_at
RIKEN cDNA B130066H01 gene
70
Zbtb16
2.04052
11.87282
9.83230
0.00054159063
1357281
1439163_at
PLZF gene
anterior/posterior pattern formation
DNA binding
embryonic hindlimb morphogenesis
embryonic limb morphogenesis
embryonic pattern specification
forelimb morphogenesis
leg morphogenesis
male germ-line stem cell division
metal ion binding
negative regulation of cell proliferation
negative regulation of transcription, DNA-dependent
nucleus
nucleus
positive regulation of apoptosis
protein binding
protein binding
regulation of transcription
skeletal system development
specific transcriptional repressor activity
transcriptional repressor complex
zinc ion binding
71
Slc10a6
2.03537
9.12678
7.09140
0.0016525242
1336820
1428776_at
Solute carrier family 10 (sodium/bile acid cotransporter family), member 6 (Slc10a6), mRNA
bile acid:sodium symporter activity
integral to membrane
ion transport
membrane
sodium ion binding
sodium ion transport
symporter activity
transport
72
Sbno2
2.03135
6.82704
4.79569
0.0046872247
1368999
1458308_at
Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209)
macrophage activation during immune response
negative regulation of transcription, DNA-dependent
regulation of inflammatory response
regulation of transcription, DNA-dependent
transcription
transcription repressor activity
73
2.02818
8.44556
6.41739
8.2756879e-06
1359131
1441360_at
ESTs, Moderately similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus]
74
Phlda1
2.01755
10.26445
8.24690
0.0068075784
1330049
1418835_at
pleckstrin homology-like domain, family A, member 1 (Phlda1), mRNA.
apoptosis
cytoplasm
cytoplasmic vesicle
FasL biosynthetic process
membrane
nucleus
75
Junb
2.01744
10.60109
8.58365
0.0084018217
1327679
1415899_at
Jun-B oncogene, mRNA (cDNA clone MGC:6021 IMAGE:3592704)
cellular process
decidualization
DNA binding
embryonic process involved in female pregnancy
in utero embryonic development
labyrinthine layer blood vessel development
nucleus
positive regulation of cell differentiation
protein dimerization activity
regulation of cell cycle
regulation of transcription, DNA-dependent
sequence-specific DNA binding
transcription
transcription factor activity
trophectodermal cell differentiation
trophectodermal cell differentiation
vasculogenesis
76
2.00268
8.44488
6.44220
0.0001011392
1363243
1445866_at
ESTs
77
2.00074
8.35018
6.34945
0.0027573921
1362797
1445395_at
Transcribed locus
78
Tgfb2
1.95555
10.02264
8.06710
3.4088549e-06
1344806
1423250_a_at
transforming growth factor, beta 2 (Tgfb2), mRNA.
activation-induced cell death of T cells
axon
axon guidance
blood vessel development
blood vessel remodeling
cartilage condensation
cell growth
cell proliferation
cell soma
dopamine biosynthetic process
extracellular matrix organization
extracellular region
extracellular space
growth
growth factor activity
hair follicle development
hair follicle morphogenesis
heart development
hemopoiesis
induction of apoptosis
negative regulation of keratinocyte differentiation
neuron development
neuron fate commitment
pathway-restricted SMAD protein phosphorylation
positive regulation of cell cycle
protein binding
regulation of apoptosis
skeletal system development
somatic stem cell division
transforming growth factor beta receptor binding
79
1.94683
8.81486
6.86804
0.0022793629
1363341
1445966_at
Transcribed locus
80
Adamts9
1.91954
7.42303
5.50349
0.021963542
1351838
1430352_at
MKIAA1312 protein
endopeptidase activity
extracellular space
metallopeptidase activity
positive regulation of melanocyte differentiation
proteinaceous extracellular matrix
proteolysis
proteolysis
regulation of pigmentation during development
81
Agfg2
1.91396
7.21212
5.29816
0.0034930636
1334842
1425362_at
ArfGAP with FG repeats 2 (Agfg2), transcript variant 1, mRNA.
ARF GTPase activator activity
metal ion binding
regulation of ARF GTPase activity
zinc ion binding
82
Fam107a
1.90833
8.48558
6.57725
0.0005297996
1354513
1434203_at
family with sequence similarity 107, member A (Fam107a), mRNA.
83
1.89031
9.17141
7.28109
6.2074994e-05
1367806
1456986_at
Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430208D19 product:unknown EST, full insert sequence.
84
Cish
1.88487
10.20218
8.31732
0.047666364
1339177
1448724_at
cytokine inducible SH2-containing protein (Cish), mRNA.
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
intracellular signaling cascade
modification-dependent protein catabolic process
negative regulation of signal transduction
plasma membrane
protein binding
regulation of growth
85
1.88374
9.87720
7.99346
0.00017946645
1337418
1434025_at
Transcribed locus
86
Cdkn1a
1.88304
10.89782
9.01478
0.013621537
1334343
1424638_at
cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.
cell cycle
cell cycle arrest
cyclin binding
cyclin-dependent protein kinase holoenzyme complex
cyclin-dependent protein kinase inhibitor activity
cytoplasm
cytosol
kinase activity
metal ion binding
negative regulation of apoptosis
negative regulation of cell proliferation
negative regulation of cyclin-dependent protein kinase activity
nucleus
positive regulation of B cell proliferation
positive regulation of programmed cell death
protein binding
protein kinase inhibitor activity
regulation of cell cycle
response to DNA damage stimulus
response to UV
zinc ion binding
87
1.87737
8.33933
6.46196
0.013711582
1363152
1445774_at
Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330037B11 product:unknown EST, full insert sequence.
88
Zbtb16
1.87375
9.00250
7.12874
0.0050888062
1336304
1427638_at
zinc finger and BTB domain containing 16 (Zbtb16), mRNA.
anterior/posterior pattern formation
DNA binding
embryonic hindlimb morphogenesis
embryonic limb morphogenesis
embryonic pattern specification
forelimb morphogenesis
leg morphogenesis
male germ-line stem cell division
metal ion binding
negative regulation of cell proliferation
negative regulation of transcription, DNA-dependent
nucleus
nucleus
positive regulation of apoptosis
protein binding
protein binding
regulation of transcription
skeletal system development
specific transcriptional repressor activity
transcriptional repressor complex
zinc ion binding
89
Klf5
1.87286
10.91067
9.03781
0.00029070513
1348818
1451021_a_at
Kruppel-like factor 5 (Klf5), mRNA.
angiogenesis
DNA binding
DNA binding
intracellular
metal ion binding
microvillus assembly
nucleic acid binding
nucleus
positive regulation of transcription
protein binding
regulation of transcription, DNA-dependent
transcription
transcription factor activity
transcription factor activity
zinc ion binding
90
5830427D03Rik
1.86871
8.46326
6.59454
0.00023444939
1352101
1430702_at
RIKEN cDNA 5830427D03 gene (5830427D03Rik), mRNA.
91
Atf3
1.85892
10.98709
9.12817
0.04804646
1339701
1449363_at
activating transcription factor 3 (Atf3), mRNA.
DNA binding
gluconeogenesis
nucleus
protein dimerization activity
regulation of transcription, DNA-dependent
sequence-specific DNA binding
transcription
transcription factor activity
transcription factor complex
transcription repressor activity
92
1.84422
10.05567
8.21145
0.0083254007
1360313
1442710_at
ESTs
93
1.84230
6.97694
5.13464
0.0053538023
1350165
AFFX-r2-Bs-lys-3_at
94
Plcb4
1.83790
8.07447
6.23657
0.00095211134
1359294
1441531_at
Phospholipase C beta 4 [Mus musculus], mRNA sequence
dendrite
microsome
nucleus
postsynaptic density
protein binding
signal transducer activity
signal transduction
smooth endoplasmic reticulum
95
Riok3
1.83441
8.07417
6.23976
8.5178578e-05
1343058
1460670_at
RIO kinase 3 (yeast) (Riok3), mRNA.
ATP binding
catalytic activity
kinase activity
nucleotide binding
protein amino acid phosphorylation
protein binding
protein serine/threonine kinase activity
transferase activity
96
1.82443
6.09079
4.26636
0.0028829094
1361161
1443630_at
ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus]
97
1.82391
6.42282
4.59891
0.00062609227
1350167
AFFX-r2-Bs-lys-M_at
98
1.81511
9.41977
7.60467
0.00062554271
1368145
1457356_at
Transcribed locus
99
Tnfrsf12a
1.81480
11.99156
10.17677
0.0038825844
1343706
1418572_x_at
tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), transcript variant 2, mRNA.
angiogenesis
apoptosis
cell adhesion
cell death
cell differentiation
cell surface
integral to membrane
membrane
multicellular organismal development
plasma membrane
positive regulation of axon extension
protein binding
receptor activity
ruffle
substrate-bound cell migration, cell attachment to substrate
100
1.81325
9.43564
7.62239
0.00078623965
1350180
AFFX-r2-Bs-thr-3_s_at
101
Nr4a3
1.81212
10.12148
8.30937
0.045176646
1357088
1438796_at
Nuclear receptor subfamily 4, group A, member 3 (Nr4a3), mRNA
adult behavior
DNA binding
inner ear morphogenesis
ligand-dependent nuclear receptor activity
mesoderm formation
metal ion binding
neuromuscular process controlling balance
nucleus
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
receptor activity
regulation of transcription, DNA-dependent
semicircular canal morphogenesis
sequence-specific DNA binding
steroid hormone receptor activity
transcription
transcription activator activity
transcription factor activity
vestibular reflex
zinc ion binding
102
Hectd2
1.80447
6.80361
4.99914
0.00088635164
1363593
1446224_at
HECT domain containing 2, mRNA (cDNA clone MGC:178371 IMAGE:9053363)
acid-amino acid ligase activity
intracellular
ligase activity
modification-dependent protein catabolic process
protein modification process
103
1.80375
7.23288
5.42914
0.002412252
1356438
1437584_at
Transcribed locus
104
1.80146
9.61537
7.81391
0.013929009
1350164
AFFX-r2-Bs-dap-M_at
105
Saa3
1.79562
9.32396
7.52833
0.0013118147
1348775
1450826_a_at
serum amyloid A 3 (Saa3), mRNA.
acute-phase response
extracellular region
high-density lipoprotein particle
106
1.79492
10.49182
8.69689
1.355471e-06
1366875
1455418_at
Transcribed locus
107
Slc39a14
1.78992
6.60321
4.81329
0.0006504949
1368500
1457770_at
Solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 3, mRNA
ferrous iron transmembrane transporter activity
integral to membrane
ion transport
iron ion transport
membrane
metal ion transmembrane transporter activity
metal ion transport
plasma membrane
transport
zinc ion binding
zinc ion transmembrane transporter activity
zinc ion transport
108
Sbno2
1.77839
7.12812
5.34974
0.0010020525
1371794
1443721_x_at
Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209)
macrophage activation during immune response
negative regulation of transcription, DNA-dependent
regulation of inflammatory response
regulation of transcription, DNA-dependent
transcription
transcription repressor activity
109
Mnda
1.77797
10.04845
8.27048
0.0009837498
1349242
1452349_x_at
myeloid cell nuclear differentiation antigen (Mnda), mRNA.
110
1.77496
8.13971
6.36475
0.0022182314
1364275
1446921_at
Transcribed locus
111
1.77100
9.23395
7.46295
0.001380804
1350152
AFFX-ThrX-3_at
B. subtilis GEN=thrB DB_XREF=gb:X04603.1 NOTE=SIF corresponding to nucleotides 1689-2151 of gb:X04603.1 DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively).
112
Mid1ip1
1.76591
12.52667
10.76076
0.0028229678
1328407
1416840_at
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) (Mid1ip1), mRNA.
cytoplasm
microtubule
microtubule cytoskeleton
negative regulation of microtubule depolymerization
nucleus
protein binding
protein C-terminus binding
113
1.75894
9.86718
8.10824
0.00022355676
1356892
1438429_at
Transcribed locus
114
Fkbp5
1.75811
9.84676
8.08865
0.00037990509
1338782
1448231_at
FK506 binding protein 5 (Fkbp5), mRNA.
binding
cytoplasm
isomerase activity
nucleus
peptidyl-prolyl cis-trans isomerase activity
protein binding
protein folding
115
1.75340
6.20506
4.45165
0.0031198216
1361128
1443593_at
Mus musculus 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430085A14 product:unknown EST, full insert sequence.
116
1.74284
9.46626
7.72343
0.010658023
1369874
1459238_at
ESTs
117
Sertad1
1.73635
10.16416
8.42782
0.0018649826
1328869
1417406_at
SERTA domain containing 1 (Sertad1), mRNA.
cytoplasm
negative regulation of cell growth
nucleus
positive regulation of transcription
protein binding
regulation of transcription, DNA-dependent
transcription
transcription activator activity
118
1.73482
8.65425
6.91943
3.5816648e-05
1369619
1458969_at
ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus]
119
Irf2bp2
1.73462
11.52201
9.78739
0.0122713
1354215
1433634_at
PREDICTED: interferon regulatory factor 2 binding protein 2, transcript variant 1 (Irf2bp2), mRNA.
negative regulation of transcription from RNA polymerase II promoter
nucleus
protein binding
transcription corepressor activity
120
1.73310
7.56480
5.83170
0.0091682908
1360637
1443069_at
Transcribed locus
121
1.72926
11.26309
9.53383
0.0084087856
1348119
1442025_a_at
Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus]
122
Ppp1r3c
1.72542
12.87700
11.15158
0.010975636
1334990
1425631_at
protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA.
carbohydrate metabolic process
glycogen biosynthetic process
glycogen metabolic process
protein binding
protein targeting
123
Jmjd1c
1.72501
9.75141
8.02640
0.0067268382
1335747
1426900_at
jumonji domain containing 1C (Jmjd1c), mRNA.
chromatin modification
iron ion binding
metal ion binding
nucleus
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
regulation of transcription, DNA-dependent
transcription
zinc ion binding
124
Cux1
1.72411
5.96558
4.24147
0.00047838982
1371720
1441956_s_at
CDNA fis, clone TRACH2005314,highly similar to Mus musculus mCASP (cux) mRNA
auditory receptor cell differentiation
chromatin binding
DNA binding
Golgi apparatus
integral to Golgi membrane
integral to membrane
intra-Golgi vesicle-mediated transport
lung development
membrane
multicellular organismal development
negative regulation of transcription from RNA polymerase II promoter
nucleus
regulation of transcription
regulation of transcription, DNA-dependent
sequence-specific DNA binding
transcription
transcription factor activity
transcription regulator activity
transcription repressor activity
transport
125
1.71480
6.82509
5.11030
0.00052754299
1370104
1459470_at
ESTs
126
Pfkfb4
1.71181
11.56894
9.85713
0.0015837865
1367712
1456888_at
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 splice isoform 7 (Pfkfb4) mRNA, complete cds, alternatively spliced
6-phosphofructo-2-kinase activity
ATP binding
catalytic activity
fructose 2,6-bisphosphate metabolic process
fructose metabolic process
fructose-2,6-bisphosphate 2-phosphatase activity
hydrolase activity
kinase activity
metabolic process
nucleotide binding
transferase activity
127
Dusp2
1.70838
8.48413
6.77574
0.0016123551
1340635
1450698_at
dual specificity phosphatase 2 (Dusp2), mRNA.
dephosphorylation
hydrolase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
mitogen-activated protein kinase binding
nucleus
phosphatase activity
phosphoprotein phosphatase activity
protein amino acid dephosphorylation
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
128
Tgfb2
1.70485
9.30628
7.60143
0.0011904982
1348802
1450922_a_at
transforming growth factor, beta 2 (Tgfb2), mRNA.
activation-induced cell death of T cells
axon
axon guidance
blood vessel development
blood vessel remodeling
cartilage condensation
cell growth
cell proliferation
cell soma
dopamine biosynthetic process
extracellular matrix organization
extracellular region
extracellular space
growth
growth factor activity
hair follicle development
hair follicle morphogenesis
heart development
hemopoiesis
induction of apoptosis
negative regulation of keratinocyte differentiation
neuron development
neuron fate commitment
pathway-restricted SMAD protein phosphorylation
positive regulation of cell cycle
protein binding
regulation of apoptosis
skeletal system development
somatic stem cell division
transforming growth factor beta receptor binding
129
1.70287
6.20716
4.50429
0.00044849522
1358927
1441129_at
Transcribed locus
130
5730409N24Rik
1.70075
7.21307
5.51233
0.0038343952
1351845
1430362_at
RIKEN cDNA 5730409N24 gene
131
1.69601
8.07290
6.37688
0.00020637066
1350145
AFFX-LysX-3_at
B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 1061-1343 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20).
