Row
Row
Gene
A-B Mean Difference
A Mean (WT+GH)
B Mean (WT-GH)
A-B p-Value
Well ID
Feature ID
Description
Gene Ontology Terms
1
Tmem120a
-1.00061
7.92511
8.92572
0.00040703644
1354940
1435031_at
transmembrane protein 120A (Tmem120a), mRNA.
integral to membrane
membrane
2
Rian
-1.00851
5.93129
6.93981
0.012721137
1346139
1427580_a_at
MRNA, MBII-343 snoRNA
nucleus
3
Ffar2
-1.01329
6.61313
7.62642
0.0032909694
1334756
1425216_at
free fatty acid receptor 2 (Ffar2), mRNA.
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
integral to membrane
lipid binding
membrane
plasma membrane
receptor activity
signal transducer activity
signal transduction
4
Gpr81
-1.01500
6.49516
7.51017
0.017782834
1356879
1438411_at
G protein-coupled receptor 81 (Gpr81), mRNA.
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
integral to membrane
membrane
plasma membrane
receptor activity
signal transducer activity
signal transduction
5
Lasp1
-1.01872
6.99963
8.01835
0.011764243
1347882
1438634_x_at
LIM and SH3 protein 1 (Lasp1), mRNA.
actin binding
actin filament binding
cytoplasm
cytoskeleton
focal adhesion
ion transport
metal ion binding
protein binding
transport
zinc ion binding
6
Nr1d1
-1.01917
9.47058
10.48975
1.1290479e-05
1335439
1426464_at
nuclear receptor subfamily 1, group D, member 1 (Nr1d1), mRNA.
circadian rhythm
DNA binding
ligand-dependent nuclear receptor activity
metal ion binding
nucleus
receptor activity
regulation of transcription, DNA-dependent
sequence-specific DNA binding
steroid hormone receptor activity
transcription
transcription factor activity
zinc ion binding
7
H2-K1
-1.02296
8.51498
9.53794
0.0026324184
1349018
1451683_x_at
MRNA similar to histocompatibility 2, D region locus 1 (cDNA clone MGC:25703 IMAGE:3675316)
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class I
antigen processing and presentation of peptide antigen via MHC class I
defense response to bacterium
external side of plasma membrane
immune response
integral to membrane
membrane
MHC class I protein complex
peptide antigen binding
positive regulation of T cell mediated cytotoxicity
8
Galm
-1.02568
5.55001
6.57569
0.0043629784
1349327
1452583_s_at
galactose mutarotase (Galm), mRNA.
aldose 1-epimerase activity
carbohydrate binding
carbohydrate metabolic process
catalytic activity
cytoplasm
hexose metabolic process
isomerase activity
protein homodimerization activity
9
Gfra2
-1.02596
4.96243
5.98839
0.0032457903
1371142
1433716_x_at
Glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2), mRNA
anchored to membrane
membrane
nervous system development
plasma membrane
receptor activity
transmembrane receptor protein tyrosine kinase signaling pathway
10
Cd74
-1.02729
9.63034
10.65762
0.0083341282
1345403
1425519_a_at
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), transcript variant 2, mRNA.
antigen processing and presentation
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
chaperone mediated protein folding requiring cofactor
chaperone mediated protein folding requiring cofactor
defense response
endoplasmic reticulum
external side of plasma membrane
Golgi apparatus
immune response
immunoglobulin mediated immune response
integral to membrane
integral to plasma membrane
intracellular protein transport
intracellular protein transport
late endosome
lysosome
membrane
MHC class II protein binding
multivesicular body
negative regulation of T cell differentiation
negative thymic T cell selection
plasma membrane
plasma membrane
positive regulation of T cell differentiation
positive thymic T cell selection
protein binding
protein complex assembly
11
1110020P15Rik
-1.02944
10.08173
11.11118
0.00011356004
1347039
1434341_x_at
RIKEN cDNA 1110020P15 gene, mRNA (cDNA clone MGC:37480 IMAGE:4984172)
electron transport chain
membrane
mitochondrial electron transport, ubiquinol to cytochrome c
mitochondrial envelope
mitochondrial inner membrane
mitochondrion
respiratory chain
transport
ubiquinol-cytochrome-c reductase activity
12
Atn1
-1.03129
6.94838
7.97967
0.039907141
1344266
1421149_a_at
atrophin 1 (Atn1), mRNA.
cytoplasm
negative regulation of transcription from RNA polymerase II promoter
nucleus
nucleus
protein binding
toxin metabolic process
toxin receptor binding
transcription corepressor activity
13
Chst1
-1.03223
7.47437
8.50659
0.00048840277
1339524
1449147_at
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (Chst1), mRNA.
carbohydrate metabolic process
Golgi apparatus
Golgi membrane
inflammatory response
integral to membrane
keratan sulfotransferase activity
membrane
sulfotransferase activity
transferase activity
14
AI317395
-1.03381
5.44294
6.47675
0.00083713221
1334972
1425596_at
Expressed sequence AI317395 (AI317395), mRNA
carbohydrate transport
integral to membrane
ion transport
membrane
plasma membrane
sodium ion binding
sodium ion transport
sugar:hydrogen symporter activity
symporter activity
transport
15
Oaf
-1.03566
8.15390
9.18956
0.00029017291
1333913
1424086_at
OAF homolog (Drosophila) (Oaf), mRNA.
