A 1 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen A 2 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen A 3 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen B 4 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen B 5 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen B 6 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen The input data set contained 45101 genes The filtered output data set contains 417 genes 36365 gene rows removed by Include where A-B T-test p-value (two tailed) <= 0.05 8319 gene rows removed by Include where A-B Mean Difference >= 1 A A A B B B 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen A-B p-Value A-B Mean Difference A Mean B Mean Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 771.4070 823.4967 793.6926 258.9766 312.4832 296.8349 0.0012979751 1.46386 9.63647 8.17261 1350144 AFFX-DapX-M_at IPA B. subtilis GEN=dapB, jojF DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2020-2580 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA- 1123.3146 1135.9661 1146.4961 276.9004 299.9979 301.1684 0.00023531283 1.95660 10.14876 8.19215 1350142 AFFX-DapX-3_at IPA B. subtilis GEN=jojG DB_XREF=gb:L38424.1 NOTE=SIF corresponding to nucleotides 2684-3130 of gb:L38424.1 DEF=Bacillus subtilis dihydropicolinate reductase (jojE) gene, complete cds; poly(A) polymerase (jojI) gene, complete cds; biotin acetyl-CoA-carbox 94.0622 72.1614 73.1738 30.4225 42.6698 38.3770 0.0046620416 1.10586 6.30732 5.20146 1350147 AFFX-LysX-M_at IPA B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 720-990 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). 252.8868 250.6604 257.3694 74.2549 85.4592 91.2351 0.0026049141 1.60551 7.98655 6.38103 1350145 AFFX-LysX-3_at IPA B. subtilis GEN=lys DB_XREF=gb:X17013.1 NOTE=SIF corresponding to nucleotides 1061-1343 of gb:X17013.1, not 100% identical DEF=B subtilis lys gene for diaminopimelate decarboxylase (EC 4.1.1.20). 600.1130 609.5262 592.6165 171.3071 198.3072 187.2436 0.00092384287 1.69693 9.23053 7.53360 1350152 AFFX-ThrX-3_at IPA B. subtilis GEN=thrB DB_XREF=gb:X04603.1 NOTE=SIF corresponding to nucleotides 1689-2151 of gb:X04603.1 DEF=B. subtilis thrB and thrC genes for homoserine kinase and threonine synthase (EC 2.7.1.39 and EC 4.2.99.2, respectively). 695.4387 754.7926 765.6097 205.4040 261.3741 236.2226 0.0010640835 1.66196 9.52739 7.86543 1350164 AFFX-r2-Bs-dap-M_at IPA 1426.4386 1566.0153 1615.3336 381.6481 426.0964 441.1519 2.6928887e-05 1.88414 10.58290 8.69876 1350162 AFFX-r2-Bs-dap-3_at IPA 82.9066 67.0102 56.7824 23.5507 26.1362 27.2546 0.0060167425 1.41100 6.08903 4.67803 1350166 AFFX-r2-Bs-lys-5_at IPA 78.7199 89.9643 109.7782 22.6137 24.2998 22.7872 0.0033483946 1.98541 6.52279 4.53738 1350167 AFFX-r2-Bs-lys-M_at IPA 83.7607 88.9093 103.2695 37.5249 37.8194 41.1492 0.0014106982 1.23970 6.51758 5.27787 1350165 AFFX-r2-Bs-lys-3_at IPA 99.0757 105.2021 114.1218 32.0442 30.2141 48.9383 0.014429227 1.54996 6.72730 5.17734 1350170 AFFX-r2-Bs-phe-M_at IPA 297.7630 305.2630 277.4852 101.2442 125.0812 150.8846 0.013406602 1.24083 8.19607 6.95524 1350168 AFFX-r2-Bs-phe-3_at IPA 644.7265 687.9365 650.3661 190.9367 216.9596 201.0347 7.9008989e-05 1.70475 9.36793 7.66318 1350180 AFFX-r2-Bs-thr-3_s_at IPA 2828.9401 3004.4966 3054.2322 998.1993 1552.2703 1420.2196 0.023115538 1.18677 11.53185 10.34508 1350161 AFFX-MURINE_b1_at IPA M. musculus GEN=b1 DB_XREF=gb:U01310.1 NOTE=SIF corresponding to nucleotides 5-75 of gb:U01310.1 DEF=Mus musculus C57 Black6 BC1 scRNA. 5396.0694 6217.8418 6334.4440 3439.9127 3280.8623 2312.6162 0.019109684 1.00852 12.54296 11.53444 1327781 1416041_at 10 chr10:21719153-21719585 10 A3 chr10:21705909-21719699 10 A3 RSQ NM_001161848 6 1 20393 Sgk1 serum/glucocorticoid regulated kinase 1 (Sgk1), transcript variant 3, mRNA. apoptosis;; ATP binding;; cellular response to insulin stimulus;; cytoplasm;; endoplasmic reticulum;; kinase activity;; nucleotide binding;; nucleus;; positive regulation of sodium ion transport;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; regulation of protein localization;; response to DNA damage stimulus;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity biological regulation;; cellular process;; death;; establishment of localization;; localization;; metabolic process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell death;; cellular metabolic process;; cellular response to stimulus;; establishment of localization;; macromolecule localization;; macromolecule metabolic process;; positive regulation of biological process;; positive regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of localization;; response to chemical stimulus;; response to endogenous stimulus;; response to stress;; transport 3740.2317 3792.1841 3776.1069 1193.3719 791.9517 1586.0958 0.027386625 1.71968 11.88014 10.16045 1327844 1416125_at 17 13.0 cM chr17:28536264-28536617 17 A3.3 chr17:28536039-28623057 17 A3.3 RSQ Mm.276405 NM_010220 1 1 14229 Fkbp5 FK506 binding protein 5 (Fkbp5), mRNA. binding;; cytoplasm;; isomerase activity;; nucleus;; peptidyl-prolyl cis-trans isomerase activity;; protein binding;; protein folding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1302.4297 1301.1519 1293.8646 637.1139 391.6131 424.6579 0.021489738 1.45706 10.34334 8.88628 1327847 1416129_at 4 chr4:150242409-150242794 4 E2 chr4:150229199-150242989 4 E2 RSQ Mm.318841 NM_133753 1 1 74155 RP23-272N19.4 Errfi1 ERBB receptor feedback inhibitor 1 (Errfi1), mRNA. cytoplasm;; cytosol;; protein binding;; receptor activity;; stress-activated protein kinase signaling pathway cell;; cell part cell part;; intracellular;; intracellular part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular response to stimulus;; regulation of biological process;; regulation of cellular process;; response to stress 802.0430 734.4321 702.4433 234.9824 228.5365 290.1378 0.0010117962 1.57699 9.54142 7.96443 1328194 1416576_at 11 chr11:117827755-117827967 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 942.3607 894.1517 921.0368 436.3086 403.7933 481.0253 0.0025452564 1.06499 9.84388 8.77888 1343360 1416708_a_at 7 13.0 cM chr7:31915193-31917633 7 B1 chr7:31915145-31936069 7 B1 RSQ Mm.27366 NM_027898 1 1 52857 Gramd1a GRAM domain containing 1A (Gramd1a), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 462.7434 452.3175 474.3021 225.1327 200.4297 210.4280 0.00048200969 1.12872 8.85497 7.72626 1328472 1416926_at 4 chr4:11101005-11101491 4 A1 chr4:11083587-11101524 4 A1 RSQ Mm.393018 NM_021897 1 1 60599 RP23-343F17.4 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Trp53inp1), mRNA. apoptosis;; cell cycle arrest;; cytoplasm;; induction of apoptosis;; nucleolus;; nucleus;; response to stress cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part biological regulation;; cellular process;; death;; developmental process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cell death;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 131.4061 153.2983 142.1691 67.3876 63.6202 66.7147 0.0010913745 1.10793 7.14985 6.04192 1328473 1416927_at 4 chr4:11098069-11098628 4 A1 chr4:11083587-11101524 4 A1 RSQ Mm.393018 NM_021897 1 1 60599 RP23-343F17.4 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Trp53inp1), mRNA. apoptosis;; cell cycle arrest;; cytoplasm;; induction of apoptosis;; nucleolus;; nucleus;; response to stress cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part biological regulation;; cellular process;; death;; developmental process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cell death;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 1023.5599 1065.2307 1082.9604 316.0087 330.1832 538.1445 0.02614576 1.46477 10.04570 8.58093 1328519 1416981_at 3 22.5 cM chr3:52149839-52150299 3 C chr3:52072258-52154031 3 C RSQ Mm.29891 NM_019739 1 1 56458 Foxo1 forkhead box O1 (Foxo1), mRNA. AKT Signaling Pathway Insulin signaling pathway;; Pathways in cancer;; Prostate cancer CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Prostate cancer [PATH:mmu05215] blood vessel development;; cytoplasm;; DNA binding;; insulin receptor signaling pathway;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to endogenous stimulus 886.9903 782.5951 793.7942 375.3186 315.7809 522.0165 0.031461117 1.05160 9.67917 8.62757 1328520 1416982_at 3 22.5 cM chr3:52152874-52153321 3 C chr3:52072258-52154031 3 C RSQ Mm.29891 NM_019739 1 1 56458 Foxo1 forkhead box O1 (Foxo1), mRNA. AKT Signaling Pathway Insulin signaling pathway;; Pathways in cancer;; Prostate cancer CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Prostate cancer [PATH:mmu05215] blood vessel development;; cytoplasm;; DNA binding;; insulin receptor signaling pathway;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to endogenous stimulus 1050.2357 1161.9311 1276.5964 368.5408 347.8397 484.8291 0.0023593481 1.54920 10.17896 8.62976 1343415 1416983_s_at 3 chr3:52153576-52154004 3 C UG5 Mm.395558 Transcribed locus 68.3060 96.8862 96.6891 39.8209 34.8730 50.1756 0.0095296588 1.06635 6.42915 5.36280 1328931 1417483_at 16 chr16:55811560-55812070 16 C1.1 chr16:55811489-55838754 16 C1.1 RSQ NM_001159395 3 1 80859 Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 3, mRNA. inflammatory response;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; response to stress 491.9685 443.1550 480.8783 198.0915 196.9632 222.7773 0.00011990886 1.19745 8.88121 7.68375 1329033 1417600_at 16 chr16:36750284-36750836 16 B3 chr16:36750249-36785048 16 B3 RSQ Mm.281804 NM_021301 1 1 57738 Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 (Slc15a2), transcript variant 1, mRNA. high affinity oligopeptide transporter activity;; integral to membrane;; integral to plasma membrane;; membrane;; membrane fraction;; oligopeptide transport;; oligopeptide transporter activity;; peptide transport;; protein transport;; symporter activity;; transport;; transporter activity cell;; cell part cell fraction;; cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 185.4859 161.3036 161.7408 53.7779 51.4322 60.4345 7.3825286e-05 1.61850 7.40211 5.78361 1329204 1417821_at 17 B1|17 19.0 cM chr17:35134509-35134926 17 B1 UG5 Mm.22506 110956 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942) viral envelope virion;; virion part viral envelope;; virion part 245.9297 260.7433 265.4801 101.8506 141.9652 129.9855 0.014090455 1.05971 8.00702 6.94730 1329205 1417822_at 17 B1|17 19.0 cM chr17:35133679-35134254 17 B1 UGA Mm.22506 110956 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5, mRNA (cDNA clone MGC:28170 IMAGE:3985942) viral envelope virion;; virion part viral envelope;; virion part 630.5303 733.3004 756.2393 131.8816 143.0271 185.3942 0.00081326801 2.21456 9.46046 7.24590 1329298 1417929_at 14 chr14:55341124-55341626 14 C3 chr14:55341051-55400723 14 C3 RSQ Mm.276831 NM_016972 1 1 50934 Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), mRNA. amine transmembrane transporter activity;; amino acid transmembrane transporter activity;; amino acid transport;; cytoplasm;; integral to membrane;; L-amino acid transmembrane transporter activity;; L-amino acid transport;; membrane;; plasma membrane;; transport cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 518.4976 537.2075 491.2858 208.1934 239.0579 231.8742 0.00024668048 1.18925 9.00932 7.82006 1329370 1418018_at 11 46.0 cM chr11:76595516-76598574 11 B5 chr11:76590709-76660510 11 B5 RSQ Mm.276736 NM_007754 2 2 12874 RP23-396O3.1 Cpd carboxypeptidase D (Cpd), mRNA. carboxypeptidase activity;; hydrolase activity;; integral to membrane;; membrane;; metal ion binding;; metallocarboxypeptidase activity;; metallopeptidase activity;; peptidase activity;; proteolysis;; serine-type carboxypeptidase activity;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity hydrolase activity;; ion binding metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 550.9603 512.3839 535.1430 247.4181 210.7387 268.4159 0.0047959966 1.14407 9.05689 7.91281 1329435 1418091_at 1 chr1:120581186-120581654 1 E2.3 chr1:120524521-120581745 1 E2.3 RSQ Mm.24621 NM_023755 1 1 81879 Tcfcp2l1 transcription factor CP2-like 1 (Tcfcp2l1), mRNA. cell morphogenesis;; cytoplasm;; cytoplasm organization;; determination of adult life span;; DNA binding;; epithelial cell maturation;; general transcriptional repressor activity;; membrane;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; positive regulation of growth;; regulation of transcription, DNA-dependent;; salivary gland development;; transcription;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; transcription repressor activity biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process aging;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; cytoplasm organization;; determination of adult life span;; developmental maturation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of growth;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process 427.7633 435.7528 410.1836 166.7667 204.1521 170.5035 0.0033247122 1.23977 8.72939 7.48961 1343611 1418094_s_at 11 chr11:84778338-84779387 11 C chr11:84771255-84779556 11 C RSQ Mm.1641 NM_007607 1 1 12351 RP23-167D6.1 Car4 carbonic anhydrase 4 (Car4), mRNA. Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] anchored to membrane;; carbonate dehydratase activity;; lyase activity;; membrane;; metal ion binding;; one-carbon metabolic process;; plasma membrane;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 230.0479 195.4947 203.1519 103.4615 83.0247 96.7651 0.00086638514 1.15279 7.70773 6.55494 1329468 1418133_at 7 A3|7 6.5 cM chr7:20393860-20394209 7 A3 UG5 Mm.439658 12051 Bcl3 B-cell leukemia/lymphoma 3 (Bcl3), mRNA antimicrobial humoral response;; defense response to bacterium;; defense response to protozoan;; DNA binding;; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;; extracellular matrix organization;; follicular dendritic cell differentiation;; germinal center formation;; humoral immune response mediated by circulating immunoglobulin;; marginal zone B cell differentiation;; negative regulation of apoptosis;; negative regulation of apoptosis;; negative regulation of tumor necrosis factor biosynthetic process;; nucleus;; positive regulation of interferon-gamma production;; positive regulation of interleukin-10 biosynthetic process;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription, DNA-dependent;; spleen development;; T-helper 1 type immune response;; T-helper 2 cell differentiation;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell communication;; cell death;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; cytokine production;; extracellular structure organization;; immune effector process;; immune response;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to biotic stimulus;; response to other organism;; response to stress 400.5288 415.3885 399.0308 170.6553 220.1440 217.9486 0.012416259 1.00645 8.66148 7.65503 1329642 1418349_at 18 15.0 cM chr18:36664709-36665151 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 1087.2290 1016.1770 1001.6325 229.5814 352.9350 339.5979 0.01027263 1.77657 10.01450 8.23793 1329643 1418350_at 18 15.0 cM chr18:36665688-36667226 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 1720.5622 1620.5964 1608.2665 348.9983 559.5430 674.1314 0.025497264 1.69673 10.68742 8.99069 1329744 1418469_at 16 C3.1 chr16:76290241-76290637 16 C3.1 UGA Mm.455873 268903 Nrip1 Receptor interacting protein 140 histone deacetylase binding;; histone deacetylase complex;; lipid storage;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; ovarian follicle rupture;; ovulation;; protein binding;; receptor activity;; receptor binding;; regulation of transcription, DNA-dependent;; retinoid X receptor binding;; transcription;; transcription corepressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity protein binding;; signal transducer activity;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; biosynthetic process;; cellular metabolic process;; gamete generation;; macromolecule localization;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 8486.7441 8234.3186 8334.2463 4128.7749 3842.1831 4311.7755 0.0012546747 1.03000 13.02776 11.99776 1329836 1418595_at 17 chr17:56240045-56240601 17 D chr17:56240013-56249225 17 D RSQ Mm.476969 NM_020568 1 1 57435 S3-12 plasma membrane associated protein, S3-12 (S3-12), mRNA. cytoplasm;; lipid particle;; membrane;; plasma membrane cell;; cell part cell part;; intracellular;; intracellular part;; membrane 583.7400 589.9493 562.3837 220.9147 195.1858 237.3959 0.0020889572 1.41395 9.17635 7.76240 1329909 1418674_at 15 4.6 cM chr15:6763697-6764043 15 A1 chr15:6763576-6824313 15 A1 RSQ Mm.10760 NM_011019 1 1 18414 Osmr oncostatin M receptor (Osmr), mRNA. Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] cell surface receptor linked signal transduction;; cytokine receptor activity;; integral to membrane;; integral to plasma membrane;; membrane;; oncostatin-M receptor activity;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 164.2244 143.9866 143.1606 82.8159 66.4872 73.7540 0.0013057104 1.01977 7.23027 6.21050 1329953 1418722_at 9 chr9:110324928-110325482 9 F2 chr9:110322311-110325516 9 F2 RSQ Mm.236225 NM_008694 1 1 18054 Ngp neutrophilic granule protein (Ngp), mRNA. cytoplasmic vesicle;; defense response to bacterium cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; vesicle multi-organism process;; response to stimulus response to biotic stimulus;; response to other organism;; response to stress 1520.8179 1569.7753 1507.4704 748.8586 587.7075 972.1469 0.038599475 1.02412 10.58163 9.55751 1330123 1418932_at 13 32.0 cM chr13:53062781-53063171 13 B1 chr13:53062577-53076408 13 B1 RSQ Mm.136604 NM_017373 2 2 18030 Nfil3 nuclear factor, interleukin 3, regulated (Nfil3), mRNA. DNA binding;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; rhythmic process;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; rhythmic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 388.5028 421.8766 406.3183 180.9722 179.6729 218.4654 0.0033312058 1.07627 8.66298 7.58670 1330208 1419034_at 2 chr2:152104805-152104961 2 G3 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 2 2 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 366.5053 363.7908 338.3349 170.1959 172.9852 180.6407 5.2522853e-05 1.02814 8.47565 7.44751 1343779 1419035_s_at 2 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 3 3 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 1285.4907 1195.2479 1176.4773 254.4146 504.5371 539.1170 0.043833992 1.56905 10.25049 8.68144 1343780 1419038_a_at 2 chr2:152052575-152107588 2 G3 RSQ Mm.23692 NM_007788 2 2 12995 RP23-452D3.3 Csnk2a1 casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. EGF Signaling Pathway;; EPO Signaling Pathway;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 6 signaling pathway;; Insulin Signaling Pathway;; Lissencephaly gene (LIS1) in neuronal migration and development;; Nerve growth factor pathway (NGF);; PDGF Signaling Pathway;; TPO Signaling Pathway;; WNT Signaling Pathway Adherens junction;; Tight junction CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Cell Communication; Adherens junction [PATH:mmu04520] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Wnt signaling pathway ATP binding;; beta-catenin binding;; kinase activity;; nucleotide binding;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase CK2 complex;; protein phosphatase regulator activity;; protein serine/threonine kinase activity;; transferase activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleotide binding;; phosphatase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 56.4478 58.8460 59.5199 19.3669 24.2580 22.2728 0.0029299836 1.41330 5.86434 4.45104 1343786 1419075_s_at 7 B4|7 23.5 cM UG5 Mm.200941 20209 Saa2 Serum amyloid A 2, mRNA (cDNA clone MGC:18481 IMAGE:3662957) acute-phase response;; extracellular region;; high-density lipoprotein particle;; protein binding extracellular region;; extracellular region part;; macromolecular complex extracellular region part;; extracellular space;; plasma lipoprotein particle;; protein-lipid complex binding protein binding response to stimulus response to external stimulus;; response to stress 810.9575 769.8051 836.9423 283.6139 377.9120 319.7924 0.0051131506 1.31004 9.65361 8.34356 1330251 1419088_at 10 C1|10 C1-D1|10 47.0 c chr10:85808696-85809146 10 C1 UG5 Mm.4871 21859 Timp3 Tissue inhibitor of metalloproteinase 3, mRNA (cDNA clone MGC:25359 IMAGE:4239015) Inhibition of Matrix Metalloproteinases;; p53 Signaling Pathway basement membrane;; enzyme inhibitor activity;; extracellular region;; metalloendopeptidase inhibitor activity;; proteinaceous extracellular matrix extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part enzyme regulator activity enzyme inhibitor activity;; metalloenzyme regulator activity 61.7159 61.2972 76.0614 21.2368 24.5026 25.2993 0.00046694083 1.48334 6.04480 4.56146 1330349 1419209_at 5 51.0 cM chr5:91321568-91321979 5 E1 chr5:91320270-91322147 5 E1 RSQ Mm.21013 NM_008176 1 1 14825 Cxcl1 chemokine (C-X-C motif) ligand 1 (Cxcl1), mRNA. Chemokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062];; Cytokine-cytokine receptor interaction chemokine activity;; cytokine activity;; extracellular region;; extracellular space;; growth factor activity;; immune response;; inflammatory response extracellular region;; extracellular region part extracellular region part;; extracellular space binding protein binding immune system process;; response to stimulus immune response;; response to external stimulus;; response to stress 2638.8732 2549.1249 2603.0837 1057.5133 1109.7197 1362.5183 0.0084971541 1.15100 11.34250 10.19150 1330359 1419220_at 9 F4 chr9:119923004-119923392 9 F4 UGA Mm.10117 22437 Xirp1 Xin actin binding;; actin cytoskeleton organization;; cardiac muscle cell development;; cell junction;; cell-cell adherens junction;; fascia adherens;; filamin-C binding;; heart morphogenesis;; intercalated disc;; negative regulation of cell proliferation;; protein binding;; regulation of membrane potential;; sarcomere organization cell;; cell part cell part;; membrane;; membrane part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular homeostasis;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of biological quality;; regulation of cellular process 642.7993 617.3973 674.2243 258.9297 414.8329 306.5692 0.033201684 1.00750 9.33179 8.32429 1330384 1419255_at 11 13.0 cM chr11:30007644-30008198 11 A3.3 chr11:30006842-30098257 11 A3.3 RSQ Mm.123110 NM_009260 1 1 20742 RP23-189P1.1 Spnb2 spectrin beta 2 (Spnb2), transcript variant 2, mRNA. Tight junction CLASS Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] actin binding;; actin filament capping;; calmodulin binding;; common-partner SMAD protein phosphorylation;; cortical cytoskeleton;; cytoplasm;; cytoskeleton;; membrane;; nucleus;; plasma membrane;; protein binding;; SMAD protein nuclear translocation;; spectrin;; structural constituent of cytoskeleton cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; structural molecule activity protein binding;; structural constituent of cytoskeleton anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cellular component assembly;; cellular component disassembly;; cellular localization;; cellular macromolecular complex subunit organization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecular complex subunit organization;; macromolecule localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of cellular component biogenesis;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; transport 1440.1093 1367.0532 1358.8526 583.2655 522.9783 471.7414 0.0020717143 1.40551 10.43900 9.03349 1330421 1419301_at 7 44.5 cM chr7:96557344-96557739 7 E1 chr7:96552875-96558620 7 E1 RSQ Mm.86755 NM_008055 1 1 14366 Fzd4 frizzled homolog 4 (Drosophila) (Fzd4), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Endocrine System; Melanogenesis [PATH:mmu04916] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210] Human Diseases; Cancers; Basal cell carcinom;; Colorectal cancer;; Melanogenesis;; Pathways in cancer;; Wnt signaling pathway cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; protein binding;; receptor activity;; signal transducer activity;; signal transduction;; transmembrane receptor activity;; Wnt receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 534.1462 515.8767 521.3794 24.1276 26.9098 61.2412 0.011317567 3.93969 9.03272 5.09304 1343853 1419394_s_at 3 43.6 cM chr3:90473446-90473926 3 F1 chr3:90472992-90473956 3 F1 RSQ Mm.21567 NM_013650 1 1 20201 S100a8 S100 calcium binding protein A8 (calgranulin A) (S100a8), mRNA. calcium ion binding;; chemotaxis binding ion binding locomotion;; response to stimulus behavior;; response to chemical stimulus;; response to external stimulus;; taxis 4102.5894 3903.8400 3935.7060 1541.0546 1934.3094 1800.4696 0.0047618432 1.18465 11.95847 10.77382 1330677 1419621_at 19 chr19:42116522-42119434 19 C3 chr19:42110527-42119600 19 C3 RSQ Mm.143737 NM_020033 1 1 56642 Ankrd2 ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA. I band;; nucleus;; sarcomere cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 270.4297 272.6499 267.0964 67.8707 89.4319 81.1819 0.0041251462 1.77357 8.07708 6.30351 1343918 1419700_a_at 5 chr5:44384916-44385436 5 B3 chr5:44384860-44492920 5 B3 RSQ Mm.6250 NM_008935 1 1 19126 Prom1 prominin 1 (Prom1), mRNA. apical plasma membrane;; brush border;; cell projection;; cell surface;; extracellular space;; integral to membrane;; integral to plasma membrane;; membrane;; microvillus;; plasma membrane;; stereocilium cell;; cell part;; extracellular region;; extracellular region part;; organelle;; organelle part apical part of cell;; cell part;; cell projection;; cell surface;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle;; organelle part;; stereocilium 942.8741 972.1465 926.7547 304.3540 372.3449 360.4899 0.002631604 1.45936 9.88733 8.42797 1343970 1419927_s_at 1 chr1:136403861-136404136 1 E4 chr1:136391236-136404462 1 E4 RSQ Mm.198119 NM_145510 1 1 98710 Rabif RAB interacting factor (Rabif), mRNA. guanyl-nucleotide exchange factor activity;; metal ion binding;; protein transport;; small GTPase mediated signal transduction;; transport;; zinc ion binding binding;; enzyme regulator activity ion binding;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; establishment of localization;; localization;; regulation of biological process cell communication;; establishment of localization;; establishment of protein localization;; macromolecule localization;; regulation of biological process;; regulation of cellular process;; transport 5887.2630 5463.7630 5389.6519 2455.4083 3278.0408 2486.8419 0.011615157 1.03819 12.44501 11.40682 1330965 1420088_at 12 C1-C3 chr12:56590464-56590506 12 C1 UGA Mm.170515 18035 Nfkbia Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 1009.0486 991.8128 992.4099 391.7701 515.2200 529.7199 0.016116858 1.07183 9.96250 8.89066 1331105 1420342_at 12 A3 chr12:33511200-33511722 12 A3 UGA Mm.440246 14546 Gdap10 Ganglioside-induced differentiation associated protein 10 response to retinoic acid response to stimulus response to chemical stimulus;; response to external stimulus 101.3313 98.0665 83.0079 33.4403 50.0835 46.8609 0.0119476 1.13124 6.55127 5.42003 1331196 1420454_at 11 B2 chr11:60005022-60005479 11 B2 UGA Mm.296366 19377 RP23-456O18.3 Rai1 Retinoic acid induced 1 (Rai1), transcript variant 1, mRNA cytoplasm;; metal ion binding;; negative regulation of multicellular organism growth;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; skeletal system development;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; negative regulation of biological process;; negative regulation of growth;; negative regulation of multicellular organismal process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process 1445.0073 1199.5999 1302.2075 152.7259 126.4229 104.8535 0.00035249969 3.37427 10.35731 6.98305 1331270 1420558_at 1 86.6 cM chr1:166079630-166080083 1 H2.2 chr1:166053831-166079876 1 H2.2 RSQ Mm.3337 NM_011347 1 1 20344 Selp selectin, platelet (Selp), mRNA. Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 119.1528 110.5827 109.1453 34.8972 52.1566 44.7254 0.01133157 1.38097 6.81859 5.43761 1331346 1420667_at 11 chr11:75582506-75583066 11 B5 chr11:75582591-75609559 11 B5 RSQ Mm.5137 NM_007873 1 1 13447 RP23-78H4.2 Doc2b double C2, beta (Doc2b), mRNA. calcium ion binding;; calcium-dependent phospholipid binding;; membrane;; synaptic vesicle;; transport;; transporter activity cell;; cell part;; organelle;; synapse;; synapse part cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle;; synapse part;; synaptic vesicle;; vesicle binding;; transporter activity ion binding;; lipid binding establishment of localization;; localization establishment of localization;; transport 853.7629 867.3510 745.1623 247.5408 417.4852 316.7284 0.017313093 1.35846 9.67986 8.32140 1344208 1420940_x_at 1 86.5 cM chr1:171620595-171622674 1 H3 chr1:171585631-171623657 1 H3 RSQ Mm.20954 NM_009063 1 1 19737 Rgs5 regulator of G-protein signaling 5 (Rgs5), mRNA. G-protein coupled receptor protein signaling pathway;; GTPase activator activity;; negative regulation of signal transduction;; signal transducer activity enzyme regulator activity;; molecular transducer activity enzyme activator activity;; nucleoside-triphosphatase regulator activity;; signal transducer activity biological regulation;; cellular process;; negative regulation of biological process;; regulation of biological process cell communication;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 572.7123 572.5171 659.2118 269.8551 299.0731 312.9852 0.00037900762 1.03236 9.22915 8.19678 1331586 1420985_at 3 chr3:88786292-88786833 3 F1 chr3:88769733-88883297 3 F1 RSQ Mm.130752 NM_138679 1 1 192195 Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) (Ash1l), mRNA. Lysine degradation;; Tight junction CLASS Metabolism; Amino Acid Metabolism; Lysine degradation [PATH:mmu00310] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] cell junction;; chromatin modification;; DNA binding;; histone-lysine N-methyltransferase activity;; metal ion binding;; methyltransferase activity;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; tight junction;; transcription;; transferase activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; protein binding;; transferase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 760.4818 719.8664 695.0346 200.7800 141.9667 190.8598 0.0039515575 2.04268 9.50110 7.45842 1331591 1420991_at 19 chr19:36187159-36191361 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 543.4858 572.1462 552.3462 150.5234 110.2621 120.1813 0.0031843136 2.14269 9.11859 6.97590 1331592 1420992_at 19 chr19:36186663-36186994 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 833.9297 840.3169 859.4762 216.4525 272.6037 271.8186 0.0035803102 1.74361 9.72196 7.97836 1344415 1421679_a_at 17 15.23 cM chr17:29235417-29235782 17 A3.3 chr17:29230716-29237667 17 A3.3 RSQ Mm.477981 NM_007669 2 1 12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA. ATM Signaling Pathway;; Cell Cycle: G1/S Check Point;; Cell Cycle: G2/M Checkpoint;; Cyclins and Cell Cycle Regulation;; Effects of calcineurin in Keratinocyte Differentiation;; Erythropoietin mediated neuroprotection through NF-kB;; Influence of Ras and Rho proteins on G1 to S Transition;; p53 Signaling Pathway Bladder cancer;; Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases;;; ErbB signaling pathway;; Glioma;; Melanoma;; p53 signaling pathway;; Pathways in cancer;; Prostate cancer cell cycle;; cell cycle arrest;; cyclin binding;; cyclin-dependent protein kinase holoenzyme complex;; cyclin-dependent protein kinase inhibitor activity;; cytoplasm;; cytosol;; kinase activity;; metal ion binding;; negative regulation of apoptosis;; negative regulation of cell proliferation;; negative regulation of cyclin-dependent protein kinase activity;; nucleus;; positive regulation of B cell proliferation;; positive regulation of programmed cell death;; protein binding;; protein kinase inhibitor activity;; regulation of cell cycle;; response to DNA damage stimulus;; response to UV;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; kinase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell cycle;; cell cycle process;; cell death;; cell proliferation;; cellular metabolic process;; leukocyte activation;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 357.3814 439.0449 478.9576 148.2599 136.7346 177.0608 0.0010027124 1.46266 8.72110 7.25844 1332209 1421854_at 5 A3|5 7.0 cM chr5:20882365-20882816 5 A3 UGA Mm.292100 14190 Fgl2 Fibrinogen-like protein 2, mRNA (cDNA clone MGC:19044 IMAGE:4189071) cytolysis;; extracellular region;; receptor binding;; signal transduction extracellular region binding protein binding biological regulation;; cellular process;; death;; regulation of biological process cell communication;; cell death;; regulation of biological process;; regulation of cellular process 288.2630 340.3263 413.0760 145.0481 117.3004 145.6007 0.0028392782 1.34399 8.42409 7.08011 1332210 1421855_at 5 A3|5 7.0 cM chr5:20883636-20884037 5 A3 UGA Mm.292100 14190 Fgl2 Fibrinogen-like protein 2, mRNA (cDNA clone MGC:19044 IMAGE:4189071) cytolysis;; extracellular region;; receptor binding;; signal transduction extracellular region binding protein binding biological regulation;; cellular process;; death;; regulation of biological process cell communication;; cell death;; regulation of biological process;; regulation of cellular process 595.4179 634.7235 637.9224 238.1206 366.8761 277.6180 0.023430798 1.10444 9.28166 8.17722 1344488 1421957_a_at 16 22.85 cM chr16:32471767-32471880 16 B3 chr16:32451788-32472101 16 B3 RSQ Mm.390903 NM_009981 1 1 13026 Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform (Pcyt1a), mRNA. Aminophosphonate metabolism;; Glycerophospholipid metabolism;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] Metabolism; Metabolism of Other Amino Acids; Aminophosphonate metabolism [PATH:mmu00440] biosynthetic process;; catalytic activity;; choline-phosphate cytidylyltransferase activity;; cytoplasm;; endoplasmic reticulum membrane;; glycogen granule;; membrane;; nucleotidyltransferase activity;; phosphatidylcholine biosynthetic process;; phosphatidylcholine biosynthetic process;; phospholipid biosynthetic process;; response to abiotic stimulus;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process;; response to stimulus alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; organophosphate metabolic process;; primary metabolic process;; response to abiotic stimulus 13242.8584 13524.8116 13585.2875 1232.6138 1610.5271 2823.0137 0.014164048 2.92072 13.71534 10.79461 1344655 1422557_s_at 8 45.0 cM chr8:96703191-96704176 8 C5 chr8:96702988-96704227 8 C5 RSQ Mm.192991 NM_013602 1 1 17748 Mt1 metallothionein 1 (Mt1), mRNA. cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 553.1219 564.5976 508.7587 257.6285 309.6789 236.8772 0.0058419446 1.02387 9.08112 8.05726 1332998 1422904_at 1 chr1:164806985-164807074 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 306.2734 322.8741 263.7075 94.9129 120.4577 98.4432 0.00048608452 1.51139 8.21210 6.70071 1344723 1422905_s_at 1 chr1:164806589-164806972 1 H2.1 chr1:164805177-164828843 1 H2.1 RSQ Mm.10929 NM_018881 1 1 55990 Fmo2 flavin containing monooxygenase 2 (Fmo2), mRNA. Drug metabolism - cytochrome P450 CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - cytochrome P450 [PATH:mmu00982] endoplasmic reticulum;; FAD binding;; flavin-containing monooxygenase activity;; integral to membrane;; intrinsic to endoplasmic reticulum membrane;; magnesium ion binding;; membrane;; microsome;; monooxygenase activity;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; oxygen and reactive oxygen species metabolic process cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; oxidation reduction 173.5499 137.0852 139.7368 71.1502 74.0252 69.9336 0.0080304917 1.05802 7.22157 6.16355 1333034 1422953_at 17 A3.2 chr17:18030321-18030898 17 A3.2 UG5 Mm.477887 14289 Fpr2 Formyl peptide receptor 2 (Fpr2), mRNA Neuroactive ligand-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 387.9877 388.7630 440.7630 164.4722 205.9289 227.5240 0.0084081061 1.03630 8.66216 7.62586 1333114 1423062_at 11 1.35 cM chr11:7106270-7106593 11 A1 chr11:7106088-7113926 11 A1 RSQ Mm.29254 NM_008343 1 1 16009 RP23-20C9.1 Igfbp3 insulin-like growth factor binding protein 3 (Igfbp3), mRNA. p53 signaling pathway CLASS Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] extracellular region;; extracellular space;; growth factor binding;; insulin-like growth factor binding;; negative regulation of cell proliferation;; negative regulation of protein amino acid phosphorylation;; nucleus;; osteoblast differentiation;; protein amino acid phosphorylation;; regulation of cell growth cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; cell growth;; cell proliferation;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; ossification;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process 4100.3396 4175.4638 4155.0795 844.5731 784.3094 934.8195 0.00092184005 2.28134 12.01664 9.73530 1333245 1423233_at 16 A2|16 9.0 cM chr16:15888053-15888517 16 A2 UGA Mm.347407 12609 Cebpd CCAAT/enhancer binding protein (C/EBP), delta (Cebpd), mRNA DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; promoter binding;; protein binding;; protein dimerization activity;; protein heterodimerization activity;; protein homodimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; specific RNA polymerase II transcription factor activity;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 545.2669 533.3518 631.0804 241.0987 325.1287 240.1790 0.0065942538 1.09504 9.15048 8.05544 1333522 1423559_at 7 23.5 cM chr7:53682916-53683489 7 B4 chr7:53651866-53694074 7 B4 RSQ Mm.249386 NM_001112739 2 1 16502 Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 (Kcnc1), transcript variant A, mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 636.1375 576.0434 589.0964 181.8186 230.5933 230.4479 0.0024167217 1.49391 9.22853 7.73462 1333550 1423597_at 5 chr5:68013016-68013563 5 C3.1 chr5:68009378-68238670 5 C3.1 RSQ Mm.153230 NM_009727 2 1 11980 Atp8a1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (Atp8a1), transcript variant 2, mRNA. ATP binding;; ATP biosynthetic process;; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;; catalytic activity;; cytoplasmic vesicle;; hydrolase activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; integral to membrane;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; nucleotide binding;; phospholipid transport;; phospholipid-translocating ATPase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; vesicle binding;; catalytic activity;; transporter activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; nitrogen compound metabolic process;; primary metabolic process;; transport 282.7674 237.6166 230.8396 99.6768 69.5696 93.7160 0.0029763435 1.52564 7.96224 6.43660 1333897 1424067_at 9 7.0 cM chr9:20832733-20833172 9 A3 chr9:20820403-20833241 9 A3 RSQ Mm.435508 NM_010493 1 1 15894 Icam1 intercellular adhesion molecule 1 (Icam1), mRNA. Adhesion Molecules on Lymphocyte;; B Lymphocyte Cell Surface Molecules;; CTL mediated immune response against target cells;; Monocyte and its Surface Molecules;; Neutrophil and Its Surface Molecules;; T Cytotoxic Cell Surface Molecules;; T Helper Cell Surface Molecules Cell adhesion molecules (CAMs);; Leukocyte transendothelial migration CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670];; Natural killer cell mediated cytotoxicity cell adhesion;; cell adhesion mediated by integrin;; cell-cell adhesion;; external side of plasma membrane;; immunological synapse;; integral to membrane;; leukocyte adhesion;; membrane;; protein binding;; regulation of cell adhesion;; T cell antigen processing and presentation cell;; cell part cell part;; cell surface;; membrane;; membrane part binding protein binding biological adhesion;; biological regulation;; cellular process;; immune system process;; regulation of biological process;; response to stimulus antigen processing and presentation;; cell adhesion;; immune effector process;; immune response;; regulation of biological process;; regulation of cellular process 32.7793 25.5397 27.9580 12.1927 14.3410 10.8553 0.001599296 1.20808 4.83819 3.63011 1334062 1424279_at 3 44.8 cM chr3:82835603-82836150 3 E3 chr3:82830074-82837549 3 E3 RSQ Mm.88793 NM_010196 2 1 14161 Fga fibrinogen alpha chain (Fga), transcript variant 2, mRNA. Complement and coagulation cascades CLASS Cellular Processes; Immune System; Complement and coagulation cascades [PATH:mmu04610] blood coagulation;; cell cortex cell;; cell part cell part;; intracellular;; intracellular part biological regulation;; multicellular organismal process;; response to stimulus coagulation;; regulation of biological quality;; regulation of body fluid levels;; response to external stimulus;; response to stress 1643.5945 1548.8396 1452.3215 623.4708 498.2980 630.0106 0.0017907538 1.41316 10.59459 9.18143 1334205 1424457_at 18 B2 chr18:36830844-36834637 18 B2 UG5 Mm.89673 225372 Apbb3 Amyloid beta (A4) precursor protein-binding, family B, member 3 (Apbb3), mRNA negative regulation of apoptosis;; protein binding binding protein binding biological regulation;; cellular process;; death;; developmental process;; negative regulation of biological process;; regulation of biological process cell death;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 570.5668 562.1031 536.0719 156.7904 205.8261 283.3828 0.028028062 1.41088 9.11908 7.70819 1334316 1424598_at 9 26.0 cM chr9:44444736-44445137 9 A5.2 chr9:44412974-44448814 9 A5.2 RSQ Mm.267061 NM_007841 3 1 13209 Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), transcript variant 3, mRNA. ATP binding;; ATP-dependent helicase activity;; cytoplasm;; helicase activity;; hydrolase activity;; nucleic acid binding;; nucleotide binding;; RNA binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity hydrolase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding 2001.0926 2172.4964 2221.5488 876.9485 916.9275 846.7059 4.7562173e-05 1.27544 11.05635 9.78091 1345101 1424607_a_at 3 chr3:42306621-42308720 3 B RSQ XR_030788 15 15 100039204 LOC100039204 PREDICTED: hypothetical protein LOC100039204 (LOC100039204), misc RNA. 2172.9304 2207.8772 2330.6435 916.8749 947.5559 941.3981 6.3276391e-05 1.25769 11.12679 9.86910 1345103 1424609_a_at IPA Mus musculus, Similar to RIKEN cDNA 1700066C05 gene, clone MGC:28125 IMAGE:3980327, mRNA, complete cds 1929.2824 1862.2814 1737.2725 471.4183 471.1816 642.1553 0.0038648608 1.81718 10.84644 9.02926 1334343 1424638_at 17 15.23 cM chr17:29237151-29237610 17 A3.3 chr17:29230716-29237667 17 A3.3 RSQ Mm.477981 NM_007669 2 1 12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA. ATM Signaling Pathway;; Cell Cycle: G1/S Check Point;; Cell Cycle: G2/M Checkpoint;; Cyclins and Cell Cycle Regulation;; Effects of calcineurin in Keratinocyte Differentiation;; Erythropoietin mediated neuroprotection through NF-kB;; Influence of Ras and Rho proteins on G1 to S Transition;; p53 Signaling Pathway Bladder cancer;; Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases;;; ErbB signaling pathway;; Glioma;; Melanoma;; p53 signaling pathway;; Pathways in cancer;; Prostate cancer cell cycle;; cell cycle arrest;; cyclin binding;; cyclin-dependent protein kinase holoenzyme complex;; cyclin-dependent protein kinase inhibitor activity;; cytoplasm;; cytosol;; kinase activity;; metal ion binding;; negative regulation of apoptosis;; negative regulation of cell proliferation;; negative regulation of cyclin-dependent protein kinase activity;; nucleus;; positive regulation of B cell proliferation;; positive regulation of programmed cell death;; protein binding;; protein kinase inhibitor activity;; regulation of cell cycle;; response to DNA damage stimulus;; response to UV;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; kinase regulator activity;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell cycle;; cell cycle process;; cell death;; cell proliferation;; cellular metabolic process;; leukocyte activation;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 2841.0170 2711.1166 2667.8203 897.4399 939.4244 931.2811 3.0573673e-06 1.56998 11.41944 9.84946 1334422 1424735_at 2 chr2:32270714-32271132 2 B chr2:32270006-32306939 2 B RSQ Mm.37395 NM_146118 1 1 227731 RP23-255P20.1 Slc25a25 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 (Slc25a25), nuclear gene encoding mitochondrial protein, mRNA. binding;; calcium ion binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding ion binding establishment of localization;; localization establishment of localization;; transport 147.7085 110.9898 147.2075 61.1878 68.9934 70.9562 0.0080073097 1.00339 7.06753 6.06414 1334625 1425014_at 6 chr6:92117449-92117773 6 D1 chr6:92089771-92117953 6 D1 RSQ Mm.87062 NM_011630 1 1 22026 Nr2c2 nuclear receptor subfamily 2, group C, member 2 (Nr2c2), mRNA. DNA binding;; ligand-dependent nuclear receptor activity;; metal ion binding;; nucleus;; receptor activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; spermatocyte division;; spermatogenesis;; spermatogenesis;; steroid hormone receptor activity;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; reproduction;; reproductive process biosynthetic process;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 120.2125 113.8210 120.0190 32.7201 35.2193 47.9810 0.0093261987 1.63080 6.88239 5.25160 1334673 1425079_at 8 chr8:72602280-72603860 8 B3.3 chr8:72596830-72603951 8 B3.3 RSQ Mm.37974 NM_181540 1 1 107770 Tm6sf2 transmembrane 6 superfamily member 2 (Tm6sf2), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 132.3589 129.2080 113.0168 56.4301 53.5581 50.3091 0.00030930319 1.22269 6.96075 5.73806 1334790 1425282_at 13 A5 chr13:47341178-47341731 13 A5 UG5 Mm.287609 218215 Rnf144b Ring finger protein 144B (Rnf144b), mRNA apoptosis;; integral to membrane;; ligase activity;; membrane;; metal ion binding;; modification-dependent protein catabolic process;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; death;; metabolic process