Muscle: EG003.2
(T2-) Stat5MKO-GH vs WT-GH --- fold changes < 2X and p-Value<0.05.
This mAdb-derived analysis report compares two groups of samples (A and B) using the paired t-test followed by a fold-change test with the threshold values listed above. The t-test is only done if are at least two samples/condition. It performs fold-change thresholding in either case. The mean A and mean B values are shown as log2 values in the following table as A Mean and B Mean. If there are not enough samples in either condition A or condition B, it only compares the fold-change (mean A/mean B) computed as the difference between the log2 means shown as A-B Mean Difference in this report - see Data Analysis Methods for more discussion. If the t-test is performed, the p-Value is reported as A-B p-Value. Individual sample expression values are reported as the RMA normalized values not using the log2. The tests, thresholding and mAdb Retrieval Report were generated on the mAdb system for the GSP data and subsequently converted to this Web page.
Clicking on the table entries for Gene, Well ID, and Feature ID
will go to the GeneCard, mAdb Feature Report, and Affymetrix probe database Web page
for that entry. The genes are sorted by A-B Mean Difference with:
(A) Samples[Stat5MKO-GH]: EG003.2-04, EG003.2-05, EG003.2-06
(B) Samples[WT-GH]: EG003.2-01, EG003.2-02, EG003.2-03.
Row | A | A | A | B | B | B | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Row | Gene | A-B Mean Difference | A Mean (Stat5MKO-GH) | B Mean (WT-GH) | A-B p-Value | Well ID | Feature ID | Description | EG003.2-01.Muscle.WT.4038WT.noStim | EG003.2-02.Muscle.WT.4060WT.noStim | EG003.2-03.Muscle.WT.4063WT.noStim | EG003.2-04.Muscle.Stat5MKO.4035KO.noStim | EG003.2-05.Muscle.Stat5MKO.4036KO.noStim | EG003.2-06.Muscle.Stat5MKO.4042KO.noStim | Gene Ontology Terms |
1 | Ak3l1 | -1.05022 | 6.48540 | 7.53562 | 0.0093021397 | 1332186 | 1421830_at | adenylate kinase 3-like 1 (Ak3l1), nuclear gene encoding mitochondrial protein, mRNA. | 113.1034 | 81.5462 | 77.9860 | 162.8186 | 218.5802 | 179.4852 | |
2 | Mustn1 | -1.06881 | 10.41685 | 11.48566 | 0.018573107 | 1335990 | 1427201_at | musculoskeletal, embryonic nuclear protein 1 (Mustn1), mRNA. | 1112.3910 | 1549.3411 | 1482.3400 | 3852.3579 | 2425.2815 | 2524.0403 | nucleus |
3 | Tnfaip2 | -1.08163 | 10.37704 | 11.45867 | 0.040723537 | 1347930 | 1438855_x_at | tumor necrosis factor, alpha-induced protein 2 | 1937.2358 | 1153.9852 | 1051.9975 | 2594.0235 | 3370.5477 | 2549.9669 | |
4 | Serpina1c | -1.14894 | 4.84929 | 5.99823 | 0.010746921 | 1339138 | 1448680_at | serine (or cysteine) peptidase inhibitor, clade A, member 1C (Serpina1c), mRNA. | 35.0984 | 23.1433 | 29.4871 | 67.2878 | 68.1489 | 56.9569 | |
5 | Stat3 | -1.15172 | 9.22101 | 10.37272 | 0.0053308228 | 1343080 | 1460700_at | signal transducer and activator of transcription 3 (Stat3), transcript variant 3, mRNA. | 563.5964 | 511.8688 | 736.6675 | 1215.0369 | 1560.5489 | 1229.2415 | |