16
-1.03638
5.71272
6.74910
0.0025297024
1358871
1441071_at
Transcribed locus, strongly similar to XP_532200.2 PREDICTED: similar to potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 1 [Canis familiaris]
17
Wdyhv1
-1.03912
6.37728
7.41640
0.019220843
1371114
1432489_a_at
WDYHV motif containing 1 (Wdyhv1), mRNA.
cytosol
nucleus
protein catabolic process
protein modification process
protein N-terminal glutamine amidohydrolase activity
18
Hspa4
-1.03915
7.39914
8.43829
0.010798742
1327861
1416147_at
heat shock protein 4 (Hspa4), mRNA.
ATP binding
cytoplasm
nucleotide binding
response to stress
19
Ccdc69
-1.03945
7.16094
8.20039
0.0029006027
1370785
1419985_s_at
coiled-coil domain containing 69 (Ccdc69), mRNA.
20
H2-K1
-1.04055
8.51438
9.55494
0.016792167
1345191
1424948_x_at
Histocompatibility 2, K1, K region, mRNA (cDNA clone MGC:7052 IMAGE:3156482)
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class I
antigen processing and presentation of peptide antigen via MHC class I
defense response to bacterium
external side of plasma membrane
immune response
integral to membrane
membrane
MHC class I protein complex
peptide antigen binding
positive regulation of T cell mediated cytotoxicity
21
Dpp4
-1.04119
3.70159
4.74279
0.049283963
1372680
1459973_x_at
Dipeptidylpeptidase 4, mRNA (cDNA clone MGC:14076 IMAGE:3982742)
aminopeptidase activity
extracellular region
hydrolase activity
integral to membrane
intercellular canaliculus
membrane
peptidase activity
plasma membrane
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
22
2900062L11Rik
-1.04874
7.43470
8.48343
0.00040067965
1336703
1428333_at
RIKEN cDNA 2900062L11 gene (2900062L11Rik), non-coding RNA.
23
Thrsp
-1.04987
10.27408
11.32395
0.0075397023
1344742
1422973_a_at
thyroid hormone responsive SPOT14 homolog (Rattus) (Thrsp), mRNA.
nucleus
24
Ptp4a1
-1.05128
7.62973
8.68101
0.0029653493
1330199
1419024_at
Protein tyrosine phosphatase 4a1 (Ptp4a1), mRNA
cell cycle
cytoplasm
dephosphorylation
endoplasmic reticulum
endosome
hydrolase activity
membrane
multicellular organismal development
phosphatase activity
phosphoprotein phosphatase activity
plasma membrane
positive regulation of cell migration
prenylated protein tyrosine phosphatase activity
protein amino acid dephosphorylation
protein tyrosine phosphatase activity
25
LOC634842
-1.05588
4.98255
6.03843
0.021579116
1366597
1454965_at
PREDICTED: similar to D430039N05Rik protein, transcript variant 2 (LOC634842), mRNA.
26
Orm1
-1.05971
7.32764
8.38734
0.040411285
1340915
1451054_at
orosomucoid 1 (Orm1), mRNA.
acute-phase response
binding
extracellular region
extracellular space
regulation of immune system process
transport
transporter activity
27
Arhgap18
-1.06452
5.29133
6.35586
0.0094807321
1335789
1426952_at
Rho GTPase activating protein 18 (Arhgap18), mRNA.
GTPase activator activity
intracellular
signal transduction
28
Vapb
-1.06646
8.71513
9.78159
0.019607669
1333185
1423152_at
vesicle-associated membrane protein, associated protein B and C (Vapb), mRNA.
integral to membrane
membrane
membrane fraction
plasma membrane
structural molecule activity
29
Cd248
-1.06728
8.44124
9.50853
0.011237348
1328897
1417439_at
CD248 antigen, endosialin (Cd248), mRNA.
binding
calcium ion binding
cytoplasm
integral to membrane
membrane
plasma membrane
sugar binding
30
Lasp1
-1.06908
7.79925
8.86832
0.0017413234
1342795
1460173_at
LIM and SH3 protein 1 (Lasp1), mRNA.
actin binding
actin filament binding
cytoplasm
cytoskeleton
focal adhesion
ion transport
metal ion binding
protein binding
transport
zinc ion binding
31
1700037H04Rik
-1.07072
7.15197
8.22269
0.011764295
1330770
1419742_at
RIKEN cDNA 1700037H04 gene (1700037H04Rik), mRNA.
32
Fzd7
-1.07118
7.49131
8.56249
0.0034468784
1340171
1450044_at
frizzled homolog 7 (Drosophila) (Fzd7), mRNA.
cell surface receptor linked signal transduction
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
integral to membrane
membrane
multicellular organismal development
non-G-protein coupled 7TM receptor activity
receptor activity
signal transducer activity
signal transduction
transmembrane receptor activity
Wnt receptor signaling pathway
33
Dusp10
-1.07392
6.82520
7.89912
0.011016504
1328664
1417163_at
dual specificity phosphatase 10 (Dusp10), mRNA.
cytoplasm
dephosphorylation
hydrolase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
nucleus
phosphatase activity
phosphoprotein phosphatase activity
protein amino acid dephosphorylation
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
34
Sox7
-1.07531
6.92727
8.00258
0.014218672
1328185
1416564_at
SRY-box containing gene 7 (Sox7), mRNA
DNA binding
nucleus
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
transcription
transcription factor activity
35
Sox18
-1.07632
8.65397
9.73029
0.017757859
1339514
1449135_at
SRY-box containing gene 18 (Sox18), mRNA.
angiogenesis
DNA binding
nucleus
regulation of transcription, DNA-dependent
transcription
transcription factor activity
vasculogenesis
36
Apoc1
-1.07823
9.05175
10.12998
0.02881953
1329001
1417561_at
apolipoprotein C-I (Apoc1), transcript variant 2, mRNA.