catabolic process;; cell death;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 335.6677 292.6611 312.0848 143.3983 104.0944 151.3371 0.010989697 1.25417 8.28992 7.03575 1334803 1425303_at 11 1.0 cM chr11:5801000-5801377 11 A1 chr11:5800825-5849602 11 A1 RSQ Mm.220358 NM_010292 1 1 103988 RP23-340E18.1 Gck glucokinase (Gck), mRNA. Amino sugar and nucleotide sugar metabolism;; Glycolysis / Gluconeogenesis;; Insulin signaling pathway;; Maturity onset diabetes of the young CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Galactose metabolism [PATH:mmu00052] Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism [PATH:mmu00500] Metabolism; Carbohydrate Metabolism; Amino sugar and nucleotide sugar met;; Metabolic pathways;; Starch and sucrose metabolism;; Type II diabetes mellitus ATP binding;; carbohydrate metabolic process;; carbohydrate phosphorylation;; carbohydrate phosphorylation;; cellular glucose homeostasis;; glucokinase activity;; glucokinase activity;; glucose homeostasis;; glucose metabolic process;; glucose metabolic process;; glycolysis;; hexokinase activity;; kinase activity;; mitochondrion;; NADP metabolic process;; nucleotide binding;; phosphotransferase activity, alcohol group as acceptor;; positive regulation of insulin secretion;; protein binding;; regulation of insulin secretion;; regulation of potassium ion transport;; soluble fraction;; transferase activity cell;; cell part;; organelle cell fraction;; cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; catabolic process;; cell communication;; cellular homeostasis;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; generation of a signal involved in cell-cell signaling;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of localization;; secondary metabolic process;; secretion by cell;; transport 137.4896 157.6688 152.1246 50.6398 46.0774 42.7239 6.7202889e-05 1.68263 7.21768 5.53505 1334842 1425362_at 5 chr5:138104059-138104479 5 G2 chr5:138104037-138125921 5 G2 RSQ Mm.260869 NM_145566 1 1 231801 Agfg2 ArfGAP with FG repeats 2 (Agfg2), transcript variant 1, mRNA. ARF GTPase activator activity;; metal ion binding;; regulation of ARF GTPase activity;; zinc ion binding binding;; enzyme regulator activity enzyme activator activity;; ion binding;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 228.0360 239.1902 263.2127 70.7046 96.5410 117.7430 0.017051317 1.38631 7.92507 6.53877 1334929 1425514_at 13 50.0 cM chr13:102453666-102454171 13 D1 chr13:102450715-102462602 13 D1 RSQ Mm.259333 NM_001024955 2 1 18708 Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 1, mRNA. AKT Signaling Pathway;; B Cell Survival Pathway;; Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK);; Corticosteroids and cardioprotection;; CTCF: First Multivalent Nuclear Factor;; CXCR4 Signaling Pathway;; EGF Signaling Pathway;; Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia;; Fc Epsilon Receptor I Signaling in Mast Cells;; Growth Hormone Signaling Pathway;; Human Cytomegalovirus and Map Kinase Pathways;; IGF-1 Signaling Pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages;; Influence of Ras and Rho proteins on G1 to S Transition;; Inhibition of Cellular Proliferation by Gleevec;; Insulin Signaling Pathway;; mTOR Signaling Pathway;; Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation;; Nerve growth factor pathway (NGF);; NFAT and Hypertrophy of the heart (Transcription in the broken heart);; PDGF Signaling Pathway;; Phospholipase C Signaling Pathway;; Phospholipids as signalling intermediaries;; PTEN dependent cell cycle arrest and apoptosis;; Rac 1 cell motility signaling pathway;; Ras Signaling Pathway;; Ras-Independent pathway in NK cell-mediated cytotoxicity;; Regulation of BAD phosphorylation;; Regulation of eIF4e and p70 S6 Kinase;; Role of ERBB2 in Signal Transduction and Oncology;; Role of Erk5 in Neuronal Survival;; Role of nicotinic acetylcholine receptors in the regulation of apoptosis;; Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration;; Signaling of Hepatocyte Growth Factor Receptor;; Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway;; T Cell Receptor Signaling Pathway;; The Co-Stimulatory Signal During T-cell Activation;; The IGF-1 Receptor and Longevity;; Thrombin signaling and protease-activated receptors;; TPO Signaling Pathway;; Transcription factor CREB and its extracellular signals;; Trefoil Factors Initiate Mucosal Healing;; Trka Receptor Signaling Pathway;; Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Acute myeloid leukemia;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Colorectal cancer;; Endometrial cancer;; ErbB signaling pathway;; Fc epsilon RI signaling pathway;; Focal adhesion;; Glioma;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Leukocyte transendothelial migration;; Melanoma;; mTOR signaling pathway;; Natural killer cell mediated cytotoxicity;; Neurotrophin signaling pathway;; Non-small cell lung cancer CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; VEGF signaling pathway [PATH:mmu04370] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Informatio;; Pancreatic cancer;; Pathways in cancer;; Phosphatidylinositol signaling system;; Prostate cancer;; Regulation of actin cytoskeleton;; Renal cell carcinoma;; Small cell lung cancer;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway;; Type II diabetes mellitus;; VEGF signaling pathway 1-phosphatidylinositol-3-kinase activity;; B cell differentiation;; cytoplasm;; cytosol;; insulin receptor substrate binding;; intracellular;; kinase activity;; membrane;; negative regulation of apoptosis;; negative regulation of apoptosis;; negative regulation of cell-matrix adhesion;; negative regulation of osteoclast differentiation;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; positive regulation of cell migration;; protein amino acid phosphorylation;; protein binding;; signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; catalytic activity;; enzyme regulator activity kinase regulator activity;; protein binding;; transferase activity biological adhesion;; biological regulation;; cellular process;; death;; developmental process;; immune system process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; cell activation;; cell adhesion;; cell communication;; cell death;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; immune system development;; leukocyte activation;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of localization;; regulation of locomotion;; regulation of multicellular organismal process 9111.7046 8489.4064 8342.2805 3179.7718 1399.4852 2538.9511 0.030149324 1.94526 13.07706 11.13180 1334990 1425631_at 19 chr19:36807805-36808192 19 C2 chr19:36806220-36811094 19 C2 RSQ Mm.24724 NM_016854 1 1 53412 Ppp1r3c protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen biosynthetic process;; glycogen metabolic process;; protein binding;; protein targeting binding protein binding cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport 2245.2478 2252.6339 2327.4852 925.7221 950.2809 1215.3054 0.01052569 1.15362 11.15154 9.99792 1345554 1425837_a_at 3 chr3:51055003-51055460 3 C chr3:51028368-51055576 3 C RSQ Mm.86541 NM_009834 2 2 12457 Ccrn4l CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA. Selective expression of chemokine receptors during T-cell polarization rhythmic process rhythmic process 269.5804 235.2393 240.4633 109.2820 74.7242 79.8504 0.0066393343 1.51586 7.95408 6.43821 1335161 1425965_at 5 chr5:125866334-125870928 5 G1.1 RSQ XM_001479835 1 1 100048105 LOC100048105 PREDICTED: similar to Ubc protein, transcript variant 2 (LOC100048105), mRNA. PPAR signaling pathway CLASS Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] 8502.2497 8656.9348 8364.4378 2673.4290 4010.6292 3445.5307 0.015033004 1.35291 13.05444 11.70153 1335210 1426114_at IPA Unknown 3778.1128 3530.1850 3551.2695 1585.2491 1496.6111 1758.1376 0.00081166544 1.16843 11.82103 10.65260 1345786 1426235_a_at 1 chr1:155754454-155755308 1 G3 chr1:155747074-155756844 1 G3 RSQ Mm.210745 NM_008131 1 1 14645 Glul glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA. Alanine, aspartate and glutamate metabolism;; Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan biosynthesis [PATH:mmu0;; Nitrogen metabolism;; Peptidoglycan biosynthesis ATP binding;; catalytic activity;; cytoplasm;; glutamate-ammonia ligase activity;; glutamine biosynthetic process;; intracellular;; ligase activity;; mitochondrion;; nitrogen compound metabolic process;; nucleotide binding;; response to glucose stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to chemical stimulus 5886.7039 6323.4297 6344.3464 2352.4060 2770.9492 3390.2249 0.013823173 1.13925 12.59366 11.45442 1345787 1426236_a_at 1 chr1:155756223-155756784 1 G3 chr1:155747074-155756844 1 G3 RSQ Mm.210745 NM_008131 1 1 14645 Glul glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA. Alanine, aspartate and glutamate metabolism;; Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan biosynthesis [PATH:mmu0;; Nitrogen metabolism;; Peptidoglycan biosynthesis ATP binding;; catalytic activity;; cytoplasm;; glutamate-ammonia ligase activity;; glutamine biosynthetic process;; intracellular;; ligase activity;; mitochondrion;; nitrogen compound metabolic process;; nucleotide binding;; response to glucose stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to chemical stimulus 458.9332 339.1096 339.9714 105.0679 87.1669 117.0526 0.00067431979 1.87504 8.55234 6.67730 1335426 1426446_at 8 chr8:122686736-122687249 8 E1 chr8:122669128-122687318 8 E1 RSQ Mm.101958 NM_172286 1 1 234797 6430548M08Rik RIKEN cDNA 6430548M08 gene (6430548M08Rik), mRNA. 744.4696 678.4047 659.0964 372.1456 241.7120 331.1464 0.018449871 1.16074 9.43681 8.27606 1335676 1426808_at 14 chr14:47993534-48005842 14 C1 RSQ Mm.248615 NM_010705 2 1 16854 Lgals3 lectin, galactose binding, soluble 3 (Lgals3), transcript variant 2, mRNA. cell differentiation;; cytoplasm;; cytoplasm;; extracellular matrix organization;; IgE binding;; nucleus;; nucleus;; protein binding;; proteinaceous extracellular matrix;; skeletal system development;; sugar binding cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding carbohydrate binding;; protein binding cellular component organization;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; cellular developmental process;; extracellular structure organization;; multicellular organismal development 212.5964 191.2307 177.5100 76.3944 76.2112 67.1412 0.00017413956 1.40215 7.59430 6.19215 1335714 1426858_at 1 E2.3|1 64.1 cM chr1:121312137-121312619 1 E2.3 UGA Mm.3092 16324 Inhbb Inhibin beta-B subunit Cytokine-cytokine receptor interaction;; TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] extracellular region;; growth;; growth factor activity;; hormone activity;; negative regulation of insulin secretion extracellular region binding protein binding biological regulation;; cellular process;; establishment of localization;; growth;; localization;; negative regulation of biological process;; regulation of biological process cell communication;; cellular localization;; establishment of localization;; establishment of localization in cell;; generation of a signal involved in cell-cell signaling;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of transport;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of localization;; secretion by cell;; transport 1115.1781 998.9656 1049.8640 305.1468 213.5108 305.1533 0.0049893936 1.95947 10.04111 8.08164 1335858 1427035_at 14 chr14:70703392-70703860 14 D2 chr14:70703273-70748240 14 D2 RSQ Mm.270647 NM_001135152 3 1 213053 Slc39a14 solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 2, mRNA. ferrous iron transmembrane transporter activity;; integral to membrane;; ion transport;; iron ion transport;; membrane;; metal ion transmembrane transporter activity;; metal ion transport;; plasma membrane;; transport;; zinc ion binding;; zinc ion transmembrane transporter activity;; zinc ion transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 336.8695 369.3644 424.8182 161.1338 155.0082 260.9169 0.038567432 1.00663 8.55188 7.54525 1336133 1427384_at 2 H2 chr2:160772766-160773158 2 H2 UGA Mm.122738 71389 RP23-384K10.1 Chd6 Chromodomain helicase DNA binding protein 6, mRNA (cDNA clone IMAGE:3597702) helicase activity;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity 618.3342 576.8471 549.0709 142.4790 174.6236 175.0508 0.00051579363 1.83027 9.18171 7.35145 1336304 1427638_at 9 23.0 cM chr9:48462401-48644050 9 A5.3 RSQ Mm.457803 NM_001033324 1 1 235320 Zbtb16 zinc finger and BTB domain containing 16 (Zbtb16), mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer anterior/posterior pattern formation;; DNA binding;; embryonic hindlimb morphogenesis;; embryonic limb morphogenesis;; embryonic pattern specification;; forelimb morphogenesis;; leg morphogenesis;; male germ-line stem cell division;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of transcription, DNA-dependent;; nucleus;; nucleus;; positive regulation of apoptosis;; protein binding;; protein binding;; regulation of transcription;; skeletal system development;; specific transcriptional repressor activity;; transcriptional repressor complex;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription repressor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; sexual reproduction 512.3169 492.7017 476.1421 37.9391 43.5123 47.1655 0.00021176517 3.53069 8.94690 5.41621 1346214 1427747_a_at 2 27.0 cM chr2:32240946-32241323 2 B chr2:32240156-32243259 2 B RSQ Mm.9537 NM_008491 1 1 16819 RP23-161B9.11 Lcn2 lipocalin 2 (Lcn2), mRNA. binding;; extracellular region;; response to virus;; transport;; transporter activity extracellular region binding;; transporter activity establishment of localization;; localization;; multi-organism process;; response to stimulus establishment of localization;; response to biotic stimulus;; response to other organism;; transport 2660.7334 2529.7075 2582.3156 1127.0408 1179.7574 1101.9711 1.1270617e-05 1.18945 11.33894 10.14949 1346275 1427932_s_at 1 chr1:9226200-9228974 1 A2 RSQ XM_001472850 1 1 100039464 LOC100039464 PREDICTED: similar to gag protein, transcript variant 1 (LOC100039464), mRNA. 6563.1989 6610.9871 6908.7095 434.1351 562.1519 536.9156 0.00063106181 3.71989 12.70834 8.98846 1336689 1428306_at 10 chr10:59412481-59412957 10 B4 chr10:59412422-59414518 10 B4 RSQ Mm.21697 NM_029083 1 1 74747 Ddit4 DNA-damage-inducible transcript 4 (Ddit4), mRNA. mTOR signaling pathway CLASS Environmental Information Processing; Signal Transduction; mTOR signaling pathway [PATH:mmu04150] apoptosis;; cytoplasm;; negative regulation of signal transduction cell;; cell part cell part;; intracellular;; intracellular part biological regulation;; cellular process;; death;; negative regulation of biological process;; regulation of biological process cell communication;; cell death;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 910.6148 834.5841 807.8008 173.3186 241.4723 201.9950 0.0017892679 2.06076 9.73116 7.67039 1336820 1428776_at 5 E5 chr5:104034768-104035330 5 E5 UGA Mm.7446 75750 Slc10a6 Solute carrier family 10 (sodium/bile acid cotransporter family), member 6 (Slc10a6), mRNA bile acid:sodium symporter activity;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; symporter activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 17716.8011 17756.8861 17863.6954 1033.7424 1019.6752 2204.3208 0.0094789121 3.74666 14.11789 10.37122 1336865 1428942_at 8 45.0 cM chr8:96696756-96697386 8 C5 chr8:96696517-96697467 8 C5 RSQ Mm.147226 NM_008630 1 1 17750 Mt2 metallothionein 2 (Mt2), mRNA. cellular zinc ion homeostasis;; detoxification of copper ion;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 1491.9889 1412.7241 1337.1505 511.9971 506.2394 595.2630 0.00031770086 1.39706 10.46408 9.06702 1346626 1431213_a_at 8 UGA Mm.463370 Transcribed locus, weakly similar to XP_001379802.1 PREDICTED: similar to pol protein [Monodelphis domestica] 807.6354 838.6466 825.5298 306.3124 258.7374 350.0964 0.006862707 1.44428 9.68622 8.24194 1346830 1432273_a_at 1 94.0 cM chr1:175262194-175262805 1 H3 chr1:175262016-175263634 1 H3 RSQ Mm.6393 NM_010045 1 1 13349 Darc Duffy blood group, chemokine receptor (Darc), mRNA. G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; inflammatory response;; integral to membrane;; membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; regulation of biological process;; regulation of cellular process;; response to external stimulus;; response to stress 1981.9405 2251.3057 2196.3751 973.7976 1019.9236 1038.3640 0.00050573741 1.08278 11.06338 9.98061 1346897 1433428_x_at 2 H1|2 89.0 cM chr2:157942194-157942355 2 H1 UG5 Mm.330731 21817 RP23-396G1.2 Tgm2 Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943) Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 456.0433 436.7816 433.1717 182.9297 193.1415 198.7386 3.1018256e-05 1.20640 8.78753 7.58113 1337297 1433598_at 8 A1.1 chr8:8682359-8682883 8 A1.1 UGA Mm.251655 234023 Arglu1 RIKEN cDNA 9430010O03 gene, mRNA (cDNA clone IMAGE:4502890) 17254.9414 16859.1734 17458.6531 8536.0934 5068.4118 7885.3186 0.030527217 1.29866 14.06921 12.77054 1337327 1433691_at 19 chr19:36806257-36806814 19 C2 chr19:36806220-36811094 19 C2 RSQ Mm.24724 NM_016854 1 1 53412 Ppp1r3c protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen biosynthetic process;; glycogen metabolic process;; protein binding;; protein targeting binding protein binding cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport 306.5215 338.4297 312.7955 112.8214 179.4808 190.3074 0.046159554 1.02462 8.31721 7.29259 1346968 1433757_a_at 14 B chr14:31998914-31999067 14 B UG5 Mm.298728 64652 Nisch Imidazoline receptor I-1-like protein actin cytoskeleton organization;; apoptosis;; cell communication;; cytoplasm;; cytosol;; endosome;; integrin binding;; membrane;; negative regulation of cell migration;; phosphoinositide binding;; plasma membrane;; protein binding;; Rac protein signal transduction;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity lipid binding;; protein binding;; signal transducer activity biological regulation;; cellular component organization;; cellular process;; death;; localization;; locomotion;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cell death;; cell motility;; cell motion;; localization of cell;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion 250.7948 264.5927 244.0934 107.1790 122.1617 130.0901 0.002061891 1.08313 7.98309 6.89996 1337352 1433804_at 4 C6|4 46.3 cM chr4:100852069-100856981 4 C6 UGA Mm.289657 16451 RP23-336G7.2 Jak1 Janus kinase 1, mRNA (cDNA clone IMAGE:5148553) EGF Signaling Pathway;; IFN alpha signaling pathway;; IFN gamma signaling pathway;; IL 2 signaling pathway;; IL 4 signaling pathway;; IL 6 signaling pathway;; IL-10 Anti-inflammatory Signaling Pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; IL22 Soluble Receptor Signaling Pathway;; PDGF Signaling Pathway;; Stat3 Signaling Pathway Jak-STAT signaling pathway;; Pancreatic cancer CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Pancreatic cancer [PATH:mmu05212];; Pathways in cancer ATP binding;; cytokine-mediated signaling pathway;; cytoskeleton;; enzyme linked receptor protein signaling pathway;; Janus kinase activity;; kinase activity;; membrane;; non-membrane spanning protein tyrosine kinase activity;; nucleotide binding;; peptidyl-tyrosine phosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase cascade;; protein tyrosine kinase activity;; response to antibiotic;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; non-membrane-bounded organelle binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; response to chemical stimulus 1280.3741 1373.6406 1355.1301 466.1592 529.5078 521.1020 0.00019385867 1.40391 10.38345 8.97954 1347155 1435137_s_at IPA 1200015M12Rik RIKEN cDNA 1200015M12 gene 87.4274 71.4520 66.7127 28.0067 27.2285 23.6225 0.0009013986 1.51066 6.22294 4.71228 1337862 1435767_at 9 chr9:40098621-40099186 9 A5.1 chr9:40076800-40099203 9 A5.1 RSQ Mm.290083 NM_001083917 3 1 235281 Scn3b sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; sodium channel activity;; sodium ion binding;; sodium ion transport;; transport;; voltage-gated ion channel activity cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 197.9381 195.7433 179.4431 70.7070 86.9708 97.9104 0.0081424193 1.17649 7.57637 6.39988 1347265 1435944_s_at 2 73.9 cM chr2:131005398-131005598 2 F1 chr2:131003024-131005748 2 F1 RSQ Mm.440169 NM_007682 1 1 12616 RP23-32L15.4 Cenpb centromere protein B (Cenpb), mRNA. chromatin binding;; chromosome;; chromosome, centromeric region;; DNA binding;; nucleic acid binding;; nucleus;; regulation of transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1545.3383 1422.7902 1458.5964 853.8615 628.4143 732.7743 0.011103091 1.00931 10.52619 9.51689 1337902 1435950_at 14 chr14:70972823-70973293 14 D2 chr14:70953862-70973350 14 D2 RSQ Mm.7598 NM_021877 1 1 15460 Hr hairless (Hr), mRNA. DNA binding;; metal ion binding;; negative regulation of transcription;; nuclear body;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; zinc ion binding cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 2143.1672 2100.7630 2175.6269 509.3776 844.7421 1033.9999 0.039020624 1.48682 11.06315 9.57633 1347360 1436689_a_at 1 chr1:169298245-169298401 1 H2.3 chr1:169280121-169298661 1 H2.3 RSQ Mm.330055 NM_019993 1 1 56752 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA. 