A 1 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen A 2 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen A 3 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen A 4 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen A 5 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen A 6 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen B 7 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen B 8 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen B 9 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen B 10 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen B 11 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen B 12 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen C 13 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen C 14 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen C 15 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen C 16 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen C 17 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen C 18 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Gene Property Filtering 18 arrays and 45101 genes in the input dataset 18 arrays and 417 genes in the output dataset. 44684 genes excluded for Well ID not being in local list 'EG3-1-test-3+FC'. A A A A A A B B B B B B C C C C C C 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 28.1041 27.7516 34.3424 31.0589 37.5179 31.8889 801.1414 853.2240 771.4070 823.4967 850.5619 793.6926 258.9766 312.4832 296.8349 313.8703 278.6790 216.3908 1350144 AFFX-DapX-M_at IPA B. subtilis GEN=dapB, jojF DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2020-2580 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA- 18.3789 17.7176 21.8985 25.1611 21.4544 22.7668 1230.4274 1235.7222 1123.3146 1135.9661 1185.5707 1146.4961 276.9004 299.9979 301.1684 313.7877 282.7195 231.2158 1350142 AFFX-DapX-3_at IPA B. subtilis GEN=jojG DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2684-3130 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carbox 21.1308 22.2289 21.3380 27.6863 24.9365 24.0655 75.5921 75.6916 94.0622 72.1614 79.0074 73.1738 30.4225 42.6698 38.3770 38.5685 30.1528 32.0137 1350147 AFFX-LysX-M_at IPA B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 720-990 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). 33.3421 42.4036 38.2040 35.7604 44.1094 36.5224 235.9080 284.5286 252.8868 250.6604 290.8588 257.3694 74.2549 85.4592 91.2351 93.6724 78.6248 77.9344 1350145 AFFX-LysX-3_at IPA B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 1061-1343 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). 31.3530 34.6326 32.7602 38.3716 42.1984 38.6062 591.8521 591.8204 600.1130 609.5262 623.2756 592.6165 171.3071 198.3072 187.2436 198.0631 173.2261 160.0656 1350152 AFFX-ThrX-3_at IPA B. subtilis GEN=thrB DB_XREF=gb:X04603.1 NOTE=SIF corresponding to nucleotides 1689-2151 of gb:X04603.1 DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively). 8.8719 11.8089 9.6172 10.1152 10.5863 9.6172 758.4699 829.4598 695.4387 754.7926 767.0330 765.6097 205.4040 261.3741 236.2226 289.8911 234.9433 167.2898 1350164 AFFX-r2-Bs-dap-M_at IPA 11.5828 11.8164 12.5494 12.3145 16.4948 13.5418 1618.9296 1732.5477 1426.4386 1566.0153 1701.7583 1615.3336 381.6481 426.0964 441.1519 458.7377 358.8226 318.0669 1350162 AFFX-r2-Bs-dap-3_at IPA 9.5634 9.5076 10.2770 8.9902 9.5043 9.3156 56.7597 74.1617 82.9066 67.0102 88.6926 56.7824 23.5507 26.1362 27.2546 32.6149 21.5164 25.0545 1350166 AFFX-r2-Bs-lys-5_at IPA 13.7923 13.7775 13.8842 13.8032 14.8877 14.8192 80.6100 87.4554 78.7199 89.9643 89.5790 109.7782 22.6137 24.2998 22.7872 27.5300 23.6938 21.8166 1350167 AFFX-r2-Bs-lys-M_at IPA 25.1351 30.2504 24.4872 25.5294 25.2252 22.7726 108.1203 149.7591 83.7607 88.9093 123.4531 103.2695 37.5249 37.8194 41.1492 35.2576 35.3252 34.8098 1350165 AFFX-r2-Bs-lys-3_at IPA 16.9902 23.1943 22.5806 21.2359 16.7067 20.7162 125.8205 112.5800 99.0757 105.2021 119.9266 114.1218 32.0442 30.2141 48.9383 44.7214 39.4096 36.0316 1350170 AFFX-r2-Bs-phe-M_at IPA 89.4776 100.4149 88.0798 148.1886 130.8282 95.9337 255.7814 445.3617 297.7630 305.2630 330.4077 277.4852 101.2442 125.0812 150.8846 150.3424 116.6973 87.3953 1350168 AFFX-r2-Bs-phe-3_at IPA 28.5929 35.6742 21.3373 44.4092 29.3172 28.3437 677.5051 711.9807 644.7265 687.9365 688.4113 650.3661 190.9367 216.9596 201.0347 202.5408 211.5588 178.5492 1350180 AFFX-r2-Bs-thr-3_s_at IPA 2307.7538 2397.5171 3920.3912 2800.9538 2373.7481 3220.2609 3016.4046 3036.3917 2828.9401 3004.4966 2964.8620 3054.2322 998.1993 1552.2703 1420.2196 1332.5964 1340.1888 1336.4467 1350161 AFFX-MURINE_b1_at IPA M. musculus GEN=b1 DB_XREF=gb:U01310.1 NOTE=SIF corresponding to nucleotides 5-75 of gb:U01310.1 DEF=Mus musculus C57 Black6 BC1 scRNA. 98.2371 76.3803 108.2221 55.0766 110.4375 99.4734 3293.2630 3434.5666 5396.0694 6217.8418 3301.5602 6334.4440 3439.9127 3280.8623 2312.6162 3305.3953 2691.8335 2132.9520 1327781 1416041_at 10 chr10:21719153-21719585 10 A3 chr10:21705909-21719699 10 A3 RSQ NM_001161848 6 1 20393 Sgk1 serum/glucocorticoid regulated kinase 1 (Sgk1), transcript variant 3, mRNA. apoptosis;; ATP binding;; cellular response to insulin stimulus;; cytoplasm;; endoplasmic reticulum;; kinase activity;; nucleotide binding;; nucleus;; positive regulation of sodium ion transport;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; regulation of protein localization;; response to DNA damage stimulus;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity biological regulation;; cellular process;; death;; establishment of localization;; localization;; metabolic process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell death;; cellular metabolic process;; cellular response to stimulus;; establishment of localization;; macromolecule localization;; macromolecule metabolic process;; positive regulation of biological process;; positive regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of localization;; response to chemical stimulus;; response to endogenous stimulus;; response to stress;; transport 249.2729 157.6374 254.3201 263.0380 293.8712 270.9972 3446.3923 3507.7425 3740.2317 3792.1841 3435.3537 3776.1069 1193.3719 791.9517 1586.0958 738.2315 711.9717 643.7601 1327844 1416125_at 17 13.0 cM chr17:28536264-28536617 17 A3.3 chr17:28536039-28623057 17 A3.3 RSQ Mm.276405 NM_010220 1 1 14229 Fkbp5 FK506 binding protein 5 (Fkbp5), mRNA. binding;; cytoplasm;; isomerase activity;; nucleus;; peptidyl-prolyl cis-trans isomerase activity;; protein binding;; protein folding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 56.2150 94.8643 105.1989 84.7659 184.6320 87.7382 1102.7307 1105.3054 1302.4297 1301.1519 1109.2005 1293.8646 637.1139 391.6131 424.6579 376.9413 413.3499 389.1086 1327847 1416129_at 4 chr4:150242409-150242794 4 E2 chr4:150229199-150242989 4 E2 RSQ Mm.318841 NM_133753 1 1 74155 RP23-272N19.4 Errfi1 ERBB receptor feedback inhibitor 1 (Errfi1), mRNA. cytoplasm;; cytosol;; protein binding;; receptor activity;; stress-activated protein kinase signaling pathway cell;; cell part cell part;; intracellular;; intracellular part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular response to stimulus;; regulation of biological process;; regulation of cellular process;; response to stress 120.5971 155.6736 150.1349 347.2172 257.0916 272.5061 2725.9996 2806.0964 802.0430 734.4321 2673.9977 702.4433 234.9824 228.5365 290.1378 416.5916 379.8765 532.6616 1328194 1416576_at 11 chr11:117827755-117827967 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 60.0895 89.6449 61.6450 66.4106 61.3588 49.9231 407.9903 406.7446 942.3607 894.1517 386.8004 921.0368 436.3086 403.7933 481.0253 406.5774 395.0082 303.9622 1343360 1416708_a_at 7 13.0 cM chr7:31915193-31917633 7 B1 chr7:31915145-31936069 7 B1 RSQ Mm.27366 NM_027898 1 1 52857 Gramd1a GRAM domain containing 1A (Gramd1a), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 186.9819 208.8272 226.0408 67.4182 76.5623 92.6209 306.4065 322.0408 462.7434 452.3175 295.9960 474.3021 225.1327 200.4297 210.4280 227.3950 208.7630 166.9852 1328472 1416926_at 4 chr4:11101005-11101491 4 A1 chr4:11083587-11101524 4 A1 RSQ Mm.393018 NM_021897 1 1 60599 RP23-343F17.4 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Trp53inp1), mRNA. apoptosis;; cell cycle arrest;; cytoplasm;; induction of apoptosis;; nucleolus;; nucleus;; response to stress cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part biological regulation;; cellular process;; death;; developmental process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cell death;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 80.8871 81.4828 88.1039 51.3594 71.3484 58.0377 122.5754 111.0137 131.4061 153.2983 116.6809 142.1691 67.3876 63.6202 66.7147 58.8522 64.5508 74.0233 1328473 1416927_at 4 chr4:11098069-11098628 4 A1 chr4:11083587-11101524 4 A1 RSQ Mm.393018 NM_021897 1 1 60599 RP23-343F17.4 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Trp53inp1), mRNA. apoptosis;; cell cycle arrest;; cytoplasm;; induction of apoptosis;; nucleolus;; nucleus;; response to stress cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part biological regulation;; cellular process;; death;; developmental process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cell death;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 36.8078 37.7977 51.7841 35.3074 31.7007 32.4434 583.9152 592.9832 1023.5599 1065.2307 582.7594 1082.9604 316.0087 330.1832 538.1445 305.2283 334.1036 276.5211 1328519 1416981_at 3 22.5 cM chr3:52149839-52150299 3 C chr3:52072258-52154031 3 C RSQ Mm.29891 NM_019739 1 1 56458 Foxo1 forkhead box O1 (Foxo1), mRNA. AKT Signaling Pathway Insulin signaling pathway;; Pathways in cancer;; Prostate cancer CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Prostate cancer [PATH:mmu05215] blood vessel development;; cytoplasm;; DNA binding;; insulin receptor signaling pathway;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to endogenous stimulus 129.6932 138.2288 117.5082 151.9346 121.5914 152.5806 464.1641 445.9191 886.9903 782.5951 421.0049 793.7942 375.3186 315.7809 522.0165 314.1365 341.1380 281.8085 1328520 1416982_at 3 22.5 cM chr3:52152874-52153321 3 C chr3:52072258-52154031 3 C RSQ Mm.29891 NM_019739 1 1 56458 Foxo1 forkhead box O1 (Foxo1), mRNA. AKT Signaling Pathway Insulin signaling pathway;; Pathways in cancer;; Prostate cancer CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Prostate cancer [PATH:mmu05215] blood vessel development;; cytoplasm;; DNA binding;; insulin receptor signaling pathway;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to endogenous stimulus 60.6083 59.9982 60.9835 53.9272 69.9326 53.1709 694.7075 689.8186 1050.2357 1161.9311 680.7294 1276.5964 368.5408 347.8397 484.8291 292.9109 344.5294 265.9390 1343415 1416983_s_at 3 chr3:52153576-52154004 3 C UG5 Mm.395558 Transcribed locus 39.1482 36.8476 42.2177 28.7601 31.5657 30.6060 124.0008 114.1493 68.3060 96.8862 127.4615 96.6891 39.8209 34.8730 50.1756 46.8627 41.6515 40.4314 1328931 1417483_at 16 chr16:55811560-55812070 16 C1.1 chr16:55811489-55838754 16 C1.1 RSQ NM_001159395 3 1 80859 Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 3, mRNA. inflammatory response;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; response to stress 289.4058 124.5075 266.2746 278.4891 188.0248 364.8280 343.9688 333.7577 491.9685 443.1550 323.3741 480.8783 198.0915 196.9632 222.7773 271.4497 57.5653 295.0876 1329033 1417600_at 16 chr16:36750284-36750836 16 B3 chr16:36750249-36785048 16 B3 RSQ Mm.281804 NM_021301 1 1 57738 Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 (Slc15a2), transcript variant 1, mRNA. high affinity oligopeptide transporter activity;; integral to membrane;; integral to plasma membrane;; membrane;; membrane fraction;; oligopeptide transport;; oligopeptide transporter activity;; peptide transport;; protein transport;; symporter activity;; transport;; transporter activity cell;; cell part cell fraction;; cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 2460.2531 1814.4834 2146.0429 1643.7306 1142.0653 1974.7052 136.6527 142.6062 185.4859 161.3036 132.5847 161.7408 53.7779 51.4322 60.4345 45.3365 61.4561 64.2081 1329204 1417821_at 17 B1|17 19.0 cM chr17:35134509-35134926 17 B1 UG5 Mm.22506 110956 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942) viral envelope virion;; virion part viral envelope;; virion part 3011.6942 2313.2775 2469.4441 2068.6982 1249.0464 2228.4049 237.5964 232.3563 245.9297 260.7433 231.2765 265.4801 101.8506 141.9652 129.9855 99.3466 112.8484 122.2624 1329205 1417822_at 17 B1|17 19.0 cM chr17:35133679-35134254 17 B1 UGA Mm.22506 110956 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942) viral envelope virion;; virion part viral envelope;; virion part 164.1750 133.5957 190.0678 127.4434 176.0916 175.2583 246.7763 268.5551 630.5303 733.3004 233.2480 756.2393 131.8816 143.0271 185.3942 120.0337 121.7201 127.7511 1329298 1417929_at 14 chr14:55341124-55341626 14 C3 chr14:55341051-55400723 14 C3 RSQ Mm.276831 NM_016972 1 1 50934 Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), mRNA. amine transmembrane transporter activity;; amino acid transmembrane transporter activity;; amino acid transport;; cytoplasm;; integral to membrane;; L-amino acid transmembrane transporter activity;; L-amino acid transport;; membrane;; plasma membrane;; transport cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 123.9141 89.5755 141.4531 137.2241 133.4754 171.6132 479.3928 499.7630 518.4976 537.2075 501.5408 491.2858 208.1934 239.0579 231.8742 237.5233 304.9657 267.9795 1329370 1418018_at 11 46.0 cM chr11:76595516-76598574 11 B5 chr11:76590709-76660510 11 B5 RSQ Mm.276736 NM_007754 2 2 12874 RP23-396O3.1 Cpd carboxypeptidase D (Cpd), mRNA. carboxypeptidase activity;; hydrolase activity;; integral to membrane;; membrane;; metal ion binding;; metallocarboxypeptidase activity;; metallopeptidase activity;; peptidase activity;; proteolysis;; serine-type carboxypeptidase activity;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity hydrolase activity;; ion binding metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 50.8392 50.2213 71.8814 57.9647 63.5955 56.6146 243.0805 216.2775 550.9603 512.3839 222.4566 535.1430 247.4181 210.7387 268.4159 190.8733 185.4139 196.6382 1329435 1418091_at 1 chr1:120581186-120581654 1 E2.3 chr1:120524521-120581745 1 E2.3 RSQ Mm.24621 NM_023755 1 1 81879 Tcfcp2l1 transcription factor CP2-like 1 (Tcfcp2l1), mRNA. cell morphogenesis;; cytoplasm;; cytoplasm organization;; determination of adult life span;; DNA binding;; epithelial cell maturation;; general transcriptional repressor activity;; membrane;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; positive regulation of growth;; regulation of transcription, DNA-dependent;; salivary gland development;; transcription;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; transcription repressor activity biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process aging;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; cytoplasm organization;; determination of adult life span;; developmental maturation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of growth;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process 33.2593 42.2277 34.6474 29.1846 33.4006 33.7862 424.5262 392.7871 427.7633 435.7528 384.7675 410.1836 166.7667 204.1521 170.5035 201.4742 199.2366 175.0066 1343611 1418094_s_at 11 chr11:84778338-84779387 11 C chr11:84771255-84779556 11 C RSQ Mm.1641 NM_007607 1 1 12351 RP23-167D6.1 Car4 carbonic anhydrase 4 (Car4), mRNA. Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] anchored to membrane;; carbonate dehydratase activity;; lyase activity;; membrane;; metal ion binding;; one-carbon metabolic process;; plasma membrane;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 49.0195 54.0427 60.0781 60.6264 68.8209 41.8306 176.0408 202.6519 230.0479 195.4947 200.3741 203.1519 103.4615 83.0247 96.7651 122.9946 96.6339 94.2549 1329468 1418133_at 7 A3|7 6.5 cM chr7:20393860-20394209 7 A3 UG5 Mm.439658 12051 Bcl3 B-cell leukemia/lymphoma 3 (Bcl3), mRNA antimicrobial humoral response;; defense response to bacterium;; defense response to protozoan;; DNA binding;; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;; extracellular matrix organization;; follicular dendritic cell differentiation;; germinal center formation;; humoral immune response mediated by circulating immunoglobulin;; marginal zone B cell differentiation;; negative regulation of apoptosis;; negative regulation of apoptosis;; negative regulation of tumor necrosis factor biosynthetic process;; nucleus;; positive regulation of interferon-gamma production;; positive regulation of interleukin-10 biosynthetic process;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription, DNA-dependent;; spleen development;; T-helper 1 type immune response;; T-helper 2 cell differentiation;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell communication;; cell death;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; cytokine production;; extracellular structure organization;; immune effector process;; immune response;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to biotic stimulus;; response to other organism;; response to stress 77.9668 77.4576 86.9542 82.0591 97.5000 61.4340 1616.0867 1573.0423 400.5288 415.3885 1580.4144 399.0308 170.6553 220.1440 217.9486 192.9692 173.9628 200.9535 1329642 1418349_at 18 15.0 cM chr18:36664709-36665151 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 80.9814 68.5231 82.1664 67.0932 81.9781 92.3880 4203.5671 4298.9217 1087.2290 1016.1770 4240.6475 1001.6325 229.5814 352.9350 339.5979 314.8332 306.3186 352.1650 1329643 1418350_at 18 15.0 cM chr18:36665688-36667226 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 790.8147 719.7172 1080.7113 565.1218 621.2118 822.4781 1804.0255 1845.1241 1720.5622 1620.5964 1839.5408 1608.2665 348.9983 559.5430 674.1314 435.9297 753.0758 824.2191 1329744 1418469_at 16 C3.1 chr16:76290241-76290637 16 C3.1 UGA Mm.455873 268903 Nrip1 Receptor interacting protein 140 histone deacetylase binding;; histone deacetylase complex;; lipid storage;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; ovarian follicle rupture;; ovulation;; protein binding;; receptor activity;; receptor binding;; regulation of transcription, DNA-dependent;; retinoid X receptor binding;; transcription;; transcription corepressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity protein binding;; signal transducer activity;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; biosynthetic process;; cellular metabolic process;; gamete generation;; macromolecule localization;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 138.6037 120.0857 85.5747 145.1529 229.5423 138.6037 7872.5805 7377.3226 8486.7441 8234.3186 7551.7015 8334.2463 4128.7749 3842.1831 4311.7755 3809.7594 3986.0059 3791.3741 1329836 1418595_at 17 chr17:56240045-56240601 17 D chr17:56240013-56249225 17 D RSQ Mm.476969 NM_020568 1 1 57435 S3-12 plasma membrane associated protein, S3-12 (S3-12), mRNA. cytoplasm;; lipid particle;; membrane;; plasma membrane cell;; cell part cell part;; intracellular;; intracellular part;; membrane 12.5075 14.0789 17.2431 16.4023 15.0032 16.8121 551.4382 590.7990 583.7400 589.9493 561.2075 562.3837 220.9147 195.1858 237.3959 204.8350 209.3547 194.5793 1329909 1418674_at 15 4.6 cM chr15:6763697-6764043 15 A1 chr15:6763576-6824313 15 A1 RSQ Mm.10760 NM_011019 1 1 18414 Osmr oncostatin M receptor (Osmr), mRNA. Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] cell surface receptor linked signal transduction;; cytokine receptor activity;; integral to membrane;; integral to plasma membrane;; membrane;; oncostatin-M receptor activity;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 136.3974 264.0459 165.5865 151.9182 263.3904 217.5748 83.0367 88.4326 164.2244 143.9866 105.5663 143.1606 82.8159 66.4872 73.7540 66.0142 70.1966 86.7123 1329953 1418722_at 9 chr9:110324928-110325482 9 F2 chr9:110322311-110325516 9 F2 RSQ Mm.236225 NM_008694 1 1 18054 Ngp neutrophilic granule protein (Ngp), mRNA. cytoplasmic vesicle;; defense response to bacterium cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; vesicle multi-organism process;; response to stimulus response to biotic stimulus;; response to other organism;; response to stress 56.0048 47.1434 51.9753 55.5420 67.2311 64.7609 1466.3991 1503.8276 1520.8179 1569.7753 1546.8469 1507.4704 748.8586 587.7075 972.1469 658.2704 845.0681 552.6684 1330123 1418932_at 13 32.0 cM chr13:53062781-53063171 13 B1 chr13:53062577-53076408 13 B1 RSQ Mm.136604 NM_017373 2 2 18030 Nfil3 nuclear factor, interleukin 3, regulated (Nfil3), mRNA. DNA binding;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; rhythmic process;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; rhythmic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 97.8678 115.3756 157.4894 123.0161 114.2059 122.1776 457.4114 434.6008 388.5028 421.8766 431.5846 406.3183 180.9722 179.6729 218.4654 174.8988 260.6096 214.0515 1330208 1419034_at 2 chr2:152104805-152104961 2 G3 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 2 2 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 53.7112 61.4677 104.4402 66.7338 60.0215 90.4269 373.5052 367.8563 366.5053 363.7908 349.7863 338.3349 170.1959 172.9852 180.6407 158.0714 248.3708 224.7460 1343779 1419035_s_at 2 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 3 3 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 1111.0561 972.0292 1408.2843 831.0147 716.8789 1167.3100 1095.4388 1178.2450 1285.4907 1195.2479 1184.1399 1176.4773 254.4146 504.5371 539.1170 376.9467 638.1368 680.1445 1343780 1419038_a_at 2 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 2 2 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 22.5446 28.0094 18.1448 21.1269 24.5876 22.0562 38.3423 33.7087 56.4478 58.8460 40.9233 59.5199 19.3669 24.2580 22.2728 20.2734 22.2457 22.1620 1343786 1419075_s_at 7 B4|7 23.5 cM UG5 Mm.200941 20209 Saa2 Serum amyloid A 2, mRNA (cDNA clone MGC:18481 IMAGE:3662957) acute-phase response;; extracellular region;; high-density lipoprotein particle;; protein binding extracellular region;; extracellular region part;; macromolecular complex extracellular region part;; extracellular space;; plasma lipoprotein particle;; protein-lipid complex binding protein binding response to stimulus response to external stimulus;; response to stress 67.3386 71.9614 48.4715 57.0701 86.8489 77.5607 529.6322 541.6388 810.9575 769.8051 492.9852 836.9423 283.6139 377.9120 319.7924 236.2562 259.8741 327.5539 1330251 1419088_at 10 C1|10 C1-D1|10 47.0 c chr10:85808696-85809146 10 C1 UG5 Mm.4871 21859 Timp3 Tissue inhibitor of metalloproteinase 3, mRNA (cDNA clone MGC:25359 IMAGE:4239015) Inhibition of Matrix Metalloproteinases;; p53 Signaling Pathway basement membrane;; enzyme inhibitor activity;; extracellular region;; metalloendopeptidase inhibitor activity;; proteinaceous extracellular matrix extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part enzyme regulator activity enzyme inhibitor activity;; metalloenzyme regulator activity 22.2300 23.0892 23.0929 27.6047 38.9904 18.9183 48.8764 55.4908 61.7159 61.2972 63.7484 76.0614 21.2368 24.5026 25.2993 21.5839 20.7693 22.9311 1330349 1419209_at 5 51.0 cM chr5:91321568-91321979 5 E1 chr5:91320270-91322147 5 E1 RSQ Mm.21013 NM_008176 1 1 14825 Cxcl1 chemokine (C-X-C motif) ligand 1 (Cxcl1), mRNA. Chemokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062];; Cytokine-cytokine receptor interaction chemokine activity;; cytokine activity;; extracellular region;; extracellular space;; growth factor activity;; immune response;; inflammatory response extracellular region;; extracellular region part extracellular region part;; extracellular space binding protein binding immune system process;; response to stimulus immune response;; response to external stimulus;; response to stress 127.7439 190.8578 128.1612 138.5402 132.5525 120.1342 7353.9914 7360.2075 2638.8732 2549.1249 7427.3301 2603.0837 1057.5133 1109.7197 1362.5183 1067.1625 1922.5705 1670.4169 1330359 1419220_at 9 F4 chr9:119923004-119923392 9 F4 UGA Mm.10117 22437 Xirp1 Xin actin binding;; actin cytoskeleton organization;; cardiac muscle cell development;; cell junction;; cell-cell adherens junction;; fascia adherens;; filamin-C binding;; heart morphogenesis;; intercalated disc;; negative regulation of cell proliferation;; protein binding;; regulation of membrane potential;; sarcomere organization cell;; cell part cell part;; membrane;; membrane part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular homeostasis;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of biological quality;; regulation of cellular process 201.7551 254.9200 200.2951 184.1725 252.1916 206.6214 556.0256 580.7698 642.7993 617.3973 583.7638 674.2243 258.9297 414.8329 306.5692 238.1519 247.4853 351.9975 1330384 1419255_at 11 13.0 cM chr11:30007644-30008198 11 A3.3 chr11:30006842-30098257 11 A3.3 RSQ Mm.123110 NM_009260 1 1 20742 RP23-189P1.1 Spnb2 spectrin beta 2 (Spnb2), transcript variant 2, mRNA. Tight junction CLASS Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] actin binding;; actin filament capping;; calmodulin binding;; common-partner SMAD protein phosphorylation;; cortical cytoskeleton;; cytoplasm;; cytoskeleton;; membrane;; nucleus;; plasma membrane;; protein binding;; SMAD protein nuclear translocation;; spectrin;; structural constituent of cytoskeleton cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; structural