cholesterol metabolic process
extracellular region
lipid transport
lipoprotein metabolic process
transport
triglyceride metabolic process
very-low-density lipoprotein particle
37
Gm7120
-1.08322
8.61815
9.70138
0.0098337064
1335537
1426607_at
predicted gene 7120 (Gm7120), mRNA.
integral to membrane
membrane
38
Acvr1c
-1.09124
4.24643
5.33767
0.01540413
1356824
1438309_at
Activin A receptor, type IC, mRNA (cDNA clone IMAGE:1196242)
activin binding
apoptosis
ATP binding
cell surface
determination of left/right symmetry
in utero embryonic development
integral to membrane
kinase activity
lipid storage
magnesium ion binding
manganese ion binding
membrane
metal ion binding
negative regulation of insulin secretion
nucleotide binding
positive regulation of apoptosis
protein amino acid phosphorylation
protein kinase activity
protein serine/threonine kinase activity
receptor activity
response to dietary excess
response to glucose stimulus
response to insulin stimulus
transferase activity
transforming growth factor beta receptor activity
transmembrane receptor protein serine/threonine kinase activity
trophectodermal cell proliferation
39
Nat8l
-1.09216
6.11911
7.21126
0.048054528
1356002
1436702_at
N-acetyltransferase 8-like (Nat8l), mRNA.
acyltransferase activity
integral to membrane
membrane
metabolic process
N-acetyltransferase activity
transferase activity
40
Pgd
-1.09389
8.70124
9.79513
0.0092673261
1344891
1423706_a_at
phosphogluconate dehydrogenase (Pgd), mRNA.
binding
catalytic activity
coenzyme binding
metabolic process
NADP or NADPH binding
oxidation reduction
oxidoreductase activity
pentose biosynthetic process
pentose-phosphate shunt
phosphogluconate 2-dehydrogenase activity
phosphogluconate dehydrogenase (decarboxylating) activity
41
Efhd1
-1.10131
7.52676
8.62807
0.002014924
1338998
1448507_at
EF hand domain containing 1 (Efhd1), mRNA.
calcium ion binding
mitochondrial inner membrane
neuron projection development
42
Insig1
-1.10152
7.42066
8.52218
0.00010721953
1366445
1454671_at
Insulin induced gene 1 (Insig1), mRNA
cholesterol biosynthetic process
cholesterol metabolic process
cranial suture morphogenesis
endoplasmic reticulum
inner ear morphogenesis
integral to membrane
lipid metabolic process
membrane
middle ear morphogenesis
negative regulation of fat cell differentiation
negative regulation of fatty acid biosynthetic process
negative regulation of steroid biosynthetic process
palate development
protein binding
response to sterol depletion
steroid metabolic process
sterol biosynthetic process
triglyceride metabolic process
43
Mmd
-1.10155
9.65753
10.75908
0.00045441942
1333464
1423489_at
monocyte to macrophage differentiation-associated (Mmd), mRNA.
cytolysis
endosome
integral to membrane
lysosome
membrane
receptor activity
44
Acsm3
-1.10226
6.45910
7.56137
0.010393606
1345423
1425559_a_at
acyl-CoA synthetase medium-chain family member 3 (Acsm3), transcript variant 3, mRNA.
ATP binding
butyrate-CoA ligase activity
catalytic activity
fatty acid biosynthetic process
fatty acid metabolic process
fatty-acid ligase activity
ligase activity
lipid metabolic process
magnesium ion binding
metabolic process
metal ion binding
mitochondrial matrix
mitochondrion
nucleotide binding
45
Lrrc17
-1.10287
6.27650
7.37937
0.0001655887
1351306
1429679_at
leucine rich repeat containing 17 (Lrrc17), mRNA.
protein binding
46
Tmem45b
-1.10344
9.11362
10.21705
0.0025442389
1334125
1424357_at
transmembrane protein 45b (Tmem45b), mRNA.
integral to membrane
membrane
47
Cotl1
-1.10352
4.76023
5.86375
5.2734902e-07
1371345
1437811_x_at
Coactosin-like 1 (Dictyostelium) (Cotl1), mRNA
actin binding
cytoplasm
cytoskeleton
intracellular
protein binding
48
Prkar2b
-1.10453
7.52964
8.63417
0.0046496634
1357007
1438664_at
protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), mRNA.
cAMP binding
cAMP-dependent protein kinase complex
cAMP-dependent protein kinase regulator activity
cell proliferation
fatty acid metabolic process
kinase activity
learning
nucleotide binding
organ morphogenesis
protein amino acid phosphorylation
regulation of protein amino acid phosphorylation
signal transduction
49
H2-Ab1
-1.10585
6.80240
7.90826
0.00097306656
1345392
1425477_x_at
Histocompatibility 2, class II antigen A, beta 1, mRNA (cDNA clone MGC:6297 IMAGE:2651058)
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide antigen
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
early endosome
external side of plasma membrane
Golgi apparatus
immune response
integral to membrane
intracellular
membrane
MHC class II protein complex
multivesicular body
peptide antigen binding
plasma membrane
protein binding
50
Grk5
-1.10743
6.19305
7.30048
0.0051432031
1339828
1449514_at
G protein-coupled receptor kinase 5 (Grk5), mRNA.
