A 1 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen A 2 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen A 3 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen B 4 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen B 5 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen B 6 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen The input data set contained 45101 genes The filtered output data set contains 502 genes 35579 gene rows removed by Include where A-B T-test p-value (two tailed) <= 0.05 9020 gene rows removed by Include where A-B Mean Difference >= 1 A A A B B B 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen A-B p-Value A-B Mean Difference A Mean B Mean Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 801.1414 853.2240 850.5619 313.8703 278.6790 216.3908 0.0074610457 1.64700 9.70499 8.05799 1350144 AFFX-DapX-M_at IPA B. subtilis GEN=dapB, jojF DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2020-2580 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA- 1230.4274 1235.7222 1185.5707 313.7877 282.7195 231.2158 0.0030481436 2.15249 10.24915 8.09666 1350142 AFFX-DapX-3_at IPA B. subtilis GEN=jojG DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2684-3130 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carbox 75.5921 75.6916 79.0074 38.5685 30.1528 32.0137 0.006235222 1.20065 6.26205 5.06140 1350147 AFFX-LysX-M_at IPA B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 720-990 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). 235.9080 284.5286 290.8588 93.6724 78.6248 77.9344 0.00020637066 1.69601 8.07290 6.37688 1350145 AFFX-LysX-3_at IPA B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 1061-1343 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). 59.2287 57.7493 62.6384 28.0724 28.9784 28.9830 0.0001829166 1.06127 5.90298 4.84171 1350151 AFFX-PheX-M_at IPA B. subtilis GEN=pheA DB_XREF=gb:M24537.1 NOTE=SIF corresponding to nucleotides 2437-2828 of gb:M24537.1 DEF=Bacillus subtillis sporulation protein (spoOB), GTP-binding protein (obg), phenylalanine biosynthesis associated protein (pheB), and monofuncti 129.6274 121.9468 122.9945 67.8354 57.9767 48.7622 0.012339394 1.11391 6.96359 5.84969 1350154 AFFX-ThrX-M_at IPA B. subtilis GEN=thrC, thrB DB_XREF=gb:X04603.1 NOTE=SIF corresponding to nucleotides 995-1562 of gb:X04603.1, not 100% identical DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectivel 591.8521 591.8204 623.2756 198.0631 173.2261 160.0656 0.001380804 1.77100 9.23395 7.46295 1350152 AFFX-ThrX-3_at IPA B. subtilis GEN=thrB DB_XREF=gb:X04603.1 NOTE=SIF corresponding to nucleotides 1689-2151 of gb:X04603.1 DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively). 240.0350 236.1312 269.3019 142.6960 122.4563 92.2594 0.01975214 1.08103 7.95454 6.87352 1350163 AFFX-r2-Bs-dap-5_at IPA 758.4699 829.4598 767.0330 289.8911 234.9433 167.2898 0.013929009 1.80146 9.61537 7.81391 1350164 AFFX-r2-Bs-dap-M_at IPA 1618.9296 1732.5477 1701.7583 458.7377 358.8226 318.0669 0.003997732 2.17016 10.71744 8.54728 1350162 AFFX-r2-Bs-dap-3_at IPA 56.7597 74.1617 88.6926 32.6149 21.5164 25.0545 0.0046491776 1.46944 6.17005 4.70061 1350166 AFFX-r2-Bs-lys-5_at IPA 80.6100 87.4554 89.5790 27.5300 23.6938 21.8166 0.00062609227 1.82391 6.42282 4.59891 1350167 AFFX-r2-Bs-lys-M_at IPA 108.1203 149.7591 123.4531 35.2576 35.3252 34.8098 0.0053538023 1.84230 6.97694 5.13464 1350165 AFFX-r2-Bs-lys-3_at IPA 62.2146 79.5580 71.2665 35.2576 29.0165 24.8733 0.0030904974 1.26436 6.14276 4.87840 1350169 AFFX-r2-Bs-phe-5_at IPA 125.8205 112.5800 119.9266 44.7214 39.4096 36.0316 0.00059207034 1.58049 6.89868 5.31819 1350170 AFFX-r2-Bs-phe-M_at IPA 255.7814 445.3617 330.4077 150.3424 116.6973 87.3953 0.0089168869 1.53916 8.38857 6.84941 1350168 AFFX-r2-Bs-phe-3_at IPA 677.5051 711.9807 688.4113 202.5408 211.5588 178.5492 0.00078623965 1.81325 9.43564 7.62239 1350180 AFFX-r2-Bs-thr-3_s_at IPA 3016.4046 3036.3917 2964.8620 1332.5964 1340.1888 1336.4467 3.4424281e-05 1.16936 11.55350 10.38414 1350161 AFFX-MURINE_b1_at IPA M. musculus GEN=b1 DB_XREF=gb:U01310.1 NOTE=SIF corresponding to nucleotides 5-75 of gb:U01310.1 DEF=Mus musculus C57 Black6 BC1 scRNA. 1523.0491 1576.7918 1560.4356 390.0408 477.4949 303.1974 0.0084018217 2.01744 10.60109 8.58365 1327679 1415899_at 8 C2-D1|8 38.6 cM chr8:87500883-87501393 8 C3 UGA Mm.1167 16477 Junb Jun-B oncogene, mRNA (cDNA clone MGC:6021 IMAGE:3592704) GATA3 participate in activating the Th2 cytokine genes expression cellular process;; decidualization;; DNA binding;; embryonic process involved in female pregnancy;; in utero embryonic development;; labyrinthine layer blood vessel development;; nucleus;; positive regulation of cell differentiation;; protein dimerization activity;; regulation of cell cycle;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; trophectodermal cell differentiation;; trophectodermal cell differentiation;; vasculogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multi-organism process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; embryonic development;; female pregnancy;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; reproductive process in a multicellular organism 503.5929 520.5099 516.2546 176.3360 171.2954 133.1809 0.0052767493 1.69069 9.00394 7.31326 1343221 1416065_a_at 8 chr8:11611620-11611723 8 A1.1 chr8:11611582-11635689 8 A1.1 RSQ Mm.12459 NM_133971 1 1 102334 Ankrd10 ankyrin repeat domain 10 (Ankrd10), mRNA. 371.1123 341.8106 348.9457 133.9404 151.6357 144.8781 8.3593405e-05 1.30367 8.46654 7.16287 1327807 1416081_at 8 chr8:81863358-81867687 8 C2 chr8:81862293-81923367 8 C2 RSQ Mm.223717 NM_008539 1 1 17125 Smad1 MAD homolog 1 (Drosophila) (Smad1), mRNA. CTCF: First Multivalent Nuclear Factor TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] BMP signaling pathway;; BMP signaling pathway;; BMP signaling pathway;; cytoplasm;; gamete generation;; hindbrain development;; homeostatic process;; inflammatory response;; intracellular;; MAPKKK cascade;; mesodermal cell fate commitment;; midbrain development;; negative regulation of cell proliferation;; nucleus;; osteoblast fate commitment;; positive regulation of gene expression;; positive regulation of osteoblast differentiation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; RNA polymerase II transcription factor activity;; transcription;; transcription factor activity;; transcription factor complex;; transforming growth factor beta receptor signaling pathway cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; nitrogen compound metabolic process;; ossification;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive process;; response to external stimulus;; response to stress;; sexual reproduction;; tissue remodeling 3446.3923 3507.7425 3435.3537 738.2315 711.9717 643.7601 0.00049567336 2.31315 11.75781 9.44466 1327844 1416125_at 17 13.0 cM chr17:28536264-28536617 17 A3.3 chr17:28536039-28623057 17 A3.3 RSQ Mm.276405 NM_010220 1 1 14229 Fkbp5 FK506 binding protein 5 (Fkbp5), mRNA. binding;; cytoplasm;; isomerase activity;; nucleus;; peptidyl-prolyl cis-trans isomerase activity;; protein binding;; protein folding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1102.7307 1105.3054 1109.2005 376.9413 413.3499 389.1086 0.00065326466 1.49298 10.11080 8.61782 1327847 1416129_at 4 chr4:150242409-150242794 4 E2 chr4:150229199-150242989 4 E2 RSQ Mm.318841 NM_133753 1 1 74155 RP23-272N19.4 Errfi1 ERBB receptor feedback inhibitor 1 (Errfi1), mRNA. cytoplasm;; cytosol;; protein binding;; receptor activity;; stress-activated protein kinase signaling pathway cell;; cell part cell part;; intracellular;; intracellular part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular response to stimulus;; regulation of biological process;; regulation of cellular process;; response to stress 2173.3450 2201.8324 2177.4033 692.9852 770.9827 834.4657 0.0024946744 1.51555 11.09286 9.57731 1327922 1416225_at 3 71.2 cM chr3:137949846-137953543 3 G3 chr3:137940608-137953655 3 G3 RSQ Mm.2409 NM_007409 1 1 11522 Adh1 alcohol dehydrogenase 1 (class I) (Adh1), mRNA. 1- and 2-Methylnaphthalene degradation;; 3-Chloroacrylic acid degradation;; Drug metabolism - cytochrome P450;; Fatty acid metabolism;; Glycolysis / Gluconeogenesis;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:mmu00071] Metabolism; Amino Acid Metabolism; Tyrosine metabolism [PATH:mmu00350] Metabolism; Metabolism of Cofactors and Vitamins; Retinol metabolism [PATH:mmu00830] Metabolism; Xenobiotics;; Metabolism of xenobiotics by cytochrome P450;; Retinol metabolism;; Tyrosine metabolism alcohol dehydrogenase (NAD) activity;; alcohol dehydrogenase (NAD) activity;; behavioral response to ethanol;; cytoplasm;; ethanol catabolic process;; ethanol catabolic process;; intracellular;; metal ion binding;; mitochondrion;; oxidation reduction;; oxidoreductase activity;; protein homodimerization activity;; response to retinoic acid;; response to steroid hormone stimulus;; response to testosterone stimulus;; retinoic acid metabolic process;; retinoic acid metabolic process;; retinoid metabolic process;; retinol metabolic process;; retinol metabolic process;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity;; protein binding biological regulation;; cellular process;; metabolic process;; multicellular organismal process;; response to stimulus adult behavior;; alcohol metabolic process;; behavior;; catabolic process;; cellular metabolic process;; hormone metabolic process;; oxidation reduction;; primary metabolic process;; regulation of biological quality;; response to chemical stimulus;; response to endogenous stimulus;; response to external stimulus;; secondary metabolic process 6338.8642 6196.7090 6267.6941 669.4725 1509.8063 737.5304 0.017096455 2.78914 12.61367 9.82453 1327943 1416250_at 1 71.0 cM chr1:135973961-135975525 1 E4 chr1:135971441-135975732 1 E4 RSQ Mm.392646 NM_007570 1 1 12227 Btg2 B-cell translocation gene 2, anti-proliferative (Btg2), mRNA. BTG family proteins and cell cycle regulation anterior/posterior pattern formation;; negative regulation of apoptosis;; neuron differentiation;; protein amino acid methylation;; protein binding;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; transcription binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to stress 963.3854 916.9217 957.6589 459.9460 380.5199 303.6338 0.015278896 1.33088 9.88533 8.55445 1328081 1416431_at 18 chr18:67561958-67562376 18 E1 chr18:67550384-67562403 18 E1 RSQ Mm.181860 NM_026473 1 1 67951 Tubb6 tubulin, beta 6 (Tubb6), mRNA. Gap junction CLASS Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] GTP binding;; GTPase activity;; microtubule;; microtubule-based movement;; microtubule-based process;; nucleotide binding;; protein complex;; protein polymerization;; structural molecule activity cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity hydrolase activity;; nucleotide binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process cellular component assembly;; cellular macromolecular complex subunit organization;; macromolecular complex subunit organization;; microtubule-based process;; protein complex biogenesis 2725.9996 2806.0964 2673.9977 416.5916 379.8765 532.6616 0.0025947609 2.64092 11.41723 8.77632 1328194 1416576_at 11 chr11:117827755-117827967 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 3433.7399 3387.4116 3384.3741 1196.2037 1610.0241 1432.8699 0.0092251192 1.27813 11.73207 10.45394 1343341 1416600_a_at 16 C4|16 62.0 cM chr16:92392241-92392607 16 C4 UGA Mm.265744 54720 Rcan1 Regulator of calcineurin 1, mRNA (cDNA clone MGC:19348 IMAGE:4236038) calcium-mediated signaling;; cytoplasm;; nucleus;; regulation of phosphoprotein phosphatase activity;; skeletal muscle fiber development cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cell communication;; cellular developmental process;; cellular metabolic process;; multicellular organismal development;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 1441.1380 1491.7205 1502.2351 568.4736 685.9574 693.4115 0.0046683857 1.19272 10.52955 9.33683 1343342 1416601_a_at 16 62.0 cM chr16:92393721-92397682 16 C4 chr16:92392197-92400322 16 C4 RSQ Mm.265744 NM_019466 2 1 54720 Rcan1 regulator of calcineurin 1 (Rcan1), transcript variant 2, mRNA. calcium-mediated signaling;; cytoplasm;; nucleus;; regulation of phosphoprotein phosphatase activity;; skeletal muscle fiber development cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cell communication;; cellular developmental process;; cellular metabolic process;; multicellular organismal development;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 5921.1519 5934.3151 5847.0438 1668.9639 1584.6678 1974.9297 0.0028229678 1.76591 12.52667 10.76076 1328407 1416840_at X chrX:10296247-10296743 X A1.1 chrX:10294619-10296823 X A1.1 RSQ Mm.29429 NM_026524 1 1 68041 RP23-130J1.1 Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) (Mid1ip1), mRNA. cytoplasm;; microtubule;; microtubule cytoskeleton;; negative regulation of microtubule depolymerization;; nucleus;; protein binding;; protein C-terminus binding cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process cellular component disassembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; microtubule-based process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process 694.7075 689.8186 680.7294 292.9109 344.5294 265.9390 0.0078322303 1.20117 9.42709 8.22592 1343415 1416983_s_at 3 chr3:52153576-52154004 3 C UG5 Mm.395558 Transcribed locus 4687.2495 4806.2947 4760.1034 280.4741 281.0701 277.9745 1.2099936e-07 4.08556 12.21400 8.12844 1328588 1417065_at 18 16.0 cM chr18:35024067-35024594 18 B1 chr18:35020860-35024610 18 B1 RSQ Mm.181959 NM_007913 1 1 13653 Egr1 early growth response 1 (Egr1), mRNA. Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway Prion diseases CLASS Human Diseases; Neurodegenerative Diseases; Prion diseases [PATH:mmu05020] DNA binding;; intracellular;; metal ion binding;; negative regulation of transcription from RNA polymerase II promoter;; nucleic acid binding;; nucleus;; nucleus;; regulation of transcription, DNA-dependent;; response to protein stimulus;; T cell differentiation;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cellular developmental process;; cellular metabolic process;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus 1405.0368 1518.9285 1415.4589 563.8303 607.9311 489.9297 0.0015519966 1.38966 10.49743 9.10777 1343431 1417068_a_at 2 chr2:167801006-167802371 2 H3 chr2:167757826-167804885 2 H3 RSQ Mm.277916 NM_011201 1 1 19246 RP23-58A8.1 Ptpn1 protein tyrosine phosphatase, non-receptor type 1 (Ptpn1), mRNA. Adherens junction;; Insulin signaling pathway CLASS Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] dephosphorylation;; endoplasmic reticulum;; hydrolase activity;; insulin receptor signaling pathway;; membrane;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle catalytic activity;; molecular transducer activity hydrolase activity;; signal transducer activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell communication;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; response to chemical stimulus;; response to endogenous stimulus 1169.8554 1150.9218 1121.9598 377.9926 306.8713 352.0756 0.0018649826 1.73635 10.16416 8.42782 1328869 1417406_at 7 chr7:28274785-28275298 7 A3 chr7:28271971-28275333 7 A3 RSQ Mm.153684 NM_018820 1 1 55942 Sertad1 SERTA domain containing 1 (Sertad1), mRNA. cytoplasm;; negative regulation of cell growth;; nucleus;; positive regulation of transcription;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription activator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription activator activity biological regulation;; cellular process;; growth;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cell growth;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process 1017.8614 1010.3066 975.0140 455.7398 494.0292 532.3652 0.0021536322 1.02146 9.96706 8.94560 1328922 1417472_at 15 43.3 cM chr15:77591331-77591589 15 E1 chr15:77591018-77672545 15 E1 RSQ Mm.29677 NM_022410 1 1 17886 AL583886.1 Myh9 myosin, heavy polypeptide 9, non-muscle (Myh9), transcript variant 1, mRNA. Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Tight junction actin binding;; actin filament binding;; actin filament-based movement;; actin-dependent ATPase activity;; ADP binding;; ATP binding;; calmodulin binding;; cell adhesion;; cell cortex;; cell morphogenesis involved in differentiation;; cell motion;; cell-cell adherens junction;; cell-cell adhesion;; cortical cytoskeleton;; cytoplasm;; establishment of meiotic spindle localization;; establishment of T cell polarity;; immunological synapse;; immunological synapse;; in utero embryonic development;; meiotic metaphase I;; meiotic spindle organization;; microfilament motor activity;; motor activity;; myoblast fusion;; myosin complex;; neuromuscular junction;; nucleotide binding;; plasma membrane;; plasma membrane;; protein binding;; regulation of cell shape;; spindle;; stress fiber;; stress fiber;; uropod;; uropod;; uropod organization cell;; cell part;; macromolecular complex;; organelle;; organelle part;; synapse cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; neuromuscular junction;; non-membrane-bounded organelle;; organelle part;; protein complex;; trailing edge binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; protein binding anatomical structure formation;; biological adhesion;; biological regulation;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; multicellular organismal process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell activation;; cell adhesion;; cell cycle;; cell cycle process;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; cellular localization;; embryonic development;; establishment of localization;; establishment of localization in cell;; establishment of organelle localization;; establishment or maintenance of cell polarity;; leukocyte activation;; localization of cell;; membrane organization;; microtubule-based process;; multicellular organismal development;; organelle organization;; regulation of biological process;; regulation of biological quality;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; syncytium formation;; transport 124.0008 114.1493 127.4615 46.8627 41.6515 40.4314 8.9879026e-05 1.50495 6.92763 5.42269 1328931 1417483_at 16 chr16:55811560-55812070 16 C1.1 chr16:55811489-55838754 16 C1.1 RSQ NM_001159395 3 1 80859 Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 3, mRNA. inflammatory response;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; response to stress 3179.7873 3159.6374 3214.7762 1206.5789 1184.2030 1255.4512 0.00011318412 1.39012 11.63692 10.24680 1343507 1417500_a_at 2 89.0 cM chr2:157942444-157942708 2 H1 chr2:157942140-157972128 2 H1 RSQ Mm.330731 NM_009373 1 1 21817 RP23-396G1.2 Tgm2 transglutaminase 2, C polypeptide (Tgm2), mRNA. Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 460.5297 463.9381 443.0131 178.4857 213.4886 193.0964 0.0021148495 1.22843 8.83205 7.60362 1328951 1417507_at 11 65.0 cM chr11:105795150-105795596 11 E1 chr11:105795017-105805461 11 E1 RSQ Mm.149403 NM_007805 1 1 13056 RP23-186E14.2 Cyb561 cytochrome b-561 (Cyb561), mRNA. cytoplasmic vesicle;; electron transport chain;; ferric-chelate reductase activity;; integral to membrane;; iron ion binding;; membrane;; metal ion binding;; transport cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; vesicle binding;; catalytic activity ion binding;; oxidoreductase activity cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; oxidation reduction;; transport 790.1379 761.1454 707.5964 394.9297 388.4751 307.5240 0.0056890275 1.05770 9.55492 8.49723 1328952 1417508_at 15 chr15:36169777-36170226 15 B3.1 chr15:36169688-36212902 15 B3.1 RSQ Mm.5181 NM_013923 1 1 30945 Rnf19a ring finger protein 19A (Rnf19a), mRNA. integral to membrane;; ligase activity;; membrane;; metal ion binding;; modification-dependent protein catabolic process;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 314.4891 309.5207 313.0997 102.5551 97.6477 99.7492 3.5002267e-05 1.64374 8.28708 6.64333 1329035 1417602_at 1 C5 chr1:93312699-93313101 1 D UG5 Mm.218141 18627 Per2 Period homolog 2 (Drosophila) (Per2), mRNA Circadian rhythm - mammal CLASS Cellular Processes; Behavior; Circadian rhythm - mammal [PATH:mmu04710] circadian rhythm;; cytoplasm;; negative regulation of specific transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; rhythmic process;; signal transducer activity;; signal transduction;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; rhythmic process biosynthetic process;; cell communication;; cellular metabolic process;; circadian rhythm;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 136.6527 142.6062 132.5847 45.3365 61.4561 64.2081 0.012388073 1.28409 7.10034 5.81626 1329204 1417821_at 17 B1|17 19.0 cM chr17:35134509-35134926 17 B1 UG5 Mm.22506 110956 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942) viral envelope virion;; virion part viral envelope;; virion part 237.5964 232.3563 231.2765 99.3466 112.8484 122.2624 0.0057884995 1.07319 7.86868 6.79549 1329205 1417822_at 17 B1|17 19.0 cM chr17:35133679-35134254 17 B1 UGA Mm.22506 110956 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942) viral envelope virion;; virion part viral envelope;; virion part 246.7763 268.5551 233.2480 120.0337 121.7201 127.7511 0.00080804409 1.01665 7.96062 6.94397 1329298 1417929_at 14 chr14:55341124-55341626 14 C3 chr14:55341051-55400723 14 C3 RSQ Mm.276831 NM_016972 1 1 50934 Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), mRNA. amine transmembrane transporter activity;; amino acid transmembrane transporter activity;; amino acid transport;; cytoplasm;; integral to membrane;; L-amino acid transmembrane transporter activity;; L-amino acid transport;; membrane;; plasma membrane;; transport cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 865.7190 894.0942 1034.7201 211.8966 166.6975 169.8951 0.00013282566 2.35342 9.85902 7.50560 1329299 1417930_at 10 70.0 cM chr10:127098035-127098540 10 D3 chr10:127097973-127103759 10 D3 RSQ Mm.336898 NM_001122895 2 1 17937 Nab2 Ngfi-A binding protein 2 (Nab2), transcript variant 2, mRNA. endochondral ossification;; myelination;; negative regulation of transcription;; nucleus;; regulation of epidermis development;; regulation of transcription;; regulation of transcription, DNA-dependent;; Schwann cell differentiation;; transcription;; transcription regulator activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle transcription regulator activity transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; ensheathment of neurons;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ossification;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; system process 424.5262 392.7871 384.7675 201.4742 199.2366 175.0066 0.00039123421 1.06370 8.64505 7.58135 1343611 1418094_s_at 11 chr11:84778338-84779387 11 C chr11:84771255-84779556 11 C RSQ Mm.1641 NM_007607 1 1 12351 RP23-167D6.1 Car4 carbonic anhydrase 4 (Car4), mRNA. Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] anchored to membrane;; carbonate dehydratase activity;; lyase activity;; membrane;; metal ion binding;; one-carbon metabolic process;; plasma membrane;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 1616.0867 1573.0423 1580.4144 192.9692 173.9628 200.9535 0.00026031051 3.07271 10.63457 7.56186 1329642 1418349_at 18 15.0 cM chr18:36664709-36665151 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 4203.5671 4298.9217 4240.6475 314.8332 306.3186 352.1650 0.00020409707 3.71326 12.05241 8.33915 1329643 1418350_at 18 15.0 cM chr18:36665688-36667226 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 1326.8609 1329.9098 1361.3830 700.4529 722.3739 525.4104 0.018028408 1.05857 10.38726 9.32868 1329711 1418432_at 1 chr1:87746036-87746518 1 C5 chr1:87690021-87748152 1 C5 RSQ Mm.26135 NM_133781 1 1 12283 Cab39 calcium binding protein 39 (Cab39), mRNA. mTOR signaling pathway CLASS Environmental Information Processing; Signal Transduction; mTOR signaling pathway [PATH:mmu04150] calcium ion binding;; cytoplasm cell;; cell part cell part;; intracellular;; intracellular part binding ion binding 1804.0255 1845.1241 1839.5408 435.9297 753.0758 824.2191 0.034586344 1.50005 10.83721 9.33716 1329744 1418469_at 16 C3.1 chr16:76290241-76290637 16 C3.1 UGA Mm.455873 268903 Nrip1 Receptor interacting protein 140 histone deacetylase binding;; histone deacetylase complex;; lipid storage;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; ovarian follicle rupture;; ovulation;; protein binding;; receptor activity;; receptor binding;; regulation of transcription, DNA-dependent;; retinoid X receptor binding;; transcription;; transcription corepressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity protein binding;; signal transducer activity;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; biosynthetic process;; cellular metabolic process;; gamete generation;; macromolecule localization;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 248.9299 268.4852 246.2027 134.6512 73.0052 94.5830 0.030192901 1.38183 7.99067 6.60884 1343687 1418507_s_at 10 C2|10 52.0 cM chr10:94874243-94874582 10 C2 UGA Mm.474283 216233 Socs2 Suppressor of cytokine signaling 2 (Socs2), mRNA Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 391.4507 383.9652 370.3980 191.5080 186.8575 143.5187 0.011359553 1.14610 8.57682 7.43072 1329812 1418561_at 1 28.9 cM chr1:55042033-55042501 1 C1.2 chr1:55042012-55084322 1 C1.2 RSQ Mm.279736 NM_031179 1 1 81898 Sf3b1 splicing factor 3b, subunit 1 (Sf3b1), mRNA. anterior/posterior pattern formation;; binding;; chromatin binding;; mRNA processing;; nuclear mRNA splicing, via spliceosome;; nucleus;; protein binding;; RNA splicing;; RNA splicing factor activity, transesterification mechanism;; spliceosomal complex cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding;; catalytic activity chromatin binding;; protein binding;; RNA splicing factor activity, transesterification mechanism cellular process;; developmental process;; metabolic process;; multicellular organismal process cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process 4364.5741 4422.7925 4415.6374 1240.1825 1600.6565 1290.1840 0.0044841721 1.68554 12.10359 10.41805 1329818 1418571_at 17 chr17:23812771-23812982 17 A3.3 chr17:23812411-23814416 17 A3.3 RSQ NM_001161746 2 1 27279 Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), transcript variant 2, mRNA. Cytokine-cytokine receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] angiogenesis;; apoptosis;; cell adhesion;; cell death;; cell differentiation;; cell surface;; integral to membrane;; membrane;; multicellular organismal development;; plasma membrane;; positive regulation of axon extension;; protein binding;; receptor activity;; ruffle;; substrate-bound cell migration, cell attachment to substrate cell;; cell part cell leading edge;; cell part;; cell projection;; cell surface;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; localization;; locomotion;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell death;; cell motility;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; localization of cell;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular component organization;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 3940.8133 4157.4390 4121.4174 1005.5524 1363.7326 1130.8393 0.0038825844 1.81480 11.99156 10.17677 1343706 1418572_x_at 17 chr17:23812771-23812982 17 A3.3 chr17:23812411-23814416 17 A3.3 RSQ NM_001161746 2 1 27279 Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), transcript variant 2, mRNA. Cytokine-cytokine receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] angiogenesis;; apoptosis;; cell adhesion;; cell death;; cell differentiation;; cell surface;; integral to membrane;; membrane;; multicellular organismal development;; plasma membrane;; positive regulation of axon extension;; protein binding;; receptor activity;; ruffle;; substrate-bound cell migration, cell attachment to substrate cell;; cell part cell leading edge;; cell part;; cell projection;; cell surface;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; localization;; locomotion;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell death;; cell motility;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; localization of cell;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular component organization;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 551.4382 590.7990 561.2075 204.8350 209.3547 194.5793 4.3928093e-06 1.48454 9.14866 7.66411 1329909 1418674_at 15 4.6 cM chr15:6763697-6764043 15 A1 chr15:6763576-6824313 15 A1 RSQ Mm.10760 NM_011019 1 1 18414 Osmr oncostatin M receptor (Osmr), mRNA. Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] cell surface receptor linked signal transduction;; cytokine receptor activity;; integral to membrane;; integral to plasma membrane;; membrane;; oncostatin-M receptor activity;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 1271.6748 1202.1519 1217.2630 345.4227 341.6724 237.5361 0.0068075784 2.01755 10.26445 8.24690 1330049 1418835_at 10 chr10:110945144-110945563 10 D1 chr10:110943341-110945705 10 D1 RSQ Mm.3117 NM_009344 1 1 21664 Phlda1 pleckstrin homology-like domain, family A, member 1 (Phlda1), mRNA. apoptosis;; cytoplasm;; cytoplasmic vesicle;; FasL biosynthetic process;; membrane;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle;; vesicle cellular process;; death;; metabolic process biosynthetic process;; cell death;; cellular metabolic process;; macromolecule metabolic process 5100.3858 5050.0920 5082.7644 2796.1651 2683.5834 2146.5024 0.013467617 1.00764 12.30996 11.30232 1330097 1418901_at 2 95.5 cM chr2:167515579-167515878 2 H3 chr2:167514414-167515918 2 H3 RSQ Mm.439656 NM_009883 1 1 12608 RP24-151H6.1 Cebpb CCAAT/enhancer binding protein (C/EBP), beta (Cebpb), mRNA. IL 6 signaling pathway anti-apoptosis;; cytoplasm;; DNA binding;; embryonic placenta development;; fat cell differentiation;; induction of apoptosis;; mammary gland epithelial cell differentiation;; mammary gland epithelial cell proliferation;; neuron differentiation;; nucleus;; positive regulation of transcription;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; protein dimerization activity;; protein heterodimerization activity;; protein homodimerization activity;; regulation of interleukin-6 biosynthetic process;; regulation of transcription, DNA-dependent;; RNA polymerase II transcription factor activity, enhancer binding;; sequence-specific DNA binding;; transcription;; transcription activator activity;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process 1466.3991 1503.8276 1546.8469 658.2704 845.0681 552.6684 0.021407176 1.15729 10.55587 9.39858 1330123 1418932_at 13 32.0 cM chr13:53062781-53063171 13 B1 chr13:53062577-53076408 13 B1 RSQ Mm.136604 NM_017373 2 2 18030 Nfil3 nuclear factor, interleukin 3, regulated (Nfil3), mRNA. DNA binding;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; rhythmic process;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; rhythmic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 457.4114 434.6008 431.5846 174.8988 260.6096 214.0515 0.022067362 1.04549 8.78480 7.73931 1330208 1419034_at 2 chr2:152104805-152104961 2 G3 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 2 2 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 262.5408 240.0964 218.9852 98.9287 82.4758 114.1714 0.0030702464 1.29643 7.90619 6.60976 1330303 1419149_at 5 chr5:137537541-137537908 5 G2 chr5:137537373-137548142 5 G2 RSQ Mm.250422 NM_008871 1 1 18787 Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1), mRNA. Fibrinolysis Pathway;; Platelet Amyloid Precursor Protein Pathway Complement and coagulation cascades CLASS Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Cellular Processes; Immune System; Complement and coagulation cascades [PATH:mmu04610];; p53 signaling pathway endopeptidase inhibitor activity;; extracellular region;; protein binding;; regulation of angiogenesis;; regulation of cell proliferation;; serine-type endopeptidase activity;; serine-type endopeptidase inhibitor activity extracellular region binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; hydrolase activity;; protein binding anatomical structure formation;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; multicellular organismal development;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 520.0314 523.7359 517.9739 232.8869 241.2085 271.0628 0.003661152 1.07059 9.02396 7.95337 1330344 1419203_at 11 chr11:60734486-60734979 11 B2 chr11:60734442-60745369 11 B2 RSQ NR_027800 1 1 24082 Gtlf3a gene trap locus F3a (Gtlf3a), non-coding RNA. 117.4738 134.3279 122.2501 58.7293 59.4489 58.7069 0.0025817066 1.07815 6.95983 5.88168 1330348 1419208_at 18 0.0 cM chr18:4331546-4331913 18 A1 chr18:4331324-4352951 18 A1 RSQ Mm.3275 NM_007746 1 1 26410 Map3k8 mitogen-activated protein kinase kinase kinase 8 (Map3k8), mRNA. MAPKinase Signaling Pathway MAPK signaling pathway;; T cell receptor signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660];; Toll-like receptor signaling pathway ATP binding;; cell cycle;; cytoplasm;; kinase activity;; magnesium ion binding;; MAP kinase kinase kinase activity;; metal ion binding;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; signal transduction;; transferase activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity;; molecular transducer activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cell cycle;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 48.8764 55.4908 63.7484 21.5839 20.7693 22.9311 0.0028945968 1.35735 5.79985 4.44250 1330349 1419209_at 5 51.0 cM chr5:91321568-91321979 5 E1 chr5:91320270-91322147 5 E1 RSQ Mm.21013 NM_008176 1 1 14825 Cxcl1 chemokine (C-X-C motif) ligand 1 (Cxcl1), mRNA. Chemokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062];; Cytokine-cytokine receptor interaction chemokine activity;; cytokine activity;; extracellular region;; extracellular space;; growth factor activity;; immune response;; inflammatory response extracellular region;; extracellular region part extracellular region part;; extracellular space binding protein binding immune system process;; response to stimulus immune response;; response to external stimulus;; response to stress 7353.9914 7360.2075 7427.3301 1067.1625 1922.5705 1670.4169 0.012238767 2.29136 12.84949 10.55813 1330359 1419220_at 9 F4 chr9:119923004-119923392 9 F4 UGA Mm.10117 22437 Xirp1 Xin actin binding;; actin cytoskeleton organization;; cardiac muscle cell development;; cell junction;; cell-cell adherens junction;; fascia adherens;; filamin-C binding;; heart morphogenesis;; intercalated disc;; negative regulation of cell proliferation;; protein binding;; regulation of membrane potential;; sarcomere organization cell;; cell part cell part;; membrane;; membrane part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular homeostasis;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of biological quality;; regulation of cellular process 556.0256 580.7698 583.7638 238.1519 247.4853 351.9975 0.025894344 1.06124 9.16336 8.10212 1330384 1419255_at 11 13.0 cM chr11:30007644-30008198 11 A3.3 chr11:30006842-30098257 11 A3.3 RSQ Mm.123110 NM_009260 1 1 20742 RP23-189P1.1 Spnb2 spectrin beta 2 (Spnb2), transcript variant 2, mRNA. Tight junction CLASS Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] actin binding;; actin filament capping;; calmodulin binding;; common-partner SMAD protein phosphorylation;; cortical cytoskeleton;; cytoplasm;; cytoskeleton;; membrane;; nucleus;; plasma membrane;; protein binding;; SMAD protein nuclear translocation;; spectrin;; structural constituent of cytoskeleton cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; structural molecule activity protein binding;; structural constituent of cytoskeleton anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cellular component assembly;; cellular component disassembly;; cellular localization;; cellular macromolecular complex subunit organization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecular complex subunit organization;; macromolecule localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of cellular component biogenesis;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; transport 1425.9557 1448.8141 1350.6612 440.3720 655.3326 685.5480 0.022428861 1.27268 10.45927 9.18659 1330421 1419301_at 7 44.5 cM chr7:96557344-96557739 7 E1 chr7:96552875-96558620 7 E1 RSQ Mm.86755 NM_008055 1 1 14366 Fzd4 frizzled homolog 4 (Drosophila) (Fzd4), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Endocrine System; Melanogenesis [PATH:mmu04916] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210] Human Diseases; Cancers; Basal cell carcinom;; Colorectal cancer;; Melanogenesis;; Pathways in cancer;; Wnt signaling pathway cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; protein binding;; receptor activity;; signal transducer activity;; signal transduction;; transmembrane receptor activity;; Wnt receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 853.5776 866.5564 826.1962 284.0782 330.2943 363.1650 0.0042311131 1.38821 9.72896 8.34074 1330481 1419376_at 2 chr2:110201583-110202080 2 E3 chr2:110201081-110203150 2 E3 RSQ Mm.291809 NM_026271 1 1 67606 RP23-110I8.1 Fibin fin bud initiation factor homolog (zebrafish) (Fibin), mRNA. extracellular region;; Golgi apparatus cell;; cell part;; extracellular region;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 296.1956 264.9176 258.2057 61.7332 50.4948 41.1376 0.0020670409 2.43459 8.09073 5.65614 1343853 1419394_s_at 3 43.6 cM chr3:90473446-90473926 3 F1 chr3:90472992-90473956 3 F1 RSQ Mm.21567 NM_013650 1 1 20201 S100a8 S100 calcium binding protein A8 (calgranulin A) (S100a8), mRNA. calcium ion binding;; chemotaxis binding ion binding locomotion;; response to stimulus behavior;; response to chemical stimulus;; response to external stimulus;; taxis 324.7642 284.0103 305.6715 122.6283 144.5561 145.9770 0.00060598368 1.14855 8.24963 7.10108 1330502 1419405_at 7 chr7:88047145-88049749 7 D3 chr7:88047121-88049922 7 D3 RSQ Mm.22246 NM_026523 1 1 68039 Nmb neuromedin B (Nmb), mRNA. extracellular region;; neuropeptide signaling pathway extracellular region biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 239.2075 268.7490 250.1674 117.1287 114.0538 108.5997 0.00011401705 1.15686 7.97966 6.82280 1330567 1419488_at 5 chr5:34839136-34839321 5 B2 chr5:34838744-34856628 5 B2 RSQ Mm.28615 NM_139064 1 1 231130 Tnip2 TNFAIP3 interacting protein 2 (Tnip2), mRNA. cytoplasm;; I-kappaB kinase/NF-kappaB cascade;; protein binding cell;; cell part cell part;; intracellular;; intracellular part binding protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 860.3207 807.8935 832.0106 450.4418 319.0856 369.4181 0.013183251 1.14837 9.70240 8.55404 1343904 1419647_a_at 17 chr17:35959305-35959827 17 B1 chr17:35958657-35959856 17 B1 RSQ Mm.25613 NM_133662 1 1 15937 Ier3 immediate early response 3 (Ier3), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 214.5170 225.2440 192.5408 79.0585 64.8317 79.5374 0.00042654615 1.50409 7.71644 6.21235 1343918 1419700_a_at 5 chr5:44384916-44385436 5 B3 chr5:44384860-44492920 5 B3 RSQ Mm.6250 NM_008935 1 1 19126 Prom1 prominin 1 (Prom1), mRNA. apical plasma membrane;; brush border;; cell projection;; cell surface;; extracellular space;; integral to membrane;; integral to plasma membrane;; membrane;; microvillus;; plasma membrane;; stereocilium cell;; cell part;; extracellular region;; extracellular region part;; organelle;; organelle part apical part of cell;; cell part;; cell projection;; cell surface;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle;; organelle part;; stereocilium 656.2367 613.0088 603.6055 273.7075 281.2495 328.5653 0.0017396608 1.08769 9.28510 8.19741 1343936 1419816_s_at 4 chr4:150241573-150241791 4 E2 chr4:150229199-150242989 4 E2 RSQ Mm.318841 NM_133753 1 1 74155 RP23-272N19.4 Errfi1 ERBB receptor feedback inhibitor 1 (Errfi1), mRNA. cytoplasm;; cytosol;; protein binding;; receptor activity;; stress-activated protein kinase signaling pathway cell;; cell part cell part;; intracellular;; intracellular part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular response to stimulus;; regulation of biological process;; regulation of cellular process;; response to stress 857.6481 875.9306 893.0172 368.9323 424.3230 309.3892 0.0097962752 1.26398 9.77382 8.50984 1343955 1419874_x_at 9 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 808.2145 838.3654 811.4856 291.5900 302.8741 305.0928 9.6337626e-07 1.45033 9.67815 8.22783 1343970 1419927_s_at 1 chr1:136403861-136404136 1 E4 chr1:136391236-136404462 1 E4 RSQ Mm.198119 NM_145510 1 1 98710 Rabif RAB interacting factor (Rabif), mRNA. guanyl-nucleotide exchange factor activity;; metal ion binding;; protein transport;; small GTPase mediated signal transduction;; transport;; zinc ion binding binding;; enzyme regulator activity ion binding;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; establishment of localization;; localization;; regulation of biological process cell communication;; establishment of localization;; establishment of protein localization;; macromolecule localization;; regulation of biological process;; regulation of cellular process;; transport 751.6519 678.1258 612.2388 158.8062 92.2823 91.5046 0.0057342101 2.62080 9.40576 6.78496 1331270 1420558_at 1 86.6 cM chr1:166079630-166080083 1 H2.2 chr1:166053831-166079876 1 H2.2 RSQ Mm.3337 NM_011347 1 1 20344 Selp selectin, platelet (Selp), mRNA. Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 413.1140 357.2566 339.3122 145.5516 161.9720 175.9615 0.00051237062 1.19786 8.52589 7.32803 1331285 1420575_at 8 45.0 cM chr8:96676690-96677865 8 C5 chr8:96676643-96678031 8 C5 RSQ Mm.2064 NM_013603 1 1 17751 Mt3 metallothionein 3 (Mt3), mRNA. cellular metal ion homeostasis;; copper ion binding;; metal ion binding;; negative regulation of neurogenesis;; synaptic vesicle;; zinc ion binding cell;; cell part;; organelle;; synapse;; synapse part cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; synapse part;; synaptic vesicle;; vesicle binding ion binding biological regulation;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; cellular developmental process;; cellular homeostasis;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 86.4955 85.0225 89.6762 40.2297 45.4187 43.7427 0.00063447931 1.01487 6.44366 5.42879 1331346 1420667_at 11 chr11:75582506-75583066 11 B5 chr11:75582591-75609559 11 B5 RSQ Mm.5137 NM_007873 1 1 13447 RP23-78H4.2 Doc2b double C2, beta (Doc2b), mRNA. calcium ion binding;; calcium-dependent phospholipid binding;; membrane;; synaptic vesicle;; transport;; transporter activity cell;; cell part;; organelle;; synapse;; synapse part cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle;; synapse part;; synaptic vesicle;; vesicle binding;; transporter activity ion binding;; lipid binding establishment of localization;; localization establishment of localization;; transport 695.1276 690.1875 692.9852 289.5110 253.5276 313.0794 0.0047084115 1.28493 9.43622 8.15129 1331467 1420836_at 14 D2 chr14:76161375-76161441 14 D3 UGA Mm.46067 67554 Slc25a30 Solute carrier family 25, member 30, mRNA (cDNA clone MGC:31367 IMAGE:4238839) binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport;; transporter activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; transporter activity establishment of localization;; localization establishment of localization;; transport 1973.5586 1927.1863 1967.2630 284.3779 173.0591 137.4432 0.0082673731 3.37045 10.93361 7.56316 1331591 1420991_at 19 chr19:36187159-36191361 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1537.9415 1602.5127 1537.0619 182.5408 134.9352 92.3970 0.0060880467 3.56696 10.60629 7.03932 1331592 1420992_at 19 chr19:36186663-36186994 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 727.8373 741.9241 745.0505 259.5930 295.1997 251.7090 0.0019270313 1.46084 9.52793 8.06709 1344415 1421679_a_at 17 15.23 cM chr17:29235417-29235782 17 A3.3 chr17:29230716-29237667 17 A3.3 RSQ Mm.477981 NM_007669 2 1 12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA. ATM Signaling Pathway;; Cell Cycle: G1/S Check Point;; Cell Cycle: G2/M Checkpoint;; Cyclins and Cell Cycle Regulation;; Effects of calcineurin in Keratinocyte Differentiation;; Erythropoietin mediated neuroprotection through NF-kB;; Influence of Ras and Rho proteins on G1 to S Transition;; p53 Signaling Pathway Bladder cancer;; Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases;;; ErbB signaling pathway;; Glioma;; Melanoma;; p53 signaling pathway;; Pathways in cancer;; Prostate cancer cell cycle;; cell cycle arrest;; cyclin binding;; cyclin-dependent protein kinase holoenzyme complex;; cyclin-dependent protein kinase inhibitor activity;; cytoplasm;; cytosol;; kinase activity;; metal ion binding;; negative regulation of apoptosis;; negative regulation of cell proliferation;; negative regulation of cyclin-dependent protein kinase activity;; nucleus;; positive regulation of B cell proliferation;; positive regulation of programmed cell death;; protein binding;; protein kinase inhibitor activity;; regulation of cell cycle;; response to DNA damage stimulus;; response to UV;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; kinase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell cycle;; cell cycle process;; cell death;; cell proliferation;; cellular metabolic process;; leukocyte activation;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 229.8900 222.1572 247.8473 114.2189 137.5723 91.0081 0.020052214 1.04864 7.86451 6.81588 1332171 1421811_at 2 F1-F3|2 65.0 cM chr2:117952274-117952837 2 E5 UGA Mm.4159 21825 RP23-234E8.1 Thbs1 Thrombospondin 1 (Thbs1), mRNA TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Bladder cancer CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] Human Diseases; Cancers; Bladder cancer [PATH;; ECM-receptor interaction;; Focal adhesion;; p53 signaling pathway;; TGF-beta signaling pathway calcium ion binding;; cell adhesion;; extracellular matrix binding;; extracellular region;; extracellular space;; heparin binding;; inflammatory response;; negative regulation of angiogenesis;; positive regulation of cell-substrate adhesion;; protein binding;; structural molecule activity extracellular region;; extracellular region part extracellular region part;; extracellular space binding;; structural molecule activity carbohydrate binding;; extracellular matrix binding;; ion binding;; pattern binding;; protein binding anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; multicellular organismal development;; negative regulation of biological process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; response to external stimulus;; response to stress 397.1650 417.6318 424.7516 161.7004 188.9437 150.3393 0.0030560901 1.31303 8.69005 7.37702 1332178 1421821_at 9 5.0 cM chr9:21553593-21554081 9 A3 chr9:21528037-21554363 9 A3 RSQ Mm.3213 NM_010700 1 1 16835 Ldlr low density lipoprotein receptor (Ldlr), mRNA. FXR and LXR Regulation of Cholesterol Metabolism;; SREBP control of lipid synthesis Endocytosis CLASS Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] calcium ion binding;; cholesterol homeostasis;; cholesterol homeostasis;; cholesterol metabolic process;; cholesterol transport;; coated pit;; endocytosis;; endosome;; integral to membrane;; lipid metabolic process;; lipid transport;; lipoprotein catabolic process;; lipoprotein catabolic process;; lipoprotein metabolic process;; low-density lipoprotein binding;; low-density lipoprotein particle;; low-density lipoprotein receptor activity;; low-density lipoprotein receptor activity;; membrane;; protein binding;; receptor activity;; steroid metabolic process;; transport;; very-low-density lipoprotein receptor activity cell;; cell part;; extracellular region;; extracellular region part;; macromolecular complex;; organelle cell part;; endomembrane system;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; plasma lipoprotein particle;; protein-lipid complex binding;; molecular transducer activity ion binding;; protein binding;; signal transducer activity biological regulation;; cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process alcohol metabolic process;; biosynthetic process;; catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; membrane organization;; primary metabolic process;; regulation of biological quality;; transport;; vesicle-mediated transport 677.5097 682.5045 642.6164 226.6614 325.1630 325.2075 0.01795718 1.21066 9.38220 8.17154 1344488 1421957_a_at 16 22.85 cM chr16:32471767-32471880 16 B3 chr16:32451788-32472101 16 B3 RSQ Mm.390903 NM_009981 1 1 13026 Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform (Pcyt1a), mRNA. Aminophosphonate metabolism;; Glycerophospholipid metabolism;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] Metabolism; Metabolism of Other Amino Acids; Aminophosphonate metabolism [PATH:mmu00440] biosynthetic process;; catalytic activity;; choline-phosphate cytidylyltransferase activity;; cytoplasm;; endoplasmic reticulum membrane;; glycogen granule;; membrane;; nucleotidyltransferase activity;; phosphatidylcholine biosynthetic process;; phosphatidylcholine biosynthetic process;; phospholipid biosynthetic process;; response to abiotic stimulus;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process;; response to stimulus alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; organophosphate metabolic process;; primary metabolic process;; response to abiotic stimulus 63.4071 57.6838 47.4780 22.3499 25.1900 34.8383 0.014398681 1.04876 5.80195 4.75319 1332410 1422134_at 7 5.0 cM chr7:19888336-19888846 7 A3 chr7:19888044-19895394 7 A3 RSQ Mm.248335 NM_008036 1 1 14282 Fosb FBJ osteosarcoma oncogene B (Fosb), mRNA. FOSB gene expression and drug abuse DNA binding;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 2866.2196 2773.5150 2814.3290 1116.0755 1341.0477 1036.5357 0.0066597163 1.28336 11.46034 10.17697 1332654 1422473_at 4 C6|4 46.8 cM chr4:102277892-102278309 4 C6 UG5 Mm.20181 18578 RP23-57D24.1 Pde4b Phosphodiesterase 4B, cAMP specific, mRNA (cDNA clone IMAGE:5354427) Purine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] 3',5'-cyclic-AMP phosphodiesterase activity;; smooth muscle contraction catalytic activity hydrolase activity multicellular organismal process system process 17311.5408 17626.1305 17479.4058 1763.3971 2121.9924 1128.1347 0.006116709 3.43439 14.09275 10.65836 1344655 1422557_s_at 8 45.0 cM chr8:96703191-96704176 8 C5 chr8:96702988-96704227 8 C5 RSQ Mm.192991 NM_013602 1 1 17748 Mt1 metallothionein 1 (Mt1), mRNA. cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 2728.9297 2861.6266 2879.3005 73.1061 89.8435 88.0124 0.00015515705 5.08245 11.46275 6.38030 1332723 1422562_at 8 D3 chr8:107152017-107152528 8 D3 UG5 Mm.29467 56437 Rrad Ras-related associated with diabetes (Rrad), mRNA calmodulin binding;; GTP binding;; nucleotide binding;; small GTPase mediated signal transduction binding nucleotide binding;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 612.2141 626.3741 602.7570 298.5463 305.0408 290.0063 4.984057e-06 1.04320 9.26140 8.21820 1332733 1422573_at 7 52.0 cM chr7:117955390-117955823 7 F1 chr7:117916117-117955909 7 F1 RSQ Mm.3238 NM_009667 1 1 11717 Ampd3 adenosine monophosphate deaminase 3 (Ampd3), mRNA. Metabolic pathways CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230];; Purine metabolism AMP deaminase activity;; deaminase activity;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;; nucleotide metabolic process;; purine base metabolic process;; purine ribonucleoside monophosphate biosynthetic process catalytic activity deaminase activity;; hydrolase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process 688.1540 727.5920 763.3859 261.3204 258.8752 314.1194 0.0010443655 1.38963 9.50328 8.11365 1332904 1422788_at 2 chr2:84798112-84798561 2 D chr2:84776812-84798666 2 D RSQ Mm.290729 NM_021398 1 1 58207 RP23-232L15.1 Slc43a3 solute carrier family 43, member 3 (Slc43a3), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 254.4957 249.7773 262.9522 45.4336 38.7496 33.1057 0.0018638421 2.72128 7.99822 5.27693 1332965 1422864_at 16 62.2 cM chr16:92603923-92604494 16 C4 chr16:92601710-92826311 16 C4 RSQ Mm.4081 NM_001111022 4 1 12394 Runx1 runt related transcription factor 1 (Runx1), transcript variant 2, mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mmu05220];; Chronic myeloid leukemia;; Pathways in cancer ATP binding;; behavioral response to pain;; central nervous system development;; definitive hemopoiesis;; DNA binding;; embryonic hemopoiesis;; in utero embryonic development;; liver development;; neuron development;; neuron differentiation;; nucleus;; positive regulation of angiogenesis;; protein binding;; regulation of transcription, DNA-dependent;; response to retinoic acid;; skeletal system development;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; multicellular organismal response to stress;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress 72.8341 113.7913 99.7284 32.7863 33.6534 31.1564 0.01327002 1.52919 6.55224 5.02305 1332966 1422865_at 16 62.2 cM chr16:92601710-92826311 16 C4 RSQ Mm.4081 NM_001111022 4 1 12394 Runx1 runt related transcription factor 1 (Runx1), transcript variant 2, mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mmu05220];; Chronic myeloid leukemia;; Pathways in cancer ATP binding;; behavioral response to pain;; central nervous system development;; definitive hemopoiesis;; DNA binding;; embryonic hemopoiesis;; in utero embryonic development;; liver development;; neuron development;; neuron differentiation;; nucleus;; positive regulation of angiogenesis;; protein binding;; regulation of transcription, DNA-dependent;; response to retinoic acid;; skeletal system development;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; multicellular organismal response to stress;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress 565.6472 531.9279 577.7242 217.0964 252.9191 294.0813 0.008085639 1.14276 9.12436 7.98160 1332998 1422904_at 1 chr1:164806985-164807074 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 324.3741 402.0277 419.1408 105.3137 111.7462 152.5590 0.0020098326 1.64270 8.56799 6.92528 1344723 1422905_s_at 1 chr1:164806589-164806972 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 592.1016 571.8880 623.0288 289.8741 274.8186 325.9617 0.0012826571 1.00742 9.21748 8.21006 1333004 1422912_at 14 15.0 cM chr14:47003403-47003996 14 C1 chr14:47003194-47010274 14 C1 RSQ Mm.6813 NM_007554 1 1 12159 RP23-87H19.2 Bmp4 bone morphogenetic protein 4 (Bmp4), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Hedgehog signaling pathway [PATH:mmu04340] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Hedgehog signaling pathway;; Pathways in cancer;; TGF-beta signaling pathway anatomical structure formation involved in morphogenesis;; angiogenesis;; BMP signaling pathway;; BMP signaling pathway;; branching involved in lung morphogenesis;; branching involved in prostate gland morphogenesis;; branching involved in ureteric bud morphogenesis;; bronchus development;; bud dilation involved in lung branching;; camera-type eye development;; cartilage development;; cell differentiation;; cell fate commitment;; cytokine activity;; dorsal/ventral neural tube patterning;; embryonic morphogenesis;; epithelial cell proliferation involved in lung morphogenesis;; erythrocyte differentiation;; extracellular region;; extracellular space;; forebrain development;; germ cell development;; growth;; growth factor activity;; heart development;; heparin binding;; induction of an organ;; lens induction in camera-type eye;; lung alveolus development;; lung development;; lung morphogenesis;; mammary gland formation;; mesodermal cell fate determination;; metanephros development;; metanephros development;; multicellular organismal development;; negative regulation of cell proliferation;; negative regulation of chondrocyte differentiation;; negative regulation of epithelial cell proliferation;; negative regulation of gene expression;; negative regulation of myoblast differentiation;; negative regulation of prostatic bud formation;; negative regulation of prostatic bud formation;; negative regulation of striated muscle development;; neuron fate commitment;; neuron fate commitment;; odontogenesis of dentine-containing tooth;; odontogenesis of dentine-containing tooth;; ossification;; osteoblast differentiation;; pituitary gland development;; positive regulation of bone mineralization;; positive regulation of cell death;; positive regulation of cell differentiation;; positive regulation of gene expression;; positive regulation of ossification;; positive regulation of osteoblast differentiation;; positive regulation of protein amino acid phosphorylation;; positive regulation of transcription from RNA polymerase II promoter;; post-embryonic development;; prostate gland morphogenesis;; protein binding;; proteinaceous extracellular matrix;; regulation of branching involved in prostate gland morphogenesis;; regulation of cell differentiation;; regulation of gene expression;; regulation of gene expression;; regulation of morphogenesis of a branching structure;; regulation of smooth muscle cell proliferation;; skeletal system development;; skeletal system development;; smooth muscle cell differentiation;; specification of organ position;; telencephalon regionalization;; tissue development;; trachea development;; ureteric bud development;; ureteric bud development;; ureteric bud development extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space binding carbohydrate binding;; pattern binding;; protein binding anatomical structure formation;; biological regulation;; cellular process;; death;; developmental process;; growth;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; developmental growth;; embryonic development;; gamete generation;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ossification;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; post-embryonic development;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; sexual reproduction;; tissue remodeling 3851.2575 3763.3230 3917.4368 833.1458 935.9843 662.7492 0.0037820971 2.25984 11.90820 9.64836 1333245 1423233_at 16 A2|16 9.0 cM chr16:15888053-15888517 16 A2 UGA Mm.347407 12609 Cebpd CCAAT/enhancer binding protein (C/EBP), delta (Cebpd), mRNA DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; promoter binding;; protein binding;; protein dimerization activity;; protein heterodimerization activity;; protein homodimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; specific RNA polymerase II transcription factor activity;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1038.9927 993.4050 1090.4613 256.3508 270.4106 278.2632 3.4088549e-06 1.95555 10.02264 8.06710 1344806 1423250_a_at 1 101.5 cM chr1:188449250-188454584 1 H5 chr1:188447064-188529871 1 H5 RSQ Mm.18213 NM_009367 1 1 21808 Tgfb2 transforming growth factor, beta 2 (Tgfb2), mRNA. Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Cytokine-cytokine receptor interaction;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; Renal cell carcinoma;; TGF-beta signaling pathway activation-induced cell death of T cells;; axon;; axon guidance;; blood vessel development;; blood vessel remodeling;; cartilage condensation;; cell growth;; cell proliferation;; cell soma;; dopamine biosynthetic process;; extracellular matrix organization;; extracellular region;; extracellular space;; growth;; growth factor activity;; hair follicle development;; hair follicle morphogenesis;; heart development;; hemopoiesis;; induction of apoptosis;; negative regulation of keratinocyte differentiation;; neuron development;; neuron fate commitment;; pathway-restricted SMAD protein phosphorylation;; positive regulation of cell cycle;; protein binding;; regulation of apoptosis;; skeletal system development;; somatic stem cell division;; transforming growth factor beta receptor binding cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell soma;; extracellular region part;; extracellular space binding protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell division;; cell growth;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; extracellular structure organization;; immune system development;; leukocyte homeostasis;; localization of cell;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; tissue remodeling 253.6104 251.8186 236.8186 129.8823 109.4371 106.9456 0.0029925649 1.10487 7.95012 6.84525 1344810 1423267_s_at 15 57.4 cM chr15:103174941-103175288 15 F3 chr15:103174716-103197179 15 F3 RSQ NM_010577 1 1 16402 Itga5 integrin alpha 5 (fibronectin receptor alpha) (Itga5), mRNA. ECM-receptor interaction;; Focal adhesion;; Hematopoietic cell lineage;; Regulation of actin cytoskeleton CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] Cellular Processes; Immune System; Hematopoie calcium ion binding;; cell adhesion;; cell-cell adhesion mediated by integrin;; cell-substrate junction assembly;; external side of plasma membrane;; heterophilic cell adhesion;; integral to membrane;; integrin binding;; integrin complex;; integrin-mediated signaling pathway;; leukocyte adhesion;; membrane;; memory;; protein binding;; receptor activity;; synaptosome cell;; cell part;; macromolecular complex cell fraction;; cell part;; cell surface;; membrane;; membrane part;; protein complex binding;; molecular transducer activity ion binding;; protein binding;; signal transducer activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; multicellular organismal process;; regulation of biological process;; response to stimulus behavior;; cell adhesion;; cell communication;; cell junction organization;; cellular component assembly;; regulation of biological process;; regulation of cellular process;; system process 812.3741 814.3961 811.5941 292.5665 475.0839 317.5379 0.030864828 1.20159 9.66673 8.46515 1333391 1423405_at 6 E3|6 46.0 cM chr6:115195833-115196123 6 E3 UG5 Mm.255607 110595 Timp4 Tissue inhibitor of metalloproteinase 4 (Timp4), mRNA Inhibition of Matrix Metalloproteinases enzyme inhibitor activity;; extracellular region;; metalloendopeptidase inhibitor activity;; proteinaceous extracellular matrix extracellular region;; extracellular region part extracellular matrix;; extracellular region part enzyme regulator activity enzyme inhibitor activity;; metalloenzyme regulator activity 615.3186 638.4938 622.9057 206.7074 307.3741 320.0681 0.026542653 1.19635 9.28886 8.09251 1333550 1423597_at 5 chr5:68013016-68013563 5 C3.1 chr5:68009378-68238670 5 C3.1 RSQ Mm.153230 NM_009727 2 1 11980 Atp8a1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (Atp8a1), transcript variant 2, mRNA. ATP binding;; ATP biosynthetic process;; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;; catalytic activity;; cytoplasmic vesicle;; hydrolase activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; integral to membrane;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; nucleotide binding;; phospholipid transport;; phospholipid-translocating ATPase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; vesicle binding;; catalytic activity;; transporter activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; nitrogen compound metabolic process;; primary metabolic process;; transport 548.5184 561.3741 523.8246 200.3573 294.5273 292.9585 0.025677808 1.07397 9.08838 8.01441 1334316 1424598_at 9 26.0 cM chr9:44444736-44445137 9 A5.2 chr9:44412974-44448814 9 A5.2 RSQ Mm.267061 NM_007841 3 1 13209 Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), transcript variant 3, mRNA. ATP binding;; ATP-dependent helicase activity;; cytoplasm;; helicase activity;; hydrolase activity;; nucleic acid binding;; nucleotide binding;; RNA binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity hydrolase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding 2310.2908 2363.1779 2260.7630 864.6558 971.7345 767.6399 0.003715644 1.41943 11.17432 9.75490 1345101 1424607_a_at 3 chr3:42306621-42308720 3 B RSQ XR_030788 15 15 100039204 LOC100039204 PREDICTED: hypothetical protein LOC100039204 (LOC100039204), misc RNA. 2286.4086 2333.3775 2335.1831 961.7436 901.1189 802.9615 0.0026140747 1.38737 11.17880 9.79142 1345103 1424609_a_at IPA Mus musculus, Similar to RIKEN cDNA 1700066C05 gene, clone MGC:28125 IMAGE:3980327, mRNA, complete cds 1882.1954 1981.8484 1861.9929 553.2019 655.3545 381.7645 0.013621537 1.88304 10.89782 9.01478 1334343 1424638_at 17 15.23 cM chr17:29237151-29237610 17 A3.3 chr17:29230716-29237667 17 A3.3 RSQ Mm.477981 NM_007669 2 1 12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA. ATM Signaling Pathway;; Cell Cycle: G1/S Check Point;; Cell Cycle: G2/M Checkpoint;; Cyclins and Cell Cycle Regulation;; Effects of calcineurin in Keratinocyte Differentiation;; Erythropoietin mediated neuroprotection through NF-kB;; Influence of Ras and Rho proteins on G1 to S Transition;; p53 Signaling Pathway Bladder cancer;; Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases;;; ErbB signaling pathway;; Glioma;; Melanoma;; p53 signaling pathway;; Pathways in cancer;; Prostate cancer cell cycle;; cell cycle arrest;; cyclin binding;; cyclin-dependent protein kinase holoenzyme complex;; cyclin-dependent protein kinase inhibitor activity;; cytoplasm;; cytosol;; kinase activity;; metal ion binding;; negative regulation of apoptosis;; negative regulation of cell proliferation;; negative regulation of cyclin-dependent protein kinase activity;; nucleus;; positive regulation of B cell proliferation;; positive regulation of programmed cell death;; protein binding;; protein kinase inhibitor activity;; regulation of cell cycle;; response to DNA damage stimulus;; response to UV;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; kinase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell cycle;; cell cycle process;; cell death;; cell proliferation;; cellular metabolic process;; leukocyte activation;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 340.0717 296.7081 309.6962 152.7802 124.2201 149.2396 0.0011867783 1.15458 8.29910 7.14452 1345189 1424942_a_at 15 32.0 cM chr15:61821207-61821618 15 D1 chr15:61816895-61821916 15 D1 RSQ Mm.2444 NM_010849 1 1 17869 Myc myelocytomatosis oncogene (Myc), mRNA. Cadmium induces DNA synthesis and proliferation in macrophages;; CTCF: First Multivalent Nuclear Factor;; Erk1/Erk2 Mapk Signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; Inhibition of Cellular Proliferation by Gleevec;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; Overview of telomerase protein component gene hTert Transcriptional Regulation;; p38 MAPK Signaling Pathway;; Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy;; Telomeres, Telomerase, Cellular Aging, and Immortality;; Tumor Suppressor Arf Inhibits Ribosomal Biogenesis;; WNT Signaling Pathway Acute myeloid leukemia;; Bladder cancer;; Chronic myeloid leukemia;; Colorectal cancer;; Endometrial cancer;; ErbB signaling pathway;; Jak-STAT signaling pathway;; MAPK signaling pathway;; Pathways in cancer;; Small cell lung cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Environmental Information Process;; TGF-beta signaling pathway;; Thyroid cancer;; Wnt signaling pathway activation of caspase activity;; activation of pro-apoptotic gene products;; activation of pro-apoptotic gene products;; axon;; B cell apoptosis;; detection of mechanical stimulus involved in sensory perception of sound;; DNA binding;; DNA fragmentation involved in apoptosis;; induction of apoptosis by intracellular signals;; induction of apoptosis by intracellular signals;; middle ear morphogenesis;; negative regulation of protein binding;; negative regulation of specific transcription from RNA polymerase II promoter;; negative regulation of survival gene product expression;; negative regulation of survival gene product expression;; nuclear body;; nucleus;; nucleus;; pigmentation;; positive regulation of B cell apoptosis;; positive regulation of catalytic activity;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; protein binding;; protein processing;; regulation of apoptosis;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; release of cytochrome c from mitochondria;; response to alkaloid;; response to radiation;; response to radiation;; skeletal system morphogenesis;; spindle;; transcription;; transcription factor activity;; transcription regulator activity cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; pigmentation;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; catabolic process;; cell death;; cell proliferation;; cellular component disassembly;; cellular metabolic process;; detection of stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to chemical stimulus;; response to external stimulus;; system process 7047.1436 7061.6497 6869.3071 3218.3337 3571.3879 3668.6853 0.0022354063 1.00638 12.77152 11.76514 1345308 1425281_a_at X chrX:137074816-137075371 X F1 chrX:137074066-137077724 X F1 RSQ Mm.22216 NM_010286 2 1 14605 RP23-440B21.1 Tsc22d3 TSC22 domain family, member 3 (Tsc22d3), transcript variant 2, mRNA. anti-apoptosis;; regulation of transcription, DNA-dependent;; response to osmotic stress;; transcription factor activity binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell death;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to abiotic stimulus;; response to stress 489.8741 531.3741 449.5627 146.8204 163.7786 190.4401 0.00065296593 1.55851 8.93408 7.37557 1334833 1425351_at 2 chr2:151935679-151936227 2 G3 chr2:151931465-151937089 2 G3 RSQ Mm.218639 NM_029688 1 1 76650 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA. antioxidant activity;; ATP binding;; cytoplasm;; cytosol;; magnesium ion binding;; nucleotide binding;; oxidation reduction;; oxidoreductase activity;; response to oxidative stress;; sulfiredoxin activity cell;; cell part cell part;; intracellular;; intracellular part antioxidant activity;; binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity metabolic process;; response to stimulus oxidation reduction;; response to chemical stimulus;; response to stress 137.4483 161.0408 147.2714 38.7712 32.2961 48.6472 0.0034930636 1.91396 7.21212 5.29816 1334842 1425362_at 5 chr5:138104059-138104479 5 G2 chr5:138104037-138125921 5 G2 RSQ Mm.260869 NM_145566 1 1 231801 Agfg2 ArfGAP with FG repeats 2 (Agfg2), transcript variant 1, mRNA. ARF GTPase activator activity;; metal ion binding;; regulation of ARF GTPase activity;; zinc ion binding binding;; enzyme regulator activity enzyme activator activity;; ion binding;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 238.4329 294.7137 241.7933 87.8747 121.8584 79.4824 0.0061270902 1.43975 8.00608 6.56633 1334929 1425514_at 13 50.0 cM chr13:102453666-102454171 13 D1 chr13:102450715-102462602 13 D1 RSQ Mm.259333 NM_001024955 2 1 18708 Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 1, mRNA. AKT Signaling Pathway;; B Cell Survival Pathway;; Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK);; Corticosteroids and cardioprotection;; CTCF: First Multivalent Nuclear Factor;; CXCR4 Signaling Pathway;; EGF Signaling Pathway;; Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia;; Fc Epsilon Receptor I Signaling in Mast Cells;; Growth Hormone Signaling Pathway;; Human Cytomegalovirus and Map Kinase Pathways;; IGF-1 Signaling Pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages;; Influence of Ras and Rho proteins on G1 to S Transition;; Inhibition of Cellular Proliferation by Gleevec;; Insulin Signaling Pathway;; mTOR Signaling Pathway;; Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation;; Nerve growth factor pathway (NGF);; NFAT and Hypertrophy of the heart (Transcription in the broken heart);; PDGF Signaling Pathway;; Phospholipase C Signaling Pathway;; Phospholipids as signalling intermediaries;; PTEN dependent cell cycle arrest and apoptosis;; Rac 1 cell motility signaling pathway;; Ras Signaling Pathway;; Ras-Independent pathway in NK cell-mediated cytotoxicity;; Regulation of BAD phosphorylation;; Regulation of eIF4e and p70 S6 Kinase;; Role of ERBB2 in Signal Transduction and Oncology;; Role of Erk5 in Neuronal Survival;; Role of nicotinic acetylcholine receptors in the regulation of apoptosis;; Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration;; Signaling of Hepatocyte Growth Factor Receptor;; Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway;; T Cell Receptor Signaling Pathway;; The Co-Stimulatory Signal During T-cell Activation;; The IGF-1 Receptor and Longevity;; Thrombin signaling and protease-activated receptors;; TPO Signaling Pathway;; Transcription factor CREB and its extracellular signals;; Trefoil Factors Initiate Mucosal Healing;; Trka Receptor Signaling Pathway;; Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Acute myeloid leukemia;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Colorectal cancer;; Endometrial cancer;; ErbB signaling pathway;; Fc epsilon RI signaling pathway;; Focal adhesion;; Glioma;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Leukocyte transendothelial migration;; Melanoma;; mTOR signaling pathway;; Natural killer cell mediated cytotoxicity;; Neurotrophin signaling pathway;; Non-small cell lung cancer CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; VEGF signaling pathway [PATH:mmu04370] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Informatio;; Pancreatic cancer;; Pathways in cancer;; Phosphatidylinositol signaling system;; Prostate cancer;; Regulation of actin cytoskeleton;; Renal cell carcinoma;; Small cell lung cancer;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway;; Type II diabetes mellitus;; VEGF signaling pathway 1-phosphatidylinositol-3-kinase activity;; B cell differentiation;; cytoplasm;; cytosol;; insulin receptor substrate binding;; intracellular;; kinase activity;; membrane;; negative regulation of apoptosis;; negative regulation of apoptosis;; negative regulation of cell-matrix adhesion;; negative regulation of osteoclast differentiation;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; positive regulation of cell migration;; protein amino acid phosphorylation;; protein binding;; signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; catalytic activity;; enzyme regulator activity kinase regulator activity;; protein binding;; transferase activity biological adhesion;; biological regulation;; cellular process;; death;; developmental process;; immune system process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; cell activation;; cell adhesion;; cell communication;; cell death;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; immune system development;; leukocyte activation;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of localization;; regulation of locomotion;; regulation of multicellular organismal process 7601.7352 7438.6597 7528.0867 1933.6239 2923.1461 2082.8401 0.010975636 1.72542 12.87700 11.15158 1334990 1425631_at 19 chr19:36807805-36808192 19 C2 chr19:36806220-36811094 19 C2 RSQ Mm.24724 NM_016854 1 1 53412 Ppp1r3c protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen biosynthetic process;; glycogen metabolic process;; protein binding;; protein targeting binding protein binding cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport 2294.9077 2190.1389 2259.5349 649.2134 764.0944 680.9244 0.00083685428 1.69044 11.13428 9.44384 1345554 1425837_a_at 3 chr3:51055003-51055460 3 C chr3:51028368-51055576 3 C RSQ Mm.86541 NM_009834 2 2 12457 Ccrn4l CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA. Selective expression of chemokine receptors during T-cell polarization rhythmic process rhythmic process 887.8400 890.4088 845.8764 373.3417 355.3185 414.8619 0.0011256794 1.20099 9.77226 8.57127 1345648 1426004_a_at 2 89.0 cM chr2:157943001-157943415 2 H1 chr2:157942140-157972128 2 H1 RSQ Mm.330731 NM_009373 1 1 21817 RP23-396G1.2 Tgm2 transglutaminase 2, C polypeptide (Tgm2), mRNA. Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 591.7321 488.5075 601.5047 277.7883 268.7697 224.8080 0.0011437022 1.12428 9.12449 8.00021 1345779 1426210_x_at 9 F1 chr9:106373029-106373498 9 F1 UG5 Mm.273659 235587 Parp3 NAD+ ADP-ribosyltransferase 3 PARP-3 Base excision repair CLASS Genetic Information Processing; Replication and Repair; Base excision repair [PATH:mmu03410] transferase activity catalytic activity transferase activity 4148.3515 4008.6530 4122.3605 1741.8214 1744.9808 1552.3649 0.00099112834 1.28695 11.99883 10.71188 1345786 1426235_a_at 1 chr1:155754454-155755308 1 G3 chr1:155747074-155756844 1 G3 RSQ Mm.210745 NM_008131 1 1 14645 Glul glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA. Alanine, aspartate and glutamate metabolism;; Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan biosynthesis [PATH:mmu0;; Nitrogen metabolism;; Peptidoglycan biosynthesis ATP binding;; catalytic activity;; cytoplasm;; glutamate-ammonia ligase activity;; glutamine biosynthetic process;; intracellular;; ligase activity;; mitochondrion;; nitrogen compound metabolic process;; nucleotide binding;; response to glucose stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to chemical stimulus 6927.6529 6899.3741 6905.6186 2746.8536 2554.6209 2686.6089 0.00048649192 1.37664 12.75465 11.37801 1345787 1426236_a_at 1 chr1:155756223-155756784 1 G3 chr1:155747074-155756844 1 G3 RSQ Mm.210745 NM_008131 1 1 14645 Glul glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA. Alanine, aspartate and glutamate metabolism;; Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan biosynthesis [PATH:mmu0;; Nitrogen metabolism;; Peptidoglycan biosynthesis ATP binding;; catalytic activity;; cytoplasm;; glutamate-ammonia ligase activity;; glutamine biosynthetic process;; intracellular;; ligase activity;; mitochondrion;; nitrogen compound metabolic process;; nucleotide binding;; response to glucose stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to chemical stimulus 177.4953 205.9852 191.7385 74.0406 90.4069 97.7283 0.0034030352 1.14057 7.58034 6.43977 1335426 1426446_at 8 chr8:122686736-122687249 8 E1 chr8:122669128-122687318 8 E1 RSQ Mm.101958 NM_172286 1 1 234797 6430548M08Rik RIKEN cDNA 6430548M08 gene (6430548M08Rik), mRNA. 328.8571 323.8853 319.5995 140.8127 159.8146 116.5186 0.010865646 1.23282 8.34026 7.10744 1345886 1426599_a_at 4 52.0 cM chr4:118809597-118809803 4 D2.1 chr4:118781349-118809935 4 D2.1 RSQ Mm.21002 NM_011400 1 1 20525 RP23-344D2.2 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA. Vitamin C in the Brain Adipocytokine signaling pathway;; Pathways in cancer;; Renal cell carcinoma CLASS Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Renal cell carcinoma [PATH:mmu05211] basolateral plasma membrane;; carbohydrate transport;; cytoplasm;; glucose transmembrane transporter activity;; glucose transport;; integral to membrane;; intracellular;; membrane;; plasma membrane;; protein binding;; substrate-specific transmembrane transporter activity;; sugar:hydrogen symporter activity;; transmembrane transport;; transport;; transporter activity cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part binding;; transporter activity protein binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 352.4387 343.3140 339.0303 181.9101 182.8125 149.6226 0.0073006463 1.01447 8.42996 7.41550 1335530 1426600_at 4 52.0 cM chr4:118809340-118809699 4 D2.1 chr4:118781349-118809935 4 D2.1 RSQ Mm.21002 NM_011400 1 1 20525 RP23-344D2.2 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA. Vitamin C in the Brain Adipocytokine signaling pathway;; Pathways in cancer;; Renal cell carcinoma CLASS Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Renal cell carcinoma [PATH:mmu05211] basolateral plasma membrane;; carbohydrate transport;; cytoplasm;; glucose transmembrane transporter activity;; glucose transport;; integral to membrane;; intracellular;; membrane;; plasma membrane;; protein binding;; substrate-specific transmembrane transporter activity;; sugar:hydrogen symporter activity;; transmembrane transport;; transport;; transporter activity cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part binding;; transporter activity protein binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 2767.8784 2928.2458 2883.4929 1160.3472 1503.3043 1074.1431 0.012518606 1.21358 11.48133 10.26774 1335613 1426722_at 15 chr15:96517875-96518403 15 F1 chr15:96517822-96530129 15 F1 RSQ Mm.46754 NM_175121 1 1 67760 Slc38a2 solute carrier family 38, member 2 (Slc38a2), mRNA. amino acid transmembrane transporter activity;; amino acid transport;; integral to membrane;; ion transport;; membrane;; plasma membrane;; sodium ion binding;; sodium ion transport;; symporter activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 501.1893 505.0569 492.6994 259.2585 183.5748 210.0638 0.013594973 1.21364 8.96469 7.75105 1335676 1426808_at 14 chr14:47993534-48005842 14 C1 RSQ Mm.248615 NM_010705 2 1 16854 Lgals3 lectin, galactose binding, soluble 3 (Lgals3), transcript variant 2, mRNA. cell differentiation;; cytoplasm;; cytoplasm;; extracellular matrix organization;; IgE binding;; nucleus;; nucleus;; protein binding;; proteinaceous extracellular matrix;; skeletal system development;; sugar binding cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding carbohydrate binding;; protein binding cellular component organization;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; cellular developmental process;; extracellular structure organization;; multicellular organismal development 2348.5110 2284.7302 2262.4852 298.5240 403.2400 434.4057 0.0036942953 2.61964 11.16634 8.54670 1345965 1426875_s_at 2 chr2:151936530-151936918 2 G3 chr2:151931465-151937089 2 G3 RSQ Mm.218639 NM_029688 1 1 76650 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA. antioxidant activity;; ATP binding;; cytoplasm;; cytosol;; magnesium ion binding;; nucleotide binding;; oxidation reduction;; oxidoreductase activity;; response to oxidative stress;; sulfiredoxin activity cell;; cell part cell part;; intracellular;; intracellular part antioxidant activity;; binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity metabolic process;; response to stimulus oxidation reduction;; response to chemical stimulus;; response to stress 824.8623 881.4139 880.7285 275.9297 305.0408 210.5749 0.0067268382 1.72501 9.75141 8.02640 1335747 1426900_at 10 chr10:66718474-66719018 10 B5.1 chr10:66590005-66719074 10 B5.1 RSQ NM_207221 1 1 108829 Jmjd1c jumonji domain containing 1C (Jmjd1c), mRNA. chromatin modification;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 176.4817 201.7630 165.4852 80.9674 98.7038 90.2534 0.0010238222 1.01008 7.49682 6.48674 1335839 1427013_at 4 chr4:43526033-43526572 4 B1 chr4:43519897-43526597 4 B1 RSQ Mm.283682 NM_139305 1 1 230099 RP23-195K8.9 Car9 carbonic anhydrase 9 (Car9), mRNA. Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] carbonate dehydratase activity;; cell projection;; integral to membrane;; lyase activity;; membrane;; metal ion binding;; morphogenesis of an epithelium;; one-carbon metabolic process;; plasma membrane;; secretion;; zinc ion binding cell;; cell part cell part;; cell projection;; membrane;; membrane part binding;; catalytic activity ion binding;; lyase activity cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process anatomical structure development;; anatomical structure morphogenesis;; cellular metabolic process;; establishment of localization;; multicellular organismal development;; transport 534.1822 551.9059 548.0636 221.0183 250.4959 167.3495 0.014789219 1.37476 9.08922 7.71446 1335858 1427035_at 14 chr14:70703392-70703860 14 D2 chr14:70703273-70748240 14 D2 RSQ Mm.270647 NM_001135152 3 1 213053 Slc39a14 solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 2, mRNA. ferrous iron transmembrane transporter activity;; integral to membrane;; ion transport;; iron ion transport;; membrane;; metal ion transmembrane transporter activity;; metal ion transport;; plasma membrane;; transport;; zinc ion binding;; zinc ion transmembrane transporter activity;; zinc ion transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 438.6790 394.5662 411.1236 254.8679 182.5828 164.1519 0.025304039 1.07322 8.69486 7.62163 1335950 1427151_at 2 chr2:104594972-104595534 2 E2 chr2:104594951-104656853 2 E2 RSQ Mm.274314 NM_001123327 1 1 99003 RP24-297H17.9 Qser1 glutamine and serine rich 1 (Qser1), mRNA. 1413.5184 1418.8636 1415.4694 677.2941 673.5686 594.2561 0.0029469708 1.12947 10.46755 9.33809 1346056 1427345_a_at 7 F3|7 4.0 cM chr7:133816668-133817069 7 F3 UGA Mm.368982 20887 Sult1a1 Sulfotransferase family 1A, phenol-preferring, member 1 (Sult1a1), mRNA Sulfur metabolism CLASS Metabolism; Energy Metabolism; Sulfur metabolism [PATH:mmu00920] aryl sulfotransferase activity;; cytoplasm;; lipid metabolic process;; nucleotide binding;; steroid metabolic process;; sulfotransferase activity;; transferase activity;; tyrosine-ester sulfotransferase activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity nucleotide binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 202.6882 190.8554 191.8526 73.4948 82.6194 94.4255 0.0046550118 1.23141 7.60777 6.37636 1336117 1427363_at 15 chr15:25567455-25567955 15 B1 UG5 Mm.450192 Mus musculus, clone IMAGE:3584279, mRNA 512.9620 520.0769 505.7236 115.6528 154.0563 153.8371 0.0050888062 1.87375 9.00250 7.12874 1336304 1427638_at 9 23.0 cM chr9:48462401-48644050 9 A5.3 RSQ Mm.457803 NM_001033324 1 1 235320 Zbtb16 zinc finger and BTB domain containing 16 (Zbtb16), mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer anterior/posterior pattern formation;; DNA binding;; embryonic hindlimb morphogenesis;; embryonic limb morphogenesis;; embryonic pattern specification;; forelimb morphogenesis;; leg morphogenesis;; male germ-line stem cell division;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of transcription, DNA-dependent;; nucleus;; nucleus;; positive regulation of apoptosis;; protein binding;; protein binding;; regulation of transcription;; skeletal system development;; specific transcriptional repressor activity;; transcriptional repressor complex;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription repressor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; sexual reproduction 63.7484 77.4995 54.6763 34.1613 27.3026 28.2637 0.0047284267 1.11905 6.01443 4.89538 1336323 1427683_at 10 35.0 cM chr10:67004377-67004801 10 B5.1 chr10:67000616-67004936 10 B5.1 RSQ Mm.290421 NM_010118 1 1 13654 Egr2 early growth response 2 (Egr2), mRNA. Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells brain segmentation;; DNA binding;; facial nerve structural organization;; intracellular;; metal ion binding;; motor axon guidance;; myelination;; nucleic acid binding;; nucleus;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; regulation of ossification;; regulation of transcription;; regulation of transcription, DNA-dependent;; rhombomere 3 development;; rhombomere 3 formation;; rhombomere 5 formation;; rhythmic behavior;; rhythmic behavior;; Schwann cell differentiation;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular component organization;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus;; rhythmic process anatomical structure arrangement;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; ensheathment of neurons;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; ossification;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; rhythmic behavior;; system process;; tissue remodeling 837.3812 754.2167 840.8943 274.4554 330.3940 419.8076 0.013555441 1.26743 9.66145 8.39402 1346211 1427742_a_at 13 chr13:5864257-5866575 13 A1 chr13:5860734-5869639 13 A1 RSQ Mm.275036 NM_011803 1 1 23849 Klf6 Kruppel-like factor 6 (Klf6), mRNA. cytokine-mediated signaling pathway;; cytoplasm;; DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 619.3721 605.6988 652.3240 36.6971 50.5820 47.1409 0.00083893737 3.81650 9.28885 5.47235 1346214 1427747_a_at 2 27.0 cM chr2:32240946-32241323 2 B chr2:32240156-32243259 2 B RSQ Mm.9537 NM_008491 1 1 16819 RP23-161B9.11 Lcn2 lipocalin 2 (Lcn2), mRNA. binding;; extracellular region;; response to virus;; transport;; transporter activity extracellular region binding;; transporter activity establishment of localization;; localization;; multi-organism process;; response to stimulus establishment of localization;; response to biotic stimulus;; response to other organism;; transport 5457.8172 5366.7867 5325.4095 2285.0649 2958.9112 1856.9451 0.024513423 1.21168 12.39421 11.18253 1346320 1428116_a_at 17 A1|17 3.1 cM UG5 Mm.1948 21648 Dynlt1 Dynein light chain Tctex-type 1 (Dynlt1), mRNA axonemal dynein complex;; cytoplasmic dynein complex;; cytoplasmic dynein complex;; dynein complex;; Golgi apparatus;; microtubule;; microtubule-based process;; motor activity;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part axoneme;; axoneme part;; cell part;; cell projection;; cell projection part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity hydrolase activity;; protein binding cellular process microtubule-based process 2022.3901 2068.3186 2083.5964 313.0404 399.7279 277.0665 0.0032257794 2.65793 11.00698 8.34906 1336689 1428306_at 10 chr10:59412481-59412957 10 B4 chr10:59412422-59414518 10 B4 RSQ Mm.21697 NM_029083 1 1 74747 Ddit4 DNA-damage-inducible transcript 4 (Ddit4), mRNA. mTOR signaling pathway CLASS Environmental Information Processing; Signal Transduction; mTOR signaling pathway [PATH:mmu04150] apoptosis;; cytoplasm;; negative regulation of signal transduction cell;; cell part cell part;; intracellular;; intracellular part biological regulation;; cellular process;; death;; negative regulation of biological process;; regulation of biological process cell communication;; cell death;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 568.2269 576.4340 533.3693 117.3760 140.0004 154.3352 0.0016525242 2.03537 9.12678 7.09140 1336820 1428776_at 5 E5 chr5:104034768-104035330 5 E5 UGA Mm.7446 75750 Slc10a6 Solute carrier family 10 (sodium/bile acid cotransporter family), member 6 (Slc10a6), mRNA bile acid:sodium symporter activity;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; symporter activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 23774.9245 24576.4852 24517.5964 1109.7352 1748.1001 864.5223 0.0045445599 4.35345 14.56789 10.21444 1336865 1428942_at 8 45.0 cM chr8:96696756-96697386 8 C5 chr8:96696517-96697467 8 C5 RSQ Mm.147226 NM_008630 1 1 17750 Mt2 metallothionein 2 (Mt2), mRNA. cellular zinc ion homeostasis;; detoxification of copper ion;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 216.9852 218.3053 220.3186 109.6967 105.6673 104.8300 0.00011858369 1.03415 7.77170 6.73756 1336880 1429033_at 6 chr6:28366904-28367275 6 A3.3 chr6:28366690-28371724 6 A3.3 RSQ Mm.332950 NM_028900 1 1 74375 Gcc1 golgi coiled coil 1 (Gcc1), mRNA. cytoplasm;; Golgi apparatus;; membrane cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle 670.9358 665.8286 661.9893 302.0964 283.7407 288.3186 0.00031795607 1.19363 9.37990 8.18627 1346830 1432273_a_at 1 94.0 cM chr1:175262194-175262805 1 H3 chr1:175262016-175263634 1 H3 RSQ Mm.6393 NM_010045 1 1 13349 Darc Duffy blood group, chemokine receptor (Darc), mRNA. G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; inflammatory response;; integral to membrane;; membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; regulation of biological process;; regulation of cellular process;; response to external stimulus;; response to stress 2847.0386 2696.2835 2722.9379 1017.3076 1076.6768 1022.8797 2.5780386e-06 1.40721 11.42765 10.02044 1346897 1433428_x_at 2 H1|2 89.0 cM chr2:157942194-157942355 2 H1 UG5 Mm.330731 21817 RP23-396G1.2 Tgm2 Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943) Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 974.7395 956.1341 1000.0866 552.6467 443.2162 428.4884 0.010269835 1.05022 9.93195 8.88173 1337260 1433508_at 13 chr13:5869083-5869514 13 A1 chr13:5860734-5869639 13 A1 RSQ Mm.275036 NM_011803 1 1 23849 Klf6 Kruppel-like factor 6 (Klf6), mRNA. cytokine-mediated signaling pathway;; cytoplasm;; DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 16712.9199 16491.4865 16951.9314 6703.5269 9168.6632 6819.5502 0.015172351 1.15954 14.02909 12.86955 1337327 1433691_at 19 chr19:36806257-36806814 19 C2 chr19:36806220-36811094 19 C2 RSQ Mm.24724 NM_016854 1 1 53412 Ppp1r3c protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen biosynthetic process;; glycogen metabolic process;; protein binding;; protein targeting binding protein binding cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport 304.0789 318.9772 314.8499 133.9854 148.4707 121.2928 0.0031344187 1.22061 8.28804 7.06744 1346968 1433757_a_at 14 B chr14:31998914-31999067 14 B UG5 Mm.298728 64652 Nisch Imidazoline receptor I-1-like protein actin cytoskeleton organization;; apoptosis;; cell communication;; cytoplasm;; cytosol;; endosome;; integrin binding;; membrane;; negative regulation of cell migration;; phosphoinositide binding;; plasma membrane;; protein binding;; Rac protein signal transduction;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity lipid binding;; protein binding;; signal transducer activity biological regulation;; cellular component organization;; cellular process;; death;; localization;; locomotion;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cell death;; cell motility;; cell motion;; localization of cell;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion 964.1025 891.5964 967.6248 263.7380 272.2267 230.5185 0.00017946645 1.88374 9.87720 7.99346 1337418 1434025_at 14 chr14:99713709-99714191 14 E2.2 UGA Mm.441332 Transcribed locus 106.8924 114.4313 121.9852 48.3935 66.0574 57.9822 0.0081414923 1.00300 6.83631 5.83331 1337634 1434752_at 11 UGA Mm.440925 Transcribed locus 533.5974 489.0088 539.4488 174.5533 198.2024 154.3803 0.0013319039 1.57332 9.02289 7.44957 1347098 1434773_a_at 4 52.0 cM chr4:118809715-118809927 4 D2.1 chr4:118781349-118809935 4 D2.1 RSQ Mm.21002 NM_011400 1 1 20525 RP23-344D2.2 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA. Vitamin C in the Brain Adipocytokine signaling pathway;; Pathways in cancer;; Renal cell carcinoma CLASS Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Renal cell carcinoma [PATH:mmu05211] basolateral plasma membrane;; carbohydrate transport;; cytoplasm;; glucose transmembrane transporter activity;; glucose transport;; integral to membrane;; intracellular;; membrane;; plasma membrane;; protein binding;; substrate-specific transmembrane transporter activity;; sugar:hydrogen symporter activity;; transmembrane transport;; transport;; transporter activity cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part binding;; transporter activity protein binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 1073.9590 1008.7879 1047.2931 454.3997 392.3883 313.9057 0.0097103876 1.44715 10.02653 8.57938 1347155 1435137_s_at IPA 1200015M12Rik RIKEN cDNA 1200015M12 gene 50.4564 71.2900 67.3881 29.6627 33.2077 29.4021 0.013681779 1.02171 5.96234 4.94063 1337862 1435767_at 9 chr9:40098621-40099186 9 A5.1 chr9:40076800-40099203 9 A5.1 RSQ Mm.290083 NM_001083917 3 1 235281 Scn3b sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; sodium channel activity;; sodium ion binding;; sodium ion transport;; transport;; voltage-gated ion channel activity cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 891.6459 850.0964 910.1074 508.6380 411.7681 308.9224 0.02992099 1.13814 9.78723 8.64909 1347378 1436750_a_at 15 chr15:4103756-4103890 15 A1 chr15:3976427-4105344 15 A1 RSQ Mm.13445 NM_024188 1 1 67041 Oxct1 3-oxoacid CoA transferase 1 (Oxct1), nuclear gene encoding mitochondrial protein, mRNA. Butanoate metabolism CLASS Metabolism; Carbohydrate Metabolism; Butanoate metabolism [PATH:mmu00650] Metabolism; Lipid Metabolism; Synthesis and degradation of ketone bodies [PATH:mmu00072] Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine degradation [PATH:mmu00280];; Synthesis and degradation of ketone bodies;; Valine, leucine and isoleucine degradation 3-oxoacid CoA-transferase activity;; cellular ketone body metabolic process;; CoA-transferase activity;; ketone body catabolic process;; metabolic process;; mitochondrion;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process catabolic process;; cellular metabolic process 340.2855 327.0920 363.5089 143.2012 182.3139 190.1718 0.0092771147 1.00889 8.42333 7.41445 1338064 1436910_at 1 chr1:159106227-159122987 1 H1 chr1:159065313-159342726 1 H1 RSQ Mm.235028 NM_177644 1 1 226525 Rasal2 RAS protein activator like 2 (Rasal2), mRNA. 367.2300 341.8913 373.3779 108.6035 132.3108 206.8868 0.038096902 1.32634 8.49414 7.16780 1338102 1437110_at 6 chr6:149274479-149274895 6 G3 chr6:149257935-149284185 6 G3 RSQ Mm.333515 NM_026054 1 1 67246 RP23-214L4.1 2810474O19Rik RIKEN cDNA 2810474O19 gene (2810474O19Rik), mRNA. 4093.1354 3995.7787 3926.6895 1381.2200 1528.2908 1563.0686 0.00060160607 1.42758 11.96745 10.53987 1347528 1437277_x_at 2 H1|2 89.0 cM chr2:157942194-157942355 2 H1 UGA Mm.330731 21817 RP23-396G1.2 Tgm2 Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943) Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 251.4493 255.2963 243.1144 113.0870 141.7079 114.4788 0.0084014882 1.02955 7.96521 6.93567 1338164 1437543_at 3 H3|3 70.5 cM chr3:151886597-151887090 3 H3 UGA Mm.278922 51886 Fubp1 Far upstream element (FUSE) binding protein 1 (Fubp1), mRNA DNA binding;; nucleus;; regulation of transcription, DNA-dependent;; RNA binding;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 160.7681 150.3015 154.8941 67.9840 77.3686 60.0200 0.0051806009 1.18917 7.27856 6.08939 1338271 1438234_at 1 chr1:183107981-183108368 1 H4 UGA Mm.441222 Transcribed locus, strongly similar to XP_573529.1 PREDICTED: similar to WD-repeat protein 26 [Rattus norvegicus] 1706.4576 1657.5697 1696.3744 911.0775 799.9846 639.6704 0.01663894 1.12115 10.71996 9.59881 1347820 1438385_s_at 8 C3 chr8:88051301-88051346 8 C3 UGA Mm.200423 108682 Gpt2 Glutamic pyruvate transaminase (alanine aminotransferase) 2, mRNA (cDNA clone MGC:37704 IMAGE:5065322) Alanine, aspartate and glutamate metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] biosynthetic process;; catalytic activity;; L-alanine:2-oxoglutarate aminotransferase activity;; pyridoxal phosphate binding;; transaminase activity;; transferase activity;; transferase activity, transferring nitrogenous groups binding;; catalytic activity cofactor binding;; lipid binding;; transferase activity;; vitamin binding metabolic process biosynthetic process 2907.7630 2772.5652 2929.5266 1377.8717 1524.7609 1254.5803 0.0032672519 1.05452 11.48638 10.43186 1338298 1438443_at 16 chr16:43621146-43621629 16 B4 UGA Mm.441121 Transcribed locus 295.8198 304.4948 300.6182 153.2075 171.1235 128.5411 0.013397081 1.00211 8.23021 7.22811 1347844 1438511_a_at 14 D3 chr14:79688584-79688641 14 D3 UGA Mm.29811 66214 1190002H23Rik Response gene to complement 32 cell cycle;; cytoplasm;; nucleus;; protein binding;; protein kinase activator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; enzyme regulator activity enzyme activator activity;; kinase regulator activity;; protein binding cellular process cell cycle 337.9409 350.7296 354.1087 109.2104 109.3411 104.9861 4.8854375e-07 1.68839 8.44096 6.75257 1338349 1438758_at 12 A1.3 IPA AL024210 expressed sequence AL024210 2467.8406 2460.9639 2444.3414 682.8227 923.0777 646.1873 0.0084087856 1.72926 11.26309 9.53383 1348119 1442025_a_at 9 chr9:48459944-48460104 9 A5.3 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 538.5243 592.7676 552.8870 185.5547 199.8664 167.1166 0.00025969455 1.61058 9.13168 7.52110 1338484 1442026_at 9 chr9:48460144-48460494 9 A5.3 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 230.4859 269.2463 220.0104 87.9013 122.0303 115.7237 0.0050191107 1.15310 7.90092 6.74782 1338563 1445689_at 2 chr2:60795842-60796113 2 C1.2 UGA Mm.441870 Transcribed locus 1031.9227 1059.9033 1031.4726 428.3029 427.6436 395.6834 0.00024973383 1.32012 10.02378 8.70365 1338758 1448199_at 8 chr8:11611781-11612172 8 A1.1 chr8:11611582-11635689 8 A1.1 RSQ Mm.12459 NM_133971 1 1 102334 Ankrd10 ankyrin repeat domain 10 (Ankrd10), mRNA. 701.3741 689.6571 710.4279 301.6247 293.6408 255.3364 0.0026032491 1.30852 9.45211 8.14359 1338766 1448208_at 8 chr8:81862536-81862882 8 C2 chr8:81862293-81923367 8 C2 RSQ Mm.223717 NM_008539 1 1 17125 Smad1 MAD homolog 1 (Drosophila) (Smad1), mRNA. CTCF: First Multivalent Nuclear Factor TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] BMP signaling pathway;; BMP signaling pathway;; BMP signaling pathway;; cytoplasm;; gamete generation;; hindbrain development;; homeostatic process;; inflammatory response;; intracellular;; MAPKKK cascade;; mesodermal cell fate commitment;; midbrain development;; negative regulation of cell proliferation;; nucleus;; osteoblast fate commitment;; positive regulation of gene expression;; positive regulation of osteoblast differentiation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; RNA polymerase II transcription factor activity;; transcription;; transcription factor activity;; transcription factor complex;; transforming growth factor beta receptor signaling pathway cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; nitrogen compound metabolic process;; ossification;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive process;; response to external stimulus;; response to stress;; sexual reproduction;; tissue remodeling 937.9363 907.0593 917.7051 291.7402 259.9207 266.0375 0.00037990509 1.75811 9.84676 8.08865 1338782 1448231_at 17 13.0 cM chr17:28537316-28537865 17 A3.3 chr17:28536039-28623057 17 A3.3 RSQ Mm.276405 NM_010220 1 1 14229 Fkbp5 FK506 binding protein 5 (Fkbp5), mRNA. binding;; cytoplasm;; isomerase activity;; nucleus;; peptidyl-prolyl cis-trans isomerase activity;; protein binding;; protein folding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 140.7088 132.2740 130.4158 60.6229 57.3469 54.0472 6.8476556e-05 1.23045 7.07031 5.83986 1348183 1448232_x_at 15 chr15:98868416-98868515 15 F1 chr15:98860321-98868536 15 F1 RSQ Mm.477500 NM_009448 3 2 22146 Tuba1c tubulin, alpha 1C (Tuba1c), mRNA. Gap junction CLASS Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] GTP binding;; GTPase activity;; microtubule;; microtubule-based movement;; microtubule-based process;; nucleotide binding;; protein complex;; protein polymerization;; structural molecule activity cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity hydrolase activity;; nucleotide binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process cellular component assembly;; cellular macromolecular complex subunit organization;; macromolecular complex subunit organization;; microtubule-based process;; protein complex biogenesis 4229.9804 4101.1907 3888.3464 722.9115 1312.3741 874.7988 0.012793634 2.11492 11.99107 9.87615 1338812 1448272_at 1 71.0 cM chr1:135972093-135972484 1 E4 chr1:135971441-135975732 1 E4 RSQ Mm.392646 NM_007570 1 1 12227 Btg2 B-cell translocation gene 2, anti-proliferative (Btg2), mRNA. BTG family proteins and cell cycle regulation anterior/posterior pattern formation;; negative regulation of apoptosis;; neuron differentiation;; protein amino acid methylation;; protein binding;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; transcription binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to stress 639.9896 589.0408 676.0721 143.7794 116.8419 143.0304 0.00017992311 2.24295 9.30839 7.06544 1338857 1448328_at 5 chr5:34905699-34906233 5 B2 chr5:34892336-34906288 5 B2 RSQ Mm.5012 NM_001136088 4 1 24055 Sh3bp2 SH3-domain binding protein 2 (Sh3bp2), transcript variant d, mRNA. Natural killer cell mediated cytotoxicity CLASS Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] protein binding;; SH3 domain binding binding protein binding 1709.4891 1715.6037 1689.0408 614.3341 808.7623 584.2388 0.011099108 1.36432 10.73528 9.37096 1339017 1448529_at 2 84.0 cM chr2:148230231-148230761 2 G3 chr2:148230206-148233924 2 G3 RSQ Mm.24096 NM_009378 1 1 21824 RP23-70N3.2 Thbd thrombomodulin (Thbd), mRNA. Complement and coagulation cascades CLASS Cellular Processes; Immune System; Complement and coagulation cascades [PATH:mmu04610] binding;; blood coagulation;; calcium ion binding;; embryonic development;; female pregnancy;; integral to membrane;; membrane;; negative regulation of coagulation;; plasma membrane;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity ion binding;; signal transducer activity biological regulation;; developmental process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus coagulation;; embryonic development;; female pregnancy;; multicellular organismal development;; negative regulation of biological process;; negative regulation of multicellular organismal process;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of multicellular organismal process;; reproductive process;; response to external stimulus;; response to stress 1230.2147 1169.5646 1136.2792 495.1049 180.4638 363.2432 0.047666364 1.88487 10.20218 8.31732 1339177 1448724_at 9 59.0 cM chr9:107203813-107204254 9 F1 chr9:107199019-107204292 9 F1 RSQ Mm.4592 NM_009895 1 1 12700 Cish cytokine inducible SH2-containing protein (Cish), mRNA. Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of signal transduction;; plasma membrane;; protein binding;; regulation of growth cell;; cell part cell part;; membrane binding protein binding biological regulation;; cellular process;; growth;; metabolic process;; negative regulation of biological process;; regulation of biological process catabolic process;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of molecular function 298.0408 267.8551 293.0408 47.8600 35.7223 41.2122 0.00054135068 2.79171 8.15988 5.36817 1339204 1448756_at 3 43.6 cM chr3:90496586-90499210 3 F1 chr3:90496554-90499613 3 F1 RSQ Mm.2128 NM_009114 1 1 20202 S100a9 S100 calcium binding protein A9 (calgranulin B) (S100a9), mRNA. actin cytoskeleton reorganization;; calcium ion binding;; leukocyte chemotaxis;; regulation of integrin biosynthetic process binding ion binding biological regulation;; cellular component organization;; cellular process;; immune system process;; localization;; locomotion;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; behavior;; biosynthetic process;; cell motility;; cell motion;; cellular response to stimulus;; leukocyte migration;; localization of cell;; macromolecule metabolic process;; membrane organization;; organelle organization;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to external stimulus;; taxis 1971.4966 1773.0059 2009.9297 204.7138 348.6047 639.0388 0.03470996 2.42244 10.90333 8.48089 1348292 1448793_a_at 2 94.0 cM chr2:164251028-164251505 2 H3 chr2:164249746-164268688 2 H3 RSQ Mm.477724 NM_011521 1 1 20971 RP23-462O16.6 Sdc4 syndecan 4 (Sdc4), mRNA. Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514];; ECM-receptor interaction cell surface;; cytoskeletal protein binding;; integral to membrane;; membrane cell;; cell part cell part;; cell surface;; membrane;; membrane part binding protein binding 5293.7720 5588.1837 5506.6385 1854.0559 2458.4886 1991.9136 0.0061461756 1.38841 12.41507 11.02665 1339463 1449073_at 6 8.5 cM chr6:29411311-29411636 6 A3.3 chr6:29383152-29411888 6 A3.3 RSQ Mm.39046 NM_001081185 1 1 68794 Flnc filamin C, gamma (Flnc), mRNA. Focal adhesion CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510];; MAPK signaling pathway actin binding;; actin cytoskeleton;; actin filament-based process;; cytoplasm;; cytoskeleton;; membrane;; muscle fiber development cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; non-membrane-bounded organelle binding protein binding cellular process;; developmental process;; multicellular organismal process actin filament-based process;; anatomical structure development;; cellular developmental process;; multicellular organismal development 1357.4297 1401.0964 1387.2701 508.1839 638.2004 739.6995 0.017572764 1.15306 10.43235 9.27929 1339476 1449089_at 16 chr16:76291166-76291540 16 C3.1 chr16:76291106-76373294 16 C3.1 RSQ Mm.455873 NM_173440 1 1 268903 Nrip1 nuclear receptor interacting protein 1 (Nrip1), mRNA. histone deacetylase binding;; histone deacetylase complex;; lipid storage;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; ovarian follicle rupture;; ovulation;; protein binding;; receptor activity;; receptor binding;; regulation of transcription, DNA-dependent;; retinoid X receptor binding;; transcription;; transcription corepressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity protein binding;; signal transducer activity;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; biosynthetic process;; cellular metabolic process;; gamete generation;; macromolecule localization;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 472.4270 433.4186 474.8078 231.8657 185.9429 203.6540 0.0019458581 1.15631 8.84492 7.68861 1339494 1449109_at 10 52.0 cM chr10:94875126-94875560 10 C2 chr10:94874675-94879455 10 C2 RSQ Mm.474283 NM_007706 3 3 216233 Socs2 suppressor of cytokine signaling 2 (Socs2), mRNA. Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 780.2635 668.3992 692.9613 256.3480 266.2402 213.4880 0.00041544803 1.54415 9.47634 7.93219 1339561 1449188_at 10 chr10:79620535-79621046 10 C1 chr10:79611034-79621112 10 C1 RSQ Mm.143813 NM_021565 1 1 59090 Midn midnolin (Midn), mRNA. nucleolus;; nucleus cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part 205.7295 232.4871 211.9745 64.7201 91.0691 109.3914 0.021986489 1.32499 7.75779 6.43280 1339662 1449311_at 16 C3.3 chr16:87730397-87730943 16 C3.3 UGA Mm.26147 12013 Bach1 BTB and CNC homology 1 (Bach1), mRNA DNA binding;; nucleus;; protein binding;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 131.0401 129.7113 119.1671 52.5747 48.2263 48.3011 2.3441936e-05 1.34928 6.98329 5.63401 1339699 1449360_at 15 43.3 cM chr15:78112991-78113449 15 E1 chr15:78112939-78128810 15 E1 RSQ Mm.1940 NM_007781 1 1 12984 Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) (Csf2rb2), mRNA. Regulation of BAD phosphorylation Apoptosis;; Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] cytokine receptor activity;; cytokine-mediated signaling pathway;; integral to membrane;; membrane;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 2059.0425 2041.1732 1989.7122 329.2998 907.7075 586.1713 0.04804646 1.85892 10.98709 9.12817 1339701 1449363_at 1 103.2 cM chr1:192994277-192994768 1 H6 chr1:192994174-193007212 1 H6 RSQ Mm.2706 NM_007498 1 1 11910 Atf3 activating transcription factor 3 (Atf3), mRNA. DNA binding;; gluconeogenesis;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex;; transcription repressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1441.2160 1450.5048 1459.3252 419.6539 284.7226 238.2511 0.011280511 2.24790 10.50217 8.25427 1339832 1449519_at 6 chr6:66985453-66985671 6 C1 chr6:66985089-66987401 6 C1 RSQ Mm.389750 NM_007836 1 1 13197 Gadd45a growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), mRNA. ATM Signaling Pathway;; Cell Cycle: G2/M Checkpoint;; p53 Signaling Pathway Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] cell cycle;; cell cycle arrest;; centrosome cycle;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cellular metabolic process;; microtubule-based process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function;; response to stress 1344.6797 1323.8787 1305.1138 722.2324 744.6637 522.1836 0.024468501 1.01613 10.37119 9.35506 1348480 1449731_s_at 12 chr12:56590515-56590785 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 435.5230 427.4124 400.0377 67.9608 81.2033 74.3901 9.170108e-05 2.50098 8.71669 6.21571 1348516 1449901_a_at 4 chr4:132807657-132808759 4 D2.3 chr4:132796732-132808843 4 D2.3 RSQ Mm.36640 NM_016693 1 1 53608 Map3k6 mitogen-activated protein kinase kinase kinase 6 (Map3k6), mRNA. MAPKinase Signaling Pathway MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] ATP binding;; kinase activity;; magnesium ion binding;; MAP kinase kinase kinase activity;; metal ion binding;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity;; molecular transducer activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 106.6690 107.0012 126.8132 60.6148 42.4420 56.0859 0.0078711707 1.10882 6.82168 5.71286 1340074 1449906_at 1 86.6 cM chr1:166074030-166079220 1 H2.2 chr1:166053831-166079876 1 H2.2 RSQ Mm.3337 NM_011347 1 1 20344 Selp selectin, platelet (Selp), mRNA. Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 40.5499 57.1793 33.6230 15.0211 16.1647 18.6145 0.015315876 1.36945 5.41681 4.04735 1340126 1449984_at 5 E1|5 51.0 cM UGA Mm.4979 20310 Cxcl2 Chemokine (C-X-C motif) ligand 2 (Cxcl2), mRNA Chemokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062];; Cytokine-cytokine receptor interaction chemokine activity;; chemotaxis;; cytokine activity;; extracellular region;; extracellular space;; immune response;; inflammatory response extracellular region;; extracellular region part extracellular region part;; extracellular space binding protein binding immune system process;; locomotion;; response to stimulus behavior;; immune response;; response to chemical stimulus;; response to external stimulus;; response to stress;; taxis 179.4111 194.3186 248.1804 104.7680 95.1803 96.5508 0.011682809 1.05593 7.68155 6.62562 1348550 1450018_s_at 14 D2 chr14:76160898-76161380 14 D3 UGA Mm.46067 67554 Slc25a30 Solute carrier family 25, member 30, mRNA (cDNA clone MGC:31367 IMAGE:4238839) binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport;; transporter activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; transporter activity establishment of localization;; localization establishment of localization;; transport 230.7012 204.0335 204.7762 99.9998 93.9055 105.8698 0.00016309978 1.09244 7.73348 6.64105 1340492 1450511_at 4 26.3 cM chr4:58386625-58387120 4 B3 chr4:58298833-58387314 4 B3 RSQ Mm.16148 NM_001037130 5 1 18198 RP23-170A3.1 Musk muscle, skeletal, receptor tyrosine kinase (Musk), transcript variant 5, mRNA. Agrin in Postsynaptic Differentiation;; Role of nicotinic acetylcholine receptors in the regulation of apoptosis ATP binding;; integral to membrane;; integral to plasma membrane;; kinase activity;; membrane;; neuromuscular junction;; neuromuscular junction development;; nucleotide binding;; plasma membrane;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; protein tyrosine kinase activity;; receptor activity;; receptor clustering;; receptor clustering;; regulation of synaptic growth at neuromuscular junction;; regulation of transcription, DNA-dependent;; transferase activity;; transmembrane receptor protein tyrosine kinase activity cell;; cell part;; synapse cell part;; membrane;; membrane part;; neuromuscular junction binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell communication;; cellular component assembly;; cellular developmental process;; cellular macromolecular complex subunit organization;; cellular metabolic process;; developmental growth;; extracellular structure organization;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of cellular component biogenesis;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; synaptogenesis;; system process 358.2277 371.8831 344.6403 101.7634 102.7790 125.7799 0.0016123551 1.70838 8.48413 6.77574 1340635 1450698_at 2 chr2:127163556-127163826 2 F1 chr2:127161894-127164113 2 F1 RSQ Mm.4729 NM_010090 1 1 13537 RP23-206D14.6 Dusp2 dual specificity phosphatase 2 (Dusp2), mRNA. Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] dephosphorylation;; hydrolase activity;; MAP kinase tyrosine/serine/threonine phosphatase activity;; mitogen-activated protein kinase binding;; nucleus;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1411.9536 1425.8560 1435.1444 462.7012 460.5133 568.4920 0.0041427391 1.52535 10.47602 8.95068 1340651 1450716_at 16 53.4 cM chr16:85794592-85794942 16 C3.3 chr16:85794071-85803360 16 C3.3 RSQ Mm.1421 NM_009621 1 1 11504 Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), mRNA. basement membrane;; cytoplasmic vesicle;; extracellular matrix;; extracellular region;; heart trabecula formation;; heparin binding;; hydrolase activity;; kidney development;; metal ion binding;; metalloendopeptidase activity;; metalloendopeptidase activity;; metalloendopeptidase activity;; metallopeptidase activity;; negative regulation of angiogenesis;; ovulation from ovarian follicle;; peptidase activity;; protein binding;; proteinaceous extracellular matrix;; proteolysis;; zinc ion binding cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular matrix;; extracellular matrix part;; extracellular region part;; intracellular;; intracellular organelle;; intracellular part;; vesicle binding;; catalytic activity carbohydrate binding;; hydrolase activity;; ion binding;; pattern binding;; protein binding anatomical structure formation;; biological regulation;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; catabolic process;; gamete generation;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of developmental process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of developmental process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 371.2759 321.0158 342.5746 179.8279 163.5244 157.4904 0.00023550252 1.04672 8.42771 7.38099 1340684 1450759_at 13 A3.3|13 20.0 cM chr13:38591469-38591997 13 A3.3 UG5 Mm.385759 12161 Bmp6 Bone morphogenetic protein 6 (Bmp6), mRNA Hedgehog signaling pathway;; TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; Hedgehog signaling pathway [PATH:mmu04340] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PAT BMP signaling pathway;; cartilage development;; cell differentiation;; cytokine activity;; extracellular region;; extracellular space;; growth;; growth factor activity;; inflammatory response;; multicellular organismal development;; ossification;; osteoblast differentiation;; protein binding extracellular region;; extracellular region part extracellular region part;; extracellular space binding protein binding biological regulation;; cellular process;; developmental process;; growth;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; cell communication;; cellular developmental process;; multicellular organismal development;; ossification;; regulation of biological process;; regulation of cellular process;; response to external stimulus;; response to stress 647.2192 579.5104 701.8720 188.9717 183.5334 181.4054 0.0013118147 1.79562 9.32396 7.52833 1348775 1450826_a_at 7 23.5 cM chr7:53967388-53967984 7 B4 chr7:53967367-53971046 7 B4 RSQ Mm.14277 NM_011315 1 1 20210 Saa3 serum amyloid A 3 (Saa3), mRNA. acute-phase response;; extracellular region;; high-density lipoprotein particle extracellular region;; extracellular region part;; macromolecular complex extracellular region part;; extracellular space;; plasma lipoprotein particle;; protein-lipid complex response to stimulus response to external stimulus;; response to stress 627.2333 643.6571 628.5221 191.6381 211.9297 180.3432 0.0011904982 1.70485 9.30628 7.60143 1348802 1450922_a_at 1 101.5 cM chr1:188448391-188448651 1 H5 chr1:188447064-188529871 1 H5 RSQ Mm.18213 NM_009367 1 1 21808 Tgfb2 transforming growth factor, beta 2 (Tgfb2), mRNA. Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Cytokine-cytokine receptor interaction;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; Renal cell carcinoma;; TGF-beta signaling pathway activation-induced cell death of T cells;; axon;; axon guidance;; blood vessel development;; blood vessel remodeling;; cartilage condensation;; cell growth;; cell proliferation;; cell soma;; dopamine biosynthetic process;; extracellular matrix organization;; extracellular region;; extracellular space;; growth;; growth factor activity;; hair follicle development;; hair follicle morphogenesis;; heart development;; hemopoiesis;; induction of apoptosis;; negative regulation of keratinocyte differentiation;; neuron development;; neuron fate commitment;; pathway-restricted SMAD protein phosphorylation;; positive regulation of cell cycle;; protein binding;; regulation of apoptosis;; skeletal system development;; somatic stem cell division;; transforming growth factor beta receptor binding cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell soma;; extracellular region part;; extracellular space binding protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell division;; cell growth;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; extracellular structure organization;; immune system development;; leukocyte homeostasis;; localization of cell;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; tissue remodeling 301.1696 351.7740 350.3053 129.8592 139.3636 145.2075 0.00035072531 1.27331 8.38180 7.10850 1340805 1450923_at 1 101.5 cM chr1:188447467-188447940 1 H5 chr1:188447064-188529871 1 H5 RSQ Mm.18213 NM_009367 1 1 21808 Tgfb2 transforming growth factor, beta 2 (Tgfb2), mRNA. Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Cytokine-cytokine receptor interaction;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; Renal cell carcinoma;; TGF-beta signaling pathway activation-induced cell death of T cells;; axon;; axon guidance;; blood vessel development;; blood vessel remodeling;; cartilage condensation;; cell growth;; cell proliferation;; cell soma;; dopamine biosynthetic process;; extracellular matrix organization;; extracellular region;; extracellular space;; growth;; growth factor activity;; hair follicle development;; hair follicle morphogenesis;; heart development;; hemopoiesis;; induction of apoptosis;; negative regulation of keratinocyte differentiation;; neuron development;; neuron fate commitment;; pathway-restricted SMAD protein phosphorylation;; positive regulation of cell cycle;; protein binding;; regulation of apoptosis;; skeletal system development;; somatic stem cell division;; transforming growth factor beta receptor binding cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell soma;; extracellular region part;; extracellular space binding protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell division;; cell growth;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; extracellular structure organization;; immune system development;; leukocyte homeostasis;; localization of cell;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; tissue remodeling 1911.5043 1968.7630 1895.6206 490.9640 531.4408 556.4862 0.00029070513 1.87286 10.91067 9.03781 1348818 1451021_a_at 14 chr14:99701186-99702697 14 E2.2 chr14:99697909-99712631 14 E2.2 RSQ Mm.30262 NM_009769 1 1 12224 Klf5 Kruppel-like factor 5 (Klf5), mRNA. angiogenesis;; DNA binding;; DNA binding;; intracellular;; metal ion binding;; microvillus assembly;; nucleic acid binding;; nucleus;; positive regulation of transcription;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell projection organization;; cellular component assembly;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 393.1568 353.1681 302.2436 163.5986 157.8821 172.6896 0.0056803601 1.07799 8.44091 7.36292 1340893 1451027_at 11 chr11:119862181-119862738 11 E2 chr11:119804405-119863932 11 E2 RSQ Mm.197534 NM_130862 2 1 108100 RP23-390H16.1 Baiap2 brain-specific angiogenesis inhibitor 1-associated protein 2 (Baiap2), transcript variant 2, mRNA. Rho cell motility signaling pathway Adherens junction;; Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] cell projection;; cytoplasm;; cytoskeletal adaptor activity;; filopodium assembly;; membrane;; protein binding;; Rho protein signal transduction;; SH3 domain binding;; signal transduction cell;; cell part cell part;; cell projection;; intracellular;; intracellular part;; membrane binding molecular adaptor activity;; protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; regulation of biological process cell communication;; cell projection organization;; cellular component assembly;; regulation of biological process;; regulation of cellular process 519.6935 634.6367 557.1505 213.8036 177.6748 169.2024 0.00032791091 1.61246 9.15108 7.53861 1341119 1451355_at 4 chr4:86566201-86566728 4 C4 chr4:86520367-86566779 4 C4 RSQ Mm.45019 NM_139306 1 1 230379 RP24-468M3.3 Acer2 alkaline ceramidase 2 (Acer2), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramidase activity;; ceramide metabolic process;; endoplasmic reticulum membrane;; Golgi apparatus;; Golgi membrane;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;; integral to membrane;; lipid metabolic process;; membrane cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity hydrolase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 655.1137 677.4130 641.7253 253.7721 341.0802 353.8710 0.017681915 1.07229 9.36177 8.28948 1341207 1451478_at 4 E1 chr4:147869405-147869840 4 E2 UG5 Mm.388929 654812 RP23-423L9.2 Angptl7 Angiopoietin-like 7, mRNA (cDNA clone MGC:32448 IMAGE:5043159) extracellular region;; receptor binding;; signal transduction extracellular region binding protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 322.3589 348.6978 288.6527 136.2647 138.0779 158.1350 0.00043507822 1.14898 8.31718 7.16821 1341279 1451569_at 6 D1 chr6:92118495-92118956 6 D1 UGA Mm.87062 22026 Nr2c2 CD-1 orphan receptor TAK1 (TAK1) DNA binding;; ligand-dependent nuclear receptor activity;; metal ion binding;; nucleus;; receptor activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; spermatocyte division;; spermatogenesis;; spermatogenesis;; steroid hormone receptor activity;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; reproduction;; reproductive process biosynthetic process;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 1414.2219 1398.2630 1416.4771 567.6845 719.8648 603.9091 0.0074764989 1.16820 10.46110 9.29291 1341282 1451577_at 16 B4|16 28.9 cM chr16:43619340-43619721 16 B4 UGA Mm.440824 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 141.2707 149.2577 160.7181 72.0641 71.2836 66.6346 0.00018509136 1.10249 7.23079 6.12830 1348987 1451596_a_at 11 E2 chr11:116397391-116397921 11 E2 UG5 Mm.20944 20698 RP23-193A16.4 Sphk1 Sphingosine kinase 1, mRNA (cDNA clone MGC:47288 IMAGE:4221357) Phospholipids as signalling intermediaries Calcium signaling pathway;; Metabolic pathways;; Sphingolipid metabolism;; VEGF signaling pathway CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600] Environmental Information Processing; Signal Transduction; VEGF signaling pathway [PATH:mmu04370] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; ATP binding;; blood vessel development;; brain development;; calmodulin binding;; cytoplasm;; diacylglycerol kinase activity;; DNA binding;; inflammatory response;; kinase activity;; membrane fraction;; negative regulation of apoptosis;; nucleotide binding;; positive regulation of cell proliferation;; positive regulation of fibroblast proliferation;; regulation of interleukin-1 beta production;; soluble fraction;; sphinganine kinase activity;; sphinganine kinase activity;; transferase activity cell;; cell part cell fraction;; cell part;; intracellular;; intracellular part binding;; catalytic activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; cell communication;; cell death;; cell proliferation;; cellular metabolic process;; cytokine production;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; response to external stimulus;; response to stress 491.4297 469.7440 450.4501 58.3130 60.2290 52.2288 1.5708628e-05 3.04896 8.87727 5.82830 1341305 1451612_at 8 C5|8 45.0 cM chr8:96703143-96703979 8 C5 UGA Mm.192991 17748 Mt1 Metallothionein 1, mRNA (cDNA clone MGC:47147 IMAGE:4990006) cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 1092.1301 1065.3775 1251.1932 600.3029 536.7532 511.1632 0.00046621924 1.04795 10.14639 9.09843 1348997 1451628_a_at 10 38.0 cM chr10:69486782-69487344 10 B5.3 chr10:68996455-69490184 10 B5.3 RSQ Mm.235960 NM_170730 9 1 11735 Ank3 ankyrin 3, epithelial (Ank3), transcript variant 9, mRNA. axon;; axon guidance;; membrane fraction;; protein binding;; protein binding;; synapse;; synapse organization cell;; cell part;; synapse cell fraction;; cell part;; cell projection binding protein binding cellular component organization;; cellular process;; developmental process;; localization;; multicellular organismal process anatomical structure development;; anatomical structure morphogenesis;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; extracellular structure organization;; localization of cell;; multicellular organismal development 403.4822 430.6428 413.8841 137.4298 156.3615 151.3066 0.00019769304 1.48906 8.69993 7.21087 1341319 1451634_at 17 7.36 cM chr17:13007636-13008080 17 A1 chr17:12934176-13008423 17 A1 RSQ NR_002853 2 1 104103 Airn antisense Igf2r RNA (Airn), transcript variant 1, non-coding RNA. genetic imprinting biological regulation;; cellular process;; metabolic process;; regulation of biological process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of metabolic process 4180.2906 4203.4998 4195.7075 582.9237 744.5343 839.1176 0.0036417059 2.55379 12.03382 9.48003 1341347 1451680_at 2 chr2:151935283-151935614 2 G3 chr2:151931465-151937089 2 G3 RSQ Mm.218639 NM_029688 1 1 76650 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA. antioxidant activity;; ATP binding;; cytoplasm;; cytosol;; magnesium ion binding;; nucleotide binding;; oxidation reduction;; oxidoreductase activity;; response to oxidative stress;; sulfiredoxin activity cell;; cell part cell part;; intracellular;; intracellular part antioxidant activity;; binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity metabolic process;; response to stimulus oxidation reduction;; response to chemical stimulus;; response to stress 351.4852 390.0426 342.2789 129.3800 117.5628 98.9141 0.0010369686 1.65433 8.49461 6.84029 1341364 1451715_at 2 91.0 cM chr2:160191130-160191719 2 H2 chr2:160189412-160192801 2 H2 RSQ Mm.330745 NM_010658 1 1 16658 RP23-333A18.1 Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA. brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 715.7394 690.2579 665.3594 341.1308 278.8834 265.8186 0.0050867127 1.23342 9.43076 8.19733 1341365 1451716_at 2 H2|2 91.0 cM chr2:160189869-160190403 2 H2 UG5 Mm.330745 16658 RP23-333A18.1 Mafb V-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 103.5565 98.2182 107.1181 35.5372 41.6785 56.1464 0.020552496 1.23721 6.68508 5.44787 1341382 1451739_at 14 E2.2 chr14:99704096-99704548 14 E2.2 UGA Mm.30262 12224 Klf5 Kruppel-like factor 5, mRNA (cDNA clone MGC:13705 IMAGE:4208633) angiogenesis;; DNA binding;; DNA binding;; intracellular;; metal ion binding;; microvillus assembly;; nucleic acid binding;; nucleus;; positive regulation of transcription;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell projection organization;; cellular component assembly;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1322.7983 1261.2579 1256.2077 474.1454 547.1144 481.6064 0.00080735403 1.35610 10.32163 8.96553 1341390 1451756_at 5 G|5 82.0 cM chr5:148449686-148450062 5 G3 UGA Mm.389712 14254 Flt1 FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) Cytokine-cytokine receptor interaction;; Endocytosis;; Focal adhesion CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] angiogenesis;; ATP binding;; cell differentiation;; cell migration;; identical protein binding;; integral to membrane;; kinase activity;; membrane;; multicellular organismal development;; nucleotide binding;; patterning of blood vessels;; protein amino acid phosphorylation;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway;; vascular endothelial growth factor receptor activity;; vascular endothelial growth factor receptor signaling pathway;; vascular endothelial growth factor receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 919.1697 1070.3384 963.5013 385.9763 437.5392 407.5932 0.00014834265 1.26119 9.94006 8.67887 1349134 1451932_a_at F2 chr3:95480329-95480688 3 F2.1 chr3:95480126-95491781 3 F2.1 RSQ Mm.475756 NM_144899 1 1 229595 Adamtsl4 ADAMTS-like 4 (Adamtsl4), mRNA. apoptosis;; extracellular matrix;; extracellular matrix organization;; extracellular region;; interstitial matrix;; metalloendopeptidase activity;; peptidase activity extracellular region;; extracellular region part extracellular matrix;; extracellular region part catalytic activity hydrolase activity cellular component organization;; cellular process;; death cell death;; extracellular structure organization 478.4582 483.1948 490.7465 255.4788 254.9805 171.7513 0.027697751 1.11402 8.91918 7.80516 1341673 1452209_at 2 chr2:59192689-59193222 2 C1.1 chr2:58998906-59193262 2 C1.1 RSQ Mm.260938 NM_175464 2 1 227937 RP23-311G5.1 Pkp4 plakophilin 4 (Pkp4), transcript variant 2, mRNA. binding;; cell adhesion;; cell junction;; protein binding cell;; cell part cell part;; membrane;; membrane part binding protein binding biological adhesion;; cellular process cell adhesion 313.2149 289.4501 322.5842 147.3440 132.1754 85.1842 0.025783706 1.37995 8.26724 6.88729 1349241 1452348_s_at 1 chr1:175829524-175831822 1 H3 chr1:175826485-175843053 1 H3 RSQ Mm.476726 NM_001033450 3 3 381308 Mnda myeloid cell nuclear differentiation antigen (Mnda), mRNA. 1043.0394 1148.4852 991.3447 348.7193 321.1248 262.9268 0.0009837498 1.77797 10.04845 8.27048 1349242 1452349_x_at 1 chr1:175826485-175843053 1 H3 RSQ Mm.476726 NM_001033450 2 2 381308 Mnda myeloid cell nuclear differentiation antigen (Mnda), mRNA. 390.8001 356.5885 335.1519 144.0691 213.9596 168.7820 0.014303124 1.05542 8.49236 7.43694 1341817 1452378_at 19A chr19:5800663-5801120 19 A chr19:5795689-5802671 19 A RSQ NR_002847 1 1 72289 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA. 1541.3642 1547.7487 1611.6091 452.2785 592.9019 585.0964 0.0057368039 1.53833 10.61341 9.07508 1341848 1452418_at 1 chr1:9226200-9228974 1 A2 RSQ XM_001472850 5 3 100039464 LOC100039464 PREDICTED: similar to gag protein, transcript variant 1 (LOC100039464), mRNA. 1834.0718 1724.7099 1810.0079 811.2314 802.9826 720.1530 0.00034808289 1.20313 10.80492 9.60178 1341885 1452478_at 18 E1 chr18:65425204-65425576 18 E1 UGA Mm.296528 225638 Alpk2 Heart alpha-kinase ATP binding;; kinase activity;; protein amino acid phosphorylation;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1353.7991 1394.0735 1320.7487 419.4297 461.6294 445.5274 3.5912455e-05 1.61759 10.40501 8.78742 1349296 1452519_a_at 7 10.2 cM chr7:29161986-29162456 7 A3 chr7:29161802-29164247 7 A3 RSQ Mm.389856 NM_011756 1 1 22695 Zfp36 zinc finger protein 36 (Zfp36), mRNA. AU-rich element binding;; cytoplasm;; cytosol;; cytosol;; DNA binding;; metal ion binding;; mRNA binding;; mRNA binding;; mRNA catabolic process;; negative regulation of inflammatory response;; negative regulation of myeloid cell differentiation;; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;; nuclear-transcribed mRNA poly(A) tail shortening;; nucleic acid binding;; nucleus;; protein kinase cascade;; regulation of mRNA stability;; RNA destabilization;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of response to stimulus;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; response to external stimulus;; response to stress 1570.6307 1570.7863 1552.2630 454.0406 690.8022 420.7867 0.018281371 1.61960 10.61152 8.99192 1349404 1453238_s_at 11 chr11:86626266-86629631 11 C RSQ NR_002860 11 10 319269 A130040M12Rik RIKEN cDNA A130040M12 gene (A130040M12Rik), non-coding RNA. 691.2556 688.4005 653.6500 243.5964 334.8340 282.7025 0.009011346 1.25125 9.40418 8.15293 1342147 1453287_at 15 chr15:31254076-31254667 15 B2 chr15:31253711-31297309 15 B2 RSQ Mm.102470 NM_026153 1 1 67434 Ankrd33b ankyrin repeat domain 33B (Ankrd33b), transcript variant 1, mRNA. DNA binding binding nucleic acid binding 3904.7439 3913.8397 3797.7209 1797.2138 2240.4972 1552.8081 0.019278066 1.07150 11.91877 10.84727 1349428 1453473_a_at 17 3.1 cM chr17:6429259-6435444 17 A1 RSQ Mm.1948 NM_009342 14 6 21648 Dynlt1 dynein light chain Tctex-type 1 (Dynlt1), mRNA. axonemal dynein complex;; cytoplasmic dynein complex;; cytoplasmic dynein complex;; dynein complex;; Golgi apparatus;; microtubule;; microtubule-based process;; motor activity;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part axoneme;; axoneme part;; cell part;; cell projection;; cell projection part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity hydrolase activity;; protein binding cellular process microtubule-based process 1946.8686 1970.2910 1969.7860 884.3114 570.5846 532.9160 0.019706689 1.60416 10.93832 9.33416 1349481 1453851_a_at 13 chr13:51943246-51943781 13 A5 chr13:51942063-51943844 13 A5 RSQ Mm.281298 NM_011817 1 1 23882 Gadd45g growth arrest and DNA-damage-inducible 45 gamma (Gadd45g), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; interferon-gamma biosynthetic process;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; T-helper 1 cell differentiation cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; cytokine production;; immune response;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 240.0356 270.2989 260.0346 115.6685 125.8989 100.4656 0.0015282704 1.17585 8.00269 6.82684 1349517 1454037_a_at 5 82.0 cM chr5:148466686-148485183 5 G3 chr5:148373771-148537564 5 G3 RSQ Mm.389712 NM_010228 1 1 14254 Flt1 FMS-like tyrosine kinase 1 (Flt1), mRNA. Cytokine-cytokine receptor interaction;; Endocytosis;; Focal adhesion CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] angiogenesis;; ATP binding;; cell differentiation;; cell migration;; identical protein binding;; integral to membrane;; kinase activity;; membrane;; multicellular organismal development;; nucleotide binding;; patterning of blood vessels;; protein amino acid phosphorylation;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway;; vascular endothelial growth factor receptor activity;; vascular endothelial growth factor receptor signaling pathway;; vascular endothelial growth factor receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 589.3261 566.1156 527.2449 307.0480 306.9603 223.2480 0.015274878 1.02116 9.13007 8.10891 1349753 1455826_a_at 9 chr9:45670188-45670276 9 A5.2 chr9:45646611-45670567 9 A5.2 RSQ Mm.24044 NM_001145947 2 1 23821 Bace1 beta-site APP cleaving enzyme 1 (Bace1), transcript variant 2, mRNA. Generation of amyloid b-peptide by PS1 Alzheimer's disease CLASS Human Diseases; Neurodegenerative Diseases; Alzheimer's disease [PATH:mmu05010] aspartic-type endopeptidase activity;; axon;; cytoplasmic vesicle;; endopeptidase activity;; hydrolase activity;; integral to membrane;; membrane;; membrane fraction;; peptidase activity;; proteolysis cell;; cell part;; organelle cell fraction;; cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; vesicle catalytic activity hydrolase activity metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 3532.9631 3291.2873 3378.5646 380.5947 288.2147 403.0422 0.0014827499 3.26513 11.73110 8.46597 1349775 1455899_x_at 11 chr11:117827463-117827587 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 763.4848 831.3570 798.5396 355.6544 325.9099 306.1279 0.00028478051 1.27878 9.63900 8.36022 1349776 1455900_x_at 2 89.0 cM chr2:157942148-157942327 2 H1 IPA Tgm2 transglutaminase 2, C polypeptide 2547.2819 2516.3176 2565.6128 288.0805 200.8621 249.8199 0.001942104 3.38393 11.31231 7.92838 1349871 1456212_x_at 11 E2 chr11:117827490-117827770 11 E2 IPA Mm.3468 Socs3 Suppressor of cytokine signaling 3 (Socs3), mRNA 208.0730 213.4019 206.8505 68.1122 71.9474 92.0111 0.0078513257 1.44946 7.71027 6.26082 1342688 1457147_at 2 A3 chr2:20724458-20725017 2 A3 UGA Mm.237935 208618 RP23-436G18.1 Etl4 Enhancer trap locus 4, mRNA (cDNA clone IMAGE:4988846) cytoplasm;; embryonic skeletal system development;; multicellular organismal development cell;; cell part cell part;; intracellular;; intracellular part developmental process;; multicellular organismal process anatomical structure development;; embryonic development;; multicellular organismal development 198.4157 171.6622 146.4321 85.3619 82.4758 77.7347 0.008884976 1.06266 7.41663 6.35397 1342840 1460227_at X 6.2 cM chrX:20449919-20451746 X A1.3 chrX:20447291-20451863 X A1.3 RSQ Mm.8245 NM_011593 2 1 21857 RP23-132C19.3 Timp1 tissue inhibitor of metalloproteinase 1 (Timp1), transcript variant 2, mRNA. Inhibition of Matrix Metalloproteinases basement membrane;; enzyme inhibitor activity;; erythrocyte maturation;; extracellular region;; metalloendopeptidase inhibitor activity;; proteinaceous extracellular matrix extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part enzyme regulator activity enzyme inhibitor activity;; metalloenzyme regulator activity biological regulation;; cellular process;; developmental process;; immune system process;; multicellular organismal process anatomical structure development;; cellular developmental process;; developmental maturation;; immune system development;; multicellular organismal development;; regulation of biological quality 169.3280 186.2567 185.7142 40.9233 51.9237 33.3449 0.0052350661 2.12307 7.49392 5.37085 1342983 1460417_at 6 chr6:31115507-31168433 6 A3.3 RSQ XR_035177 2 1 232685 AB041803 PREDICTED: cDNA sequence AB041803 (AB041803), misc RNA. 809.1483 836.9576 830.6730 349.4893 375.8326 486.0467 0.017664352 1.04647 9.68914 8.64267 1342988 1460426_at 3 F2.2|3 51.5 cM chr3:97550660-97557001 3 F2.2 UGA Mm.129840 83679 Pde4dip Phosphodiesterase 4D interacting protein (myomegalin), mRNA (cDNA clone IMAGE:4954590) cytoplasm;; Golgi apparatus;; nucleus;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding 249.1946 279.8767 280.6690 83.2745 69.1519 74.9461 8.5178578e-05 1.83441 8.07417 6.23976 1343058 1460670_at 18 3.0 cM chr18:12314622-12314869 18 A1 chr18:12287358-12315876 18 A1 RSQ Mm.28551 NM_024182 1 1 66878 Riok3 RIO kinase 3 (yeast) (Riok3), mRNA. ATP binding;; catalytic activity;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 440.7553 451.3074 438.1184 122.2080 189.0929 209.3232 0.027798395 1.39041 8.79233 7.40191 1370792 1420098_s_at 13 chr13:44852332-44852589 13 A5 UGA Mm.395784 Transcribed locus 157.4279 160.8017 171.8950 37.5507 31.6839 29.9369 0.00051526038 2.31092 7.35102 5.04010 1370809 1420312_s_at IPA Unknown 721.2315 703.3000 714.5902 243.2002 335.2188 213.8707 0.016776483 1.45924 9.47776 8.01852 1350443 1428352_at 8 chr8:73359362-73359595 8 B3.3 chr8:73359036-73363619 8 B3.3 RSQ Mm.24215 NM_027560 1 1 70807 Arrdc2 arrestin domain containing 2 (Arrdc2), mRNA. 149.7921 171.9226 159.7830 22.1049 22.4992 14.7266 0.0024061758 3.04465 7.32413 4.27948 1350626 1428663_at 3 chr3:131021980-131022466 3 G3 chr3:131021902-131047841 3 G3 RSQ Mm.273360 NM_028943 1 1 74442 Sgms2 sphingomyelin synthase 2 (Sgms2), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide cholinephosphotransferase activity;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; integral to plasma membrane;; kinase activity;; lipid metabolic process;; membrane;; plasma membrane;; sphingolipid metabolic process;; sphingomyelin biosynthetic process;; sphingomyelin synthase activity;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; organophosphate metabolic process;; primary metabolic process 446.6242 435.1519 418.9619 170.0964 167.5998 173.0215 2.971282e-05 1.34836 8.75966 7.41130 1350820 1428976_at 10 49.0 cM chr10:90623328-90623756 10 C2 chr10:90623161-90634327 10 C2 RSQ Mm.159684 NM_011605 1 1 21917 Tmpo thymopoietin (Tmpo), transcript variant 1, mRNA. chromatin;; chromosome;; DNA binding;; integral to membrane;; membrane;; nuclear envelope;; nucleus;; protein binding;; protein binding;; regulation of transcription cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle envelope;; organelle part binding nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 176.0733 163.8612 185.4764 56.7982 66.7099 85.5941 0.010701632 1.34814 7.45048 6.10235 1350856 1429029_at 3 G3 chr3:131025716-131026224 3 G3 UGA Mm.273360 74442 Sgms2 Sphingomyelin synthase 2 (Sgms2), mRNA Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide cholinephosphotransferase activity;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; integral to plasma membrane;; kinase activity;; lipid metabolic process;; membrane;; plasma membrane;; sphingolipid metabolic process;; sphingomyelin biosynthetic process;; sphingomyelin synthase activity;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; organophosphate metabolic process;; primary metabolic process 449.9078 429.0964 416.2630 218.1116 210.2545 200.4126 2.8193052e-05 1.04275 8.75333 7.71058 1350997 1429236_at 14 B chr14:32872910-32873143 14 B UGA Mm.40681 78754 Galntl2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2, mRNA (cDNA clone MGC:161357 IMAGE:40143107) Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; O-Glycan biosynthesis [PATH:mmu00512];; O-Glycan biosynthesis calcium ion binding;; Golgi apparatus;; integral to membrane;; manganese ion binding;; membrane;; polypeptide N-acetylgalactosaminyltransferase activity;; sugar binding;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity carbohydrate binding;; ion binding;; transferase activity 2651.2744 2589.4455 2539.6318 1115.3331 1108.1391 1272.8304 0.00177508 1.15676 11.34043 10.18367 1351041 1429300_at 12 chr12:112214932-112215222 12 F1 chr12:112213562-112217231 12 F1 RSQ Mm.250989 NM_175207 1 1 74251 Ankrd9 ankyrin repeat domain 9 (Ankrd9), mRNA. hydrolase activity catalytic activity hydrolase activity 490.1945 545.4885 531.4098 189.8447 211.8299 242.2117 0.0019181976 1.28891 9.02743 7.73852 1351042 1429304_at 8 A1.1 chr8:11614351-11614743 8 A1.1 UGA Mm.12459 102334 Ankrd10 Ankyrin repeat domain 10 (Ankrd10), mRNA 770.8939 816.5641 783.4769 331.2824 460.8672 368.0517 0.01534984 1.04456 9.62585 8.58130 1351133 1429433_at 1 chr1:164650697-164670489 1 H2.1 chr1:164601915-164670687 1 H2.1 RSQ Mm.245446 NM_001081290 1 1 226562 Bat2d BAT2 domain containing 1 (Bat2d), mRNA. 1520.5557 1413.4250 1449.4810 629.6930 736.0449 707.3292 0.00099945353 1.08276 10.51223 9.42946 1351240 1429593_at 15 chr15:96528309-96529220 15 F1 chr15:96517822-96530129 15 F1 RSQ Mm.46754 NM_175121 1 1 67760 Slc38a2 solute carrier family 38, member 2 (Slc38a2), mRNA. amino acid transmembrane transporter activity;; amino acid transport;; integral to membrane;; ion transport;; membrane;; plasma membrane;; sodium ion binding;; sodium ion transport;; symporter activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 213.7861 194.7983 208.1551 89.1978 118.5466 92.5447 0.0095894959 1.04902 7.68246 6.63344 1351285 1429653_at 8 chr8:123102647-123103192 8 E1 chr8:123059756-123105283 8 E1 RSQ Mm.334856 NM_001145897 3 1 382034 Gse1 genetic suppressor element 1 (Gse1), transcript variant 3, mRNA. 350.0629 369.2184 348.2867 147.6102 135.4853 103.3945 0.0091245899 1.48143 8.47464 6.99322 1351449 1429870_at 3 A3 chr3:28259219-28259607 3 A3 UG5 Mm.126193 665113 Tnik TRAF2 and NCK interacting kinase, mRNA (cDNA clone MGC:183916 IMAGE:9087916) ATP binding;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; small GTPase regulator activity;; transferase activity binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleoside-triphosphatase regulator activity;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1515.4177 1480.7350 1444.3174 491.5905 604.3024 492.1917 0.0032792488 1.49008 10.53126 9.04117 1351474 1429900_at 6 chr6:31058893-31059397 6 A3.3 UGA Mm.109877 Transcribed locus 155.1161 135.5725 143.1183 51.7500 69.4427 65.1060 0.0044366395 1.22841 7.17373 5.94532 1351702 1430183_at 1 chr1:170349828-170350347 1 H2.3 UGA Mm.441506 Transcribed locus 163.3294 172.5743 179.3186 58.2947 53.2984 30.0474 0.021963542 1.91954 7.42303 5.50349 1351838 1430352_at 6 D1 chr6:92795416-92795850 6 D1 UGA Mm.257557 101401 mCG_142056 Adamts9 MKIAA1312 protein endopeptidase activity;; extracellular space;; metallopeptidase activity;; positive regulation of melanocyte differentiation;; proteinaceous extracellular matrix;; proteolysis;; proteolysis;; regulation of pigmentation during development extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; pigmentation;; positive regulation of biological process;; regulation of biological process catabolic process;; cellular developmental process;; macromolecule metabolic process;; pigmentation during development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 146.5877 150.8532 147.7075 39.4089 51.0285 47.2845 0.0038343952 1.70075 7.21307 5.51233 1351845 1430362_at chr19:40547310-40547726 19 C3 IPA 5730409N24Rik RIKEN cDNA 5730409N24 gene 37.6487 47.3004 35.4280 16.2362 19.5770 21.6505 0.0037629812 1.06552 5.31504 4.24952 1351852 1430370_at 1 H4-H6 chr1:187233494-187233858 1 H5 UGA Mm.154511 107508 Eprs Glutamyl-prolyl-tRNA