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation 4-trimethylammoniobutyraldehyde dehydrogenase activity;; aldehyde dehydrogenase (NAD) activity;; carnitine metabolic process;; cytoplasm;; cytosol;; metabolic process;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor cell;; cell part cell part;; intracellular;; intracellular part catalytic activity oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 1310.6035 1316.5267 1379.0798 488.0336 609.9845 605.4068 0.0052866466 1.24093 10.38268 9.14174 1338026 1436746_at 6 chr6:119919542-119940264 6 F1 chr6:119874355-119987797 6 F1 RSQ Mm.333349 NM_198703 1 1 232341 Wnk1 WNK lysine deficient protein kinase 1 (Wnk1), mRNA. ATP binding;; cytoplasm;; ion transport;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase inhibitor activity;; protein serine/threonine kinase activity;; regulation of cellular process;; soluble fraction;; transferase activity;; vesicular fraction cell;; cell part cell fraction;; cell part;; intracellular;; intracellular part binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; kinase regulator activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; regulation of biological process cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; transport 1217.1969 1431.3901 1500.7992 504.1524 766.2506 725.0438 0.015970686 1.07425 10.42802 9.35377 1338029 1436766_at 6 B1 chr6:38518985-38519541 6 B1 UGA Mm.276133 192196 Luc7l2 LUC7-like 2 (S. cerevisiae) (Luc7l2), mRNA metal ion binding;; protein binding;; zinc ion binding binding ion binding;; protein binding 803.9646 840.0469 819.2061 293.6618 338.6343 350.7931 0.0022953189 1.32911 9.68113 8.35202 1338059 1436898_at 4 D2.2|4 57.6 cM chr4:126704853-126705318 4 D2.2 UG5 Mm.257276 71514 RP23-153M14.2 Sfpq Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) (Sfpq), mRNA RNA polymerase III transcription DNA binding;; DNA repair;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; RNA binding;; RNA splicing;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to stress 342.9125 324.4821 312.8969 136.1223 199.1023 151.5819 0.019787268 1.02772 8.35108 7.32336 1338064 1436910_at 1 chr1:159106227-159122987 1 H1 chr1:159065313-159342726 1 H1 RSQ Mm.235028 NM_177644 1 1 226525 Rasal2 RAS protein activator like 2 (Rasal2), mRNA. 2893.0563 3037.0839 3145.3310 1432.7946 1410.8004 1477.9568 8.0315742e-05 1.06985 11.56195 10.49210 1347528 1437277_x_at 2 H1|2 89.0 cM chr2:157942194-157942355 2 H1 UGA Mm.330731 21817 RP23-396G1.2 Tgm2 Transglutaminase 2, C polypeptide, mRNA (cDNA clone MGC:6152 IMAGE:3256943) Phospholipase C d1 in phospholipid associated cell signaling Huntington's disease CLASS Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; acyltransferase activity;; branching involved in salivary gland morphogenesis;; calcium ion binding;; cytoplasm;; cytosol;; G-protein coupled receptor protein signaling pathway;; GTP binding;; membrane;; metal ion binding;; peptide cross-linking;; positive regulation of cell adhesion;; protein-glutamine gamma-glutamyltransferase activity;; proteinaceous extracellular matrix;; salivary gland cavitation;; transferase activity cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; nucleotide binding;; transferase activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 1031.1579 993.4510 956.7375 307.5396 393.4332 504.3200 0.020989385 1.33518 9.95611 8.62093 1347565 1437398_a_at 1 chr1:169297696-169298074 1 H2.3 chr1:169280121-169298661 1 H2.3 RSQ Mm.330055 NM_019993 1 1 56752 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA. 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation 4-trimethylammoniobutyraldehyde dehydrogenase activity;; aldehyde dehydrogenase (NAD) activity;; carnitine metabolic process;; cytoplasm;; cytosol;; metabolic process;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor cell;; cell part cell part;; intracellular;; intracellular part catalytic activity oxidoreductase activity cellular process;; metabolic process cellular metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 183.2404 167.9852 157.0864 64.8900 79.2127 92.4365 0.0083057662 1.11574 7.40173 6.28599 1347732 1438069_a_at 9 F1 chr9:107662113-107662156 9 F1 UGA Mm.259197 83486 Rbm5 RNA binding motif protein 5 (Rbm5), mRNA apoptosis;; intracellular;; metal ion binding;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus;; RNA binding;; RNA splicing;; spliceosomal complex;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding ion binding;; nucleic acid binding;; nucleotide binding cellular process;; death;; metabolic process cell death;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 2031.9928 2318.7218 2400.7840 1078.7013 969.4890 1326.1633 0.0061183365 1.00929 11.13236 10.12307 1347820 1438385_s_at 8 C3 chr8:88051301-88051346 8 C3 UGA Mm.200423 108682 Gpt2 Glutamic pyruvate transaminase (alanine aminotransferase) 2, mRNA (cDNA clone MGC:37704 IMAGE:5065322) Alanine, aspartate and glutamate metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate metabolism [PATH:mmu00250] biosynthetic process;; catalytic activity;; L-alanine:2-oxoglutarate aminotransferase activity;; pyridoxal phosphate binding;; transaminase activity;; transferase activity;; transferase activity, transferring nitrogenous groups binding;; catalytic activity cofactor binding;; lipid binding;; transferase activity;; vitamin binding metabolic process biosynthetic process 592.2986 656.2075 604.3084 230.0212 396.5964 263.6886 0.039251809 1.09583 9.26911 8.17328 1338326 1438677_at 2 chr2:59160639-59176922 2 C1.1 chr2:58998906-59193262 2 C1.1 RSQ Mm.260938 NM_026361 2 1 227937 RP23-311G5.1 Pkp4 plakophilin 4 (Pkp4), transcript variant 1, mRNA. binding;; cell adhesion;; cell junction;; protein binding cell;; cell part cell part;; membrane;; membrane part binding protein binding biological adhesion;; cellular process cell adhesion 376.0464 358.0357 365.3756 132.6213 118.5343 121.8748 0.00018622819 1.56079 8.51732 6.95653 1338349 1438758_at 12 A1.3 IPA AL024210 expressed sequence AL024210 69.9458 56.3407 64.5691 25.7117 31.1987 30.7198 0.00092519286 1.12273 5.98568 4.86295 1338358 1438824_at 2 chr2:129026331-129026905 2 F1 UG5 Mm.406240 Transcribed locus 36.4440 45.2134 49.9336 18.2036 22.5640 23.2114 0.0044464023 1.03646 5.44274 4.40629 1338466 1441115_at 18 9.0 cM chr18:21125726-21126191 18 A2 IPA D18Ertd232e DNA segment, Chr 18, ERATO Doi 232, expressed 2246.7210 2309.7543 2459.0726 664.2395 916.7352 1259.6637 0.034423058 1.35209 11.19034 9.83825 1348119 1442025_a_at 9 chr9:48459944-48460104 9 A5.3 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 490.9788 532.1944 522.0408 129.7918 232.6942 258.2096 0.045245902 1.37620 9.00778 7.63158 1338484 1442026_at 9 chr9:48460144-48460494 9 A5.3 UGA Mm.34106 Transcribed locus, strongly similar to NP_001028496.1 zinc finger and BTB domain containing 16 [Mus musculus] 90.6927 94.4416 85.5279 55.9900 40.0732 37.1881 0.024146741 1.04472 6.49420 5.44948 1338495 1442494_at 17 C chr17:47145036-47145543 17 C UGA Mm.28234 224826 Ubr2 Ubiquitin protein ligase E3 component n-recognin 2 (Ubr2), mRNA ligase activity;; male meiosis I;; metal ion binding;; modification-dependent protein catabolic process;; nucleus;; protein binding;; protein binding;; protein catabolic process;; spermatogenesis;; ubiquitin ligase complex;; ubiquitin-dependent protein catabolic process;; ubiquitin-protein ligase activity;; ubiquitin-protein ligase activity;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; metabolic process;; reproduction;; reproductive process catabolic process;; cell cycle;; cell cycle process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; primary metabolic process;; reproductive process;; sexual reproduction 2694.9050 2752.8130 2685.5082 816.3741 930.9440 1011.2987 0.0029139713 1.56535 11.40456 9.83921 1338746 1448181_at 6 chr6:90424643-90425023 6 D1 chr6:90412619-90425203 6 D1 RSQ Mm.41389 NM_023184 1 1 66277 Klf15 Kruppel-like factor 15 (Klf15), mRNA. DNA binding;; DNA binding;; glucose transport;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; positive regulation of transcription, DNA-dependent;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 1299.7133 1151.9785 1182.8317 433.5647 256.8741 460.7716 0.020504634 1.70299 10.24063 8.53764 1338782 1448231_at 17 13.0 cM chr17:28537316-28537865 17 A3.3 chr17:28536039-28623057 17 A3.3 RSQ Mm.276405 NM_010220 1 1 14229 Fkbp5 FK506 binding protein 5 (Fkbp5), mRNA. binding;; cytoplasm;; isomerase activity;; nucleus;; peptidyl-prolyl cis-trans isomerase activity;; protein binding;; protein folding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 2244.7663 2353.4620 2388.8081 846.8803 1124.3838 870.4777 0.0076767855 1.30947 11.18500 9.87553 1338839 1448306_at 12 chr12:56590943-56592243 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 126.2640 107.7231 117.4833 35.0984 23.1433 29.4871 0.0032781967 2.01998 6.86927 4.84929 1339138 1448680_at 12 51.0 cM chr12:105133323-105135281 12 E chr12:105133135-105143160 12 E RSQ Mm.439694 NM_009245 2 2 20702 Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C (Serpina1c), mRNA. endopeptidase inhibitor activity;; extracellular region;; protein amino acid N-linked glycosylation;; protein binding;; response to cytokine stimulus;; response to peptide hormone stimulus;; serine-type endopeptidase inhibitor activity extracellular region binding;; enzyme regulator activity enzyme inhibitor activity;; protein binding cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; response to chemical stimulus;; response to endogenous stimulus 239.4045 208.0408 203.0835 111.1766 87.2698 88.9997 0.0017112852 1.18337 7.75665 6.57328 1339148 1448690_at 8 chr8:128554040-128554462 8 E2 chr8:128519001-128554585 8 E2 RSQ Mm.10800 NM_008430 1 1 16525 Kcnk1 potassium channel, subfamily K, member 1 (Kcnk1), mRNA. endosome;; integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 520.9595 485.6992 463.8577 51.9469 40.4398 56.9565 0.00080028763 3.31268 8.93550 5.62282 1339204 1448756_at 3 43.6 cM chr3:90496586-90499210 3 F1 chr3:90496554-90499613 3 F1 RSQ Mm.2128 NM_009114 1 1 20202 S100a9 S100 calcium binding protein A9 (calgranulin B) (S100a9), mRNA. actin cytoskeleton reorganization;; calcium ion binding;; leukocyte chemotaxis;; regulation of integrin biosynthetic process binding ion binding biological regulation;; cellular component organization;; cellular process;; immune system process;; localization;; locomotion;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; behavior;; biosynthetic process;; cell motility;; cell motion;; cellular response to stimulus;; leukocyte migration;; localization of cell;; macromolecule metabolic process;; membrane organization;; organelle organization;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to external stimulus;; taxis 520.1263 498.0964 518.7075 183.5635 252.7038 222.4415 0.010280341 1.23435 9.00059 7.76624 1339365 1448949_at 11 chr11:84778223-84778345 11 C chr11:84771255-84779556 11 C RSQ Mm.1641 NM_007607 1 1 12351 RP23-167D6.1 Car4 carbonic anhydrase 4 (Car4), mRNA. Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] anchored to membrane;; carbonate dehydratase activity;; lyase activity;; membrane;; metal ion binding;; one-carbon metabolic process;; plasma membrane;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 1379.4770 1237.2908 1228.5944 406.0670 661.6726 659.9662 0.031330808 1.18796 10.32189 9.13393 1339476 1449089_at 16 chr16:76291166-76291540 16 C3.1 chr16:76291106-76373294 16 C3.1 RSQ Mm.455873 NM_173440 1 1 268903 Nrip1 nuclear receptor interacting protein 1 (Nrip1), mRNA. histone deacetylase binding;; histone deacetylase complex;; lipid storage;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; ovarian follicle rupture;; ovulation;; protein binding;; receptor activity;; receptor binding;; regulation of transcription, DNA-dependent;; retinoid X receptor binding;; transcription;; transcription corepressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity protein binding;; signal transducer activity;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; biosynthetic process;; cellular metabolic process;; gamete generation;; macromolecule localization;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 297.7171 290.5964 278.9897 71.9942 92.7803 91.8073 0.0031577665 1.76622 8.17491 6.40870 1339662 1449311_at 16 C3.3 chr16:87730397-87730943 16 C3.3 UGA Mm.26147 12013 Bach1 BTB and CNC homology 1 (Bach1), mRNA DNA binding;; nucleus;; protein binding;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 173.8290 157.6806 175.1296 57.6538 42.2921 51.3343 0.0023094496 1.75372 7.39822 5.64450 1339699 1449360_at 15 43.3 cM chr15:78112991-78113449 15 E1 chr15:78112939-78128810 15 E1 RSQ Mm.1940 NM_007781 1 1 12984 Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) (Csf2rb2), mRNA. Regulation of BAD phosphorylation Apoptosis;; Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] cytokine receptor activity;; cytokine-mediated signaling pathway;; integral to membrane;; membrane;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 102.0069 86.8801 74.4123 43.2876 39.1803 43.6310 0.0082822371 1.05191 6.44365 5.39174 1339804 1449484_at 11 chr11:31259509-31260000 11 A4 chr11:31259440-31270061 11 A4 RSQ Mm.32506 NM_011491 1 1 20856 Stc2 stanniocalcin 2 (Stc2), mRNA. extracellular region;; hormone activity extracellular region binding protein binding 700.1195 685.0384 707.7250 300.1185 337.7652 297.3741 0.0016539716 1.16438 9.44618 8.28180 1339832 1449519_at 6 chr6:66985453-66985671 6 C1 chr6:66985089-66987401 6 C1 RSQ Mm.389750 NM_007836 1 1 13197 Gadd45a growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), mRNA. ATM Signaling Pathway;; Cell Cycle: G2/M Checkpoint;; p53 Signaling Pathway Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] cell cycle;; cell cycle arrest;; centrosome cycle;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cellular metabolic process;; microtubule-based process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function;; response to stress 393.3762 400.2617 420.8046 59.3971 91.1739 62.6944 0.0050188311 2.53615 8.66052 6.12438 1348421 1449526_a_at 7 chr7:133911136-133919078 7 F3 chr7:133909927-133919159 7 F3 RSQ Mm.246881 NM_024228 1 1 68616 Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 (Gdpd3), mRNA. glycerol metabolic process;; glycerophosphodiester phosphodiesterase activity;; hydrolase activity;; integral to membrane;; lipid metabolic process;; membrane;; phosphoric diester hydrolase activity cell;; cell part cell part;; membrane;; membrane part catalytic activity hydrolase activity cellular process;; metabolic process alcohol metabolic process;; cellular metabolic process;; primary metabolic process 311.8064 219.6831 224.5103 108.7865 89.2876 119.3750 0.0046854888 1.24311 7.95814 6.71503 1348434 1449590_a_at 9 chr9:99288490-99290204 9 E3.3 chr9:99285838-99337131 9 E3.3 RSQ Mm.2045 NM_008624 1 1 17532 Mras muscle and microspikes RAS (Mras), mRNA. MAPK signaling pathway;; Regulation of actin cytoskeleton CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530];; Tight junction GTP binding;; intracellular;; membrane;; nucleotide binding;; plasma membrane;; small GTPase mediated signal transduction cell;; cell part cell part;; intracellular;; membrane binding nucleotide binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 1586.9702 1638.8643 1640.1318 506.1519 872.1783 751.7369 0.034018312 1.22805 10.66338 9.43533 1348480 1449731_s_at 12 chr12:56590515-56590785 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 1117.3245 1064.5933 1099.8317 359.0207 641.8855 452.1519 0.037026237 1.21674 10.09500 8.87825 1348488 1449773_s_at 10 60.5 cM chr10:80394702-80394906 10 C1 chr10:80392835-80394949 10 C1 RSQ Mm.1360 NM_008655 1 1 17873 Gadd45b growth arrest and DNA-damage-inducible 45 beta (Gadd45b), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 457.2630 478.9297 437.1947 86.9434 103.0473 130.2286 0.0045707662 2.11954 8.83756 6.71802 1348516 1449901_a_at 4 chr4:132807657-132808759 4 D2.3 chr4:132796732-132808843 4 D2.3 RSQ Mm.36640 NM_016693 1 1 53608 Map3k6 mitogen-activated protein kinase kinase kinase 6 (Map3k6), mRNA. MAPKinase Signaling Pathway MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] ATP binding;; kinase activity;; magnesium ion binding;; MAP kinase kinase kinase activity;; metal ion binding;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity;; molecular transducer activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 190.2294 187.8696 192.3820 43.9804 39.6582 39.0756 0.00040041191 2.21883 7.57101 5.35218 1340074 1449906_at 1 86.6 cM chr1:166074030-166079220 1 H2.2 chr1:166053831-166079876 1 H2.2 RSQ Mm.3337 NM_011347 1 1 20344 Selp selectin, platelet (Selp), mRNA. Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 2205.4019 2228.7374 2285.5771 1021.8277 1266.4219 1060.7164 0.0075914074 1.01096 11.12906 10.11810 1348544 1449999_a_at 5 4.0 cM chr5:15871609-15876712 5 A2 chr5:15440508-15880329 5 A2 RSQ Mm.159842 NM_001110846 5 1 12293 Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 (Cacna2d1), transcript variant d, mRNA. Cardiac muscle contraction CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Circulatory System; Cardiac muscle contraction [PATH:mmu04260];; MAPK signaling pathway calcium channel activity;; calcium ion binding;; calcium ion transport;; integral to membrane;; ion channel activity;; ion transport;; membrane;; metal ion binding;; protein binding;; regulation of calcium ion transport;; sarcoplasmic reticulum;; T-tubule;; transport;; voltage-gated ion channel activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity biological regulation;; establishment of localization;; localization;; regulation of biological process establishment of localization;; regulation of biological process;; regulation of localization;; transport 162.2112 160.7909 154.1230 58.6620 100.5462 84.0968 0.046685712 1.00622 7.31290 6.30668 1340176 1450051_at X 43.8 cM chrX:103072336-103072892 X D chrX:102992953-103124711 X D RSQ Mm.475674 NM_009530 1 1 22589 RP23-170G19.5 Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) (Atrx), mRNA. ATP binding;; chromatin binding;; DNA binding;; DNA repair;; forebrain development;; helicase activity;; heterochromatin;; hydrolase activity;; metal ion binding;; nuclear chromosome;; nucleic acid binding;; nucleotide binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; sequence-specific DNA binding;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; catalytic activity;; transcription regulator activity chromatin binding;; hydrolase activity;; ion binding;; nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to stress 478.6041 582.4354 535.5104 84.4673 87.3341 90.5160 0.00030426982 2.60151 9.05114 6.44963 1340562 1450606_at 11 chr11:98248718-98249320 11 D chr11:98247945-98249411 11 D RSQ Mm.57030 NM_008890 1 1 18948 RP23-355L10.6 Pnmt phenylethanolamine-N-methyltransferase (Pnmt), mRNA. Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Tyrosine metabolism [PATH:mmu00350];; Tyrosine metabolism catecholamine biosynthetic process;; methyltransferase activity;; phenylethanolamine N-methyltransferase activity;; transferase activity catalytic activity transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process 169.9170 134.2865 142.9125 44.4488 49.8159 58.1478 0.00053463894 1.55420 7.21228 5.65809 1340700 1450783_at 19 chr19:34724141-34724445 19 C1 chr19:34715378-34724499 19 C1 RSQ Mm.439751 NM_008331 1 1 15957 Ifit1 interferon-induced protein with tetratricopeptide repeats 1 (Ifit1), mRNA. binding binding 1520.4009 1442.3760 1584.7733 606.4323 949.1765 699.3951 0.028031115 1.03661 10.56484 9.52823 1340845 1450971_at 10 60.5 cM chr10:80393047-80394413 10 C1 chr10:80392835-80394949 10 C1 RSQ Mm.1360 NM_008655 1 1 17873 Gadd45b growth arrest and DNA-damage-inducible 45 beta (Gadd45b), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 389.9536 403.0334 363.1381 185.4493 172.5555 173.0195 5.9473468e-05 1.12190 8.58876 7.46686 1341107 1451340_at 1 chr1:36376801-36377288 1 B chr1:36364598-36379820 1 B RSQ Mm.34316 NM_145996 1 1 214855 Arid5a AT rich interactive domain 5A (MRF1-like) (Arid5a), mRNA. DNA binding;; intracellular;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 820.1534 830.6028 739.7736 174.3572 222.4297 163.2715 0.0015001959 2.10482 9.63623 7.53141 1341119 1451355_at 4 chr4:86566201-86566728 4 C4 chr4:86520367-86566779 4 C4 RSQ Mm.45019 NM_139306 1 1 230379 RP24-468M3.3 Acer2 alkaline ceramidase 2 (Acer2), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramidase activity;; ceramide metabolic process;; endoplasmic reticulum membrane;; Golgi apparatus;; Golgi membrane;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;; integral to membrane;; lipid metabolic process;; membrane cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity hydrolase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 356.0557 313.3589 358.7005 141.6896 136.2515 115.1924 0.00046136605 1.38988 8.41809 7.02821 1341279 1451569_at 6 D1 chr6:92118495-92118956 6 D1 UGA Mm.87062 22026 Nr2c2 CD-1 orphan receptor TAK1 (TAK1) DNA binding;; ligand-dependent nuclear receptor activity;; metal ion binding;; nucleus;; receptor activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; spermatocyte division;; spermatogenesis;; spermatogenesis;; steroid hormone receptor activity;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; reproduction;; reproductive process biosynthetic process;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 1373.3654 1300.9696 1326.1430 429.0317 660.0155 638.8233 0.023865388 1.23711 10.38063 9.14352 1341282 1451577_at 16 B4|16 28.9 cM chr16:43619340-43619721 16 B4 UGA Mm.440824 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 200.9062 245.3227 241.3579 51.8993 43.7403 53.0672 6.6556603e-05 2.20855 7.83465 5.62609 1341305 1451612_at 8 C5|8 45.0 cM chr8:96703143-96703979 8 C5 UGA Mm.192991 17748 Mt1 Metallothionein 1, mRNA (cDNA clone MGC:47147 IMAGE:4990006) cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 1629.9509 1790.5964 1860.1253 229.7631 276.4024 442.2075 0.0098434424 2.53160 10.77934 8.24774 1341364 1451715_at 2 91.0 cM chr2:160191130-160191719 2 H2 chr2:160189412-160192801 2 H2 RSQ Mm.330745 NM_010658 1 1 16658 RP23-333A18.1 Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA. brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 2766.2138 2808.5714 2755.7235 652.5212 666.6209 1120.3174 0.018992584 1.81908 11.43918 9.62010 1341365 1451716_at 2 H2|2 91.0 cM chr2:160189869-160190403 2 H2 UG5 Mm.330745 16658 RP23-333A18.1 Mafb V-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 1517.9565 1522.1784 1300.0986 478.7051 504.2193 452.6938 0.00021414882 1.59365 10.49475 8.90110 1341390 1451756_at 5 G|5 82.0 cM chr5:148449686-148450062 5 G3 UGA Mm.389712 14254 Flt1 FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) Cytokine-cytokine receptor interaction;; Endocytosis;; Focal adhesion CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] angiogenesis;; ATP binding;; cell differentiation;; cell migration;; identical protein binding;; integral to membrane;; kinase activity;; membrane;; multicellular organismal development;; nucleotide binding;; patterning of blood vessels;; protein amino acid phosphorylation;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway;; vascular endothelial growth factor receptor activity;; vascular endothelial growth factor receptor signaling pathway;; vascular endothelial growth factor receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 197.3820 258.9297 255.3610 112.4359 103.9248 75.5867 0.0052224891 1.29508 7.87922 6.58414 1341465 1451883_at 3 A2|3 chr3:19586092-19586509 3 A2 UGA Mm.450006 620316 BC002189 CDNA sequence BC002189, mRNA (cDNA clone MGC:7386 IMAGE:3487872) 318.8186 289.6106 287.8437 157.1592 124.7498 155.3500 0.0043200835 1.04178 8.22123 7.17945 1341577 1452082_at 8 E1 chr8:122685928-122686463 8 E1 UGA Mm.101958 234797 6430548M08Rik RIKEN cDNA 6430548M08 gene, mRNA (cDNA clone MGC:38801 IMAGE:5359842) 489.4047 411.5800 436.7554 186.2721 178.5379 182.5308 0.0020784944 1.28575 8.79686 7.51112 1341738 1452282_at 8 chr8:75018537-75019040 8 B3.3 chr8:75018459-75072169 8 B3.3 RSQ Mm.235885 NM_027485 1 1 70625 Med26 mediator complex subunit 26 (Med26), mRNA. DNA binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 738.8005 994.1236 922.4468 380.7794 382.8844 528.7865 0.0074141306 1.04518 9.77855 8.73337 1349242 1452349_x_at 1 chr1:175826485-175843053 1 H3 RSQ Mm.476726 NM_001033450 2 2 381308 Mnda myeloid cell nuclear differentiation antigen (Mnda), mRNA. 416.6645 432.9441 433.9074 185.7766 225.8013 219.1797 0.0053645892 1.02991 8.74067 7.71077 1341817 1452378_at 19A chr19:5800663-5801120 19 A chr19:5795689-5802671 19 A RSQ NR_002847 1 1 72289 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA. 2454.4382 2474.0116 2276.4843 468.7530 571.9240 580.5158 0.00065088281 2.15762 11.22880 9.07119 1341848 1452418_at 1 chr1:9226200-9228974 1 A2 RSQ XM_001472850 5 3 100039464 LOC100039464 PREDICTED: similar to gag protein, transcript variant 1 (LOC100039464), mRNA. 1369.7070 1305.6663 1303.6650 465.7838 354.1816 540.6219 0.011646682 1.56941 10.37286 8.80345 1349296 1452519_a_at 7 10.2 cM chr7:29161986-29162456 7 A3 chr7:29161802-29164247 7 A3 RSQ Mm.389856 NM_011756 1 1 22695 Zfp36 zinc finger protein 36 (Zfp36), mRNA. AU-rich element binding;; cytoplasm;; cytosol;; cytosol;; DNA binding;; metal ion binding;; mRNA binding;; mRNA binding;; mRNA catabolic process;; negative regulation of inflammatory response;; negative regulation of myeloid cell differentiation;; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;; nuclear-transcribed mRNA poly(A) tail shortening;; nucleic acid binding;; nucleus;; protein kinase cascade;; regulation of mRNA stability;; RNA destabilization;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of response to stimulus;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; response to external stimulus;; response to stress 2186.3064 1989.7729 1988.7766 493.3344 888.6739 780.3327 0.023550517 1.55349 11.00344 9.44996 1349404 1453238_s_at 11 chr11:86626266-86629631 11 C RSQ NR_002860 11 10 319269 A130040M12Rik RIKEN cDNA A130040M12 gene (A130040M12Rik), non-coding RNA. 3062.8135 3181.6947 3208.7820 1634.7309 1067.5408 898.5303 0.029668043 1.43923 11.62134 10.18211 1349481 1453851_a_at 13 chr13:51943246-51943781 13 A5 chr13:51942063-51943844 13 A5 RSQ Mm.281298 NM_011817 1 1 23882 Gadd45g growth arrest and DNA-damage-inducible 45 gamma (Gadd45g), mRNA. Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] activation of MAPKK activity;; apoptosis;; cell differentiation;; interferon-gamma biosynthetic process;; multicellular organismal development;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; T-helper 1 cell differentiation cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; cytokine production;; immune response;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 290.9886 255.9993 290.4121 112.4853 91.4219 118.8125 0.0016795469 1.38206 8.12226 6.74020 1342222 1454030_at 19 A chr19:3477831-3478364 19 A UGA Mm.284686 52036 Saps3 SAPS domain family, member 3 (Saps3), mRNA cytoplasm;; nucleus;; protein phosphatase binding;; regulation of phosphoprotein phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cellular metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 326.4548 328.7063 317.1519 111.0687 135.9329 103.2924 0.0056410582 1.48259 8.34014 6.85755 1349517 1454037_a_at 5 82.0 cM chr5:148466686-148485183 5 G3 chr5:148373771-148537564 5 G3 RSQ Mm.389712 NM_010228 1 1 14254 Flt1 FMS-like tyrosine kinase 1 (Flt1), mRNA. Cytokine-cytokine receptor interaction;; Endocytosis;; Focal adhesion CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] angiogenesis;; ATP binding;; cell differentiation;; cell migration;; identical protein binding;; integral to membrane;; kinase activity;; membrane;; multicellular organismal development;; nucleotide binding;; patterning of blood vessels;; protein amino acid phosphorylation;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway;; vascular endothelial growth factor receptor activity;; vascular endothelial growth factor receptor signaling pathway;; vascular endothelial growth factor receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cellular developmental process;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 57.4732 44.0718 41.3349 16.1563 16.7283 11.7841 0.0015582676 1.67962 5.55863 3.87901 1349572 1454608_x_at 18 7.0 cM chr18:20832268-20832377 18 A2 chr18:20823913-20832820 18 A2 RSQ Mm.2108 NM_013697 1 1 22139 Ttr transthyretin (Ttr), mRNA. extracellular region;; hormone activity;; thyroid hormone generation;; transport extracellular region binding protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; hormone metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological quality;; transport 901.7931 860.0940 908.3186 402.0770 429.9424 435.5353 4.1467783e-05 1.07536 9.79735 8.72199 1342410 1455220_at 19 37.6 cM chr19:41920549-41921065 19 C3 chr19:41920467-41922622 19 C3 RSQ Mm.222723 NM_177603 1 1 212398 Frat2 frequently rearranged in advanced T-cell lymphomas 2 (Frat2), mRNA. Wnt signaling pathway CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Wnt receptor signaling pathway;; Wnt receptor signaling pathway biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 1664.2896 1416.2154 1466.3313 469.9297 420.6888 500.4297 7.4421022e-05 1.70886 10.56217 8.85331 1342536 1455869_at 11 chr11:5908951-5909394 11 A1 UGA Mm.458283 Transcribed locus, moderately similar to XP_001477892.1 PREDICTED: hypothetical protein [Mus musculus] 758.4727 901.1034 879.0435 175.8772 212.4538 268.9634 0.0029685358 1.96720 9.72076 7.75357 1349775 1455899_x_at 11 chr11:117827463-117827587 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 564.8040 648.9737 637.9292 306.8997 297.5614 299.8175 0.0026615378 1.03142 9.26696 8.23554 1349776 1455900_x_at 2 89.0 cM chr2:157942148-157942327 2 H1 IPA Tgm2 transglutaminase 2, C polypeptide 24.0086 26.5427 20.2236 10.4789 10.9173 8.7860 0.0013638124 1.22684 4.55123 3.32439 1349780 1455913_x_at 18 7.0 cM chr18:20832283-20832379 18 A2 chr18:20823913-20832820 18 A2 RSQ Mm.2108 NM_013697 1 1 22139 Ttr transthyretin (Ttr), mRNA. extracellular region;; hormone activity;; thyroid hormone generation;; transport extracellular region binding protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; hormone metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological quality;; transport 543.4584 568.1414 596.1502 197.4433 196.1357 215.3183 1.5438721e-05 1.48811 9.15189 7.66378 1342572 1456048_at 19 chr19:37097475-37097933 19 C2 chr19:37095780-37281783 19 C2 RSQ Mm.391176 NM_198300 1 1 208922 Cpeb3 cytoplasmic polyadenylation element binding protein 3 (Cpeb3), mRNA. nucleic acid binding;; nucleotide binding;; RNA binding binding nucleic acid binding;; nucleotide binding 728.9508 697.6797 718.0816 245.0972 349.4830 331.9656 0.015505654 1.22764 9.48137 8.25373 1342585 1456112_at 1 chr1:152260120-152261656 1 G1 chr1:152239982-152297059 1 G1 RSQ Mm.174256 NM_133780 2 2 108989 Tpr translocated promoter region (Tpr), mRNA. Pathways in cancer;; Thyroid cancer CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Thyroid Cancer [PATH:mmu05216] nuclear envelope cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle envelope;; organelle part 149.0025 140.8181 132.5810 61.0791 51.4573 76.0630 0.012919414 1.18019 7.13587 5.95568 1342588 1456120_at 2 chr2:125578627-125586066 2 F1 chr2:125562721-125608606 2 F1 RSQ Mm.138091 NM_177608 1 1 70354 RP23-367K9.1 Secisbp2l SECIS binding protein 2-like (Secisbp2l), mRNA. 501.8186 599.3431 644.3749 154.3001 149.3006 177.7507 0.00026770344 1.85488 9.17667 7.32179 1349871 1456212_x_at 11 E2 chr11:117827490-117827770 11 E2 IPA Mm.3468 Socs3 Suppressor of cytokine signaling 3 (Socs3), mRNA 355.6241 317.8186 347.0434 146.9297 155.7967 167.7478 0.00012259965 1.11753 8.40841 7.29088 1342601 1456262_at 9 F1 chr9:107662081-107662640 9 F1 UGA Mm.259197 83486 Rbm5 RNA binding motif protein 5 (Rbm5), mRNA apoptosis;; intracellular;; metal ion binding;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus;; RNA binding;; RNA splicing;; spliceosomal complex;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding ion binding;; nucleic acid binding;; nucleotide binding cellular process;; death;; metabolic process cell death;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 245.6717 257.8630 227.4618 67.3618 77.4053 73.8422 2.7606061e-05 1.74198 7.92684 6.18486 1342688 1457147_at 2 A3 chr2:20724458-20725017 2 A3 UGA Mm.237935 208618 RP23-436G18.1 Etl4 Enhancer trap locus 4, mRNA (cDNA clone IMAGE:4988846) cytoplasm;; embryonic skeletal system development;; multicellular organismal development cell;; cell part cell part;; intracellular;; intracellular part developmental process;; multicellular organismal process anatomical structure development;; embryonic development;; multicellular organismal development 191.3709 175.2338 163.9016 74.3027 76.0777 115.4933 0.0293226 1.02455 7.46335 6.43880 1342758 1459917_at 11 C chr11:84682500-84682776 11 C UGA Mm.356653 217039 RP23-293L24.5 Ggnbp2 Gametogenetin binding protein 2 (Ggnbp2), mRNA cell differentiation;; cytoplasm;; cytoplasmic vesicle;; multicellular organismal development;; nucleus;; protein binding;; spermatogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; vesicle binding protein binding cellular process;; developmental process;; multicellular organismal process;; reproduction;; reproductive process cellular developmental process;; gamete generation;; multicellular organismal development;; reproductive process;; sexual reproduction 257.4448 227.3657 216.2200 21.4183 48.0411 51.2702 0.019950355 2.63544 7.86445 5.22901 1342983 1460417_at 6 chr6:31115507-31168433 6 A3.3 RSQ XR_035177 2 1 232685 AB041803 PREDICTED: cDNA sequence AB041803 (AB041803), misc RNA. 948.9401 1019.0270 948.8652 337.6056 557.8939 380.7155 0.027861358 1.22587 9.92440 8.69854 1342988 1460426_at 3 F2.2|3 51.5 cM chr3:97550660-97557001 3 F2.2 UGA Mm.129840 83679 Pde4dip Phosphodiesterase 4D interacting protein (myomegalin), mRNA (cDNA clone IMAGE:4954590) cytoplasm;; Golgi apparatus;; nucleus;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding 279.4220 282.6819 257.7376 79.5299 77.8648 68.7668 6.4809409e-05 1.85971 8.09303 6.23332 1343058 1460670_at 18 3.0 cM chr18:12314622-12314869 18 A1 chr18:12287358-12315876 18 A1 RSQ Mm.28551 NM_024182 1 1 66878 Riok3 RIO kinase 3 (yeast) (Riok3), mRNA. ATP binding;; catalytic activity;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein serine/threonine kinase activity;; transferase activity binding;; catalytic activity nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 131.1863 89.3335 101.9436 21.4183 47.1964 34.6039 0.02066327 1.69800 6.72941 5.03141 1370809 1420312_s_at IPA Unknown 1895.7038 1694.9889 1660.2075 408.8358 536.3186 384.5423 0.002019694 1.99447 10.77091 8.77644 1350443 1428352_at 8 chr8:73359362-73359595 8 B3.3 chr8:73359036-73363619 8 B3.3 RSQ Mm.24215 NM_027560 1 1 70807 Arrdc2 arrestin domain containing 2 (Arrdc2), mRNA. 240.8718 233.6675 267.0862 108.5442 99.3836 127.4213 0.0020227366 1.15035 7.94720 6.79685 1350669 1428731_at 14 chr14:21368304-21368700 14 A3 chr14:21368133-21437576 14 A3 RSQ Mm.301173 NM_030180 1 1 78787 Usp54 ubiquitin specific peptidase 54 (Usp54), mRNA. ubiquitin thiolesterase activity;; ubiquitin-dependent protein catabolic process catalytic activity hydrolase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 3148.0404 2907.2683 2792.3091 1353.3186 1408.5972 1270.7445 8.4182152e-05 1.13305 11.52431 10.39126 1351041 1429300_at 12 chr12:112214932-112215222 12 F1 chr12:112213562-112217231 12 F1 RSQ Mm.250989 NM_175207 1 1 74251 Ankrd9 ankyrin repeat domain 9 (Ankrd9), mRNA. hydrolase activity catalytic activity hydrolase activity 461.0890 463.9440 455.9455 162.4676 201.0886 193.5748 0.0049356247 1.31566 8.84648 7.53081 1351107 1429399_at 18 A2 chr18:21141785-21142262 18 A2 UGA Mm.45980 67664 Rnf125 Rnf125 mRNA for RNF125 protein immune response;; intracellular;; ligase activity;; metal ion binding;; modification-dependent protein catabolic process;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; immune system process;; metabolic process;; response to stimulus catabolic process;; cellular metabolic process;; immune response;; macromolecule metabolic process;; primary metabolic process 708.0265 742.2007 711.3937 210.9011 355.9297 375.2283 0.041818758 1.24344 9.49261 8.24917 1351133 1429433_at 1 chr1:164650697-164670489 1 H2.1 chr1:164601915-164670687 1 H2.1 RSQ Mm.245446 NM_001081290 1 1 226562 Bat2d BAT2 domain containing 1 (Bat2d), mRNA. 355.7728 508.9285 391.4466 195.2738 207.4147 188.5620 0.015341461 1.07139 8.69293 7.62154 1351390 1429796_at 16 B3 chr16:34013284-34014058 16 B3 IPA 2210407G14Rik RIKEN cDNA 2210407G14 gene 520.6564 410.3654 427.7243 204.0964 235.2404 225.1735 0.0028133346 1.02650 8.81516 7.78866 1351428 1429843_at 4 chr4:133807078-133807598 4 D3 chr4:133807024-133810021 4 D3 RSQ Mm.100168 NM_001099296 1 1 72690 RP23-354H24.7 Grrp1 glycine/arginine rich protein 1 (Grrp1), mRNA. 425.2374 360.2150 356.5794 74.0493 95.1920 110.5775 0.0019271671 2.04361 8.56764 6.52403 1351449 1429870_at 3 A3 chr3:28259219-28259607 3 A3 UG5 Mm.126193 665113 Tnik TRAF2 and NCK interacting kinase, mRNA (cDNA clone MGC:183916 IMAGE:9087916) ATP binding;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; small GTPase regulator activity;; transferase activity binding;; catalytic activity;; enzyme regulator activity nucleoside binding;; nucleoside-triphosphatase regulator activity;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 428.0360 417.3065 423.6519 87.5274 129.9532 136.8044 0.011497717 1.86794 8.72443 6.85649 1351460 1429882_at 8 UGA Mm.440442 Transcribed locus, strongly similar to NP_001004371.1 cadherin 11, type 2, OB-cadherin (osteoblast) [Gallus gallus] 442.4852 395.3363 411.0854 156.9686 207.5717 211.9575 0.0090313136 1.12676 8.69991 7.57314 1351585 1430043_at 11 chr11:62095536-62096022 11 B2 chr11:62094974-62096109 11 B2 RSQ Mm.477526 NM_029704 1 1 72795 RP23-330N10.4 Ttc19 tetratricopeptide repeat domain 19 (Ttc19), transcript variant 2, mRNA. binding binding 126.4259 125.8538 138.9115 40.7640 48.6123 55.8235 0.0041342877 1.44017 7.02526 5.58509 1351678 1430152_at chr4:108997995-108998478 4 C7 IPA ESTs 314.2027 376.0961 358.6830 32.9315 33.8547 50.4968 0.0013911914 3.18542 8.44569 5.26027 1351838 1430352_at 6 D1 chr6:92795416-92795850 6 D1 UGA Mm.257557 101401 mCG_142056 Adamts9 MKIAA1312 protein endopeptidase activity;; extracellular space;; metallopeptidase activity;; positive regulation of melanocyte differentiation;; proteinaceous extracellular matrix;; proteolysis;; proteolysis;; regulation of pigmentation during development extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; pigmentation;; positive regulation of biological process;; regulation of biological process catabolic process;; cellular developmental process;; macromolecule metabolic process;; pigmentation during development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 94.2258 88.9107 86.6798 50.5080 41.9464 38.2963 0.0077925975 1.05397 6.48999 5.43602 1351845 1430362_at chr19:40547310-40547726 19 C3 IPA 5730409N24Rik RIKEN cDNA 5730409N24 gene 185.5672 155.8225 168.6519 57.2162 65.1021 58.6593 0.00012561096 1.49340 7.40582 5.91242 1351932 1430470_at 18 E1 chr18:61695210-61695524 18 E1 UGA Mm.234681 328967 4933429F08Rik Hypothetical protein cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; protein binding;; regulation of Rho protein signal transduction;; Rho guanyl-nucleotide exchange factor activity cell;; cell part cell part;; intracellular;; intracellular part binding;; enzyme regulator activity nucleoside-triphosphatase regulator activity;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 131.8270 148.5959 99.8584 38.0715 36.5450 49.5431 0.0021359019 1.60890 6.96652 5.35762 1352062 1430646_at 14 chr14:120800227-120800737 14 E4 IPA 5830407P18Rik RIKEN cDNA 5830407P18 gene 204.5408 181.0259 140.9264 71.5845 98.0169 66.7843 0.0076680861 1.15904 7.43837 6.27932 1352278 1430928_at chr19:20658957-20659524 19 B IPA 2900002J02Rik RIKEN cDNA 2900002J02 gene 51.3859 55.1204 71.3777 20.1391 29.0999 38.1653 0.038389897 1.05872 5.87507 4.81635 1352317 1430969_at 2 E1 chr2:90687892-90688410 2 E1 UG5 Mm.28023 56428 RP23-147D3.1 Mtch2 Mitochondrial carrier homolog 2 (C. elegans), mRNA (cDNA clone MGC:49067 IMAGE:5323415) integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part establishment of localization;; localization establishment of localization;; transport 147.2087 158.3059 147.2515 75.7915 62.8036 39.6774 0.035566368 1.39448 7.23681 5.84233 1352574 1431399_at 6 chr6:92876126-92887367 6 D1 UG5 Mm.158235 Transcribed locus, moderately similar to NP_891550.1 ADAM metallopeptidase with thrombospondin type 1 motif, 9 preproprotein [Homo sapiens] 84.3463 74.2800 84.2294 27.7300 22.3955 27.0462 0.00038755648 1.65785 6.33647 4.67862 1353251 1432461_at 10 chr10:22889870-22905127 10 A3 UGA Mm.444786 Transcribed locus 137.8102 117.6162 117.2482 26.5770 36.9735 44.4520 0.0079992511 1.81440 6.95263 5.13823 1353415 1432665_at chr13:110437515-110438024 13 D2.2 IPA 2210416J07Rik RIKEN cDNA 2210416J07 gene 1074.4042 1079.5964 1002.9459 129.7008 182.8163 168.3064 0.0019695126 2.72913 10.03854 7.30941 1353873 1433148_at chr7:137797332-137797814 7 F3 IPA 4930513N20Rik RIKEN cDNA 4930513N20 gene 3611.5964 3169.7510 3353.2092 952.8688 1145.3616 1426.4220 0.0070017812 1.54133 11.71997 10.17864 1354215 1433634_at 8 chr8:129114739-129115115 8 E2 chr8:129112193-129117336 8 E2 RSQ Mm.334918 XM_284454 2 1 270110 Irf2bp2 PREDICTED: interferon regulatory factor 2 binding protein 2, transcript variant 1 (Irf2bp2), mRNA. negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 988.7115 1066.1241 949.8691 475.1168 555.5922 434.5366 0.0034506098 1.04193 9.96638 8.92445 1354318 1433837_at 6 chr6:116602283-116602563 6 E3 chr6:116600716-116602812 6 E3 RSQ Mm.38231 NM_145980 1 1 213393 8430408G22Rik RIKEN cDNA 8430408G22 gene (8430408G22Rik), mRNA. 779.4604 807.8426 753.6875 84.6976 188.8789 228.8203 0.032996252 2.33948 9.60736 7.26788 1371171 1434202_a_at 14 A1 chr14:9128859-9128932 14 A1 UGA Mm.256058 268709 Fam107a Family with sequence similarity 107, member A (Fam107a), mRNA 104.3742 80.2214 104.8365 42.7094 44.5490 53.1875 0.003702117 1.03890 6.58118 5.54227 1354515 1434208_at 7 E1 chr7:107071073-107071571 7 E2 UGA Mm.323087 108937 Rnf169 MKIAA1991 protein 408.1550 374.8653 435.2250 194.3700 198.3156 186.0997 0.00092921241 1.07152 8.66294 7.59142 1354583 1434350_at 9 chr9:119880327-119880851 9 F4 chr9:119880283-119893776 9 F4 RSQ Mm.477982 NM_153287 1 1 215418 Csrnp1 cysteine-serine-rich nuclear protein 1 (Csrnp1), mRNA. apoptosis;; DNA binding;; face morphogenesis;; nucleus;; palate development;; platelet-derived growth factor receptor signaling pathway;; positive regulation of transcription from RNA polymerase II promoter;; post-embryonic development;; regulation of transcription, DNA-dependent;; skeletal system morphogenesis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell death;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; post-embryonic development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 563.5770 577.4852 580.6843 225.5258 257.7287 232.9203 0.0013384784 1.26772 9.16457 7.89685 1354973 1435084_at 18 chr18:21145335-21145848 18 A2 UGA Mm.475404 Transcribed locus 259.2286 274.6490 268.2120 88.2933 143.3830 132.1716 0.031129351 1.17084 8.06225 6.89141 1354998 1435125_at 12 chr12:104432850-104433264 12 E UG5 Mm.427936 Transcribed locus 413.2489 417.2527 394.7778 130.1712 144.4473 162.9311 0.0023781217 1.49125 8.67351 7.18226 1355019 1435163_at 17 chr17:32910266-32910799 17 B1 chr17:32902126-32925232 17 B1 RSQ Mm.38813 NM_172458 1 1 208292 Zfp871 zinc finger protein 871 (Zfp871), mRNA. metal ion binding;; nucleus;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 135.5040 155.7110 152.4115 16.3269 14.7692 13.4244 1.0147947e-05 3.31875 7.20558 3.88683 1355275 1435579_at 4 UG5 Mm.427140 Transcribed locus 181.0734 147.4729 143.5593 57.0160 55.9218 98.0122 0.031636183 1.20557 7.29008 6.08451 1355354 1435694_at 18 chr18:39535346-39535896 18 B3 chr18:39152798-39535939 18 B3 RSQ Mm.329396 NM_175164 1 1 71302 Arhgap26 Rho GTPase activating protein 26 (Arhgap26), mRNA. cell junction;; cytoplasm;; cytoskeleton;; GTPase activator activity;; intracellular;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle enzyme regulator activity enzyme activator activity;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 43.3778 69.0697 59.2464 20.9977 27.6490 29.9093 0.0126855 1.11789 5.81251 4.69461 1355485 1435918_at 14 A1 chr14:9130098-9130562 14 A1 UG5 Mm.256058 268709 Fam107a Family with sequence similarity 107, member A (Fam107a), mRNA 1027.4622 950.5746 990.8159 436.4683 420.9232 487.3028 0.00055060093 1.14473 9.95000 8.80527 1355678 1436202_at 19A chr19:5795727-5796151 19 A chr19:5795689-5802671 19 A RSQ NR_002847 1 1 72289 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), non-coding RNA. 91.4617 80.1248 92.2553 17.4268 21.8343 13.6373 0.0035846489 2.34186 6.45561 4.11375 1355703 1436240_at 6 chr6:49206477-49206881 6 B2.3 UGA Mm.461284 Transcribed locus 1439.1308 1208.2967 1258.4813 476.4218 720.8686 568.8199 0.011152967 1.16190 10.34240 9.18051 1356154 1437066_at 16 B4|16 28.9 cM chr16:43638539-43639055 16 B4 UGA Mm.136238 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone IMAGE:6484816) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 270.5834 272.5219 283.9297 89.6233 133.7463 99.4189 0.014298714 1.37831 8.10652 6.72820 1356345 1437410_at 5 F-G1 chr5:122021168-122021702 5 F UGA Mm.284446 11669 Aldh2 Aldehyde dehydrogenase 2, mitochondrial, mRNA (cDNA clone MGC:6764 IMAGE:3600875) 3-Chloroacrylic acid degradation;; Arginine and proline metabolism;; Ascorbate and aldarate metabolism;; beta-Alanine metabolism;; Butanoate metabolism;; Fatty acid metabolism;; Glycerolipid metabolism;; Glycolysis / Gluconeogenesis;; Histidine metabolism;; Limonene and pinene degradation;; Lysine degradation;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Ascorbate and aldarate metabolism [PATH:mmu00053] Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; C;; Propanoate metabolism;; Pyruvate metabolism;; Tryptophan metabolism;; Valine, leucine and isoleucine degradation aldehyde dehydrogenase (NAD) activity;; metabolic process;; mitochondrion;; oxidation reduction;; oxidoreductase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity oxidoreductase activity metabolic process oxidation reduction 124.7044 120.1719 125.0044 58.1335 57.9286 45.7317 0.0077292319 1.20151 6.94572 5.74421 1356438 1437584_at 17 chr17:47656286-47656414 17 C UGA Mm.453308 Transcribed locus 181.4579 167.1271 177.9079 55.7771 78.2885 75.5490 0.010072429 1.34387 7.45443 6.11056 1356463 1437638_at 17 chr17:23950981-23951487 17 A3.3 UGA Mm.436876 Transcribed locus, strongly similar to NP_780438.2 serine/arginine repetitive matrix 2 [Mus musculus] 105.1954 132.6316 120.1537 40.4244 43.2499 48.5488 0.0004148143 1.43460 6.89232 5.45772 1356486 1437676_at 11 C chr11:93911380-93911961 11 D UG5 Mm.260737 70834 RP23-378I13.3 Spag9 JNK-associated leucine-zipper protein activation of MAPK activity;; cytoplasm;; JUN kinase binding;; kinesin binding;; protein homooligomerization cell;; cell part cell part;; intracellular;; intracellular part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular component assembly;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 779.0014 790.6519 720.8822 328.5184 394.7576 357.8731 0.00098215751 1.08601 9.57533 8.48932 1356511 1437745_at 4 1.0 cM chr4:8679995-8712728 4 A1 chr4:8618067-8793957 4 A1 RSQ Mm.138792 NM_001081417 1 1 320790 RP23-464N23.1 Chd7 chromodomain helicase DNA binding protein 7 (Chd7), mRNA. adult heart development;; adult walking behavior;; ATP binding;; ATP-dependent helicase activity;; blood circulation;; blood vessel development;; camera-type eye development;; chromatin;; chromatin assembly or disassembly;; chromatin binding;; chromatin modification;; DNA binding;; ear morphogenesis;; embryonic hindlimb morphogenesis;; female genitalia development;; heart morphogenesis;; helicase activity;; hydrolase activity;; in utero embryonic development;; inner ear morphogenesis;; locomotory behavior;; nose development;; nucleic acid binding;; nucleotide binding;; nucleus;; palate development;; positive regulation of multicellular organism growth;; regulation of transcription, DNA-dependent;; sensory perception of sound;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; catalytic activity chromatin binding;; hydrolase activity;; nucleic acid binding;; nucleoside binding;; nucleotide binding biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus adult behavior;; anatomical structure development;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of growth;; positive regulation of multicellular organismal process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; system process 549.9189 502.4428 578.5162 246.4433 225.2063 296.3259 0.0036983719 1.09362 9.08403 7.99042 1356537 1437785_at 6 chr6:92722910-92723268 6 D1 chr6:92722692-92851435 6 D1 RSQ Mm.257557 NM_175314 1 1 101401 mCG_142056 Adamts9 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 (Adamts9), mRNA. endopeptidase activity;; extracellular space;; metallopeptidase activity;; positive regulation of melanocyte differentiation;; proteinaceous extracellular matrix;; proteolysis;; proteolysis;; regulation of pigmentation during development extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; pigmentation;; positive regulation of biological process;; regulation of biological process catabolic process;; cellular developmental process;; macromolecule metabolic process;; pigmentation during development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 241.5616 238.8618 253.0334 95.2203 87.3523 134.0364 0.020883677 1.23700 7.93315 6.69615 1356556 1437821_at chr18:38032193-38032756 18 B3 IPA Mus musculus 7 days embryo whole body cDNA, RIKEN full-length enriched library, clone:C430005H19 product:unknown EST, full insert sequence. 