ATP binding
G-protein coupled receptor kinase activity
kinase activity
nucleotide binding
protein amino acid phosphorylation
protein kinase activity
protein serine/threonine kinase activity
signal transducer activity
signal transduction
transferase activity
51
Prkar2b
-1.11110
7.23393
8.34503
0.016848462
1372415
1456475_s_at
protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), mRNA.
cAMP binding
cAMP-dependent protein kinase complex
cAMP-dependent protein kinase regulator activity
cell proliferation
fatty acid metabolic process
kinase activity
learning
nucleotide binding
organ morphogenesis
protein amino acid phosphorylation
regulation of protein amino acid phosphorylation
signal transduction
52
-1.11441
4.91783
6.03225
0.0082293457
1364513
1447174_at
Transcribed locus
53
Acaca
-1.11635
9.58950
10.70585
0.0078644728
1354501
1434185_at
acetyl-Coenzyme A carboxylase alpha (Acaca), mRNA.
acetyl-CoA carboxylase activity
ATP binding
biotin binding
biotin carboxylase activity
catalytic activity
cytoplasm
fatty acid biosynthetic process
ligase activity
lipid biosynthetic process
lipid homeostasis
lipid metabolic process
manganese ion binding
metabolic process
metal ion binding
multicellular organismal protein metabolic process
nucleotide binding
protein binding
tissue homeostasis
54
-1.12102
5.74661
6.86763
0.00055010378
1330207
1419033_at
Transcribed locus, strongly similar to XP_001477930.1 PREDICTED: FERM domain containing 7 [Mus musculus]
55
Cdo1
-1.12692
10.12018
11.24709
0.0017236298
1339273
1448842_at
cysteine dioxygenase 1, cytosolic (Cdo1), mRNA.
cysteine dioxygenase activity
cytosol
iron ion binding
L-cysteine catabolic process to taurine
L-cysteine metabolic process
metal ion binding
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
taurine metabolic process
56
9330159F19Rik
-1.12957
6.20515
7.33472
0.0044111187
1369047
1458379_at
RIKEN cDNA 9330159F19 gene, mRNA (cDNA clone IMAGE:8861298)
57
Cxxc5
-1.13205
7.75535
8.88740
0.0017181017
1346671
1431469_a_at
CXXC finger 5 (Cxxc5), mRNA.
cytoplasm
DNA binding
metal ion binding
nucleus
zinc ion binding
58
Cpxm1
-1.15086
6.17671
7.32758
0.00036202459
1339320
1448901_at
carboxypeptidase X 1 (M14 family) (Cpxm1), mRNA.
carboxypeptidase activity
cell adhesion
extracellular region
extracellular space
hydrolase activity
metal ion binding
metallocarboxypeptidase activity
metallopeptidase activity
peptidase activity
proteolysis
zinc ion binding
59
Xpr1
-1.15095
6.87741
8.02836
0.0028395642
1340228
1450130_at
xenotropic and polytropic retrovirus receptor 1 (Xpr1), mRNA.
integral to membrane
membrane
plasma membrane
receptor activity
response to virus
response to virus
60
Erdr1
-1.15330
10.05591
11.20921
0.049327614
1349251
1452406_x_at
erythroid differentiation regulator 1 (Erdr1), mRNA.
61
Cd209g
-1.15806
6.43402
7.59209
0.0056205618
1340086
1449918_at
PREDICTED: CD209g antigen (Cd209g), mRNA.
integral to membrane
membrane
sugar binding
62
Casp3
-1.15976
5.92835
7.08810
0.00017685077
1340027
1449839_at
Caspase 3, mRNA (cDNA clone MGC:46907 IMAGE:4482368)
apoptosis
apoptosis
apoptosis
B cell homeostasis
cell fate commitment
cyclin-dependent protein kinase inhibitor activity
cysteine-type endopeptidase activity
cysteine-type peptidase activity
cytoplasm
DNA fragmentation involved in apoptosis
heart development
hydrolase activity
induction of apoptosis
induction of apoptosis
induction of apoptosis
induction of apoptosis
induction of apoptosis by oxidative stress
induction of apoptosis via death domain receptors
keratinocyte differentiation
negative regulation of activated T cell proliferation
negative regulation of apoptosis
negative regulation of B cell proliferation
negative regulation of cell cycle
negative regulation of cyclin-dependent protein kinase activity
neuron apoptosis
peptidase activity
peptidase activity
peptidase activity
peptidase activity
proteolysis
release of cytochrome c from mitochondria
response to DNA damage stimulus
response to UV
response to UV
response to wounding
sensory perception of sound
T cell homeostasis
63
-1.16427
7.23565
8.39993
0.00029954228
1372388
1455966_s_at
Transcribed locus
64
Clec4a3
-1.16620
5.08407
6.25026
0.0067677331
1351521
1429954_at
C-type lectin domain family 4, member a3 (Clec4a3), mRNA.
integral to membrane
membrane
receptor activity
sugar binding
65
Fscn1
-1.16699
6.05344
7.22043
0.0037455593
1328142
1416515_at
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1), mRNA.
actin binding
actin filament binding
filopodium
protein binding, bridging
66
Rian
-1.17224
6.46988
7.64212
0.0039618965
1342085
1452899_at
MRNA, MBII-343 snoRNA
nucleus
67
Atp6v1a
-1.17269
7.85645
9.02914
5.4384816e-05
1332679
1422508_at
ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), mRNA.