synthetase, mRNA (cDNA clone IMAGE:3482737) Aminoacyl-tRNA biosynthesis;; Metabolic pathways CLASS Metabolism; Metabolism of Cofactors and Vitamins; Porphyrin and chlorophyll metabolism [PATH:mmu00860] Genetic Information Processing; Translation; Aminoacyl-tRNA biosynthesis [PATH:mmu00970];; Porphyrin and chlorophyll metabolism aminoacyl-tRNA ligase activity;; ATP binding;; catalytic activity;; cytoplasm;; glutamate-tRNA ligase activity;; glutamyl-tRNA aminoacylation;; ligase activity;; nucleotide binding;; proline-tRNA ligase activity;; prolyl-tRNA aminoacylation;; RNA binding;; translation;; tRNA aminoacylation for protein translation cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ligase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 115.4007 100.5551 96.9803 49.7839 51.6039 45.2680 0.00051389157 1.09151 6.70066 5.60915 1352062 1430646_at 14 chr14:120800227-120800737 14 E4 IPA 5830407P18Rik RIKEN cDNA 5830407P18 gene 383.6388 365.6560 313.3908 95.4936 103.2550 91.5338 0.00023444939 1.86871 8.46326 6.59454 1352101 1430702_at 15 chr15:98590670-98590993 15 F1 chr15:98590568-98592483 15 F1 RSQ Mm.441883 NM_175232 1 1 76061 5830427D03Rik RIKEN cDNA 5830427D03 gene (5830427D03Rik), mRNA. 9433.1238 9259.4961 9238.1963 3934.7630 4022.8224 4599.7075 0.0032049 1.15675 13.18454 12.02779 1352351 1431043_at 9 F4 chr9:121689700-121692543 9 F4 UG5 Mm.45734 72330 Kbtbd5 Kelch repeat and BTB (POZ) domain containing 5, mRNA (cDNA clone MGC:169513 IMAGE:8860908) protein binding binding protein binding 81.3256 82.4758 80.4278 29.3253 36.5566 41.7785 0.014765997 1.19678 6.34705 5.15027 1353415 1432665_at chr13:110437515-110438024 13 D2.2 IPA 2210416J07Rik RIKEN cDNA 2210416J07 gene 366.4738 387.5431 410.2278 148.2475 159.4852 198.2542 0.0053616448 1.21190 8.59869 7.38678 1353535 1432787_at 5 chr5:15476262-15476595 5 A2 UGA Mm.446079 Transcribed locus 263.0060 299.3766 284.2593 100.4218 128.4346 98.1071 0.002965989 1.38158 8.13861 6.75703 1353584 1432850_at 15 chr15:36181152-36181511 15 B3.1 UGA Mm.440854 Transcribed locus 1834.2010 1780.4161 1640.9575 189.6256 260.8673 176.7876 0.0017335498 3.08640 10.77309 7.68669 1353873 1433148_at chr7:137797332-137797814 7 F3 IPA 4930513N20Rik RIKEN cDNA 4930513N20 gene 117.0374 95.5320 101.9767 37.9231 56.9618 65.5576 0.038833124 1.00307 6.70694 5.70387 1353929 1433207_at IPA 5033430J17Rik RIKEN cDNA 5033430J17 gene 2908.2019 2883.9926 3032.4237 885.3391 1122.8809 694.1395 0.0122713 1.73462 11.52201 9.78739 1354215 1433634_at 8 chr8:129114739-129115115 8 E2 chr8:129112193-129117336 8 E2 RSQ Mm.334918 XM_284454 2 1 270110 Irf2bp2 PREDICTED: interferon regulatory factor 2 binding protein 2, transcript variant 1 (Irf2bp2), mRNA. negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 222.2389 264.1762 259.0106 125.0574 94.8466 100.3231 0.0020691697 1.22524 7.95273 6.72749 1354351 1433898_at 14 chr14:76160237-76160494 14 D3 UGA Mm.396080 Transcribed locus 709.6888 752.1101 749.1160 276.9297 255.5127 261.6229 7.8144053e-06 1.47764 9.52496 8.04732 1354463 1434106_at 9 chr9:111179458-111179967 9 F3 chr9:111174348-111181597 9 F3 RSQ Mm.209005 NM_175266 1 1 77781 Epm2aip1 EPM2A (laforin) interacting protein 1 (Epm2aip1), mRNA. endoplasmic reticulum cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 895.9289 968.5798 964.6927 395.7955 398.8186 367.5773 1.6576166e-05 1.28360 9.88030 8.59670 1354476 1434140_at 8 A2 chr8:13020121-13020475 8 A1.1 UG5 Mm.334413 17207 Mcf2l Guanine nucleotide exchange factor OSTIII mRNA, complete cds, alternatively spliced cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; lamellipodium;; membrane;; phosphatidylinositol binding;; plasma membrane;; protein binding;; regulation of Rho protein signal transduction;; Rho guanyl-nucleotide exchange factor activity;; Rho protein signal transduction cell;; cell part cell leading edge;; cell part;; cell projection;; intracellular;; intracellular part;; membrane binding;; enzyme regulator activity lipid binding;; nucleoside-triphosphatase regulator activity;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 700.8431 719.2352 784.4297 75.8925 102.0345 93.8107 0.00050422278 3.02943 9.51959 6.49016 1371171 1434202_a_at 14 A1 chr14:9128859-9128932 14 A1 UGA Mm.256058 268709 Fam107a Family with sequence similarity 107, member A (Fam107a), mRNA 377.5711 361.0213 337.8389 83.9730 105.8040 97.9957 0.0005297996 1.90833 8.48558 6.57725 1354513 1434203_at 14 chr14:9128829-9129307 14 A1 chr14:9128791-9142290 14 A1 RSQ Mm.256058 NM_183187 1 1 268709 Fam107a family with sequence similarity 107, member A (Fam107a), mRNA. 477.1519 439.0444 383.4660 192.9852 228.1720 227.8985 0.0013016765 1.00030 8.75316 7.75286 1354583 1434350_at 9 chr9:119880327-119880851 9 F4 chr9:119880283-119893776 9 F4 RSQ Mm.477982 NM_153287 1 1 215418 Csrnp1 cysteine-serine-rich nuclear protein 1 (Csrnp1), mRNA. apoptosis;; DNA binding;; face morphogenesis;; nucleus;; palate development;; platelet-derived growth factor receptor signaling pathway;; positive regulation of transcription from RNA polymerase II promoter;; post-embryonic development;; regulation of transcription, DNA-dependent;; skeletal system morphogenesis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell death;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; post-embryonic development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 207.4297 208.1106 207.4490 100.4872 83.4510 72.2200 0.011138922 1.29541 7.69810 6.40268 1354998 1435125_at 12 chr12:104432850-104433264 12 E UG5 Mm.427936 Transcribed locus 159.3496 156.2344 176.4121 84.6464 71.9656 68.1550 0.0013933987 1.13435 7.35548 6.22112 1355059 1435229_at 9 B chr9:40100858-40101373 9 A5.1 UGA Mm.138434 235283 Gramd1b GRAM domain containing 1B, mRNA (cDNA clone MGC:99432 IMAGE:30616509) integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 372.2521 352.9941 376.7788 191.8741 166.4852 168.4244 0.0010463113 1.06733 8.52040 7.45307 1355200 1435459_at 1 chr1:164804683-164805007 1 H2.1 UGA Mm.458151 Transcribed locus 150.3186 157.9297 173.0408 16.3376 17.4830 15.7107 3.379342e-06 3.27943 7.32333 4.04389 1355275 1435579_at 4 UG5 Mm.427140 Transcribed locus 122.4483 102.1966 116.8127 55.8059 49.3603 55.0942 0.00058009394 1.08928 6.82643 5.73715 1355354 1435694_at 18 chr18:39535346-39535896 18 B3 chr18:39152798-39535939 18 B3 RSQ Mm.329396 NM_175164 1 1 71302 Arhgap26 Rho GTPase activating protein 26 (Arhgap26), mRNA. cell junction;; cytoplasm;; cytoskeleton;; GTPase activator activity;; intracellular;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle enzyme regulator activity enzyme activator activity;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 61.6073 49.9463 46.7772 16.9342 18.8200 21.6851 0.000847205 1.46012 5.71169 4.25157 1355485 1435918_at 14 A1 chr14:9130098-9130562 14 A1 UG5 Mm.256058 268709 Fam107a Family with sequence similarity 107, member A (Fam107a), mRNA 190.8741 164.4699 176.2763 56.0655 53.6770 63.5241 8.5159425e-05 1.61845 7.46662 5.84817 1355677 1436200_at X A2 chrX:33906277-33906788 X A3.3 UGA Mm.327654 74365 RP23-145O4.1 Lonrf3 LON peptidase N-terminal domain and ring finger 3, mRNA (cDNA clone MGC:155927 IMAGE:40129613) ATP-dependent peptidase activity;; binding;; metal ion binding;; protein binding;; proteolysis;; zinc ion binding binding;; catalytic activity hydrolase activity;; ion binding;; protein binding metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 799.1938 780.8251 746.5896 333.4076 321.1290 341.3507 6.6830051e-06 1.22406 9.59848 8.37442 1355678 1436202_at 19A chr19:5795727-5796151 19 A chr19:5795689-5802671 19 A RSQ NR_002847 1 1 72289 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA. 883.2305 907.7333 907.8808 389.6821 464.1718 405.9100 0.0038448663 1.10315 9.81304 8.70990 1355793 1436387_at 13 chr13:94129930-94130365 13 C3 UGA Mm.443111 Transcribed locus 153.1169 163.4870 160.2423 65.6854 53.3364 51.2932 0.0035887306 1.49346 7.31188 5.81841 1356093 1436913_at 3 chr3:115975515-115976043 3 G1 chr3:115975470-116126950 3 G1 RSQ Mm.17647 NM_001080818 1 1 229776 Cdc14a CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), mRNA. Cell cycle CLASS Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] cell cycle;; cell division;; dephosphorylation;; hydrolase activity;; nucleus;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity cellular process;; metabolic process cell cycle;; cell division;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 926.8725 1032.5292 943.0098 432.0746 493.8186 454.5984 0.00015223645 1.07263 9.91644 8.84381 1356153 1437065_at 16 B4|16 28.9 cM chr16:43637509-43638069 16 B4 UGA Mm.136238 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone IMAGE:6484816) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 471.4836 454.9973 431.8068 200.8808 177.3062 180.2973 0.00013052401 1.28350 8.82167 7.53818 1371306 1437073_x_at 14 chr14:76159946-76160160 14 D3 UGA Mm.396080 Transcribed locus 338.4798 390.2439 380.8212 110.4357 104.9347 136.2076 0.00088642324 1.66468 8.52804 6.86336 1356231 1437199_at 19 D2 chr19:53615956-53616474 19 D2 UGA Mm.52043 240672 Dusp5 Dual specificity phosphatase 5 (Dusp5), mRNA MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] hydrolase activity;; MAP kinase tyrosine/serine/threonine phosphatase activity catalytic activity hydrolase activity 231.0754 242.5964 270.8637 95.4002 95.9302 114.5361 0.00041733377 1.28552 7.95202 6.66650 1356243 1437219_at 7 chr7:75169335-75169849 7 D1 UGA Mm.436787 Transcribed locus 456.9299 401.8184 460.9338 193.3496 197.5964 170.2855 0.00018573031 1.23378 8.77821 7.54443 1356245 1437224_at 11 chr11:29606699-29607240 11 A3.3 chr11:29593773-29642916 11 A3.3 RSQ Mm.192580 NM_194051 2 1 68585 RP23-176O5.4 Rtn4 reticulon 4 (Rtn4), transcript variant 5, mRNA. angiogenesis;; cell projection;; cell soma;; endoplasmic reticulum;; integral to endoplasmic reticulum membrane;; integral to membrane;; membrane;; negative regulation of anti-apoptosis;; negative regulation of axon extension;; nervous system development;; nuclear envelope;; regulation of cell migration cell;; cell part;; envelope;; organelle;; organelle part cell part;; cell projection;; cell soma;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part anatomical structure formation;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; localization;; locomotion;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell death;; cell motility;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; localization of cell;; multicellular organismal development;; negative regulation of anti-apoptosis;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of developmental process;; regulation of anti-apoptosis;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of localization;; regulation of locomotion;; regulation of multicellular organismal process 241.9925 280.4297 252.9257 92.3813 79.5893 110.4748 0.0029925385 1.46709 8.01096 6.54387 1356345 1437410_at 5 F-G1 chr5:122021168-122021702 5 F UGA Mm.284446 11669 Aldh2 Aldehyde dehydrogenase 2, mitochondrial, mRNA (cDNA clone MGC:6764 IMAGE:3600875) 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation aldehyde dehydrogenase (NAD) activity;; metabolic process;; mitochondrion;; oxidation reduction;; oxidoreductase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity oxidoreductase activity metabolic process oxidation reduction 248.5012 240.5821 210.3925 78.8521 58.7368 90.1229 0.0058168562 1.63778 7.86148 6.22370 1356390 1437493_at 2 chr2:52728790-52729240 2 C1.1 UG5 Mm.274277 Transcribed locus 146.8320 146.7885 157.9181 46.0129 36.5453 47.5652 0.002412252 1.80375 7.23288 5.42914 1356438 1437584_at 17 chr17:47656286-47656414 17 C UGA Mm.453308 Transcribed locus 178.3563 174.5084 177.8324 68.6307 86.1956 82.4230 0.0069038462 1.16828 7.46672 6.29843 1356463 1437638_at 17 chr17:23950981-23951487 17 A3.3 UGA Mm.436876 Transcribed locus, strongly similar to NP_780438.2 serine/arginine repetitive matrix 2 [Mus musculus] 108.4330 121.6541 108.5970 44.1927 41.3511 42.8751 0.00020678594 1.39750 6.81671 5.41922 1356486 1437676_at 11 C chr11:93911380-93911961 11 D UG5 Mm.260737 70834 RP23-378I13.3 Spag9 JNK-associated leucine-zipper protein activation of MAPK activity;; cytoplasm;; JUN kinase binding;; kinesin binding;; protein homooligomerization cell;; cell part cell part;; intracellular;; intracellular part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular component assembly;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 262.5829 273.7075 312.6099 135.7866 130.2255 137.5409 0.0026197013 1.06919 8.14045 7.07126 1356494 1437700_at 3 E2 chr3:68401496-68402039 3 E1 UG5 Mm.331064 30953 Schip1 Schwannomin interacting protein 1 (Schip1), transcript variant 4, mRNA cytoplasm;; face morphogenesis;; fibroblast migration;; kidney development;; nitrogen compound metabolic process;; palate development;; platelet-derived growth factor receptor signaling pathway;; post-embryonic development;; protein binding;; protein homodimerization activity;; skeletal system morphogenesis;; smooth muscle tissue development cell;; cell part cell part;; intracellular;; intracellular part binding protein binding biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; localization of cell;; multicellular organismal development;; nitrogen compound metabolic process;; post-embryonic development;; regulation of biological process;; regulation of cellular process 684.1270 783.3072 721.2501 310.2089 313.9490 367.9784 0.00052102611 1.14365 9.50864 8.36499 1356511 1437745_at 4 1.0 cM chr4:8679995-8712728 4 A1 chr4:8618067-8793957 4 A1 RSQ Mm.138792 NM_001081417 1 1 320790 RP23-464N23.1 Chd7 chromodomain helicase DNA binding protein 7 (Chd7), mRNA. adult heart development;; adult walking behavior;; ATP binding;; ATP-dependent helicase activity;; blood circulation;; blood vessel development;; camera-type eye development;; chromatin;; chromatin assembly or disassembly;; chromatin binding;; chromatin modification;; DNA binding;; ear morphogenesis;; embryonic hindlimb morphogenesis;; female genitalia development;; heart morphogenesis;; helicase activity;; hydrolase activity;; in utero embryonic development;; inner ear morphogenesis;; locomotory behavior;; nose development;; nucleic acid binding;; nucleotide binding;; nucleus;; palate development;; positive regulation of multicellular organism growth;; regulation of transcription, DNA-dependent;; sensory perception of sound;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; catalytic activity chromatin binding;; hydrolase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus adult behavior;; anatomical structure development;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of growth;; positive regulation of multicellular organismal process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; system process 302.5165 271.0408 277.1673 96.9872 129.5435 115.0347 0.0035536382 1.32497 8.14595 6.82098 1356556 1437821_at chr18:38032193-38032756 18 B3 IPA Mus musculus 7 days embryo whole body cDNA, RIKEN full-length enriched library, clone:C430005H19 product:unknown EST, full insert sequence. 82.1644 66.3981 73.2373 29.0849 21.7617 20.6855 0.0020038048 1.64385 6.20267 4.55882 1356563 1437833_at 19 B|19 2.0 cM chr19:5752075-5752356 19 A UG5 Mm.182396 16998 Ltbp3 Latent transforming growth factor beta binding protein 3 (Ltbp3), mRNA binding;; calcium ion binding;; extracellular region;; growth factor binding;; proteinaceous extracellular matrix;; skeletal system development;; transforming growth factor beta receptor signaling pathway;; transforming growth factor beta receptor signaling pathway extracellular region;; extracellular region part extracellular matrix;; extracellular region part binding ion binding;; protein binding biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 835.8576 789.2137 720.4744 122.8249 143.6006 174.2888 0.0010525991 2.42416 9.60806 7.18390 1356604 1437916_at 7 chr7:71051764-71051840 7 C UGA Mm.446212 Transcribed locus 369.8274 350.1241 354.2457 126.2876 210.4329 154.0408 0.031056468 1.16203 8.48368 7.32165 1356607 1437923_at 18 chr18:61745836-61746386 18 E1 UGA Mm.437042 Transcribed locus 1713.8843 1705.9656 1711.3184 569.3217 724.9167 772.0500 0.010061013 1.32433 10.74011 9.41577 1356671 1438039_at 12 17.0 cM chr12:52899719-52903413 12 C1 chr12:52844708-52930523 12 C1 RSQ Mm.249391 NM_144788 1 1 207304 Hectd1 HECT domain containing 1 (Hectd1), mRNA. ligase activity;; modification-dependent protein catabolic process;; neural tube closure catalytic activity ligase activity anatomical structure formation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; catabolic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process 1462.5408 1454.6406 1494.3118 660.0924 683.9703 631.4610 0.00023469249 1.15970 10.52199 9.36229 1371369 1438157_s_at 12 chr12:56590865-56590958 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 510.2973 504.4462 496.2075 153.8367 260.8984 266.0473 0.043708266 1.19347 8.97618 7.78271 1356796 1438268_at 2 chr2:37230581-37232466 2 B chr2:37225588-37278423 2 B RSQ Mm.288785 NM_001100591 1 1 319817 RP23-321B3.1 Rc3h2 ring finger and CCCH-type zinc finger domains 2 (Rc3h2), mRNA. cytoplasm;; DNA binding;; membrane;; metal ion binding;; nucleic acid binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding ion binding;; nucleic acid binding;; protein binding 100.4560 103.6976 100.7457 47.6367 36.7214 56.6343 0.024055487 1.13503 6.66708 5.53205 1356817 1438301_at 15 chr15:64021278-64021774 15 D1 UGA Mm.448964 Transcribed locus 184.2528 204.5817 197.6398 65.8815 75.6278 99.6244 0.01340227 1.30258 7.60960 6.30702 1356853 1438352_at 18 chr18:23965390-23965882 18 A2 UG5 Mm.475809 Transcribed locus 885.8741 970.5680 947.4409 302.6816 274.2473 253.1274 0.00022355676 1.75894 9.86718 8.10824 1356892 1438429_at 8 chr8:11622380-11622942 8 A1.1 UGA Mm.441154 Transcribed locus 88.5275 76.0028 82.3322 36.9443 33.9261 46.2234 0.0060298184 1.08575 6.35981 5.27405 1356918 1438470_at 10 C2|10 52.0 cM chr10:94850448-94851019 10 C2 UGA Mm.440128 216233 Socs2 Suppressor of cytokine signaling 2, mRNA (cDNA clone IMAGE:1068260) Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 54.4976 58.0697 61.0425 25.0141 30.9379 29.8878 0.002609536 1.02071 5.85319 4.83249 1356987 1438590_at 15 F1 chr15:97577164-97577499 15 F1 UGA Mm.24028 223864 Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), mRNA Phospholipase C-epsilon pathway Leukocyte transendothelial migration;; Long-term potentiation CLASS Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670] Cellular Processes; Nervous System; Long-term potentiation [PATH:mmu04720] cAMP binding;; cAMP-dependent protein kinase complex;; cAMP-dependent protein kinase regulator activity;; cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; membrane;; nucleotide binding;; regulation of protein amino acid phosphorylation;; regulation of small GTPase mediated signal transduction;; small GTPase mediated signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; nucleoside binding;; nucleoside-triphosphatase regulator activity;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 10167.4947 9930.5401 10434.9852 5070.0366 5987.5022 4184.7868 0.019275634 1.01734 13.31282 12.29549 1357030 1438704_at 4 chr4:133885037-133885355 4 D3 chr4:133871034-133885544 4 D3 RSQ Mm.331961 NM_001039048 1 1 433766 Trim63 tripartite motif-containing 63 (Trim63), mRNA. contractile fiber;; cytoplasm;; intracellular;; ligase activity;; metal ion binding;; modification-dependent protein catabolic process;; muscle contraction;; nucleus;; proteasomal ubiquitin-dependent protein catabolic process;; protein binding;; protein binding;; ubiquitin-protein ligase activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; metabolic process;; multicellular organismal process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; system process 1134.0408 1137.9143 1071.2015 190.5138 496.9837 337.1603 0.045176646 1.81212 10.12148 8.30937 1357088 1438796_at 4 B2 chr4:48098745-48099192 4 B1 UGA Mm.247261 18124 RP23-122N18.2 Nr4a3 Nuclear receptor subfamily 4, group A, member 3 (Nr4a3), mRNA adult behavior;; DNA binding;; inner ear morphogenesis;; ligand-dependent nuclear receptor activity;; mesoderm formation;; metal ion binding;; neuromuscular process controlling balance;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; receptor activity;; regulation of transcription, DNA-dependent;; semicircular canal morphogenesis;; sequence-specific DNA binding;; steroid hormone receptor activity;; transcription;; transcription activator activity;; transcription factor activity;; vestibular reflex;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription activator activity;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus adult behavior;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; system process 1755.6214 1879.8865 1887.1944 777.1228 898.0928 815.5303 0.00039592468 1.15064 10.84541 9.69477 1357272 1439153_at 13 chr13:47342806-47343264 13 A5 UGA Mm.444782 Transcribed locus 3573.6306 3884.1631 3800.3058 805.9278 988.0900 951.3946 0.00054159063 2.04052 11.87282 9.83230 1357281 1439163_at 9 A5.3|9 23.0 cM chr9:48462424-48462942 9 A5.3 UG5 Mm.457803 235320 Zbtb16 PLZF gene Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer anterior/posterior pattern formation;; DNA binding;; embryonic hindlimb morphogenesis;; embryonic limb morphogenesis;; embryonic pattern specification;; forelimb morphogenesis;; leg morphogenesis;; male germ-line stem cell division;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of transcription, DNA-dependent;; nucleus;; nucleus;; positive regulation of apoptosis;; protein binding;; protein binding;; regulation of transcription;; skeletal system development;; specific transcriptional repressor activity;; transcriptional repressor complex;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription repressor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; sexual reproduction 93.8105 84.3978 86.6970 34.5174 36.3144 50.8549 0.017572419 1.14289 6.46291 5.32001 1357282 1439165_at 9 chr9:59325563-59326112 9 B UG5 Mm.446631 Transcribed locus 224.4195 203.8168 177.7075 92.1145 91.9549 98.6644 0.0040887578 1.09396 7.65151 6.55756 1357340 1439238_at 15 E1 UG5 Mm.202715 223697 Unc84b Unc-84 homolog B (C. elegans), mRNA (cDNA clone IMAGE:5325151) condensed nuclear chromosome;; condensed nuclear chromosome;; endosome;; integral to membrane;; membrane;; nuclear chromosome, telomeric region;; nuclear chromosome, telomeric region;; nuclear envelope;; nuclear envelope;; nuclear envelope organization;; nucleus;; protein binding cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle envelope;; organelle part binding protein binding cellular component organization;; cellular process membrane organization;; organelle organization 294.8061 284.7694 265.5554 120.6256 125.0834 115.7700 4.8505589e-05 1.22463 8.13671 6.91209 1357416 1439349_at 10 C1 chr10:79534037-79534504 10 C1 UGA Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 205.9640 186.2001 225.0207 27.8535 75.4844 35.8652 0.030598228 2.27949 7.68029 5.40080 1357431 1439412_at chr9:112004583-112004658 9 F3 IPA ESTs 719.6030 732.3940 712.9608 366.9347 364.6460 348.3911 5.3792936e-05 1.00364 9.49507 8.49143 1357452 1439488_at 10 chr10:80257696-80258171 10 C1 UGA Mm.393160 Transcribed locus 1303.2630 1235.3102 1450.9852 617.0575 608.3186 576.7630 0.00099137721 1.14387 10.37380 9.22993 1357496 1439537_at chr6:31078869-31079400 6 A3.3 IPA ESTs 35.6331 50.8499 44.9737 17.9056 19.6579 16.9175 0.0066423458 1.25817 5.43811 4.17994 1357586 1439638_at 13 chr13:104615681-104616180 13 D1 UGA Mm.442245 Transcribed locus 734.1372 741.5407 600.4444 280.0701 234.0150 203.0847 0.0011224648 1.53938 9.42806 7.88868 1371475 1439740_s_at 1 H2.3 chr1:169153282-169153392 1 H2.3 UGA Mm.440156 80914 Uck2 Uridine-cytidine kinase 2, mRNA (cDNA clone IMAGE:3493906) Drug metabolism - other enzymes;; Metabolic pathways CLASS Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - other enzymes [PATH:mmu00983];; Pyrimidine metabolism ATP binding;; kinase activity;; metabolic process;; nucleotide binding;; phosphotransferase activity, alcohol group as acceptor;; transferase activity;; uridine kinase activity binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity metabolic process 71.5221 61.6221 59.3640 38.8723 26.8697 24.8823 0.01874233 1.11053 5.99907 4.88854 1357855 1439933_at 6 chr6:93867831-93868325 6 D1 UGA Mm.448178 Transcribed locus 187.0768 211.0408 218.6582 92.4490 110.0140 87.4484 0.0014459286 1.09297 7.68047 6.58750 1357909 1439998_at 10 B5.1 chr10:66653931-66654467 10 B5.1 UGA Mm.23846 108829 Jmjd1c Jumonji domain containing 1C, mRNA (cDNA clone IMAGE:3676222) chromatin modification;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 179.3804 127.1099 127.7575 53.4462 63.6421 72.3086 0.0055674282 1.18868 7.15803 5.96934 1357929 1440018_at chr3:107243345-107243772 3 F2.3 IPA A330043J11Rik RIKEN cDNA A330043J11 gene 305.5309 299.4029 318.1556 64.0072 65.2502 54.0433 0.00060293683 2.33686 8.26490 5.92804 1357961 1440051_at IPA Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230017C05 product:hypothetical protein, full insert sequence. 68.3447 62.2854 61.3614 25.6397 26.0670 24.4425 0.00010791921 1.33302 5.99828 4.66526 1358021 1440111_at chr2:52800127-52800424 2 C1.1 IPA ESTs 345.2491 378.4152 371.7546 145.4263 144.2862 87.4598 0.020527676 1.57535 8.51118 6.93583 1358101 1440225_at 17 B3 chr17:43595923-43596473 17 B3 UG5 Mm.23478 224792 Gpr116 G protein-coupled receptor 116 (Gpr116), mRNA integral to membrane;; membrane;; plasma membrane cell;; cell part cell part;; membrane;; membrane part 402.5401 470.9924 448.4297 65.0852 78.3354 77.9224 3.4575875e-05 2.58049 8.78043 6.19994 1358216 1440347_at 8 chr8:79889434-79889899 8 C1 UGA Mm.438679 Transcribed locus 116.9287 112.6836 119.9223 31.0515 38.0452 42.1382 0.0046176656 1.66276 6.86386 5.20110 1358233 1440365_at chr16:37873054-37873603 16 B3 IPA ESTs 124.9121 111.1290 85.0647 44.0676 50.3311 48.5479 0.012329639 1.15166 6.72378 5.57212 1358405 1440543_at 12 C1 chr12:53010825-53011204 12 C1 UGA Mm.131941 320487 Heatr5a HEAT repeat containing 5A, mRNA (cDNA clone MGC:99412 IMAGE:30544145) 133.4714 137.0678 119.5531 50.3233 46.2386 62.3984 0.0034014386 1.30434 7.02021 5.71587 1358568 1440708_at 15 E1|15 43.3 cM UGA Mm.29677 17886 AL583886.1 Myh9 Myosin, heavy polypeptide 9, non-muscle, mRNA (cDNA clone IMAGE:4913872) Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Tight junction actin binding;; actin filament binding;; actin filament-based movement;; actin-dependent ATPase activity;; ADP binding;; ATP binding;; calmodulin binding;; cell adhesion;; cell cortex;; cell morphogenesis involved in differentiation;; cell motion;; cell-cell adherens junction;; cell-cell adhesion;; cortical cytoskeleton;; cytoplasm;; establishment of meiotic spindle localization;; establishment of T cell polarity;; immunological synapse;; immunological synapse;; in utero embryonic development;; meiotic metaphase I;; meiotic spindle organization;; microfilament motor activity;; motor activity;; myoblast fusion;; myosin complex;; neuromuscular junction;; nucleotide binding;; plasma membrane;; plasma membrane;; protein binding;; regulation of cell shape;; spindle;; stress fiber;; stress fiber;; uropod;; uropod;; uropod organization cell;; cell part;; macromolecular complex;; organelle;; organelle part;; synapse cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; neuromuscular junction;; non-membrane-bounded organelle;; organelle part;; protein complex;; trailing edge binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; protein binding anatomical structure formation;; biological adhesion;; biological regulation;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; multicellular organismal process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell activation;; cell adhesion;; cell cycle;; cell cycle process;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; cellular localization;; embryonic development;; establishment of localization;; establishment of localization in cell;; establishment of organelle localization;; establishment or maintenance of cell polarity;; leukocyte activation;; localization of cell;; membrane organization;; microtubule-based process;; multicellular organismal development;; organelle organization;; regulation of biological process;; regulation of biological quality;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; syncytium formation;; transport 110.7055 109.2433 106.8279 40.1665 61.6805 47.5811 0.022923912 1.15138 6.76704 5.61566 1358586 1440728_at 14 UG5 Mm.400861 Transcribed locus 403.3556 533.3844 408.7996 62.5685 100.1319 105.9936 0.0029840383 2.34974 8.79673 6.44699 1358631 1440776_at 5 C3.1 chr5:67139353-67139604 5 C3.1 UGA Mm.374778 77569 Limch1 LIM and calponin homology domains 1 (Limch1), mRNA actin binding;; actomyosin structure organization;; metal ion binding;; zinc ion binding binding ion binding;; protein binding cellular component organization;; cellular process actin filament-based process;; organelle organization 319.0408 320.0548 340.7781 191.4574 181.4777 117.9626 0.040931472 1.02858 8.35082 7.32224 1371567 1440818_s_at 1 28.9 cM chr1:55043911-55044022 1 C1.2 chr1:55042012-55084322 1 C1.2 RSQ Mm.279736 NM_031179 1 1 81898 Sf3b1 splicing factor 3b, subunit 1 (Sf3b1), mRNA. anterior/posterior pattern formation;; binding;; chromatin binding;; mRNA processing;; nuclear mRNA splicing, via spliceosome;; nucleus;; protein binding;; RNA splicing;; RNA splicing factor activity, transesterification mechanism;; spliceosomal complex cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding;; catalytic activity chromatin binding;; protein