614.0041 631.9723 611.5086 241.2458 335.0650 303.7405 0.015343183 1.09090 9.27402 8.18312 1356570 1437862_at 12 D1 chr12:85004241-85004781 12 D1 UGA Mm.46005 67039 Rbm25 RNA binding motif protein 25 (Rbm25), mRNA cytoplasm;; mRNA processing;; nucleic acid binding;; nucleotide binding;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding;; nucleotide binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 527.7630 507.7075 543.3741 179.5772 129.7851 134.6100 0.0050540946 1.84544 9.03913 7.19369 1356604 1437916_at 7 chr7:71051764-71051840 7 C UGA Mm.446212 Transcribed locus 109.7762 95.8878 82.4238 46.7740 50.9592 40.4182 0.0027310513 1.05695 6.57556 5.51861 1356620 1437941_at X F3-F4|X 72.0 cM UGA Mm.350712 110094 RP23-181L15.3 Phka2 CDNA clone IMAGE:40051010 Calcium signaling pathway;; Insulin signaling pathway CLASS Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] calmodulin binding;; carbohydrate metabolic process;; glycogen metabolic process;; kinase activity;; membrane;; plasma membrane cell;; cell part cell part;; membrane binding;; catalytic activity protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1760.6113 1688.1422 1704.0489 500.2920 974.9365 618.8171 0.040624245 1.35622 10.74594 9.38972 1356671 1438039_at 12 17.0 cM chr12:52899719-52903413 12 C1 chr12:52844708-52930523 12 C1 RSQ Mm.249391 NM_144788 1 1 207304 Hectd1 HECT domain containing 1 (Hectd1), mRNA. ligase activity;; modification-dependent protein catabolic process;; neural tube closure catalytic activity ligase activity anatomical structure formation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; catabolic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process 174.5514 211.3018 208.5287 88.3581 116.4891 84.9178 0.0061351967 1.04581 7.62492 6.57911 1356722 1438121_at 11 B1.3 chr11:51555742-51556242 11 B1.3 UG5 Mm.33878 77371 RP23-79E13.2 Sec24a Sec24 related gene family, member A (S. cerevisiae), mRNA (cDNA clone IMAGE:40097170) COPII vesicle coat;; cytoplasm;; endoplasmic reticulum;; ER to Golgi vesicle-mediated transport;; Golgi apparatus;; intracellular protein transport;; membrane;; protein binding;; protein transport;; transport;; vesicle-mediated transport;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; protein complex;; vesicle binding ion binding;; protein binding cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; transport;; vesicle-mediated transport 43.9875 49.5882 49.9422 16.3634 25.9153 28.5040 0.04399559 1.05730 5.57771 4.52041 1356731 1438130_at 11 B5 chr11:83312602-83313120 11 C UG5 Mm.181050 70439 RP23-249K18.5 Taf15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, mRNA (cDNA clone MGC:169215 IMAGE:8860610) 1701.3080 1762.8147 1793.7734 602.4358 785.0145 649.9297 0.0052720053 1.37650 10.77496 9.39846 1371369 1438157_s_at 12 chr12:56590865-56590958 12 C1 chr12:56590395-56593634 12 C1 RSQ Mm.170515 NM_010907 1 1 18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA. Acetylation and Deacetylation of RelA in The Nucleus;; Activation of PKC through G protein coupled receptor;; AKT Signaling Pathway;; ATM Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; CD40L Signaling Pathway;; Double Stranded RNA Induced Gene Expression;; Erythropoietin mediated neuroprotection through NF-kB;; fMLP induced chemokine gene expression in HMC-1 cells;; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Influence of Ras and Rho proteins on G1 to S Transition;; Keratinocyte Differentiation;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; NF-kB Signaling Pathway;; NFkB activation by Nontypeable Hemophilus influenzae;; Signal transduction through IL1R;; T Cell Receptor Signaling Pathway;; The 4-1BB-dependent immune response;; TNF/Stress Related Signaling;; TNFR2 Signaling Pathway;; Toll-Like Receptor Pathway Adipocytokine signaling pathway;; Apoptosis;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Chronic myeloid leukemia;; Neurotrophin signaling pathway;; Pathways in cancer;; Prostate cancer;; Small cell lung cancer CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cytoplasm;; cytosol;; lipopolysaccharide-mediated signaling pathway;; negative regulation of myeloid cell differentiation;; negative regulation of NF-kappaB transcription factor activity;; negative regulation of Notch signaling pathway;; NF-kappaB binding;; nucleotide-binding oligomerization domain containing 1 signaling pathway;; nucleotide-binding oligomerization domain containing 2 signaling pathway;; nucleus;; protein import into nucleus, translocation;; regulation of cell proliferation;; response to exogenous dsRNA;; response to lipopolysaccharide;; response to muramyl dipeptide;; toll-like receptor 4 signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus activation of immune response;; anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune response;; immune system development;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of immune system process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; regulation of response to stimulus;; regulation of transcription regulator activity;; response to biotic stimulus;; response to chemical stimulus;; response to other organism;; response to stress;; transport 208.7671 257.2898 262.8741 30.2697 54.2200 104.1772 0.049018715 2.12259 7.91708 5.79448 1356746 1438186_at chr3:141971528-141972059 3 H1 IPA ESTs 429.2583 424.0141 422.9852 153.5402 168.4269 187.4452 0.003711245 1.32979 8.73271 7.40293 1356796 1438268_at 2 chr2:37230581-37232466 2 B chr2:37225588-37278423 2 B RSQ Mm.288785 NM_001100591 1 1 319817 RP23-321B3.1 Rc3h2 ring finger and CCCH-type zinc finger domains 2 (Rc3h2), mRNA. cytoplasm;; DNA binding;; membrane;; metal ion binding;; nucleic acid binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding ion binding;; nucleic acid binding;; protein binding 112.0441 100.2652 100.1906 34.8471 20.4210 29.6377 0.01071527 1.91263 6.70073 4.78810 1356817 1438301_at 15 chr15:64021278-64021774 15 D1 UGA Mm.448964 Transcribed locus 379.9297 332.4683 360.5058 133.1772 193.6487 158.6500 0.010521545 1.15878 8.48018 7.32140 1356946 1438519_at 16 chr16:20099161-20099591 16 A3 chr16:20097559-20099755 16 A3 RSQ XM_001476089 2 2 100046372 LOC100046372 PREDICTED: hypothetical protein LOC100046372 (LOC100046372), mRNA. 91.2653 54.7078 50.0110 22.4752 26.6681 26.3432 0.030767165 1.32772 5.97661 4.64889 1356987 1438590_at 15 F1 chr15:97577164-97577499 15 F1 UGA Mm.24028 223864 Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), mRNA Phospholipase C-epsilon pathway Leukocyte transendothelial migration;; Long-term potentiation CLASS Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670] Cellular Processes; Nervous System; Long-term potentiation [PATH:mmu04720] cAMP binding;; cAMP-dependent protein kinase complex;; cAMP-dependent protein kinase regulator activity;; cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; membrane;; nucleotide binding;; regulation of protein amino acid phosphorylation;; regulation of small GTPase mediated signal transduction;; small GTPase mediated signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; nucleoside binding;; nucleoside-triphosphatase regulator activity;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 500.5888 478.8030 491.4576 162.3036 218.4950 235.4287 0.015232339 1.27285 8.93723 7.66438 1357053 1438739_at 6 chr6:87797947-87798375 6 D1 UGA Mm.442804 Transcribed locus 384.0551 394.5174 386.0964 172.9121 187.6682 216.5964 0.007821902 1.01904 8.60064 7.58160 1357081 1438781_at 3 G3 chr3:133142044-133142441 3 G3 UGA Mm.347816 214133 Tet2 Tet oncogene family member 2, mRNA (cDNA clone IMAGE:4977050) cell cycle;; iron ion binding;; kidney development;; metal ion binding;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; post-embryonic development binding;; catalytic activity ion binding;; oxidoreductase activity cellular process;; developmental process;; metabolic process;; multicellular organismal process anatomical structure development;; cell cycle;; multicellular organismal development;; oxidation reduction;; post-embryonic development 149.2430 133.0901 116.4069 46.4102 73.6290 65.8165 0.01572487 1.12062 7.04694 5.92632 1357089 1438798_at 7 chr7:35070296-35070877 7 B1 chr7:35021732-35070628 7 B1 RSQ Mm.476734 NM_172741 1 1 233103 RP23-349I9.6 4931406P16Rik RIKEN cDNA 4931406P16 gene (4931406P16Rik), mRNA. 146.0964 137.0612 138.6835 64.3738 63.9156 78.6038 0.0055560126 1.03403 7.13503 6.10101 1357233 1439095_at 3 H4 chr3:157687705-157688252 3 H4 UGA Mm.223946 69207 Sfrs11 Splicing factor, arginine/serine-rich 11, mRNA (cDNA clone IMAGE:3154169) 266.1691 215.9390 208.8900 92.0282 96.2282 108.5102 0.0014930116 1.21440 7.83909 6.62469 1357241 1439106_at 4 chr4:55094004-55094435 4 B3 chr4:54960816-55096435 4 B3 RSQ Mm.102904 NM_172867 1 1 242466 RP23-281K3.2 Zfp462 zinc finger protein 462 (Zfp462), mRNA. negative regulation of DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 2351.9611 2631.1866 2621.2210 901.5860 852.0092 863.7312 0.0001851629 1.53723 11.30572 9.76850 1357272 1439153_at 13 chr13:47342806-47343264 13 A5 UGA Mm.444782 Transcribed locus 567.2075 499.6368 505.6848 238.2421 228.9852 275.1910 0.00065086234 1.08496 9.03152 7.94656 1357279 1439161_at 19 A chr19:3483536-3484088 19 A UGA Mm.284686 52036 Saps3 SAPS domain family, member 3 (Saps3), mRNA cytoplasm;; nucleus;; protein phosphatase binding;; regulation of phosphoprotein phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process cellular metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 3296.2708 3507.5675 3515.1346 845.2340 1082.5445 1281.3665 0.0087125715 1.70512 11.74741 10.04230 1357281 1439163_at 9 A5.3|9 23.0 cM chr9:48462424-48462942 9 A5.3 UG5 Mm.457803 235320 Zbtb16 PLZF gene Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer anterior/posterior pattern formation;; DNA binding;; embryonic hindlimb morphogenesis;; embryonic limb morphogenesis;; embryonic pattern specification;; forelimb morphogenesis;; leg morphogenesis;; male germ-line stem cell division;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of transcription, DNA-dependent;; nucleus;; nucleus;; positive regulation of apoptosis;; protein binding;; protein binding;; regulation of transcription;; skeletal system development;; specific transcriptional repressor activity;; transcriptional repressor complex;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription repressor activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell death;; cell division;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; sexual reproduction 72.2247 79.7091 73.1629 37.0535 36.0349 37.2588 0.00073666302 1.02725 6.22804 5.20079 1357282 1439165_at 9 chr9:59325563-59326112 9 B UG5 Mm.446631 Transcribed locus 254.4991 276.2337 263.5754 131.6521 104.2132 138.9178 0.0093808647 1.09376 8.04778 6.95402 1357416 1439349_at 10 C1 chr10:79534037-79534504 10 C1 UGA Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 1726.9546 1713.5049 1746.5719 698.8299 946.4558 899.3651 0.016242673 1.03970 10.75569 9.71598 1357444 1439477_at 11 chr11:51807342-51807651 11 B1.3 UGA Mm.440651 Transcribed locus 213.3186 210.7704 216.1125 84.2190 81.7391 101.4926 0.0054741357 1.26592 7.73734 6.47142 1357539 1439586_at 16 chr16:43565603-43566016 16 B4 UGA Mm.402642 Transcribed locus 287.8793 290.2378 297.8017 133.4478 152.0964 138.6017 0.0016600193 1.04828 8.18954 7.14126 1357600 1439652_at chr11:117524613-117525118 11 E2 IPA Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920011F17 product:unclassifiable, full insert sequence. 110.7813 85.4080 84.8063 31.3987 33.7911 40.7677 0.0012292684 1.40447 6.53799 5.13352 1357845 1439922_at 18 D3 chr18:57546777-57547286 18 D3 UG5 Mm.29889 73137 Prrc1 Proline-rich coiled-coil 1, mRNA (cDNA clone MGC:12103 IMAGE:3709357) Golgi apparatus;; identical protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding 138.5654 117.8266 118.2776 58.5171 64.6572 58.5322 0.00084064381 1.04143 6.96033 5.91889 1357924 1440013_at 2 chr2:102167076-102167568 2 E2 UGA Mm.450285 Transcribed locus 63.2457 54.4033 63.3116 21.4183 21.5015 23.5698 0.00023765921 1.44230 5.91097 4.46867 1357927 1440016_at chr3:116216915-116217450 3 G1 IPA ESTs 60.8887 39.5900 54.8053 21.6634 21.8509 32.6299 0.018810636 1.03216 5.67047 4.63831 1358021 1440111_at chr2:52800127-52800424 2 C1.1 IPA ESTs 27.4909 29.1170 18.4141 9.1428 8.3395 7.8130 0.011683515 1.54298 4.61580 3.07283 1371520 1440173_x_at 1 H2.2|1 86.6 cM UGA Mm.3337 20344 Selp Selectin, platelet (Selp), mRNA Eph Kinases and ephrins support platelet aggregation;; Monocyte and its Surface Molecules Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] binding;; calcium-dependent protein binding;; cell adhesion;; external side of plasma membrane;; glycoprotein binding;; heterophilic cell adhesion;; inflammatory response;; integral to membrane;; leukocyte adhesion;; leukocyte tethering or rolling;; membrane;; membrane fraction;; platelet alpha granule membrane;; protein binding;; sialic acid binding;; sugar binding cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; cell surface;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding carbohydrate binding;; protein binding biological adhesion;; cellular process;; immune system process;; localization;; locomotion;; response to stimulus cell adhesion;; cell motility;; cell motion;; leukocyte migration;; localization of cell;; response to external stimulus;; response to stress 775.5994 764.1519 819.7624 56.0065 72.1527 166.4367 0.021382937 3.16554 9.61865 6.45311 1358216 1440347_at 8 chr8:79889434-79889899 8 C1 UGA Mm.438679 Transcribed locus 135.1414 138.6205 149.7337 23.0892 30.6690 32.5484 0.0024259844 2.30907 7.13986 4.83079 1358233 1440365_at chr16:37873054-37873603 16 B3 IPA ESTs 67.4997 55.0017 47.4149 21.9513 31.3537 24.2717 0.0060147302 1.13249 5.80849 4.67600 1358415 1440553_at 4 D2.3 chr4:131399933-131400415 4 D2.3 UG5 Mm.192706 26922 Mecr Mitochondrial trans-2-enoyl-CoA reductase, mRNA (cDNA clone MGC:6611 IMAGE:3488760) Fatty acid elongation in mitochondria;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Fatty acid elongation in mitochondria [PATH:mmu00062] binding;; catalytic activity;; cytosol;; fatty acid biosynthetic process;; ligand-dependent nuclear receptor binding;; lipid biosynthetic process;; metabolic process;; mitochondrion;; nucleus;; oxidation reduction;; oxidoreductase activity;; trans-2-enoyl-CoA reductase (NADPH) activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity;; protein binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; oxidation reduction;; primary metabolic process 316.2382 282.8826 290.0800 67.8665 91.5648 100.6155 0.0057746511 1.79173 8.20974 6.41802 1358427 1440565_at chr16:43560712-43561239 16 B4 IPA Mus musculus adult male liver tumor cDNA, RIKEN full-length enriched library, clone:C730020C12 product:unknown EST, full insert sequence. 391.5528 381.2644 399.2307 140.9491 241.4751 125.7445 0.048150103 1.26656 8.60960 7.34304 1358496 1440635_at 8 B3.3 chr8:64162534-64162869 8 B3.1 UG5 Mm.29933 72333 Palld Palladin, cytoskeletal associated protein, mRNA (cDNA clone IMAGE:4947562) actin binding;; actin filament;; cytoplasm;; cytoskeleton;; nucleus cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding 139.3842 134.4529 127.6467 62.4265 59.6349 66.7521 8.1370809e-05 1.08899 7.06330 5.97430 1358631 1440776_at 5 C3.1 chr5:67139353-67139604 5 C3.1 UGA Mm.374778 77569 Limch1 LIM and calponin homology domains 1 (Limch1), mRNA actin binding;; actomyosin structure organization;; metal ion binding;; zinc ion binding binding ion binding;; protein binding cellular component organization;; cellular process actin filament-based process;; organelle organization 257.8080 263.8041 273.6190 61.1835 86.1201 84.9668 0.0069251929 1.79244 8.04983 6.25739 1358665 1440847_at 15 chr15:58884333-58884882 15 D1 UGA Mm.394414 Transcribed locus 452.5408 423.2220 456.1665 179.4001 214.7810 188.7075 0.0011806924 1.19561 8.79353 7.59792 1358736 1440926_at 5 chr5:148446897-148447256 5 G3 UGA Mm.458302 Transcribed locus 117.2209 137.9853 112.7852 56.3572 58.0596 66.1610 0.0010577534 1.02500 6.93296 5.90797 1358826 1441026_at 14 chr14:57248034-57260154 14 C3 chr14:57194455-57278635 14 C3 RSQ Mm.379357 NM_001145978 1 1 328417 Parp4 poly (ADP-ribose) polymerase family, member 4 (Parp4), mRNA. Base excision repair CLASS Genetic Information Processing; Replication and Repair; Base excision repair [PATH:mmu03410] enzyme binding;; nucleus;; protein binding;; spindle;; telomere maintenance via telomerase cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological quality 108.4439 93.7802 97.4960 32.6699 34.8461 27.8261 0.00034454853 1.65604 6.63976 4.98373 1358842 1441042_at 18 B3|18 19.0 cM chr18:39006345-39006814 18 B3 UGA Mm.241282 14164 Fgf1 Fibroblast growth factor 1, mRNA (cDNA clone MGC:46904 IMAGE:5137246) BTG family proteins and cell cycle regulation MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Melanoma [PATH:mmu05218];; Pathways in cancer;; Regulation of actin cytoskeleton angiogenesis;; cell differentiation;; cell proliferation;; extracellular space;; growth factor activity;; heparin binding;; induction of an organ;; lung development;; multicellular organismal development;; positive regulation of epithelial cell proliferation;; positive regulation of protein amino acid phosphorylation;; protein binding;; proteinaceous extracellular matrix extracellular region;; extracellular region part extracellular matrix;; extracellular region part;; extracellular space binding carbohydrate binding;; pattern binding;; protein binding anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 353.4556 318.8421 345.8223 167.2319 158.5474 166.0408 0.00022905329 1.04870 8.40532 7.35662 1358975 1441185_at 11 chr11:88291497-88292043 11 C UGA Mm.443787 Transcribed locus 396.8003 359.5980 355.7399 170.8752 110.9951 128.5818 0.010891839 1.45983 8.53240 7.07256 1359017 1441228_at 6 G1 chr6:134936253-134936706 6 G1 UG5 Mm.296104 381823 Apold1 Apolipoprotein L domain containing 1 (Apold1), mRNA 291.3669 266.1877 253.6830 102.5081 103.5356 127.6522 0.0013086952 1.28674 8.07663 6.78988 1359019 1441230_at chr3:27511416-27511951 3 A3 IPA ESTs 373.9311 364.5717 351.0311 185.9330 171.8159 152.2308 0.0030862566 1.09956 8.50405 7.40449 1359105 1441331_at 10 chr10:13699848-13700364 10 A2 UGA Mm.395880 Transcribed locus 82.9808 71.6041 81.4700 20.5868 18.3784 21.2249 2.8870082e-05 1.97120 6.29496 4.32376 1359158 1441388_at 18 E2|18 44.0 cM chr18:70788193-70788698 18 E2 UGA Mm.322 17191 Mbd2 Methyl-CpG binding domain protein 2 (Mbd2), mRNA cellular protein complex assembly;; chromatin;; chromatin binding;; cytoplasm;; DNA binding;; heterochromatin;; histone deacetylase complex;; maternal behavior;; methyl-CpG binding;; mRNA binding;; negative regulation of transcription from RNA polymerase II promoter;; nucleolus;; nucleus;; positive regulation of Wnt receptor signaling pathway;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; siRNA binding;; transcription cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding chromatin binding;; nucleic acid binding;; nucleotide binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus behavior;; biosynthetic process;; cell communication;; cell proliferation;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organism reproduction;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive behavior;; reproductive process;; reproductive process in a multicellular organism 72.4076 91.0624 73.1543 39.7298 27.8208 32.8831 0.0034229073 1.24340 6.29324 5.04984 1359231 1441467_at 3 chr3:138436873-138437414 3 H1 UG5 Mm.417274 Transcribed locus 241.4638 243.5553 254.9852 46.4991 91.8810 74.2362 0.022968092 1.85439 7.94601 6.09163 1359294 1441531_at 2 F3|2 77.0 cM chr2:135486868-135487311 2 F3 UGA Mm.38009 18798 RP23-7A19.1 Plcb4 Phospholipase C beta 4 [Mus musculus], mRNA sequence Alzheimer's disease;; Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Huntington's disease CLASS Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism [PATH:mmu00562] Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Environmental Information Processing; Signal Tr;; Inositol phosphate metabolism;; Long-term depression;; Long-term potentiation;; Melanogenesis;; Metabolic pathways;; Phosphatidylinositol signaling system;; Vascular smooth muscle contraction;; Wnt signaling pathway dendrite;; microsome;; nucleus;; postsynaptic density;; protein binding;; signal transducer activity;; signal transduction;; smooth endoplasmic reticulum cell;; cell part;; organelle;; organelle part;; synapse;; synapse part cell fraction;; cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; postsynaptic density;; synapse part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 189.7186 161.7630 199.1457 54.8421 71.6546 79.9890 0.003854652 1.42707 7.51438 6.08731 1359354 1441592_at 10 chr10:66595201-66595683 10 B5.1 UGA Mm.440483 Transcribed locus 217.6730 212.3186 189.2485 96.2681 86.7958 112.8333 0.002831199 1.07122 7.68675 6.61553 1359356 1441594_at chr5:104199317-104199794 5 E5 IPA Mus musculus 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130072L14 product:unclassifiable, full insert sequence. 