molecule activity protein binding;; structural constituent of cytoskeleton anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cellular component assembly;; cellular component disassembly;; cellular localization;; cellular macromolecular complex subunit organization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecular complex subunit organization;; macromolecule localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of cellular component biogenesis;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; transport 66.5088 64.7142 53.7944 70.2225 105.8798 96.2769 1425.9557 1448.8141 1440.1093 1367.0532 1350.6612 1358.8526 583.2655 522.9783 471.7414 440.3720 655.3326 685.5480 1330421 1419301_at 7 44.5 cM chr7:96557344-96557739 7 E1 chr7:96552875-96558620 7 E1 RSQ Mm.86755 NM_008055 1 1 14366 Fzd4 frizzled homolog 4 (Drosophila) (Fzd4), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Endocrine System; Melanogenesis [PATH:mmu04916] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210] Human Diseases; Cancers; Basal cell carcinom;; Colorectal cancer;; Melanogenesis;; Pathways in cancer;; Wnt signaling pathway cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; protein binding;; receptor activity;; signal transducer activity;; signal transduction;; transmembrane receptor activity;; Wnt receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 117.7145 393.3468 78.6809 269.7274 367.4791 305.5416 296.1956 264.9176 534.1462 515.8767 258.2057 521.3794 24.1276 26.9098 61.2412 61.7332 50.4948 41.1376 1343853 1419394_s_at 3 43.6 cM chr3:90473446-90473926 3 F1 chr3:90472992-90473956 3 F1 RSQ Mm.21567 NM_013650 1 1 20201 S100a8 S100 calcium binding protein A8 (calgranulin A) (S100a8), mRNA. calcium ion binding;; chemotaxis binding ion binding locomotion;; response to stimulus behavior;; response to chemical stimulus;; response to external stimulus;; taxis 156.7537 162.1447 188.7075 157.5876 186.2595 182.1519 4731.8353 4969.4579 4102.5894 3903.8400 4805.7908 3935.7060 1541.0546 1934.3094 1800.4696 2898.5409 3190.1769 1298.0798 1330677 1419621_at 19 chr19:42116522-42119434 19 C3 chr19:42110527-42119600 19 C3 RSQ Mm.143737 NM_020033 1 1 56642 Ankrd2 ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA. I band;; nucleus;; sarcomere cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 51.4218 46.6734 59.2257 77.4440 93.1641 59.0387 214.5170 225.2440 270.4297 272.6499 192.5408 267.0964 67.8707 89.4319 81.1819 79.0585 64.8317 79.5374 1343918 1419700_a_at 5 chr5:44384916-44385436 5 B3 chr5:44384860-44492920 5 B3 RSQ Mm.6250 NM_008935 1 1 19126 Prom1 prominin 1 (Prom1), mRNA. apical plasma membrane;; brush border;; cell projection;; cell surface;; extracellular space;; integral to membrane;; integral to plasma membrane;; membrane;; microvillus;; plasma membrane;; stereocilium cell;; cell part;; extracellular region;; extracellular region part;; organelle;; organelle part apical part of cell;; cell part;; cell projection;; cell surface;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle;; organelle part;; stereocilium 345.3940 272.2316 398.6548 304.9044 362.1187 617.2631 808.2145 838.3654 942.8741 972.1465 811.4856 926.7547 304.3540 372.3449 360.4899 291.5900 302.8741 305.0928 1343970 1419927_s_at 1 chr1:136403861-136404136 1 E4 chr1:136391236-136404462 1 E4 RSQ Mm.198119 NM_145510 1 1 98710 Rabif RAB interacting factor (Rabif), mRNA. guanyl-nucleotide exchange factor activity;; metal ion binding;; protein transport;; small GTPase mediated signal transduction;; transport;; zinc ion binding binding;; enzyme regulator activity ion binding;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; establishment of localization;; localization;; regulation of biological process cell communication;; establishment of localization;; establishment of protein localization;; macromolecule localization;; regulation of biological process;; regulation of cellular process;; transport 1199.3861 1208.9572 1482.5526 1073.5011 1194.4297 1204.6135 4511.7630 4525.4852 5887.2630 5463.7630 4397.0854 5389.6519 2455.4083 3278.0408 2486.8419 2459.8665 2691.0019 2450.2706 1330965 1420088_at 12 C1-C3 chr12:56590464-56590506 12 C1 UGA Mm.170515 18035 Nfkbia Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 63.3187 70.6266 87.9301 48.0558 60.5127 73.4391 539.4166 549.3691 1009.0486 991.8128 582.4123 992.4099 391.7701 515.2200 529.7199 335.2197 437.2457 377.5505 1331105 1420342_at 12 A3 chr12:33511200-33511722 12 A3 UGA Mm.440246 14546 Gdap10 Ganglioside-induced differentiation associated protein 10 response to retinoic acid response to stimulus response to chemical stimulus;; response to external stimulus 100.3442 103.8383 112.0288 80.1553 89.1643 69.5161 63.1466 64.9401 101.3313 98.0665 63.4953 83.0079 33.4403 50.0835 46.8609 40.9461 39.7924 40.9233 1331196 1420454_at 11 B2 chr11:60005022-60005479 11 B2 UGA Mm.296366 19377 RP23-456O18.3 Rai1 Retinoic acid induced 1 (Rai1), transcript variant 1, mRNA cytoplasm;; metal ion binding;; negative regulation of multicellular organism growth;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; skeletal system development;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; negative regulation of biological process;; negative regulation of growth;; negative regulation of multicellular organismal process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process 101.6655 116.5201 97.7893 132.9006 136.4929 123.3746 751.6519 678.1258 1445.0073 1199.5999 612.2388 1302.2075 152.7259 126.4229 104.8535 158.8062 92.2823 91.5046 1331270 1420558_at 1 86.6 cM chr1:166079630-166080083 1 H2.2 chr1:166053831-166079876 1 H2.2 RSQ Mm.3337 NM_011347 1 1 20344 Selp selectin, platelet (Selp), mRNA. Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 53.8167 55.3617 46.6089 48.0767 60.9839 57.8751 86.4955 85.0225 119.1528 110.5827 89.6762 109.1453 34.8972 52.1566 44.7254 40.2297 45.4187 43.7427 1331346 1420667_at 11 chr11:75582506-75583066 11 B5 chr11:75582591-75609559 11 B5 RSQ Mm.5137 NM_007873 1 1 13447 RP23-78H4.2 Doc2b double C2, beta (Doc2b), mRNA. calcium ion binding;; calcium-dependent phospholipid binding;; membrane;; synaptic vesicle;; transport;; transporter activity cell;; cell part;; organelle;; synapse;; synapse part cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle;; synapse part;; synaptic vesicle;; vesicle binding;; transporter activity ion binding;; lipid binding establishment of localization;; localization establishment of localization;; transport 74.4927 69.1700 71.4835 76.9254 63.7483 74.1579 680.0829 731.2124 853.7629 867.3510 749.3587 745.1623 247.5408 417.4852 316.7284 250.1682 500.0177 442.1294 1344208 1420940_x_at 1 86.5 cM chr1:171620595-171622674 1 H3 chr1:171585631-171623657 1 H3 RSQ Mm.20954 NM_009063 1 1 19737 Rgs5 regulator of G-protein signaling 5 (Rgs5), mRNA. G-protein coupled receptor protein signaling pathway;; GTPase activator activity;; negative regulation of signal transduction;; signal transducer activity enzyme regulator activity;; molecular transducer activity enzyme activator activity;; nucleoside-triphosphatase regulator activity;; signal transducer activity biological regulation;; cellular process;; negative regulation of biological process;; regulation of biological process cell communication;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 283.5739 336.8788 410.4656 174.4394 234.9659 224.1130 627.8319 662.0330 572.7123 572.5171 624.6979 659.2118 269.8551 299.0731 312.9852 287.4601 376.4363 400.7402 1331586 1420985_at 3 chr3:88786292-88786833 3 F1 chr3:88769733-88883297 3 F1 RSQ Mm.130752 NM_138679 1 1 192195 Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) (Ash1l), mRNA. Lysine degradation;; Tight junction CLASS Metabolism; Amino Acid Metabolism; Lysine degradation [PATH:mmu00310] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] cell junction;; chromatin modification;; DNA binding;; histone-lysine N-methyltransferase activity;; metal ion binding;; methyltransferase activity;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; tight junction;; transcription;; transferase activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; protein binding;; transferase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 42.5751 29.2195 43.7361 44.0788 58.1670 36.5856 1973.5586 1927.1863 760.4818 719.8664 1967.2630 695.0346 200.7800 141.9667 190.8598 284.3779 173.0591 137.4432 1331591 1420991_at 19 chr19:36187159-36191361 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 31.9519 41.9799 27.5361 44.6846 32.7657 32.2877 1537.9415 1602.5127 543.4858 572.1462 1537.0619 552.3462 150.5234 110.2621 120.1813 182.5408 134.9352 92.3970 1331592 1420992_at 19 chr19:36186663-36186994 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 130.3147 142.2726 199.3636 113.3083 106.4186 150.3131 727.8373 741.9241 833.9297 840.3169 745.0505 859.4762 216.4525 272.6037 271.8186 259.5930 295.1997 251.7090 1344415 1421679_a_at 17 15.23 cM chr17:29235417-29235782 17 A3.3 chr17:29230716-29237667 17 A3.3 RSQ Mm.477981 NM_007669 2 1 12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA. ATM Signaling Pathway;; Cell Cycle: G1/S Check Point;; Cell Cycle: G2/M Checkpoint;; Cyclins and Cell Cycle Regulation;; Effects of calcineurin in Keratinocyte Differentiation;; Erythropoietin mediated neuroprotection through NF-kB;; Influence of Ras and Rho proteins on G1 to S Transition;; p53 Signaling Pathway Bladder cancer;; Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases;;; ErbB signaling pathway;; Glioma;; Melanoma;; p53 signaling pathway;; Pathways in cancer;; Prostate cancer cell cycle;; cell cycle arrest;; cyclin binding;; cyclin-dependent protein kinase holoenzyme complex;; cyclin-dependent protein kinase inhibitor activity;; cytoplasm;; cytosol;; kinase activity;; metal ion binding;; negative regulation of apoptosis;; negative regulation of cell proliferation;; negative regulation of cyclin-dependent protein kinase activity;; nucleus;; positive regulation of B cell proliferation;; positive regulation of programmed cell death;; protein binding;; protein kinase inhibitor activity;; regulation of cell cycle;; response to DNA damage stimulus;; response to UV;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; kinase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell cycle;; cell cycle process;; cell death;; cell proliferation;; cellular metabolic process;; leukocyte activation;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 86.7993 87.0452 63.6171 74.8562 90.2992 74.9252 230.5079 234.4752 357.3814 439.0449 257.8092 478.9576 148.2599 136.7346 177.0608 133.7550 121.7414 124.2018 1332209 1421854_at 5 A3|5 7.0 cM chr5:20882365-20882816 5 A3 UGA Mm.292100 14190 Fgl2 Fibrinogen-like protein 2, mRNA (cDNA clone MGC:19044 IMAGE:4189071) cytolysis;; extracellular region;; receptor binding;; signal transduction extracellular region binding protein binding biological regulation;; cellular process;; death;; regulation of biological process cell communication;; cell death;; regulation of biological process;; regulation of cellular process 16.2991 14.9732 19.2545 19.3883 20.3214 17.6655 195.6063 186.5215 288.2630 340.3263 191.3883 413.0760 145.0481 117.3004 145.6007 105.5925 102.8611 51.1564 1332210 1421855_at 5 A3|5 7.0 cM chr5:20883636-20884037 5 A3 UGA Mm.292100 14190 Fgl2 Fibrinogen-like protein 2, mRNA (cDNA clone MGC:19044 IMAGE:4189071) cytolysis;; extracellular region;; receptor binding;; signal transduction extracellular region binding protein binding biological regulation;; cellular process;; death;; regulation of biological process cell communication;; cell death;; regulation of biological process;; regulation of cellular process 455.0102 297.6519 421.8700 405.3796 427.7516 731.8723 677.5097 682.5045 595.4179 634.7235 642.6164 637.9224 238.1206 366.8761 277.6180 226.6614 325.1630 325.2075 1344488 1421957_a_at 16 22.85 cM chr16:32471767-32471880 16 B3 chr16:32451788-32472101 16 B3 RSQ Mm.390903 NM_009981 1 1 13026 Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform (Pcyt1a), mRNA. Aminophosphonate metabolism;; Glycerophospholipid metabolism;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] Metabolism; Metabolism of Other Amino Acids; Aminophosphonate metabolism [PATH:mmu00440] biosynthetic process;; catalytic activity;; choline-phosphate cytidylyltransferase activity;; cytoplasm;; endoplasmic reticulum membrane;; glycogen granule;; membrane;; nucleotidyltransferase activity;; phosphatidylcholine biosynthetic process;; phosphatidylcholine biosynthetic process;; phospholipid biosynthetic process;; response to abiotic stimulus;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process;; response to stimulus alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; organophosphate metabolic process;; primary metabolic process;; response to abiotic stimulus 15061.6870 17007.9021 19241.4850 13646.8476 11566.6066 15092.5656 17311.5408 17626.1305 13242.8584 13524.8116 17479.4058 13585.2875 1232.6138 1610.5271 2823.0137 1763.3971 2121.9924 1128.1347 1344655 1422557_s_at 8 45.0 cM chr8:96703191-96704176 8 C5 chr8:96702988-96704227 8 C5 RSQ Mm.192991 NM_013602 1 1 17748 Mt1 metallothionein 1 (Mt1), mRNA. cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 306.3425 329.0498 426.6099 363.3741 392.7075 447.3186 565.6472 531.9279 553.1219 564.5976 577.7242 508.7587 257.6285 309.6789 236.8772 217.0964 252.9191 294.0813 1332998 1422904_at 1 chr1:164806985-164807074 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 51.1544 57.1644 49.3399 83.8410 38.6608 62.9341 324.3741 402.0277 306.2734 322.8741 419.1408 263.7075 94.9129 120.4577 98.4432 105.3137 111.7462 152.5590 1344723 1422905_s_at 1 chr1:164806589-164806972 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 120.0192 190.8862 144.7630 124.0976 150.2331 132.1156 121.8131 115.7054 173.5499 137.0852 120.6014 139.7368 71.1502 74.0252 69.9336 55.9884 60.5981 68.6808 1333034 1422953_at 17 A3.2 chr17:18030321-18030898 17 A3.2 UG5 Mm.477887 14289 Fpr2 Formyl peptide receptor 2 (Fpr2), mRNA Neuroactive ligand-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 54.4747 50.8881 149.3741 48.6285 173.4260 59.5784 332.4896 313.9419 387.9877 388.7630 356.3186 440.7630 164.4722 205.9289 227.5240 235.6415 171.2371 150.2630 1333114 1423062_at 11 1.35 cM chr11:7106270-7106593 11 A1 chr11:7106088-7113926 11 A1 RSQ Mm.29254 NM_008343 1 1 16009 RP23-20C9.1 Igfbp3 insulin-like growth factor binding protein 3 (Igfbp3), mRNA. p53 signaling pathway CLASS Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] extracellular region;; extracellular space;; growth factor binding;; insulin-like growth factor binding;; negative regulation of cell proliferation;; negative regulation of protein amino acid phosphorylation;; nucleus;; osteoblast differentiation;; protein amino acid phosphorylation;; regulation of cell growth cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; cell growth;; cell proliferation;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; ossification;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process 110.1895 122.7943 153.5161 53.9985 58.3791 65.2511 3851.2575 3763.3230 4100.3396 4175.4638 3917.4368 4155.0795 844.5731 784.3094 934.8195 833.1458 935.9843 662.7492 1333245 1423233_at 16 A2|16 9.0 cM chr16:15888053-15888517 16 A2 UGA Mm.347407 12609 Cebpd CCAAT/enhancer binding protein (C/EBP), delta (Cebpd), mRNA DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; promoter binding;; protein binding;; protein dimerization activity;; protein heterodimerization activity;; protein homodimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; specific RNA polymerase II transcription factor activity;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 165.2561 232.3278 255.7444 354.3494 322.3257 312.8786 663.8505 626.6570 545.2669 533.3518 666.2352 631.0804 241.0987 325.1287 240.1790 297.4785 355.5674 398.6467 1333522 1423559_at 7 23.5 cM chr7:53682916-53683489 7 B4 chr7:53651866-53694074 7 B4 RSQ Mm.249386 NM_001112739 2 1 16502 Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 (Kcnc1), transcript variant A, mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 2528.2593 1285.0605 2901.7901 989.1094 1210.6190 983.6390 615.3186 638.4938 636.1375 576.0434 622.9057 589.0964 181.8186 230.5933 230.4479 206.7074 307.3741 320.0681 1333550 1423597_at 5 chr5:68013016-68013563 5 C3.1 chr5:68009378-68238670 5 C3.1 RSQ Mm.153230 NM_009727 2 1 11980 Atp8a1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (Atp8a1), transcript variant 2, mRNA. ATP binding;; ATP biosynthetic process;; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;; catalytic activity;; cytoplasmic vesicle;; hydrolase activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; integral to membrane;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; nucleotide binding;; phospholipid transport;; phospholipid-translocating ATPase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; vesicle binding;; catalytic activity;; transporter activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; nitrogen compound metabolic process;; primary metabolic process;; transport 81.2035 119.7275 113.4132 96.7983 78.6596 84.5784 150.3205 141.4488 282.7674 237.6166 156.2597 230.8396 99.6768 69.5696 93.7160 117.7849 85.7773 83.0225 1333897 1424067_at 9 7.0 cM chr9:20832733-20833172 9 A3 chr9:20820403-20833241 9 A3 RSQ Mm.435508 NM_010493 1 1 15894 Icam1 intercellular adhesion molecule 1 (Icam1), mRNA. Adhesion Molecules on Lymphocyte;; B Lymphocyte Cell Surface Molecules;; CTL mediated immune response against target cells;; Monocyte and its Surface Molecules;; Neutrophil and Its Surface Molecules;; T Cytotoxic Cell Surface Molecules;; T Helper Cell Surface Molecules Cell adhesion molecules (CAMs);; Leukocyte transendothelial migration CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670];; Natural killer cell mediated cytotoxicity cell adhesion;; cell adhesion mediated by integrin;; cell-cell adhesion;; external side of plasma membrane;; immunological synapse;; integral to membrane;; leukocyte adhesion;; membrane;; protein binding;; regulation of cell adhesion;; T cell antigen processing and presentation cell;; cell part cell part;; cell surface;; membrane;; membrane part binding protein binding biological adhesion;; biological regulation;; cellular process;; immune system process;; regulation of biological process;; response to stimulus antigen processing and presentation;; cell adhesion;; immune effector process;; immune response;; regulation of biological process;; regulation of cellular process 909.7936 836.4392 983.1690 1061.2713 2533.6486 966.6334 13.1668 14.7834 32.7793 25.5397 15.6726 27.9580 12.1927 14.3410 10.8553 16.2901 17.4474 13.8233 1334062 1424279_at 3 44.8 cM chr3:82835603-82836150 3 E3 chr3:82830074-82837549 3 E3 RSQ Mm.88793 NM_010196 2 1 14161 Fga fibrinogen alpha chain (Fga), transcript variant 2, mRNA. Complement and coagulation cascades CLASS Cellular Processes; Immune System; Complement and coagulation cascades [PATH:mmu04610] blood coagulation;; cell cortex cell;; cell part cell part;; intracellular;; intracellular part biological regulation;; multicellular organismal process;; response to stimulus coagulation;; regulation of biological quality;; regulation of body fluid levels;; response to external stimulus;; response to stress 197.1894 215.9323 185.3704 247.6566 223.1626 187.5363 740.9057 722.6335 1643.5945 1548.8396 706.3995 1452.3215 623.4708 498.2980 630.0106 510.2520 464.9516 503.9633 1334205 1424457_at 18 B2 chr18:36830844-36834637 18 B2 UG5 Mm.89673 225372 Apbb3 Amyloid beta (A4) precursor protein-binding, family B, member 3 (Apbb3), mRNA negative regulation of apoptosis;; protein binding binding protein binding biological regulation;; cellular process;; death;; developmental process;; negative regulation of biological process;; regulation of biological process cell death;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 824.9852 712.0659 1610.9019 536.1640 742.2856 949.8464 548.5184 561.3741 570.5668 562.1031 523.8246 536.0719 156.7904 205.8261 283.3828 200.3573 294.5273 292.9585 1334316 1424598_at 9 26.0 cM chr9:44444736-44445137 9 A5.2 chr9:44412974-44448814 9 A5.2 RSQ Mm.267061 NM_007841 3 1 13209 Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), transcript variant 3, mRNA. ATP binding;; ATP-dependent helicase activity;; cytoplasm;; helicase activity;; hydrolase activity;; nucleic acid binding;; nucleotide binding;; RNA binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity hydrolase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding 2835.7402 6489.5939 3320.4540 2143.3581 2838.8236 2835.0990 2310.2908 2363.1779 2001.0926 2172.4964 2260.7630 2221.5488 876.9485 916.9275 846.7059 864.6558 971.7345 767.6399 1345101 1424607_a_at 3 chr3:42306621-42308720 3 B RSQ XR_030788 15 15 100039204 LOC100039204 PREDICTED: hypothetical protein LOC100039204 (LOC100039204), misc RNA. 2752.8927 6134.5039 2988.1002 1979.8232 2616.0323 2752.8459 2286.4086 2333.3775 2172.9304 2207.8772 2335.1831 2330.6435 916.8749 947.5559 941.3981 961.7436 901.1189 802.9615 1345103 1424609_a_at IPA Mus musculus, Similar to RIKEN cDNA 1700066C05 gene, clone MGC:28125 IMAGE:3980327, mRNA, complete cds 305.6736 196.0819 332.6246 209.1864 225.2713 331.0535 1882.1954 1981.8484 1929.2824 1862.2814 1861.9929 1737.2725 471.4183 471.1816 642.1553 553.2019 655.3545 381.7645 1334343 1424638_at 17 15.23 cM chr17:29237151-29237610 17 A3.3 chr17:29230716-29237667 17 A3.3 RSQ Mm.477981 NM_007669 2 1 12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA. ATM Signaling Pathway;; Cell Cycle: G1/S Check Point;; Cell Cycle: G2/M Checkpoint;; Cyclins and Cell Cycle Regulation;; Effects of calcineurin in Keratinocyte Differentiation;; Erythropoietin mediated neuroprotection through NF-kB;; Influence of Ras and Rho proteins on G1 to S Transition;; p53 Signaling Pathway Bladder cancer;; Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases;;; ErbB signaling pathway;; Glioma;; Melanoma;; p53 signaling pathway;; Pathways in cancer;; Prostate cancer cell cycle;; cell cycle arrest;; cyclin binding;; cyclin-dependent protein kinase holoenzyme complex;; cyclin-dependent protein kinase inhibitor activity;; cytoplasm;; cytosol;; kinase activity;; metal ion binding;; negative regulation of apoptosis;; negative regulation of cell proliferation;; negative regulation of cyclin-dependent protein kinase activity;; nucleus;; positive regulation of B cell proliferation;; positive regulation of programmed cell death;; protein binding;; protein kinase inhibitor activity;; regulation of cell cycle;; response to DNA damage stimulus;; response to UV;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; kinase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell cycle;; cell cycle process;; cell death;; cell proliferation;; cellular metabolic process;; leukocyte activation;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 404.1059 516.7383 449.4993 621.6116 596.6417 511.4949 953.5615 1016.9887 2841.0170 2711.1166 1015.2672 2667.8203 897.4399 939.4244 931.2811 1954.4339 1721.6484 1168.7522 1334422 1424735_at 2 chr2:32270714-32271132 2 B chr2:32270006-32306939 2 B RSQ Mm.37395 NM_146118 1 1 227731 RP23-255P20.1 Slc25a25 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 (Slc25a25), nuclear gene encoding mitochondrial protein, mRNA. binding;; calcium ion binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding ion binding establishment of localization;; localization establishment of localization;; transport 99.8547 61.6280 96.6060 61.1691 59.4574 84.2550 127.0060 105.6040 147.7085 110.9898 115.2089 147.2075 61.1878 68.9934 70.9562 55.8995 68.5003 79.2172 1334625 1425014_at 6 chr6:92117449-92117773 6 D1 chr6:92089771-92117953 6 D1 RSQ Mm.87062 NM_011630 1 1 22026 Nr2c2 nuclear receptor subfamily 2, group C, member 2 (Nr2c2), mRNA. DNA binding;; ligand-dependent nuclear receptor activity;; metal ion binding;; nucleus;; receptor activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; spermatocyte division;; spermatogenesis;; spermatogenesis;; steroid hormone receptor activity;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; reproduction;; reproductive process biosynthetic process;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 34.9231 32.1933 39.0085 34.1061 38.6470 36.7849 47.3997 39.6747 120.2125 113.8210 37.3176 120.0190 32.7201 35.2193 47.9810 39.4218 35.8014 30.6653 1334673 1425079_at 8 chr8:72602280-72603860 8 B3.3 chr8:72596830-72603951 8 B3.3 RSQ Mm.37974 NM_181540 1 1 107770 Tm6sf2 transmembrane 6 superfamily member 2 (Tm6sf2), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 38.9533 39.4908 38.3878 58.2987 50.3396 45.9627 73.8826 70.8215 132.3589 129.2080 71.3789 113.0168 56.4301 53.5581 50.3091 40.4675 54.6455 48.4058 1334790 1425282_at 13 A5 chr13:47341178-47341731 13 A5 UG5 Mm.287609 218215 Rnf144b Ring finger protein 144B (Rnf144b), mRNA apoptosis;; integral to membrane;; ligase activity;; membrane;; metal ion binding;; modification-dependent protein catabolic process;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; death;; metabolic process catabolic process;; cell death;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 79.9056 83.9020 81.6779 100.8700 126.0337 79.6656 175.8340 236.5370 335.6677 292.6611 227.7266 312.0848 143.3983 104.0944 151.3371 115.8101 116.8306 131.1521 1334803 1425303_at 11 1.0 cM chr11:5801000-5801377 11 A1 chr11:5800825-5849602 11 A1 RSQ Mm.220358 NM_010292 1 1 103988 RP23-340E18.1 Gck glucokinase (Gck), mRNA. Amino sugar and nucleotide