binding;; RNA splicing factor activity, transesterification mechanism cellular process;; developmental process;; metabolic process;; multicellular organismal process cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process 156.4297 164.7850 147.7269 89.4151 77.5550 66.0139 0.0086147713 1.01877 7.28687 6.26810 1358665 1440847_at 15 chr15:58884333-58884882 15 D1 UGA Mm.394414 Transcribed locus 96.5529 96.5024 103.6766 60.6681 39.3869 42.1065 0.027192156 1.08774 6.62723 5.53949 1358691 1440878_at 16 62.2 cM chr16:92601752-92602086 16 C4 chr16:92601710-92826311 16 C4 RSQ Mm.4081 NM_001111022 4 1 12394 Runx1 runt related transcription factor 1 (Runx1), transcript variant 2, mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mmu05220];; Chronic myeloid leukemia;; Pathways in cancer ATP binding;; behavioral response to pain;; central nervous system development;; definitive hemopoiesis;; DNA binding;; embryonic hemopoiesis;; in utero embryonic development;; liver development;; neuron development;; neuron differentiation;; nucleus;; positive regulation of angiogenesis;; protein binding;; regulation of transcription, DNA-dependent;; response to retinoic acid;; skeletal system development;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; multicellular organismal response to stress;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress 402.8916 413.1497 410.4421 221.3186 225.9248 161.7630 0.021885494 1.02613 8.67527 7.64914 1358736 1440926_at 5 chr5:148446897-148447256 5 G3 UGA Mm.458302 Transcribed locus 42.8220 42.6328 54.9066 15.8568 30.1893 22.2342 0.039881441 1.07846 5.53769 4.45924 1358830 1441030_at 15 A2 chr15:10619119-10619604 15 A1 UGA Mm.212395 75646 Rai14 Retinoic acid induced 14 (Rai14), mRNA cytoplasm;; cytoskeleton;; mitochondrion cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle 63.4025 82.1758 77.4065 21.4368 26.5328 20.5512 0.00044849522 1.70287 6.20716 4.50429 1358927 1441129_at 5 chr5:93535215-93535741 5 E2 UGA Mm.450589 Transcribed locus 237.6343 201.2525 205.6262 99.8509 107.9631 104.6264 0.0016593199 1.04138 7.74311 6.70173 1359019 1441230_at chr3:27511416-27511951 3 A3 IPA ESTs 55.0467 58.0709 41.4609 21.1906 26.7098 19.2163 0.0043846322 1.20237 5.67200 4.46963 1359020 1441231_at 11 A1|11 chr11:5327308-5327648 11 A1 UG5 Mm.425674 100042016 100042016 PREDICTED: Mus musculus hypothetical protein LOC100042016 (LOC100042016), mRNA 105.4356 107.4385 109.9678 60.5906 50.5981 44.9012 0.012513214 1.05927 6.74951 5.69024 1371605 1441315_s_at 1 87.0 cM chr1:166195326-166195426 1 H2.2 chr1:166179185-166195500 1 H2.2 RSQ Mm.35444 NM_054087 1 1 116914 Slc19a2 solute carrier family 19 (thiamine transporter), member 2 (Slc19a2), mRNA. plasma membrane;; thiamin transmembrane transporter activity;; thiamin transport cell;; cell part cell part;; membrane transporter activity substrate-specific transporter activity;; transmembrane transporter activity;; vitamin transporter activity establishment of localization;; localization establishment of localization;; transport 350.0812 335.9187 360.3314 87.3463 84.5908 84.5109 8.2756879e-06 2.02818 8.44556 6.41739 1359131 1441360_at chrX:155711702-155712021 X F4 IPA ESTs, Moderately similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus] 110.9231 122.6275 113.0433 40.2513 37.9703 49.8934 0.0030787549 1.44458 6.85076 5.40618 1359142 1441372_at 18 chr18:68108128-68108625 18 E2 UGA Mm.446015 Transcribed locus 61.2249 72.2706 67.9515 17.8593 30.5035 28.6184 0.021291402 1.42315 6.06594 4.64279 1359145 1441375_at chr6:94636705-94637233 6 D2 IPA ESTs 61.5857 66.7412 60.4484 17.0989 20.1133 23.2670 0.0029259937 1.65218 5.97422 4.32204 1359158 1441388_at 18 E2|18 44.0 cM chr18:70788193-70788698 18 E2 UGA Mm.322 17191 Mbd2 Methyl-CpG binding domain protein 2 (Mbd2), mRNA cellular protein complex assembly;; chromatin;; chromatin binding;; cytoplasm;; DNA binding;; heterochromatin;; histone deacetylase complex;; maternal behavior;; methyl-CpG binding;; mRNA binding;; negative regulation of transcription from RNA polymerase II promoter;; nucleolus;; nucleus;; positive regulation of Wnt receptor signaling pathway;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; siRNA binding;; transcription cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding chromatin binding;; nucleic acid binding;; nucleotide binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus behavior;; biosynthetic process;; cell communication;; cell proliferation;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organism reproduction;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive behavior;; reproductive process;; reproductive process in a multicellular organism 98.7170 102.9127 90.3403 34.1662 30.8210 27.0988 0.00046337603 1.66910 6.60260 4.93350 1359231 1441467_at 3 chr3:138436873-138437414 3 H1 UG5 Mm.417274 Transcribed locus 178.3306 189.0532 180.0455 88.5520 100.7077 79.9473 0.005721998 1.02994 7.51109 6.48115 1359271 1441507_at 11 A3.3|11 13.0 cM chr11:30117994-30118404 11 A3.3 UGA Mm.123110 20742 RP23-189P1.1 Spnb2 Mus musculus, clone IMAGE:4951562, mRNA Tight junction CLASS Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] actin binding;; actin filament capping;; calmodulin binding;; common-partner SMAD protein phosphorylation;; cortical cytoskeleton;; cytoplasm;; cytoskeleton;; membrane;; nucleus;; plasma membrane;; protein binding;; SMAD protein nuclear translocation;; spectrin;; structural constituent of cytoskeleton cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; structural molecule activity protein binding;; structural constituent of cytoskeleton anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cellular component assembly;; cellular component disassembly;; cellular localization;; cellular macromolecular complex subunit organization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecular complex subunit organization;; macromolecule localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of cellular component biogenesis;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; transport 86.6902 102.3660 115.2089 36.9799 58.6760 51.3774 0.015726337 1.06569 6.65450 5.58881 1359292 1441529_at chr11:22757572-22758125 11 A3.2 IPA ESTs 295.8671 252.2945 262.4004 63.4255 79.3802 85.1542 0.00095211134 1.83790 8.07447 6.23657 1359294 1441531_at 2 F3|2 77.0 cM chr2:135486868-135487311 2 F3 UGA Mm.38009 18798 RP23-7A19.1 Plcb4 Phospholipase C beta 4 [Mus musculus], mRNA sequence Alzheimer's disease;; Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Huntington's disease CLASS Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism [PATH:mmu00562] Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Environmental Information Processing; Signal Tr;; Inositol phosphate metabolism;; Long-term depression;; Long-term potentiation;; Melanogenesis;; Metabolic pathways;; Phosphatidylinositol signaling system;; Vascular smooth muscle contraction;; Wnt signaling pathway dendrite;; microsome;; nucleus;; postsynaptic density;; protein binding;; signal transducer activity;; signal transduction;; smooth endoplasmic reticulum cell;; cell part;; organelle;; organelle part;; synapse;; synapse part cell fraction;; cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; postsynaptic density;; synapse part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 173.8961 194.4956 192.6397 72.5843 105.3909 92.1812 0.013941737 1.06928 7.54515 6.47586 1359354 1441592_at 10 chr10:66595201-66595683 10 B5.1 UGA Mm.440483 Transcribed locus 266.1519 287.5964 250.5536 121.7676 132.4307 119.1528 0.0001543038 1.10641 8.06433 6.95792 1359356 1441594_at chr5:104199317-104199794 5 E5 IPA Mus musculus 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130072L14 product:unclassifiable, full insert sequence. 295.7682 330.0745 288.4852 43.1577 49.2335 33.4377 0.0012348887 2.87694 8.24911 5.37217 1359551 1441799_at chr17:28557117-28557366 17 A3.3 IPA ESTs 244.3128 237.3712 216.6854 111.3767 148.9563 91.4507 0.031623355 1.01669 7.86102 6.84432 1359571 1441823_at 14 A3 chr14:26357806-26357946 14 A3 UGA Mm.227484 328365 Zmiz1 Zinc finger, MIZ-type containing 1, mRNA (cDNA clone MGC:86031 IMAGE:6856060) artery morphogenesis;; cell aging;; cytoplasm;; developmental growth;; heart morphogenesis;; in utero embryonic development;; metal ion binding;; nucleus;; positive regulation of fibroblast proliferation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; vasculogenesis;; vitellogenesis;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; protein binding biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process aging;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell aging;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytoplasm organization;; developmental growth;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 419.7053 421.7728 441.5506 147.9853 74.7760 87.1173 0.018845426 2.11376 8.74000 6.62623 1371637 1441843_s_at 2 chr2:52729244-52729333 2 C1.1 UGA Mm.274277 Transcribed locus 157.2023 157.9271 156.1753 20.3063 20.1412 27.7300 0.0028937442 2.80577 7.29554 4.48977 1359586 1441858_at IPA Unknown 65.5719 61.6627 60.3553 21.1196 17.6383 18.1671 0.00047838982 1.72411 5.96558 4.24147 1371720 1441956_s_at 5 G2|5 78.0 cM chr5:136958783-136958847 5 G2 UGA Mm.320317 13047 Cux1 CDNA fis, clone TRACH2005314,highly similar to Mus musculus mCASP (cux) mRNA auditory receptor cell differentiation;; chromatin binding;; DNA binding;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; intra-Golgi vesicle-mediated transport;; lung development;; membrane;; multicellular organismal development;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; regulation of transcription;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription regulator activity;; transcription repressor activity;; transport cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; transcription regulator activity chromatin binding;; nucleic acid binding;; transcription factor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport;; vesicle-mediated transport 446.4232 420.8379 429.3190 148.0572 154.5219 183.6745 0.0027521772 1.42087 8.75510 7.33423 1359623 1441976_at 15 chr15:36180185-36180568 15 B3.1 UGA Mm.440854 Transcribed locus 44.3586 44.2345 54.2114 20.3846 22.7303 20.3275 0.0015889793 1.16582 5.56626 4.40044 1359760 1442121_at 9 59.0 cM IPA Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C 304.1689 325.3140 353.0964 110.9662 114.2588 115.7375 0.00079712253 1.52450 8.35278 6.82828 1359813 1442176_at 10 chr10:67558667-67559135 10 B5.1 chr10:67558340-67741474 10 B5.1 RSQ Mm.440357 NM_023598 1 1 71371 Arid5b AT rich interactive domain 5B (MRF1-like) (Arid5b), mRNA. DNA binding;; face morphogenesis;; fibroblast migration;; intracellular;; kidney development;; multicellular organism growth;; muscle organ morphogenesis;; nitrogen compound metabolic process;; nucleus;; palate development;; platelet-derived growth factor receptor signaling pathway;; post-embryonic development;; regulation of transcription, DNA-dependent;; skeletal system morphogenesis;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding biological regulation;; cellular process;; developmental process;; growth;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell motility;; cell motion;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; post-embryonic development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 172.1911 167.7231 158.4300 69.5626 67.8512 64.5644 1.181016e-05 1.30277 7.37517 6.07240 1359818 1442181_at chr7:17108708-17109244 7 A2 IPA ESTs 140.4297 115.5820 141.8017 51.4498 54.6219 71.2926 0.0040737537 1.17401 7.04474 5.87073 1359876 1442241_at 5 chr5:23092186-23092646 5 A3 UGA Mm.443009 Transcribed locus 486.8951 448.0872 449.9860 184.1371 184.4923 222.1304 0.0016929202 1.23384 8.84961 7.61577 1359922 1442288_at 11 B1.3|11 29.5 cM chr11:54844602-54845026 11 B1.3 UGA Mm.265347 11749 Anxa6 Annexin A6, mRNA (cDNA clone MGC:6574 IMAGE:3482035) calcium ion binding;; calcium ion transport;; calcium-dependent phospholipid binding;; cytoplasm;; perinuclear region of cytoplasm;; regulation of muscle contraction cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; lipid binding biological regulation;; establishment of localization;; localization;; multicellular organismal process;; regulation of biological process establishment of localization;; regulation of biological process;; regulation of multicellular organismal process;; system process;; transport 88.3980 99.7794 88.2863 49.5876 49.3882 39.4287 0.0036576778 1.00385 6.52358 5.51973 1359942 1442309_at 12 chr12:3829047-3829288 12 A1.1 UGA Mm.443753 Transcribed locus 75.2059 58.8194 76.4777 30.3606 28.3610 28.2900 0.0061382665 1.26526 6.12265 4.85739 1359967 1442336_at chr15:77657346-77657609 15 E1 IPA ESTs, Weakly similar to I58401 protein-tyrosine kinase (EC 2.7.1.112) JAK3 - mouse [M.musculus] 352.1864 379.1085 349.1038 129.0508 139.6671 156.4074 0.00083664117 1.34912 8.49139 7.14227 1360008 1442382_at 13 D1 chr13:103559646-103562570 13 D1 UGA Mm.202606 328329 Mast4 MKIAA0303 protein ATP binding;; cytoplasm;; kinase activity;; magnesium ion binding;; metal ion binding;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; transferase activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 635.3268 556.4423 554.1874 67.0231 172.8667 154.7860 0.032253691 2.25715 9.18189 6.92474 1360020 1442395_at 1 chr1:34085393-34085906 1 B UGA Mm.436779 Transcribed locus 810.7263 796.9055 809.7142 403.2840 306.6368 398.7561 0.012432653 1.13573 9.65420 8.51847 1360303 1442700_at 4 C6|4 46.8 cM chr4:102243528-102243998 4 C6 UGA Mm.20181 18578 RP23-57D24.1 Pde4b Phosphodiesterase 4B, cAMP specific, mRNA (cDNA clone IMAGE:5354427) Purine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] 3',5'-cyclic-AMP phosphodiesterase activity;; smooth muscle contraction catalytic activity hydrolase activity multicellular organismal process system process 1114.5956 1047.2592 1032.7740 291.8388 239.1054 373.2075 0.0083254007 1.84422 10.05567 8.21145 1360313 1442710_at chr3:142052865-142053312 3 H1 IPA ESTs 108.3114 94.5578 86.2277 17.9689 22.0659 24.8968 0.00040049656 2.16106 6.58408 4.42302 1360328 1442725_at 11 UG5 Mm.419280 Transcribed locus 163.2630 158.7630 159.4576 36.7855 44.6911 34.0372 0.0029006618 2.06893 7.32627 5.25734 1360350 1442750_at 13 A1 chr13:14064362-14064580 13 A1 UG5 Mm.21686 97884 B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2, mRNA (cDNA clone MGC:103263 IMAGE:30735904) acetylgalactosaminyltransferase activity;; galactosyltransferase activity;; Golgi apparatus;; integral to membrane;; membrane;; protein amino acid glycosylation;; transferase activity;; transferase activity, transferring glycosyl groups;; UDP-N-acetylgalactosamine metabolic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 190.0408 204.3828 202.6011 93.3454 97.1084 97.3405 5.9055846e-05 1.05226 7.63593 6.58367 1371742 1442760_x_at chr11:29616149-29616353 11 A3.3 IPA ESTs 50.7236 53.3655 54.1636 18.2843 21.4093 21.6638 0.0012728203 1.37059 5.72056 4.34997 1360461 1442880_at 16 chr16:34559830-34560160 16 B3 UGA Mm.24752 Transcribed locus 215.5388 208.2831 213.1139 67.4483 66.3242 65.9911 4.8389121e-07 1.67277 7.72990 6.05712 1360495 1442916_at 8 chr8:70533034-70533494 8 B3.3 UGA Mm.403977 Transcribed locus 46.3576 71.5632 75.0926 26.5192 29.7341 35.3256 0.023539672 1.05361 5.97549 4.92188 1360531 1442956_at chr12:113090683-113091202 12 F1 IPA Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930009B01 product:unknown EST, full insert sequence. 110.8251 106.4425 105.9811 18.8508 23.0231 24.8187 0.0020931879 2.28627 6.75124 4.46497 1360542 1442967_at 8 chr8:80016360-80016899 8 C1 UGA Mm.394850 Transcribed locus 172.1387 207.6292 189.9008 47.5895 50.3558 77.0885 0.0091682908 1.73310 7.56480 5.83170 1360637 1443069_at 11 chr11:108041099-108041513 11 E1 UGA Mm.447682 Transcribed locus 236.1724 255.5325 243.2201 71.4720 100.2443 83.6406 0.0060295051 1.53812 7.93573 6.39760 1360727 1443159_at 10 C1 chr10:82357178-82357468 10 C1 UGA Mm.210155 50493 Txnrd1 Thioredoxin reductase 1, mRNA (cDNA clone MGC:46868 IMAGE:5059831) Pyrimidine metabolism CLASS Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] cell proliferation;; cell redox homeostasis;; cytoplasm;; cytosol;; FAD binding;; gastrulation;; mesoderm formation;; NADP or NADPH binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; selenium binding;; thioredoxin-disulfide reductase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle antioxidant activity;; binding;; catalytic activity cofactor binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity;; selenium binding;; thioredoxin-disulfide reductase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; cellular homeostasis;; embryonic development;; multicellular organismal development;; oxidation reduction;; regulation of biological process;; regulation of biological quality;; regulation of cellular process 189.0735 161.3662 150.8610 66.0016 54.3055 60.7490 0.00036639432 1.46728 7.37802 5.91075 1360752 1443184_at 3 G1 chr3:116122738-116123185 3 G1 UGA Mm.17647 229776 Cdc14a CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), mRNA Cell cycle CLASS Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] cell cycle;; cell division;; dephosphorylation;; hydrolase activity;; nucleus;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity cellular process;; metabolic process cell cycle;; cell division;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 85.4342 95.8322 90.8806 17.2148 22.3893 21.5777 0.00092177589 2.16110 6.50169 4.34060 1360780 1443212_at chr8:75853675-75854162 8 B3.3 IPA ESTs 379.3940 467.5063 384.8710 127.9102 182.0265 147.5609 0.0022710252 1.43749 8.67488 7.23739 1360856 1443289_at 13 chr13:110571699-110572038 13 D2.2 UGA Mm.438644 Transcribed locus 1352.6141 1341.0749 1312.3666 553.2205 721.0148 717.3226 0.014247984 1.01886 10.38289 9.36402 1360866 1443299_at 8 B1.1 chr8:46988445-46988717 8 B1.1 UGA Mm.282900 53318 Pdlim3 PDZ and LIM domain 3 (Pdlim3), mRNA actin cytoskeleton;; actin filament organization;; cytoplasm;; cytoskeletal protein binding;; heart development;; metal ion binding;; protein binding;; skeletal muscle tissue development;; structural constituent of muscle;; structural constituent of muscle;; Z disc;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; structural molecule activity ion binding;; protein binding;; structural constituent of muscle cellular component organization;; cellular process;; developmental process;; multicellular organismal process actin filament-based process;; anatomical structure development;; multicellular organismal development;; organelle organization 81.0221 90.9414 77.0503 32.7734 37.0729 24.2394 0.0085988014 1.42294 6.37161 4.94868 1360905 1443341_at chr6:86724341-86724697 6 D1 IPA ESTs 69.6108 58.2016 72.3165 35.1483 34.1171 26.4292 0.0036538216 1.06954 6.05349 4.98396 1360981 1443430_at 10 chr10:94753539-94754027 10 C2 IPA Mm.218009 Transcribed locus, strongly similar to NP_034080.1 CASP2 and RIPK1 domain containing adaptor with death domain [Mus musculus] 326.0674 351.6342 316.6741 130.7251 182.4987 137.0706 0.011175876 1.15763 8.37127 7.21364 1361015 1443471_at 16 B4|16 28.9 cM chr16:43613020-43613517 16 B4 UGA Mm.440824 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 481.5816 499.9571 426.7572 179.0172 203.0281 161.4058 0.00051818212 1.37684 8.87152 7.49468 1361044 1443503_at 17 A3.3 IPA Mm.209679 Ip6k3 Inositol hexaphosphate kinase 3, mRNA (cDNA clone MGC:176224 IMAGE:9055875) 186.4252 175.2630 147.1039 58.2837 71.0292 59.2253 0.00051015016 1.43101 7.39884 5.96784 1361052 1443511_at 9 chr9:68763941-68764383 9 C UGA Mm.445349 Transcribed locus 119.9270 158.5883 164.7428 75.3302 65.3387 74.2698 0.0091789238 1.03317 7.19308 6.15991 1361083 1443544_at chr18:68137416-68137770 18 E2 IPA ESTs 74.4958 82.3863 65.4243 17.8622 21.3373 27.4897 0.0031198216 1.75340 6.20506 4.45165 1361128 1443593_at chr16:22134185-22134615 16 B1 IPA Mus musculus 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430085A14 product:unknown EST, full insert sequence. 69.8172 64.1338 70.7098 22.9933 18.6346 16.6335 0.0028829094 1.82443 6.09079 4.26636 1361161 1443630_at chr3:136399370-136399659 3 G3 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 125.6585 163.4560 133.2735 48.2582 41.7653 33.6439 0.0010020525 1.77839 7.12812 5.34974 1371794 1443721_x_at 10 C1 chr10:79529116-79529323 10 C1 UG5 Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 157.5485 150.5914 154.0703 73.3026 79.7444 60.4124 0.0095634842 1.12391 7.26720 6.14329 1361305 1443848_at chr17:3296637-3296684 17 A1 IPA ESTs 56.7601 49.6189 54.2289 24.0501 23.1634 28.5558 0.0013806693 1.08772 5.74020 4.65249 1361356 1443905_at 5 chr5:130054203-130054757 5 G1.3 UGA Mm.441771 Transcribed locus 6060.1090 6164.7448 6182.4311 2017.0201 3019.9332 3655.0646 0.046812008 1.12497 12.58297 11.45800 1361527 1444083_at 2 44.0 cM chr2:76783445-76783867 2 C3 RSQ Mm.373672 NM_028004 2 1 22138 RP23-82M15.1 Ttn titin (Ttn), transcript variant N2-B, mRNA. A band;; adult heart development;; ATP binding;; calcium ion binding;; calmodulin binding;; cardiac myofibril assembly;; cytoplasm;; forward locomotion;; heart morphogenesis;; I band;; in utero embryonic development;; kinase activity;; M band;; magnesium ion binding;; metal ion binding;; muscle contraction;; muscle myosin complex;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; sarcomere;; sarcomere organization;; sarcomere organization;; somitogenesis;; striated muscle cell development;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity;; Z disc cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; locomotion;; metabolic process;; multicellular organismal process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; directional locomotion;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; pattern specification process;; primary metabolic process;; system process 50.4729 49.4122 48.9142 23.0751 23.0046 27.6615 0.0064026567 1.01816 5.63214 4.61398 1361603 1444164_at 12 chr12:66171717-66172185 12 C1 UGA Mm.442333 Transcribed locus 99.2769 93.9087 95.8318 49.8596 51.7712 41.2516 0.0072249143 1.02292 6.58967 5.56675 1361781 1444349_at chr15:96135816-96136234 15 F1 IPA ESTs, Highly similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus] 62.7367 68.4653 71.2794 19.3327 25.2033 36.4604 0.031272501 1.36906 6.07465 4.70559 1361787 1444355_at 5 C3.1 chr5:68196657-68197155 5 C3.1 UGA Mm.153230 11980 Atp8a1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (Atp8a1), transcript variant 2, mRNA ATP binding;; ATP biosynthetic process;; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;; catalytic activity;; cytoplasmic vesicle;; hydrolase activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; integral to membrane;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; nucleotide binding;; phospholipid transport;; phospholipid-translocating ATPase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; vesicle binding;; catalytic activity;; transporter activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; nitrogen compound metabolic process;; primary metabolic process;; transport 234.3698 213.4930 173.1746 65.1724 78.1472 79.7813 0.001183738 1.47149 7.68226 6.21076 1361920 1444489_at 2 C2 UGA Mm.30928 78830 RP23-299A2.2 Slc25a12 Solute carrier family 25 (mitochondrial carrier, Aralar), member 12, mRNA (cDNA clone MGC:67718 IMAGE:6311836) binding;; calcium ion binding;; integral to membrane;; malate-aspartate shuttle;; membrane;; mitochondrial inner membrane;; mitochondrial inner membrane;; mitochondrion;; mitochondrion;; transport;; transporter activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; transporter activity ion binding cellular process;; establishment of localization;; localization;; metabolic process cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; oxidation reduction;; transport 144.7766 153.0817 115.2967 43.3699 54.6411 49.9505 0.00097202554 1.47736 7.09502 5.61766 1362068 1444645_at 11 chr11:20451270-20451705 11 A3.1 UG5 Mm.449965 Transcribed locus 86.7458 93.7287 89.3794 35.8851 48.9263 41.5563 0.0098566834 1.10539 6.49034 5.38495 1362172 1444749_at 16 chr16:31305712-31306199 16 B2 UGA Mm.436754 Transcribed locus 958.4100 945.1917 902.3013 136.0379 172.2246 167.8797 0.0010411162 2.56638 9.86881 7.30243 1362387 1444973_at chr14:24571790-24572277 14 A3 IPA ESTs 46.4887 45.2973 41.1405 14.8656 19.4000 22.6184 0.013621896 1.24378 5.46755 4.22377 1362441 1445028_at 11 chr11:107899559-107900120 11 E1 UGA Mm.448692 Transcribed locus 248.1519 219.4084 234.4187 104.4197 93.6171 96.9214 5.9265989e-05 1.25060 7.86850 6.61790 1362558 1445148_at chr1:55487728-55488266 1 C1.2 IPA Mus musculus 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230091K16 product:unknown EST, full insert sequence. 100.3992 94.9140 98.7907 34.1323 33.0605 34.5397 1.7754817e-06 1.53139 6.61482 5.08343 1362606 1445200_at chr14:121449800-121450181 14 E5 IPA ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 197.2977 203.6983 210.3972 82.1361 121.9641 101.4529 0.022785558 1.01886 7.67050 6.65164 1362679 1445273_at chr10:66562127-66562494 10 B5.1 IPA ESTs, Moderately similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus] 328.6624 337.6353 313.1603 69.2576 82.7807 94.5636 0.0027573921 2.00074 8.35018 6.34945 1362797 1445395_at 11 chr11:108132382-108132923 11 E1 UGA Mm.443896 Transcribed locus 351.0118 343.7526 347.9196 78.4704 83.7358 76.9620 0.00014939259 2.12510 8.44107 6.31597 1362800 1445398_at 5 chr5:67306909-67307387 5 C3.1 UGA Mm.454791 Transcribed locus 360.0408 421.2584 402.3972 160.0409 168.0797 184.0005 0.00019300245 1.20806 8.62102 7.41295 1362845 1445443_at chr7:52694090-52694571 7 B4 IPA ESTs, Weakly similar to I58401 protein-tyrosine kinase (EC 2.7.1.112) JAK3 - mouse [M.musculus] 1148.0142 1246.0130 1230.3134 114.9731 143.4127 168.1867 0.0017046598 3.10325 10.23761 7.13437 1362958 1445562_at chr9:48638602-48638777 9 A5.3 IPA ESTs 29.0072 21.0493 22.7311 9.6515 9.8637 10.6158 0.0077753575 1.25987 4.58688 3.32701 1362992 1445598_at chr8:60092946-60093299 8 B2 IPA ESTs 185.1367 191.9254 193.2910 91.6914 96.0601 95.8460 4.8650289e-06 1.00808 7.57049 6.56241 1362994 1445600_at chr7:75180133-75180541 7 D1 IPA ESTs 93.4520 109.2569 88.0225 38.5707 58.2108 39.0783 0.015613648 1.11886 6.59251 5.47365 1363080 1445695_at 13 chr13:45701247-45701513 13 A5 UGA Mm.453409 Transcribed locus 321.4407 327.4148 322.8254 74.9895 76.0959 120.0523 0.013711582 1.87737 8.33933 6.46196 1363152 1445774_at chr14:24589566-24590021 14 A3 IPA Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330037B11 product:unknown EST, full insert sequence. 78.9087 61.2710 75.7856 28.5508 34.7242 40.9233 0.0060782452 1.05831 6.16103 5.10272 1363227 1445850_at 1 F chr1:136676358-136676868 1 E4 UGA Mm.188709 329251 Ppp1r12b Protein phosphatase 1, regulatory (inhibitor) subunit 12B, mRNA (cDNA clone MGC:175633 IMAGE:40131049) Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] cytoplasm cell;; cell part cell part;; intracellular;; intracellular part 386.1633 352.0731 311.2328 80.9814 94.9356 85.5210 0.0001011392 2.00268 8.44488 6.44220 1363243 1445866_at chr13:103556977-103557456 13 D1 IPA ESTs 221.0408 199.6425 195.1083 75.5634 88.6640 109.6386 0.0099998021 1.18369 7.67919 6.49550 1363268 1445892_at 1 C5 chr1:93338360-93338775 1 D IPA Mm.218141 Per2 Period homolog 2 (Drosophila) (Per2), mRNA 81.4570 85.1962 91.2654 28.9049 35.0073 45.7674 0.017825043 1.25787 6.42423 5.16636 1363275 1445900_at chr16:34085173-34085489 16 B3 IPA ESTs 132.3950 120.9487 139.6691 48.6278 58.2343 56.3075 0.0003348494 1.27002 7.03094 5.76092 1363294 1445919_at chr8:60059065-60059586 8 B2 IPA ESTs 449.1228 455.1874 446.7451 107.9912 133.3187 110.7071 0.0022793629 1.94683 8.81486 6.86804 1363341 1445966_at 17 chr17:12945147-12945628 17 A1 UGA Mm.411497 Transcribed locus 44.5572 45.8407 46.6734 24.1846 22.2959 22.0364 0.00032741341 1.00138 5.51356 4.51218 1363468 1446095_at 17 chr17:12957498-12957975 17 A1 UGA Mm.394955 Transcribed locus 54.2646 52.1852 50.3571 20.1831 29.0232 29.2576 0.025797799 1.01889 5.70721 4.68832 1363480 1446107_at chr14:121705469-121706005 14 E5 IPA ESTs 103.2695 124.3964 120.8903 48.6263 42.3994 57.1995 0.0020724092 1.23969 6.85554 5.61586 1363491 1446118_at chr17:30161295-30161855 17 A3.3 IPA ESTs 435.5323 428.8620 401.3469 90.0582 91.8387 103.4748 5.0772311e-05 2.15092 8.71990 6.56898 1363514 1446141_at chr1:188503427-188503922 1 H5 IPA Mus musculus 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130049J04 product:unclassifiable, full insert sequence. 125.8149 125.1290 127.4106 25.7968 22.3451 38.6829 0.01172417 2.16371 6.97859 4.81488 1363536 1446167_at chr6:38733170-38733515 6 B1 IPA Mus musculus 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930417E23 product:unknown EST, full insert sequence. 107.6002 111.5327 116.1609 31.5076 28.9785 35.8248 0.00088635164 1.80447 6.80361 4.99914 1363593 1446224_at 19 C2 chr19:36665196-36665583 19 C2 UGA Mm.61107 226098 Hectd2 HECT domain containing 2, mRNA (cDNA clone MGC:178371 IMAGE:9053363) acid-amino acid ligase activity;; intracellular;; ligase activity;; modification-dependent protein catabolic process;; protein modification process cell;; cell part cell part;; intracellular catalytic activity ligase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 54.9001 68.8915 56.6484 29.1738 25.6825 35.7090 0.0056087066 1.00047 5.90298 4.90251 1363599 1446230_at chr18:21346309-21346850 18 A2 IPA Mus musculus 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930418O04 product:unclassifiable, full insert sequence. 