132
Ankrd10
1.69069
9.00394
7.31326
0.0052767493
1343221
1416065_a_at
ankyrin repeat domain 10 (Ankrd10), mRNA.
133
Ccrn4l
1.69044
11.13428
9.44384
0.00083685428
1345554
1425837_a_at
CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA.
rhythmic process
134
AL024210
1.68839
8.44096
6.75257
4.8854375e-07
1338349
1438758_at
expressed sequence AL024210
135
1.68613
8.17169
6.48556
0.0043805128
1367751
1456927_at
Transcribed locus
136
1.68611
9.58700
7.90089
0.00073991668
1367261
1456139_at
Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130073E08 product:unknown EST, full insert sequence.
137
Tnfrsf12a
1.68554
12.10359
10.41805
0.0044841721
1329818
1418571_at
tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), transcript variant 2, mRNA.
angiogenesis
apoptosis
cell adhesion
cell death
cell differentiation
cell surface
integral to membrane
membrane
multicellular organismal development
plasma membrane
positive regulation of axon extension
protein binding
receptor activity
ruffle
substrate-bound cell migration, cell attachment to substrate
138
1.68215
7.24269
5.56054
0.00035870612
1368827
1458121_at
ESTs
139
1.67277
7.72990
6.05712
4.8389121e-07
1360495
1442916_at
Transcribed locus
140
1.67129
6.05819
4.38690
0.0005415698
1368397
1457637_at
Transcribed locus
141
1.66910
6.60260
4.93350
0.00046337603
1359231
1441467_at
Transcribed locus
142
Dusp5
1.66468
8.52804
6.86336
0.00088642324
1356231
1437199_at
Dual specificity phosphatase 5 (Dusp5), mRNA
hydrolase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
143
1.66276
6.86386
5.20110
0.0046176656
1358233
1440365_at
ESTs
144
1.65699
7.80144
6.14444
0.01172493
1363787
1446421_at
Transcribed locus
145
Malt1
1.65496
8.80054
7.14558
0.023163345
1367426
1456429_at
Mucosa associated lymphoid tissue lymphoma translocation gene 1, mRNA (cDNA clone MGC:124470 IMAGE:40048908)
apoptosis
B cell activation
B-1 B cell differentiation
cysteine-type endopeptidase activity
cytoplasm
cytosol
hydrolase activity
I-kappaB kinase/NF-kappaB cascade
innate immune response
modification-dependent protein catabolic process
nucleus
peptidase activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of T cell activation
protein binding
proteolysis
regulation of apoptosis
regulation of T cell receptor signaling pathway
response to fungus
response to molecule of bacterial origin
T cell proliferation
146
Mafb
1.65433
8.49461
6.84029
0.0010369686
1341364
1451715_at
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA.
brain segmentation
DNA binding
inner ear morphogenesis
nucleus
positive regulation of transcription from RNA polymerase II promoter
protein binding
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
respiratory gaseous exchange
rhombomere 5 development
rhombomere 6 development
segment specification
sequence-specific DNA binding
transcription
transcription factor activity
transcription factor complex
147
Mbd2
1.65218
5.97422
4.32204
0.0029259937
1359158
1441388_at
Methyl-CpG binding domain protein 2 (Mbd2), mRNA
cellular protein complex assembly
chromatin
chromatin binding
cytoplasm
DNA binding
heterochromatin
histone deacetylase complex
maternal behavior
methyl-CpG binding
mRNA binding
negative regulation of transcription from RNA polymerase II promoter
nucleolus
nucleus
positive regulation of Wnt receptor signaling pathway
regulation of cell proliferation
regulation of transcription, DNA-dependent
siRNA binding
transcription
148
1.64700
9.70499
8.05799
0.0074610457
1350144
AFFX-DapX-M_at
B. subtilis GEN=dapB, jojF DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2020-2580 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-
149
Ltbp3
1.64385
6.20267
4.55882
0.0020038048
1356563
1437833_at
Latent transforming growth factor beta binding protein 3 (Ltbp3), mRNA
binding
calcium ion binding
extracellular region
growth factor binding
proteinaceous extracellular matrix
skeletal system development
transforming growth factor beta receptor signaling pathway
transforming growth factor beta receptor signaling pathway
150
Per2
1.64374
8.28708
6.64333
3.5002267e-05
1329035
1417602_at
Period homolog 2 (Drosophila) (Per2), mRNA
circadian rhythm
cytoplasm
negative regulation of specific transcription from RNA polymerase II promoter
nucleus
protein binding
regulation of transcription, DNA-dependent
rhythmic process
signal transducer activity
signal transduction
transcription
151
Fmo2
1.64270
8.56799
6.92528
0.0020098326
1344723
1422905_s_at
flavin containing monooxygenase 2 (Fmo2), mRNA.
endoplasmic reticulum
FAD binding
flavin-containing monooxygenase activity
integral to membrane
intrinsic to endoplasmic reticulum membrane
magnesium ion binding
membrane
microsome
monooxygenase activity
NADP or NADPH binding
oxidation reduction
oxidoreductase activity
oxygen and reactive oxygen species metabolic process
152
1.63778
7.86148
6.22370
0.0058168562
1356390
1437493_at
Transcribed locus
153
1.63376
6.90599
5.27222
0.0020763563
1369248
1458588_at
Unknown
154
A130040M12Rik
1.61960
10.61152
8.99192
0.018281371
1349404
1453238_s_at
RIKEN cDNA A130040M12 gene (A130040M12Rik), non-coding RNA.
155
Lonrf3
1.61845
7.46662
5.84817
8.5159425e-05
1355677
1436200_at
LON peptidase N-terminal domain and ring finger 3, mRNA (cDNA clone MGC:155927 IMAGE:40129613)
ATP-dependent peptidase activity
binding
metal ion binding
protein binding
proteolysis
zinc ion binding
156
Zfp36
1.61759
10.40501
8.78742
3.5912455e-05
1349296
1452519_a_at
zinc finger protein 36 (Zfp36), mRNA.
AU-rich element binding
cytoplasm
cytosol
cytosol
DNA binding
metal ion binding
mRNA binding
mRNA binding
mRNA catabolic process
negative regulation of inflammatory response
negative regulation of myeloid cell differentiation
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
nucleic acid binding
nucleus
protein kinase cascade
regulation of mRNA stability
RNA destabilization
zinc ion binding
157
Mtss1
1.61376
6.53232
4.91855
0.012829803
1363652
1446284_at
Metastasis suppressor 1, mRNA (cDNA clone IMAGE:5343395)
actin binding
actin filament organization
actin filament polymerization
cytoplasm
cytoskeletal adaptor activity
cytoskeleton
filopodium assembly
muscle organ development
nervous system development
SH3 domain binding
signal transduction
158
Acer2
1.61246
9.15108
7.53861
0.00032791091
1341119
1451355_at
alkaline ceramidase 2 (Acer2), mRNA.
ceramidase activity
ceramide metabolic process
endoplasmic reticulum membrane
Golgi apparatus
Golgi membrane
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
integral to membrane
lipid metabolic process
membrane
159
1.61058
9.13168
7.52110
0.00025969455
1338484
1442026_at
Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus]
160
Gadd45g
1.60416
10.93832
9.33416
0.019706689
1349481
1453851_a_at
growth arrest and DNA-damage-inducible 45 gamma (Gadd45g), mRNA.
activation of MAPKK activity
apoptosis
cell differentiation
interferon-gamma biosynthetic process
multicellular organismal development
negative regulation of protein kinase activity
nucleus
protein binding
regulation of cell cycle
T-helper 1 cell differentiation
161
1.60318
6.68224
5.07905
0.00020982383
1369156
1458496_at
Transcribed locus
162
5430437C10Rik
1.59321
8.09606
6.50285
0.019764328
1365603
1453512_at
RIKEN cDNA 5430437C10 gene
163
1.58092
6.29662
4.71569
0.0017987956
1368349
1457575_at
Transcribed locus
164
1.58049
6.89868
5.31819
0.00059207034
1350170
AFFX-r2-Bs-phe-M_at
165
1.57944
6.98801
5.40857
0.044602156
1370262
1459635_at
ESTs
166
Gpr116
1.57535
8.51118
6.93583
0.020527676
1358101
1440225_at
G protein-coupled receptor 116 (Gpr116), mRNA
integral to membrane
membrane
plasma membrane
167
Slc2a1
1.57332
9.02289
7.44957
0.0013319039
1347098
1434773_a_at
solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA.
basolateral plasma membrane
carbohydrate transport
cytoplasm
glucose transmembrane transporter activity
glucose transport
integral to membrane
intracellular
membrane
plasma membrane
protein binding
substrate-specific transmembrane transporter activity
sugar:hydrogen symporter activity
transmembrane transport
transport
transporter activity
168
Srxn1
1.55851
8.93408
7.37557
0.00065296593
1334833
1425351_at
sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA.
antioxidant activity
ATP binding
cytoplasm
cytosol
magnesium ion binding
nucleotide binding
oxidation reduction
oxidoreductase activity
response to oxidative stress
sulfiredoxin activity
169
1.54915
7.91103
6.36188
0.00051105108
1369075
1458409_at
ESTs
170
Midn
1.54415
9.47634
7.93219
0.00041544803
1339561
1449188_at
midnolin (Midn), mRNA.
nucleolus
nucleus
171
Uck2
1.53938
9.42806
7.88868
0.0011224648
1371475
1439740_s_at
Uridine-cytidine kinase 2, mRNA (cDNA clone IMAGE:3493906)
ATP binding
kinase activity
metabolic process
nucleotide binding
phosphotransferase activity, alcohol group as acceptor
transferase activity
uridine kinase activity
172
1.53916
8.38857
6.84941
0.0089168869
1350168
AFFX-r2-Bs-phe-3_at
173
LOC100039464
1.53833
10.61341
9.07508
0.0057368039
1341848
1452418_at
PREDICTED: similar to gag protein, transcript variant 1 (LOC100039464), mRNA.
174
Txnrd1
1.53812
7.93573
6.39760
0.0060295051
1360727
1443159_at
Thioredoxin reductase 1, mRNA (cDNA clone MGC:46868 IMAGE:5059831)
cell proliferation
cell redox homeostasis
cytoplasm
cytosol
FAD binding
gastrulation
mesoderm formation
NADP or NADPH binding
nucleus
oxidation reduction
oxidoreductase activity
selenium binding
thioredoxin-disulfide reductase activity
175
1.53139
6.61482
5.08343
1.7754817e-06
1362606
1445200_at
ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus]
176
Csf2rb
1.53082
8.33246
6.80164
0.021983894
1367030
1455660_at
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), mRNA.
cytokine receptor activity
cytokine-mediated signaling pathway
integral to membrane
membrane
protein binding
receptor activity
177
Runx1
1.52919
6.55224
5.02305
0.01327002
1332966
1422865_at
runt related transcription factor 1 (Runx1), transcript variant 2, mRNA.
ATP binding
behavioral response to pain
central nervous system development
definitive hemopoiesis
DNA binding
embryonic hemopoiesis
in utero embryonic development
liver development
neuron development
neuron differentiation
nucleus
positive regulation of angiogenesis
protein binding
regulation of transcription, DNA-dependent
response to retinoic acid
skeletal system development
transcription
transcription factor activity
178
1.52903
6.58665
5.05762
3.5381755e-05
1370236
1459609_at
Unknown
179
Adamts1
1.52535
10.47602
8.95068
0.0041427391
1340651
1450716_at
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), mRNA.
basement membrane
cytoplasmic vesicle
extracellular matrix
extracellular region
heart trabecula formation
heparin binding
hydrolase activity
kidney development
metal ion binding
metalloendopeptidase activity
metalloendopeptidase activity
metalloendopeptidase activity
metallopeptidase activity
negative regulation of angiogenesis
ovulation from ovarian follicle
peptidase activity
protein binding
proteinaceous extracellular matrix
proteolysis
zinc ion binding
180
Arid5b
1.52450
8.35278
6.82828
0.00079712253
1359813
1442176_at
AT rich interactive domain 5B (MRF1-like) (Arid5b), mRNA.
DNA binding
face morphogenesis
fibroblast migration
intracellular
kidney development
multicellular organism growth
muscle organ morphogenesis
nitrogen compound metabolic process
nucleus
palate development
platelet-derived growth factor receptor signaling pathway
post-embryonic development
regulation of transcription, DNA-dependent
skeletal system morphogenesis
transcription
181
1.51776
6.61647
5.09870
0.00058697899
1365738
1453698_at
Transcribed locus
182
Adh1
1.51555
11.09286
9.57731
0.0024946744
1327922
1416225_at
alcohol dehydrogenase 1 (class I) (Adh1), mRNA.
alcohol dehydrogenase (NAD) activity
alcohol dehydrogenase (NAD) activity
behavioral response to ethanol
cytoplasm
ethanol catabolic process
ethanol catabolic process
intracellular
metal ion binding
mitochondrion
oxidation reduction
oxidoreductase activity
protein homodimerization activity
response to retinoic acid
response to steroid hormone stimulus
response to testosterone stimulus
retinoic acid metabolic process
retinoic acid metabolic process
retinoid metabolic process
retinol metabolic process
retinol metabolic process
zinc ion binding
183
1.50847
5.73931
4.23083
0.0012810554
1369860
1459224_at
Mus musculus 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732469E12 product:unclassifiable, full insert sequence.