sugar metabolism;; Glycolysis / Gluconeogenesis;; Insulin signaling pathway;; Maturity onset diabetes of the young CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Galactose metabolism [PATH:mmu00052] Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism [PATH:mmu00500] Metabolism; Carbohydrate Metabolism; Amino sugar and nucleotide sugar met;; Metabolic pathways;; Starch and sucrose metabolism;; Type II diabetes mellitus ATP binding;; carbohydrate metabolic process;; carbohydrate phosphorylation;; carbohydrate phosphorylation;; cellular glucose homeostasis;; glucokinase activity;; glucokinase activity;; glucose homeostasis;; glucose metabolic process;; glucose metabolic process;; glycolysis;; hexokinase activity;; kinase activity;; mitochondrion;; NADP metabolic process;; nucleotide binding;; phosphotransferase activity, alcohol group as acceptor;; positive regulation of insulin secretion;; protein binding;; regulation of insulin secretion;; regulation of potassium ion transport;; soluble fraction;; transferase activity cell;; cell part;; organelle cell fraction;; cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; catabolic process;; cell communication;; cellular homeostasis;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; generation of a signal involved in cell-cell signaling;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of localization;; secondary metabolic process;; secretion by cell;; transport 444.9556 578.4796 481.6119 320.9537 309.1652 524.2029 137.4483 161.0408 137.4896 157.6688 147.2714 152.1246 50.6398 46.0774 42.7239 38.7712 32.2961 48.6472 1334842 1425362_at 5 chr5:138104059-138104479 5 G2 chr5:138104037-138125921 5 G2 RSQ Mm.260869 NM_145566 1 1 231801 Agfg2 ArfGAP with FG repeats 2 (Agfg2), transcript variant 1, mRNA. ARF GTPase activator activity;; metal ion binding;; regulation of ARF GTPase activity;; zinc ion binding binding;; enzyme regulator activity enzyme activator activity;; ion binding;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 436.9772 565.4297 548.2372 328.7606 300.2630 533.0057 238.4329 294.7137 228.0360 239.1902 241.7933 263.2127 70.7046 96.5410 117.7430 87.8747 121.8584 79.4824 1334929 1425514_at 13 50.0 cM chr13:102453666-102454171 13 D1 chr13:102450715-102462602 13 D1 RSQ Mm.259333 NM_001024955 2 1 18708 Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 1, mRNA. AKT Signaling Pathway;; B Cell Survival Pathway;; Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK);; Corticosteroids and cardioprotection;; CTCF: First Multivalent Nuclear Factor;; CXCR4 Signaling Pathway;; EGF Signaling Pathway;; Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia;; Fc Epsilon Receptor I Signaling in Mast Cells;; Growth Hormone Signaling Pathway;; Human Cytomegalovirus and Map Kinase Pathways;; IGF-1 Signaling Pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages;; Influence of Ras and Rho proteins on G1 to S Transition;; Inhibition of Cellular Proliferation by Gleevec;; Insulin Signaling Pathway;; mTOR Signaling Pathway;; Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation;; Nerve growth factor pathway (NGF);; NFAT and Hypertrophy of the heart (Transcription in the broken heart);; PDGF Signaling Pathway;; Phospholipase C Signaling Pathway;; Phospholipids as signalling intermediaries;; PTEN dependent cell cycle arrest and apoptosis;; Rac 1 cell motility signaling pathway;; Ras Signaling Pathway;; Ras-Independent pathway in NK cell-mediated cytotoxicity;; Regulation of BAD phosphorylation;; Regulation of eIF4e and p70 S6 Kinase;; Role of ERBB2 in Signal Transduction and Oncology;; Role of Erk5 in Neuronal Survival;; Role of nicotinic acetylcholine receptors in the regulation of apoptosis;; Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration;; Signaling of Hepatocyte Growth Factor Receptor;; Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway;; T Cell Receptor Signaling Pathway;; The Co-Stimulatory Signal During T-cell Activation;; The IGF-1 Receptor and Longevity;; Thrombin signaling and protease-activated receptors;; TPO Signaling Pathway;; Transcription factor CREB and its extracellular signals;; Trefoil Factors Initiate Mucosal Healing;; Trka Receptor Signaling Pathway;; Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Acute myeloid leukemia;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Colorectal cancer;; Endometrial cancer;; ErbB signaling pathway;; Fc epsilon RI signaling pathway;; Focal adhesion;; Glioma;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Leukocyte transendothelial migration;; Melanoma;; mTOR signaling pathway;; Natural killer cell mediated cytotoxicity;; Neurotrophin signaling pathway;; Non-small cell lung cancer CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; VEGF signaling pathway [PATH:mmu04370] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Informatio;; Pancreatic cancer;; Pathways in cancer;; Phosphatidylinositol signaling system;; Prostate cancer;; Regulation of actin cytoskeleton;; Renal cell carcinoma;; Small cell lung cancer;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway;; Type II diabetes mellitus;; VEGF signaling pathway 1-phosphatidylinositol-3-kinase activity;; B cell differentiation;; cytoplasm;; cytosol;; insulin receptor substrate binding;; intracellular;; kinase activity;; membrane;; negative regulation of apoptosis;; negative regulation of apoptosis;; negative regulation of cell-matrix adhesion;; negative regulation of osteoclast differentiation;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; positive regulation of cell migration;; protein amino acid phosphorylation;; protein binding;; signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; catalytic activity;; enzyme regulator activity kinase regulator activity;; protein binding;; transferase activity biological adhesion;; biological regulation;; cellular process;; death;; developmental process;; immune system process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; cell activation;; cell adhesion;; cell communication;; cell death;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; immune system development;; leukocyte activation;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of localization;; regulation of locomotion;; regulation of multicellular organismal process 108.7467 120.2968 55.2427 83.3823 99.7964 120.1168 7601.7352 7438.6597 9111.7046 8489.4064 7528.0867 8342.2805 3179.7718 1399.4852 2538.9511 1933.6239 2923.1461 2082.8401 1334990 1425631_at 19 chr19:36807805-36808192 19 C2 chr19:36806220-36811094 19 C2 RSQ Mm.24724 NM_016854 1 1 53412 Ppp1r3c protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen biosynthetic process;; glycogen metabolic process;; protein binding;; protein targeting binding protein binding cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport 494.4093 474.9598 614.5408 1407.8149 1181.4982 2400.8203 2294.9077 2190.1389 2245.2478 2252.6339 2259.5349 2327.4852 925.7221 950.2809 1215.3054 649.2134 764.0944 680.9244 1345554 1425837_a_at 3 chr3:51055003-51055460 3 C chr3:51028368-51055576 3 C RSQ Mm.86541 NM_009834 2 2 12457 Ccrn4l CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA. Selective expression of chemokine receptors during T-cell polarization rhythmic process rhythmic process 141.7900 125.3745 122.2632 160.5860 160.9295 128.7504 73.1578 76.2143 269.5804 235.2393 75.9593 240.4633 109.2820 74.7242 79.8504 63.7484 67.8046 86.2546 1335161 1425965_at 5 chr5:125866334-125870928 5 G1.1 RSQ XM_001479835 1 1 100048105 LOC100048105 PREDICTED: similar to Ubc protein, transcript variant 2 (LOC100048105), mRNA. PPAR signaling pathway CLASS Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] 2958.7684 3393.0912 4198.4763 3231.1797 5880.3783 5638.9297 6624.1444 7002.5091 8502.2497 8656.9348 7080.8425 8364.4378 2673.4290 4010.6292 3445.5307 2750.3834 5525.7050 6068.9050 1335210 1426114_at IPA Unknown 1963.0661 2026.9501 2078.3730 2200.4229 1811.3703 2258.6339 4148.3515 4008.6530 3778.1128 3530.1850 4122.3605 3551.2695 1585.2491 1496.6111 1758.1376 1741.8214 1744.9808 1552.3649 1345786 1426235_a_at 1 chr1:155754454-155755308 1 G3 chr1:155747074-155756844 1 G3 RSQ Mm.210745 NM_008131 1 1 14645 Glul glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA. Alanine, aspartate and glutamate metabolism;; Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan biosynthesis [PATH:mmu0;; Nitrogen metabolism;; Peptidoglycan biosynthesis ATP binding;; catalytic activity;; cytoplasm;; glutamate-ammonia ligase activity;; glutamine biosynthetic process;; intracellular;; ligase activity;; mitochondrion;; nitrogen compound metabolic process;; nucleotide binding;; response to glucose stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to chemical stimulus 1326.3930 1191.8581 974.3528 1114.0166 1155.3994 1339.7366 6927.6529 6899.3741 5886.7039 6323.4297 6905.6186 6344.3464 2352.4060 2770.9492 3390.2249 2746.8536 2554.6209 2686.6089 1345787 1426236_a_at 1 chr1:155756223-155756784 1 G3 chr1:155747074-155756844 1 G3 RSQ Mm.210745 NM_008131 1 1 14645 Glul glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA. Alanine, aspartate and glutamate metabolism;; Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan biosynthesis [PATH:mmu0;; Nitrogen metabolism;; Peptidoglycan biosynthesis ATP binding;; catalytic activity;; cytoplasm;; glutamate-ammonia ligase activity;; glutamine biosynthetic process;; intracellular;; ligase activity;; mitochondrion;; nitrogen compound metabolic process;; nucleotide binding;; response to glucose stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to chemical stimulus 123.0420 133.3818 140.3550 182.0122 175.1103 145.3085 177.4953 205.9852 458.9332 339.1096 191.7385 339.9714 105.0679 87.1669 117.0526 74.0406 90.4069 97.7283 1335426 1426446_at 8 chr8:122686736-122687249 8 E1 chr8:122669128-122687318 8 E1 RSQ Mm.101958 NM_172286 1 1 234797 6430548M08Rik RIKEN cDNA 6430548M08 gene (6430548M08Rik), mRNA. 337.6804 338.0365 897.8044 233.7075 275.7340 303.1219 501.1893 505.0569 744.4696 678.4047 492.6994 659.0964 372.1456 241.7120 331.1464 259.2585 183.5748 210.0638 1335676 1426808_at 14 chr14:47993534-48005842 14 C1 RSQ Mm.248615 NM_010705 2 1 16854 Lgals3 lectin, galactose binding, soluble 3 (Lgals3), transcript variant 2, mRNA. cell differentiation;; cytoplasm;; cytoplasm;; extracellular matrix organization;; IgE binding;; nucleus;; nucleus;; protein binding;; proteinaceous extracellular matrix;; skeletal system development;; sugar binding cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding carbohydrate binding;; protein binding cellular component organization;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; cellular developmental process;; extracellular structure organization;; multicellular organismal development 32.7911 29.9082 30.6245 28.4432 44.9766 29.5648 78.5539 87.4236 212.5964 191.2307 84.9827 177.5100 76.3944 76.2112 67.1412 93.7556 80.0893 73.9014 1335714 1426858_at 1 E2.3|1 64.1 cM chr1:121312137-121312619 1 E2.3 UGA Mm.3092 16324 Inhbb Inhibin beta-B subunit Cytokine-cytokine receptor interaction;; TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] extracellular region;; growth;; growth factor activity;; hormone activity;; negative regulation of insulin secretion extracellular region binding protein binding biological regulation;; cellular process;; establishment of localization;; growth;; localization;; negative regulation of biological process;; regulation of biological process cell communication;; cellular localization;; establishment of localization;; establishment of localization in cell;; generation of a signal involved in cell-cell signaling;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of transport;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of localization;; secretion by cell;; transport 94.0496 85.3250 104.6086 99.0428 117.1210 101.5938 534.1822 551.9059 1115.1781 998.9656 548.0636 1049.8640 305.1468 213.5108 305.1533 221.0183 250.4959 167.3495 1335858 1427035_at 14 chr14:70703392-70703860 14 D2 chr14:70703273-70748240 14 D2 RSQ Mm.270647 NM_001135152 3 1 213053 Slc39a14 solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 2, mRNA. ferrous iron transmembrane transporter activity;; integral to membrane;; ion transport;; iron ion transport;; membrane;; metal ion transmembrane transporter activity;; metal ion transport;; plasma membrane;; transport;; zinc ion binding;; zinc ion transmembrane transporter activity;; zinc ion transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 67.2103 61.6777 66.1078 53.6141 70.7729 67.5500 132.7359 136.8830 336.8695 369.3644 114.0280 424.8182 161.1338 155.0082 260.9169 124.1905 116.6953 107.3741 1336133 1427384_at 2 H2 chr2:160772766-160773158 2 H2 UGA Mm.122738 71389 RP23-384K10.1 Chd6 Chromodomain helicase DNA binding protein 6, mRNA (cDNA clone IMAGE:3597702) helicase activity;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity 145.3274 169.4884 130.1581 157.1871 182.3032 136.8730 512.9620 520.0769 618.3342 576.8471 505.7236 549.0709 142.4790 174.6236 175.0508 115.6528 154.0563 153.8371 1336304 1427638_at 9 23.0 cM chr9:48462401-48644050 9 A5.3 RSQ Mm.457803 NM_001033324 1 1 235320 Zbtb16 zinc finger and BTB domain containing 16 (Zbtb16), mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer anterior/posterior pattern formation;; DNA binding;; embryonic hindlimb morphogenesis;; embryonic limb morphogenesis;; embryonic pattern specification;; forelimb morphogenesis;; leg morphogenesis;; male germ-line stem cell division;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of transcription, DNA-dependent;; nucleus;; nucleus;; positive regulation of apoptosis;; protein binding;; protein binding;; regulation of transcription;; skeletal system development;; specific transcriptional repressor activity;; transcriptional repressor complex;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription repressor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; sexual reproduction 63.7524 100.6022 78.4372 88.7572 122.5125 101.5911 619.3721 605.6988 512.3169 492.7017 652.3240 476.1421 37.9391 43.5123 47.1655 36.6971 50.5820 47.1409 1346214 1427747_a_at 2 27.0 cM chr2:32240946-32241323 2 B chr2:32240156-32243259 2 B RSQ Mm.9537 NM_008491 1 1 16819 RP23-161B9.11 Lcn2 lipocalin 2 (Lcn2), mRNA. binding;; extracellular region;; response to virus;; transport;; transporter activity extracellular region binding;; transporter activity establishment of localization;; localization;; multi-organism process;; response to stimulus establishment of localization;; response to biotic stimulus;; response to other organism;; transport 867.6712 825.0383 813.2477 461.9614 640.6519 559.4638 1755.1658 1651.9580 2660.7334 2529.7075 1716.3969 2582.3156 1127.0408 1179.7574 1101.9711 994.0461 860.9721 859.9573 1346275 1427932_s_at 1 chr1:9226200-9228974 1 A2 RSQ XM_001472850 1 1 100039464 LOC100039464 PREDICTED: similar to gag protein, transcript variant 1 (LOC100039464), mRNA. 113.2984 145.5687 178.7431 160.1258 122.0618 85.1566 2022.3901 2068.3186 6563.1989 6610.9871 2083.5964 6908.7095 434.1351 562.1519 536.9156 313.0404 399.7279 277.0665 1336689 1428306_at 10 chr10:59412481-59412957 10 B4 chr10:59412422-59414518 10 B4 RSQ Mm.21697 NM_029083 1 1 74747 Ddit4 DNA-damage-inducible transcript 4 (Ddit4), mRNA. mTOR signaling pathway CLASS Environmental Information Processing; Signal Transduction; mTOR signaling pathway [PATH:mmu04150] apoptosis;; cytoplasm;; negative regulation of signal transduction cell;; cell part cell part;; intracellular;; intracellular part biological regulation;; cellular process;; death;; negative regulation of biological process;; regulation of biological process cell communication;; cell death;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 210.7563 248.3029 175.1834 254.5968 230.0939 212.2854 568.2269 576.4340 910.6148 834.5841 533.3693 807.8008 173.3186 241.4723 201.9950 117.3760 140.0004 154.3352 1336820 1428776_at 5 E5 chr5:104034768-104035330 5 E5 UGA Mm.7446 75750 Slc10a6 Solute carrier family 10 (sodium/bile acid cotransporter family), member 6 (Slc10a6), mRNA bile acid:sodium symporter activity;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; symporter activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 17807.0044 20450.9695 24270.3324 17224.4342 13159.5589 19404.8027 23774.9245 24576.4852 17716.8011 17756.8861 24517.5964 17863.6954 1033.7424 1019.6752 2204.3208 1109.7352 1748.1001 864.5223 1336865 1428942_at 8 45.0 cM chr8:96696756-96697386 8 C5 chr8:96696517-96697467 8 C5 RSQ Mm.147226 NM_008630 1 1 17750 Mt2 metallothionein 2 (Mt2), mRNA. cellular zinc ion homeostasis;; detoxification of copper ion;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 159.8594 96.5305 92.6462 130.8693 136.7388 238.5904 284.7408 257.7510 1491.9889 1412.7241 262.5376 1337.1505 511.9971 506.2394 595.2630 558.1104 471.4421 346.7177 1346626 1431213_a_at 8 UGA Mm.463370 Transcribed locus, weakly similar to XP_001379802.1 PREDICTED: similar to pol protein [Monodelphis domestica] 4470.4221 4713.6380 4560.0863 3847.3599 3595.9979 4428.2302 670.9358 665.8286 807.6354 838.6466 661.9893 825.5298 306.3124 258.7374 350.0964 302.0964 283.7407 288.3186 1346830 1432273_a_at 1 94.0 cM chr1:175262194-175262805 1 H3 chr1:175262016-175263634 1 H3 RSQ Mm.6393 NM_010045 1 1 13349 Darc Duffy blood group, chemokine receptor (Darc), mRNA. G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; inflammatory response;; integral to membrane;; membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; regulation of biological process;; regulation of cellular process;; response to external stimulus;; response to stress 782.4997 644.0964 964.4481 465.0243 418.2164 629.2550 2847.0386 2696.2835 1981.9405 2251.3057 2722.9379 2196.3751 973.7976 1019.9236 1038.3640 1017.3076 1076.6768 1022.8797 1346897 1433428_x_at 2 H1|2 89.0 cM chr2:157942194-157942355 2 H1 UG5 Mm.330731 21817 RP23-396G1.2 Tgm2 Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943) Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 231.2674 217.4957 372.9437 186.4809 256.1379 312.0112 367.7429 390.6645 456.0433 436.7816 371.3186 433.1717 182.9297 193.1415 198.7386 162.0709 265.5873 273.2217 1337297 1433598_at 8 A1.1 chr8:8682359-8682883 8 A1.1 UGA Mm.251655 234023 Arglu1 RIKEN cDNA 9430010O03 gene, mRNA (cDNA clone IMAGE:4502890) 63.1105 82.8617 93.7025 98.4511 98.2313 90.1634 16712.9199 16491.4865 17254.9414 16859.1734 16951.9314 17458.6531 8536.0934 5068.4118 7885.3186 6703.5269 9168.6632 6819.5502 1337327 1433691_at 19 chr19:36806257-36806814 19 C2 chr19:36806220-36811094 19 C2 RSQ Mm.24724 NM_016854 1 1 53412 Ppp1r3c protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen biosynthetic process;; glycogen metabolic process;; protein binding;; protein targeting binding protein binding cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport 209.2787 354.8163 306.1897 150.0916 192.4188 104.7252 304.0789 318.9772 306.5215 338.4297 314.8499 312.7955 112.8214 179.4808 190.3074 133.9854 148.4707 121.2928 1346968 1433757_a_at 14 B chr14:31998914-31999067 14 B UG5 Mm.298728 64652 Nisch Imidazoline receptor I-1-like protein actin cytoskeleton organization;; apoptosis;; cell communication;; cytoplasm;; cytosol;; endosome;; integrin binding;; membrane;; negative regulation of cell migration;; phosphoinositide binding;; plasma membrane;; protein binding;; Rac protein signal transduction;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity lipid binding;; protein binding;; signal transducer activity biological regulation;; cellular component organization;; cellular process;; death;; localization;; locomotion;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cell death;; cell motility;; cell motion;; localization of cell;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion 114.7258 120.3749 119.6632 111.2775 136.9752 128.6485 205.7183 218.4149 250.7948 264.5927 214.0057 244.0934 107.1790 122.1617 130.0901 134.6540 128.5610 142.5416 1337352 1433804_at 4 C6|4 46.3 cM chr4:100852069-100856981 4 C6 UGA Mm.289657 16451 RP23-336G7.2 Jak1 Janus kinase 1, mRNA (cDNA clone IMAGE:5148553) EGF Signaling Pathway;; IFN alpha signaling pathway;; IFN gamma signaling pathway;; IL 2 signaling pathway;; IL 4 signaling pathway;; IL 6 signaling pathway;; IL-10 Anti-inflammatory Signaling Pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; IL22 Soluble Receptor Signaling Pathway;; PDGF Signaling Pathway;; Stat3 Signaling Pathway Jak-STAT signaling pathway;; Pancreatic cancer CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Pancreatic cancer [PATH:mmu05212];; Pathways in cancer ATP binding;; cytokine-mediated signaling pathway;; cytoskeleton;; enzyme linked receptor protein signaling pathway;; Janus kinase activity;; kinase activity;; membrane;; non-membrane spanning protein tyrosine kinase activity;; nucleotide binding;; peptidyl-tyrosine phosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase cascade;; protein tyrosine kinase activity;; response to antibiotic;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; non-membrane-bounded organelle binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; response to chemical stimulus 311.4899 273.5820 372.2549 123.3374 258.4329 170.3646 1073.9590 1008.7879 1280.3741 1373.6406 1047.2931 1355.1301 466.1592 529.5078 521.1020 454.3997 392.3883 313.9057 1347155 1435137_s_at IPA 1200015M12Rik RIKEN cDNA 1200015M12 gene 37.9186 35.0649 35.6337 33.7630 35.5782 38.2934 50.4564 71.2900 87.4274 71.4520 67.3881 66.7127 28.0067 27.2285 23.6225 29.6627 33.2077 29.4021 1337862 1435767_at 9 chr9:40098621-40099186 9 A5.1 chr9:40076800-40099203 9 A5.1 RSQ Mm.290083 NM_001083917 3 1 235281 Scn3b sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; sodium channel activity;; sodium ion binding;; sodium ion transport;; transport;; voltage-gated ion channel activity cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 23.7276 23.9090 28.7192 25.1336 22.0813 27.0483 121.7392 137.3238 197.9381 195.7433 139.8875 179.4431 70.7070 86.9708 97.9104 96.8476 88.3448 70.7902 1347265 1435944_s_at 2 73.9 cM chr2:131005398-131005598 2 F1 chr2:131003024-131005748 2 F1 RSQ Mm.440169 NM_007682 1 1 12616 RP23-32L15.4 Cenpb centromere protein B (Cenpb), mRNA. chromatin binding;; chromosome;; chromosome, centromeric region;; DNA binding;; nucleic acid binding;; nucleus;; regulation of transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 158.3358 176.2682 177.5797 312.4591 233.3014 167.8737 780.7569 772.7304 1545.3383 1422.7902 751.1486 1458.5964 853.8615 628.4143 732.7743 560.6396 455.5380 372.8601 1337902 1435950_at 14 chr14:70972823-70973293 14 D2 chr14:70953862-70973350 14 D2 RSQ Mm.7598 NM_021877 1 1 15460 Hr hairless (Hr), mRNA. DNA binding;; metal ion binding;; negative regulation of transcription;; nuclear body;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; zinc ion binding cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1443.0070 902.1295 1371.1218 1033.4406 904.3991 1158.2260 549.7658 560.6155 2143.1672 2100.7630 504.7480 2175.6269 509.3776 844.7421 1033.9999 646.8443 585.0293 306.0313 1347360 1436689_a_at 1 chr1:169298245-169298401 1 H2.3 chr1:169280121-169298661 1 H2.3 RSQ Mm.330055 NM_019993 1 1 56752 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA. 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation 4-trimethylammoniobutyraldehyde dehydrogenase activity;; aldehyde dehydrogenase (NAD) activity;; carnitine metabolic process;; cytoplasm;; cytosol;; metabolic process;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor cell;; cell part cell part;; intracellular;; intracellular part catalytic activity oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 2132.8218 2313.6094 2279.1773 1632.0322 1846.8538 1737.6194 1207.9591 1280.5193 1310.6035 1316.5267 1192.9103 1379.0798 488.0336 609.9845 605.4068 478.7630 776.2570 766.5414 1338026 1436746_at 6 chr6:119919542-119940264 6 F1 chr6:119874355-119987797 6 F1 RSQ Mm.333349 NM_198703 1 1 232341 Wnk1 WNK lysine deficient protein kinase 1 (Wnk1), mRNA. ATP binding;; cytoplasm;; ion transport;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase inhibitor activity;; protein serine/threonine kinase activity;; regulation of cellular process;; soluble fraction;; transferase activity;; vesicular fraction cell;; cell part cell fraction;; cell part;; intracellular;; intracellular part binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; kinase regulator activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; regulation of biological process cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; transport 524.0192 873.7075 791.1605 307.7646 352.2107 472.9594 1386.5010 1473.5635 1217.1969 1431.3901 1417.4223 1500.7992 504.1524 766.2506 725.0438 756.0278 1024.1371 707.5618 1338029 1436766_at 6 B1 chr6:38518985-38519541 6 B1 UGA Mm.276133 192196 Luc7l2 LUC7-like 2 (S. cerevisiae) (Luc7l2), mRNA metal ion binding;; protein binding;; zinc ion binding binding ion binding;; protein binding 408.0408 509.9297 826.0589 290.7906 467.9852 583.8921 831.9937 900.7241 803.9646 840.0469 877.6527 819.2061 293.6618 338.6343 350.7931 285.1834 531.5274 462.9297 1338059 1436898_at 4 D2.2|4 57.6 cM chr4:126704853-126705318 4 D2.2 UG5 Mm.257276 71514 RP23-153M14.2 Sfpq Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) (Sfpq), mRNA RNA polymerase III transcription DNA binding;; DNA repair;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; RNA binding;; RNA splicing;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to stress 61.8896 68.7454 77.5084 90.8446 61.8346 77.3563 340.2855 327.0920 342.9125 324.4821 363.5089 312.8969 136.1223 199.1023 151.5819 143.2012 182.3139 190.1718 1338064 1436910_at 1 chr1:159106227-159122987 1 H1 chr1:159065313-159342726 1 H1 RSQ Mm.235028 NM_177644 1 1 226525 Rasal2 RAS protein activator like 2 (Rasal2), mRNA. 1372.0675 1109.4073 1429.8862 903.2599 776.9254 1136.7661 4093.1354 3995.7787 2893.0563 3037.0839 3926.6895 3145.3310 1432.7946 1410.8004 1477.9568 1381.2200 1528.2908 1563.0686 1347528 1437277_x_at 2 H1|2 89.0 cM chr2:157942194-157942355 2 H1 UGA Mm.330731 21817 RP23-396G1.2 Tgm2 Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943) Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 677.6724 469.2906 609.6344 537.8606 471.5644 528.9066 237.6797 244.9858 1031.1579 993.4510 272.6434 956.7375 307.5396 393.4332 504.3200 313.3426 282.5293 251.0767 1347565 1437398_a_at 1 chr1:169297696-169298074 1 H2.3 chr1:169280121-169298661 1 H2.3 RSQ Mm.330055 NM_019993 1 1 56752 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA. 