ATP binding
ATP metabolic process
ATP synthesis coupled proton transport
cytosol
hydrogen ion transmembrane transporter activity
hydrogen ion transporting ATP synthase activity, rotational mechanism
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
ion transport
mitochondrion
nucleotide binding
plasma membrane
proton transport
proton-transporting ATPase activity, rotational mechanism
proton-transporting two-sector ATPase complex
proton-transporting two-sector ATPase complex, catalytic domain
proton-transporting V-type ATPase, V1 domain
transport
68
Aldh1a7
-1.17924
7.46230
8.64154
0.036152453
1329842
1418601_at
aldehyde dehydrogenase family 1, subfamily A7 (Aldh1a7), mRNA.
aldehyde dehydrogenase (NAD) activity
cytoplasm
metabolic process
oxidation reduction
oxidoreductase activity
retinal metabolic process
retinoic acid metabolic process
69
Marcks
-1.18120
7.98782
9.16902
0.0035071278
1327729
1415971_at
myristoylated alanine rich protein kinase C substrate (Marcks), mRNA.
actin binding
calmodulin binding
cell cortex
centrosome
cytoplasm
cytoskeleton
germinal vesicle
membrane
protein kinase C binding
70
Acly
-1.18491
9.61227
10.79718
0.036689836
1348104
1439459_x_at
ATP citrate lyase (Acly), mRNA.
acetyl-CoA biosynthetic process
ATP binding
ATP citrate synthase activity
binding
catalytic activity
cellular carbohydrate metabolic process
cytoplasm
intracellular
lipid biosynthetic process
lyase activity
magnesium ion binding
metabolic process
metal ion binding
nucleotide binding
protein binding
succinate-CoA ligase (ADP-forming) activity
transferase activity
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
71
9630033F20Rik
-1.18739
9.11211
10.29951
0.016155043
1357783
1439859_at
RIKEN cDNA 9630033F20 gene (9630033F20Rik), mRNA.
catalytic activity
fructose-2,6-bisphosphate 2-phosphatase activity
hydrolase activity
metabolic process
72
Fgf18
-1.19549
5.41725
6.61274
0.0044434268
1339853
1449545_at
fibroblast growth factor 18 (Fgf18), mRNA.
angiogenesis
chondrocyte development
endochondral ossification
extracellular region
fibroblast growth factor receptor binding
growth factor activity
intramembranous ossification
lung development
ossification
positive regulation of cell proliferation
positive regulation of vascular endothelial growth factor receptor signaling pathway
signal transduction
73
Adcy7
-1.19976
4.28914
5.48889
0.0029695897
1340189
1450065_at
adenylate cyclase 7 (Adcy7), transcript variant 4, mRNA.
activation of adenylate cyclase activity
adenylate cyclase activity
ATP binding
cAMP biosynthetic process
cyclic nucleotide biosynthetic process
integral to membrane
intracellular signaling cascade
lyase activity
magnesium ion binding
membrane
metal ion binding
nucleotide binding
phosphorus-oxygen lyase activity
plasma membrane
74
Kcnq5
-1.22012
4.48108
5.70120
0.020892518
1336159
1427426_at
Voltage-gated potassium channel KCNQ5 (Kcnq5)
integral to membrane
ion channel activity
ion transport
membrane
potassium channel activity
potassium ion binding
potassium ion transport
transport
voltage-gated ion channel activity
voltage-gated potassium channel activity
voltage-gated potassium channel complex
75
Tbx3
-1.23152
5.99345
7.22496
0.024362556
1371329
1437479_x_at
T-box 3 (Tbx3), transcript variant 2, mRNA.
blood vessel development
branching involved in mammary gland duct morphogenesis
cell aging
DNA binding
forelimb morphogenesis
heart looping
heart morphogenesis
in utero embryonic development
limb morphogenesis
limbic system development
mammary gland development
mammary placode formation
mammary placode formation
multicellular organismal development
negative regulation of transcription
negative regulation of transcription, DNA-dependent
nucleus
organ morphogenesis
positive regulation of transcription, DNA-dependent
regulation of cell proliferation
regulation of transcription, DNA-dependent
specification of organ position
transcription
transcription factor activity
transcription repressor activity
76
Vgll3
-1.23250
4.71354
5.94604
0.00083551192
1365660
1453593_at
PREDICTED: vestigial like 3 (Drosophila) (Vgll3), mRNA.
nucleus
regulation of transcription
regulation of transcription, DNA-dependent
transcription
transcription regulator activity
77
Scd2
-1.23398
7.04259
8.27658
0.017924848
1327621
1415823_at
Fatty acid desaturase (Scd3)
endoplasmic reticulum
fatty acid biosynthetic process
integral to membrane
iron ion binding
lipid biosynthetic process
lipid metabolic process
membrane
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
stearoyl-CoA 9-desaturase activity
78
Mmd
-1.25125
8.90339
10.15465
0.00013137363
1333463
1423488_at
monocyte to macrophage differentiation-associated (Mmd), mRNA.
cytolysis
endosome
integral to membrane
lysosome
membrane
receptor activity
79
Tspan2
-1.25798
5.57233
6.83031
0.0068574794
1334291
1424567_at
tetraspanin 2 (Tspan2), mRNA.
integral to membrane
membrane
80
Tkt
-1.25854
11.14908
12.40762
0.006354349
1348090
1439443_x_at
transketolase (Tkt), mRNA.
calcium ion binding
catalytic activity
metabolic process
metal ion binding
regulation of growth
transferase activity
transketolase activity
81
Fscn1
-1.26113
7.66059
8.92172
0.002204768
1343325
1416514_a_at
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1), mRNA.
actin binding
actin filament binding
filopodium
protein binding, bridging
82
-1.26171
7.44652
8.70823
5.5423271e-05
1362970
1445574_at
Transcribed locus
83
-1.27006
5.62003
6.89009
0.00011130469
1356239
1437213_at
Transcribed locus
84
6530401D17Rik
-1.27588
6.03604
7.31192
0.010009851
1341346
1451679_at
RIKEN cDNA 6530401D17 gene (6530401D17Rik), non-coding RNA.