184
Nfkbiz
1.50495
6.92763
5.42269
8.9879026e-05
1328931
1417483_at
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 3, mRNA.
inflammatory response
nucleus
regulation of transcription, DNA-dependent
transcription
185
Prom1
1.50409
7.71644
6.21235
0.00042654615
1343918
1419700_a_at
prominin 1 (Prom1), mRNA.
apical plasma membrane
brush border
cell projection
cell surface
extracellular space
integral to membrane
integral to plasma membrane
membrane
microvillus
plasma membrane
stereocilium
186
AI607873
1.50069
6.21488
4.71419
8.0364161e-05
1367851
1457035_at
PREDICTED: expressed sequence AI607873 (AI607873), mRNA.
187
Nrip1
1.50005
10.83721
9.33716
0.034586344
1329744
1418469_at
Receptor interacting protein 140
histone deacetylase binding
histone deacetylase complex
lipid storage
negative regulation of transcription from RNA polymerase II promoter
nucleus
ovarian follicle rupture
ovulation
protein binding
receptor activity
receptor binding
regulation of transcription, DNA-dependent
retinoid X receptor binding
transcription
transcription corepressor activity
188
Cdc14a
1.49346
7.31188
5.81841
0.0035887306
1356093
1436913_at
CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), mRNA.
cell cycle
cell division
dephosphorylation
hydrolase activity
nucleus
phosphatase activity
phosphoprotein phosphatase activity
protein amino acid dephosphorylation
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
189
Errfi1
1.49298
10.11080
8.61782
0.00065326466
1327847
1416129_at
ERBB receptor feedback inhibitor 1 (Errfi1), mRNA.
cytoplasm
cytosol
protein binding
receptor activity
stress-activated protein kinase signaling pathway
190
1.49008
10.53126
9.04117
0.0032792488
1351474
1429900_at
Transcribed locus
191
Airn
1.48906
8.69993
7.21087
0.00019769304
1341319
1451634_at
antisense Igf2r RNA (Airn), transcript variant 1, non-coding RNA.
genetic imprinting
192
Osmr
1.48454
9.14866
7.66411
4.3928093e-06
1329909
1418674_at
oncostatin M receptor (Osmr), mRNA.
cell surface receptor linked signal transduction
cytokine receptor activity
integral to membrane
integral to plasma membrane
membrane
oncostatin-M receptor activity
receptor activity
193
Tnik
1.48143
8.47464
6.99322
0.0091245899
1351449
1429870_at
TRAF2 and NCK interacting kinase, mRNA (cDNA clone MGC:183916 IMAGE:9087916)
ATP binding
kinase activity
nucleotide binding
protein amino acid phosphorylation
protein kinase activity
protein serine/threonine kinase activity
small GTPase regulator activity
transferase activity
194
Epm2aip1
1.47764
9.52496
8.04732
7.8144053e-06
1354463
1434106_at
EPM2A (laforin) interacting protein 1 (Epm2aip1), mRNA.
endoplasmic reticulum
195
1.47736
7.09502
5.61766
0.00097202554
1362068
1444645_at
Transcribed locus
196
Slc25a12
1.47149
7.68226
6.21076
0.001183738
1361920
1444489_at
Solute carrier family 25 (mitochondrial carrier, Aralar), member 12, mRNA (cDNA clone MGC:67718 IMAGE:6311836)
binding
calcium ion binding
integral to membrane
malate-aspartate shuttle
membrane
mitochondrial inner membrane
mitochondrial inner membrane
mitochondrion
mitochondrion
transport
transporter activity
197
1.46944
6.17005
4.70061
0.0046491776
1350166
AFFX-r2-Bs-lys-5_at
198
Cdc14a
1.46728
7.37802
5.91075
0.00036639432
1360752
1443184_at
CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), mRNA
cell cycle
cell division
dephosphorylation
hydrolase activity
nucleus
phosphatase activity
phosphoprotein phosphatase activity
protein amino acid dephosphorylation
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
199
Aldh2
1.46709
8.01096
6.54387
0.0029925385
1356345
1437410_at
Aldehyde dehydrogenase 2, mitochondrial, mRNA (cDNA clone MGC:6764 IMAGE:3600875)
aldehyde dehydrogenase (NAD) activity
metabolic process
mitochondrion
oxidation reduction
oxidoreductase activity
200
Cdkn1a
1.46084
9.52793
8.06709
0.0019270313
1344415
1421679_a_at
cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA.
cell cycle
cell cycle arrest
cyclin binding
cyclin-dependent protein kinase holoenzyme complex
cyclin-dependent protein kinase inhibitor activity
cytoplasm
cytosol
kinase activity
metal ion binding
negative regulation of apoptosis
negative regulation of cell proliferation
negative regulation of cyclin-dependent protein kinase activity
nucleus
positive regulation of B cell proliferation
positive regulation of programmed cell death
protein binding
protein kinase inhibitor activity
regulation of cell cycle
response to DNA damage stimulus
response to UV
zinc ion binding
201
Fam107a
1.46012
5.71169
4.25157
0.000847205
1355485
1435918_at
Family with sequence similarity 107, member A (Fam107a), mRNA
202
Arrdc2
1.45924
9.47776
8.01852
0.016776483
1350443
1428352_at
arrestin domain containing 2 (Arrdc2), mRNA.
203
1.45470
10.25804
8.80334
0.0043486049
1369044
1458376_at
Transcribed locus
204
Rabif
1.45033
9.67815
8.22783
9.6337626e-07
1343970
1419927_s_at
RAB interacting factor (Rabif), mRNA.
guanyl-nucleotide exchange factor activity
metal ion binding
protein transport
small GTPase mediated signal transduction
transport
zinc ion binding
205
Etl4
1.44946
7.71027
6.26082
0.0078513257
1342688
1457147_at
Enhancer trap locus 4, mRNA (cDNA clone IMAGE:4988846)
cytoplasm
embryonic skeletal system development
multicellular organismal development
206
1200015M12Rik
1.44715
10.02653
8.57938
0.0097103876
1347155
1435137_s_at
RIKEN cDNA 1200015M12 gene
207
1.44458
6.85076
5.40618
0.0030787549
1359142
1441372_at
Transcribed locus
208
1.44244
9.29974
7.85730
1.8289658e-06
1367413
1456413_at
Transcribed locus
209
Pik3r1
1.43975
8.00608
6.56633
0.0061270902
1334929
1425514_at
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 1, mRNA.
1-phosphatidylinositol-3-kinase activity
B cell differentiation
cytoplasm
cytosol
insulin receptor substrate binding
intracellular
kinase activity
membrane
negative regulation of apoptosis
negative regulation of apoptosis
negative regulation of cell-matrix adhesion
negative regulation of osteoclast differentiation
phosphoinositide 3-kinase complex
phosphoinositide 3-kinase regulator activity
positive regulation of cell migration
protein amino acid phosphorylation
protein binding
signal transduction
210
1.43749
8.67488
7.23739
0.0022710252
1360856
1443289_at
Transcribed locus
211
1.43101
7.39884
5.96784
0.00051015016
1361052
1443511_at
Transcribed locus
212
Tgm2
1.42758
11.96745
10.53987
0.00060160607
1347528
1437277_x_at
Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943)
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
acyltransferase activity
branching involved in salivary gland morphogenesis
calcium ion binding
cytoplasm
cytosol
G-protein coupled receptor protein signaling pathway
GTP binding
membrane
metal ion binding
peptide cross-linking
positive regulation of cell adhesion
protein-glutamine gamma-glutamyltransferase activity
proteinaceous extracellular matrix
salivary gland cavitation
transferase activity
213
1.42379
6.15449
4.73071
0.001356331
1369097
1458432_at
Transcribed locus
214
1.42315
6.06594
4.64279
0.021291402
1359145
1441375_at
ESTs
215
1.42294
6.37161
4.94868
0.0085988014
1360905
1443341_at
ESTs
216
1.42087
8.75510
7.33423
0.0027521772
1359623
1441976_at
Transcribed locus
217
LOC100039204
1.41943
11.17432
9.75490
0.003715644
1345101
1424607_a_at
PREDICTED: hypothetical protein LOC100039204 (LOC100039204), misc RNA.
218
Tgm2
1.40721
11.42765
10.02044
2.5780386e-06
1346897
1433428_x_at
Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943)
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
acyltransferase activity
branching involved in salivary gland morphogenesis
calcium ion binding
cytoplasm
cytosol
G-protein coupled receptor protein signaling pathway
GTP binding
membrane
metal ion binding
peptide cross-linking
positive regulation of cell adhesion
protein-glutamine gamma-glutamyltransferase activity
proteinaceous extracellular matrix
salivary gland cavitation
transferase activity
219
Spag9
1.39750
6.81671
5.41922
0.00020678594
1356486
1437676_at
JNK-associated leucine-zipper protein
activation of MAPK activity
cytoplasm
JUN kinase binding
kinesin binding
protein homooligomerization
220
1.39041
8.79233
7.40191
0.027798395
1370792
1420098_s_at
Transcribed locus
221
Tgm2
1.39012
11.63692
10.24680
0.00011318412
1343507
1417500_a_at
transglutaminase 2, C polypeptide (Tgm2), mRNA.
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
acyltransferase activity
branching involved in salivary gland morphogenesis
calcium ion binding
cytoplasm
cytosol
G-protein coupled receptor protein signaling pathway
GTP binding
membrane
metal ion binding
peptide cross-linking
positive regulation of cell adhesion
protein-glutamine gamma-glutamyltransferase activity
proteinaceous extracellular matrix
salivary gland cavitation
transferase activity
222
Ptpn1
1.38966
10.49743
9.10777
0.0015519966
1343431
1417068_a_at
protein tyrosine phosphatase, non-receptor type 1 (Ptpn1), mRNA.
dephosphorylation
endoplasmic reticulum
hydrolase activity
insulin receptor signaling pathway
membrane
phosphatase activity
phosphoprotein phosphatase activity
protein amino acid dephosphorylation
protein tyrosine phosphatase activity
receptor activity
223
Slc43a3
1.38963
9.50328
8.11365
0.0010443655
1332904
1422788_at
solute carrier family 43, member 3 (Slc43a3), mRNA.
integral to membrane
membrane
224
Flnc
1.38841
12.41507
11.02665
0.0061461756
1339463
1449073_at
filamin C, gamma (Flnc), mRNA.
actin binding
actin cytoskeleton
actin filament-based process
cytoplasm
cytoskeleton
membrane
muscle fiber development
225
Fibin
1.38821
9.72896
8.34074
0.0042311131
1330481
1419376_at
fin bud initiation factor homolog (zebrafish) (Fibin), mRNA.
extracellular region
Golgi apparatus
226
1.38737
11.17880
9.79142
0.0026140747
1345103
1424609_a_at
Mus musculus, Similar to RIKEN cDNA 1700066C05 gene, clone MGC:28125 IMAGE:3980327, mRNA, complete cds
227
Kdm6b
1.38708
10.28403
8.89695
0.0024217882
1367516
1456610_at
KDM1 lysine (K)-specific demethylase 6B (Kdm6b), mRNA.
chromatin modification
histone demethylation
inflammatory response
iron ion binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
negative regulation of transcription from RNA polymerase II promoter
nucleus
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
sequence-specific DNA binding
228
Socs2
1.38183
7.99067
6.60884
0.030192901
1343687
1418507_s_at
Suppressor of cytokine signaling 2 (Socs2), mRNA
growth hormone receptor binding
intracellular signaling cascade
lactation
lactation
mammary gland alveolus development
mammary gland alveolus development
modification-dependent protein catabolic process
negative regulation of JAK-STAT cascade
negative regulation of multicellular organism growth
negative regulation of multicellular organism growth
negative regulation of signal transduction
positive regulation of neuron differentiation
regulation of growth
regulation of multicellular organism growth
229
1.38158
8.13861
6.75703
0.002965989
1353584
1432850_at
Transcribed locus
230
Mnda
1.37995
8.26724
6.88729
0.025783706
1349241
1452348_s_at
myeloid cell nuclear differentiation antigen (Mnda), mRNA.
231
Ip6k3
1.37684
8.87152
7.49468
0.00051818212
1361044
1443503_at
Inositol hexaphosphate kinase 3, mRNA (cDNA clone MGC:176224 IMAGE:9055875)
232
Glul
1.37664
12.75465
11.37801
0.00048649192
1345787
1426236_a_at
glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA.