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation 4-trimethylammoniobutyraldehyde dehydrogenase activity;; aldehyde dehydrogenase (NAD) activity;; carnitine metabolic process;; cytoplasm;; cytosol;; metabolic process;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor cell;; cell part cell part;; intracellular;; intracellular part catalytic activity oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 153.0686 205.4243 206.5377 81.4987 114.5586 128.6850 118.0712 124.8766 183.2404 167.9852 143.3056 157.0864 64.8900 79.2127 92.4365 66.8549 101.8815 89.9327 1347732 1438069_a_at 9 F1 chr9:107662113-107662156 9 F1 UGA Mm.259197 83486 Rbm5 RNA binding motif protein 5 (Rbm5), mRNA apoptosis;; intracellular;; metal ion binding;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus;; RNA binding;; RNA splicing;; spliceosomal complex;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding ion binding;; nucleic acid binding;; nucleotide binding cellular process;; death;; metabolic process cell death;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 15.5970 17.6997 18.6507 21.5104 24.3010 16.5261 1706.4576 1657.5697 2031.9928 2318.7218 1696.3744 2400.7840 1078.7013 969.4890 1326.1633 911.0775 799.9846 639.6704 1347820 1438385_s_at 8 C3 chr8:88051301-88051346 8 C3 UGA Mm.200423 108682 Gpt2 Glutamic pyruvate transaminase (alanine aminotransferase) 2, mRNA (cDNA clone MGC:37704 IMAGE:5065322) Alanine, aspartate and glutamate metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] biosynthetic process;; catalytic activity;; L-alanine:2-oxoglutarate aminotransferase activity;; pyridoxal phosphate binding;; transaminase activity;; transferase activity;; transferase activity, transferring nitrogenous groups binding;; catalytic activity cofactor binding;; lipid binding;; transferase activity;; vitamin binding metabolic process biosynthetic process 177.5629 161.6939 182.0105 178.4852 196.6826 220.1300 550.1301 550.2149 592.2986 656.2075 536.8637 604.3084 230.0212 396.5964 263.6886 262.3791 270.9367 304.9683 1338326 1438677_at 2 chr2:59160639-59176922 2 C1.1 chr2:58998906-59193262 2 C1.1 RSQ Mm.260938 NM_026361 2 1 227937 RP23-311G5.1 Pkp4 plakophilin 4 (Pkp4), transcript variant 1, mRNA. binding;; cell adhesion;; cell junction;; protein binding cell;; cell part cell part;; membrane;; membrane part binding protein binding biological adhesion;; cellular process cell adhesion 348.1187 407.5799 355.6297 351.6282 329.9930 269.0695 337.9409 350.7296 376.0464 358.0357 354.1087 365.3756 132.6213 118.5343 121.8748 109.2104 109.3411 104.9861 1338349 1438758_at 12 A1.3 IPA AL024210 expressed sequence AL024210 382.0130 630.7304 583.9739 377.1740 335.9928 510.9587 56.3407 58.6434 69.9458 56.3407 64.7579 64.5691 25.7117 31.1987 30.7198 34.1812 30.8778 30.9708 1338358 1438824_at 2 chr2:129026331-129026905 2 F1 UG5 Mm.406240 Transcribed locus 18.7765 20.6304 16.0828 21.1705 24.6489 16.5390 31.1854 26.2487 36.4440 45.2134 31.1939 49.9336 18.2036 22.5640 23.2114 16.0424 28.0583 15.2595 1338466 1441115_at 18 9.0 cM chr18:21125726-21126191 18 A2 IPA D18Ertd232e DNA segment, Chr 18, ERATO Doi 232, expressed 62.3019 39.4480 50.3521 48.2932 47.7694 54.0892 2467.8406 2460.9639 2246.7210 2309.7543 2444.3414 2459.0726 664.2395 916.7352 1259.6637 682.8227 923.0777 646.1873 1348119 1442025_a_at 9 chr9:48459944-48460104 9 A5.3 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 29.9435 53.1491 26.1531 41.4172 45.8551 38.0372 538.5243 592.7676 490.9788 532.1944 552.8870 522.0408 129.7918 232.6942 258.2096 185.5547 199.8664 167.1166 1338484 1442026_at 9 chr9:48460144-48460494 9 A5.3 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 102.0364 132.6590 100.2596 82.0411 77.8790 90.1637 106.6659 93.3822 90.6927 94.4416 96.9545 85.5279 55.9900 40.0732 37.1881 55.4861 81.8578 56.5740 1338495 1442494_at 17 C chr17:47145036-47145543 17 C UGA Mm.28234 224826 Ubr2 Ubiquitin protein ligase E3 component n-recognin 2 (Ubr2), mRNA ligase activity;; male meiosis I;; metal ion binding;; modification-dependent protein catabolic process;; nucleus;; protein binding;; protein binding;; protein catabolic process;; spermatogenesis;; ubiquitin ligase complex;; ubiquitin-dependent protein catabolic process;; ubiquitin-protein ligase activity;; ubiquitin-protein ligase activity;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; metabolic process;; reproduction;; reproductive process catabolic process;; cell cycle;; cell cycle process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; primary metabolic process;; reproductive process;; sexual reproduction 74.4192 48.7619 107.4835 107.5749 98.1812 95.1100 1050.2375 1121.8854 2694.9050 2752.8130 1151.9891 2685.5082 816.3741 930.9440 1011.2987 956.1259 893.9462 751.9297 1338746 1448181_at 6 chr6:90424643-90425023 6 D1 chr6:90412619-90425203 6 D1 RSQ Mm.41389 NM_023184 1 1 66277 Klf15 Kruppel-like factor 15 (Klf15), mRNA. DNA binding;; DNA binding;; glucose transport;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; positive regulation of transcription, DNA-dependent;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 294.7850 315.5833 221.8506 304.0301 356.1328 277.2894 937.9363 907.0593 1299.7133 1151.9785 917.7051 1182.8317 433.5647 256.8741 460.7716 291.7402 259.9207 266.0375 1338782 1448231_at 17 13.0 cM chr17:28537316-28537865 17 A3.3 chr17:28536039-28623057 17 A3.3 RSQ Mm.276405 NM_010220 1 1 14229 Fkbp5 FK506 binding protein 5 (Fkbp5), mRNA. binding;; cytoplasm;; isomerase activity;; nucleus;; peptidyl-prolyl cis-trans isomerase activity;; protein binding;; protein folding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 165.7075 182.2713 250.0637 114.2925 121.9046 116.1533 1804.1610 1815.2107 2244.7663 2353.4620 1750.2196 2388.8081 846.8803 1124.3838 870.4777 894.5282 917.7790 877.0172 1338839 1448306_at 12 chr12:56590943-56592243 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 605.4722 797.3774 241.9977 1044.7616 2713.7768 856.5815 60.0072 57.7634 126.2640 107.7231 56.7346 117.4833 35.0984 23.1433 29.4871 67.2878 68.1489 56.9569 1339138 1448680_at 12 51.0 cM chr12:105133323-105135281 12 E chr12:105133135-105143160 12 E RSQ Mm.439694 NM_009245 2 2 20702 Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C (Serpina1c), mRNA. endopeptidase inhibitor activity;; extracellular region;; protein amino acid N-linked glycosylation;; protein binding;; response to cytokine stimulus;; response to peptide hormone stimulus;; serine-type endopeptidase inhibitor activity extracellular region binding;; enzyme regulator activity enzyme inhibitor activity;; protein binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; response to chemical stimulus;; response to endogenous stimulus 71.1006 68.7507 84.5056 103.4840 95.9892 68.7852 120.0587 98.4362 239.4045 208.0408 110.1700 203.0835 111.1766 87.2698 88.9997 58.7128 80.2024 73.2533 1339148 1448690_at 8 chr8:128554040-128554462 8 E2 chr8:128519001-128554585 8 E2 RSQ Mm.10800 NM_008430 1 1 16525 Kcnk1 potassium channel, subfamily K, member 1 (Kcnk1), mRNA. endosome;; integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 82.2556 322.4185 70.4991 149.0408 283.1905 183.2630 298.0408 267.8551 520.9595 485.6992 293.0408 463.8577 51.9469 40.4398 56.9565 47.8600 35.7223 41.2122 1339204 1448756_at 3 43.6 cM chr3:90496586-90499210 3 F1 chr3:90496554-90499613 3 F1 RSQ Mm.2128 NM_009114 1 1 20202 S100a9 S100 calcium binding protein A9 (calgranulin B) (S100a9), mRNA. actin cytoskeleton reorganization;; calcium ion binding;; leukocyte chemotaxis;; regulation of integrin biosynthetic process binding ion binding biological regulation;; cellular component organization;; cellular process;; immune system process;; localization;; locomotion;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; behavior;; biosynthetic process;; cell motility;; cell motion;; cellular response to stimulus;; leukocyte migration;; localization of cell;; macromolecule metabolic process;; membrane organization;; organelle organization;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to external stimulus;; taxis 105.3507 107.7913 98.1031 106.3985 91.9400 104.3332 469.8332 501.6035 520.1263 498.0964 509.7324 518.7075 183.5635 252.7038 222.4415 266.3687 266.7800 218.1952 1339365 1448949_at 11 chr11:84778223-84778345 11 C chr11:84771255-84779556 11 C RSQ Mm.1641 NM_007607 1 1 12351 RP23-167D6.1 Car4 carbonic anhydrase 4 (Car4), mRNA. Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] anchored to membrane;; carbonate dehydratase activity;; lyase activity;; membrane;; metal ion binding;; one-carbon metabolic process;; plasma membrane;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 492.6076 421.9979 584.9979 369.7390 347.6533 492.7512 1357.4297 1401.0964 1379.4770 1237.2908 1387.2701 1228.5944 406.0670 661.6726 659.9662 508.1839 638.2004 739.6995 1339476 1449089_at 16 chr16:76291166-76291540 16 C3.1 chr16:76291106-76373294 16 C3.1 RSQ Mm.455873 NM_173440 1 1 268903 Nrip1 nuclear receptor interacting protein 1 (Nrip1), mRNA. histone deacetylase binding;; histone deacetylase complex;; lipid storage;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; ovarian follicle rupture;; ovulation;; protein binding;; receptor activity;; receptor binding;; regulation of transcription, DNA-dependent;; retinoid X receptor binding;; transcription;; transcription corepressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity protein binding;; signal transducer activity;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; biosynthetic process;; cellular metabolic process;; gamete generation;; macromolecule localization;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 198.0844 233.4079 364.4844 238.5533 255.9136 305.8218 205.7295 232.4871 297.7171 290.5964 211.9745 278.9897 71.9942 92.7803 91.8073 64.7201 91.0691 109.3914 1339662 1449311_at 16 C3.3 chr16:87730397-87730943 16 C3.3 UGA Mm.26147 12013 Bach1 BTB and CNC homology 1 (Bach1), mRNA DNA binding;; nucleus;; protein binding;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 93.0771 92.6292 93.8434 107.0607 101.6873 129.9382 131.0401 129.7113 173.8290 157.6806 119.1671 175.1296 57.6538 42.2921 51.3343 52.5747 48.2263 48.3011 1339699 1449360_at 15 43.3 cM chr15:78112991-78113449 15 E1 chr15:78112939-78128810 15 E1 RSQ Mm.1940 NM_007781 1 1 12984 Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) (Csf2rb2), mRNA. Regulation of BAD phosphorylation Apoptosis;; Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] cytokine receptor activity;; cytokine-mediated signaling pathway;; integral to membrane;; membrane;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 31.6518 26.8076 46.0091 38.1997 55.1628 37.9404 64.0725 68.8172 102.0069 86.8801 72.8905 74.4123 43.2876 39.1803 43.6310 48.6262 56.0634 55.9207 1339804 1449484_at 11 chr11:31259509-31260000 11 A4 chr11:31259440-31270061 11 A4 RSQ Mm.32506 NM_011491 1 1 20856 Stc2 stanniocalcin 2 (Stc2), mRNA. extracellular region;; hormone activity extracellular region binding protein binding 2086.4922 2226.2006 2350.4653 2403.8186 2334.4604 2586.7770 1441.2160 1450.5048 700.1195 685.0384 1459.3252 707.7250 300.1185 337.7652 297.3741 419.6539 284.7226 238.2511 1339832 1449519_at 6 chr6:66985453-66985671 6 C1 chr6:66985089-66987401 6 C1 RSQ Mm.389750 NM_007836 1 1 13197 Gadd45a growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), mRNA. ATM Signaling Pathway;; Cell Cycle: G2/M Checkpoint;; p53 Signaling Pathway Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] cell cycle;; cell cycle arrest;; centrosome cycle;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cellular metabolic process;; microtubule-based process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function;; response to stress 136.5044 357.6715 241.1579 157.5509 151.5962 205.6194 69.0098 69.3379 393.3762 400.2617 65.9741 420.8046 59.3971 91.1739 62.6944 48.5173 88.2391 799.8730 1348421 1449526_a_at 7 chr7:133911136-133919078 7 F3 chr7:133909927-133919159 7 F3 RSQ Mm.246881 NM_024228 1 1 68616 Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 (Gdpd3), mRNA. glycerol metabolic process;; glycerophosphodiester phosphodiesterase activity;; hydrolase activity;; integral to membrane;; lipid metabolic process;; membrane;; phosphoric diester hydrolase activity cell;; cell part cell part;; membrane;; membrane part catalytic activity hydrolase activity cellular process;; metabolic process alcohol metabolic process;; cellular metabolic process;; primary metabolic process 51.8347 49.2401 60.5953 60.4990 69.0633 68.4838 108.9853 107.4891 311.8064 219.6831 98.8646 224.5103 108.7865 89.2876 119.3750 119.7721 103.2648 88.0379 1348434 1449590_a_at 9 chr9:99288490-99290204 9 E3.3 chr9:99285838-99337131 9 E3.3 RSQ Mm.2045 NM_008624 1 1 17532 Mras muscle and microspikes RAS (Mras), mRNA. MAPK signaling pathway;; Regulation of actin cytoskeleton CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Tight junction GTP binding;; intracellular;; membrane;; nucleotide binding;; plasma membrane;; small GTPase mediated signal transduction cell;; cell part cell part;; intracellular;; membrane binding nucleotide binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 174.7338 145.7370 251.1434 100.3686 125.8805 133.0624 1344.6797 1323.8787 1586.9702 1638.8643 1305.1138 1640.1318 506.1519 872.1783 751.7369 722.2324 744.6637 522.1836 1348480 1449731_s_at 12 chr12:56590515-56590785 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 45.1782 87.8447 46.0625 39.7298 35.7659 30.0217 629.7926 615.5484 1117.3245 1064.5933 619.4459 1099.8317 359.0207 641.8855 452.1519 380.9297 470.9905 414.3328 1348488 1449773_s_at 10 60.5 cM chr10:80394702-80394906 10 C1 chr10:80392835-80394949 10 C1 RSQ Mm.1360 NM_008655 1 1 17873 Gadd45b growth arrest and DNA-damage-inducible 45 beta (Gadd45b), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 61.1899 73.2986 61.5377 47.3641 48.5596 41.7997 435.5230 427.4124 457.2630 478.9297 400.0377 437.1947 86.9434 103.0473 130.2286 67.9608 81.2033 74.3901 1348516 1449901_a_at 4 chr4:132807657-132808759 4 D2.3 chr4:132796732-132808843 4 D2.3 RSQ Mm.36640 NM_016693 1 1 53608 Map3k6 mitogen-activated protein kinase kinase kinase 6 (Map3k6), mRNA. MAPKinase Signaling Pathway MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] ATP binding;; kinase activity;; magnesium ion binding;; MAP kinase kinase kinase activity;; metal ion binding;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity;; molecular transducer activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 60.8516 55.8777 42.3358 91.1985 92.9370 68.9732 106.6690 107.0012 190.2294 187.8696 126.8132 192.3820 43.9804 39.6582 39.0756 60.6148 42.4420 56.0859 1340074 1449906_at 1 86.6 cM chr1:166074030-166079220 1 H2.2 chr1:166053831-166079876 1 H2.2 RSQ Mm.3337 NM_011347 1 1 20344 Selp selectin, platelet (Selp), mRNA. Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 116.7163 121.5970 129.7632 149.9605 113.8895 145.7075 2117.7220 2040.6052 2205.4019 2228.7374 1991.4544 2285.5771 1021.8277 1266.4219 1060.7164 902.7034 1193.2827 1357.2867 1348544 1449999_a_at 5 4.0 cM chr5:15871609-15876712 5 A2 chr5:15440508-15880329 5 A2 RSQ Mm.159842 NM_001110846 5 1 12293 Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 (Cacna2d1), transcript variant d, mRNA. Cardiac muscle contraction CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Circulatory System; Cardiac muscle contraction [PATH:mmu04260];; MAPK signaling pathway calcium channel activity;; calcium ion binding;; calcium ion transport;; integral to membrane;; ion channel activity;; ion transport;; membrane;; metal ion binding;; protein binding;; regulation of calcium ion transport;; sarcoplasmic reticulum;; T-tubule;; transport;; voltage-gated ion channel activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity biological regulation;; establishment of localization;; localization;; regulation of biological process establishment of localization;; regulation of biological process;; regulation of localization;; transport 177.4174 162.2768 223.5473 133.8947 142.9487 170.8862 165.8920 179.5972 162.2112 160.7909 174.8694 154.1230 58.6620 100.5462 84.0968 63.4364 111.8899 100.4790 1340176 1450051_at X 43.8 cM chrX:103072336-103072892 X D chrX:102992953-103124711 X D RSQ Mm.475674 NM_009530 1 1 22589 RP23-170G19.5 Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) (Atrx), mRNA. ATP binding;; chromatin binding;; DNA binding;; DNA repair;; forebrain development;; helicase activity;; heterochromatin;; hydrolase activity;; metal ion binding;; nuclear chromosome;; nucleic acid binding;; nucleotide binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; sequence-specific DNA binding;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; catalytic activity;; transcription regulator activity chromatin binding;; hydrolase activity;; ion binding;; nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to stress 76.0049 79.1269 68.3399 83.7290 74.3432 73.9998 119.8420 114.0869 478.6041 582.4354 131.5029 535.5104 84.4673 87.3341 90.5160 69.5824 64.6864 79.0687 1340562 1450606_at 11 chr11:98248718-98249320 11 D chr11:98247945-98249411 11 D RSQ Mm.57030 NM_008890 1 1 18948 RP23-355L10.6 Pnmt phenylethanolamine-N-methyltransferase (Pnmt), mRNA. Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Tyrosine metabolism [PATH:mmu00350];; Tyrosine metabolism catecholamine biosynthetic process;; methyltransferase activity;; phenylethanolamine N-methyltransferase activity;; transferase activity catalytic activity transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process 63.1478 63.3205 69.6702 45.0956 71.0036 41.4926 69.8764 74.0638 169.9170 134.2865 81.3791 142.9125 44.4488 49.8159 58.1478 72.9429 46.7535 85.7988 1340700 1450783_at 19 chr19:34724141-34724445 19 C1 chr19:34715378-34724499 19 C1 RSQ Mm.439751 NM_008331 1 1 15957 Ifit1 interferon-induced protein with tetratricopeptide repeats 1 (Ifit1), mRNA. binding binding 231.0152 235.1638 210.2727 233.3274 229.5794 221.7620 947.2199 966.2717 1520.4009 1442.3760 916.3593 1584.7733 606.4323 949.1765 699.3951 620.0904 723.6499 717.6397 1340845 1450971_at 10 60.5 cM chr10:80393047-80394413 10 C1 chr10:80392835-80394949 10 C1 RSQ Mm.1360 NM_008655 1 1 17873 Gadd45b growth arrest and DNA-damage-inducible 45 beta (Gadd45b), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 172.5490 212.0063 185.1447 206.4889 181.9693 231.8699 298.3949 311.5949 389.9536 403.0334 304.7247 363.1381 185.4493 172.5555 173.0195 207.4849 216.4611 272.3849 1341107 1451340_at 1 chr1:36376801-36377288 1 B chr1:36364598-36379820 1 B RSQ Mm.34316 NM_145996 1 1 214855 Arid5a AT rich interactive domain 5A (MRF1-like) (Arid5a), mRNA. DNA binding;; intracellular;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 89.0060 87.0965 119.4480 158.5887 112.0206 143.1864 519.6935 634.6367 820.1534 830.6028 557.1505 739.7736 174.3572 222.4297 163.2715 213.8036 177.6748 169.2024 1341119 1451355_at 4 chr4:86566201-86566728 4 C4 chr4:86520367-86566779 4 C4 RSQ Mm.45019 NM_139306 1 1 230379 RP24-468M3.3 Acer2 alkaline ceramidase 2 (Acer2), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramidase activity;; ceramide metabolic process;; endoplasmic reticulum membrane;; Golgi apparatus;; Golgi membrane;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;; integral to membrane;; lipid metabolic process;; membrane cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity hydrolase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 210.3602 197.4017 261.0369 135.8328 190.9869 265.7619 322.3589 348.6978 356.0557 313.3589 288.6527 358.7005 141.6896 136.2515 115.1924 136.2647 138.0779 158.1350 1341279 1451569_at 6 D1 chr6:92118495-92118956 6 D1 UGA Mm.87062 22026 Nr2c2 CD-1 orphan receptor TAK1 (TAK1) DNA binding;; ligand-dependent nuclear receptor activity;; metal ion binding;; nucleus;; receptor activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; spermatocyte division;; spermatogenesis;; spermatogenesis;; steroid hormone receptor activity;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; reproduction;; reproductive process biosynthetic process;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 73.8615 84.9564 80.7359 96.0136 126.7199 76.4549 1414.2219 1398.2630 1373.3654 1300.9696 1416.4771 1326.1430 429.0317 660.0155 638.8233 567.6845 719.8648 603.9091 1341282 1451577_at 16 B4|16 28.9 cM chr16:43619340-43619721 16 B4 UGA Mm.440824 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 171.3843 350.6214 304.9308 139.6874 165.4960 147.2833 491.4297 469.7440 200.9062 245.3227 450.4501 241.3579 51.8993 43.7403 53.0672 58.3130 60.2290 52.2288 1341305 1451612_at 8 C5|8 45.0 cM chr8:96703143-96703979 8 C5 UGA Mm.192991 17748 Mt1 Metallothionein 1, mRNA (cDNA clone MGC:47147 IMAGE:4990006) cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 55.6164 55.6164 58.3606 49.0425 52.2882 62.2736 351.4852 390.0426 1629.9509 1790.5964 342.2789 1860.1253 229.7631 276.4024 442.2075 129.3800 117.5628 98.9141 1341364 1451715_at 2 91.0 cM chr2:160191130-160191719 2 H2 chr2:160189412-160192801 2 H2 RSQ Mm.330745 NM_010658 1 1 16658 RP23-333A18.1 Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA. brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 104.7092 115.8596 130.8743 90.6181 117.8875 143.2256 715.7394 690.2579 2766.2138 2808.5714 665.3594 2755.7235 652.5212 666.6209 1120.3174 341.1308 278.8834 265.8186 1341365 1451716_at 2 H2|2 91.0 cM chr2:160189869-160190403 2 H2 UG5 Mm.330745 16658 RP23-333A18.1 Mafb V-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 316.2075 301.7815 254.7630 382.2630 369.9297 267.5910 1322.7983 1261.2579 1517.9565 1522.1784 1256.2077 1300.0986 478.7051 504.2193 452.6938 474.1454 547.1144 481.6064 1341390 1451756_at 5 G|5 82.0 cM chr5:148449686-148450062 5 G3 UGA Mm.389712 14254 Flt1 FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) Cytokine-cytokine receptor interaction;; Endocytosis;; Focal adhesion CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] angiogenesis;; ATP binding;; cell differentiation;; cell migration;; identical protein binding;; integral to membrane;; kinase activity;; membrane;; multicellular organismal development;; nucleotide binding;; patterning of blood vessels;; protein amino acid phosphorylation;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway;; vascular endothelial growth factor receptor activity;; vascular endothelial growth factor receptor signaling pathway;; vascular endothelial growth factor receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 62.8092 86.4302 62.9574 80.5540 88.3045 65.1818 112.4378 108.5944 197.3820 258.9297 108.2185 255.3610 112.4359 103.9248 75.5867 111.6237 105.2096 113.8202 1341465 1451883_at 3 A2|3 chr3:19586092-19586509 3 A2 UGA Mm.450006 620316 BC002189 CDNA sequence BC002189, mRNA (cDNA clone MGC:7386 IMAGE:3487872) 174.7075 194.2976 168.3633 191.7630 201.2603 179.0147 189.5102 180.6369 318.8186 289.6106 206.4570 287.8437 157.1592 124.7498 155.3500 120.6901 120.7692 126.6341 1341577 1452082_at 8 E1 chr8:122685928-122686463 8 E1 UGA Mm.101958 234797 6430548M08Rik RIKEN cDNA 6430548M08 gene, mRNA (cDNA clone MGC:38801 IMAGE:5359842) 155.5891 150.1723 147.4574 142.8460 122.9580 131.4506 289.9633 248.6664 489.4047 411.5800 262.6519 436.7554 186.2721 178.5379 182.5308 208.8824 253.1714 213.8972 1341738 1452282_at 8 chr8:75018537-75019040 8 B3.3 chr8:75018459-75072169 8 B3.3 RSQ Mm.235885 NM_027485 1 1 70625 Med26 mediator complex subunit 26 (Med26), mRNA. DNA binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 20.7282 36.6882 37.5928 17.6859 32.0905 16.2314 1043.0394 1148.4852 738.8005 994.1236 991.3447 922.4468 380.7794 382.8844 528.7865 348.7193 321.1248 262.9268 1349242 1452349_x_at 1 chr1:175826485-175843053 1 H3 RSQ Mm.476726 NM_001033450 2 2 381308 Mnda myeloid cell nuclear differentiation antigen (Mnda), mRNA. 183.0529 199.3523 464.2227 101.2332 177.4147 208.0176 390.8001 356.5885 416.6645 432.9441 335.1519 433.9074 185.7766 225.8013 219.1797 144.0691 213.9596 168.7820 1341817 1452378_at 19A chr19:5800663-5801120 19 A chr19:5795689-5802671 19 A RSQ NR_002847 1 1 72289 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA. 568.1926 817.2132 588.2363 345.3456 619.5973 563.9251 1541.3642 1547.7487 2454.4382 2474.0116 1611.6091 2276.4843 468.7530 571.9240 580.5158 452.2785 592.9019 585.0964 1341848 1452418_at 1 chr1:9226200-9228974 1 A2 RSQ XM_001472850 5 3 100039464 LOC100039464 PREDICTED: similar to gag protein, transcript variant 1 (LOC100039464), mRNA. 219.1668 235.3468 279.7972 164.6145 188.2483 164.6550 1353.7991 1394.0735 1369.7070 1305.6663 