85
Retnla
-1.27777
10.44467
11.72244
0.021562107
1339421
1449015_at
Resistin like alpha, mRNA (cDNA clone MGC:35890 IMAGE:4189285)
extracellular region
hormone activity
86
D330050I23Rik
-1.27889
5.34158
6.62046
0.0025357662
1354564
1434301_at
RIKEN cDNA D330050I23 gene (D330050I23Rik), mRNA.
87
Slc25a1
-1.30386
8.89100
10.19487
0.032205525
1350368
1428190_at
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 (Slc25a1), nuclear gene encoding mitochondrial protein, mRNA.
integral to membrane
membrane
mitochondrial inner membrane
mitochondrion
transport
88
Kcnq5
-1.30428
7.33986
8.64414
0.022270292
1368361
1457587_at
potassium voltage-gated channel, subfamily Q, member 5 (Kcnq5), mRNA.
integral to membrane
ion channel activity
ion transport
membrane
potassium channel activity
potassium ion binding
potassium ion transport
transport
voltage-gated ion channel activity
voltage-gated potassium channel activity
voltage-gated potassium channel complex
89
Dio2
-1.30694
5.66756
6.97449
0.027489775
1330128
1418937_at
deiodinase, iodothyronine, type II (Dio2), mRNA.
hormone biosynthetic process
integral to membrane
membrane
oxidation reduction
oxidoreductase activity
selenium binding
thyroid hormone catabolic process
thyroxine 5'-deiodinase activity
90
Cybb
-1.31512
5.30920
6.62432
0.0025047374
1356037
1436779_at
cytochrome b-245, beta polypeptide (Cybb), mRNA.
cytoplasm
electron carrier activity
electron transport chain
FAD binding
hydrogen peroxide biosynthetic process
integral to membrane
ion channel activity
ion transport
iron ion binding
membrane
metal ion binding
mitochondrion
oxidation reduction
oxidoreductase activity
plasma membrane
transport
voltage-gated ion channel activity
91
Evi2a
-1.31628
5.98662
7.30289
0.0012303923
1348619
1450241_a_at
ecotropic viral integration site 2a (Evi2a), transcript variant 2, mRNA.
integral to membrane
membrane
92
Bpnt1
-1.33936
6.66312
8.00248
1.9084413e-05
1339578
1449211_at
bisphosphate 3'-nucleotidase 1 (Bpnt1), mRNA.
3'(2'),5'-bisphosphate nucleotidase activity
hydrolase activity
inositol or phosphatidylinositol phosphatase activity
lithium ion binding
magnesium ion binding
metal ion binding
93
Cd48
-1.34077
5.01426
6.35503
0.0024981736
1336073
1427301_at
CD48 antigen (Cd48), mRNA.
anchored to membrane
eukaryotic cell surface binding
external side of plasma membrane
membrane
plasma membrane
protein binding
response to protein stimulus
signal transduction
T cell activation
94
Mcpt4
-1.34092
6.85196
8.19288
0.0044352497
1345622
1425967_a_at
mast cell protease 4 (Mcpt4), mRNA.
hydrolase activity
intracellular
peptidase activity
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
95
Tkt
-1.34317
10.04487
11.38804
0.0054799905
1340882
1451015_at
transketolase (Tkt), mRNA.
calcium ion binding
catalytic activity
metabolic process
metal ion binding
regulation of growth
transferase activity
transketolase activity
96
-1.34761
6.76076
8.10837
0.0064046775
1357038
1438720_at
Transcribed locus
97
Fasn
-1.35132
11.21748
12.56880
0.011395055
1333715
1423828_at
fatty acid synthase (Fasn), mRNA.
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
3-oxoacyl-[acyl-carrier-protein] reductase activity
3-oxoacyl-[acyl-carrier-protein] synthase activity
[acyl-carrier-protein] S-acetyltransferase activity
[acyl-carrier-protein] S-malonyltransferase activity
acyl carrier activity
acyltransferase activity
binding
biosynthetic process
catalytic activity
cofactor binding
cytoplasm
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
fatty acid biosynthetic process
fatty-acid synthase activity
glycogen granule
hydrolase activity
hydrolase activity, acting on ester bonds
lipid biosynthetic process
lyase activity
metabolic process
oleoyl-[acyl-carrier-protein] hydrolase activity
oxidation reduction
oxidoreductase activity
phosphopantetheine binding
transferase activity
zinc ion binding
98
St8sia4
-1.35715
5.96965
7.32680
0.0051116231
1343807
1419186_a_at
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (St8sia4), transcript variant 1, mRNA.
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
Golgi apparatus
integral to Golgi membrane
integral to membrane
membrane
protein amino acid glycosylation
sialyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
99
Tusc5
-1.38385
7.57417
8.95801
0.0076936342
1358895
1441096_at
tumor suppressor candidate 5 (Tusc5), mRNA.
integral to membrane
membrane
response to biotic stimulus
100
-1.38542
6.02836
7.41378
0.0031168307
1360916
1443353_at
ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus]
101
Iqgap2
-1.39627
6.60337
7.99964
0.0054191919
1354344
1433885_at
IQ motif containing GTPase activating protein 2 (Iqgap2), mRNA.
calmodulin binding
GTPase activator activity
intracellular
protein binding
regulation of small GTPase mediated signal transduction
102
Sfrp2
-1.40292
6.91090
8.31382
0.010551215
1338760
1448201_at
secreted frizzled-related protein 2 (Sfrp2), mRNA.