ATP binding
catalytic activity
cytoplasm
glutamate-ammonia ligase activity
glutamine biosynthetic process
intracellular
ligase activity
mitochondrion
nitrogen compound metabolic process
nucleotide binding
response to glucose stimulus
233
Slc39a14
1.37476
9.08922
7.71446
0.014789219
1335858
1427035_at
solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 2, mRNA.
ferrous iron transmembrane transporter activity
integral to membrane
ion transport
iron ion transport
membrane
metal ion transmembrane transporter activity
metal ion transport
plasma membrane
transport
zinc ion binding
zinc ion transmembrane transporter activity
zinc ion transport
234
1.37059
5.72056
4.34997
0.0012728203
1360461
1442880_at
Transcribed locus
235
Cxcl2
1.36945
5.41681
4.04735
0.015315876
1340126
1449984_at
Chemokine (C-X-C motif) ligand 2 (Cxcl2), mRNA
chemokine activity
chemotaxis
cytokine activity
extracellular region
extracellular space
immune response
inflammatory response
236
Atp8a1
1.36906
6.07465
4.70559
0.031272501
1361787
1444355_at
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (Atp8a1), transcript variant 2, mRNA
ATP binding
ATP biosynthetic process
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
catalytic activity
cytoplasmic vesicle
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
integral to membrane
magnesium ion binding
membrane
metabolic process
metal ion binding
nucleotide binding
phospholipid transport
phospholipid-translocating ATPase activity
237
Thbd
1.36432
10.73528
9.37096
0.011099108
1339017
1448529_at
thrombomodulin (Thbd), mRNA.
binding
blood coagulation
calcium ion binding
embryonic development
female pregnancy
integral to membrane
membrane
negative regulation of coagulation
plasma membrane
receptor activity
238
Cxcl1
1.35735
5.79985
4.44250
0.0028945968
1330349
1419209_at
chemokine (C-X-C motif) ligand 1 (Cxcl1), mRNA.
chemokine activity
cytokine activity
extracellular region
extracellular space
growth factor activity
immune response
inflammatory response
239
Flt1
1.35610
10.32163
8.96553
0.00080735403
1341390
1451756_at
FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921)
angiogenesis
ATP binding
cell differentiation
cell migration
identical protein binding
integral to membrane
kinase activity
membrane
multicellular organismal development
nucleotide binding
patterning of blood vessels
protein amino acid phosphorylation
protein kinase activity
protein tyrosine kinase activity
receptor activity
transferase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
vascular endothelial growth factor receptor activity
vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway
240
1.35439
9.55976
8.20537
0.0052177661
1368255
1457477_at
Transcribed locus
241
Csf2rb2
1.34928
6.98329
5.63401
2.3441936e-05
1339699
1449360_at
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) (Csf2rb2), mRNA.
cytokine receptor activity
cytokine-mediated signaling pathway
integral to membrane
membrane
receptor activity
242
Mast4
1.34912
8.49139
7.14227
0.00083664117
1360008
1442382_at
MKIAA0303 protein
ATP binding
cytoplasm
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
protein amino acid phosphorylation
protein binding
protein kinase activity
protein serine/threonine kinase activity
transferase activity
243
Tmpo
1.34836
8.75966
7.41130
2.971282e-05
1350820
1428976_at
thymopoietin (Tmpo), transcript variant 1, mRNA.
chromatin
chromosome
DNA binding
integral to membrane
membrane
nuclear envelope
nucleus
protein binding
protein binding
regulation of transcription
244
Sgms2
1.34814
7.45048
6.10235
0.010701632
1350856
1429029_at
Sphingomyelin synthase 2 (Sgms2), mRNA
ceramide cholinephosphotransferase activity
Golgi apparatus
integral to Golgi membrane
integral to membrane
integral to plasma membrane
kinase activity
lipid metabolic process
membrane
plasma membrane
sphingolipid metabolic process
sphingomyelin biosynthetic process
sphingomyelin synthase activity
transferase activity
245
1.34188
5.42791
4.08604
0.0025797685
1364442
1447096_at
Transcribed locus
246
1.34150
8.42676
7.08527
0.00069192638
1369275
1458616_at
Transcribed locus
247
Nedd4l
1.33531
8.47127
7.13596
0.00024148154
1368162
1457374_at
Neural precursor cell expressed, developmentally down-regulated gene 4-like, mRNA (cDNA clone MGC:49433 IMAGE:3157137)
acid-amino acid ligase activity
cytoplasm
intracellular
ligase activity
modification-dependent protein catabolic process
negative regulation of sodium ion transport
negative regulation of sodium ion transport
protein binding
protein modification process
sodium channel inhibitor activity
248
1.33302
5.99828
4.66526
0.00010791921
1358021
1440111_at
ESTs
249
1.33254
6.45177
5.11923
0.0079745297
1370101
1459467_at
ESTs
250
Tubb6
1.33088
9.88533
8.55445
0.015278896
1328081
1416431_at
tubulin, beta 6 (Tubb6), mRNA.
GTP binding
GTPase activity
microtubule
microtubule-based movement
microtubule-based process
nucleotide binding
protein complex
protein polymerization
structural molecule activity
251
2810474O19Rik
1.32634
8.49414
7.16780
0.038096902
1338102
1437110_at
RIKEN cDNA 2810474O19 gene (2810474O19Rik), mRNA.
252
Bach1
1.32499
7.75779
6.43280
0.021986489
1339662
1449311_at
BTB and CNC homology 1 (Bach1), mRNA
DNA binding
nucleus
protein binding
protein dimerization activity
regulation of transcription, DNA-dependent
sequence-specific DNA binding
transcription
transcription factor activity
253
1.32497
8.14595
6.82098
0.0035536382
1356556
1437821_at
Mus musculus 7 days embryo whole body cDNA, RIKEN full-length enriched library, clone:C430005H19 product:unknown EST, full insert sequence.
254
Hectd1
1.32433
10.74011
9.41577
0.010061013
1356671
1438039_at
HECT domain containing 1 (Hectd1), mRNA.
ligase activity
modification-dependent protein catabolic process
neural tube closure
255
Ankrd10
1.32012
10.02378
8.70365
0.00024973383
1338758
1448199_at
ankyrin repeat domain 10 (Ankrd10), mRNA.
256
Ldlr
1.31303
8.69005
7.37702
0.0030560901
1332178
1421821_at
low density lipoprotein receptor (Ldlr), mRNA.
calcium ion binding
cholesterol homeostasis
cholesterol homeostasis
cholesterol metabolic process
cholesterol transport
coated pit
endocytosis
endosome
integral to membrane
lipid metabolic process
lipid transport
lipoprotein catabolic process
lipoprotein catabolic process
lipoprotein metabolic process
low-density lipoprotein binding
low-density lipoprotein particle
low-density lipoprotein receptor activity
low-density lipoprotein receptor activity
membrane
protein binding
receptor activity
steroid metabolic process
transport
very-low-density lipoprotein receptor activity
257
1.30942
6.57576
5.26634
0.011848648
1364301
1446947_at
Unknown
258
1.30904
8.17836
6.86932
0.0374361
1367839
1457022_at
ESTs, Weakly similar to POL2_MOUSE Retrovirus-related POL polyprotein [Contains: Reverse transcriptase ; Endonuclease] [M.musculus]
259
Smad1
1.30852
9.45211
8.14359
0.0026032491
1338766
1448208_at
MAD homolog 1 (Drosophila) (Smad1), mRNA.
BMP signaling pathway
BMP signaling pathway
BMP signaling pathway
cytoplasm
gamete generation
hindbrain development
homeostatic process
inflammatory response
intracellular
MAPKKK cascade
mesodermal cell fate commitment
midbrain development
negative regulation of cell proliferation
nucleus
osteoblast fate commitment
positive regulation of gene expression
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
protein binding
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
RNA polymerase II transcription factor activity
transcription
transcription factor activity
transcription factor complex
transforming growth factor beta receptor signaling pathway
260
1.30827
9.43129
8.12302
0.01437126
1363692
1446324_at
Transcribed locus
261
Myh9
1.30434
7.02021
5.71587
0.0034014386
1358568
1440708_at
Myosin, heavy polypeptide 9, non-muscle, mRNA (cDNA clone IMAGE:4913872)
actin binding
actin filament binding
actin filament-based movement
actin-dependent ATPase activity
ADP binding
ATP binding
calmodulin binding
cell adhesion
cell cortex
cell morphogenesis involved in differentiation
cell motion
cell-cell adherens junction
cell-cell adhesion
cortical cytoskeleton
cytoplasm
establishment of meiotic spindle localization
establishment of T cell polarity
immunological synapse
immunological synapse
in utero embryonic development
meiotic metaphase I
meiotic spindle organization
microfilament motor activity
motor activity
myoblast fusion
myosin complex
neuromuscular junction
nucleotide binding
plasma membrane
plasma membrane
protein binding
regulation of cell shape
spindle
stress fiber
stress fiber
uropod
uropod
uropod organization
262
Smad1
1.30367
8.46654
7.16287
8.3593405e-05
1327807
1416081_at
MAD homolog 1 (Drosophila) (Smad1), mRNA.
BMP signaling pathway
BMP signaling pathway
BMP signaling pathway
cytoplasm
gamete generation
hindbrain development
homeostatic process
inflammatory response
intracellular
MAPKKK cascade
mesodermal cell fate commitment
midbrain development
negative regulation of cell proliferation
nucleus
osteoblast fate commitment
positive regulation of gene expression
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
protein binding
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
RNA polymerase II transcription factor activity
transcription
transcription factor activity
transcription factor complex
transforming growth factor beta receptor signaling pathway
263
1.30277
7.37517
6.07240
1.181016e-05
1359818
1442181_at
ESTs
264
1.30258
7.60960
6.30702
0.01340227
1356853
1438352_at
Transcribed locus
265
1.30152
5.07150
3.76999
0.0002743909
1367580
1456717_at
ESTs
266
Serpine1
1.29643
7.90619
6.60976
0.0030702464
1330303
1419149_at
serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1), mRNA.
endopeptidase inhibitor activity
extracellular region
protein binding
regulation of angiogenesis
regulation of cell proliferation
serine-type endopeptidase activity
serine-type endopeptidase inhibitor activity
267
1.29541
7.69810
6.40268
0.011138922
1354998
1435125_at
Transcribed locus
268
Flnc
1.29136
13.13471
11.84335
0.0036011473
1372102
1447812_x_at
Strain C3H filamin
actin binding
actin cytoskeleton
actin filament-based process
cytoplasm
cytoskeleton
membrane
muscle fiber development
269
Ankrd10
1.28891
9.02743
7.73852
0.0019181976
1351042
1429304_at
Ankyrin repeat domain 10 (Ankrd10), mRNA
270
Glul
1.28695
11.99883
10.71188
0.00099112834
1345786
1426235_a_at
glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA.
ATP binding
catalytic activity
cytoplasm
glutamate-ammonia ligase activity
glutamine biosynthetic process
intracellular
ligase activity
mitochondrion
nitrogen compound metabolic process
nucleotide binding
response to glucose stimulus
271
1.28552
7.95202
6.66650
0.00041733377
1356243
1437219_at
Transcribed locus
272
Slc25a30
1.28493
9.43622
8.15129
0.0047084115
1331467
1420836_at
Solute carrier family 25, member 30, mRNA (cDNA clone MGC:31367 IMAGE:4238839)
binding
integral to membrane
membrane
mitochondrial inner membrane
mitochondrion
transport
transporter activity
273
D17H6S56E-5
1.28409
7.10034
5.81626
0.012388073
1329204
1417821_at
DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942)
viral envelope
274
Mcf2l
1.28360
9.88030
8.59670
1.6576166e-05
1354476
1434140_at
Guanine nucleotide exchange factor OSTIII mRNA, complete cds, alternatively spliced
cytoplasm
guanyl-nucleotide exchange factor activity
intracellular
intracellular signaling cascade
lamellipodium
membrane
phosphatidylinositol binding
plasma membrane
protein binding
regulation of Rho protein signal transduction
Rho guanyl-nucleotide exchange factor activity
Rho protein signal transduction
275
1.28350
8.82167
7.53818
0.00013052401
1371306
1437073_x_at
Transcribed locus
276
Pde4b
1.28336
11.46034
10.17697
0.0066597163
1332654
1422473_at
Phosphodiesterase 4B, cAMP specific, mRNA (cDNA clone IMAGE:5354427)
3',5'-cyclic-AMP phosphodiesterase activity
smooth muscle contraction
277
Tgm2
1.27878
9.63900
8.36022
0.00028478051
1349776
1455900_x_at
transglutaminase 2, C polypeptide
278
Rcan1
1.27813
11.73207
10.45394
0.0092251192
1343341
1416600_a_at
Regulator of calcineurin 1, mRNA (cDNA clone MGC:19348 IMAGE:4236038)
calcium-mediated signaling
cytoplasm
nucleus
regulation of phosphoprotein phosphatase activity
skeletal muscle fiber development
279
1.27746
6.53702
5.25956
0.0015115138
1364419
1447071_at
Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230007B16 product:unknown EST, full insert sequence.
280
Tgfb2
1.27331
8.38180
7.10850
0.00035072531
1340805
1450923_at
transforming growth factor, beta 2 (Tgfb2), mRNA.
activation-induced cell death of T cells
axon
axon guidance
blood vessel development
blood vessel remodeling
cartilage condensation
cell growth
cell proliferation
cell soma
dopamine biosynthetic process
extracellular matrix organization
extracellular region
extracellular space
growth
growth factor activity
hair follicle development
hair follicle morphogenesis
heart development
hemopoiesis
induction of apoptosis
negative regulation of keratinocyte differentiation
neuron development
neuron fate commitment
pathway-restricted SMAD protein phosphorylation
positive regulation of cell cycle
protein binding
regulation of apoptosis
skeletal system development
somatic stem cell division
transforming growth factor beta receptor binding
281
Fzd4
1.27268
10.45927
9.18659
0.022428861
1330421
1419301_at
frizzled homolog 4 (Drosophila) (Fzd4), mRNA.
cell surface receptor linked signal transduction
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
integral to membrane
membrane
multicellular organismal development
non-G-protein coupled 7TM receptor activity
protein binding
receptor activity
signal transducer activity
signal transduction
transmembrane receptor activity
Wnt receptor signaling pathway
282
1.27002
7.03094
5.76092
0.0003348494
1363294
1445919_at
ESTs
283
Smad1
1.26753
8.77899
7.51146
0.0097965933
1372645
1459843_s_at
MAD homolog 1 (Drosophila) (Smad1), mRNA
BMP signaling pathway
BMP signaling pathway
BMP signaling pathway
cytoplasm
gamete generation
hindbrain development
homeostatic process
inflammatory response
intracellular
MAPKKK cascade
mesodermal cell fate commitment
midbrain development
negative regulation of cell proliferation
nucleus
osteoblast fate commitment
positive regulation of gene expression
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
protein binding
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
RNA polymerase II transcription factor activity
transcription
transcription factor activity
transcription factor complex
transforming growth factor beta receptor signaling pathway
284
Klf6
1.26743
9.66145
8.39402
0.013555441
1346211
1427742_a_at
Kruppel-like factor 6 (Klf6), mRNA.
cytokine-mediated signaling pathway
cytoplasm
DNA binding
intracellular
metal ion binding
nucleic acid binding
nucleus
regulation of transcription, DNA-dependent
transcription
zinc ion binding
285
1.26526
6.12265
4.85739
0.0061382665
1359967
1442336_at
ESTs, Weakly similar to I58401 protein-tyrosine kinase (EC 2.7.1.112) JAK3 - mouse [M.musculus]
286
1.26436
6.14276
4.87840
0.0030904974
1350169
AFFX-r2-Bs-phe-5_at
287
1.26398
9.77382
8.50984
0.0097962752
1343955
1419874_x_at
Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus]
288
Adamtsl4
1.26119
9.94006
8.67887
0.00014834265
1349134
1451932_a_at
ADAMTS-like 4 (Adamtsl4), mRNA.
apoptosis
extracellular matrix
extracellular matrix organization
extracellular region
interstitial matrix
metalloendopeptidase activity
peptidase activity
289
1.25987
4.58688
3.32701
0.0077753575
1362992
1445598_at
ESTs
290
1.25817
5.43811
4.17994
0.0066423458
1357586
1439638_at
Transcribed locus
291
1.25787
6.42423
5.16636
0.017825043
1363275
1445900_at
ESTs
292
Ankrd33b
1.25125
9.40418
8.15293
0.009011346
1342147
1453287_at
ankyrin repeat domain 33B (Ankrd33b), transcript variant 1, mRNA.
DNA binding
293
1.25060
7.86850
6.61790
5.9265989e-05
1362558
1445148_at
Mus musculus 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230091K16 product:unknown EST, full insert sequence.