1320.7487 1303.6650 465.7838 354.1816 540.6219 419.4297 461.6294 445.5274 1349296 1452519_a_at 7 10.2 cM chr7:29161986-29162456 7 A3 chr7:29161802-29164247 7 A3 RSQ Mm.389856 NM_011756 1 1 22695 Zfp36 zinc finger protein 36 (Zfp36), mRNA. AU-rich element binding;; cytoplasm;; cytosol;; cytosol;; DNA binding;; metal ion binding;; mRNA binding;; mRNA binding;; mRNA catabolic process;; negative regulation of inflammatory response;; negative regulation of myeloid cell differentiation;; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;; nuclear-transcribed mRNA poly(A) tail shortening;; nucleic acid binding;; nucleus;; protein kinase cascade;; regulation of mRNA stability;; RNA destabilization;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of response to stimulus;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; response to external stimulus;; response to stress 465.8732 521.7821 470.1536 277.4740 464.6486 522.3174 1570.6307 1570.7863 2186.3064 1989.7729 1552.2630 1988.7766 493.3344 888.6739 780.3327 454.0406 690.8022 420.7867 1349404 1453238_s_at 11 chr11:86626266-86629631 11 C RSQ NR_002860 11 10 319269 A130040M12Rik RIKEN cDNA A130040M12 gene (A130040M12Rik), non-coding RNA. 97.7738 99.3304 84.3428 83.9229 88.0449 92.5321 1946.8686 1970.2910 3062.8135 3181.6947 1969.7860 3208.7820 1634.7309 1067.5408 898.5303 884.3114 570.5846 532.9160 1349481 1453851_a_at 13 chr13:51943246-51943781 13 A5 chr13:51942063-51943844 13 A5 RSQ Mm.281298 NM_011817 1 1 23882 Gadd45g growth arrest and DNA-damage-inducible 45 gamma (Gadd45g), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; interferon-gamma biosynthetic process;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; T-helper 1 cell differentiation cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; cytokine production;; immune response;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 261.1374 280.7843 316.1650 148.5960 187.8941 209.5635 197.8081 188.4278 290.9886 255.9993 190.4939 290.4121 112.4853 91.4219 118.8125 79.9956 141.2901 132.3801 1342222 1454030_at 19 A chr19:3477831-3478364 19 A UGA Mm.284686 52036 Saps3 SAPS domain family, member 3 (Saps3), mRNA cytoplasm;; nucleus;; protein phosphatase binding;; regulation of phosphoprotein phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cellular metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 55.5191 56.9334 51.8443 57.9646 54.4747 55.4703 240.0356 270.2989 326.4548 328.7063 260.0346 317.1519 111.0687 135.9329 103.2924 115.6685 125.8989 100.4656 1349517 1454037_a_at 5 82.0 cM chr5:148466686-148485183 5 G3 chr5:148373771-148537564 5 G3 RSQ Mm.389712 NM_010228 1 1 14254 Flt1 FMS-like tyrosine kinase 1 (Flt1), mRNA. Cytokine-cytokine receptor interaction;; Endocytosis;; Focal adhesion CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] angiogenesis;; ATP binding;; cell differentiation;; cell migration;; identical protein binding;; integral to membrane;; kinase activity;; membrane;; multicellular organismal development;; nucleotide binding;; patterning of blood vessels;; protein amino acid phosphorylation;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway;; vascular endothelial growth factor receptor activity;; vascular endothelial growth factor receptor signaling pathway;; vascular endothelial growth factor receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 4707.9487 4429.0510 5154.3189 5292.9181 7748.5524 4456.2118 22.9533 20.3788 57.4732 44.0718 18.4784 41.3349 16.1563 16.7283 11.7841 38.0734 41.0757 14.6605 1349572 1454608_x_at 18 7.0 cM chr18:20832268-20832377 18 A2 chr18:20823913-20832820 18 A2 RSQ Mm.2108 NM_013697 1 1 22139 Ttr transthyretin (Ttr), mRNA. extracellular region;; hormone activity;; thyroid hormone generation;; transport extracellular region binding protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; hormone metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological quality;; transport 489.5551 358.4544 492.8005 286.3250 237.3763 280.4460 432.4445 449.9297 901.7931 860.0940 427.3303 908.3186 402.0770 429.9424 435.5353 409.6664 352.0807 358.9929 1342410 1455220_at 19 37.6 cM chr19:41920549-41921065 19 C3 chr19:41920467-41922622 19 C3 RSQ Mm.222723 NM_177603 1 1 212398 Frat2 frequently rearranged in advanced T-cell lymphomas 2 (Frat2), mRNA. Wnt signaling pathway CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Wnt receptor signaling pathway;; Wnt receptor signaling pathway biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 180.0056 154.9201 168.4422 184.0496 205.6186 154.8569 323.9602 308.2770 1664.2896 1416.2154 321.4307 1466.3313 469.9297 420.6888 500.4297 485.9151 410.1359 355.7149 1342536 1455869_at 11 chr11:5908951-5909394 11 A1 UGA Mm.458283 Transcribed locus, moderately similar to XP_001477892.1 PREDICTED: hypothetical protein [Mus musculus] 22.6423 20.6528 36.1766 242.2528 152.9323 183.5801 3532.9631 3291.2873 758.4727 901.1034 3378.5646 879.0435 175.8772 212.4538 268.9634 380.5947 288.2147 403.0422 1349775 1455899_x_at 11 chr11:117827463-117827587 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 191.5989 191.7354 280.4391 123.6240 126.7520 175.1678 763.4848 831.3570 564.8040 648.9737 798.5396 637.9292 306.8997 297.5614 299.8175 355.6544 325.9099 306.1279 1349776 1455900_x_at 2 89.0 cM chr2:157942148-157942327 2 H1 IPA Tgm2 transglutaminase 2, C polypeptide 3651.6992 3470.0276 4154.1246 4593.5087 6869.2908 3762.0437 10.0928 8.9278 24.0086 26.5427 11.9452 20.2236 10.4789 10.9173 8.7860 25.0619 18.3032 12.0530 1349780 1455913_x_at 18 7.0 cM chr18:20832283-20832379 18 A2 chr18:20823913-20832820 18 A2 RSQ Mm.2108 NM_013697 1 1 22139 Ttr transthyretin (Ttr), mRNA. extracellular region;; hormone activity;; thyroid hormone generation;; transport extracellular region binding protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; hormone metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological quality;; transport 224.3789 293.8743 292.4814 158.7007 212.8118 196.3393 495.1080 513.8144 543.4584 568.1414 476.9691 596.1502 197.4433 196.1357 215.3183 203.9973 281.0947 288.8881 1342572 1456048_at 19 chr19:37097475-37097933 19 C2 chr19:37095780-37281783 19 C2 RSQ Mm.391176 NM_198300 1 1 208922 Cpeb3 cytoplasmic polyadenylation element binding protein 3 (Cpeb3), mRNA. nucleic acid binding;; nucleotide binding;; RNA binding binding nucleic acid binding;; nucleotide binding 859.1519 650.8928 1018.3011 557.1929 486.6907 770.0773 739.8303 711.0898 728.9508 697.6797 698.7794 718.0816 245.0972 349.4830 331.9656 230.7311 472.7760 448.7201 1342585 1456112_at 1 chr1:152260120-152261656 1 G1 chr1:152239982-152297059 1 G1 RSQ Mm.174256 NM_133780 2 2 108989 Tpr translocated promoter region (Tpr), mRNA. Pathways in cancer;; Thyroid cancer CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Thyroid Cancer [PATH:mmu05216] nuclear envelope cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle envelope;; organelle part 112.8146 105.8140 138.5235 73.5831 89.5893 156.0188 137.9994 133.9308 149.0025 140.8181 131.9066 132.5810 61.0791 51.4573 76.0630 52.5729 80.1340 82.7404 1342588 1456120_at 2 chr2:125578627-125586066 2 F1 chr2:125562721-125608606 2 F1 RSQ Mm.138091 NM_177608 1 1 70354 RP23-367K9.1 Secisbp2l SECIS binding protein 2-like (Secisbp2l), mRNA. 48.9595 27.6735 54.1104 297.7746 226.1876 240.6310 2547.2819 2516.3176 501.8186 599.3431 2565.6128 644.3749 154.3001 149.3006 177.7507 288.0805 200.8621 249.8199 1349871 1456212_x_at 11 E2 chr11:117827490-117827770 11 E2 IPA Mm.3468 Socs3 Suppressor of cytokine signaling 3 (Socs3), mRNA 284.2346 346.9052 420.5004 210.4917 316.1036 360.5706 345.8950 333.9957 355.6241 317.8186 349.3186 347.0434 146.9297 155.7967 167.7478 143.7622 184.9645 229.9045 1342601 1456262_at 9 F1 chr9:107662081-107662640 9 F1 UGA Mm.259197 83486 Rbm5 RNA binding motif protein 5 (Rbm5), mRNA apoptosis;; intracellular;; metal ion binding;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus;; RNA binding;; RNA splicing;; spliceosomal complex;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding ion binding;; nucleic acid binding;; nucleotide binding cellular process;; death;; metabolic process cell death;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 58.2582 75.8301 59.6129 70.2473 60.2035 61.0125 208.0730 213.4019 245.6717 257.8630 206.8505 227.4618 67.3618 77.4053 73.8422 68.1122 71.9474 92.0111 1342688 1457147_at 2 A3 chr2:20724458-20725017 2 A3 UGA Mm.237935 208618 RP23-436G18.1 Etl4 Enhancer trap locus 4, mRNA (cDNA clone IMAGE:4988846) cytoplasm;; embryonic skeletal system development;; multicellular organismal development cell;; cell part cell part;; intracellular;; intracellular part developmental process;; multicellular organismal process anatomical structure development;; embryonic development;; multicellular organismal development 260.1930 345.3605 387.6799 195.1352 233.6136 359.2630 164.0199 157.2314 191.3709 175.2338 166.1199 163.9016 74.3027 76.0777 115.4933 88.6920 127.7925 118.3553 1342758 1459917_at 11 C chr11:84682500-84682776 11 C UGA Mm.356653 217039 RP23-293L24.5 Ggnbp2 Gametogenetin binding protein 2 (Ggnbp2), mRNA cell differentiation;; cytoplasm;; cytoplasmic vesicle;; multicellular organismal development;; nucleus;; protein binding;; spermatogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; vesicle binding protein binding cellular process;; developmental process;; multicellular organismal process;; reproduction;; reproductive process cellular developmental process;; gamete generation;; multicellular organismal development;; reproductive process;; sexual reproduction 14.4869 17.3079 16.7488 20.1820 21.1273 14.2251 169.3280 186.2567 257.4448 227.3657 185.7142 216.2200 21.4183 48.0411 51.2702 40.9233 51.9237 33.3449 1342983 1460417_at 6 chr6:31115507-31168433 6 A3.3 RSQ XR_035177 2 1 232685 AB041803 PREDICTED: cDNA sequence AB041803 (AB041803), misc RNA. 29.2075 36.4877 37.0521 40.3219 39.3502 34.3982 809.1483 836.9576 948.9401 1019.0270 830.6730 948.8652 337.6056 557.8939 380.7155 349.4893 375.8326 486.0467 1342988 1460426_at 3 F2.2|3 51.5 cM chr3:97550660-97557001 3 F2.2 UGA Mm.129840 83679 Pde4dip Phosphodiesterase 4D interacting protein (myomegalin), mRNA (cDNA clone IMAGE:4954590) cytoplasm;; Golgi apparatus;; nucleus;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding 244.7028 499.5748 134.5647 341.1133 401.3741 246.8835 249.1946 279.8767 279.4220 282.6819 280.6690 257.7376 79.5299 77.8648 68.7668 83.2745 69.1519 74.9461 1343058 1460670_at 18 3.0 cM chr18:12314622-12314869 18 A1 chr18:12287358-12315876 18 A1 RSQ Mm.28551 NM_024182 1 1 66878 Riok3 RIO kinase 3 (yeast) (Riok3), mRNA. ATP binding;; catalytic activity;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 13.5832 11.8043 10.2154 12.6693 12.3762 12.7614 157.4279 160.8017 131.1863 89.3335 171.8950 101.9436 21.4183 47.1964 34.6039 37.5507 31.6839 29.9369 1370809 1420312_s_at IPA Unknown 162.6124 151.8905 163.9779 119.8749 97.5051 144.3770 721.2315 703.3000 1895.7038 1694.9889 714.5902 1660.2075 408.8358 536.3186 384.5423 243.2002 335.2188 213.8707 1350443 1428352_at 8 chr8:73359362-73359595 8 B3.3 chr8:73359036-73363619 8 B3.3 RSQ Mm.24215 NM_027560 1 1 70807 Arrdc2 arrestin domain containing 2 (Arrdc2), mRNA. 101.3781 96.5053 88.5922 117.8785 108.9330 89.3072 153.9090 157.1749 240.8718 233.6675 170.2644 267.0862 108.5442 99.3836 127.4213 83.2453 82.1998 112.4579 1350669 1428731_at 14 chr14:21368304-21368700 14 A3 chr14:21368133-21437576 14 A3 RSQ Mm.301173 NM_030180 1 1 78787 Usp54 ubiquitin specific peptidase 54 (Usp54), mRNA. ubiquitin thiolesterase activity;; ubiquitin-dependent protein catabolic process catalytic activity hydrolase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 842.3583 963.8451 670.3741 548.2662 472.4595 575.5695 2651.2744 2589.4455 3148.0404 2907.2683 2539.6318 2792.3091 1353.3186 1408.5972 1270.7445 1115.3331 1108.1391 1272.8304 1351041 1429300_at 12 chr12:112214932-112215222 12 F1 chr12:112213562-112217231 12 F1 RSQ Mm.250989 NM_175207 1 1 74251 Ankrd9 ankyrin repeat domain 9 (Ankrd9), mRNA. hydrolase activity catalytic activity hydrolase activity 66.1762 59.6197 72.4504 52.8276 101.1535 67.0577 221.0408 261.7268 461.0890 463.9440 294.5933 455.9455 162.4676 201.0886 193.5748 164.8741 191.9621 132.3947 1351107 1429399_at 18 A2 chr18:21141785-21142262 18 A2 UGA Mm.45980 67664 Rnf125 Rnf125 mRNA for RNF125 protein immune response;; intracellular;; ligase activity;; metal ion binding;; modification-dependent protein catabolic process;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; immune system process;; metabolic process;; response to stimulus catabolic process;; cellular metabolic process;; immune response;; macromolecule metabolic process;; primary metabolic process 379.4510 376.6604 558.8814 264.2938 346.8186 424.4597 770.8939 816.5641 708.0265 742.2007 783.4769 711.3937 210.9011 355.9297 375.2283 331.2824 460.8672 368.0517 1351133 1429433_at 1 chr1:164650697-164670489 1 H2.1 chr1:164601915-164670687 1 H2.1 RSQ Mm.245446 NM_001081290 1 1 226562 Bat2d BAT2 domain containing 1 (Bat2d), mRNA. 97.6583 117.8026 117.2562 99.0711 90.8841 143.8826 389.3519 353.3611 355.7728 508.9285 329.3600 391.4466 195.2738 207.4147 188.5620 226.6747 286.0352 200.2654 1351390 1429796_at 16 B3 chr16:34013284-34014058 16 B3 IPA 2210407G14Rik RIKEN cDNA 2210407G14 gene 95.8427 107.7155 78.6651 89.7094 115.0035 107.0407 415.6009 423.8385 520.6564 410.3654 418.5605 427.7243 204.0964 235.2404 225.1735 211.4381 234.0885 204.4533 1351428 1429843_at 4 chr4:133807078-133807598 4 D3 chr4:133807024-133810021 4 D3 RSQ Mm.100168 NM_001099296 1 1 72690 RP23-354H24.7 Grrp1 glycine/arginine rich protein 1 (Grrp1), mRNA. 48.9827 61.7070 46.1552 36.9735 49.4715 47.9587 350.0629 369.2184 425.2374 360.2150 348.2867 356.5794 74.0493 95.1920 110.5775 147.6102 135.4853 103.3945 1351449 1429870_at 3 A3 chr3:28259219-28259607 3 A3 UG5 Mm.126193 665113 Tnik TRAF2 and NCK interacting kinase, mRNA (cDNA clone MGC:183916 IMAGE:9087916) ATP binding;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; small GTPase regulator activity;; transferase activity binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleoside-triphosphatase regulator activity;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 92.4790 98.0733 132.6410 39.4033 77.6103 115.1773 412.5408 424.7002 428.0360 417.3065 393.4852 423.6519 87.5274 129.9532 136.8044 89.0096 183.1321 211.6079 1351460 1429882_at 8 UGA Mm.440442 Transcribed locus, strongly similar to NP_001004371.1 cadherin 11, type 2, OB-cadherin (osteoblast) [Gallus gallus] 62.9501 71.3673 79.0129 72.9773 73.8303 63.9327 377.5964 393.5751 442.4852 395.3363 398.8618 411.0854 156.9686 207.5717 211.9575 224.1706 232.6301 184.6745 1351585 1430043_at 11 chr11:62095536-62096022 11 B2 chr11:62094974-62096109 11 B2 RSQ Mm.477526 NM_029704 1 1 72795 RP23-330N10.4 Ttc19 tetratricopeptide repeat domain 19 (Ttc19), transcript variant 2, mRNA. binding binding 86.5712 109.6886 85.5747 89.8892 71.2699 125.3745 86.1568 102.9556 126.4259 125.8538 99.2547 138.9115 40.7640 48.6123 55.8235 55.7944 86.2441 72.5892 1351678 1430152_at chr4:108997995-108998478 4 C7 IPA ESTs 17.0275 16.9106 19.9746 17.9895 18.6048 21.7383 163.3294 172.5743 314.2027 376.0961 179.3186 358.6830 32.9315 33.8547 50.4968 58.2947 53.2984 30.0474 1351838 1430352_at 6 D1 chr6:92795416-92795850 6 D1 UGA Mm.257557 101401 mCG_142056 Adamts9 MKIAA1312 protein endopeptidase activity;; extracellular space;; metallopeptidase activity;; positive regulation of melanocyte differentiation;; proteinaceous extracellular matrix;; proteolysis;; proteolysis;; regulation of pigmentation during development extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; pigmentation;; positive regulation of biological process;; regulation of biological process catabolic process;; cellular developmental process;; macromolecule metabolic process;; pigmentation during development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 91.6713 112.8285 113.9650 79.0010 84.9650 84.5784 146.5877 150.8532 94.2258 88.9107 147.7075 86.6798 50.5080 41.9464 38.2963 39.4089 51.0285 47.2845 1351845 1430362_at chr19:40547310-40547726 19 C3 IPA 5730409N24Rik RIKEN cDNA 5730409N24 gene 37.8564 43.6146 30.6882 41.1261 40.6373 32.5740 131.6784 107.2894 185.5672 155.8225 98.2072 168.6519 57.2162 65.1021 58.6593 67.5937 68.6733 71.4657 1351932 1430470_at 18 E1 chr18:61695210-61695524 18 E1 UGA Mm.234681 328967 4933429F08Rik Hypothetical protein cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; protein binding;; regulation of Rho protein signal transduction;; Rho guanyl-nucleotide exchange factor activity cell;; cell part cell part;; intracellular;; intracellular part binding;; enzyme regulator activity nucleoside-triphosphatase regulator activity;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 53.7058 59.7245 65.8944 54.5735 45.6945 44.0247 115.4007 100.5551 131.8270 148.5959 96.9803 99.8584 38.0715 36.5450 49.5431 49.7839 51.6039 45.2680 1352062 1430646_at 14 chr14:120800227-120800737 14 E4 IPA 5830407P18Rik RIKEN cDNA 5830407P18 gene 40.2846 40.6349 38.3488 59.8010 43.8537 40.3322 109.8771 123.5250 204.5408 181.0259 107.9115 140.9264 71.5845 98.0169 66.7843 59.4835 58.8083 72.5135 1352278 1430928_at chr19:20658957-20659524 19 B IPA 2900002J02Rik RIKEN cDNA 2900002J02 gene 23.8974 34.0393 32.7923 23.0065 33.1597 32.8906 53.4093 49.7190 51.3859 55.1204 40.3617 71.3777 20.1391 29.0999 38.1653 39.8278 39.5960 27.6749 1352317 1430969_at 2 E1 chr2:90687892-90688410 2 E1 UG5 Mm.28023 56428 RP23-147D3.1 Mtch2 Mitochondrial carrier homolog 2 (C. elegans), mRNA (cDNA clone MGC:49067 IMAGE:5323415) integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part establishment of localization;; localization establishment of localization;; transport 178.4016 192.8401 204.7630 199.7812 200.3986 186.5408 102.8966 89.5201 147.2087 158.3059 88.3568 147.2515 75.7915 62.8036 39.6774 67.1627 78.8259 86.7130 1352574 1431399_at 6 chr6:92876126-92887367 6 D1 UG5 Mm.158235 Transcribed locus, moderately similar to NP_891550.1 ADAM metallopeptidase with thrombospondin type 1 motif, 9 preproprotein [Homo sapiens] 36.5669 34.1892 34.2516 41.4322 41.6775 34.9320 31.3186 35.9796 84.3463 74.2800 39.9359 84.2294 27.7300 22.3955 27.0462 21.7037 20.2123 32.8104 1353251 1432461_at 10 chr10:22889870-22905127 10 A3 UGA Mm.444786 Transcribed locus 36.8534 45.4393 35.7931 41.6602 48.6893 52.8871 81.3256 82.4758 137.8102 117.6162 80.4278 117.2482 26.5770 36.9735 44.4520 29.3253 36.5566 41.7785 1353415 1432665_at chr13:110437515-110438024 13 D2.2 IPA 2210416J07Rik RIKEN cDNA 2210416J07 gene 128.0997 132.3975 135.4853 146.8518 153.0756 89.0166 1834.2010 1780.4161 1074.4042 1079.5964 1640.9575 1002.9459 129.7008 182.8163 168.3064 189.6256 260.8673 176.7876 1353873 1433148_at chr7:137797332-137797814 7 F3 IPA 4930513N20Rik RIKEN cDNA 4930513N20 gene 778.7252 707.7408 1060.2075 414.6353 424.3186 493.8186 2908.2019 2883.9926 3611.5964 3169.7510 3032.4237 3353.2092 952.8688 1145.3616 1426.4220 885.3391 1122.8809 694.1395 1354215 1433634_at 8 chr8:129114739-129115115 8 E2 chr8:129112193-129117336 8 E2 RSQ Mm.334918 XM_284454 2 1 270110 Irf2bp2 PREDICTED: interferon regulatory factor 2 binding protein 2, transcript variant 1 (Irf2bp2), mRNA. negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 180.1815 219.3638 190.1035 207.3017 192.5549 183.1387 842.2075 803.8823 988.7115 1066.1241 765.5954 949.8691 475.1168 555.5922 434.5366 398.9852 501.3570 349.1519 1354318 1433837_at 6 chr6:116602283-116602563 6 E3 chr6:116600716-116602812 6 E3 RSQ Mm.38231 NM_145980 1 1 213393 8430408G22Rik RIKEN cDNA 8430408G22 gene (8430408G22Rik), mRNA. 24.9572 26.5868 24.5720 26.2727 22.1048 21.1883 700.8431 719.2352 779.4604 807.8426 784.4297 753.6875 84.6976 188.8789 228.8203 75.8925 102.0345 93.8107 1371171 1434202_a_at 14 A1 chr14:9128859-9128932 14 A1 UGA Mm.256058 268709 Fam107a Family with sequence similarity 107, member A (Fam107a), mRNA 55.1859 65.1166 64.5100 54.1319 47.0990 49.1724 65.0441 75.6065 104.3742 80.2214 68.0535 104.8365 42.7094 44.5490 53.1875 43.0502 53.2507 57.8837 1354515 1434208_at 7 E1 chr7:107071073-107071571 7 E2 UGA Mm.323087 108937 Rnf169 MKIAA1991 protein 180.2269 217.4666 202.4442 200.4990 197.2148 169.3741 477.1519 439.0444 408.1550 374.8653 383.4660 435.2250 194.3700 198.3156 186.0997 192.9852 228.1720 227.8985 1354583 1434350_at 9 chr9:119880327-119880851 9 F4 chr9:119880283-119893776 9 F4 RSQ Mm.477982 NM_153287 1 1 215418 Csrnp1 cysteine-serine-rich nuclear protein 1 (Csrnp1), mRNA. apoptosis;; DNA binding;; face morphogenesis;; nucleus;; palate development;; platelet-derived growth factor receptor signaling pathway;; positive regulation of transcription from RNA polymerase II promoter;; post-embryonic development;; regulation of transcription, DNA-dependent;; skeletal system morphogenesis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell death;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; post-embryonic development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 87.8086 65.1972 86.4824 76.0160 106.6344 64.5530 377.9666 354.8741 563.5770 577.4852 380.6602 580.6843 225.5258 257.7287 232.9203 241.3803 251.6568 209.2081 1354973 1435084_at 18 chr18:21145335-21145848 18 A2 UGA Mm.475404 Transcribed locus 16.5836 16.0701 12.6378 13.1258 13.6265 12.0047 207.4297 208.1106 259.2286 274.6490 207.4490 268.2120 88.2933 143.3830 132.1716 100.4872 83.4510 72.2200 1354998 1435125_at 12 chr12:104432850-104433264 12 E UG5 Mm.427936 Transcribed locus 179.9234 195.8523 430.0894 115.3756 177.5488 287.1080 377.3464 364.7956 413.2489 417.2527 347.3133 394.7778 130.1712 144.4473 162.9311 144.7630 233.2943 222.4442 1355019 1435163_at 17 chr17:32910266-32910799 17 B1 chr17:32902126-32925232 17 B1 RSQ Mm.38813 NM_172458 1 1 208292 Zfp871 zinc finger protein 871 (Zfp871), mRNA. metal ion binding;; nucleus;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 13.2266 18.5048 17.3714 17.4616 14.6068 15.8664 150.3186 157.9297 135.5040 155.7110 173.0408 152.4115 16.3269 14.7692 13.4244 16.3376 17.4830 15.7107 1355275 1435579_at 4 UG5 Mm.427140 Transcribed locus 43.8745 47.6467 47.9430 45.0468 42.7186 47.1873 122.4483 102.1966 181.0734 147.4729 116.8127 143.5593 57.0160 55.9218 98.0122 55.8059 49.3603 55.0942 1355354 1435694_at 18 chr18:39535346-39535896 18 B3 chr18:39152798-39535939 18 B3 RSQ Mm.329396 NM_175164 1 1 71302 Arhgap26 Rho GTPase activating protein 26 (Arhgap26), mRNA. cell junction;; cytoplasm;; cytoskeleton;; GTPase activator activity;; intracellular;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle enzyme regulator activity enzyme activator activity;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 26.3831 33.6537 28.2770 31.8946 28.1423 21.0219 61.6073 49.9463 43.3778 69.0697 46.7772 59.2464 20.9977 27.6490 29.9093 16.9342 18.8200 21.6851 1355485 1435918_at 14 A1 chr14:9130098-9130562 14 A1 UG5 Mm.256058 268709 Fam107a Family with sequence similarity 107, member A (Fam107a), mRNA 456.7491 654.4313 639.5929 491.9224 303.9814 408.1379 799.1938 780.8251 1027.4622 950.5746 746.5896 990.8159 436.4683 420.9232 487.3028 333.4076 321.1290 341.3507 1355678 1436202_at 19A chr19:5795727-5796151 19 A chr19:5795689-5802671 19 A RSQ NR_002847 1 1 72289 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA. 256.9180 278.0716 103.3555 129.7635 99.8319 21.8778 143.6850 168.6241 91.4617 80.1248 161.5300 92.2553 17.4268 21.8343 13.6373 245.0792 288.3497 18.7845 1355703 1436240_at 6 chr6:49206477-49206881 6 B2.3 UGA Mm.461284 Transcribed locus 157.4663 171.3502 133.1388 182.2765 172.6192 151.3599 1320.0476 1369.1028 1439.1308 1208.2967 1370.4752 1258.4813 476.4218 720.8686 568.8199 589.0487 800.3278 734.9672 1356154 1437066_at 16 B4|16 28.9 cM chr16:43638539-43639055 16 B4 UGA Mm.136238 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone IMAGE:6484816) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 104.8243 147.2898 162.7146 155.6297 134.8152 117.4897 241.9925 280.4297 270.5834 272.5219 252.9257 283.9297 89.6233 133.7463 99.4189 92.3813 79.5893 110.4748 1356345 1437410_at 5 F-G1 chr5:122021168-122021702 5 F UGA Mm.284446 11669 Aldh2 Aldehyde dehydrogenase 2, mitochondrial, mRNA (cDNA clone MGC:6764 IMAGE:3600875) 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation aldehyde dehydrogenase (NAD) activity;; metabolic process;; mitochondrion;; oxidation reduction;; oxidoreductase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity oxidoreductase activity metabolic process oxidation reduction 42.8310 41.5959 35.0814 45.6915 40.0063 42.6221 146.8320 146.7885 124.7044 120.1719 157.9181 125.0044 58.1335 57.9286 45.7317 46.0129 36.5453 47.5652 1356438 1437584_at 17 chr17:47656286-47656414 17 C UGA Mm.453308 Transcribed locus 137.1203 164.3425 178.1853 96.8368 136.2450 115.5263 178.3563 174.5084 181.4579 167.1271 177.8324 177.9079 55.7771 78.2885 75.5490 68.6307 86.1956 82.4230 1356463 1437638_at 17 chr17:23950981-23951487 17 A3.3 UGA Mm.436876 Transcribed locus, strongly similar to NP_780438.2 serine/arginine repetitive matrix 2 [Mus musculus] 24.8281 23.7040 20.7054 22.4720 24.7504 28.3153 108.4330 121.6541 105.1954 132.6316 108.5970 120.1537 40.4244 43.2499 48.5488 44.1927 41.3511 42.8751 1356486 1437676_at 11 C chr11:93911380-93911961 11 D UG5 Mm.260737 70834 RP23-378I13.3 Spag9 JNK-associated leucine-zipper protein activation of MAPK activity;; cytoplasm;; JUN kinase binding;; kinesin binding;; protein homooligomerization cell;; cell part cell part;; intracellular;; intracellular part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular component assembly;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 333.7450 308.0419 379.8517 309.8613 229.8451 339.5648 684.1270 783.3072 779.0014 790.6519 721.2501 720.8822 328.5184 394.7576 357.8731 310.2089 313.9490 367.9784 1356511 1437745_at 4 1.0 cM chr4:8679995-8712728 4 A1 chr4:8618067-8793957 4 A1 RSQ Mm.138792 NM_001081417 1 1 320790 RP23-464N23.1 Chd7 chromodomain helicase DNA binding protein 7 (Chd7), mRNA. adult heart development;; adult walking behavior;; ATP binding;; ATP-dependent helicase activity;; blood circulation;; blood vessel development;; camera-type eye development;; chromatin;; chromatin assembly or disassembly;; chromatin binding;; chromatin modification;; DNA binding;; ear morphogenesis;; embryonic hindlimb morphogenesis;; female genitalia development;; heart morphogenesis;; helicase activity;; hydrolase activity;; in utero embryonic development;; inner ear morphogenesis;; locomotory behavior;; nose development;; nucleic acid binding;; nucleotide binding;; nucleus;; palate development;; positive regulation of multicellular organism growth;; regulation of transcription, DNA-dependent;; sensory perception of sound;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; catalytic activity chromatin binding;; hydrolase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus adult behavior;; anatomical structure development;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of growth;; positive regulation of multicellular organismal process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; system process 193.9555 259.5078 241.0057 250.0332 251.1647 172.6513 365.8843 378.4633 549.9189 502.4428 335.2207 578.5162 246.4433 225.2063 296.3259 297.1936 345.0221 250.1040 1356537 1437785_at 6 chr6:92722910-92723268 6 D1 chr6:92722692-92851435 6 D1 RSQ Mm.257557 NM_175314 1 1 101401 mCG_142056 Adamts9 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 (Adamts9), mRNA. endopeptidase activity;; extracellular space;; metallopeptidase activity;; positive regulation of melanocyte differentiation;; proteinaceous extracellular matrix;; proteolysis;; proteolysis;; regulation of pigmentation during development extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; pigmentation;; positive regulation of biological process;; regulation of biological process catabolic process;; cellular developmental process;; macromolecule metabolic process;; pigmentation during development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 113.2163 113.1530 104.3753 74.6845 93.6783 107.4891 302.5165 271.0408 241.5616 238.8618 277.1673 253.0334 95.2203 87.3523 134.0364 96.9872 129.5435 115.0347 1356556 1437821_at chr18:38032193-38032756 18 B3 IPA Mus musculus 7 days embryo whole body cDNA, RIKEN full-length enriched library, clone:C430005H19 product:unknown EST, full insert sequence. 