470.2001 485.9386 454.2227 90.1393 76.0707 99.0206 0.0012329286 2.41867 8.87634 6.45767 1363613 1446245_at chr2:52721981-52722503 2 C1.1 IPA Mus musculus 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030463N01 product:unknown EST, full insert sequence. 97.9039 83.4940 97.0095 22.3499 38.1765 32.4208 0.012829803 1.61376 6.53232 4.91855 1363652 1446284_at 15 D1 chr15:58871422-58871951 15 D1 UGA Mm.215481 211401 Mtss1 Metastasis suppressor 1, mRNA (cDNA clone IMAGE:5343395) actin binding;; actin filament organization;; actin filament polymerization;; cytoplasm;; cytoskeletal adaptor activity;; cytoskeleton;; filopodium assembly;; muscle organ development;; nervous system development;; SH3 domain binding;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding molecular adaptor activity;; protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process actin filament-based process;; anatomical structure development;; cell communication;; cell projection organization;; cellular component assembly;; cellular macromolecular complex subunit organization;; macromolecular complex subunit organization;; multicellular organismal development;; organelle organization;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process 680.0408 669.7630 722.5169 219.8846 322.6587 305.4064 0.01437126 1.30827 9.43129 8.12302 1363692 1446324_at 5 chr5:15445246-15445625 5 A2 UGA Mm.445336 Transcribed locus 219.3186 216.2710 234.0584 55.7863 89.3368 71.0276 0.01172493 1.65699 7.80144 6.14444 1363787 1446421_at 3 chr3:68407435-68407941 3 E1 UGA Mm.448005 Transcribed locus 522.8414 468.4297 519.3505 101.5126 89.1817 115.5708 0.00040537873 2.30855 8.97416 6.66561 1363841 1446475_at 14 chr14:120692309-120692809 14 E4 UG5 Mm.453644 Transcribed locus 66.3173 65.7148 77.2464 13.2299 21.4879 16.3409 0.0046651649 2.05975 6.12029 4.06053 1363875 1446509_at chr2:131342326-131342825 2 F1 IPA B130066H01Rik RIKEN cDNA B130066H01 gene 767.4668 821.5117 818.7366 144.4612 149.5121 178.7410 0.00061389231 2.35432 9.64778 7.29346 1363963 1446598_at 11 UGA Mm.441616 Transcribed locus 135.0681 139.0443 145.4135 57.0676 57.9317 74.0400 0.0077328444 1.15995 7.12699 5.96704 1363986 1446621_at 4 chr4:8740998-8741542 4 A1 UGA Mm.410534 Transcribed locus 216.2075 214.2630 185.3755 95.4112 100.2825 84.1238 0.00040367059 1.13845 7.67794 6.53948 1363991 1446626_at 16 B1|16 11.0 cM chr16:18321758-18322258 16 A3 UGA Mm.265990 27883 D16H22S680E DNA segment, Chr 16, human D22S680E, expressed (D16H22S680E), mRNA 288.3186 271.1169 286.9852 71.0462 90.3918 87.1506 0.0022182314 1.77496 8.13971 6.36475 1364275 1446921_at 11 chr11:11901351-11901733 11 A1 UGA Mm.438641 Transcribed locus 91.9000 98.3205 96.0602 31.8773 38.5551 46.3896 0.011848648 1.30942 6.57576 5.26634 1364301 1446947_at chr2:135743824-135744212 2 F3 IPA Unknown 560.5491 570.3365 560.1990 77.1344 78.8355 77.4250 3.3915162e-09 2.85712 9.13872 6.28160 1364367 1447016_at 5 chr5:64550855-64565499 5 C3.1 RSQ XM_001476849 1 1 100046817 LOC100046817 PREDICTED: hypothetical protein LOC100046817 (LOC100046817), mRNA. 93.2839 97.7725 87.8000 33.5884 40.8376 40.9829 0.0015115138 1.27746 6.53702 5.25956 1364419 1447071_at chr19:55849331-55849773 19 D2 IPA Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230007B16 product:unknown EST, full insert sequence. 51.0538 40.4049 38.6752 15.7512 17.0158 18.2765 0.0025797685 1.34188 5.42791 4.08604 1364442 1447096_at 1 UGA Mm.395135 Transcribed locus 169.0606 168.0111 179.1933 73.2563 80.9476 69.9972 0.00052185778 1.20539 7.42639 6.22101 1364822 1447526_at chr5:119054873-119055103 5 F IPA ESTs 106.9335 122.7080 111.0269 52.8367 59.8079 45.2108 0.003539699 1.11670 6.82481 5.70811 1364823 1447527_at chr8:47839851-47840054 8 B1.1 IPA ESTs 8708.4505 9096.3150 9183.7127 3522.4624 4182.4789 3367.7075 0.0036011473 1.29136 13.13471 11.84335 1372102 1447812_x_at 6 A3.3 UGA Mm.39046 68794 Flnc Strain C3H filamin Focal adhesion CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510];; MAPK signaling pathway actin binding;; actin cytoskeleton;; actin filament-based process;; cytoplasm;; cytoskeleton;; membrane;; muscle fiber development cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; non-membrane-bounded organelle binding protein binding cellular process;; developmental process;; multicellular organismal process actin filament-based process;; anatomical structure development;; cellular developmental process;; multicellular organismal development 3872.9896 3869.2951 3842.8185 680.4346 707.2991 497.9465 0.0036623631 2.63623 11.91501 9.27878 1364970 1447891_at IPA Unknown 127.2222 203.5696 128.8888 64.9612 65.0472 88.4698 0.022269522 1.05284 7.22352 6.17068 1372187 1447937_a_at 4 RSQ Mm.440578 NM_178649 15 15 108816 RP23-388P16.10 4933409K07Rik RIKEN cDNA 4933409K07 gene (4933409K07Rik), mRNA. 209.4228 196.3370 179.1335 86.7933 103.1029 85.0448 0.00085002609 1.09158 7.60412 6.51253 1365020 1448049_at 10 B5.1 UGA Mm.23846 108829 Jmjd1c Jumonji domain containing 1C, mRNA (cDNA clone IMAGE:3676222) chromatin modification;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 423.8846 443.0281 428.8158 200.0665 179.6936 168.1996 0.0020491131 1.24508 8.75433 7.50925 1372269 1453435_a_at 1 chr1:164804576-164805571 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 270.1845 275.2630 275.4620 71.8476 122.6409 84.6470 0.019764328 1.59321 8.09606 6.50285 1365603 1453512_at chr14:120797869-120798366 14 E4 IPA 5430437C10Rik RIKEN cDNA 5430437C10 gene 119.0483 133.2581 133.3976 61.5283 58.5704 55.2770 0.00011146441 1.13640 7.00436 5.86796 1365654 1453586_at 19 C3|19 35.5 cM chr19:40816546-40816931 19 C3 UGA Mm.2824 12495 Entpd1 Ectonucleoside triphosphate diphosphohydrolase 1, mRNA (cDNA clone MGC:18369 IMAGE:3674983) Purine metabolism;; Pyrimidine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] ATP binding;; ATP catabolic process;; basal lamina;; calcium ion binding;; G-protein coupled receptor protein signaling pathway;; hydrolase activity;; integral to membrane;; magnesium ion binding;; membrane;; nucleoside-diphosphatase activity;; nucleoside-triphosphatase activity;; nucleotide binding;; platelet activation;; purine ribonucleoside diphosphate catabolic process cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular matrix part;; extracellular region part;; membrane;; membrane part binding;; catalytic activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus catabolic process;; cell activation;; cell communication;; cellular metabolic process;; coagulation;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; response to external stimulus;; response to stress 85.5694 73.1617 90.1924 37.1552 42.8375 35.2929 0.00087025504 1.10979 6.36899 5.25920 1365728 1453688_at 9 A1 chr9:3412610-3413165 9 A1 UGA Mm.245482 244672 Cwf19l2 CWF19-like 2, cell cycle control (S. pombe), mRNA (cDNA clone MGC:159188 IMAGE:40130000) 89.0823 103.1829 102.7695 29.7178 35.8548 37.7594 0.00058697899 1.51776 6.61647 5.09870 1365738 1453698_at 4 UGA Mm.447147 Transcribed locus 203.0790 243.3040 240.4023 92.3646 118.5636 83.9307 0.0045977529 1.23064 7.83394 6.60330 1366017 1454141_at 10 chr10:69393723-69394253 10 B5.3 chr10:69393067-69394318 10 B5.3 RSQ XM_001474884 2 1 70557 5730416O20Rik PREDICTED: RIKEN cDNA 5730416O20 gene (5730416O20Rik), mRNA. 966.2950 961.9017 945.5457 406.4809 435.6952 369.5715 0.0025965571 1.24905 9.90369 8.65464 1366423 1454617_at 13 chr13:81034763-81035269 13 C3 chr13:81022682-81035303 13 C3 RSQ Mm.423137 NM_001042591 1 1 105171 Arrdc3 arrestin domain containing 3 (Arrdc3), mRNA. cytoplasm cell;; cell part cell part;; intracellular;; intracellular part 56.6816 47.6452 57.2635 28.0236 16.7551 28.4394 0.031722979 1.17790 5.74620 4.56831 1366492 1454768_at 12 chr12:17179290-17179470 12 A1.1 chr12:17178905-17183694 12 A1.1 RSQ Mm.40173 NM_201531 1 1 382571 Kcnf1 potassium voltage-gated channel, subfamily F, member 1 (Kcnf1), mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 1701.1270 1795.4319 1793.4260 872.0241 956.6963 779.1138 0.004036819 1.02502 10.78363 9.75861 1366859 1455399_at 4 chr4:133784017-133784469 4 D3 chr4:133783956-133794314 4 D3 RSQ Mm.331958 NM_001081047 1 1 194231 RP23-354H24.4 Cnksr1 connector enhancer of kinase suppressor of Ras 1 (Cnksr1), mRNA. cell cortex;; kinase activity;; protein binding, bridging;; Ras protein signal transduction;; Rho protein signal transduction cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity protein binding;; transferase activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 1476.9868 1386.8793 1457.6050 420.5623 399.5442 425.2883 1.355471e-06 1.79492 10.49182 8.69689 1366875 1455418_at 10 chr10:52993290-52993843 10 B3 UGA Mm.138292 Transcribed locus 461.7847 447.4748 444.7372 180.7945 231.4670 221.5834 0.0085713207 1.10299 8.81785 7.71486 1366899 1455455_at 3 chr3:85673879-85674282 3 F1 chr3:85673767-85691315 3 F1 RSQ Mm.119926 NM_177130 1 1 320302 Glt28d2 glycosyltransferase 28 domain containing 2 (Glt28d2), mRNA. Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; N-Glycan biosynthesis [PATH:mmu00510];; N-Glycan biosynthesis transferase activity catalytic activity transferase activity 323.3480 312.9609 330.9818 147.9682 111.6427 84.0424 0.021983894 1.53082 8.33246 6.80164 1367030 1455660_at 15 43.3 cM chr15:78180890-78181373 15 E1 chr15:78156419-78181431 15 E1 RSQ Mm.235324 NM_007780 1 1 12983 Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), mRNA. IL 3 signaling pathway Apoptosis;; Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] cytokine receptor activity;; cytokine-mediated signaling pathway;; integral to membrane;; membrane;; protein binding;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 725.0123 771.4184 778.8885 262.1185 351.4379 353.0913 0.0098371036 1.24780 9.56617 8.31837 1367085 1455744_at 17 UGA Mm.458985 Transcribed locus 818.7012 769.6025 721.9888 239.0936 236.5545 241.3855 0.00073991668 1.68611 9.58700 7.90089 1367261 1456139_at chr17:12960003-12960449 17 A1 IPA Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130073E08 product:unknown EST, full insert sequence. 315.2422 293.4688 313.1209 126.8402 137.4310 137.7956 2.5277584e-05 1.19738 8.26265 7.06527 1367275 1456160_at 11 UG5 Mm.455208 Transcribed locus 719.2288 725.2630 795.3966 130.1038 145.5268 176.3627 0.0011517525 2.31905 9.54273 7.22369 1372399 1456209_x_at 7 chr7:71051754-71051840 7 C UGA Mm.446212 Transcribed locus 151.2188 190.1222 188.1675 92.3481 84.1225 84.3209 0.0049947982 1.01530 7.45572 6.44042 1367377 1456347_at 17 UG5 Mm.453388 Transcribed locus 619.9110 631.0093 639.9392 226.2746 237.0717 232.4542 1.8289658e-06 1.44244 9.29974 7.85730 1367413 1456413_at 3 chr3:97569364-97569821 3 F2.2 UGA Mm.443527 Transcribed locus 469.0408 446.6519 423.1519 133.2176 200.8260 106.1008 0.023163345 1.65496 8.80054 7.14558 1367426 1456429_at 18 E1 chr18:65613817-65614305 18 E1 UGA Mm.132613 240354 Malt1 Mucosa associated lymphoid tissue lymphoma translocation gene 1, mRNA (cDNA clone MGC:124470 IMAGE:40048908) B cell receptor signaling pathway CLASS Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660] Cellular Processes; Immune System; B cell receptor signaling pathway [PATH:mmu04662];; T cell receptor signaling pathway apoptosis;; B cell activation;; B-1 B cell differentiation;; cysteine-type endopeptidase activity;; cytoplasm;; cytosol;; hydrolase activity;; I-kappaB kinase/NF-kappaB cascade;; innate immune response;; modification-dependent protein catabolic process;; nucleus;; peptidase activity;; positive regulation of NF-kappaB transcription factor activity;; positive regulation of T cell activation;; protein binding;; proteolysis;; regulation of apoptosis;; regulation of T cell receptor signaling pathway;; response to fungus;; response to molecule of bacterial origin;; T cell proliferation cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multi-organism process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; catabolic process;; cell activation;; cell communication;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; immune response;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress 1145.4934 1305.5997 1295.9852 402.7080 535.7531 502.0988 0.0024217882 1.38708 10.28403 8.89695 1367516 1456610_at 11 chr11:69213540-69214277 11 B3 chr11:69212009-69227177 11 B3 RSQ Mm.261201 NM_001017426 1 1 216850 RP23-5O23.5 Kdm6b KDM1 lysine (K)-specific demethylase 6B (Kdm6b), mRNA. chromatin modification;; histone demethylation;; inflammatory response;; iron ion binding;; metal ion binding;; negative regulation of transcription from RNA polymerase II promoter;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; sequence-specific DNA binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; response to stress 30.6956 36.6082 33.8353 12.5870 15.1332 13.3285 0.0002743909 1.30152 5.07150 3.76999 1367580 1456717_at chr7:119824852-119825087 7 F1 IPA ESTs 2969.6121 3010.1049 3136.9788 922.8981 834.6489 1035.6519 0.0015837865 1.71181 11.56894 9.85713 1367712 1456888_at 9 F2 chr9:108934151-108934674 9 F2 UGA Mm.132391 270198 Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 splice isoform 7 (Pfkfb4) mRNA, complete cds, alternatively spliced Fructose and mannose metabolism CLASS Metabolism; Carbohydrate Metabolism; Fructose and mannose metabolism [PATH:mmu00051] 6-phosphofructo-2-kinase activity;; ATP binding;; catalytic activity;; fructose 2,6-bisphosphate metabolic process;; fructose metabolic process;; fructose-2,6-bisphosphate 2-phosphatase activity;; hydrolase activity;; kinase activity;; metabolic process;; nucleotide binding;; transferase activity binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; transferase activity metabolic process alcohol metabolic process;; primary metabolic process 282.7037 293.1244 289.3290 77.6777 103.2862 89.6828 0.0043805128 1.68613 8.17169 6.48556 1367751 1456927_at 4 chr4:116008060-116008445 4 D1 UGA Mm.439252 Transcribed locus 33.2792 42.5394 32.1368 15.7227 16.2060 18.3566 0.0044320206 1.09399 5.15781 4.06382 1367794 1456973_at chr10:67568247-67568753 10 B5.1 IPA Mus musculus adult female vagina cDNA, RIKEN full-length enriched library, clone:9930108O06 product:hypothetical protein, full insert sequence. 589.1180 542.5408 599.7491 141.6304 163.0517 162.9297 6.2074994e-05 1.89031 9.17141 7.28109 1367806 1456986_at IPA Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430208D19 product:unknown EST, full insert sequence. 41.0669 66.6873 54.4917 9.9795 10.1156 9.1523 0.0050078501 2.44520 5.72907 3.28387 1367837 1457018_at 14 A3 chr14:24240872-24241001 14 A3 UGA Mm.343607 16531 Kcnma1 Calcium-activated potassium channel SLO1 mRNA, complete cds, alternatively spliced Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] adult walking behavior;; apical plasma membrane;; auditory receptor cell differentiation;; binding;; calcium ion binding;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; catalytic activity;; cell maturation;; circadian rhythm;; cytoplasmic part;; endoplasmic reticulum;; external side of plasma membrane;; eye blink reflex;; integral to membrane;; integral to membrane;; ion channel activity;; ion transport;; large conductance calcium-activated potassium channel activity;; large conductance calcium-activated potassium channel activity;; locomotor rhythm;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; micturition;; negative regulation of cell volume;; neuromuscular process controlling balance;; plasma membrane;; postsynaptic membrane;; potassium channel activity;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; protein homooligomerization;; regulation of action potential in neuron;; regulation of aldosterone metabolic process;; regulation of membrane potential;; regulation of membrane potential;; relaxation of vascular smooth muscle;; response to hypoxia;; saliva secretion;; sensory perception of sound;; sensory perception of sound;; smooth muscle contraction involved in micturition;; synaptic transmission;; terminal button;; transport;; vasodilation;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex;; organelle;; synapse;; synapse part apical part of cell;; cell part;; cell projection;; cell projection part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; postsynaptic membrane;; protein complex;; synapse part binding;; catalytic activity;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus;; rhythmic process adult behavior;; anatomical structure development;; behavior;; biosynthetic process;; cell communication;; cellular component assembly;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; circadian rhythm;; developmental maturation;; digestion;; establishment of localization;; hormone metabolic process;; macromolecular complex subunit organization;; multicellular organismal development;; negative regulation of biological process;; negative regulation of multicellular organismal process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress;; rhythmic behavior;; system process;; transport 287.3496 302.0509 280.0951 81.3939 131.3736 149.4576 0.0374361 1.30904 8.17836 6.86932 1367839 1457022_at chrX:80383845-80383937 X C1 IPA ESTs, Weakly similar to POL2_MOUSE Retrovirus-related POL polyprotein [Contains: Reverse transcriptase ; Endonuclease] [M.musculus] 75.5634 68.5554 79.1126 28.6597 25.7304 24.5257 8.0364161e-05 1.50069 6.21488 4.71419 1367851 1457035_at 1 chr1:175653611-175655251 1 H3 chr1:175653558-175671940 1 H3 RSQ Mm.440876 XM_980696 3 2 226691 AI607873 PREDICTED: expressed sequence AI607873 (AI607873), mRNA. 100.9343 92.6367 76.6541 38.0199 51.2851 32.6128 0.010868772 1.16485 6.48369 5.31884 1367921 1457110_at 19 chr19:34951033-34951536 19 C2 UG5 Mm.447503 Transcribed locus 324.6839 330.9758 337.8339 143.9106 161.8186 148.8891 0.00080094501 1.12943 8.37121 7.24179 1367984 1457177_at 9 chr9:68825877-68826363 9 C UGA Mm.451593 Transcribed locus 21.4545 23.2764 21.4221 10.3500 9.1473 8.8597 0.00040290366 1.22429 4.46168 3.23739 1368036 1457231_at chr12:75015913-75016340 12 C3 IPA ESTs 395.3050 342.7759 362.0721 41.6182 83.8391 42.3097 0.011886831 2.79216 8.51603 5.72387 1368114 1457324_at 4 UGA Mm.444175 Transcribed locus 165.6190 182.7630 173.7182 76.4429 80.5701 76.6290 8.1670879e-05 1.15929 7.44205 6.28277 1368128 1457338_at chr1:136729334-136729876 1 E4 IPA ESTs 710.9297 660.0291 684.7195 201.1853 210.2235 174.3493 0.00062554271 1.81511 9.41977 7.60467 1368145 1457356_at 17 chr17:12946045-12946480 17 A1 UGA Mm.411497 Transcribed locus 387.0921 359.7645 320.9852 128.9364 143.8182 150.0465 0.00024148154 1.33531 8.47127 7.13596 1368162 1457374_at 18 E1 chr18:65329357-65329745 18 E1 UGA Mm.98668 83814 Nedd4l Neural precursor cell expressed, developmentally down-regulated gene 4-like, mRNA (cDNA clone MGC:49433 IMAGE:3157137) Endocytosis CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144];; Ubiquitin mediated proteolysis acid-amino acid ligase activity;; cytoplasm;; intracellular;; ligase activity;; modification-dependent protein catabolic process;; negative regulation of sodium ion transport;; negative regulation of sodium ion transport;; protein binding;; protein modification process;; sodium channel inhibitor activity cell;; cell part cell part;; intracellular;; intracellular part auxiliary transport protein activity;; binding;; catalytic activity channel regulator activity;; ligase activity;; protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of localization;; transport 45.7494 44.0759 46.2488 20.7427 20.9428 22.7143 0.00019151786 1.08017 5.50298 4.42281 1368189 1457402_at 1 chr1:12735585-12736076 1 A3 UGA Mm.446978 Transcribed locus 41.9833 43.3216 44.0450 16.7000 22.5141 17.6065 0.010669911 1.19904 5.42989 4.23085 1372470 1457429_s_at 1 A3 chr1:15845414-15845595 1 A3 UG5 Mm.131665 226866 Gm106 Gene model 106, (NCBI), mRNA (cDNA clone MGC:182330 IMAGE:9056224) extracellular region;; immune response;; polysaccharide binding;; scavenger receptor activity extracellular region binding;; molecular transducer activity carbohydrate binding;; pattern binding;; signal transducer activity immune system process;; response to stimulus immune response 735.0825 736.7864 793.6734 317.4966 326.0545 248.4035 0.0052177661 1.35439 9.55976 8.20537 1368255 1457477_at 14 chr14:120728076-120728467 14 E4 UGA Mm.412819 Transcribed locus 314.3741 286.8186 328.9385 106.8774 152.7630 156.7890 0.014968836 1.17812 8.27400 7.09588 1368327 1457553_at chr2:6739802-6740289 2 A1 IPA Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630035A22 product:unknown EST, full insert sequence. 85.8866 86.7986 65.1586 25.9339 24.2638 28.8316 0.0017987956 1.58092 6.29662 4.71569 1368349 1457575_at 2 chr2:52734850-52735317 2 C1.1 UGA Mm.26187 Transcribed locus 62.6033 66.3902 71.1858 20.5309 21.0899 21.1488 0.0005415698 1.67129 6.05819 4.38690 1368397 1457637_at 15 chr15:93423954-93424139 15 E3 UGA Mm.447383 Transcribed locus 30.2738 34.9679 41.9520 16.0047 19.6150 15.3816 0.0042063069 1.06706 5.14621 4.07915 1372499 1457656_s_at 17 chr17:51896651-51896813 17 C UGA Mm.477120 Transcribed locus 104.4957 104.2635 84.3457 24.2642 27.3846 33.4477 0.0006504949 1.78992 6.60321 4.81329 1368500 1457770_at 14 D2 chr14:70711457-70711852 14 D2 UGA Mm.270647 213053 Slc39a14 Solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 3, mRNA ferrous iron transmembrane transporter activity;; integral to membrane;; ion transport;; iron ion transport;; membrane;; metal ion transmembrane transporter activity;; metal ion transport;; plasma membrane;; transport;; zinc ion binding;; zinc ion transmembrane transporter activity;; zinc ion transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 649.3225 637.4060 655.8977 218.0542 290.3186 322.8936 0.01758482 1.24375 9.33873 8.09498 1368639 1457924_at 3 chr3:60305173-60433670 3 D RSQ Mm.255723 NM_020007 2 2 56758 Mbnl1 muscleblind-like 1 (Drosophila) (Mbnl1), mRNA. cytoplasm;; metal ion binding;; mRNA splice site selection;; nucleic acid binding;; nucleus;; nucleus;; regulation of alternative nuclear mRNA splicing, via spliceosome;; RNA binding;; skeletal muscle tissue development;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; ribonucleoprotein complex biogenesis 75.0242 69.7699 84.1292 30.5466 29.0232 40.9510 0.0064198008 1.20015 6.24945 5.04930 1368775 1458068_at chr11:119483657-119484173 11 E2 IPA ESTs 367.4297 422.3186 434.0081 172.3751 206.1438 171.7630 0.00060993199 1.15463 8.66836 7.51373 1368782 1458075_at chr1:34077221-34077733 1 B IPA Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930079L03 product:unknown EST, full insert sequence. 204.1420 201.1247 183.2335 36.9569 48.9872 51.0452 0.0022858935 2.11570 7.61431 5.49860 1368796 1458089_at 17 chr17:28572812-28573322 17 A3.3 UGA Mm.445012 Transcribed locus 165.4297 130.0993 161.4034 51.3315 49.2795 41.5543 0.00035870612 1.68215 7.24269 5.56054 1368827 1458121_at chr6:21969486-21969886 6 A3.1 IPA ESTs 80.2085 93.2761 81.0174 47.0727 36.4613 39.6197 0.0023398031 1.05201 6.40309 5.35109 1368865 1458159_at chr19:16221151-16221548 19 A IPA ESTs 213.3292 205.3803 219.3551 33.9863 38.4372 39.5957 0.00013741165 2.51254 7.73207 5.21953 1368884 1458179_at chr17:12967927-12968457 17 A1 IPA ESTs 104.8685 151.4088 92.1797 30.7100 24.6927 28.2550 0.0046872247 2.03135 6.82704 4.79569 1368999 1458308_at 10 C1 chr10:79529116-79529307 10 C1 UG5 Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 1230.5408 1253.7421 1190.2159 410.5964 520.1011 417.5446 0.0043486049 1.45470 10.25804 8.80334 1369044 1458376_at 14 chr14:120740319-120740808 14 E4 UGA Mm.440488 Transcribed locus 255.0898 229.1534 238.5366 76.0075 79.1880 92.4345 0.00051105108 1.54915 7.91103 6.36188 1369075 1458409_at chr14:55370840-55371308 14 C3 IPA ESTs 64.2993 73.0743 76.9292 23.3472 25.7181 31.1733 0.001356331 1.42379 6.15449 4.73071 1369097 1458432_at 1 chr1:43511003-43511494 1 B UG5 Mm.447891 Transcribed locus 374.5250 329.3741 364.9433 138.6086 155.7949 156.4852 0.00010220189 1.24526 8.47468 7.22942 1369131 1458469_at chr16:52052604-52053123 16 B5 IPA ESTs 107.2877 92.9492 108.6090 35.7645 33.1240 32.6023 0.00020982383 1.60318 6.68224 5.07905 1369156 1458496_at 11 chr11:105800527-105800813 11 E1 UGA Mm.445046 Transcribed locus 121.6147 140.5148 100.9294 40.1653 40.7944 35.2240 0.0020763563 1.63376 6.90599 5.27222 1369248 1458588_at chr3:68352972-68353390 3 E1 IPA Unknown 348.1427 313.2501 373.6611 130.9001 141.9397 134.7686 0.00069192638 1.34150 8.42676 7.08527 1369275 1458616_at 4 chr4:40759193-40759642 4 A5 UGA Mm.448507 Transcribed locus 391.1069 419.9036 398.2173 113.1539 123.8218 126.5902 3.5816648e-05 1.73482 8.65425 6.91943 1369619 1458969_at chr8:11786297-11786741 8 A1.1 IPA ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 683.1283 722.5378 673.8883 380.7653 316.2834 341.1993 0.002329049 1.00567 9.43644 8.43077 1369653 1459003_at X A6-A7.1 chrX:54043834-54044264 X A5 UGA Mm.3126 14199 RP23-71G11.1 Fhl1 Four and a half LIM domains 1, mRNA (cDNA clone MGC:32284 IMAGE:5012394) cell differentiation;; cytoplasm;; metal ion binding;; multicellular organismal development;; nucleus;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding cellular process;; developmental process;; multicellular organismal process cellular developmental process;; multicellular organismal development 115.0192 101.7045 109.4645 54.3720 54.3224 52.8791 0.0015322101 1.01180 6.76276 5.75096 1369844 1459205_at chr7:88577467-88577894 7 D3 IPA ESTs 48.7064 58.8901 53.1473 18.6303 18.3104 19.4046 0.0012810554 1.50847 5.73931 4.23083 1369860 1459224_at chr12:113124905-113125375 12 F1 IPA Mus musculus 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732469E12 product:unclassifiable, full insert sequence. 718.2914 714.1891 689.8825 210.0495 265.0699 169.5384 0.010658023 1.74284 9.46626 7.72343 1369874 1459238_at chr10:53062351-53062774 10 B3 IPA ESTs 88.4939 83.0955 87.0105 40.9067 41.0060 39.5791 2.5007127e-05 1.08954 6.42911 5.33957 1370038 1459403_at 9 A3|9 5.0 cM chr9:21544899-21545228 9 A3 UGA Mm.3213 16835 Ldlr Low density lipoprotein receptor, mRNA (cDNA clone MGC:29127 IMAGE:5052599) FXR and LXR Regulation of Cholesterol Metabolism;; SREBP control of lipid synthesis Endocytosis CLASS Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] calcium ion binding;; cholesterol homeostasis;; cholesterol homeostasis;; cholesterol metabolic process;; cholesterol transport;; coated pit;; endocytosis;; endosome;; integral to membrane;; lipid metabolic process;; lipid transport;; lipoprotein catabolic process;; lipoprotein catabolic process;; lipoprotein metabolic process;; low-density lipoprotein binding;; low-density lipoprotein particle;; low-density lipoprotein receptor activity;; low-density lipoprotein receptor activity;; membrane;; protein binding;; receptor activity;; steroid metabolic process;; transport;; very-low-density lipoprotein receptor activity cell;; cell part;; extracellular region;; extracellular region part;; macromolecular complex;; organelle cell part;; endomembrane system;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; plasma lipoprotein particle;; protein-lipid complex binding;; molecular transducer activity ion binding;; protein binding;; signal transducer activity biological regulation;; cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process alcohol metabolic process;; biosynthetic process;; catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; membrane organization;; primary metabolic process;; regulation of biological quality;; transport;; vesicle-mediated transport 366.7719 358.6909 391.7159 81.8156 94.4264 83.4715 5.5560204e-05 2.10679 8.53967 6.43288 1370044 1459409_at chr10:59030775-59031053 10 B4 IPA Mus musculus adult male cecum cDNA, RIKEN full-length enriched library, clone:9130014A12 product:unclassifiable, full insert sequence. 73.2407 96.3366 95.0563 35.4571 33.8204 35.0140 0.0079745297 1.33254 6.45177 5.11923 1370101 1459467_at chr14:25054971-25055453 14 A3 IPA ESTs 129.3122 96.7926 116.4645 34.2207 31.0515 38.7872 0.00052754299 1.71480 6.82509 5.11030 1370104 1459470_at chr16:92615772-92616302 16 C4 IPA ESTs 730.4230 720.9127 704.2392 104.2297 176.7560 163.6361 0.01014073 2.31420 9.48873 7.17453 1370187 1459557_at chr9:48515954-48516379 9 A5.3 IPA ESTs 89.3458 99.2999 100.0732 30.8986 34.5226 34.6296 3.5381755e-05 1.52903 6.58665 5.05762 1370236 1459609_at chr8:79928865-79929131 8 C1 IPA Unknown 127.6944 125.5922 127.5473 27.6067 63.1479 43.9594 0.044602156 1.57944 6.98801 5.40857 1370262 1459635_at IPA ESTs 445.9494 429.3697 442.6923 217.2989 175.3499 159.4258 0.0097965933 1.26753 8.77899 7.51146 1372645 1459843_s_at 8 C2 chr8:81862347-81862401 8 C2 UGA Mm.223717 17125 Smad1 MAD homolog 1 (Drosophila) (Smad1), mRNA CTCF: First Multivalent Nuclear Factor TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] BMP signaling pathway;; BMP signaling pathway;; BMP signaling pathway;; cytoplasm;; gamete generation;; hindbrain development;; homeostatic process;; inflammatory response;; intracellular;; MAPKKK cascade;; mesodermal cell fate commitment;; midbrain development;; negative regulation of cell proliferation;; nucleus;; osteoblast fate commitment;; positive regulation of gene expression;; positive regulation of osteoblast differentiation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; RNA polymerase II transcription factor activity;; transcription;; transcription factor activity;; transcription factor complex;; transforming growth factor beta receptor signaling pathway cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; nitrogen compound metabolic process;; ossification;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive process;; response to external stimulus;; response to stress;; sexual reproduction;; tissue remodeling 140.1012 138.0767 143.4757 53.6794 70.7306 63.9552 0.0087096248 1.17159 7.13477 5.96318 1370597 1460147_at chr13:110432934-110433349 13 D2.2 IPA A730009E18Rik RIKEN cDNA A730009E18 gene