111.9263 105.7460 109.6878 49.1933 37.9325 42.1065 0.0047630848 1.34880 6.76937 5.42057 1359404 1441643_at 18 D2|18 chr18:57081974-57082425 18 D3 UGA Mm.312623 320253 March3 Membrane-associated ring finger (C3HC4) 3, mRNA (cDNA clone MGC:130168 IMAGE:40052074) cytoplasmic vesicle;; endocytosis;; endosome;; integral to membrane;; ligase activity;; membrane;; metal ion binding;; modification-dependent protein catabolic process;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; vesicle binding;; catalytic activity ion binding;; ligase activity cellular component organization;; cellular process;; establishment of localization;; localization;; metabolic process catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; membrane organization;; primary metabolic process;; transport;; vesicle-mediated transport 121.2243 103.9130 86.9045 34.3091 42.7821 44.3701 0.0019056895 1.35705 6.68738 5.33032 1359413 1441653_at 7 F3 UG5 Mm.428042 100043597 Srcap PREDICTED: Mus musculus similar to Snf2-related CBP activator protein (LOC100043597), mRNA 556.0856 515.3655 490.3606 40.4972 46.7996 52.1493 9.9035528e-05 3.49119 9.02210 5.53092 1359551 1441799_at chr17:28557117-28557366 17 A3.3 IPA ESTs 244.5804 205.8857 190.7352 83.8888 88.7387 78.5967 0.0017659569 1.34567 7.73176 6.38610 1359571 1441823_at 14 A3 chr14:26357806-26357946 14 A3 UGA Mm.227484 328365 Zmiz1 Zinc finger, MIZ-type containing 1, mRNA (cDNA clone MGC:86031 IMAGE:6856060) artery morphogenesis;; cell aging;; cytoplasm;; developmental growth;; heart morphogenesis;; in utero embryonic development;; metal ion binding;; nucleus;; positive regulation of fibroblast proliferation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; vasculogenesis;; vitellogenesis;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; protein binding biological regulation;; cellular component organization;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process aging;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell aging;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytoplasm organization;; developmental growth;; embryonic development;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 65.0842 60.3673 62.0749 21.0842 25.0583 23.2114 0.00060071969 1.43793 5.96529 4.52736 1359586 1441858_at IPA Unknown 321.5302 286.6683 313.9896 89.1899 115.1755 124.6443 0.0049555559 1.49948 8.26221 6.76272 1359741 1442102_at chr15:81730419-81730848 15 E1 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 196.3524 209.9480 192.2458 78.2709 80.3196 70.8618 7.700182e-05 1.38433 7.63933 6.25501 1359835 1442198_at chr1:140431997-140432313 1 E4 IPA ESTs 216.7157 181.0322 152.3227 78.5700 83.5973 84.6532 0.012801373 1.14199 7.50358 6.36159 1359883 1442248_at 15 chr15:27843701-27844181 15 B1 UGA Mm.453300 Transcribed locus 278.1816 346.1456 405.7709 99.0323 122.0745 107.6189 0.0024031147 1.63614 8.40655 6.77041 1359891 1442256_at 14 B|14 11.0 cM UGA Mm.2314 18753 Prkcd Protein kinase C delta HIV-I Nef: negative effector of Fas and TNF;; Keratinocyte Differentiation Chemokine signaling pathway;; Fc epsilon RI signaling pathway;; GnRH signaling pathway;; Neurotrophin signaling pathway;; Tight junction;; Type II diabetes mellitus CLASS Cellular Processes; Cell Communication; Tight junction [PATH:mmu04530] Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] Cellular Processes; Immune System; Fc epsilon RI signaling pathway [PATH:mmu04664] C;; Vascular smooth muscle contraction ATP binding;; B cell proliferation;; cytoplasm;; diacylglycerol binding;; immunoglobulin mediated immune response;; insulin receptor substrate binding;; interleukin-10 production;; interleukin-12 production;; intracellular signaling cascade;; kinase activity;; membrane;; metal ion binding;; negative regulation of insulin receptor signaling pathway;; negative regulation of peptidyl-tyrosine phosphorylation;; nucleotide binding;; protein amino acid phosphorylation;; protein kinase activity;; protein kinase C activity;; protein serine/threonine kinase activity;; transferase activity;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding;; catalytic activity ion binding;; lipid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell activation;; cell communication;; cell proliferation;; cellular metabolic process;; cellular response to stimulus;; cytokine production;; immune effector process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; negative regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 60.4668 45.0442 41.7707 25.8122 24.0430 19.7156 0.0077266318 1.07232 5.59859 4.52626 1359911 1442277_at 19 A|19 3.0 cM chr19:3865272-3865840 19 A UGA Mm.225505 12660 Chka Choline kinase alpha, mRNA (cDNA clone IMAGE:3582342) Glycerophospholipid metabolism;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] ATP binding;; choline kinase activity;; cholinesterase activity;; cytoplasm;; ethanolamine kinase activity;; kinase activity;; nucleotide binding;; phosphatidylcholine biosynthetic process;; protein homodimerization activity;; transferase activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; organophosphate metabolic process;; primary metabolic process 321.3202 260.5442 255.1722 80.0638 81.4781 69.1425 0.00026836207 1.85522 8.11619 6.26097 1360020 1442395_at 1 chr1:34085393-34085906 1 B UGA Mm.436779 Transcribed locus 1144.4827 1230.9785 1257.3657 324.0741 254.3387 247.1169 0.0014879999 2.14747 10.24075 8.09328 1360313 1442710_at chr3:142052865-142053312 3 H1 IPA ESTs 54.6833 62.9802 70.8922 25.3861 22.8807 21.2392 0.00073960748 1.43558 5.96580 4.53023 1360328 1442725_at 11 UG5 Mm.419280 Transcribed locus 136.6911 118.8242 139.6533 34.6420 28.8970 46.9103 0.0063581856 1.86468 7.03772 5.17304 1360350 1442750_at 13 A1 chr13:14064362-14064580 13 A1 UG5 Mm.21686 97884 B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2, mRNA (cDNA clone MGC:103263 IMAGE:30735904) acetylgalactosaminyltransferase activity;; galactosyltransferase activity;; Golgi apparatus;; integral to membrane;; membrane;; protein amino acid glycosylation;; transferase activity;; transferase activity, transferring glycosyl groups;; UDP-N-acetylgalactosamine metabolic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 38.9279 43.6176 37.2293 17.1394 20.8037 20.8019 0.0012930752 1.03042 5.31598 4.28555 1360461 1442880_at 16 chr16:34559830-34560160 16 B3 UGA Mm.24752 Transcribed locus 151.4427 174.0500 190.4266 65.3367 61.8438 43.4317 0.0044158984 1.61267 7.41969 5.80702 1360495 1442916_at 8 chr8:70533034-70533494 8 B3.3 UGA Mm.403977 Transcribed locus 88.2901 102.2695 64.8960 25.1054 37.9253 30.4765 0.005242261 1.44528 6.38682 4.94155 1360542 1442967_at 8 chr8:80016360-80016899 8 C1 UGA Mm.394850 Transcribed locus 279.1356 188.7146 225.3057 65.4049 56.6737 66.3821 0.0026716611 1.86399 7.83354 5.96955 1360637 1443069_at 11 chr11:108041099-108041513 11 E1 UGA Mm.447682 Transcribed locus 364.9948 405.3497 366.8801 118.7726 137.7341 120.9021 8.4273605e-05 1.59281 8.56464 6.97183 1360668 1443100_at 14 chr14:18661754-18662090 14 A2 UGA Mm.406687 Transcribed locus 124.7546 127.0538 135.7793 64.6796 61.8438 61.9189 0.00010018032 1.03975 7.01246 5.97270 1360728 1443160_at 7 F2 chr7:117590515-117591052 7 F1 UGA Mm.102970 319934 Sbf2 SET binding factor 2, mRNA (cDNA clone IMAGE:4527932) phosphatase binding;; phosphatase regulator activity;; phosphoinositide binding;; protein homodimerization activity;; protein tetramerization;; vacuolar membrane cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; enzyme regulator activity lipid binding;; phosphatase regulator activity;; protein binding anatomical structure formation;; cellular component biogenesis;; cellular component organization cellular component assembly;; macromolecular complex subunit organization;; protein complex biogenesis 30.7800 35.1871 39.0084 14.0207 18.2806 13.0802 0.0037708071 1.21852 5.12220 3.90368 1360780 1443212_at chr8:75853675-75854162 8 B3.3 IPA ESTs 652.0214 582.2813 614.0051 99.3446 119.9860 182.1062 0.010945774 2.24891 9.26548 7.01658 1360856 1443289_at 13 chr13:110571699-110572038 13 D2.2 UGA Mm.438644 Transcribed locus 58.8973 59.3283 65.6579 32.5111 27.7499 28.6288 0.00043935261 1.05034 5.93589 4.88556 1360905 1443341_at chr6:86724341-86724697 6 D1 IPA ESTs 85.2639 94.8588 93.1718 32.2810 36.3479 55.1627 0.032913456 1.18045 6.50780 5.32734 1360981 1443430_at 10 chr10:94753539-94754027 10 C2 IPA Mm.218009 Transcribed locus, strongly similar to NP_034080.1 CASP2 and RIPK1 domain containing adaptor with death domain [Mus musculus] 350.3305 390.8186 426.0877 120.8400 146.7881 144.0995 0.00025352531 1.50416 8.59931 7.09516 1361015 1443471_at 16 B4|16 28.9 cM chr16:43613020-43613517 16 B4 UGA Mm.440824 56490 RP23-283M18.1 Zbtb20 Zinc finger and BTB domain containing 20, mRNA (cDNA clone MGC:35911 IMAGE:4971586) DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 157.6697 157.7437 159.7878 56.3572 51.3663 84.2719 0.025578227 1.34198 7.30740 5.96542 1361052 1443511_at 9 chr9:68763941-68764383 9 C UGA Mm.445349 Transcribed locus 84.4351 113.5318 115.0222 28.5328 34.8730 41.0085 0.0016603572 1.58535 6.69083 5.10548 1371794 1443721_x_at 10 C1 chr10:79529116-79529323 10 C1 UG5 Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 225.8753 254.2836 254.5912 103.0577 128.4636 118.2085 0.0014023899 1.07467 7.93391 6.85924 1361430 1443983_at 19 UGA Mm.440351 Transcribed locus 35.1562 28.1248 26.2691 9.9962 13.9907 16.2625 0.013547439 1.17118 4.88826 3.71708 1361482 1444037_at 18 chr18:66160219-66160695 18 E1 UG5 Mm.449042 Transcribed locus, strongly similar to NP_081676.1 lectin, mannose-binding, 1 [Mus musculus] 31.0269 33.4682 34.2422 12.8354 16.1381 19.1216 0.01877761 1.05543 5.03929 3.98386 1361501 1444057_at 1 chr1:130147437-130147962 1 E4 UGA Mm.446146 Transcribed locus 6737.7447 6963.3823 6968.6388 1966.7949 3930.4750 2831.6241 0.045474016 1.30025 12.75009 11.44984 1361527 1444083_at 2 44.0 cM chr2:76783445-76783867 2 C3 RSQ Mm.373672 NM_028004 2 1 22138 RP23-82M15.1 Ttn titin (Ttn), transcript variant N2-B, mRNA. A band;; adult heart development;; ATP binding;; calcium ion binding;; calmodulin binding;; cardiac myofibril assembly;; cytoplasm;; forward locomotion;; heart morphogenesis;; I band;; in utero embryonic development;; kinase activity;; M band;; magnesium ion binding;; metal ion binding;; muscle contraction;; muscle myosin complex;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; sarcomere;; sarcomere organization;; sarcomere organization;; somitogenesis;; striated muscle cell development;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity;; Z disc cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; locomotion;; metabolic process;; multicellular organismal process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; directional locomotion;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; pattern specification process;; primary metabolic process;; system process 611.1099 576.7075 648.2397 250.5562 265.7846 275.1798 5.7390476e-05 1.21334 9.25579 8.04244 1361549 1444107_at 12 chr12:85490277-85490794 12 D1 UGA Mm.394928 Transcribed locus 157.3806 159.4961 159.0004 66.3007 93.3418 76.0185 0.01876611 1.02823 7.30946 6.28123 1361862 1444430_at chr9:99407238-99407662 9 E3.3 IPA Mus musculus 13 days embryo lung cDNA, RIKEN full-length enriched library, clone:D430004H12 product:hypothetical protein, full insert sequence. 138.1638 128.4840 132.8384 49.6214 48.3193 59.7940 0.002699865 1.34662 7.05640 5.70978 1361879 1444447_at chr1:140464411-140464853 1 E4 IPA Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4932441M09 product:unknown EST, full insert sequence. 189.9336 207.4297 200.1280 70.2563 77.0484 70.3311 1.8731546e-05 1.45742 7.63687 6.17945 1361920 1444489_at 2 C2 UGA Mm.30928 78830 RP23-299A2.2 Slc25a12 Solute carrier family 25 (mitochondrial carrier, Aralar), member 12, mRNA (cDNA clone MGC:67718 IMAGE:6311836) binding;; calcium ion binding;; integral to membrane;; malate-aspartate shuttle;; membrane;; mitochondrial inner membrane;; mitochondrial inner membrane;; mitochondrion;; mitochondrion;; transport;; transporter activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; transporter activity ion binding cellular process;; establishment of localization;; localization;; metabolic process cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; oxidation reduction;; transport 58.0893 61.0574 70.6657 31.0597 26.9572 28.2050 0.00068229756 1.13593 5.97841 4.84248 1362015 1444587_at 13 chr13:110580551-110580864 13 D2.2 UGA Mm.437139 Transcribed locus 4566.3803 4608.2352 4578.5964 1362.5062 2017.7015 2183.0759 0.02390437 1.33494 12.16251 10.82756 1362062 1444638_at 2 44.0 cM chr2:76803223-76807243 2 C3 RSQ Mm.373672 NM_011652 2 1 22138 RP23-82M15.1 Ttn titin (Ttn), transcript variant N2-A, mRNA. A band;; adult heart development;; ATP binding;; calcium ion binding;; calmodulin binding;; cardiac myofibril assembly;; cytoplasm;; forward locomotion;; heart morphogenesis;; I band;; in utero embryonic development;; kinase activity;; M band;; magnesium ion binding;; metal ion binding;; muscle contraction;; muscle myosin complex;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; sarcomere;; sarcomere organization;; sarcomere organization;; somitogenesis;; striated muscle cell development;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity;; Z disc cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; structural constituent of cytoskeleton;; structural constituent of muscle;; transferase activity anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; locomotion;; metabolic process;; multicellular organismal process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; directional locomotion;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; pattern specification process;; primary metabolic process;; system process 209.2845 162.7633 175.4297 73.4184 77.6593 83.5096 0.0022333904 1.21656 7.50357 6.28701 1362074 1444651_at 11 chr11:65564609-65564943 11 B3 UGA Mm.445744 Transcribed locus 115.2145 114.1421 109.8215 37.3903 43.4746 39.5974 0.0006933171 1.49595 6.82063 5.32467 1362172 1444749_at 16 chr16:31305712-31306199 16 B2 UGA Mm.436754 Transcribed locus 1056.8681 1076.9852 991.0408 123.7372 125.1752 190.9852 0.0041699694 2.85830 10.02372 7.16542 1362387 1444973_at chr14:24571790-24572277 14 A3 IPA ESTs 220.0138 160.2974 191.6328 111.6598 80.3699 80.1381 0.0070529145 1.07743 7.56275 6.48532 1362396 1444982_at chr12:76442505-76443010 12 C3 IPA C230007H23Rik RIKEN cDNA C230007H23 gene 542.2619 507.4418 462.3202 103.7687 115.7316 127.6573 6.4710257e-05 2.12490 8.97423 6.84933 1362558 1445148_at chr1:55487728-55488266 1 C1.2 IPA Mus musculus 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230091K16 product:unknown EST, full insert sequence. 556.8844 510.7315 540.3797 58.1042 75.4649 128.1454 0.014282876 2.69851 9.06516 6.36665 1362797 1445395_at 11 chr11:108132382-108132923 11 E1 UGA Mm.443896 Transcribed locus 157.5952 129.5364 127.2414 61.1687 60.7533 67.3254 0.0023326654 1.12534 7.10291 5.97756 1362800 1445398_at 5 chr5:67306909-67307387 5 C3.1 UGA Mm.454791 Transcribed locus 364.6539 398.1917 373.8282 156.9860 175.3773 191.5861 0.0016343315 1.12109 8.56465 7.44355 1362845 1445443_at chr7:52694090-52694571 7 B4 IPA ESTs, Weakly similar to I58401 protein-tyrosine kinase (EC 2.7.1.112) JAK3 - mouse [M.musculus] 1152.8104 1269.0108 1241.8741 145.2623 151.5829 134.9756 1.4630501e-06 3.08523 10.25291 7.16768 1362958 1445562_at chr9:48638602-48638777 9 A5.3 IPA ESTs 68.7509 77.3092 71.9055 36.2197 34.3016 38.3882 0.00012639628 1.00080 6.18130 5.18050 1363080 1445695_at 13 chr13:45701247-45701513 13 A5 UGA Mm.453409 Transcribed locus 340.8929 316.1018 368.5697 58.7359 70.8420 97.8126 0.0058179453 2.20285 8.41440 6.21155 1363152 1445774_at chr14:24589566-24590021 14 A3 IPA Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330037B11 product:unknown EST, full insert sequence. 101.1707 101.9682 106.6829 40.9233 32.8096 48.3425 0.012455965 1.36123 6.68994 5.32871 1363186 1445809_at 10 chr10:23067802-23068323 10 A3 UGA Mm.444891 Transcribed locus 68.0409 79.0972 68.9475 22.1397 35.5882 26.0666 0.01281342 1.39176 6.16710 4.77534 1363227 1445850_at 1 F chr1:136676358-136676868 1 E4 UGA Mm.188709 329251 Ppp1r12b Protein phosphatase 1, regulatory (inhibitor) subunit 12B, mRNA (cDNA clone MGC:175633 IMAGE:40131049) Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] cytoplasm cell;; cell part cell part;; intracellular;; intracellular part 200.9565 174.0864 216.0408 73.5798 87.3461 91.4333 0.00075266438 1.22833 7.61652 6.38819 1363268 1445892_at 1 C5 chr1:93338360-93338775 1 D IPA Mm.218141 Per2 Period homolog 2 (Drosophila) (Per2), mRNA 120.1052 115.1138 129.2252 50.6661 68.7361 50.0121 0.01127872 1.11955 6.92294 5.80338 1363491 1446118_at chr17:30161295-30161855 17 A3.3 IPA ESTs 48.0810 41.6238 44.5490 17.5490 20.6898 18.4870 0.00020221884 1.24381 5.48135 4.23754 1363507 1446134_at chr15:66989390-66989885 15 D2 IPA ESTs 134.0971 122.2630 116.4261 34.0230 22.3451 35.0172 0.006668887 2.05464 6.95475 4.90011 1363536 1446167_at chr6:38733170-38733515 6 B1 IPA Mus musculus 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930417E23 product:unknown EST, full insert sequence. 381.5703 303.1981 314.4421 91.6713 117.2947 146.0780 0.0060224039 1.51120 8.37219 6.86100 1363613 1446245_at chr2:52721981-52722503 2 C1.1 IPA Mus musculus 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030463N01 product:unknown EST, full insert sequence. 146.7349 145.4297 148.3797 30.6667 41.7563 35.4552 0.0038241283 2.04132 7.19813 5.15682 1363652 1446284_at 15 D1 chr15:58871422-58871951 15 D1 UGA Mm.215481 211401 Mtss1 Metastasis suppressor 1, mRNA (cDNA clone IMAGE:5343395) actin binding;; actin filament organization;; actin filament polymerization;; cytoplasm;; cytoskeletal adaptor activity;; cytoskeleton;; filopodium assembly;; muscle organ development;; nervous system development;; SH3 domain binding;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding molecular adaptor activity;; protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process actin filament-based process;; anatomical structure development;; cell communication;; cell projection organization;; cellular component assembly;; cellular macromolecular complex subunit organization;; macromolecular complex subunit organization;; multicellular organismal development;; organelle organization;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process 348.4954 321.4219 319.5474 148.4307 122.0245 114.1632 0.0032576722 1.37119 8.36440 6.99321 1363714 1446346_at 6 chr6:92875090-92875609 6 D1 UGA Mm.158235 Transcribed locus, moderately similar to NP_891550.1 ADAM metallopeptidase with thrombospondin type 1 motif, 9 preproprotein [Homo sapiens] 170.1519 176.0408 197.3078 83.4458 67.6365 90.6181 0.0036767721 1.17684 7.49825 6.32141 1363783 1446417_at chr13:34020506-34021041 13 A3.3 IPA ESTs 258.9297 198.1867 208.9740 76.0590 64.5594 69.0432 0.00084682411 1.66109 7.78477 6.12368 1363787 1446421_at 3 chr3:68407435-68407941 3 E1 UGA Mm.448005 Transcribed locus 382.1519 379.8186 338.5408 94.2610 92.2798 88.5187 0.00010351446 1.99864 8.51679 6.51815 1363841 1446475_at 14 chr14:120692309-120692809 14 E4 UG5 Mm.453644 Transcribed locus 135.2879 117.4626 108.7614 35.0984 31.0789 44.2829 0.0014586484 1.72037 6.90699 5.18662 1363875 1446509_at chr2:131342326-131342825 2 F1 IPA B130066H01Rik RIKEN cDNA B130066H01 gene 114.3109 128.7509 127.2256 54.0989 73.0710 58.7465 0.0080221 1.00377 6.94550 5.94173 1363935 1446569_at chr13:115886164-115886710 13 D2.2 IPA Unknown 1076.8741 879.3519 952.5834 189.5512 156.4297 251.6615 0.0027656182 2.30583 9.91621 7.61039 1363963 1446598_at 11 UGA Mm.441616 Transcribed locus 205.4459 171.2456 153.8627 73.4902 48.9827 90.9201 0.021080165 1.34928 7.45601 6.10674 1363986 1446621_at 4 chr4:8740998-8741542 4 A1 UGA Mm.410534 Transcribed locus 376.2577 357.5589 366.0580 94.3405 103.9116 94.5110 6.8249727e-05 1.91070 8.51785 6.60714 1363991 1446626_at 16 B1|16 11.0 cM chr16:18321758-18322258 16 A3 UGA Mm.265990 27883 D16H22S680E DNA segment, Chr 16, human D22S680E, expressed (D16H22S680E), mRNA 72.0407 69.9117 62.5046 34.3475 29.0441 38.7380 0.0050395096 1.00870 6.08803 5.07933 1364283 1446929_at chr4:32333019-32333404 4 A5 IPA Mus musculus 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130062J21 product:hypothetical protein, full insert sequence. 112.8971 108.4463 108.3843 29.7202 48.1468 46.0258 0.022118021 1.44420 6.77990 5.33570 1364301 1446947_at chr2:135743824-135744212 2 F3 IPA Unknown 295.0376 305.6392 295.1431 50.5778 98.3293 61.1347 0.016869838 2.15060 8.22190 6.07130 1364367 1447016_at 5 chr5:64550855-64565499 5 C3.1 RSQ XM_001476849 1 1 100046817 LOC100046817 PREDICTED: hypothetical protein LOC100046817 (LOC100046817), mRNA. 173.5964 195.1596 164.1151 73.2654 84.5402 58.3413 0.0055782734 1.31453 7.46889 6.15436 1364374 1447023_at chr14:18606024-18606518 14 A2 IPA ESTs 71.5846 72.2123 89.0868 36.4919 31.7171 42.3399 0.002657898 1.07742 6.27096 5.19355 1364419 1447071_at chr19:55849331-55849773 19 D2 IPA Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230007B16 product:unknown EST, full insert sequence. 