anterior/posterior pattern formation
cell differentiation
cellular response to extracellular stimulus
extracellular region
multicellular organismal development
somitogenesis
Wnt receptor signaling pathway
103
Agpat2
-1.40910
9.08096
10.49006
0.018493841
1350720
1428821_at
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), mRNA
1-acylglycerol-3-phosphate O-acyltransferase activity
acyltransferase activity
endoplasmic reticulum
integral to membrane
membrane
metabolic process
phospholipid biosynthetic process
transferase activity
104
Acly
-1.41204
9.86636
11.27840
0.018062669
1341334
1451666_at
ATP citrate lyase (Acly), mRNA.
acetyl-CoA biosynthetic process
ATP binding
ATP citrate synthase activity
binding
catalytic activity
cellular carbohydrate metabolic process
cytoplasm
intracellular
lipid biosynthetic process
lyase activity
magnesium ion binding
metabolic process
metal ion binding
nucleotide binding
protein binding
succinate-CoA ligase (ADP-forming) activity
transferase activity
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
105
Adrb3
-1.42741
5.62155
7.04895
0.00096338252
1331990
1421555_at
adrenergic receptor, beta 3 (Adrb3), mRNA.
activation of adenylate cyclase activity by G-protein signaling pathway
adrenoceptor activity
beta-3 adrenergic receptor binding
beta-adrenergic receptor activity
brown fat cell differentiation
diet induced thermogenesis
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
heat generation
integral to membrane
membrane
membrane fraction
negative regulation of multicellular organism growth
plasma membrane
receptor activity
response to cold
signal transducer activity
signal transduction
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
106
Pparg
-1.44818
7.29862
8.74680
0.0025828068
1344152
1420715_a_at
peroxisome proliferator activated receptor gamma (Pparg), transcript variant 2, mRNA.
arachidonic acid binding
brown fat cell differentiation
cell fate commitment
chromatin binding
cytosol
DNA binding
DNA binding
epithelial cell differentiation
fat cell differentiation
fat cell differentiation
inflammatory response
ligand-dependent nuclear receptor activity
long-chain fatty acid transport
metal ion binding
negative regulation of cell proliferation
negative regulation of cytokine production
negative regulation of transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-dependent
nucleus
placenta development
positive regulation of fat cell differentiation
positive regulation of fat cell differentiation
positive regulation of transcription
positive regulation of transcription from RNA polymerase II promoter
protein binding
receptor activity
regulation of fat cell differentiation
regulation of fat cell differentiation
regulation of transcription
regulation of transcription, DNA-dependent
response to lipid
sequence-specific DNA binding
steroid hormone receptor activity
transcription
transcription activator activity
transcription factor activity
transcription repressor activity
transcription repressor activity
transcriptional repressor complex
white fat cell differentiation
white fat cell differentiation
zinc ion binding
107
Klra9
-1.45296
5.93247
7.38542
0.0072815974
1345371
1425436_x_at
killer cell lectin-like receptor subfamily A, member 9 (Klra9), mRNA.
plasma membrane
receptor activity
sugar binding
108
Nrg4
-1.45825
6.03043
7.48869
0.02172261
1332082
1421681_at
neuregulin 4 (Nrg4), mRNA.
extracellular region
growth factor activity
integral to membrane
membrane
plasma membrane
109
Cxcr4
-1.49151
5.28352
6.77503
0.011811138
1339165
1448710_at
chemokine (C-X-C motif) receptor 4 (Cxcr4), mRNA.
ameboidal cell migration
brain development
C-C chemokine receptor activity
C-X-C chemokine receptor activity
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
germ cell development
germ cell migration
growth cone
integral to membrane
membrane
motor axon guidance
nervous system development
neuron migration
organ morphogenesis
patterning of blood vessels
plasma membrane
receptor activity
regulation of cell migration
regulation of cell migration
signal transducer activity
signal transduction
T cell proliferation
110
Myct1
-1.50921
4.68398
6.19319
0.0069344917
1335414
1426433_at
myc target 1 (Myct1), mRNA.
integral to membrane
membrane
nucleus
111
2210015D19Rik
-1.53532
7.61870
9.15402
0.00025841882
1356810
1438285_at
PREDICTED: Mus musculus RIKEN cDNA 2210015D19 gene, transcript variant 2 (2210015D19Rik), mRNA
112
Sertad4
-1.54211
5.39034
6.93245
0.0025980339
1366550
1454877_at
SERTA domain containing 4 (Sertad4), mRNA.
113
Myct1
-1.54920
6.18984
7.73903
0.0046209341
1371969
1447584_s_at
myc target 1 (Myct1), mRNA.
integral to membrane
membrane
nucleus
114
Gpr120
-1.56283
4.40725
5.97008
0.02976068
1357453
1439489_at
G protein-coupled receptor 120 (Gpr120), mRNA.
endocytic vesicle
fatty acid binding
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
hormone secretion
integral to membrane
lipid binding
membrane
plasma membrane
receptor activity
signal transducer activity
signal transduction
115
Ptger3
-1.58957
5.03714
6.62670
0.0038734357
1348652
1450344_a_at
prostaglandin E receptor 3 (subtype EP3) (Ptger3), mRNA.