294
Arrdc3
1.24905
9.90369
8.65464
0.0025965571
1366423
1454617_at
arrestin domain containing 3 (Arrdc3), mRNA.
cytoplasm
295
1.24780
9.56617
8.31837
0.0098371036
1367085
1455744_at
Transcribed locus
296
1.24526
8.47468
7.22942
0.00010220189
1369131
1458469_at
ESTs
297
Fmo2
1.24508
8.75433
7.50925
0.0020491131
1372269
1453435_a_at
flavin containing monooxygenase 2 (Fmo2), mRNA.
endoplasmic reticulum
FAD binding
flavin-containing monooxygenase activity
integral to membrane
intrinsic to endoplasmic reticulum membrane
magnesium ion binding
membrane
microsome
monooxygenase activity
NADP or NADPH binding
oxidation reduction
oxidoreductase activity
oxygen and reactive oxygen species metabolic process
298
1.24378
5.46755
4.22377
0.013621896
1362441
1445028_at
Transcribed locus
299
Mbnl1
1.24375
9.33873
8.09498
0.01758482
1368639
1457924_at
muscleblind-like 1 (Drosophila) (Mbnl1), mRNA.
cytoplasm
metal ion binding
mRNA splice site selection
nucleic acid binding
nucleus
nucleus
regulation of alternative nuclear mRNA splicing, via spliceosome
RNA binding
skeletal muscle tissue development
zinc ion binding
300
1.23969
6.85554
5.61586
0.0020724092
1363491
1446118_at
ESTs
301
Klf5
1.23721
6.68508
5.44787
0.020552496
1341382
1451739_at
Kruppel-like factor 5, mRNA (cDNA clone MGC:13705 IMAGE:4208633)
angiogenesis
DNA binding
DNA binding
intracellular
metal ion binding
microvillus assembly
nucleic acid binding
nucleus
positive regulation of transcription
protein binding
regulation of transcription, DNA-dependent
transcription
transcription factor activity
transcription factor activity
zinc ion binding
302
Anxa6
1.23384
8.84961
7.61577
0.0016929202
1359922
1442288_at
Annexin A6, mRNA (cDNA clone MGC:6574 IMAGE:3482035)
calcium ion binding
calcium ion transport
calcium-dependent phospholipid binding
cytoplasm
perinuclear region of cytoplasm
regulation of muscle contraction
303
Rtn4
1.23378
8.77821
7.54443
0.00018573031
1356245
1437224_at
reticulon 4 (Rtn4), transcript variant 5, mRNA.
angiogenesis
cell projection
cell soma
endoplasmic reticulum
integral to endoplasmic reticulum membrane
integral to membrane
membrane
negative regulation of anti-apoptosis
negative regulation of axon extension
nervous system development
nuclear envelope
regulation of cell migration
304
Mafb
1.23342
9.43076
8.19733
0.0050867127
1341365
1451716_at
V-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA
brain segmentation
DNA binding
inner ear morphogenesis
nucleus
positive regulation of transcription from RNA polymerase II promoter
protein binding
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
respiratory gaseous exchange
rhombomere 5 development
rhombomere 6 development
segment specification
sequence-specific DNA binding
transcription
transcription factor activity
transcription factor complex
305
Slc2a1
1.23282
8.34026
7.10744
0.010865646
1345886
1426599_a_at
solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA.
basolateral plasma membrane
carbohydrate transport
cytoplasm
glucose transmembrane transporter activity
glucose transport
integral to membrane
intracellular
membrane
plasma membrane
protein binding
substrate-specific transmembrane transporter activity
sugar:hydrogen symporter activity
transmembrane transport
transport
transporter activity
306
1.23141
7.60777
6.37636
0.0046550118
1336117
1427363_at
Mus musculus, clone IMAGE:3584279, mRNA
307
5730416O20Rik
1.23064
7.83394
6.60330
0.0045977529
1366017
1454141_at
PREDICTED: RIKEN cDNA 5730416O20 gene (5730416O20Rik), mRNA.
308
Tuba1c
1.23045
7.07031
5.83986
6.8476556e-05
1348183
1448232_x_at
tubulin, alpha 1C (Tuba1c), mRNA.
GTP binding
GTPase activity
microtubule
microtubule-based movement
microtubule-based process
nucleotide binding
protein complex
protein polymerization
structural molecule activity
309
Cyb561
1.22843
8.83205
7.60362
0.0021148495
1328951
1417507_at
cytochrome b-561 (Cyb561), mRNA.
cytoplasmic vesicle
electron transport chain
ferric-chelate reductase activity
integral to membrane
iron ion binding
membrane
metal ion binding
transport
310
1.22841
7.17373
5.94532
0.0044366395
1351702
1430183_at
Transcribed locus
311
1.22524
7.95273
6.72749
0.0020691697
1354351
1433898_at
Transcribed locus
312
Sbno2
1.22463
8.13671
6.91209
4.8505589e-05
1357416
1439349_at
Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209)
macrophage activation during immune response
negative regulation of transcription, DNA-dependent
regulation of inflammatory response
regulation of transcription, DNA-dependent
transcription
transcription repressor activity
313
1.22429
4.46168
3.23739
0.00040290366
1368036
1457231_at
ESTs
314
Malat1
1.22406
9.59848
8.37442
6.6830051e-06
1355678
1436202_at
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA.
315
Nisch
1.22061
8.28804
7.06744
0.0031344187
1346968
1433757_a_at
Imidazoline receptor I-1-like protein
actin cytoskeleton organization
apoptosis
cell communication
cytoplasm
cytosol
endosome
integrin binding
membrane
negative regulation of cell migration
phosphoinositide binding
plasma membrane
protein binding
Rac protein signal transduction
receptor activity
316
Lgals3
1.21364
8.96469
7.75105
0.013594973
1335676
1426808_at
lectin, galactose binding, soluble 3 (Lgals3), transcript variant 2, mRNA.
cell differentiation
cytoplasm
cytoplasm
extracellular matrix organization
IgE binding
nucleus
nucleus
protein binding
proteinaceous extracellular matrix
skeletal system development
sugar binding
317
Slc38a2
1.21358
11.48133
10.26774
0.012518606
1335613
1426722_at
solute carrier family 38, member 2 (Slc38a2), mRNA.
amino acid transmembrane transporter activity
amino acid transport
integral to membrane
ion transport
membrane
plasma membrane
sodium ion binding
sodium ion transport
symporter activity
transport
318
1.21190
8.59869
7.38678
0.0053616448
1353535
1432787_at
Transcribed locus
319
Dynlt1
1.21168
12.39421
11.18253
0.024513423
1346320
1428116_a_at
Dynein light chain Tctex-type 1 (Dynlt1), mRNA
axonemal dynein complex
cytoplasmic dynein complex
cytoplasmic dynein complex
dynein complex
Golgi apparatus
microtubule
microtubule-based process
motor activity
protein binding
320
Pcyt1a
1.21066
9.38220
8.17154
0.01795718
1344488
1421957_a_at
phosphate cytidylyltransferase 1, choline, alpha isoform (Pcyt1a), mRNA.
biosynthetic process
catalytic activity
choline-phosphate cytidylyltransferase activity
cytoplasm
endoplasmic reticulum membrane
glycogen granule
membrane
nucleotidyltransferase activity
phosphatidylcholine biosynthetic process
phosphatidylcholine biosynthetic process
phospholipid biosynthetic process
response to abiotic stimulus
transferase activity
321
1.20806
8.62102
7.41295
0.00019300245
1362845
1445443_at
ESTs, Weakly similar to I58401 protein-tyrosine kinase (EC 2.7.1.112) JAK3 - mouse [M.musculus]
322
1.20539
7.42639
6.22101
0.00052185778
1364822
1447526_at
ESTs
323
Alpk2
1.20313
10.80492
9.60178
0.00034808289
1341885
1452478_at
Heart alpha-kinase
ATP binding
kinase activity
protein amino acid phosphorylation
protein serine/threonine kinase activity
transferase activity
324
100042016
1.20237
5.67200
4.46963
0.0043846322
1359020
1441231_at
PREDICTED: Mus musculus hypothetical protein LOC100042016 (LOC100042016), mRNA
325
Timp4
1.20159
9.66673
8.46515
0.030864828
1333391
1423405_at
Tissue inhibitor of metalloproteinase 4 (Timp4), mRNA
enzyme inhibitor activity
extracellular region
metalloendopeptidase inhibitor activity
proteinaceous extracellular matrix
326
1.20117
9.42709
8.22592
0.0078322303
1343415
1416983_s_at
Transcribed locus
327
Tgm2
1.20099
9.77226
8.57127
0.0011256794
1345648
1426004_a_at
transglutaminase 2, C polypeptide (Tgm2), mRNA.
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
acyltransferase activity
branching involved in salivary gland morphogenesis
calcium ion binding
cytoplasm
cytosol
G-protein coupled receptor protein signaling pathway
GTP binding
membrane
metal ion binding
peptide cross-linking
positive regulation of cell adhesion
protein-glutamine gamma-glutamyltransferase activity
proteinaceous extracellular matrix
salivary gland cavitation
transferase activity
328
1.20065
6.26205
5.06140
0.006235222
1350147
AFFX-LysX-M_at
B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 720-990 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20).
329
1.20015
6.24945
5.04930
0.0064198008
1368775
1458068_at
ESTs
330
Gm106
1.19904
5.42989
4.23085
0.010669911
1372470
1457429_s_at
Gene model 106, (NCBI), mRNA (cDNA clone MGC:182330 IMAGE:9056224)
extracellular region
immune response
polysaccharide binding
scavenger receptor activity
331
Mt3
1.19786
8.52589
7.32803
0.00051237062
1331285
1420575_at
metallothionein 3 (Mt3), mRNA.
cellular metal ion homeostasis
copper ion binding
metal ion binding
negative regulation of neurogenesis
synaptic vesicle
zinc ion binding
332
1.19738
8.26265
7.06527
2.5277584e-05
1367275
1456160_at
Transcribed locus
333
2210416J07Rik
1.19678
6.34705
5.15027
0.014765997
1353415
1432665_at
RIKEN cDNA 2210416J07 gene
334
Atp8a1
1.19635
9.28886
8.09251
0.026542653
1333550
1423597_at
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (Atp8a1), transcript variant 2, mRNA.
ATP binding
ATP biosynthetic process
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
catalytic activity
cytoplasmic vesicle
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
integral to membrane
magnesium ion binding
membrane
metabolic process
metal ion binding
nucleotide binding
phospholipid transport
phospholipid-translocating ATPase activity
335
Darc
1.19363
9.37990
8.18627
0.00031795607
1346830
1432273_a_at
Duffy blood group, chemokine receptor (Darc), mRNA.
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
inflammatory response
integral to membrane
membrane
receptor activity
signal transducer activity
signal transduction
336
Rc3h2
1.19347
8.97618
7.78271
0.043708266
1356796
1438268_at
ring finger and CCCH-type zinc finger domains 2 (Rc3h2), mRNA.
cytoplasm
DNA binding
membrane
metal ion binding
nucleic acid binding
protein binding
zinc ion binding
337
Rcan1
1.19272
10.52955
9.33683
0.0046683857
1343342
1416601_a_at
regulator of calcineurin 1 (Rcan1), transcript variant 2, mRNA.
calcium-mediated signaling
cytoplasm
nucleus
regulation of phosphoprotein phosphatase activity
skeletal muscle fiber development
338
1.18917
7.27856
6.08939
0.0051806009
1338271
1438234_at
Transcribed locus, strongly similar to XP_573529.1 PREDICTED: similar to WD-repeat protein 26 [Rattus norvegicus]
339
A330043J11Rik
1.18868
7.15803
5.96934
0.0055674282
1357929
1440018_at
RIKEN cDNA A330043J11 gene
340
Per2
1.18369
7.67919
6.49550
0.0099998021
1363268
1445892_at
Period homolog 2 (Drosophila) (Per2), mRNA
341
1.17812
8.27400
7.09588
0.014968836
1368327
1457553_at
Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630035A22 product:unknown EST, full insert sequence.
342
Kcnf1
1.17790
5.74620
4.56831
0.031722979
1366492
1454768_at
potassium voltage-gated channel, subfamily F, member 1 (Kcnf1), mRNA.
integral to membrane
ion channel activity
ion transport
membrane
potassium channel activity
potassium ion binding
potassium ion transport
protein binding
transport
voltage-gated ion channel activity
voltage-gated potassium channel activity
voltage-gated potassium channel complex
343
Flt1
1.17585
8.00269
6.82684
0.0015282704
1349517
1454037_a_at
FMS-like tyrosine kinase 1 (Flt1), mRNA.
angiogenesis
ATP binding
cell differentiation
cell migration
identical protein binding
integral to membrane
kinase activity
membrane
multicellular organismal development
nucleotide binding
patterning of blood vessels
protein amino acid phosphorylation
protein kinase activity
protein tyrosine kinase activity
receptor activity
transferase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
vascular endothelial growth factor receptor activity
vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway
344
1.17401
7.04474
5.87073
0.0040737537
1359876
1442241_at
Transcribed locus
345
A730009E18Rik
1.17159
7.13477
5.96318
0.0087096248
1370597
1460147_at
RIKEN cDNA A730009E18 gene
346
1.16936
11.55350
10.38414
3.4424281e-05
1350161
AFFX-MURINE_b1_at
M. musculus GEN=b1 DB_XREF=gb:U01310.1 NOTE=SIF corresponding to nucleotides 5-75 of gb:U01310.1 DEF=Mus musculus C57 Black6 BC1 scRNA.
347
1.16828
7.46672
6.29843
0.0069038462
1356463
1437638_at
Transcribed locus, strongly similar to NP_780438.2 serine/arginine repetitive matrix 2 [Mus musculus]
348
Zbtb20
1.16820
10.46110
9.29291
0.0074764989
1341282
1451577_at
Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586)
DNA binding
intracellular
metal ion binding
nucleic acid binding
nucleus
protein binding
regulation of transcription, DNA-dependent
transcription
zinc ion binding
349
Ppp1r1c
1.16582
5.56626
4.40044
0.0015889793
1359760
1442121_at
protein phosphatase 1, regulatory (inhibitor) subunit 1C
350
1.16485
6.48369
5.31884
0.010868772
1367921
1457110_at
Transcribed locus
351
1.16203
8.48368
7.32165
0.031056468
1356607
1437923_at
Transcribed locus
352
1.15995
7.12699
5.96704
0.0077328444
1363986
1446621_at
Transcribed locus
353
Nfkbia
1.15970
10.52199
9.36229
0.00023469249
1371369
1438157_s_at
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA.
cytoplasm
cytosol
lipopolysaccharide-mediated signaling pathway
negative regulation of myeloid cell differentiation
negative regulation of NF-kappaB transcription factor activity
negative regulation of Notch signaling pathway
NF-kappaB binding
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
nucleus
protein import into nucleus, translocation
regulation of cell proliferation
response to exogenous dsRNA
response to lipopolysaccharide
response to muramyl dipeptide
toll-like receptor 4 signaling pathway
354
Ppp1r3c
1.15954
14.02909
12.86955
0.015172351
1337327
1433691_at
protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA.
carbohydrate metabolic process
glycogen biosynthetic process
glycogen metabolic process
protein binding
protein targeting
355
1.15929
7.44205
6.28277
8.1670879e-05
1368128
1457338_at
ESTs
356
Zbtb20
1.15763
8.37127
7.21364
0.011175876
1361015
1443471_at
Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586)
DNA binding
intracellular
metal ion binding
nucleic acid binding
nucleus
protein binding
regulation of transcription, DNA-dependent
transcription
zinc ion binding
357
Nfil3
1.15729
10.55587
9.39858
0.021407176
1330123
1418932_at
nuclear factor, interleukin 3, regulated (Nfil3), mRNA.