38.5660 36.8253 41.6765 22.5291 19.4489 16.1454 0.010396558 1.02155 5.28435 4.26279 1364442 1447096_at 1 UGA Mm.395135 Transcribed locus 28.9957 55.7832 35.3177 13.7650 12.2680 10.6671 0.017157168 1.66233 5.26728 3.60495 1364676 1447360_at 14 D3|14 42.0 cM chr14:76821285-76821639 14 D3 UGA Mm.153272 21807 Tsc22d1 TSC22-related inducible leucine zipper 1b (Tilz1b) cytoplasm;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 120.0449 117.2486 100.6070 48.2031 40.0111 58.8073 0.0070472051 1.21405 6.81115 5.59710 1364823 1447527_at chr8:47839851-47840054 8 B1.1 IPA ESTs 26.3198 23.8867 23.4200 10.6801 12.4197 12.1738 0.00036005419 1.06292 4.61529 3.55237 1364860 1447575_at chr1:162851522-162851657 1 H2.1 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 462.8211 440.0609 415.9858 169.7343 138.0403 260.0653 0.039186459 1.26582 8.77875 7.51294 1372117 1447830_s_at 1 78.0 cM chr1:145847885-145847980 1 F chr1:145846467-145851279 1 F RSQ Mm.28262 NM_009061 1 1 19735 AL592303.1 Rgs2 regulator of G-protein signaling 2 (Rgs2), mRNA. brown fat cell differentiation;; cell cycle;; G-protein coupled receptor protein signaling pathway;; GTPase activator activity;; negative regulation of signal transduction;; nucleus;; signal transducer activity;; spermatogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle enzyme regulator activity;; molecular transducer activity enzyme activator activity;; nucleoside-triphosphatase regulator activity;; signal transducer activity biological regulation;; cellular process;; developmental process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process cell communication;; cell cycle;; cellular developmental process;; gamete generation;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; reproductive process;; sexual reproduction 1616.6509 1907.4264 1945.8741 306.4852 413.5158 330.5900 0.00026780354 2.38735 10.82747 8.44012 1364970 1447891_at IPA Unknown 226.7805 303.7478 289.4294 83.2405 76.5998 64.7923 0.000467722 1.86424 8.08298 6.21874 1372187 1447937_a_at 4 RSQ Mm.440578 NM_178649 15 15 108816 RP23-388P16.10 4933409K07Rik RIKEN cDNA 4933409K07 gene (4933409K07Rik), mRNA. 285.9852 273.2757 294.7952 131.6773 124.0359 105.2715 0.0030321434 1.24804 8.15253 6.90448 1372188 1447939_a_at 4 RSQ XM_001472444 14 14 100039323 LOC100039323 PREDICTED: similar to 4933409K07Rik protein (LOC100039323), mRNA. 360.5110 306.5686 345.4387 88.6647 110.6624 107.6649 0.00029672239 1.72518 8.39542 6.67024 1365491 1453368_at 11 E2 chr11:120237523-120238045 11 E2 UGA Mm.476851 71885 RP23-82I5.4 2310003H01Rik RIKEN cDNA 2310003H01 gene, mRNA (cDNA clone MGC:37540 IMAGE:4986832) DNA binding;; DNA repair;; nucleus;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding cellular process;; metabolic process;; response to stimulus cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to stress 287.2504 328.2888 282.9922 54.0427 109.4001 110.4763 0.030675681 1.78417 8.22320 6.43903 1365603 1453512_at chr14:120797869-120798366 14 E4 IPA 5430437C10Rik RIKEN cDNA 5430437C10 gene 132.3713 137.5987 131.0525 75.2414 65.5980 58.3114 0.0086361028 1.01734 7.06226 6.04491 1365654 1453586_at 19 C3|19 35.5 cM chr19:40816546-40816931 19 C3 UGA Mm.2824 12495 Entpd1 Ectonucleoside triphosphate diphosphohydrolase 1, mRNA (cDNA clone MGC:18369 IMAGE:3674983) Purine metabolism;; Pyrimidine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] ATP binding;; ATP catabolic process;; basal lamina;; calcium ion binding;; G-protein coupled receptor protein signaling pathway;; hydrolase activity;; integral to membrane;; magnesium ion binding;; membrane;; nucleoside-diphosphatase activity;; nucleoside-triphosphatase activity;; nucleotide binding;; platelet activation;; purine ribonucleoside diphosphate catabolic process cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular matrix part;; extracellular region part;; membrane;; membrane part binding;; catalytic activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus catabolic process;; cell activation;; cell communication;; cellular metabolic process;; coagulation;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; response to external stimulus;; response to stress 67.2531 77.9309 63.2674 31.2060 31.8963 38.5491 0.0014426399 1.03712 6.11301 5.07590 1365738 1453698_at 4 UGA Mm.447147 Transcribed locus 268.2098 250.8772 279.6841 104.7508 103.7209 119.0754 0.00016140708 1.28753 8.05524 6.76770 1366017 1454141_at 10 chr10:69393723-69394253 10 B5.3 chr10:69393067-69394318 10 B5.3 RSQ XM_001474884 2 1 70557 5730416O20Rik PREDICTED: RIKEN cDNA 5730416O20 gene (5730416O20Rik), mRNA. 657.6373 646.6573 650.9016 237.8351 217.2338 239.8541 0.00073312387 1.49379 9.34810 7.85431 1366125 1454295_at 16 chr16:76351867-76352420 16 C3.1 UG5 Mm.453339 Transcribed locus 153.7784 175.3208 197.9001 77.9389 95.8048 87.0499 0.0020091693 1.01237 7.44906 6.43669 1366219 1454397_at 9 chr9:122038549-122039068 9 F4 IPA 4632418H02Rik RIKEN cDNA 4632418H02 gene 181.2528 219.4959 214.4458 60.1656 71.6286 78.3818 0.00054021638 1.55287 7.67479 6.12193 1366240 1454418_at 10 chr10:5322449-5322840 10 A1 UGA Mm.403826 Transcribed locus 379.9297 338.0776 368.4297 68.6281 77.4844 179.4429 0.048232931 1.87737 8.49868 6.62131 1366492 1454768_at 12 chr12:17179290-17179470 12 A1.1 chr12:17178905-17183694 12 A1.1 RSQ Mm.40173 NM_201531 1 1 382571 Kcnf1 potassium voltage-gated channel, subfamily F, member 1 (Kcnf1), mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 524.4297 519.3554 503.9401 270.0684 222.6845 251.7837 0.0043456221 1.06007 9.01076 7.95069 1366823 1455345_at 11 chr11:51626974-51627488 11 B1.3 chr11:51626957-51670983 11 B1.3 RSQ Mm.259996 NM_199299 1 1 76901 RP23-79E13.10 Phf15 PHD finger protein 15 (Phf15), mRNA. metal ion binding;; protein binding;; zinc ion binding binding ion binding;; protein binding 537.8785 522.5164 600.0966 200.6960 225.1912 235.2075 0.0001417812 1.32928 9.10984 7.78056 1366899 1455455_at 3 chr3:85673879-85674282 3 F1 chr3:85673767-85691315 3 F1 RSQ Mm.119926 NM_177130 1 1 320302 Glt28d2 glycosyltransferase 28 domain containing 2 (Glt28d2), mRNA. Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; N-Glycan biosynthesis [PATH:mmu00510];; N-Glycan biosynthesis transferase activity catalytic activity transferase activity 562.7526 486.0086 485.1085 164.8760 115.1972 132.5023 0.0018120566 1.90676 8.99445 7.08769 1367030 1455660_at 15 43.3 cM chr15:78180890-78181373 15 E1 chr15:78156419-78181431 15 E1 RSQ Mm.235324 NM_007780 1 1 12983 Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), mRNA. IL 3 signaling pathway Apoptosis;; Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] cytokine receptor activity;; cytokine-mediated signaling pathway;; integral to membrane;; membrane;; protein binding;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 368.4962 432.4236 366.2865 124.2635 121.3586 151.3185 0.00036232743 1.55893 8.59955 7.04061 1367275 1456160_at 11 UG5 Mm.455208 Transcribed locus 554.0339 506.9572 542.5408 159.9594 135.2528 132.1863 0.00044136042 1.91188 9.06105 7.14917 1372399 1456209_x_at 7 chr7:71051754-71051840 7 C UGA Mm.446212 Transcribed locus 651.0070 597.1829 603.8444 228.6287 247.9022 220.5377 3.7559888e-05 1.41041 9.26886 7.85846 1367413 1456413_at 3 chr3:97569364-97569821 3 F2.2 UGA Mm.443527 Transcribed locus 994.4896 946.4901 946.0183 515.6465 449.6216 471.5172 0.00099741485 1.00867 9.90999 8.90132 1367516 1456610_at 11 chr11:69213540-69214277 11 B3 chr11:69212009-69227177 11 B3 RSQ Mm.261201 NM_001017426 1 1 216850 RP23-5O23.5 Kdm6b KDM1 lysine (K)-specific demethylase 6B (Kdm6b), mRNA. chromatin modification;; histone demethylation;; inflammatory response;; iron ion binding;; metal ion binding;; negative regulation of transcription from RNA polymerase II promoter;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; sequence-specific DNA binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to external stimulus;; response to stress 224.9293 173.6471 179.1942 77.9540 85.6518 114.2956 0.0084401886 1.06571 7.57957 6.51386 1367597 1456761_at 16 chr16:18831001-18831530 16 A3 UGA Mm.440786 Transcribed locus 165.3645 186.3418 180.2684 73.0591 62.1333 88.4579 0.0076383079 1.26337 7.46844 6.20507 1367622 1456789_at 4 chr4:55095838-55096382 4 B3 chr4:54960816-55096435 4 B3 RSQ Mm.102904 NM_172867 1 1 242466 RP23-281K3.2 Zfp462 zinc finger protein 462 (Zfp462), mRNA. negative regulation of DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 428.3287 391.7463 434.3742 207.4813 186.6610 190.9852 7.4838398e-05 1.10024 8.70638 7.60614 1367685 1456854_at 19 C3|19 49.25 cM chr19:47317619-47318055 19 C3 UG5 Mm.313651 18011 Neurl1a Neuralized 1 cytoplasm;; cytoplasm;; lactation;; metal ion binding;; nucleus;; plasma membrane;; protein binding;; response to external stimulus;; sperm axoneme assembly;; sperm motility;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding ion binding;; protein binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; localization;; locomotion;; multicellular organismal process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell motility;; cell motion;; cell projection organization;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; gamete generation;; localization of cell;; microtubule-based process;; multicellular organism reproduction;; multicellular organismal development;; organelle organization;; reproductive process;; reproductive process in a multicellular organism;; response to external stimulus;; sexual reproduction 3018.6502 2920.5796 2704.4297 1090.2856 868.2243 1032.8851 0.0010165665 1.53599 11.49095 9.95496 1367712 1456888_at 9 F2 chr9:108934151-108934674 9 F2 UGA Mm.132391 270198 Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 splice isoform 7 (Pfkfb4) mRNA, complete cds, alternatively spliced Fructose and mannose metabolism CLASS Metabolism; Carbohydrate Metabolism; Fructose and mannose metabolism [PATH:mmu00051] 6-phosphofructo-2-kinase activity;; ATP binding;; catalytic activity;; fructose 2,6-bisphosphate metabolic process;; fructose metabolic process;; fructose-2,6-bisphosphate 2-phosphatase activity;; hydrolase activity;; kinase activity;; metabolic process;; nucleotide binding;; transferase activity binding;; catalytic activity hydrolase activity;; nucleoside binding;; nucleotide binding;; transferase activity metabolic process alcohol metabolic process;; primary metabolic process 1157.7521 1101.0450 1092.7850 428.7722 571.1810 659.5363 0.027631261 1.03613 10.12519 9.08906 1367733 1456909_at 7 B1|7 11.0 cM chr7:35000258-35000824 7 B1 UGA Mm.589 14751 RP23-349I9.4 Gpi1 Glucose phosphate isomerase 1 (Gpi1), mRNA Glycolysis / Gluconeogenesis;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [PATH:mmu00030] Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism [PATH:mmu00500];; Pentose phosphate pathway;; Starch and sucrose metabolism angiogenesis;; cytokine activity;; cytoplasm;; extracellular region;; extracellular space;; gluconeogenesis;; glucose metabolic process;; glucose-6-phosphate isomerase activity;; glucose-6-phosphate isomerase activity;; glycolysis;; growth factor activity;; isomerase activity;; protein binding cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular part binding;; catalytic activity isomerase activity;; protein binding anatomical structure formation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process alcohol metabolic process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; catabolic process;; cellular metabolic process;; multicellular organismal development;; primary metabolic process 266.8480 322.6806 359.8894 66.1316 78.5873 93.3656 0.00051455108 1.99898 8.29508 6.29610 1367751 1456927_at 4 chr4:116008060-116008445 4 D1 UGA Mm.439252 Transcribed locus 357.9297 380.2292 394.9972 152.1946 183.3186 194.6047 0.0042815655 1.10252 8.55999 7.45746 1367806 1456986_at IPA Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430208D19 product:unknown EST, full insert sequence. 18.7084 22.4825 22.8474 9.0663 10.5879 10.0793 0.0010141277 1.10404 4.41010 3.30606 1367837 1457018_at 14 A3 chr14:24240872-24241001 14 A3 UGA Mm.343607 16531 Kcnma1 Calcium-activated potassium channel SLO1 mRNA, complete cds, alternatively spliced Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] adult walking behavior;; apical plasma membrane;; auditory receptor cell differentiation;; binding;; calcium ion binding;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; catalytic activity;; cell maturation;; circadian rhythm;; cytoplasmic part;; endoplasmic reticulum;; external side of plasma membrane;; eye blink reflex;; integral to membrane;; integral to membrane;; ion channel activity;; ion transport;; large conductance calcium-activated potassium channel activity;; large conductance calcium-activated potassium channel activity;; locomotor rhythm;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; micturition;; negative regulation of cell volume;; neuromuscular process controlling balance;; plasma membrane;; postsynaptic membrane;; potassium channel activity;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; protein homooligomerization;; regulation of action potential in neuron;; regulation of aldosterone metabolic process;; regulation of membrane potential;; regulation of membrane potential;; relaxation of vascular smooth muscle;; response to hypoxia;; saliva secretion;; sensory perception of sound;; sensory perception of sound;; smooth muscle contraction involved in micturition;; synaptic transmission;; terminal button;; transport;; vasodilation;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex;; organelle;; synapse;; synapse part apical part of cell;; cell part;; cell projection;; cell projection part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; postsynaptic membrane;; protein complex;; synapse part binding;; catalytic activity;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus;; rhythmic process adult behavior;; anatomical structure development;; behavior;; biosynthetic process;; cell communication;; cellular component assembly;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; circadian rhythm;; developmental maturation;; digestion;; establishment of localization;; hormone metabolic process;; macromolecular complex subunit organization;; multicellular organismal development;; negative regulation of biological process;; negative regulation of multicellular organismal process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress;; rhythmic behavior;; system process;; transport 244.9672 207.5398 230.7607 79.9442 71.9231 88.4681 0.00021876456 1.50918 7.82798 6.31880 1367839 1457022_at chrX:80383845-80383937 X C1 IPA ESTs, Weakly similar to POL2_MOUSE Retrovirus-related POL polyprotein [Contains: Reverse transcriptase ; Endonuclease] [M.musculus] 63.3319 71.8618 77.7923 29.2716 27.5044 34.7240 0.0008569162 1.22090 6.14452 4.92363 1367851 1457035_at 1 chr1:175653611-175655251 1 H3 chr1:175653558-175671940 1 H3 RSQ Mm.440876 XM_980696 3 2 226691 AI607873 PREDICTED: expressed sequence AI607873 (AI607873), mRNA. 38.4873 72.1122 40.8092 19.8031 22.7469 21.0131 0.049020141 1.19361 5.59644 4.40282 1368013 1457206_at 18 chr18:14059095-14059646 18 A1 UG5 Mm.446738 Transcribed locus 170.0468 180.3741 144.4899 73.7131 67.2953 60.8010 0.00057343607 1.29239 7.35982 6.06743 1368059 1457262_at 7 chr7:125276822-125277367 7 F2 chr7:125274825-125387151 7 F2 RSQ Mm.309053 NM_001031814 1 1 233789 Smg1 SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) (Smg1), mRNA. ATP binding;; cytoplasm;; DNA repair;; kinase activity;; manganese ion binding;; metal ion binding;; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;; nucleotide binding;; nucleus;; phosphotransferase activity, alcohol group as acceptor;; protein serine/threonine kinase activity;; response to DNA damage stimulus;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process;; response to stimulus catabolic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to stress 395.4564 401.4318 337.5892 34.1163 50.4593 39.9114 0.00049268288 3.20245 8.55850 5.35606 1368114 1457324_at 4 UGA Mm.444175 Transcribed locus 80.7066 96.7529 102.2285 43.2562 43.9795 48.1622 0.0034467711 1.04103 6.53550 5.49447 1368132 1457342_at 10 chr10:128067933-128068329 10 D3 UGA Mm.441878 Transcribed locus 90.5595 95.8919 103.3047 40.0596 55.5982 44.8582 0.0089993197 1.05552 6.59163 5.53611 1368146 1457357_at 11 E1 chr11:105072019-105072545 11 E1 UGA Mm.126976 24086 RP23-456M3.2 Tlk2 Tousled-like kinase 2 (Arabidopsis) (Tlk2), transcript variant B, mRNA ATP binding;; cell cycle;; cell differentiation;; chromatin modification;; kinase activity;; multicellular organismal development;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; response to DNA damage stimulus;; spermatogenesis;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; reproduction;; reproductive process;; response to stimulus cell cycle;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; multicellular organismal development;; organelle organization;; primary metabolic process;; reproductive process;; response to stress;; sexual reproduction 230.8186 137.4960 128.2968 68.7537 77.4293 75.9167 0.048556462 1.11089 7.31907 6.20817 1368219 1457438_at 4 chr4:11053599-11054027 4 A1 UGA Mm.102270 Transcribed locus 247.2075 244.2311 240.1555 95.2211 95.9989 135.8940 0.019441341 1.18167 7.92984 6.74816 1368238 1457458_at 7 A2 chr7:16987911-16988281 7 A2 UGA Mm.333594 330474 Zc3h4 Zinc finger CCCH-type containing 4 (Zc3h4), mRNA metal ion binding;; nucleic acid binding;; zinc ion binding binding ion binding;; nucleic acid binding 523.5302 546.9647 523.2260 226.2160 245.5520 241.0075 5.5592375e-05 1.16145 9.05291 7.89146 1368255 1457477_at 14 chr14:120728076-120728467 14 E4 UGA Mm.412819 Transcribed locus 76.6594 70.6932 68.8587 28.2239 32.8415 34.8775 0.0014396059 1.17631 6.16982 4.99351 1368293 1457515_at chr3:103569718-103570218 3 F2.2 IPA Mus musculus 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430065F18 product:unknown EST, full insert sequence. 332.6064 269.3753 270.7975 93.5864 87.3115 98.2182 0.0007980788 1.63932 8.17741 6.53808 1368327 1457553_at chr2:6739802-6740289 2 A1 IPA Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630035A22 product:unknown EST, full insert sequence. 65.1958 55.4062 53.1068 26.0696 23.8722 30.4157 0.0013012787 1.11374 5.84984 4.73610 1368349 1457575_at 2 chr2:52734850-52735317 2 C1.1 UGA Mm.26187 Transcribed locus 102.3942 183.7006 270.9852 26.6840 28.9007 30.3025 0.022383649 2.58966 7.42709 4.83743 1368500 1457770_at 14 D2 chr14:70711457-70711852 14 D2 UGA Mm.270647 213053 Slc39a14 Solute carrier family 39 (zinc transporter), member 14 (Slc39a14), transcript variant 3, mRNA ferrous iron transmembrane transporter activity;; integral to membrane;; ion transport;; iron ion transport;; membrane;; metal ion transmembrane transporter activity;; metal ion transport;; plasma membrane;; transport;; zinc ion binding;; zinc ion transmembrane transporter activity;; zinc ion transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 145.3964 140.6163 155.7489 73.8853 45.8964 84.8610 0.046751884 1.15600 7.20085 6.04485 1368595 1457877_at 10 chr10:5471012-5471471 10 A1 UGA Mm.445735 Transcribed locus 158.9917 133.7443 140.6477 75.1392 71.6982 61.2466 0.00092676381 1.06006 7.17069 6.11064 1368617 1457901_at chr4:136909787-136910353 4 D3 IPA ESTs, Weakly similar to S57243 collagen alpha 1(I) chain precursor - mouse [M.musculus] 683.1545 592.0586 642.3201 179.5045 222.8387 231.4087 0.001081495 1.60359 9.31760 7.71401 1368639 1457924_at 3 chr3:60305173-60433670 3 D RSQ Mm.255723 NM_020007 2 2 56758 Mbnl1 muscleblind-like 1 (Drosophila) (Mbnl1), mRNA. cytoplasm;; metal ion binding;; mRNA splice site selection;; nucleic acid binding;; nucleus;; nucleus;; regulation of alternative nuclear mRNA splicing, via spliceosome;; RNA binding;; skeletal muscle tissue development;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; ribonucleoprotein complex biogenesis 345.1150 278.5408 274.5788 50.4674 62.8800 46.2785 0.00016157704 2.49656 8.21792 5.72136 1368796 1458089_at 17 chr17:28572812-28573322 17 A3.3 UGA Mm.445012 Transcribed locus 54.9064 87.2790 88.0691 23.8277 27.9698 35.8988 0.0097036726 1.38027 6.22901 4.84874 1368999 1458308_at 10 C1 chr10:79529116-79529307 10 C1 UG5 Mm.262102 216161 Sbno2 Strawberry notch homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:3376209) macrophage activation during immune response;; negative regulation of transcription, DNA-dependent;; regulation of inflammatory response;; regulation of transcription, DNA-dependent;; transcription;; transcription repressor activity transcription regulator activity transcription repressor activity biological regulation;; cellular process;; immune system process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell activation;; cellular metabolic process;; immune response;; leukocyte activation;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of response to stimulus;; response to external stimulus;; response to stress 826.8973 752.7224 726.8833 237.4021 298.0962 372.0275 0.012646835 1.36768 9.58437 8.21670 1369044 1458376_at 14 chr14:120740319-120740808 14 E4 UGA Mm.440488 Transcribed locus 647.8549 746.7632 809.0697 89.7467 99.4203 90.6606 0.00011015487 2.97283 9.51472 6.54189 1369075 1458409_at chr14:55370840-55371308 14 C3 IPA ESTs 303.4438 289.2736 294.6756 143.5014 133.5125 127.4139 0.00052050539 1.13514 8.20819 7.07304 1369131 1458469_at chr16:52052604-52053123 16 B5 IPA ESTs 165.1664 166.0134 166.9110 84.2446 67.7992 70.8158 0.0065724975 1.16672 7.37529 6.20857 1369180 1458520_at 6 chr6:38689135-38689584 6 B1 UGA Mm.441552 Transcribed locus 196.8989 212.3617 199.0408 91.3111 97.5678 108.4098 0.001268585 1.03574 7.66287 6.62713 1369619 1458969_at chr8:11786297-11786741 8 A1.1 IPA ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 106.0001 103.6980 110.9362 31.8715 36.2455 40.0374 0.0018947676 1.57352 6.73925 5.16573 1369809 1459170_at chr3:52134457-52135011 3 C IPA ESTs 595.7968 588.5269 592.4411 192.4447 271.7739 292.1328 0.021156081 1.25504 9.21006 7.95501 1369874 1459238_at chr10:53062351-53062774 10 B3 IPA ESTs 540.4141 504.3001 515.4086 173.1913 229.7851 282.4886 0.025240515 1.21441 9.02188 7.80747 1370187 1459557_at chr9:48515954-48516379 9 A5.3 IPA ESTs 124.6053 127.1085 137.5409 27.8495 28.7618 56.9326 0.029474393 1.85934 7.01828 5.15895 1370236 1459609_at chr8:79928865-79929131 8 C1 IPA Unknown 70.8882 85.7071 81.8676 26.8483 35.5978 44.5682 0.019575082 1.18187 6.30801 5.12614 1370262 1459635_at IPA ESTs 53.2013 48.4369 41.3416 23.9333 23.5786 23.2114 0.01009484 1.00794 5.56698 4.55904 1370313 1459691_at chr3:30077395-30077749 3 A3 IPA ESTs 78.3820 76.1671 65.1483 32.5642 40.5039 32.2046 0.0018529621 1.06493 6.18973 5.12480 1370414 1459887_at 9 UGA Mm.477617 Transcribed locus 162.6522 164.6721 132.1016 74.4751 55.1390 69.2756 0.0023106376 1.21221 7.25153 6.03932 1372677 1459961_a_at 11 D|11 60.5 cM chr11:100797327-100797529 11 D UGA Mm.249934 20848 RP23-279L23.5 Stat3 Signal transducer and activator of transcription 3, mRNA (cDNA clone IMAGE:3665873) EGF Signaling Pathway;; Erk1/Erk2 Mapk Signaling pathway;; IL 6 signaling pathway;; IL22 Soluble Receptor Signaling Pathway;; PDGF Signaling Pathway;; Role of ERBB2 in Signal Transduction and Oncology;; Signaling of Hepatocyte Growth Factor Receptor;; Stat3 Signaling Pathway;; TPO Signaling Pathway Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200];; Adipocytokine signaling pathway;; Chemokine signaling pathway;; Jak-STAT signaling pathway;; Pancreatic cancer;; Pathways in cancer acute-phase response;; calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; DNA binding;; eating behavior;; eye photoreceptor cell differentiation;; glucose homeostasis;; JAK-STAT cascade involved in growth hormone signaling pathway;; nucleus;; plasma membrane;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; protein dimerization activity;; protein kinase binding;; regulation of multicellular organism growth;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; sexual reproduction;; signal transducer activity;; signal transduction;; temperature homeostasis;; transcription;; transcription activator activity;; transcription factor activity;; transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to endogenous stimulus;; response to external stimulus;; response to stress;; sexual reproduction;; temperature homeostasis 86.6748 84.6133 89.9929 43.6744 44.8343 39.9653 0.00036921956 1.02539 6.44403 5.41864 1370550 1460099_at 18 chr18:81117895-81118449 18 E3 UGA Mm.440050 Transcribed locus