6 | Serpinb1a | -1.22031 | 6.14677 | 7.36708 | 0.00034890631 | 1327998 | 1416318_at | serine (or cysteine) peptidase inhibitor, clade B, member 1a (Serpinb1a), mRNA. | 74.1940 | 72.3079 | 66.3027 | 182.2095 | 154.0949 | 160.2428 | |
7 | Ak3l1 | -1.22369 | 7.22808 | 8.45177 | 0.040083447 | 1348663 | 1450387_s_at | adenylate kinase 3-like 1 (Ak3l1), nuclear gene encoding mitochondrial protein, mRNA. | 218.2075 | 134.3381 | 114.9569 | 315.7167 | 362.3709 | 375.1926 | |
8 | Sln | -1.23119 | 7.68650 | 8.91769 | 0.0054222097 | 1331506 | 1420884_at | sarcolipin (Sln), mRNA. | 178.8438 | 211.0753 | 231.5755 | 587.5316 | 395.1282 | 487.1988 | |
9 | -1.24487 | 7.35232 | 8.59718 | 0.0037471724 | 1367914 | 1457102_at | Transcribed locus | 195.5695 | 138.2218 | 161.4077 | 393.0408 | 457.7161 | 322.8464 | ||
10 | Gamt | -1.24753 | 9.20233 | 10.44986 | 0.0052749455 | 1332719 | 1422558_at | guanidinoacetate methyltransferase (Gamt), mRNA. | 517.6892 | 585.7949 | 674.0960 | 1349.6060 | 1406.0643 | 1441.9590 | |
11 | Tnfaip2 | -1.34592 | 9.55423 | 10.90015 | 0.019383957 | 1327963 | 1416273_at | tumor necrosis factor, alpha-induced protein 2 (Tnfaip2), mRNA. | 1091.3115 | 612.3186 | 635.9214 | 1565.4321 | 2320.3607 | 1921.4254 | |
12 | Fgfbp1 | -1.41894 | 5.16466 | 6.58361 | 0.0011928135 | 1330250 | 1419086_at | fibroblast growth factor binding protein 1 (Fgfbp1), mRNA. | 30.1154 | 38.2075 | 40.1069 | 111.3767 | 89.7235 | 88.2856 | |
13 | -1.43316 | 7.74730 | 9.18046 | 0.020322115 | 1365310 | 1453119_at | Transcribed locus | 210.8462 | 215.7630 | 218.0549 | 459.4518 | 757.4940 | 561.2626 | ||
14 | 1200009I06Rik | -2.05051 | 7.53553 | 9.58603 | 0.016057694 | 1370826 | 1428420_a_at | RIKEN cDNA 1200009I06 gene (1200009I06Rik), mRNA. | 208.0928 | 181.2786 | 169.2994 | 576.1519 | 675.4474 | 1166.6011 | |
15 | Myh7 | -2.16573 | 7.41775 | 9.58347 | 0.049555307 | 1348252 | 1448554_s_at | myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7), mRNA. | 98.3841 | 328.7075 | 154.5816 | 769.0408 | 813.4041 | 721.9121 | |
16 | Tpm3 | -2.38939 | 8.57935 | 10.96874 | 0.035580778 | 1340138 | 1449997_at | Tropomyosin 3, gamma, mRNA (cDNA clone MGC:36031 IMAGE:4502880) | 249.1013 | 748.7493 | 300.0638 | 1856.5197 | 1897.4333 | 2285.0254 | |
17 | Tnni1 | -2.40297 | 7.86608 | 10.26905 | 0.028790526 | 1348770 | 1450813_a_at | troponin I, skeletal, slow 1 (Tnni1), transcript variant 2, mRNA. | 146.8151 | 436.8152 | 198.0208 | 1158.1453 | 1100.0280 | 1474.7292 | |
18 | -2.43608 | 5.03578 | 7.47186 | 0.021004874 | 1368821 | 1458115_at | Transcribed locus | 31.6866 | 34.7647 | 32.0440 | 106.5041 | 232.3178 | 226.1078 | ||
19 | Tnnc1 | -2.54042 | 8.50746 | 11.04788 | 0.040945566 | 1329660 | 1418370_at | troponin C, cardiac/slow skeletal (Tnnc1), mRNA. | 269.9078 | 781.6517 | 228.4423 | 2008.4111 | 1945.6615 | 2428.3396 |
This Web page was derived in collaboration with GSP consortium members.
Home: jak-stat.nih.gov
Home: Jak-Stat Prospector
Revised: Mon Sep 28 13:56:56 EDT 2009