653.0678 865.0790 830.0233 376.9137 539.4318 550.4516 600.6927 632.6344 614.0041 631.9723 584.4969 611.5086 241.2458 335.0650 303.7405 287.8759 414.8943 395.7687 1356570 1437862_at 12 D1 chr12:85004241-85004781 12 D1 UGA Mm.46005 67039 Rbm25 RNA binding motif protein 25 (Rbm25), mRNA cytoplasm;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding;; nucleotide binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 247.7614 278.9993 259.4355 263.9639 288.6008 247.6447 835.8576 789.2137 527.7630 507.7075 720.4744 543.3741 179.5772 129.7851 134.6100 122.8249 143.6006 174.2888 1356604 1437916_at 7 chr7:71051764-71051840 7 C UGA Mm.446212 Transcribed locus 94.5979 95.4525 131.5848 69.2452 109.2084 57.0676 74.3814 82.0409 109.7762 95.8878 82.1029 82.4238 46.7740 50.9592 40.4182 40.1099 45.1789 62.7388 1356620 1437941_at X F3-F4|X 72.0 cM UGA Mm.350712 110094 RP23-181L15.3 Phka2 CDNA clone IMAGE:40051010 Calcium signaling pathway;; Insulin signaling pathway CLASS Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] calmodulin binding;; carbohydrate metabolic process;; glycogen metabolic process;; kinase activity;; membrane;; plasma membrane cell;; cell part cell part;; membrane binding;; catalytic activity protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 3441.6536 2949.5470 4427.8859 2616.2846 2993.5846 3477.7558 1713.8843 1705.9656 1760.6113 1688.1422 1711.3184 1704.0489 500.2920 974.9365 618.8171 569.3217 724.9167 772.0500 1356671 1438039_at 12 17.0 cM chr12:52899719-52903413 12 C1 chr12:52844708-52930523 12 C1 RSQ Mm.249391 NM_144788 1 1 207304 Hectd1 HECT domain containing 1 (Hectd1), mRNA. ligase activity;; modification-dependent protein catabolic process;; neural tube closure catalytic activity ligase activity anatomical structure formation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; catabolic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process 35.7374 32.6337 29.8493 39.8351 33.3991 38.4030 163.2478 147.7732 174.5514 211.3018 129.7926 208.5287 88.3581 116.4891 84.9178 110.4941 103.5401 95.7212 1356722 1438121_at 11 B1.3 chr11:51555742-51556242 11 B1.3 UG5 Mm.33878 77371 RP23-79E13.2 Sec24a Sec24 related gene family, member A (S. cerevisiae), mRNA (cDNA clone IMAGE:40097170) COPII vesicle coat;; cytoplasm;; endoplasmic reticulum;; ER to Golgi vesicle-mediated transport;; Golgi apparatus;; intracellular protein transport;; membrane;; protein binding;; protein transport;; transport;; vesicle-mediated transport;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; protein complex;; vesicle binding ion binding;; protein binding cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; transport;; vesicle-mediated transport 43.9484 63.4938 55.7704 39.0858 64.7148 92.5332 46.7749 54.7022 43.9875 49.5882 47.1215 49.9422 16.3634 25.9153 28.5040 28.9214 32.5343 33.9773 1356731 1438130_at 11 B5 chr11:83312602-83313120 11 C UG5 Mm.181050 70439 RP23-249K18.5 Taf15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, mRNA (cDNA clone MGC:169215 IMAGE:8860610) 140.3890 153.9472 241.9809 86.0745 107.5890 117.9382 1462.5408 1454.6406 1701.3080 1762.8147 1494.3118 1793.7734 602.4358 785.0145 649.9297 660.0924 683.9703 631.4610 1371369 1438157_s_at 12 chr12:56590865-56590958 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 12.0680 10.2340 12.4131 8.6724 11.5941 12.4131 217.4673 220.9245 208.7671 257.2898 215.0177 262.8741 30.2697 54.2200 104.1772 84.1194 197.1745 67.7514 1356746 1438186_at chr3:141971528-141972059 3 H1 IPA ESTs 197.8609 219.2535 360.1041 178.5222 203.6051 246.2110 510.2973 504.4462 429.2583 424.0141 496.2075 422.9852 153.5402 168.4269 187.4452 153.8367 260.8984 266.0473 1356796 1438268_at 2 chr2:37230581-37232466 2 B chr2:37225588-37278423 2 B RSQ Mm.288785 NM_001100591 1 1 319817 RP23-321B3.1 Rc3h2 ring finger and CCCH-type zinc finger domains 2 (Rc3h2), mRNA. cytoplasm;; DNA binding;; membrane;; metal ion binding;; nucleic acid binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding ion binding;; nucleic acid binding;; protein binding 224.2664 262.9932 235.4833 123.1681 129.9345 192.1019 100.4560 103.6976 112.0441 100.2652 100.7457 100.1906 34.8471 20.4210 29.6377 47.6367 36.7214 56.6343 1356817 1438301_at 15 chr15:64021278-64021774 15 D1 UGA Mm.448964 Transcribed locus 81.2999 103.9303 102.3412 50.5371 54.5445 67.8636 266.9063 280.7991 379.9297 332.4683 290.5410 360.5058 133.1772 193.6487 158.6500 136.5355 204.6898 170.5408 1356946 1438519_at 16 chr16:20099161-20099591 16 A3 chr16:20097559-20099755 16 A3 RSQ XM_001476089 2 2 100046372 LOC100046372 PREDICTED: hypothetical protein LOC100046372 (LOC100046372), mRNA. 21.2564 20.3720 22.8678 26.3831 20.1254 20.8399 54.4976 58.0697 91.2653 54.7078 61.0425 50.0110 22.4752 26.6681 26.3432 25.0141 30.9379 29.8878 1356987 1438590_at 15 F1 chr15:97577164-97577499 15 F1 UGA Mm.24028 223864 Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), mRNA Phospholipase C-epsilon pathway Leukocyte transendothelial migration;; Long-term potentiation CLASS Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670] Cellular Processes; Nervous System; Long-term potentiation [PATH:mmu04720] cAMP binding;; cAMP-dependent protein kinase complex;; cAMP-dependent protein kinase regulator activity;; cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; membrane;; nucleotide binding;; regulation of protein amino acid phosphorylation;; regulation of small GTPase mediated signal transduction;; small GTPase mediated signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; nucleoside binding;; nucleoside-triphosphatase regulator activity;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 408.4207 470.9707 422.7119 345.1102 310.3843 367.7817 488.2773 510.3588 500.5888 478.8030 463.9491 491.4576 162.3036 218.4950 235.4287 192.9316 317.0435 272.6309 1357053 1438739_at 6 chr6:87797947-87798375 6 D1 UGA Mm.442804 Transcribed locus 46.2828 91.9212 65.8104 39.3562 52.6619 52.8498 355.6127 352.0069 384.0551 394.5174 349.1527 386.0964 172.9121 187.6682 216.5964 175.4524 208.5809 194.5486 1357081 1438781_at 3 G3 chr3:133142044-133142441 3 G3 UGA Mm.347816 214133 Tet2 Tet oncogene family member 2, mRNA (cDNA clone IMAGE:4977050) cell cycle;; iron ion binding;; kidney development;; metal ion binding;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; post-embryonic development binding;; catalytic activity ion binding;; oxidoreductase activity cellular process;; developmental process;; metabolic process;; multicellular organismal process anatomical structure development;; cell cycle;; multicellular organismal development;; oxidation reduction;; post-embryonic development 171.5156 144.7948 198.8308 123.5775 152.5676 145.3657 118.0139 139.8418 149.2430 133.0901 127.0740 116.4069 46.4102 73.6290 65.8165 51.4407 79.0361 70.6611 1357089 1438798_at 7 chr7:35070296-35070877 7 B1 chr7:35021732-35070628 7 B1 RSQ Mm.476734 NM_172741 1 1 233103 RP23-349I9.6 4931406P16Rik RIKEN cDNA 4931406P16 gene (4931406P16Rik), mRNA. 152.0032 181.1025 295.5370 92.8999 164.5964 155.1962 142.8638 149.6079 146.0964 137.0612 135.9632 138.6835 64.3738 63.9156 78.6038 63.7297 89.5286 87.4347 1357233 1439095_at 3 H4 chr3:157687705-157688252 3 H4 UGA Mm.223946 69207 Sfrs11 Splicing factor, arginine/serine-rich 11, mRNA (cDNA clone IMAGE:3154169) 57.3282 58.4893 50.2508 59.9648 61.0708 53.5075 136.1483 140.0742 266.1691 215.9390 139.9673 208.8900 92.0282 96.2282 108.5102 110.7052 143.7075 126.0056 1357241 1439106_at 4 chr4:55094004-55094435 4 B3 chr4:54960816-55096435 4 B3 RSQ Mm.102904 NM_172867 1 1 242466 RP23-281K3.2 Zfp462 zinc finger protein 462 (Zfp462), mRNA. negative regulation of DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 115.1031 89.9298 126.7564 136.9423 163.5035 141.5141 1755.6214 1879.8865 2351.9611 2631.1866 1887.1944 2621.2210 901.5860 852.0092 863.7312 777.1228 898.0928 815.5303 1357272 1439153_at 13 chr13:47342806-47343264 13 A5 UGA Mm.444782 Transcribed locus 339.2630 473.9347 352.7368 337.0690 263.3557 399.7697 327.4220 338.8890 567.2075 499.6368 320.0704 505.6848 238.2421 228.9852 275.1910 240.3910 285.0907 246.1738 1357279 1439161_at 19 A chr19:3483536-3484088 19 A UGA Mm.284686 52036 Saps3 SAPS domain family, member 3 (Saps3), mRNA cytoplasm;; nucleus;; protein phosphatase binding;; regulation of phosphoprotein phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cellular metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 64.1601 95.2217 100.5188 107.8495 92.2977 114.9438 3573.6306 3884.1631 3296.2708 3507.5675 3800.3058 3515.1346 845.2340 1082.5445 1281.3665 805.9278 988.0900 951.3946 1357281 1439163_at 9 A5.3|9 23.0 cM chr9:48462424-48462942 9 A5.3 UG5 Mm.457803 235320 Zbtb16 PLZF gene Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer anterior/posterior pattern formation;; DNA binding;; embryonic hindlimb morphogenesis;; embryonic limb morphogenesis;; embryonic pattern specification;; forelimb morphogenesis;; leg morphogenesis;; male germ-line stem cell division;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of transcription, DNA-dependent;; nucleus;; nucleus;; positive regulation of apoptosis;; protein binding;; protein binding;; regulation of transcription;; skeletal system development;; specific transcriptional repressor activity;; transcriptional repressor complex;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription repressor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; sexual reproduction 108.0997 131.2076 139.1095 85.0225 139.2075 120.6404 93.8105 84.3978 72.2247 79.7091 86.6970 73.1629 37.0535 36.0349 37.2588 34.5174 36.3144 50.8549 1357282 1439165_at 9 chr9:59325563-59326112 9 B UG5 Mm.446631 Transcribed locus 206.4627 235.2070 222.2245 186.3967 203.8590 208.7733 294.8061 284.7694 254.4991 276.2337 265.5554 263.5754 131.6521 104.2132 138.9178 120.6256 125.0834 115.7700 1357416 1439349_at 10 C1 chr10:79534037-79534504 10 C1 UGA Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 794.7965 1095.5431 1041.4124 484.6341 609.5017 550.9813 1134.4904 1102.3936 1726.9546 1713.5049 1101.0939 1746.5719 698.8299 946.4558 899.3651 1070.4813 1146.4497 1001.3727 1357444 1439477_at 11 chr11:51807342-51807651 11 B1.3 UGA Mm.440651 Transcribed locus 64.6811 91.5602 77.0269 86.7538 80.7037 68.5006 147.2066 148.2026 213.3186 210.7704 188.8862 216.1125 84.2190 81.7391 101.4926 78.7714 115.6253 96.0310 1357539 1439586_at 16 chr16:43565603-43566016 16 B4 UGA Mm.402642 Transcribed locus 187.9499 182.8059 162.4080 174.9788 99.8197 182.1767 301.9894 292.7219 287.8793 290.2378 268.1770 297.8017 133.4478 152.0964 138.6017 160.7075 188.2089 161.4817 1357600 1439652_at chr11:117524613-117525118 11 E2 IPA Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920011F17 product:unclassifiable, full insert sequence. 130.5410 129.7119 125.4053 151.9690 168.5146 117.7320 70.9977 72.5357 110.7813 85.4080 67.0821 84.8063 31.3987 33.7911 40.7677 39.8330 43.9981 44.6738 1357845 1439922_at 18 D3 chr18:57546777-57547286 18 D3 UG5 Mm.29889 73137 Prrc1 Proline-rich coiled-coil 1, mRNA (cDNA clone MGC:12103 IMAGE:3709357) Golgi apparatus;; identical protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding 90.8402 97.1373 61.6972 85.0225 78.6596 92.7921 113.5691 125.0568 138.5654 117.8266 139.0409 118.2776 58.5171 64.6572 58.5322 58.2837 69.3683 75.6772 1357924 1440013_at 2 chr2:102167076-102167568 2 E2 UGA Mm.450285 Transcribed locus 20.6117 31.7894 22.5429 23.5381 26.0521 21.5602 29.1586 28.9029 63.2457 54.4033 28.0957 63.3116 21.4183 21.5015 23.5698 20.3494 25.7466 30.6803 1357927 1440016_at chr3:116216915-116217450 3 G1 IPA ESTs 24.3947 18.0371 29.8493 30.0085 23.5057 28.7413 68.3447 62.2854 60.8887 39.5900 61.3614 54.8053 21.6634 21.8509 32.6299 25.6397 26.0670 24.4425 1358021 1440111_at chr2:52800127-52800424 2 C1.1 IPA ESTs 7.6092 8.2444 8.4881 9.2120 8.1885 8.3856 14.3817 16.9979 27.4909 29.1170 19.1379 18.4141 9.1428 8.3395 7.8130 12.1247 7.4821 9.5574 1371520 1440173_x_at 1 H2.2|1 86.6 cM UGA Mm.3337 20344 Selp Selectin, platelet (Selp), mRNA Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 44.9021 64.6098 41.5053 37.0819 44.0246 65.1925 402.5401 470.9924 775.5994 764.1519 448.4297 819.7624 56.0065 72.1527 166.4367 65.0852 78.3354 77.9224 1358216 1440347_at 8 chr8:79889434-79889899 8 C1 UGA Mm.438679 Transcribed locus 26.9830 32.4252 30.1983 24.3029 24.8337 25.2929 116.9287 112.6836 135.1414 138.6205 119.9223 149.7337 23.0892 30.6690 32.5484 31.0515 38.0452 42.1382 1358233 1440365_at chr16:37873054-37873603 16 B3 IPA ESTs 33.2900 49.1925 29.2599 33.1407 30.9532 33.5604 34.7377 39.9195 67.4997 55.0017 24.8014 47.4149 21.9513 31.3537 24.2717 24.7577 31.6263 22.7714 1358415 1440553_at 4 D2.3 chr4:131399933-131400415 4 D2.3 UG5 Mm.192706 26922 Mecr Mitochondrial trans-2-enoyl-CoA reductase, mRNA (cDNA clone MGC:6611 IMAGE:3488760) Fatty acid elongation in mitochondria;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Fatty acid elongation in mitochondria [PATH:mmu00062] binding;; catalytic activity;; cytosol;; fatty acid biosynthetic process;; ligand-dependent nuclear receptor binding;; lipid biosynthetic process;; metabolic process;; mitochondrion;; nucleus;; oxidation reduction;; oxidoreductase activity;; trans-2-enoyl-CoA reductase (NADPH) activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity;; protein binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; oxidation reduction;; primary metabolic process 34.5375 39.5236 32.1234 48.6364 61.3015 42.9658 189.2891 195.8563 316.2382 282.8826 175.6980 290.0800 67.8665 91.5648 100.6155 82.3463 110.6589 99.3211 1358427 1440565_at chr16:43560712-43561239 16 B4 IPA Mus musculus adult male liver tumor cDNA, RIKEN full-length enriched library, clone:C730020C12 product:unknown EST, full insert sequence. 62.2893 80.1728 64.8413 91.2603 89.2096 66.0904 198.8208 222.1484 391.5528 381.2644 252.8548 399.2307 140.9491 241.4751 125.7445 126.7693 135.9037 154.7423 1358496 1440635_at 8 B3.3 chr8:64162534-64162869 8 B3.1 UG5 Mm.29933 72333 Palld Palladin, cytoskeletal associated protein, mRNA (cDNA clone IMAGE:4947562) actin binding;; actin filament;; cytoplasm;; cytoskeleton;; nucleus cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding 69.9459 56.1909 93.1692 88.5572 98.4091 62.9310 403.3556 533.3844 139.3842 134.4529 408.7996 127.6467 62.4265 59.6349 66.7521 62.5685 100.1319 105.9936 1358631 1440776_at 5 C3.1 chr5:67139353-67139604 5 C3.1 UGA Mm.374778 77569 Limch1 LIM and calponin homology domains 1 (Limch1), mRNA actin binding;; actomyosin structure organization;; metal ion binding;; zinc ion binding binding ion binding;; protein binding cellular component organization;; cellular process actin filament-based process;; organelle organization 72.5302 140.8143 138.6523 60.4662 119.0027 62.8966 156.4297 164.7850 257.8080 263.8041 147.7269 273.6190 61.1835 86.1201 84.9668 89.4151 77.5550 66.0139 1358665 1440847_at 15 chr15:58884333-58884882 15 D1 UGA Mm.394414 Transcribed locus 67.0393 85.6099 69.1578 81.5577 94.1552 80.1436 402.8916 413.1497 452.5408 423.2220 410.4421 456.1665 179.4001 214.7810 188.7075 221.3186 225.9248 161.7630 1358736 1440926_at 5 chr5:148446897-148447256 5 G3 UGA Mm.458302 Transcribed locus 52.5793 68.9754 98.8269 61.6745 58.7432 63.2842 106.0855 122.9753 117.2209 137.9853 121.4382 112.7852 56.3572 58.0596 66.1610 51.3043 63.7846 81.9686 1358826 1441026_at 14 chr14:57248034-57260154 14 C3 chr14:57194455-57278635 14 C3 RSQ Mm.379357 NM_001145978 1 1 328417 Parp4 poly (ADP-ribose) polymerase family, member 4 (Parp4), mRNA. Base excision repair CLASS Genetic Information Processing; Replication and Repair; Base excision repair [PATH:mmu03410] enzyme binding;; nucleus;; protein binding;; spindle;; telomere maintenance via telomerase cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological quality 64.0650 59.1759 62.8992 59.6237 75.1871 54.1425 56.7222 52.3348 108.4439 93.7802 57.4383 97.4960 32.6699 34.8461 27.8261 43.7040 47.2600 49.5404 1358842 1441042_at 18 B3|18 19.0 cM chr18:39006345-39006814 18 B3 UGA Mm.241282 14164 Fgf1 Fibroblast growth factor 1, mRNA (cDNA clone MGC:46904 IMAGE:5137246) BTG family proteins and cell cycle regulation MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Melanoma [PATH:mmu05218];; Pathways in cancer;; Regulation of actin cytoskeleton angiogenesis;; cell differentiation;; cell proliferation;; extracellular space;; growth factor activity;; heparin binding;; induction of an organ;; lung development;; multicellular organismal development;; positive regulation of epithelial cell proliferation;; positive regulation of protein amino acid phosphorylation;; protein binding;; proteinaceous extracellular matrix extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space binding carbohydrate binding;; pattern binding;; protein binding anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 210.9490 201.5687 155.7406 215.1959 224.0505 184.0104 338.6572 314.7363 353.4556 318.8421 341.7281 345.8223 167.2319 158.5474 166.0408 155.4993 176.8335 195.6824 1358975 1441185_at 11 chr11:88291497-88292043 11 C UGA Mm.443787 Transcribed locus 140.9122 129.9372 140.4589 160.0506 101.8413 172.6618 166.6573 176.0408 396.8003 359.5980 162.3692 355.7399 170.8752 110.9951 128.5818 200.7335 120.2462 193.5358 1359017 1441228_at 6 G1 chr6:134936253-134936706 6 G1 UG5 Mm.296104 381823 Apold1 Apolipoprotein L domain containing 1 (Apold1), mRNA 140.4863 132.2007 156.4601 164.0605 167.3950 97.4118 237.6343 201.2525 291.3669 266.1877 205.6262 253.6830 102.5081 103.5356 127.6522 99.8509 107.9631 104.6264 1359019 1441230_at chr3:27511416-27511951 3 A3 IPA ESTs 70.1884 107.7686 64.3520 102.6899 92.6490 84.5784 353.1258 357.8242 373.9311 364.5717 309.5399 351.0311 185.9330 171.8159 152.2308 176.4852 220.3137 238.6867 1359105 1441331_at 10 chr10:13699848-13700364 10 A2 UGA Mm.395880 Transcribed locus 29.4412 40.8409 35.6371 27.9002 28.3607 54.5232 61.5857 66.7412 82.9808 71.6041 60.4484 81.4700 20.5868 18.3784 21.2249 17.0989 20.1133 23.2670 1359158 1441388_at 18 E2|18 44.0 cM chr18:70788193-70788698 18 E2 UGA Mm.322 17191 Mbd2 Methyl-CpG binding domain protein 2 (Mbd2), mRNA cellular protein complex assembly;; chromatin;; chromatin binding;; cytoplasm;; DNA binding;; heterochromatin;; histone deacetylase complex;; maternal behavior;; methyl-CpG binding;; mRNA binding;; negative regulation of transcription from RNA polymerase II promoter;; nucleolus;; nucleus;; positive regulation of Wnt receptor signaling pathway;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; siRNA binding;; transcription cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding chromatin binding;; nucleic acid binding;; nucleotide binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus behavior;; biosynthetic process;; cell communication;; cell proliferation;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organism reproduction;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive behavior;; reproductive process;; reproductive process in a multicellular organism 36.3520 45.6915 52.0680 33.9292 30.4712 41.4115 98.7170 102.9127 72.4076 91.0624 90.3403 73.1543 39.7298 27.8208 32.8831 34.1662 30.8210 27.0988 1359231 1441467_at 3 chr3:138436873-138437414 3 H1 UG5 Mm.417274 Transcribed locus 27.5625 37.6135 22.6245 33.1903 30.4599 31.5294 295.8671 252.2945 241.4638 243.5553 262.4004 254.9852 46.4991 91.8810 74.2362 63.4255 79.3802 85.1542 1359294 1441531_at 2 F3|2 77.0 cM chr2:135486868-135487311 2 F3 UGA Mm.38009 18798 RP23-7A19.1 Plcb4 Phospholipase C beta 4 [Mus musculus], mRNA sequence Alzheimer's disease;; Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Huntington's disease CLASS Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism [PATH:mmu00562] Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Environmental Information Processing; Signal Tr;; Inositol phosphate metabolism;; Long-term depression;; Long-term potentiation;; Melanogenesis;; Metabolic pathways;; Phosphatidylinositol signaling system;; Vascular smooth muscle contraction;; Wnt signaling pathway dendrite;; microsome;; nucleus;; postsynaptic density;; protein binding;; signal transducer activity;; signal transduction;; smooth endoplasmic reticulum cell;; cell part;; organelle;; organelle part;; synapse;; synapse part cell fraction;; cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; postsynaptic density;; synapse part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 50.8920 60.6640 60.2180 38.3106 60.5877 51.8224 173.8961 194.4956 189.7186 161.7630 192.6397 199.1457 54.8421 71.6546 79.9890 72.5843 105.3909 92.1812 1359354 1441592_at 10 chr10:66595201-66595683 10 B5.1 UGA Mm.440483 Transcribed locus 692.1311 848.8775 733.2474 571.2050 718.4224 919.5458 266.1519 287.5964 217.6730 212.3186 250.5536 189.2485 96.2681 86.7958 112.8333 121.7676 132.4307 119.1528 1359356 1441594_at chr5:104199317-104199794 5 E5 IPA Mus musculus 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130072L14 product:unclassifiable, full insert sequence. 