DNA binding
nucleus
protein dimerization activity
regulation of transcription, DNA-dependent
rhythmic process
sequence-specific DNA binding
transcription
transcription factor activity
358
Tnip2
1.15686
7.97966
6.82280
0.00011401705
1330567
1419488_at
TNFAIP3 interacting protein 2 (Tnip2), mRNA.
cytoplasm
I-kappaB kinase/NF-kappaB cascade
protein binding
359
Ankrd9
1.15676
11.34043
10.18367
0.00177508
1351041
1429300_at
ankyrin repeat domain 9 (Ankrd9), mRNA.
hydrolase activity
360
Kbtbd5
1.15675
13.18454
12.02779
0.0032049
1352351
1431043_at
Kelch repeat and BTB (POZ) domain containing 5, mRNA (cDNA clone MGC:169513 IMAGE:8860908)
protein binding
361
Socs2
1.15631
8.84492
7.68861
0.0019458581
1339494
1449109_at
suppressor of cytokine signaling 2 (Socs2), mRNA.
growth hormone receptor binding
intracellular signaling cascade
lactation
lactation
mammary gland alveolus development
mammary gland alveolus development
modification-dependent protein catabolic process
negative regulation of JAK-STAT cascade
negative regulation of multicellular organism growth
negative regulation of multicellular organism growth
negative regulation of signal transduction
positive regulation of neuron differentiation
regulation of growth
regulation of multicellular organism growth
362
1.15463
8.66836
7.51373
0.00060993199
1368782
1458075_at
Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930079L03 product:unknown EST, full insert sequence.
363
Myc
1.15458
8.29910
7.14452
0.0011867783
1345189
1424942_a_at
myelocytomatosis oncogene (Myc), mRNA.
activation of caspase activity
activation of pro-apoptotic gene products
activation of pro-apoptotic gene products
axon
B cell apoptosis
detection of mechanical stimulus involved in sensory perception of sound
DNA binding
DNA fragmentation involved in apoptosis
induction of apoptosis by intracellular signals
induction of apoptosis by intracellular signals
middle ear morphogenesis
negative regulation of protein binding
negative regulation of specific transcription from RNA polymerase II promoter
negative regulation of survival gene product expression
negative regulation of survival gene product expression
nuclear body
nucleus
nucleus
pigmentation
positive regulation of B cell apoptosis
positive regulation of catalytic activity
positive regulation of cell proliferation
positive regulation of cell proliferation
positive regulation of cell proliferation
positive regulation of transcription from RNA polymerase II promoter
protein binding
protein binding
protein processing
regulation of apoptosis
regulation of gene expression
regulation of transcription
regulation of transcription, DNA-dependent
release of cytochrome c from mitochondria
response to alkaloid
response to radiation
response to radiation
skeletal system morphogenesis
spindle
transcription
transcription factor activity
transcription regulator activity
364
1.15310
7.90092
6.74782
0.0050191107
1338563
1445689_at
Transcribed locus
365
Nrip1
1.15306
10.43235
9.27929
0.017572764
1339476
1449089_at
nuclear receptor interacting protein 1 (Nrip1), mRNA.
histone deacetylase binding
histone deacetylase complex
lipid storage
negative regulation of transcription from RNA polymerase II promoter
nucleus
ovarian follicle rupture
ovulation
protein binding
receptor activity
receptor binding
regulation of transcription, DNA-dependent
retinoid X receptor binding
transcription
transcription corepressor activity
366
Heatr5a
1.15166
6.72378
5.57212
0.012329639
1358405
1440543_at
HEAT repeat containing 5A, mRNA (cDNA clone MGC:99412 IMAGE:30544145)
367
1.15138
6.76704
5.61566
0.022923912
1358586
1440728_at
Transcribed locus
368
1.15064
10.84541
9.69477
0.00039592468
1357272
1439153_at
Transcribed locus
369
Nr2c2
1.14898
8.31718
7.16821
0.00043507822
1341279
1451569_at
CD-1 orphan receptor TAK1 (TAK1)
DNA binding
ligand-dependent nuclear receptor activity
metal ion binding
nucleus
receptor activity
regulation of transcription, DNA-dependent
sequence-specific DNA binding
spermatocyte division
spermatogenesis
spermatogenesis
steroid hormone receptor activity
transcription
transcription factor activity
zinc ion binding
370
Nmb
1.14855
8.24963
7.10108
0.00060598368
1330502
1419405_at
neuromedin B (Nmb), mRNA.
extracellular region
neuropeptide signaling pathway
371
Ier3
1.14837
9.70240
8.55404
0.013183251
1343904
1419647_a_at
immediate early response 3 (Ier3), mRNA.
integral to membrane
membrane
372
Sf3b1
1.14610
8.57682
7.43072
0.011359553
1329812
1418561_at
splicing factor 3b, subunit 1 (Sf3b1), mRNA.
anterior/posterior pattern formation
binding
chromatin binding
mRNA processing
nuclear mRNA splicing, via spliceosome
nucleus
protein binding
RNA splicing
RNA splicing factor activity, transesterification mechanism
spliceosomal complex
373
1.14387
10.37380
9.22993
0.00099137721
1357496
1439537_at
ESTs
374
Chd7
1.14365
9.50864
8.36499
0.00052102611
1356511
1437745_at
chromodomain helicase DNA binding protein 7 (Chd7), mRNA.
adult heart development
adult walking behavior
ATP binding
ATP-dependent helicase activity
blood circulation
blood vessel development
camera-type eye development
chromatin
chromatin assembly or disassembly
chromatin binding
chromatin modification
DNA binding
ear morphogenesis
embryonic hindlimb morphogenesis
female genitalia development
heart morphogenesis
helicase activity
hydrolase activity
in utero embryonic development
inner ear morphogenesis
locomotory behavior
nose development
nucleic acid binding
nucleotide binding
nucleus
palate development
positive regulation of multicellular organism growth
regulation of transcription, DNA-dependent
sensory perception of sound
transcription
375
1.14289
6.46291
5.32001
0.017572419
1357282
1439165_at
Transcribed locus
376
Fmo2
1.14276
9.12436
7.98160
0.008085639
1332998
1422904_at
flavin containing monooxygenase 2 (Fmo2), mRNA.
endoplasmic reticulum
FAD binding
flavin-containing monooxygenase activity
integral to membrane
intrinsic to endoplasmic reticulum membrane
magnesium ion binding
membrane
microsome
monooxygenase activity
NADP or NADPH binding
oxidation reduction
oxidoreductase activity
oxygen and reactive oxygen species metabolic process
377
6430548M08Rik
1.14057
7.58034
6.43977
0.0034030352
1335426
1426446_at
RIKEN cDNA 6430548M08 gene (6430548M08Rik), mRNA.
378
D16H22S680E
1.13845
7.67794
6.53948
0.00040367059
1363991
1446626_at
DNA segment, Chr 16, human D22S680E, expressed (D16H22S680E), mRNA
379
Oxct1
1.13814
9.78723
8.64909
0.02992099
1347378
1436750_a_at
3-oxoacid CoA transferase 1 (Oxct1), nuclear gene encoding mitochondrial protein, mRNA.
3-oxoacid CoA-transferase activity
cellular ketone body metabolic process
CoA-transferase activity
ketone body catabolic process
metabolic process
mitochondrion
transferase activity
380
Entpd1
1.13640
7.00436
5.86796
0.00011146441
1365654
1453586_at
Ectonucleoside triphosphate diphosphohydrolase 1, mRNA (cDNA clone MGC:18369 IMAGE:3674983)
ATP binding
ATP catabolic process
basal lamina
calcium ion binding
G-protein coupled receptor protein signaling pathway
hydrolase activity
integral to membrane
magnesium ion binding
membrane
nucleoside-diphosphatase activity
nucleoside-triphosphatase activity
nucleotide binding
platelet activation
purine ribonucleoside diphosphate catabolic process
381
Pde4b
1.13573
9.65420
8.51847
0.012432653
1360303
1442700_at
Phosphodiesterase 4B, cAMP specific, mRNA (cDNA clone IMAGE:5354427)
3',5'-cyclic-AMP phosphodiesterase activity
smooth muscle contraction
382
1.13503
6.66708
5.53205
0.024055487
1356817
1438301_at
Transcribed locus
383
Gramd1b
1.13435
7.35548
6.22112
0.0013933987
1355059
1435229_at
GRAM domain containing 1B, mRNA (cDNA clone MGC:99432 IMAGE:30616509)
integral to membrane
membrane
384
Sult1a1
1.12947
10.46755
9.33809
0.0029469708
1346056
1427345_a_at
Sulfotransferase family 1A, phenol-preferring, member 1 (Sult1a1), mRNA
aryl sulfotransferase activity
cytoplasm
lipid metabolic process
nucleotide binding
steroid metabolic process
sulfotransferase activity
transferase activity
tyrosine-ester sulfotransferase activity
385
1.12943
8.37121
7.24179
0.00080094501
1367984
1457177_at
Transcribed locus
386
Ttn
1.12497
12.58297
11.45800
0.046812008
1361527
1444083_at
titin (Ttn), transcript variant N2-B, mRNA.
A band
adult heart development
ATP binding
calcium ion binding
calmodulin binding
cardiac myofibril assembly
cytoplasm
forward locomotion
heart morphogenesis
I band
in utero embryonic development
kinase activity
M band
magnesium ion binding
metal ion binding
muscle contraction
muscle myosin complex
nucleotide binding
nucleus
protein amino acid phosphorylation
protein binding
protein kinase activity
protein serine/threonine kinase activity
sarcomere
sarcomere organization
sarcomere organization
somitogenesis
striated muscle cell development
structural constituent of cytoskeleton
structural constituent of muscle
transferase activity
Z disc
387
Parp3
1.12428
9.12449
8.00021
0.0011437022
1345779
1426210_x_at
NAD+ ADP-ribosyltransferase 3 PARP-3
transferase activity
388
1.12391
7.26720
6.14329
0.0095634842
1361305
1443848_at
ESTs
389
Gpt2
1.12115
10.71996
9.59881
0.01663894
1347820
1438385_s_at
Glutamic pyruvate transaminase (alanine aminotransferase) 2, mRNA (cDNA clone MGC:37704 IMAGE:5065322)
biosynthetic process
catalytic activity
L-alanine:2-oxoglutarate aminotransferase activity
pyridoxal phosphate binding
transaminase activity
transferase activity
transferase activity, transferring nitrogenous groups
390
Egr2
1.11905
6.01443
4.89538
0.0047284267
1336323
1427683_at
early growth response 2 (Egr2), mRNA.
brain segmentation
DNA binding
facial nerve structural organization
intracellular
metal ion binding
motor axon guidance
myelination
nucleic acid binding
nucleus
nucleus
positive regulation of transcription from RNA polymerase II promoter
regulation of ossification
regulation of transcription
regulation of transcription, DNA-dependent
rhombomere 3 development
rhombomere 3 formation
rhombomere 5 formation
rhythmic behavior
rhythmic behavior
Schwann cell differentiation
transcription
transcription factor activity
transcription factor activity
transcription regulator activity
zinc ion binding
391
1.11886
6.59251
5.47365
0.015613648
1363080
1445695_at
Transcribed locus
392
1.11670
6.82481
5.70811
0.003539699
1364823
1447527_at
ESTs
393
Pkp4
1.11402
8.91918
7.80516
0.027697751
1341673
1452209_at
plakophilin 4 (Pkp4), transcript variant 2, mRNA.
binding
cell adhesion
cell junction
protein binding
394
1.11391
6.96359
5.84969
0.012339394
1350154
AFFX-ThrX-M_at
B. subtilis GEN=thrC, thrB DB_XREF=gb:X04603.1 NOTE=SIF corresponding to nucleotides 995-1562 of gb:X04603.1, not 100% identical DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectivel
395
1.11053
5.99907
4.88854
0.01874233
1357855
1439933_at
Transcribed locus
396
Cwf19l2
1.10979
6.36899
5.25920
0.00087025504
1365728
1453688_at
CWF19-like 2, cell cycle control (S. pombe), mRNA (cDNA clone MGC:159188 IMAGE:40130000)
397
Selp
1.10882
6.82168
5.71286
0.0078711707
1340074
1449906_at
selectin, platelet (Selp), mRNA.
binding
calcium-dependent protein binding
cell adhesion
external side of plasma membrane
glycoprotein binding
heterophilic cell adhesion
inflammatory response
integral to membrane
leukocyte adhesion
leukocyte tethering or rolling
membrane
membrane fraction
platelet alpha granule membrane
protein binding
sialic acid binding
sugar binding
398
1.10641
8.06433
6.95792
0.0001543038
1359356
1441594_at
Mus musculus 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130072L14 product:unclassifiable, full insert sequence.
399
1.10539
6.49034
5.38495
0.0098566834
1362172
1444749_at
Transcribed locus
400
Itga5
1.10487
7.95012
6.84525
0.0029925649
1344810
1423267_s_at
integrin alpha 5 (fibronectin receptor alpha) (Itga5), mRNA.
calcium ion binding
cell adhesion
cell-cell adhesion mediated by integrin
cell-substrate junction assembly
external side of plasma membrane
heterophilic cell adhesion
integral to membrane
integrin binding
integrin complex
integrin-mediated signaling pathway
leukocyte adhesion
membrane
memory
protein binding
receptor activity
synaptosome
401
1.10315
9.81304
8.70990
0.0038448663
1355793
1436387_at
Transcribed locus
402
Glt28d2
1.10299
8.81785
7.71486
0.0085713207
1366899
1455455_at
glycosyltransferase 28 domain containing 2 (Glt28d2), mRNA.
transferase activity
403
Sphk1
1.10249
7.23079
6.12830
0.00018509136
1348987
1451596_a_at
Sphingosine kinase 1, mRNA (cDNA clone MGC:47288 IMAGE:4221357)
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
ATP binding
blood vessel development
brain development
calmodulin binding
cytoplasm
diacylglycerol kinase activity
DNA binding
inflammatory response
kinase activity
membrane fraction
negative regulation of apoptosis
nucleotide binding
positive regulation of cell proliferation
positive regulation of fibroblast proliferation
regulation of interleukin-1 beta production
soluble fraction
sphinganine kinase activity
sphinganine kinase activity
transferase activity
404
1.09399
5.15781
4.06382
0.0044320206
1367794
1456973_at
Mus musculus adult female vagina cDNA, RIKEN full-length enriched library, clone:9930108O06 product:hypothetical protein, full insert sequence.