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
bicarbonate transport
diuresis
elevation of cytosolic calcium ion concentration
fever
fever
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
G-protein signaling, coupled to cAMP nucleotide second messenger
integral to membrane
membrane
plasma membrane
prostaglandin E receptor activity
prostaglandin E receptor activity
prostaglandin receptor activity
protein binding
receptor activity
signal transducer activity
signal transduction
116
Car3
-1.60246
5.48391
7.08637
0.02824509
1365656
1453588_at
Carbonic anhydrase 3, mRNA (cDNA clone MGC:18583 IMAGE:4195712)
carbonate dehydratase activity
cytoplasm
lyase activity
metal ion binding
nickel ion binding
one-carbon metabolic process
zinc ion binding
117
1110020P15Rik
-1.66781
9.72731
11.39511
0.0012940561
1337510
1434340_at
RIKEN cDNA 1110020P15 gene, mRNA (cDNA clone MGC:37480 IMAGE:4984172)
electron transport chain
membrane
mitochondrial electron transport, ubiquinol to cytochrome c
mitochondrial envelope
mitochondrial inner membrane
mitochondrion
respiratory chain
transport
ubiquinol-cytochrome-c reductase activity
118
Cebpa
-1.67010
9.40938
11.07948
5.8370473e-06
1330167
1418982_at
CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa), mRNA.
brown fat cell differentiation
cell maturation
cytokine-mediated signaling pathway
DNA binding
embryonic placenta development
fat cell differentiation
liver development
lung development
macrophage differentiation
mitochondrion organization
myeloid cell differentiation
negative regulation of cell proliferation
negative regulation of transcription from RNA polymerase II promoter
nucleus
positive regulation of specific transcription from RNA polymerase II promoter
positive regulation of transcription
promoter binding
protein binding
protein dimerization activity
protein homodimerization activity
regulation of cell proliferation
regulation of transcription, DNA-dependent
RNA polymerase II transcription factor activity, enhancer binding
sequence-specific DNA binding
specific RNA polymerase II transcription factor activity
transcription
transcription factor activity
transcription factor complex
urea cycle
119
Ppp1r3b
-1.68500
5.71157
7.39657
0.049937484
1355930
1436590_at
protein phosphatase 1, regulatory (inhibitor) subunit 3B (Ppp1r3b), mRNA.
carbohydrate metabolic process
glycogen metabolic process
120
Acly
-1.69082
8.62603
10.31685
0.016002772
1334817
1425326_at
ATP citrate lyase (Acly), mRNA.
acetyl-CoA biosynthetic process
ATP binding
ATP citrate synthase activity
binding
catalytic activity
cellular carbohydrate metabolic process
cytoplasm
intracellular
lipid biosynthetic process
lyase activity
magnesium ion binding
metabolic process
metal ion binding
nucleotide binding
protein binding
succinate-CoA ligase (ADP-forming) activity
transferase activity
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
121
Aplnr
-1.72043
7.75029
9.47072
0.0014878131
1347891
1438651_a_at
apelin receptor (Aplnr), mRNA.
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
integral to membrane
membrane
plasma membrane
receptor activity
signal transducer activity
signal transduction
122
Scd2
-1.76015
6.62797
8.38812
0.00086884444
1327622
1415824_at
stearoyl-Coenzyme A desaturase 2 (Scd2), mRNA.
endoplasmic reticulum
fatty acid biosynthetic process
integral to membrane
iron ion binding
lipid biosynthetic process
lipid metabolic process
membrane
oxidation reduction
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
stearoyl-CoA 9-desaturase activity
123
H2-Aa
-1.77813
7.91292
9.69104
0.00031471617
1349261
1452431_s_at
Histocompatibility 2, class II antigen A, alpha, mRNA (cDNA clone MGC:25391 IMAGE:3670758)
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide antigen
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
external side of plasma membrane
immune response
integral to membrane
lysosome
membrane
MHC class II protein complex
peptide antigen binding
plasma membrane
positive regulation of T cell differentiation
protein binding
124
Mosc1
-1.80239
4.23064
6.03303
0.0027802828
1336527
1428005_at
MOCO sulphurase C-terminal domain containing 1 (Mosc1), mRNA.
catalytic activity
mitochondrial inner membrane
mitochondrion
molybdenum ion binding
oxidation reduction
oxidoreductase activity
pyridoxal phosphate binding
125
Rasd2
-1.86659
6.46497
8.33157
0.043595931
1336105
1427343_at
RASD family, member 2, mRNA (cDNA clone IMAGE:4988981)
GTP binding
intracellular
locomotory behavior
membrane
nucleotide binding
small GTPase mediated signal transduction
126
Elovl6
-1.92266
7.07168
8.99434
0.028053415
1328866
1417403_at
ELOVL family member 6, elongation of long chain fatty acids (yeast) (Elovl6), mRNA.
endoplasmic reticulum
fatty acid biosynthetic process
fatty acid elongation
integral to endoplasmic reticulum membrane
integral to membrane
lipid biosynthetic process
membrane
mitochondrion
transferase activity, transferring acyl groups other than amino-acyl groups
127
Elovl6
-1.95709
7.64029
9.59738
0.016719341
1328867
1417404_at
ELOVL family member 6, elongation of long chain fatty acids (yeast) (Elovl6), mRNA.
endoplasmic reticulum
fatty acid biosynthetic process
fatty acid elongation
integral to endoplasmic reticulum membrane
integral to membrane
lipid biosynthetic process
membrane
mitochondrion
transferase activity, transferring acyl groups other than amino-acyl groups
128
Car3
-2.01063
8.31320
10.32382
0.021204072
1370950
1430584_s_at
Carbonic anhydrase 3, mRNA (cDNA clone MGC:18583 IMAGE:4195712)
carbonate dehydratase activity
cytoplasm
lyase activity
metal ion binding
nickel ion binding
one-carbon metabolic process
zinc ion binding
129
Adrb3
-2.39460
7.08551
9.48011
0.00074486461
1342546
1455918_at
adrenergic receptor, beta 3
130
E130009J12Rik
-3.16212
3.83455
6.99668
0.00527146
1357529
1439575_at
RIKEN cDNA E130009J12 gene (E130009J12Rik), mRNA.