4990.9610 8572.9190 4602.9604 3444.0911 4313.1779 4895.8741 94.2228 95.2816 111.9263 105.7460 97.7207 109.6878 49.1933 37.9325 42.1065 40.6583 62.2397 79.2415 1359404 1441643_at 18 D2|18 chr18:57081974-57082425 18 D3 UGA Mm.312623 320253 March3 Membrane-associated ring finger (C3HC4) 3, mRNA (cDNA clone MGC:130168 IMAGE:40052074) cytoplasmic vesicle;; endocytosis;; endosome;; integral to membrane;; ligase activity;; membrane;; metal ion binding;; modification-dependent protein catabolic process;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; vesicle binding;; catalytic activity ion binding;; ligase activity cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; membrane organization;; primary metabolic process;; transport;; vesicle-mediated transport 88.0507 101.6071 114.9199 74.1515 101.0060 139.8389 108.5201 97.3989 121.2243 103.9130 100.2368 86.9045 34.3091 42.7821 44.3701 32.7660 60.9468 52.6401 1359413 1441653_at 7 F3 UG5 Mm.428042 100043597 Srcap PREDICTED: Mus musculus similar to Snf2-related CBP activator protein (LOC100043597), mRNA 38.7670 35.5947 37.0514 40.5941 35.7277 26.5641 295.7682 330.0745 556.0856 515.3655 288.4852 490.3606 40.4972 46.7996 52.1493 43.1577 49.2335 33.4377 1359551 1441799_at chr17:28557117-28557366 17 A3.3 IPA ESTs 83.3374 101.0482 115.7410 49.3910 86.0519 71.8314 244.3128 237.3712 244.5804 205.8857 216.6854 190.7352 83.8888 88.7387 78.5967 111.3767 148.9563 91.4507 1359571 1441823_at 14 A3 chr14:26357806-26357946 14 A3 UGA Mm.227484 328365 Zmiz1 Zinc finger, MIZ-type containing 1, mRNA (cDNA clone MGC:86031 IMAGE:6856060) artery morphogenesis;; cell aging;; cytoplasm;; developmental growth;; heart morphogenesis;; in utero embryonic development;; metal ion binding;; nucleus;; positive regulation of fibroblast proliferation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; vasculogenesis;; vitellogenesis;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; protein binding biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process aging;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell aging;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytoplasm organization;; developmental growth;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 47.5057 76.4959 71.9274 32.7984 55.9516 35.3354 157.2023 157.9271 65.0842 60.3673 156.1753 62.0749 21.0842 25.0583 23.2114 20.3063 20.1412 27.7300 1359586 1441858_at IPA Unknown 69.0003 69.4473 100.5294 72.4693 104.0063 86.2019 195.5848 209.3417 321.5302 286.6683 213.7386 313.9896 89.1899 115.1755 124.6443 108.3646 140.6030 126.4641 1359741 1442102_at chr15:81730419-81730848 15 E1 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 130.5797 171.1897 145.7716 126.2789 150.7830 166.4501 121.9903 140.9872 196.3524 209.9480 121.9719 192.2458 78.2709 80.3196 70.8618 50.9950 91.0495 93.9846 1359835 1442198_at chr1:140431997-140432313 1 E4 IPA ESTs 69.8901 76.6382 93.0362 57.8956 69.4495 66.6576 156.7052 185.3186 216.7157 181.0322 163.2232 152.3227 78.5700 83.5973 84.6532 76.6382 84.2912 92.0618 1359883 1442248_at 15 chr15:27843701-27844181 15 B1 UGA Mm.453300 Transcribed locus 125.8871 106.2417 83.5418 122.7224 107.5698 106.4896 202.7384 170.3354 278.1816 346.1456 175.7180 405.7709 99.0323 122.0745 107.6189 104.2723 92.1195 103.1021 1359891 1442256_at 14 B|14 11.0 cM UGA Mm.2314 18753 Prkcd Protein kinase C delta HIV-I Nef: negative effector of Fas and TNF;; Keratinocyte Differentiation Chemokine signaling pathway;; Fc epsilon RI signaling pathway;; GnRH signaling pathway;; Neurotrophin signaling pathway;; Tight junction;; Type II diabetes mellitus CLASS Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] Cellular Processes; Immune System; Fc epsilon RI signaling pathway [PATH:mmu04664] C;; Vascular smooth muscle contraction ATP binding;; B cell proliferation;; cytoplasm;; diacylglycerol binding;; immunoglobulin mediated immune response;; insulin receptor substrate binding;; interleukin-10 production;; interleukin-12 production;; intracellular signaling cascade;; kinase activity;; membrane;; metal ion binding;; negative regulation of insulin receptor signaling pathway;; negative regulation of peptidyl-tyrosine phosphorylation;; nucleotide binding;; protein amino acid phosphorylation;; protein kinase activity;; protein kinase C activity;; protein serine/threonine kinase activity;; transferase activity;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; lipid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell communication;; cell proliferation;; cellular metabolic process;; cellular response to stimulus;; cytokine production;; immune effector process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; negative regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 52.2122 102.2695 76.8889 45.0442 82.3618 58.3548 42.4037 42.3992 60.4668 45.0442 45.5486 41.7707 25.8122 24.0430 19.7156 23.9731 22.3705 29.7244 1359911 1442277_at 19 A|19 3.0 cM chr19:3865272-3865840 19 A UGA Mm.225505 12660 Chka Choline kinase alpha, mRNA (cDNA clone IMAGE:3582342) Glycerophospholipid metabolism;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] ATP binding;; choline kinase activity;; cholinesterase activity;; cytoplasm;; ethanolamine kinase activity;; kinase activity;; nucleotide binding;; phosphatidylcholine biosynthetic process;; protein homodimerization activity;; transferase activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; organophosphate metabolic process;; primary metabolic process 56.1113 75.2179 61.8412 64.3822 64.7708 55.2873 635.3268 556.4423 321.3202 260.5442 554.1874 255.1722 80.0638 81.4781 69.1425 67.0231 172.8667 154.7860 1360020 1442395_at 1 chr1:34085393-34085906 1 B UGA Mm.436779 Transcribed locus 38.0172 44.6169 28.0243 42.4800 52.2537 30.1563 1114.5956 1047.2592 1144.4827 1230.9785 1032.7740 1257.3657 324.0741 254.3387 247.1169 291.8388 239.1054 373.2075 1360313 1442710_at chr3:142052865-142053312 3 H1 IPA ESTs 23.1145 31.6702 22.9479 28.8123 24.5837 32.1836 108.3114 94.5578 54.6833 62.9802 86.2277 70.8922 25.3861 22.8807 21.2392 17.9689 22.0659 24.8968 1360328 1442725_at 11 UG5 Mm.419280 Transcribed locus 30.8083 48.0268 41.9479 24.8527 31.6265 32.2719 163.2630 158.7630 136.6911 118.8242 159.4576 139.6533 34.6420 28.8970 46.9103 36.7855 44.6911 34.0372 1360350 1442750_at 13 A1 chr13:14064362-14064580 13 A1 UG5 Mm.21686 97884 B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2, mRNA (cDNA clone MGC:103263 IMAGE:30735904) acetylgalactosaminyltransferase activity;; galactosyltransferase activity;; Golgi apparatus;; integral to membrane;; membrane;; protein amino acid glycosylation;; transferase activity;; transferase activity, transferring glycosyl groups;; UDP-N-acetylgalactosamine metabolic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 21.4183 22.0212 20.8847 26.3284 23.7281 17.9895 50.7236 53.3655 38.9279 43.6176 54.1636 37.2293 17.1394 20.8037 20.8019 18.2843 21.4093 21.6638 1360461 1442880_at 16 chr16:34559830-34560160 16 B3 UGA Mm.24752 Transcribed locus 20.5937 22.1196 20.9172 24.6360 18.8707 19.6075 215.5388 208.2831 151.4427 174.0500 213.1139 190.4266 65.3367 61.8438 43.4317 67.4483 66.3242 65.9911 1360495 1442916_at 8 chr8:70533034-70533494 8 B3.3 UGA Mm.403977 Transcribed locus 28.4946 33.8186 34.8463 30.3569 33.0564 27.6851 110.8251 106.4425 88.2901 102.2695 105.9811 64.8960 25.1054 37.9253 30.4765 18.8508 23.0231 24.8187 1360542 1442967_at 8 chr8:80016360-80016899 8 C1 UGA Mm.394850 Transcribed locus 87.0538 101.9016 86.3037 109.7104 135.4503 95.5356 172.1387 207.6292 279.1356 188.7146 189.9008 225.3057 65.4049 56.6737 66.3821 47.5895 50.3558 77.0885 1360637 1443069_at 11 chr11:108041099-108041513 11 E1 UGA Mm.447682 Transcribed locus 29.5326 50.7203 28.4933 45.1224 40.6373 35.4435 140.4297 146.9383 364.9948 405.3497 125.8017 366.8801 118.7726 137.7341 120.9021 144.1744 167.6070 161.0341 1360668 1443100_at 14 chr14:18661754-18662090 14 A2 UGA Mm.406687 Transcribed locus 46.6734 40.9756 59.7991 34.1923 55.8047 41.3336 72.6079 96.6085 124.7546 127.0538 89.3265 135.7793 64.6796 61.8438 61.9189 55.1115 73.4327 74.0233 1360728 1443160_at 7 F2 chr7:117590515-117591052 7 F1 UGA Mm.102970 319934 Sbf2 SET binding factor 2, mRNA (cDNA clone IMAGE:4527932) phosphatase binding;; phosphatase regulator activity;; phosphoinositide binding;; protein homodimerization activity;; protein tetramerization;; vacuolar membrane cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; enzyme regulator activity lipid binding;; phosphatase regulator activity;; protein binding anatomical structure formation;; cellular component biogenesis;; cellular component organization cellular component assembly;; macromolecular complex subunit organization;; protein complex biogenesis 21.9055 29.5991 25.0553 19.4371 22.8072 23.7948 85.4342 95.8322 30.7800 35.1871 90.8806 39.0084 14.0207 18.2806 13.0802 17.2148 22.3893 21.5777 1360780 1443212_at chr8:75853675-75854162 8 B3.3 IPA ESTs 291.0206 276.2902 280.7065 261.4107 338.1121 261.6444 379.3940 467.5063 652.0214 582.2813 384.8710 614.0051 99.3446 119.9860 182.1062 127.9102 182.0265 147.5609 1360856 1443289_at 13 chr13:110571699-110572038 13 D2.2 UGA Mm.438644 Transcribed locus 18.9475 19.3433 19.3770 21.2688 24.0734 18.7047 81.0221 90.9414 58.8973 59.3283 77.0503 65.6579 32.5111 27.7499 28.6288 32.7734 37.0729 24.2394 1360905 1443341_at chr6:86724341-86724697 6 D1 IPA ESTs 36.3096 45.7751 33.0002 29.9394 42.0750 34.3861 69.6108 58.2016 85.2639 94.8588 72.3165 93.1718 32.2810 36.3479 55.1627 35.1483 34.1171 26.4292 1360981 1443430_at 10 chr10:94753539-94754027 10 C2 IPA Mm.218009 Transcribed locus, strongly similar to NP_034080.1 CASP2 and RIPK1 domain containing adaptor with death domain [Mus musculus] 73.8240 56.7120 58.9727 68.9656 62.3812 75.9346 326.0674 351.6342 350.3305 390.8186 316.6741 426.0877 120.8400 146.7881 144.0995 130.7251 182.4987 137.0706 1361015 1443471_at 16 B4|16 28.9 cM chr16:43613020-43613517 16 B4 UGA Mm.440824 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 53.6095 52.9187 72.8547 52.0455 70.1536 48.0667 186.4252 175.2630 157.6697 157.7437 147.1039 159.7878 56.3572 51.3663 84.2719 58.2837 71.0292 59.2253 1361052 1443511_at 9 chr9:68763941-68764383 9 C UGA Mm.445349 Transcribed locus 38.8706 53.5674 44.9518 40.6607 37.0894 41.5015 125.6585 163.4560 84.4351 113.5318 133.2735 115.0222 28.5328 34.8730 41.0085 48.2582 41.7653 33.6439 1371794 1443721_x_at 10 C1 chr10:79529116-79529323 10 C1 UG5 Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 47.3182 72.3441 52.6479 40.1667 39.7736 43.5499 275.9301 274.3183 225.8753 254.2836 284.0659 254.5912 103.0577 128.4636 118.2085 139.5280 189.8043 116.3899 1361430 1443983_at 19 UGA Mm.440351 Transcribed locus 38.7490 36.6002 28.1074 24.5418 27.1123 23.0378 19.4828 22.3272 35.1562 28.1248 18.4700 26.2691 9.9962 13.9907 16.2625 14.4558 14.1765 20.5628 1361482 1444037_at 18 chr18:66160219-66160695 18 E1 UG5 Mm.449042 Transcribed locus, strongly similar to NP_081676.1 lectin, mannose-binding, 1 [Mus musculus] 59.8691 67.2052 52.4493 40.5068 39.2143 30.9462 40.3275 31.3250 31.0269 33.4682 44.4047 34.2422 12.8354 16.1381 19.1216 18.5444 23.6359 19.3370 1361501 1444057_at 1 chr1:130147437-130147962 1 E4 UGA Mm.446146 Transcribed locus 54.4544 58.8451 65.4843 73.6432 71.2209 57.9951 6060.1090 6164.7448 6737.7447 6963.3823 6182.4311 6968.6388 1966.7949 3930.4750 2831.6241 2017.0201 3019.9332 3655.0646 1361527 1444083_at 2 44.0 cM chr2:76783445-76783867 2 C3 RSQ Mm.373672 NM_028004 2 1 22138 RP23-82M15.1 Ttn titin (Ttn), transcript variant N2-B, mRNA. A band;; adult heart development;; ATP binding;; calcium ion binding;; calmodulin binding;; cardiac myofibril assembly;; cytoplasm;; forward locomotion;; heart morphogenesis;; I band;; in utero embryonic development;; kinase activity;; M band;; magnesium ion binding;; metal ion binding;; muscle contraction;; muscle myosin complex;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; sarcomere;; sarcomere organization;; sarcomere organization;; somitogenesis;; striated muscle cell development;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity;; Z disc cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; locomotion;; metabolic process;; multicellular organismal process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; directional locomotion;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; pattern specification process;; primary metabolic process;; system process 474.9566 384.4297 429.1838 390.7353 301.5964 426.4846 462.2403 498.3186 611.1099 576.7075 494.1955 648.2397 250.5562 265.7846 275.1798 281.5707 285.4120 236.8382 1361549 1444107_at 12 chr12:85490277-85490794 12 D1 UGA Mm.394928 Transcribed locus 165.6725 146.8564 114.1654 131.1398 116.0802 126.5627 143.4362 185.5736 157.3806 159.4961 153.3083 159.0004 66.3007 93.3418 76.0185 76.7455 101.0826 88.7940 1361862 1444430_at chr9:99407238-99407662 9 E3.3 IPA Mus musculus 13 days embryo lung cDNA, RIKEN full-length enriched library, clone:D430004H12 product:hypothetical protein, full insert sequence. 76.9129 94.7102 87.2624 73.5562 87.7900 86.1282 95.7676 98.5535 138.1638 128.4840 91.1180 132.8384 49.6214 48.3193 59.7940 60.3531 56.6508 44.6017 1361879 1444447_at chr1:140464411-140464853 1 E4 IPA Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4932441M09 product:unknown EST, full insert sequence. 106.1898 108.3760 95.1380 129.6047 98.1022 119.0384 234.3698 213.4930 189.9336 207.4297 173.1746 200.1280 70.2563 77.0484 70.3311 65.1724 78.1472 79.7813 1361920 1444489_at 2 C2 UGA Mm.30928 78830 RP23-299A2.2 Slc25a12 Solute carrier family 25 (mitochondrial carrier, Aralar), member 12, mRNA (cDNA clone MGC:67718 IMAGE:6311836) binding;; calcium ion binding;; integral to membrane;; malate-aspartate shuttle;; membrane;; mitochondrial inner membrane;; mitochondrial inner membrane;; mitochondrion;; mitochondrion;; transport;; transporter activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; transporter activity ion binding cellular process;; establishment of localization;; localization;; metabolic process cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; oxidation reduction;; transport 39.2157 45.0231 36.3204 44.5490 40.4108 37.3496 38.3635 39.2204 58.0893 61.0574 33.6216 70.6657 31.0597 26.9572 28.2050 22.7127 24.0222 27.8219 1362015 1444587_at 13 chr13:110580551-110580864 13 D2.2 UGA Mm.437139 Transcribed locus 50.4768 62.4703 102.7394 70.4829 66.1623 97.6064 4365.6597 4415.7854 4566.3803 4608.2352 4492.6782 4578.5964 1362.5062 2017.7015 2183.0759 1388.6971 2421.8722 2453.5706 1362062 1444638_at 2 44.0 cM chr2:76803223-76807243 2 C3 RSQ Mm.373672 NM_011652 2 1 22138 RP23-82M15.1 Ttn titin (Ttn), transcript variant N2-A, mRNA. A band;; adult heart development;; ATP binding;; calcium ion binding;; calmodulin binding;; cardiac myofibril assembly;; cytoplasm;; forward locomotion;; heart morphogenesis;; I band;; in utero embryonic development;; kinase activity;; M band;; magnesium ion binding;; metal ion binding;; muscle contraction;; muscle myosin complex;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; sarcomere;; sarcomere organization;; sarcomere organization;; somitogenesis;; striated muscle cell development;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity;; Z disc cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; locomotion;; metabolic process;; multicellular organismal process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; directional locomotion;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; pattern specification process;; primary metabolic process;; system process 117.0976 120.4124 149.0219 110.8678 80.2873 117.6571 168.6519 169.7282 209.2845 162.7633 171.3925 175.4297 73.4184 77.6593 83.5096 77.8880 109.0339 104.4686 1362074 1444651_at 11 chr11:65564609-65564943 11 B3 UGA Mm.445744 Transcribed locus 50.8936 61.9053 56.1062 71.3171 58.4489 61.6652 86.7458 93.7287 115.2145 114.1421 89.3794 109.8215 37.3903 43.4746 39.5974 35.8851 48.9263 41.5563 1362172 1444749_at 16 chr16:31305712-31306199 16 B2 UGA Mm.436754 Transcribed locus 80.8363 69.4924 80.0849 94.0562 99.3692 81.3699 958.4100 945.1917 1056.8681 1076.9852 902.3013 991.0408 123.7372 125.1752 190.9852 136.0379 172.2246 167.8797 1362387 1444973_at chr14:24571790-24572277 14 A3 IPA ESTs 101.9873 106.0217 78.5850 103.4019 109.3224 101.7479 154.1064 189.3494 220.0138 160.2974 152.5233 191.6328 111.6598 80.3699 80.1381 89.9494 110.5747 115.1445 1362396 1444982_at chr12:76442505-76443010 12 C3 IPA C230007H23Rik RIKEN cDNA C230007H23 gene 44.4352 50.0524 37.3470 45.3961 47.8865 39.9166 248.1519 219.4084 542.2619 507.4418 234.4187 462.3202 103.7687 115.7316 127.6573 104.4197 93.6171 96.9214 1362558 1445148_at chr1:55487728-55488266 1 C1.2 IPA Mus musculus 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230091K16 product:unknown EST, full insert sequence. 72.0165 89.3484 79.2312 82.4777 125.6837 54.5928 328.6624 337.6353 556.8844 510.7315 313.1603 540.3797 58.1042 75.4649 128.1454 69.2576 82.7807 94.5636 1362797 1445395_at 11 chr11:108132382-108132923 11 E1 UGA Mm.443896 Transcribed locus 37.2838 36.1768 34.7662 45.7472 49.8620 44.2828 351.0118 343.7526 157.5952 129.5364 347.9196 127.2414 61.1687 60.7533 67.3254 78.4704 83.7358 76.9620 1362800 1445398_at 5 chr5:67306909-67307387 5 C3.1 UGA Mm.454791 Transcribed locus 30.2094 32.5636 29.4121 27.3514 27.2699 23.9333 360.0408 421.2584 364.6539 398.1917 402.3972 373.8282 156.9860 175.3773 191.5861 160.0409 168.0797 184.0005 1362845 1445443_at chr7:52694090-52694571 7 B4 IPA ESTs, Weakly similar to I58401 protein-tyrosine kinase (EC 2.7.1.112) JAK3 - mouse [M.musculus] 113.0824 104.6071 102.4358 92.0943 89.8272 88.3457 1148.0142 1246.0130 1152.8104 1269.0108 1230.3134 1241.8741 145.2623 151.5829 134.9756 114.9731 143.4127 168.1867 1362958 1445562_at chr9:48638602-48638777 9 A5.3 IPA ESTs 34.1817 34.8460 36.2131 25.8895 32.5871 37.8551 93.4520 109.2569 68.7509 77.3092 88.0225 71.9055 36.2197 34.3016 38.3882 38.5707 58.2108 39.0783 1363080 1445695_at 13 chr13:45701247-45701513 13 A5 UGA Mm.453409 Transcribed locus 68.5551 88.6749 74.4672 96.0924 74.1951 69.4283 321.4407 327.4148 340.8929 316.1018 322.8254 368.5697 58.7359 70.8420 97.8126 74.9895 76.0959 120.0523 1363152 1445774_at chr14:24589566-24590021 14 A3 IPA Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330037B11 product:unknown EST, full insert sequence. 39.2034 38.4510 43.8003 49.8877 40.6373 35.7670 47.8348 51.0117 101.1707 101.9682 53.2824 106.6829 40.9233 32.8096 48.3425 40.2215 31.0515 39.3015 1363186 1445809_at 10 chr10:23067802-23068323 10 A3 UGA Mm.444891 Transcribed locus 18.4443 20.2254 21.9466 25.1297 19.5348 26.9852 78.9087 61.2710 68.0409 79.0972 75.7856 68.9475 22.1397 35.5882 26.0666 28.5508 34.7242 40.9233 1363227 1445850_at 1 F chr1:136676358-136676868 1 E4 UGA Mm.188709 329251 Ppp1r12b Protein phosphatase 1, regulatory (inhibitor) subunit 12B, mRNA (cDNA clone MGC:175633 IMAGE:40131049) Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] cytoplasm cell;; cell part cell part;; intracellular;; intracellular part 147.4297 177.8365 115.6469 121.6921 195.1519 178.6500 221.0408 199.6425 200.9565 174.0864 195.1083 216.0408 73.5798 87.3461 91.4333 75.5634 88.6640 109.6386 1363268 1445892_at 1 C5 chr1:93338360-93338775 1 D IPA Mm.218141 Per2 Period homolog 2 (Drosophila) (Per2), mRNA 62.6535 100.6392 76.1213 53.0776 71.0884 69.4443 103.2695 124.3964 120.1052 115.1138 120.8903 129.2252 50.6661 68.7361 50.0121 48.6263 42.3994 57.1995 1363491 1446118_at chr17:30161295-30161855 17 A3.3 IPA ESTs 27.2588 28.7282 24.6552 27.0689 25.1552 35.7810 22.3955 23.8650 48.0810 41.6238 20.6031 44.5490 17.5490 20.6898 18.4870 22.6002 17.3948 19.7262 1363507 1446134_at chr15:66989390-66989885 15 D2 IPA ESTs 107.2635 150.0703 102.1511 101.3177 101.9804 133.0312 125.8149 125.1290 134.0971 122.2630 127.4106 116.4261 34.0230 22.3451 35.0172 25.7968 22.3451 38.6829 1363536 1446167_at chr6:38733170-38733515 6 B1 IPA Mus musculus 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930417E23 product:unknown EST, full insert sequence. 102.1163 91.3498 93.6335 116.8456 116.3106 101.5069 470.2001 485.9386 381.5703 303.1981 454.2227 314.4421 91.6713 117.2947 146.0780 90.1393 76.0707 99.0206 1363613 1446245_at chr2:52721981-52722503 2 C1.1 IPA Mus musculus 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030463N01 product:unknown EST, full insert sequence. 58.5927 92.4537 85.6026 56.5432 107.7555 51.4469 97.9039 83.4940 146.7349 145.4297 97.0095 148.3797 30.6667 41.7563 35.4552 22.3499 38.1765 32.4208 1363652 1446284_at 15 D1 chr15:58871422-58871951 15 D1 UGA Mm.215481 211401 Mtss1 Metastasis suppressor 1, mRNA (cDNA clone IMAGE:5343395) actin binding;; actin filament organization;; actin filament polymerization;; cytoplasm;; cytoskeletal adaptor activity;; cytoskeleton;; filopodium assembly;; muscle organ development;; nervous system development;; SH3 domain binding;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding molecular adaptor activity;; protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process actin filament-based process;; anatomical structure development;; cell communication;; cell projection organization;; cellular component assembly;; cellular macromolecular complex subunit organization;; macromolecular complex subunit organization;; multicellular organismal development;; organelle organization;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process 152.5679 149.5114 169.1118 159.7770 202.6519 149.6527 189.0522 194.9629 348.4954 321.4219 190.1916 319.5474 148.4307 122.0245 114.1632 124.3191 105.7300 138.5903 1363714 1446346_at 6 chr6:92875090-92875609 6 D1 UGA Mm.158235 Transcribed locus, moderately similar to NP_891550.1 ADAM metallopeptidase with thrombospondin type 1 motif, 9 preproprotein [Homo sapiens] 27.5810 19.8395 25.0558 26.8044 22.3185 26.3161 118.0553 145.7107 170.1519 176.0408 126.1461 197.3078 83.4458 67.6365 90.6181 76.9487 72.4503 57.8243 1363783 1446417_at chr13:34020506-34021041 13 A3.3 IPA ESTs 30.0002 31.7687 27.8236 33.3039 27.7376 39.1159 219.3186 216.2710 258.9297 198.1867 234.0584 208.9740 76.0590 64.5594 69.0432 55.7863 89.3368 71.0276 1363787 1446421_at 3 chr3:68407435-68407941 3 E1 UGA Mm.448005 Transcribed locus 46.6734 40.8665 41.4800 31.8958 46.0881 40.9603 522.8414 468.4297 382.1519 379.8186 519.3505 338.5408 94.2610 92.2798 88.5187 101.5126 89.1817 115.5708 1363841 1446475_at 14 chr14:120692309-120692809 14 E4 UG5 Mm.453644 Transcribed locus 50.9236 75.2505 59.7120 46.6197 65.4652 70.6477 66.3173 65.7148 135.2879 117.4626 77.2464 108.7614 35.0984 31.0789 44.2829 13.2299 21.4879 16.3409 1363875 1446509_at chr2:131342326-131342825 2 F1 IPA B130066H01Rik RIKEN cDNA B130066H01 gene 48.3701 66.1561 56.4146 54.8053 65.7806 54.5510 117.2567 117.8665 114.3109 128.7509 119.0060 127.2256 54.0989 73.0710 58.7465 45.4299 68.4685 91.3324 1363935 1446569_at chr13:115886164-115886710 13 D2.2 IPA Unknown 120.8396 125.5882 93.7842 135.2004 133.4870 141.9380 767.4668 821.5117 1076.8741 879.3519 818.7366 952.5834 189.5512 156.4297 251.6615 144.4612 149.5121 178.7410 1363963 1446598_at 11 UGA Mm.441616 Transcribed locus 127.4867 132.5917 145.6007 109.6710 100.5020 157.2862 135.0681 139.0443 205.4459 171.2456 145.4135 153.8627 73.4902 48.9827 90.9201 57.0676 57.9317 74.0400 1363986 1446621_at 4 chr4:8740998-8741542 4 A1 UGA Mm.410534 Transcribed locus 334.8004 289.5139 282.6971 270.2477 247.4733 336.9329 216.2075 214.2630 376.2577 357.5589 185.3755 366.0580 94.3405 103.9116 94.5110 95.4112 100.2825 84.1238 1363991 1446626_at 16 B1|16 11.0 cM chr16:18321758-18322258 16 A3 UGA Mm.265990 27883 D16H22S680E DNA segment, Chr 16, human D22S680E, expressed (D16H22S680E), mRNA 30.7348 27.8436 32.9400 37.8809 32.2596 32.2961 66.9384 68.8245 72.0407 69.9117 77.4685 62.5046 34.3475 29.0441 38.7380 33.7194 43.0985 42.9555 1364283 1446929_at chr4:32333019-32333404 4 A5 IPA Mus musculus 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130062J21 product:hypothetical protein, full insert sequence. 33.7704 32.9253 28.4348 31.7003 33.4418 40.7583 91.9000 98.3205 112.8971 108.4463 96.0602 108.3843 29.7202 48.1468 46.0258 31.8773 38.5551 46.3896 1364301 1446947_at chr2:135743824-135744212 2 F3 IPA Unknown 37.1200 54.2709 29.7453 41.1126 40.4528 40.1837 560.5491 570.3365 295.0376 305.6392 560.1990 295.1431 50.5778 98.3293 61.1347 77.1344 78.8355 77.4250 1364367 1447016_at 5 chr5:64550855-64565499 5 C3.1 RSQ XM_001476849 1 1 100046817 LOC100046817 PREDICTED: hypothetical protein LOC100046817 (LOC100046817), mRNA. 95.5052 76.9258 69.9392 77.6037 68.6925 77.4155 71.0820 80.9267 173.5964 195.1596 72.7367 164.1151 73.2654 84.5402 58.3413 91.0637 86.2893 89.4989 1364374 1447023_at chr14:18606024-18606518 14 A2 IPA ESTs 81.4323 103.5250 99.0628 84.4787 106.8753 82.4330 93.2839 97.7725 71.5846 72.2123 87.8000 89.0868 36.4919 31.7171 42.3399 33.5884 40.8376 40.9829 1364419 1447071_at chr19:55849331-55849773 19 D2 IPA Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230007B16 product:unknown EST, full insert sequence. 