405
Unc84b
1.09396
7.65151
6.55756
0.0040887578
1357340
1439238_at
Unc-84 homolog B (C. elegans), mRNA (cDNA clone IMAGE:5325151)
condensed nuclear chromosome
condensed nuclear chromosome
endosome
integral to membrane
membrane
nuclear chromosome, telomeric region
nuclear chromosome, telomeric region
nuclear envelope
nuclear envelope
nuclear envelope organization
nucleus
protein binding
406
Jmjd1c
1.09297
7.68047
6.58750
0.0014459286
1357909
1439998_at
Jumonji domain containing 1C, mRNA (cDNA clone IMAGE:3676222)
chromatin modification
iron ion binding
metal ion binding
nucleus
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
regulation of transcription, DNA-dependent
transcription
zinc ion binding
407
Musk
1.09244
7.73348
6.64105
0.00016309978
1340492
1450511_at
muscle, skeletal, receptor tyrosine kinase (Musk), transcript variant 5, mRNA.
ATP binding
integral to membrane
integral to plasma membrane
kinase activity
membrane
neuromuscular junction
neuromuscular junction development
nucleotide binding
plasma membrane
protein amino acid phosphorylation
protein binding
protein kinase activity
protein serine/threonine kinase activity
protein tyrosine kinase activity
receptor activity
receptor clustering
receptor clustering
regulation of synaptic growth at neuromuscular junction
regulation of transcription, DNA-dependent
transferase activity
transmembrane receptor protein tyrosine kinase activity
408
Jmjd1c
1.09158
7.60412
6.51253
0.00085002609
1365020
1448049_at
Jumonji domain containing 1C, mRNA (cDNA clone IMAGE:3676222)
chromatin modification
iron ion binding
metal ion binding
nucleus
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
regulation of transcription, DNA-dependent
transcription
zinc ion binding
409
5830407P18Rik
1.09151
6.70066
5.60915
0.00051389157
1352062
1430646_at
RIKEN cDNA 5830407P18 gene
410
Ldlr
1.08954
6.42911
5.33957
2.5007127e-05
1370038
1459403_at
Low density lipoprotein receptor, mRNA (cDNA clone MGC:29127 IMAGE:5052599)
calcium ion binding
cholesterol homeostasis
cholesterol homeostasis
cholesterol metabolic process
cholesterol transport
coated pit
endocytosis
endosome
integral to membrane
lipid metabolic process
lipid transport
lipoprotein catabolic process
lipoprotein catabolic process
lipoprotein metabolic process
low-density lipoprotein binding
low-density lipoprotein particle
low-density lipoprotein receptor activity
low-density lipoprotein receptor activity
membrane
protein binding
receptor activity
steroid metabolic process
transport
very-low-density lipoprotein receptor activity
411
Arhgap26
1.08928
6.82643
5.73715
0.00058009394
1355354
1435694_at
Rho GTPase activating protein 26 (Arhgap26), mRNA.
cell junction
cytoplasm
cytoskeleton
GTPase activator activity
intracellular
signal transduction
412
Runx1
1.08774
6.62723
5.53949
0.027192156
1358691
1440878_at
runt related transcription factor 1 (Runx1), transcript variant 2, mRNA.
ATP binding
behavioral response to pain
central nervous system development
definitive hemopoiesis
DNA binding
embryonic hemopoiesis
in utero embryonic development
liver development
neuron development
neuron differentiation
nucleus
positive regulation of angiogenesis
protein binding
regulation of transcription, DNA-dependent
response to retinoic acid
skeletal system development
transcription
transcription factor activity
413
1.08772
5.74020
4.65249
0.0013806693
1361356
1443905_at
Transcribed locus
414
Errfi1
1.08769
9.28510
8.19741
0.0017396608
1343936
1419816_s_at
ERBB receptor feedback inhibitor 1 (Errfi1), mRNA.
cytoplasm
cytosol
protein binding
receptor activity
stress-activated protein kinase signaling pathway
415
Socs2
1.08575
6.35981
5.27405
0.0060298184
1356918
1438470_at
Suppressor of cytokine signaling 2, mRNA (cDNA clone IMAGE:1068260)
growth hormone receptor binding
intracellular signaling cascade
lactation
lactation
mammary gland alveolus development
mammary gland alveolus development
modification-dependent protein catabolic process
negative regulation of JAK-STAT cascade
negative regulation of multicellular organism growth
negative regulation of multicellular organism growth
negative regulation of signal transduction
positive regulation of neuron differentiation
regulation of growth
regulation of multicellular organism growth
416
Slc38a2
1.08276
10.51223
9.42946
0.00099945353
1351240
1429593_at
solute carrier family 38, member 2 (Slc38a2), mRNA.
amino acid transmembrane transporter activity
amino acid transport
integral to membrane
ion transport
membrane
plasma membrane
sodium ion binding
sodium ion transport
symporter activity
transport
417
1.08103
7.95454
6.87352
0.01975214
1350163
AFFX-r2-Bs-dap-5_at
418
1.08017
5.50298
4.42281
0.00019151786
1368189
1457402_at
Transcribed locus
419
Rai14
1.07846
5.53769
4.45924
0.039881441
1358830
1441030_at
Retinoic acid induced 14 (Rai14), mRNA
cytoplasm
cytoskeleton
mitochondrion
420
Map3k8
1.07815
6.95983
5.88168
0.0025817066
1330348
1419208_at
mitogen-activated protein kinase kinase kinase 8 (Map3k8), mRNA.
ATP binding
cell cycle
cytoplasm
kinase activity
magnesium ion binding
MAP kinase kinase kinase activity
metal ion binding
nucleotide binding
protein amino acid phosphorylation
protein binding
protein kinase activity
protein serine/threonine kinase activity
signal transduction
transferase activity
421
Baiap2
1.07799
8.44091
7.36292
0.0056803601
1340893
1451027_at
brain-specific angiogenesis inhibitor 1-associated protein 2 (Baiap2), transcript variant 2, mRNA.
cell projection
cytoplasm
cytoskeletal adaptor activity
filopodium assembly
membrane
protein binding
Rho protein signal transduction
SH3 domain binding
signal transduction
422
Ddx6
1.07397
9.08838
8.01441
0.025677808
1334316
1424598_at
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), transcript variant 3, mRNA.
ATP binding
ATP-dependent helicase activity
cytoplasm
helicase activity
hydrolase activity
nucleic acid binding
nucleotide binding
RNA binding
423
Qser1
1.07322
8.69486
7.62163
0.025304039
1335950
1427151_at
glutamine and serine rich 1 (Qser1), mRNA.
424
D17H6S56E-5
1.07319
7.86868
6.79549
0.0057884995
1329205
1417822_at
DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942)
viral envelope
425
Zbtb20
1.07263
9.91644
8.84381
0.00015223645
1356153
1437065_at
Zinc finger and BTB domain containing 20, mRNA (cDNA clone IMAGE:6484816)
DNA binding
intracellular
metal ion binding
nucleic acid binding
nucleus
protein binding
regulation of transcription, DNA-dependent
transcription
zinc ion binding
426
Angptl7
1.07229
9.36177
8.28948
0.017681915
1341207
1451478_at
Angiopoietin-like 7, mRNA (cDNA clone MGC:32448 IMAGE:5043159)
extracellular region
receptor binding
signal transduction
427
Dynlt1
1.07150
11.91877
10.84727
0.019278066
1349428
1453473_a_at
dynein light chain Tctex-type 1 (Dynlt1), mRNA.
axonemal dynein complex
cytoplasmic dynein complex
cytoplasmic dynein complex
dynein complex
Golgi apparatus
microtubule
microtubule-based process
motor activity
protein binding
428
Gtlf3a
1.07059
9.02396
7.95337
0.003661152
1330344
1419203_at
gene trap locus F3a (Gtlf3a), non-coding RNA.
429
1.06954
6.05349
4.98396
0.0036538216
1360981
1443430_at
Transcribed locus, strongly similar to NP_034080.1 CASP2 and RIPK1 domain containing adaptor with death domain [Mus musculus]
430
1.06928
7.54515
6.47586
0.013941737
1359354
1441592_at
Transcribed locus
431
Schip1
1.06919
8.14045
7.07126
0.0026197013
1356494
1437700_at
Schwannomin interacting protein 1 (Schip1), transcript variant 4, mRNA
cytoplasm
face morphogenesis
fibroblast migration
kidney development
nitrogen compound metabolic process
palate development
platelet-derived growth factor receptor signaling pathway
post-embryonic development
protein binding
protein homodimerization activity
skeletal system morphogenesis
smooth muscle tissue development
432
1.06733
8.52040
7.45307
0.0010463113
1355200
1435459_at
Transcribed locus
433
1.06706
5.14621
4.07915
0.0042063069
1372499
1457656_s_at
Transcribed locus
434
1.06569
6.65450
5.58881
0.015726337
1359292
1441529_at
ESTs
435
Eprs
1.06552
5.31504
4.24952
0.0037629812
1351852
1430370_at
Glutamyl-prolyl-tRNA synthetase, mRNA (cDNA clone IMAGE:3482737)
aminoacyl-tRNA ligase activity
ATP binding
catalytic activity
cytoplasm
glutamate-tRNA ligase activity
glutamyl-tRNA aminoacylation
ligase activity
nucleotide binding
proline-tRNA ligase activity
prolyl-tRNA aminoacylation
RNA binding
translation
tRNA aminoacylation for protein translation
436
Car4
1.06370
8.64505
7.58135
0.00039123421
1343611
1418094_s_at
carbonic anhydrase 4 (Car4), mRNA.
anchored to membrane
carbonate dehydratase activity
lyase activity
membrane
metal ion binding
one-carbon metabolic process
plasma membrane
zinc ion binding
437
Timp1
1.06266
7.41663
6.35397
0.008884976
1342840
1460227_at
tissue inhibitor of metalloproteinase 1 (Timp1), transcript variant 2, mRNA.
basement membrane
enzyme inhibitor activity
erythrocyte maturation
extracellular region
metalloendopeptidase inhibitor activity
proteinaceous extracellular matrix
438
1.06127
5.90298
4.84171
0.0001829166
1350151
AFFX-PheX-M_at
B. subtilis GEN=pheA DB_XREF=gb:M24537.1 NOTE=SIF corresponding to nucleotides 2437-2828 of gb:M24537.1 DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofuncti
439
Spnb2
1.06124
9.16336
8.10212
0.025894344
1330384
1419255_at
spectrin beta 2 (Spnb2), transcript variant 2, mRNA.
actin binding
actin filament capping
calmodulin binding
common-partner SMAD protein phosphorylation
cortical cytoskeleton
cytoplasm
cytoskeleton
membrane
nucleus
plasma membrane
protein binding
SMAD protein nuclear translocation
spectrin
structural constituent of cytoskeleton
440
Slc19a2
1.05927
6.74951
5.69024
0.012513214
1371605
1441315_s_at
solute carrier family 19 (thiamine transporter), member 2 (Slc19a2), mRNA.
plasma membrane
thiamin transmembrane transporter activity
thiamin transport
441
Cab39
1.05857
10.38726
9.32868
0.018028408
1329711
1418432_at
calcium binding protein 39 (Cab39), mRNA.
calcium ion binding
cytoplasm
442
Ppp1r12b
1.05831
6.16103
5.10272
0.0060782452
1363227
1445850_at
Protein phosphatase 1, regulatory (inhibitor) subunit 12B, mRNA (cDNA clone MGC:175633 IMAGE:40131049)
cytoplasm
443
Rnf19a
1.05770
9.55492
8.49723
0.0056890275
1328952
1417508_at
ring finger protein 19A (Rnf19a), mRNA.
integral to membrane
ligase activity
membrane
metal ion binding
modification-dependent protein catabolic process
protein binding
zinc ion binding
444
Slc25a30
1.05593
7.68155
6.62562
0.011682809
1348550
1450018_s_at
Solute carrier family 25, member 30, mRNA (cDNA clone MGC:31367 IMAGE:4238839)
binding
integral to membrane
membrane
mitochondrial inner membrane
mitochondrion
transport
transporter activity
445
Malat1
1.05542
8.49236
7.43694
0.014303124
1341817
1452378_at
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA.
446
1.05452
11.48638
10.43186
0.0032672519
1338298
1438443_at
Transcribed locus
447
1.05361
5.97549
4.92188
0.023539672
1360531
1442956_at
Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930009B01 product:unknown EST, full insert sequence.
448
4933409K07Rik
1.05284
7.22352
6.17068
0.022269522
1372187
1447937_a_at
RIKEN cDNA 4933409K07 gene (4933409K07Rik), mRNA.
449
1.05226
7.63593
6.58367
5.9055846e-05
1371742
1442760_x_at
ESTs
450
1.05201
6.40309
5.35109
0.0023398031
1368865
1458159_at
ESTs
451
Klf6
1.05022
9.93195
8.88173
0.010269835
1337260
1433508_at
Kruppel-like factor 6 (Klf6), mRNA.
cytokine-mediated signaling pathway
cytoplasm
DNA binding
intracellular
metal ion binding
nucleic acid binding
nucleus
regulation of transcription, DNA-dependent
transcription
zinc ion binding
452
Gse1
1.04902
7.68246
6.63344
0.0095894959
1351285
1429653_at
genetic suppressor element 1 (Gse1), transcript variant 3, mRNA.
453
Fosb
1.04876
5.80195
4.75319
0.014398681
1332410
1422134_at
FBJ osteosarcoma oncogene B (Fosb), mRNA.