21.4697 27.1982 19.7839 19.0890 23.5970 21.7615 51.0538 40.4049 38.5660 36.8253 38.6752 41.6765 22.5291 19.4489 16.1454 15.7512 17.0158 18.2765 1364442 1447096_at 1 UGA Mm.395135 Transcribed locus 13.9648 14.5341 16.1145 15.3991 12.3485 15.6880 13.8693 22.9534 28.9957 55.7832 14.2759 35.3177 13.7650 12.2680 10.6671 10.1603 12.0090 11.5744 1364676 1447360_at 14 D3|14 42.0 cM chr14:76821285-76821639 14 D3 UGA Mm.153272 21807 Tsc22d1 TSC22-related inducible leucine zipper 1b (Tilz1b) cytoplasm;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 60.2610 88.5999 55.3514 49.8311 54.3169 78.3500 106.9335 122.7080 120.0449 117.2486 111.0269 100.6070 48.2031 40.0111 58.8073 52.8367 59.8079 45.2108 1364823 1447527_at chr8:47839851-47840054 8 B1.1 IPA ESTs 8.9159 13.2817 9.3842 9.4477 11.6057 12.7797 16.3480 24.5511 26.3198 23.8867 19.4500 23.4200 10.6801 12.4197 12.1738 18.4373 12.7972 12.4922 1364860 1447575_at chr1:162851522-162851657 1 H2.1 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 31.9917 32.2208 42.3948 34.2168 36.6746 37.2588 195.1244 198.8168 462.8211 440.0609 192.7568 415.9858 169.7343 138.0403 260.0653 177.5963 295.6453 124.1355 1372117 1447830_s_at 1 78.0 cM chr1:145847885-145847980 1 F chr1:145846467-145851279 1 F RSQ Mm.28262 NM_009061 1 1 19735 AL592303.1 Rgs2 regulator of G-protein signaling 2 (Rgs2), mRNA. brown fat cell differentiation;; cell cycle;; G-protein coupled receptor protein signaling pathway;; GTPase activator activity;; negative regulation of signal transduction;; nucleus;; signal transducer activity;; spermatogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle enzyme regulator activity;; molecular transducer activity enzyme activator activity;; nucleoside-triphosphatase regulator activity;; signal transducer activity biological regulation;; cellular process;; developmental process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process cell communication;; cell cycle;; cellular developmental process;; gamete generation;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; reproductive process;; sexual reproduction 19.8139 26.4231 27.8198 21.9803 21.2348 21.0276 3872.9896 3869.2951 1616.6509 1907.4264 3842.8185 1945.8741 306.4852 413.5158 330.5900 680.4346 707.2991 497.9465 1364970 1447891_at IPA Unknown 154.9522 107.1431 103.4462 109.7702 96.8413 75.1002 127.2222 203.5696 226.7805 303.7478 128.8888 289.4294 83.2405 76.5998 64.7923 64.9612 65.0472 88.4698 1372187 1447937_a_at 4 RSQ Mm.440578 NM_178649 15 15 108816 RP23-388P16.10 4933409K07Rik RIKEN cDNA 4933409K07 gene (4933409K07Rik), mRNA. 243.5958 286.7702 217.9292 295.9845 255.2075 277.6112 228.8484 205.9848 285.9852 273.2757 221.1514 294.7952 131.6773 124.0359 105.2715 114.6938 100.0341 144.8624 1372188 1447939_a_at 4 RSQ XM_001472444 14 14 100039323 LOC100039323 PREDICTED: similar to 4933409K07Rik protein (LOC100039323), mRNA. 97.0200 100.5597 71.4778 109.9291 105.1672 84.5122 134.4837 144.7839 360.5110 306.5686 157.2401 345.4387 88.6647 110.6624 107.6649 98.9603 99.8188 112.5430 1365491 1453368_at 11 E2 chr11:120237523-120238045 11 E2 UGA Mm.476851 71885 RP23-82I5.4 2310003H01Rik RIKEN cDNA 2310003H01 gene, mRNA (cDNA clone MGC:37540 IMAGE:4986832) DNA binding;; DNA repair;; nucleus;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding cellular process;; metabolic process;; response to stimulus cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to stress 25.9416 45.9415 37.1338 24.7919 25.4186 43.3832 270.1845 275.2630 287.2504 328.2888 275.4620 282.9922 54.0427 109.4001 110.4763 71.8476 122.6409 84.6470 1365603 1453512_at chr14:120797869-120798366 14 E4 IPA 5430437C10Rik RIKEN cDNA 5430437C10 gene 39.0723 34.0339 38.2199 44.3574 54.0238 37.3065 119.0483 133.2581 132.3713 137.5987 133.3976 131.0525 75.2414 65.5980 58.3114 61.5283 58.5704 55.2770 1365654 1453586_at 19 C3|19 35.5 cM chr19:40816546-40816931 19 C3 UGA Mm.2824 12495 Entpd1 Ectonucleoside triphosphate diphosphohydrolase 1, mRNA (cDNA clone MGC:18369 IMAGE:3674983) Purine metabolism;; Pyrimidine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] ATP binding;; ATP catabolic process;; basal lamina;; calcium ion binding;; G-protein coupled receptor protein signaling pathway;; hydrolase activity;; integral to membrane;; magnesium ion binding;; membrane;; nucleoside-diphosphatase activity;; nucleoside-triphosphatase activity;; nucleotide binding;; platelet activation;; purine ribonucleoside diphosphate catabolic process cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular matrix part;; extracellular region part;; membrane;; membrane part binding;; catalytic activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus catabolic process;; cell activation;; cell communication;; cellular metabolic process;; coagulation;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; response to external stimulus;; response to stress 19.9664 23.5997 20.3706 23.8969 18.4864 19.6150 89.0823 103.1829 67.2531 77.9309 102.7695 63.2674 31.2060 31.8963 38.5491 29.7178 35.8548 37.7594 1365738 1453698_at 4 UGA Mm.447147 Transcribed locus 38.7630 32.4297 24.7154 38.9361 31.2190 28.0886 203.0790 243.3040 268.2098 250.8772 240.4023 279.6841 104.7508 103.7209 119.0754 92.3646 118.5636 83.9307 1366017 1454141_at 10 chr10:69393723-69394253 10 B5.3 chr10:69393067-69394318 10 B5.3 RSQ XM_001474884 2 1 70557 5730416O20Rik PREDICTED: RIKEN cDNA 5730416O20 gene (5730416O20Rik), mRNA. 435.0837 654.5905 527.7025 421.0812 442.3402 694.2221 584.2596 610.4368 657.6373 646.6573 577.3216 650.9016 237.8351 217.2338 239.8541 339.2896 330.2852 429.0169 1366125 1454295_at 16 chr16:76351867-76352420 16 C3.1 UG5 Mm.453339 Transcribed locus 34.1027 35.4010 38.7901 49.2704 66.1193 62.0110 154.6579 176.0751 153.7784 175.3208 159.3666 197.9001 77.9389 95.8048 87.0499 86.3097 108.7159 80.9037 1366219 1454397_at 9 chr9:122038549-122039068 9 F4 IPA 4632418H02Rik RIKEN cDNA 4632418H02 gene 59.2568 57.6561 67.2984 64.8800 52.3928 59.4924 103.3378 94.9495 181.2528 219.4959 114.0118 214.4458 60.1656 71.6286 78.3818 54.6974 69.9339 66.0961 1366240 1454418_at 10 chr10:5322449-5322840 10 A1 UGA Mm.403826 Transcribed locus 18.4807 20.3811 22.2198 28.8419 17.5167 18.4864 56.6816 47.6452 379.9297 338.0776 57.2635 368.4297 68.6281 77.4844 179.4429 28.0236 16.7551 28.4394 1366492 1454768_at 12 chr12:17179290-17179470 12 A1.1 chr12:17178905-17183694 12 A1.1 RSQ Mm.40173 NM_201531 1 1 382571 Kcnf1 potassium voltage-gated channel, subfamily F, member 1 (Kcnf1), mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 128.8294 159.7612 136.1038 144.1433 198.4227 171.5408 466.6575 505.7755 524.4297 519.3554 453.5943 503.9401 270.0684 222.6845 251.7837 214.2438 290.3506 248.6901 1366823 1455345_at 11 chr11:51626974-51627488 11 B1.3 chr11:51626957-51670983 11 B1.3 RSQ Mm.259996 NM_199299 1 1 76901 RP23-79E13.10 Phf15 PHD finger protein 15 (Phf15), mRNA. metal ion binding;; protein binding;; zinc ion binding binding ion binding;; protein binding 52.5190 58.7155 53.6219 60.8516 56.6032 49.3592 461.7847 447.4748 537.8785 522.5164 444.7372 600.0966 200.6960 225.1912 235.2075 180.7945 231.4670 221.5834 1366899 1455455_at 3 chr3:85673879-85674282 3 F1 chr3:85673767-85691315 3 F1 RSQ Mm.119926 NM_177130 1 1 320302 Glt28d2 glycosyltransferase 28 domain containing 2 (Glt28d2), mRNA. Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; N-Glycan biosynthesis [PATH:mmu00510];; N-Glycan biosynthesis transferase activity catalytic activity transferase activity 289.6860 217.8068 297.6834 245.2232 359.2509 291.5820 323.3480 312.9609 562.7526 486.0086 330.9818 485.1085 164.8760 115.1972 132.5023 147.9682 111.6427 84.0424 1367030 1455660_at 15 43.3 cM chr15:78180890-78181373 15 E1 chr15:78156419-78181431 15 E1 RSQ Mm.235324 NM_007780 1 1 12983 Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), mRNA. IL 3 signaling pathway Apoptosis;; Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] cytokine receptor activity;; cytokine-mediated signaling pathway;; integral to membrane;; membrane;; protein binding;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 114.4566 133.3156 117.8427 136.7485 100.2422 139.9021 315.2422 293.4688 368.4962 432.4236 313.1209 366.2865 124.2635 121.3586 151.3185 126.8402 137.4310 137.7956 1367275 1456160_at 11 UG5 Mm.455208 Transcribed locus 270.9943 281.1240 270.6880 253.4030 281.7593 256.1429 719.2288 725.2630 554.0339 506.9572 795.3966 542.5408 159.9594 135.2528 132.1863 130.1038 145.5268 176.3627 1372399 1456209_x_at 7 chr7:71051754-71051840 7 C UGA Mm.446212 Transcribed locus 21.5748 22.4026 21.7940 17.5529 19.9503 17.7521 619.9110 631.0093 651.0070 597.1829 639.9392 603.8444 228.6287 247.9022 220.5377 226.2746 237.0717 232.4542 1367413 1456413_at 3 chr3:97569364-97569821 3 F2.2 UGA Mm.443527 Transcribed locus 125.3745 138.7075 157.2630 87.2372 149.0408 136.3001 1145.4934 1305.5997 994.4896 946.4901 1295.9852 946.0183 515.6465 449.6216 471.5172 402.7080 535.7531 502.0988 1367516 1456610_at 11 chr11:69213540-69214277 11 B3 chr11:69212009-69227177 11 B3 RSQ Mm.261201 NM_001017426 1 1 216850 RP23-5O23.5 Kdm6b KDM1 lysine (K)-specific demethylase 6B (Kdm6b), mRNA. chromatin modification;; histone demethylation;; inflammatory response;; iron ion binding;; metal ion binding;; negative regulation of transcription from RNA polymerase II promoter;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; sequence-specific DNA binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; response to stress 84.7071 128.8188 96.4418 106.8645 136.1541 103.3243 147.7504 142.5665 224.9293 173.6471 148.1232 179.1942 77.9540 85.6518 114.2956 77.2417 98.1641 113.7458 1367597 1456761_at 16 chr16:18831001-18831530 16 A3 UGA Mm.440786 Transcribed locus 10.4793 14.6916 18.3893 18.0748 11.9143 14.7118 72.7277 79.6896 165.3645 186.3418 84.3333 180.2684 73.0591 62.1333 88.4579 96.8324 123.7355 68.6730 1367622 1456789_at 4 chr4:55095838-55096382 4 B3 chr4:54960816-55096435 4 B3 RSQ Mm.102904 NM_172867 1 1 242466 RP23-281K3.2 Zfp462 zinc finger protein 462 (Zfp462), mRNA. negative regulation of DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 54.9635 57.7308 54.3340 66.5210 73.1637 58.0377 347.6708 313.3497 428.3287 391.7463 310.7599 434.3742 207.4813 186.6610 190.9852 217.8456 220.6128 249.8684 1367685 1456854_at 19 C3|19 49.25 cM chr19:47317619-47318055 19 C3 UG5 Mm.313651 18011 Neurl1a Neuralized 1 cytoplasm;; cytoplasm;; lactation;; metal ion binding;; nucleus;; plasma membrane;; protein binding;; response to external stimulus;; sperm axoneme assembly;; sperm motility;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding ion binding;; protein binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; localization;; locomotion;; multicellular organismal process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell motility;; cell motion;; cell projection organization;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; gamete generation;; localization of cell;; microtubule-based process;; multicellular organism reproduction;; multicellular organismal development;; organelle organization;; reproductive process;; reproductive process in a multicellular organism;; response to external stimulus;; sexual reproduction 71.8209 72.9219 75.7856 74.1900 87.0488 77.7457 2969.6121 3010.1049 3018.6502 2920.5796 3136.9788 2704.4297 1090.2856 868.2243 1032.8851 922.8981 834.6489 1035.6519 1367712 1456888_at 9 F2 chr9:108934151-108934674 9 F2 UGA Mm.132391 270198 Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 splice isoform 7 (Pfkfb4) mRNA, complete cds, alternatively spliced Fructose and mannose metabolism CLASS Metabolism; Carbohydrate Metabolism; Fructose and mannose metabolism [PATH:mmu00051] 6-phosphofructo-2-kinase activity;; ATP binding;; catalytic activity;; fructose 2,6-bisphosphate metabolic process;; fructose metabolic process;; fructose-2,6-bisphosphate 2-phosphatase activity;; hydrolase activity;; kinase activity;; metabolic process;; nucleotide binding;; transferase activity binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; transferase activity metabolic process alcohol metabolic process;; primary metabolic process 199.1744 203.5657 201.7950 163.4784 187.8263 189.8409 1076.7591 1076.0469 1157.7521 1101.0450 1078.8631 1092.7850 428.7722 571.1810 659.5363 500.0191 690.9045 863.3084 1367733 1456909_at 7 B1|7 11.0 cM chr7:35000258-35000824 7 B1 UGA Mm.589 14751 RP23-349I9.4 Gpi1 Glucose phosphate isomerase 1 (Gpi1), mRNA Glycolysis / Gluconeogenesis;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [PATH:mmu00030] Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism [PATH:mmu00500];; Pentose phosphate pathway;; Starch and sucrose metabolism angiogenesis;; cytokine activity;; cytoplasm;; extracellular region;; extracellular space;; gluconeogenesis;; glucose metabolic process;; glucose-6-phosphate isomerase activity;; glucose-6-phosphate isomerase activity;; glycolysis;; growth factor activity;; isomerase activity;; protein binding cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular part binding;; catalytic activity isomerase activity;; protein binding anatomical structure formation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process alcohol metabolic process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; catabolic process;; cellular metabolic process;; multicellular organismal development;; primary metabolic process 26.2271 32.4610 27.8286 22.0004 22.6352 27.9817 282.7037 293.1244 266.8480 322.6806 289.3290 359.8894 66.1316 78.5873 93.3656 77.6777 103.2862 89.6828 1367751 1456927_at 4 chr4:116008060-116008445 4 D1 UGA Mm.439252 Transcribed locus 137.3308 86.7837 103.0501 120.0740 226.1805 87.3251 589.1180 542.5408 357.9297 380.2292 599.7491 394.9972 152.1946 183.3186 194.6047 141.6304 163.0517 162.9297 1367806 1456986_at IPA Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430208D19 product:unknown EST, full insert sequence. 7.4116 7.5204 7.3875 7.7881 8.2728 7.5448 41.0669 66.6873 18.7084 22.4825 54.4917 22.8474 9.0663 10.5879 10.0793 9.9795 10.1156 9.1523 1367837 1457018_at 14 A3 chr14:24240872-24241001 14 A3 UGA Mm.343607 16531 Kcnma1 Calcium-activated potassium channel SLO1 mRNA, complete cds, alternatively spliced Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] adult walking behavior;; apical plasma membrane;; auditory receptor cell differentiation;; binding;; calcium ion binding;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; catalytic activity;; cell maturation;; circadian rhythm;; cytoplasmic part;; endoplasmic reticulum;; external side of plasma membrane;; eye blink reflex;; integral to membrane;; integral to membrane;; ion channel activity;; ion transport;; large conductance calcium-activated potassium channel activity;; large conductance calcium-activated potassium channel activity;; locomotor rhythm;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; micturition;; negative regulation of cell volume;; neuromuscular process controlling balance;; plasma membrane;; postsynaptic membrane;; potassium channel activity;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; protein homooligomerization;; regulation of action potential in neuron;; regulation of aldosterone metabolic process;; regulation of membrane potential;; regulation of membrane potential;; relaxation of vascular smooth muscle;; response to hypoxia;; saliva secretion;; sensory perception of sound;; sensory perception of sound;; smooth muscle contraction involved in micturition;; synaptic transmission;; terminal button;; transport;; vasodilation;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex;; organelle;; synapse;; synapse part apical part of cell;; cell part;; cell projection;; cell projection part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; postsynaptic membrane;; protein complex;; synapse part binding;; catalytic activity;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus;; rhythmic process adult behavior;; anatomical structure development;; behavior;; biosynthetic process;; cell communication;; cellular component assembly;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; circadian rhythm;; developmental maturation;; digestion;; establishment of localization;; hormone metabolic process;; macromolecular complex subunit organization;; multicellular organismal development;; negative regulation of biological process;; negative regulation of multicellular organismal process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress;; rhythmic behavior;; system process;; transport 102.3124 112.9872 101.9686 111.1434 122.3737 129.0637 287.3496 302.0509 244.9672 207.5398 280.0951 230.7607 79.9442 71.9231 88.4681 81.3939 131.3736 149.4576 1367839 1457022_at chrX:80383845-80383937 X C1 IPA ESTs, Weakly similar to POL2_MOUSE Retrovirus-related POL polyprotein [Contains: Reverse transcriptase ; Endonuclease] [M.musculus] 25.4892 23.8557 23.9333 16.6857 22.3200 24.0870 75.5634 68.5554 63.3319 71.8618 79.1126 77.7923 29.2716 27.5044 34.7240 28.6597 25.7304 24.5257 1367851 1457035_at 1 chr1:175653611-175655251 1 H3 chr1:175653558-175671940 1 H3 RSQ Mm.440876 XM_980696 3 2 226691 AI607873 PREDICTED: expressed sequence AI607873 (AI607873), mRNA. 22.9310 23.2014 21.8520 25.3330 28.9278 26.5094 27.1541 23.6099 38.4873 72.1122 25.8474 40.8092 19.8031 22.7469 21.0131 17.5786 20.7400 22.4447 1368013 1457206_at 18 chr18:14059095-14059646 18 A1 UG5 Mm.446738 Transcribed locus 83.7634 82.2538 89.0938 98.3949 95.7379 97.6393 93.9620 79.8308 170.0468 180.3741 93.9311 144.4899 73.7131 67.2953 60.8010 76.1898 68.2682 87.9793 1368059 1457262_at 7 chr7:125276822-125277367 7 F2 chr7:125274825-125387151 7 F2 RSQ Mm.309053 NM_001031814 1 1 233789 Smg1 SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) (Smg1), mRNA. ATP binding;; cytoplasm;; DNA repair;; kinase activity;; manganese ion binding;; metal ion binding;; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;; nucleotide binding;; nucleus;; phosphotransferase activity, alcohol group as acceptor;; protein serine/threonine kinase activity;; response to DNA damage stimulus;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process;; response to stimulus catabolic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to stress 73.8523 85.1890 79.7296 87.2932 106.8324 90.8402 395.3050 342.7759 395.4564 401.4318 362.0721 337.5892 34.1163 50.4593 39.9114 41.6182 83.8391 42.3097 1368114 1457324_at 4 UGA Mm.444175 Transcribed locus 50.6668 55.9587 46.9662 52.6370 69.7801 53.6138 47.5848 47.4742 80.7066 96.7529 51.7688 102.2285 43.2562 43.9795 48.1622 39.0504 39.7002 41.9251 1368132 1457342_at 10 chr10:128067933-128068329 10 D3 UGA Mm.441878 Transcribed locus 183.3186 192.0447 185.3186 127.6207 174.8168 204.5964 85.9078 88.0140 90.5595 95.8919 84.0571 103.3047 40.0596 55.5982 44.8582 38.4825 44.7501 53.3125 1368146 1457357_at 11 E1 chr11:105072019-105072545 11 E1 UGA Mm.126976 24086 RP23-456M3.2 Tlk2 Tousled-like kinase 2 (Arabidopsis) (Tlk2), transcript variant B, mRNA ATP binding;; cell cycle;; cell differentiation;; chromatin modification;; kinase activity;; multicellular organismal development;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; response to DNA damage stimulus;; spermatogenesis;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; reproduction;; reproductive process;; response to stimulus cell cycle;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; primary metabolic process;; reproductive process;; response to stress;; sexual reproduction 60.2408 60.8098 54.2975 59.3671 67.8229 52.9993 87.0100 90.4865 230.8186 137.4960 95.1100 128.2968 68.7537 77.4293 75.9167 66.6736 61.7678 84.2062 1368219 1457438_at 4 chr4:11053599-11054027 4 A1 UGA Mm.102270 Transcribed locus 176.4505 250.0297 284.8186 200.2489 200.7949 236.6874 226.9249 245.8434 247.2075 244.2311 226.6904 240.1555 95.2211 95.9989 135.8940 110.5941 164.9943 138.7956 1368238 1457458_at 7 A2 chr7:16987911-16988281 7 A2 UGA Mm.333594 330474 Zc3h4 Zinc finger CCCH-type containing 4 (Zc3h4), mRNA metal ion binding;; nucleic acid binding;; zinc ion binding binding ion binding;; nucleic acid binding 167.7576 161.2004 175.5293 189.7103 204.8956 184.8478 735.0825 736.7864 523.5302 546.9647 793.6734 523.2260 226.2160 245.5520 241.0075 317.4966 326.0545 248.4035 1368255 1457477_at 14 chr14:120728076-120728467 14 E4 UGA Mm.412819 Transcribed locus 353.5964 528.2160 420.6936 280.8904 371.0930 375.2450 65.6411 77.9205 76.6594 70.6932 72.2576 68.8587 28.2239 32.8415 34.8775 34.7206 57.2727 51.9185 1368293 1457515_at chr3:103569718-103570218 3 F2.2 IPA Mus musculus 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430065F18 product:unknown EST, full insert sequence. 52.9187 66.8732 67.9736 65.1223 72.2748 67.8863 314.3741 286.8186 332.6064 269.3753 328.9385 270.7975 93.5864 87.3115 98.2182 106.8774 152.7630 156.7890 1368327 1457553_at chr2:6739802-6740289 2 A1 IPA Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630035A22 product:unknown EST, full insert sequence. 41.7646 47.9265 39.3745 41.4570 58.4072 43.8871 85.8866 86.7986 65.1958 55.4062 65.1586 53.1068 26.0696 23.8722 30.4157 25.9339 24.2638 28.8316 1368349 1457575_at 2 chr2:52734850-52735317 2 C1.1 UGA Mm.26187 Transcribed locus 62.7820 59.9149 48.0966 54.8053 66.2596 55.9715 104.4957 104.2635 102.3942 183.7006 84.3457 270.9852 26.6840 28.9007 30.3025 24.2642 27.3846 33.4477 1368500 1457770_at 14 D2 chr14:70711457-70711852 14 D2 UGA Mm.270647 213053 Slc39a14 Solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 3, mRNA ferrous iron transmembrane transporter activity;; integral to membrane;; ion transport;; iron ion transport;; membrane;; metal ion transmembrane transporter activity;; metal ion transport;; plasma membrane;; transport;; zinc ion binding;; zinc ion transmembrane transporter activity;; zinc ion transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 83.6656 54.6698 58.5876 70.1822 96.8962 57.8087 75.2741 83.1943 145.3964 140.6163 81.0366 155.7489 73.8853 45.8964 84.8610 84.3949 100.9142 91.4226 1368595 1457877_at 10 chr10:5471012-5471471 10 A1 UGA Mm.445735 Transcribed locus 225.5678 256.9217 240.4976 211.0820 257.4944 292.8848 108.5489 110.9075 158.9917 133.7443 107.6649 140.6477 75.1392 71.6982 61.2466 68.3507 82.5394 112.7207 1368617 1457901_at chr4:136909787-136910353 4 D3 IPA ESTs, Weakly similar to S57243 collagen alpha 1(I) chain precursor - mouse [M.musculus] 425.0282 581.1367 622.1955 434.9775 553.7075 569.1085 649.3225 637.4060 683.1545 592.0586 655.8977 642.3201 179.5045 222.8387 231.4087 218.0542 290.3186 322.8936 1368639 1457924_at 3 chr3:60305173-60433670 3 D RSQ Mm.255723 NM_020007 2 2 56758 Mbnl1 muscleblind-like 1 (Drosophila) (Mbnl1), mRNA. cytoplasm;; metal ion binding;; mRNA splice site selection;; nucleic acid binding;; nucleus;; nucleus;; regulation of alternative nuclear mRNA splicing, via spliceosome;; RNA binding;; skeletal muscle tissue development;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; ribonucleoprotein complex biogenesis 47.9541 41.6124 50.0586 50.2804 58.0154 41.8546 204.1420 201.1247 345.1150 278.5408 183.2335 274.5788 50.4674 62.8800 46.2785 36.9569 48.9872 51.0452 1368796 1458089_at 17 chr17:28572812-28573322 17 A3.3 UGA Mm.445012 Transcribed locus 34.4671 53.2829 25.2206 27.6996 35.5422 34.6363 104.8685 151.4088 54.9064 87.2790 92.1797 88.0691 23.8277 27.9698 35.8988 30.7100 24.6927 28.2550 1368999 1458308_at 10 C1 chr10:79529116-79529307 10 C1 UG5 Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 94.2228 142.4853 121.1446 128.2756 162.8795 97.4343 1230.5408 1253.7421 826.8973 752.7224 1190.2159 726.8833 237.4021 298.0962 372.0275 410.5964 520.1011 417.5446 1369044 1458376_at 14 chr14:120740319-120740808 14 E4 UGA Mm.440488 Transcribed locus 83.2874 100.3066 91.9279 101.5437 106.7119 112.5634 255.0898 229.1534 647.8549 746.7632 238.5366 809.0697 89.7467 99.4203 90.6606 76.0075 79.1880 92.4345 1369075 1458409_at chr14:55370840-55371308 14 C3 IPA ESTs 67.5451 71.7479 72.9071 56.4250 62.4463 52.7657 374.5250 329.3741 303.4438 289.2736 364.9433 294.6756 143.5014 133.5125 127.4139 138.6086 155.7949 156.4852 1369131 1458469_at chr16:52052604-52053123 16 B5 IPA ESTs 137.2218 148.9066 113.4052 133.7818 106.7316 156.5887 109.5039 101.7991 165.1664 166.0134 116.1546 166.9110 84.2446 67.7992 70.8158 66.0730 62.1821 80.3640 1369180 1458520_at 6 chr6:38689135-38689584 6 B1 UGA Mm.441552 Transcribed locus 81.7963 94.0051 75.6597 63.4866 81.2168 98.5762 391.1069 419.9036 196.8989 212.3617 398.2173 199.0408 91.3111 97.5678 108.4098 113.1539 123.8218 126.5902 1369619 1458969_at chr8:11786297-11786741 8 A1.1 IPA ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 31.8715 26.0521 24.5370 23.8977 26.7087 25.0146 63.7484 67.6986 106.0001 103.6980 62.0948 110.9362 31.8715 36.2455 40.0374 33.6366 35.9590 32.8383 1369809 1459170_at chr3:52134457-52135011 3 C IPA ESTs 20.4556 36.5826 34.0727 28.4022 42.3494 30.0196 718.2914 714.1891 595.7968 588.5269 689.8825 592.4411 192.4447 271.7739 292.1328 210.0495 265.0699 169.5384 1369874 1459238_at chr10:53062351-53062774 10 B3 IPA ESTs 59.2510 61.6083 45.8150 51.2151 55.7988 45.1870 730.4230 720.9127 540.4141 504.3001 704.2392 515.4086 173.1913 229.7851 282.4886 104.2297 176.7560 163.6361 1370187 1459557_at chr9:48515954-48516379 9 A5.3 IPA ESTs 28.2135 39.0896 27.3603 25.9349 39.5737 30.6330 89.3458 99.2999 124.6053 127.1085 100.0732 137.5409 27.8495 28.7618 56.9326 30.8986 34.5226 34.6296 1370236 1459609_at chr8:79928865-79929131 8 C1 IPA Unknown 54.4747 60.4639 68.1473 50.6283 48.3955 60.3597 127.6944 125.5922 70.8882 85.7071 127.5473 81.8676 26.8483 35.5978 44.5682 27.6067 63.1479 43.9594 1370262 1459635_at IPA ESTs 19.4131 28.2425 26.7942 30.4874 29.1389 23.3485 47.1118 46.6243 53.2013 48.4369 59.0049 41.3416 23.9333 23.5786 23.2114 22.0541 29.4978 28.9616 1370313 1459691_at chr3:30077395-30077749 3 A3 IPA ESTs 50.4992 67.6828 43.3218 42.5387 55.6462 51.4793 51.0871 47.7558 78.3820 76.1671 49.0054 65.1483 32.5642 40.5039 32.2046 31.0515 38.9469 39.9373 1370414 1459887_at 9 UGA Mm.477617 Transcribed locus 64.4550 96.0641 65.4187 51.2704 77.0324 40.7573 224.7226 188.5562 162.6522 164.6721 214.4746 132.1016 74.4751 55.1390 69.2756 112.2798 103.0533 100.7714 1372677 1459961_a_at 11 D|11 60.5 cM chr11:100797327-100797529 11 D UGA Mm.249934 20848 RP23-279L23.5 Stat3 Signal transducer and activator of transcription 3, mRNA (cDNA clone IMAGE:3665873) EGF Signaling Pathway;; Erk1/Erk2 Mapk Signaling pathway;; IL 6 signaling pathway;; IL22 Soluble Receptor Signaling Pathway;; PDGF Signaling Pathway;; Role of ERBB2 in Signal Transduction and Oncology;; Signaling of Hepatocyte Growth Factor Receptor;; Stat3 Signaling Pathway;; TPO Signaling Pathway Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200];; Adipocytokine signaling pathway;; Chemokine signaling pathway;; Jak-STAT signaling pathway;; Pancreatic cancer;; Pathways in cancer acute-phase response;; calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; DNA binding;; eating behavior;; eye photoreceptor cell differentiation;; glucose homeostasis;; JAK-STAT cascade involved in growth hormone signaling pathway;; nucleus;; plasma membrane;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; protein dimerization activity;; protein kinase binding;; regulation of multicellular organism growth;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; sexual reproduction;; signal transducer activity;; signal transduction;; temperature homeostasis;; transcription;; transcription activator activity;; transcription factor activity;; transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to endogenous stimulus;; response to external stimulus;; response to stress;; sexual reproduction;; temperature homeostasis 59.2929 64.1092 71.7310 67.0772 83.3859 66.6362 130.6443 119.5124 86.6748 84.6133 120.0897 89.9929 43.6744 44.8343 39.9653 63.0145 68.2096 60.7607 1370550 1460099_at 18 chr18:81117895-81118449 18 E3 UGA Mm.440050 Transcribed locus