DNA binding
nucleus
protein dimerization activity
regulation of transcription, DNA-dependent
sequence-specific DNA binding
transcription factor activity
454
Thbs1
1.04864
7.86451
6.81588
0.020052214
1332171
1421811_at
Thrombospondin 1 (Thbs1), mRNA
calcium ion binding
cell adhesion
extracellular matrix binding
extracellular region
extracellular space
heparin binding
inflammatory response
negative regulation of angiogenesis
positive regulation of cell-substrate adhesion
protein binding
structural molecule activity
455
Ank3
1.04795
10.14639
9.09843
0.00046621924
1348997
1451628_a_at
ankyrin 3, epithelial (Ank3), transcript variant 9, mRNA.
axon
axon guidance
membrane fraction
protein binding
protein binding
synapse
synapse organization
456
Bmp6
1.04672
8.42771
7.38099
0.00023550252
1340684
1450759_at
Bone morphogenetic protein 6 (Bmp6), mRNA
BMP signaling pathway
cartilage development
cell differentiation
cytokine activity
extracellular region
extracellular space
growth
growth factor activity
inflammatory response
multicellular organismal development
ossification
osteoblast differentiation
protein binding
457
Pde4dip
1.04647
9.68914
8.64267
0.017664352
1342988
1460426_at
Phosphodiesterase 4D interacting protein (myomegalin), mRNA (cDNA clone IMAGE:4954590)
cytoplasm
Golgi apparatus
nucleus
protein binding
458
Csnk2a1
1.04549
8.78480
7.73931
0.022067362
1330208
1419034_at
casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA.
ATP binding
beta-catenin binding
kinase activity
nucleotide binding
protein amino acid autophosphorylation
protein amino acid phosphorylation
protein binding
protein kinase activity
protein kinase CK2 complex
protein phosphatase regulator activity
protein serine/threonine kinase activity
transferase activity
Wnt receptor signaling pathway
459
Bat2d
1.04456
9.62585
8.58130
0.01534984
1351133
1429433_at
BAT2 domain containing 1 (Bat2d), mRNA.
460
Ampd3
1.04320
9.26140
8.21820
4.984057e-06
1332733
1422573_at
adenosine monophosphate deaminase 3 (Ampd3), mRNA.
AMP deaminase activity
deaminase activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
nucleotide metabolic process
purine base metabolic process
purine ribonucleoside monophosphate biosynthetic process
461
Galntl2
1.04275
8.75333
7.71058
2.8193052e-05
1350997
1429236_at
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2, mRNA (cDNA clone MGC:161357 IMAGE:40143107)
calcium ion binding
Golgi apparatus
integral to membrane
manganese ion binding
membrane
polypeptide N-acetylgalactosaminyltransferase activity
sugar binding
transferase activity
transferase activity, transferring glycosyl groups
462
1.04138
7.74311
6.70173
0.0016593199
1359019
1441230_at
ESTs
463
Gcc1
1.03415
7.77170
6.73756
0.00011858369
1336880
1429033_at
golgi coiled coil 1 (Gcc1), mRNA.
cytoplasm
Golgi apparatus
membrane
464
1.03317
7.19308
6.15991
0.0091789238
1361083
1443544_at
ESTs
465
Spnb2
1.02994
7.51109
6.48115
0.005721998
1359271
1441507_at
Mus musculus, clone IMAGE:4951562, mRNA
actin binding
actin filament capping
calmodulin binding
common-partner SMAD protein phosphorylation
cortical cytoskeleton
cytoplasm
cytoskeleton
membrane
nucleus
plasma membrane
protein binding
SMAD protein nuclear translocation
spectrin
structural constituent of cytoskeleton
466
Fubp1
1.02955
7.96521
6.93567
0.0084014882
1338164
1437543_at
Far upstream element (FUSE) binding protein 1 (Fubp1), mRNA
DNA binding
nucleus
regulation of transcription, DNA-dependent
RNA binding
transcription
467
Sf3b1
1.02858
8.35082
7.32224
0.040931472
1371567
1440818_s_at
splicing factor 3b, subunit 1 (Sf3b1), mRNA.
anterior/posterior pattern formation
binding
chromatin binding
mRNA processing
nuclear mRNA splicing, via spliceosome
nucleus
protein binding
RNA splicing
RNA splicing factor activity, transesterification mechanism
spliceosomal complex
468
1.02613
8.67527
7.64914
0.021885494
1358736
1440926_at
Transcribed locus
469
Cnksr1
1.02502
10.78363
9.75861
0.004036819
1366859
1455399_at
connector enhancer of kinase suppressor of Ras 1 (Cnksr1), mRNA.
cell cortex
kinase activity
protein binding, bridging
Ras protein signal transduction
Rho protein signal transduction
470
1.02292
6.58967
5.56675
0.0072249143
1361781
1444349_at
ESTs, Highly similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus]
471
Scn3b
1.02171
5.96234
4.94063
0.013681779
1337862
1435767_at
sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA.
integral to membrane
ion channel activity
ion transport
membrane
sodium channel activity
sodium ion binding
sodium ion transport
transport
voltage-gated ion channel activity
472
Myh9
1.02146
9.96706
8.94560
0.0021536322
1328922
1417472_at
myosin, heavy polypeptide 9, non-muscle (Myh9), transcript variant 1, mRNA.
actin binding
actin filament binding
actin filament-based movement
actin-dependent ATPase activity
ADP binding
ATP binding
calmodulin binding
cell adhesion
cell cortex
cell morphogenesis involved in differentiation
cell motion
cell-cell adherens junction
cell-cell adhesion
cortical cytoskeleton
cytoplasm
establishment of meiotic spindle localization
establishment of T cell polarity
immunological synapse
immunological synapse
in utero embryonic development
meiotic metaphase I
meiotic spindle organization
microfilament motor activity
motor activity
myoblast fusion
myosin complex
neuromuscular junction
nucleotide binding
plasma membrane
plasma membrane
protein binding
regulation of cell shape
spindle
stress fiber
stress fiber
uropod
uropod
uropod organization
473
Bace1
1.02116
9.13007
8.10891
0.015274878
1349753
1455826_a_at
beta-site APP cleaving enzyme 1 (Bace1), transcript variant 2, mRNA.
aspartic-type endopeptidase activity
axon
cytoplasmic vesicle
endopeptidase activity
hydrolase activity
integral to membrane
membrane
membrane fraction
peptidase activity
proteolysis
474
Rapgef3
1.02071
5.85319
4.83249
0.002609536
1356987
1438590_at
Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), mRNA
cAMP binding
cAMP-dependent protein kinase complex
cAMP-dependent protein kinase regulator activity
cytoplasm
guanyl-nucleotide exchange factor activity
intracellular
intracellular signaling cascade
membrane
nucleotide binding
regulation of protein amino acid phosphorylation
regulation of small GTPase mediated signal transduction
small GTPase mediated signal transduction
475
1.01889
5.70721
4.68832
0.025797799
1363480
1446107_at
ESTs
476
Pdlim3
1.01886
10.38289
9.36402
0.014247984
1360866
1443299_at
PDZ and LIM domain 3 (Pdlim3), mRNA
actin cytoskeleton
actin filament organization
cytoplasm
cytoskeletal protein binding
heart development
metal ion binding
protein binding
skeletal muscle tissue development
structural constituent of muscle
structural constituent of muscle
Z disc
zinc ion binding
477
1.01886
7.67050
6.65164
0.022785558
1362679
1445273_at
ESTs, Moderately similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus]
478
1.01877
7.28687
6.26810
0.0086147713
1358665
1440847_at
Transcribed locus
479
1.01816
5.63214
4.61398
0.0064026567
1361603
1444164_at
Transcribed locus
480
Trim63
1.01734
13.31282
12.29549
0.019275634
1357030
1438704_at
tripartite motif-containing 63 (Trim63), mRNA.
contractile fiber
cytoplasm
intracellular
ligase activity
metal ion binding
modification-dependent protein catabolic process
muscle contraction
nucleus
proteasomal ubiquitin-dependent protein catabolic process
protein binding
protein binding
ubiquitin-protein ligase activity
zinc ion binding
481
Zmiz1
1.01669
7.86102
6.84432
0.031623355
1359571
1441823_at
Zinc finger, MIZ-type containing 1, mRNA (cDNA clone MGC:86031 IMAGE:6856060)
artery morphogenesis
cell aging
cytoplasm
developmental growth
heart morphogenesis
in utero embryonic development
metal ion binding
nucleus
positive regulation of fibroblast proliferation
positive regulation of transcription from RNA polymerase II promoter
protein binding
regulation of transcription, DNA-dependent
transcription
vasculogenesis
vitellogenesis
zinc ion binding
482
Slc7a8
1.01665
7.96062
6.94397
0.00080804409
1329298
1417929_at
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), mRNA.
amine transmembrane transporter activity
amino acid transmembrane transporter activity
amino acid transport
cytoplasm
integral to membrane
L-amino acid transmembrane transporter activity
L-amino acid transport
membrane
plasma membrane
transport
483
Nfkbia
1.01613
10.37119
9.35506
0.024468501
1348480
1449731_s_at
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA.
cytoplasm
cytosol
lipopolysaccharide-mediated signaling pathway
negative regulation of myeloid cell differentiation
negative regulation of NF-kappaB transcription factor activity
negative regulation of Notch signaling pathway
NF-kappaB binding
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
nucleus
protein import into nucleus, translocation
regulation of cell proliferation
response to exogenous dsRNA
response to lipopolysaccharide
response to muramyl dipeptide
toll-like receptor 4 signaling pathway
484
1.01530
7.45572
6.44042
0.0049947982
1367377
1456347_at
Transcribed locus
485
Doc2b
1.01487
6.44366
5.42879
0.00063447931
1331346
1420667_at
double C2, beta (Doc2b), mRNA.
calcium ion binding
calcium-dependent phospholipid binding
membrane
synaptic vesicle
transport
transporter activity
486
Slc2a1
1.01447
8.42996
7.41550
0.0073006463
1335530
1426600_at
solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA.
basolateral plasma membrane
carbohydrate transport
cytoplasm
glucose transmembrane transporter activity
glucose transport
integral to membrane
intracellular
membrane
plasma membrane
protein binding
substrate-specific transmembrane transporter activity
sugar:hydrogen symporter activity
transmembrane transport
transport
transporter activity
487
1.01180
6.76276
5.75096
0.0015322101
1369844
1459205_at
ESTs
488
Car9
1.01008
7.49682
6.48674
0.0010238222
1335839
1427013_at
carbonic anhydrase 9 (Car9), mRNA.
carbonate dehydratase activity
cell projection
integral to membrane
lyase activity
membrane
metal ion binding
morphogenesis of an epithelium
one-carbon metabolic process
plasma membrane
secretion
zinc ion binding
489
Rasal2
1.00889
8.42333
7.41445
0.0092771147
1338064
1436910_at
RAS protein activator like 2 (Rasal2), mRNA.
490
1.00808
7.57049
6.56241
4.8650289e-06
1362994
1445600_at
ESTs
491
Cebpb
1.00764
12.30996
11.30232
0.013467617
1330097
1418901_at
CCAAT/enhancer binding protein (C/EBP), beta (Cebpb), mRNA.
anti-apoptosis
cytoplasm
DNA binding
embryonic placenta development
fat cell differentiation
induction of apoptosis
mammary gland epithelial cell differentiation
mammary gland epithelial cell proliferation
neuron differentiation
nucleus
positive regulation of transcription
positive regulation of transcription from RNA polymerase II promoter
protein binding
protein dimerization activity
protein heterodimerization activity
protein homodimerization activity
regulation of interleukin-6 biosynthetic process
regulation of transcription, DNA-dependent
RNA polymerase II transcription factor activity, enhancer binding
sequence-specific DNA binding
transcription
transcription activator activity
transcription factor activity
492
Bmp4
1.00742
9.21748
8.21006
0.0012826571
1333004
1422912_at
bone morphogenetic protein 4 (Bmp4), mRNA.
anatomical structure formation involved in morphogenesis
angiogenesis
BMP signaling pathway
BMP signaling pathway
branching involved in lung morphogenesis
branching involved in prostate gland morphogenesis
branching involved in ureteric bud morphogenesis
bronchus development
bud dilation involved in lung branching
camera-type eye development
cartilage development
cell differentiation
cell fate commitment
cytokine activity
dorsal/ventral neural tube patterning
embryonic morphogenesis
epithelial cell proliferation involved in lung morphogenesis
erythrocyte differentiation
extracellular region
extracellular space
forebrain development
germ cell development
growth
growth factor activity
heart development
heparin binding
induction of an organ
lens induction in camera-type eye
lung alveolus development
lung development
lung morphogenesis
mammary gland formation
mesodermal cell fate determination
metanephros development
metanephros development
multicellular organismal development
negative regulation of cell proliferation
negative regulation of chondrocyte differentiation
negative regulation of epithelial cell proliferation
negative regulation of gene expression
negative regulation of myoblast differentiation
negative regulation of prostatic bud formation
negative regulation of prostatic bud formation
negative regulation of striated muscle development
neuron fate commitment
neuron fate commitment
odontogenesis of dentine-containing tooth
odontogenesis of dentine-containing tooth
ossification
osteoblast differentiation
pituitary gland development
positive regulation of bone mineralization
positive regulation of cell death
positive regulation of cell differentiation
positive regulation of gene expression
positive regulation of ossification
positive regulation of osteoblast differentiation
positive regulation of protein amino acid phosphorylation
positive regulation of transcription from RNA polymerase II promoter
post-embryonic development
prostate gland morphogenesis
protein binding
proteinaceous extracellular matrix
regulation of branching involved in prostate gland morphogenesis
regulation of cell differentiation
regulation of gene expression
regulation of gene expression
regulation of morphogenesis of a branching structure
regulation of smooth muscle cell proliferation
skeletal system development
skeletal system development
smooth muscle cell differentiation
specification of organ position
telencephalon regionalization
tissue development
trachea development
ureteric bud development
ureteric bud development
ureteric bud development
493
Tsc22d3
1.00638
12.77152
11.76514
0.0022354063
1345308
1425281_a_at
TSC22 domain family, member 3 (Tsc22d3), transcript variant 2, mRNA.
anti-apoptosis
regulation of transcription, DNA-dependent
response to osmotic stress
transcription factor activity
494
Fhl1
1.00567
9.43644
8.43077
0.002329049
1369653
1459003_at
Four and a half LIM domains 1, mRNA (cDNA clone MGC:32284 IMAGE:5012394)
cell differentiation
cytoplasm
metal ion binding
multicellular organismal development
nucleus
zinc ion binding
495
1.00385
6.52358
5.51973
0.0036576778
1359942
1442309_at
Transcribed locus
496
1.00364
9.49507
8.49143
5.3792936e-05
1357452
1439488_at
Transcribed locus
497
5033430J17Rik
1.00307
6.70694
5.70387
0.038833124
1353929
1433207_at
RIKEN cDNA 5033430J17 gene
498
1.00300
6.83631
5.83331
0.0081414923
1337634
1434752_at
Transcribed locus
499
1190002H23Rik
1.00211
8.23021
7.22811
0.013397081
1347844
1438511_a_at
Response gene to complement 32
cell cycle
cytoplasm
nucleus
protein binding
protein kinase activator activity
500
1.00138
5.51356
4.51218
0.00032741341
1363468
1446095_at
Transcribed locus