A 1 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen A 2 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen A 3 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen A 4 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen A 5 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen A 6 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen B 7 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen B 8 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen B 9 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen B 10 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen B 11 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen B 12 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen C 13 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen C 14 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen C 15 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen C 16 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen C 17 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen C 18 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Gene Property Filtering 18 arrays and 45101 genes in the input dataset 18 arrays and 144 genes in the output dataset. 44957 genes excluded for Well ID not being in local list 'EG1-test-1+FC'. A A A A A A B B B B B B C C C C C C 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 894.3737 681.8031 743.8286 330.5278 321.1616 366.0845 1366.9234 1288.4973 1228.4832 1235.9096 1431.8894 1165.1646 866.0460 1302.7517 1387.2252 1423.6079 1219.1362 1125.9332 1343142 1415762_x_at 14 chr14:55045788-55048566 14 C2 chr14:55045745-55048587 14 C2 RSQ Mm.248163 NM_026851 1 1 68836 Mrpl52 mitochondrial ribosomal protein L52 (Mrpl52), nuclear gene encoding mitochondrial protein, mRNA. mitochondrion;; ribonucleoprotein complex;; ribosome cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; ribonucleoprotein complex 118.0415 97.9666 141.1925 47.0312 45.6103 70.8538 408.0377 422.6708 480.2979 465.2557 414.5026 476.3741 466.8603 458.5871 502.7127 436.4396 464.1877 377.1207 1327623 1415826_at 1 chr1:5133830-5152217 1 A1 chr1:5073253-5152630 1 A1 RSQ Mm.27082 NM_133826 1 1 108664 Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H (Atp6v1h), mRNA. Lysosome CLASS Metabolism; Energy Metabolism; Oxidative phosphorylation [PATH:mmu00190] Cellular Processes; Transport and Catabolism; Lysosome [PATH:mmu04142];; Metabolic pathways;; Oxidative phosphorylation ATP synthesis coupled proton transport;; binding;; hydrogen ion transmembrane transporter activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; ion transport;; proton transport;; proton-transporting ATPase activity, rotational mechanism;; transport;; vacuolar proton-transporting V-type ATPase, V1 domain cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; protein complex binding;; catalytic activity;; transporter activity hydrolase activity;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; nitrogen compound metabolic process;; primary metabolic process;; transmembrane transport;; transport 5197.8021 6265.2725 3710.5416 715.0791 807.0432 925.9508 7968.0964 7923.0104 7426.4547 7315.9010 7761.3305 7482.8258 4883.6281 6012.6797 5085.4956 4440.4033 4741.5847 4718.4855 1327904 1416203_at 6 27.0 cM chr6:55297961-55298501 6 B3 chr6:55286292-55298549 6 B3 RSQ Mm.18625 NM_007472 1 1 11826 Aqp1 aquaporin 1 (Aqp1), mRNA. integral to membrane;; integral to plasma membrane;; membrane;; transport;; transporter activity;; water channel activity;; water transport cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 115.3201 136.5231 111.6207 68.9065 48.6952 47.7033 84.5784 83.7944 76.8027 76.2812 81.3439 75.8043 100.2623 78.0317 84.4165 85.8974 92.0630 86.8516 1327953 1416263_at 5 chr5:124511877-124512433 5 F chr5:124511865-124545807 5 F RSQ Mm.254839 NM_019875 1 1 56325 Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 (Abcb9), mRNA. ABC transporters;; Lysosome CLASS Environmental Information Processing; Membrane Transport; ABC transporters [PATH:mmu02010] Cellular Processes; Transport and Catabolism; Lysosome [PATH:mmu04142] ATP binding;; ATPase activity;; ATPase activity, coupled to transmembrane movement of substances;; endoplasmic reticulum;; endoplasmic reticulum membrane;; integral to membrane;; lysosome;; membrane;; nucleoside-triphosphatase activity;; nucleotide binding;; peptide transport;; peptide transporter activity;; protein transport;; transport cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity;; transporter activity hydrolase activity;; nucleoside binding;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 474.9331 437.8193 508.9050 236.2890 229.3929 226.8461 1234.2021 1206.4479 1184.3998 1004.3454 1268.9365 1032.3984 1117.3011 803.7350 807.2615 985.8341 1222.4575 1023.0964 1328075 1416424_at 17 chr17:56419037-56419482 17 D chr17:56418384-56429934 17 D RSQ Mm.311696 NM_025836 1 1 66905 M6prbp1 mannose-6-phosphate receptor binding protein 1 (M6prbp1), mRNA. cytoplasm;; endosome;; lipid particle;; membrane;; transport cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle establishment of localization;; localization establishment of localization;; transport 1333.8741 908.7075 838.2501 471.4019 417.3186 532.1970 656.9386 660.2101 480.2473 502.5062 671.6734 516.6473 413.8334 540.0146 521.0069 701.0103 575.5954 377.8358 1328220 1416614_at 2 chr2:125499928-125500353 2 F1 chr2:125498835-125501379 2 F1 RSQ Mm.425101 NM_025613 1 1 58521 RP23-323D9.2 Eid1 EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA. cell cycle;; cell differentiation;; cytoplasm;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; specific transcriptional repressor activity;; transcription;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 710.9394 799.6535 766.4065 263.7303 324.1861 342.8733 609.6279 574.1519 687.8141 623.3034 593.7610 628.7035 855.0174 712.6264 898.9166 978.0375 780.5792 653.3571 1328325 1416740_at 2 18.0 cM chr2:27892524-27893024 2 A3 chr2:27741944-27895030 2 A3 RSQ Mm.7281 NM_015734 1 1 12831 Col5a1 collagen, type V, alpha 1 (Col5a1), mRNA. ECM-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510];; Focal adhesion basement membrane;; blood vessel development;; cell adhesion;; collagen;; collagen;; collagen fibril organization;; collagen fibril organization;; extracellular matrix;; extracellular matrix structural constituent;; extracellular region;; heart morphogenesis;; heparin binding;; platelet-derived growth factor binding;; protein binding;; proteinaceous extracellular matrix;; regulation of cellular component organization;; skin development;; structural molecule activity extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part binding;; structural molecule activity carbohydrate binding;; extracellular matrix structural constituent;; pattern binding;; protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; extracellular structure organization;; multicellular organismal development;; regulation of biological process;; regulation of cellular component organization 304.8989 331.2013 292.3382 140.4448 144.0026 134.7036 186.8497 196.0534 206.8741 208.1918 210.7465 201.2943 283.8112 271.5583 372.2753 433.8378 303.6043 254.9051 1328326 1416741_at 2 18.0 cM chr2:27893657-27894081 2 A3 chr2:27741944-27895030 2 A3 RSQ Mm.7281 NM_015734 1 1 12831 Col5a1 collagen, type V, alpha 1 (Col5a1), mRNA. ECM-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510];; Focal adhesion basement membrane;; blood vessel development;; cell adhesion;; collagen;; collagen;; collagen fibril organization;; collagen fibril organization;; extracellular matrix;; extracellular matrix structural constituent;; extracellular region;; heart morphogenesis;; heparin binding;; platelet-derived growth factor binding;; protein binding;; proteinaceous extracellular matrix;; regulation of cellular component organization;; skin development;; structural molecule activity extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part binding;; structural molecule activity carbohydrate binding;; extracellular matrix structural constituent;; pattern binding;; protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; extracellular structure organization;; multicellular organismal development;; regulation of biological process;; regulation of cellular component organization 186.9819 208.8272 226.0408 67.4182 76.5623 92.6209 306.4065 322.0408 462.7434 452.3175 295.9960 474.3021 225.1327 200.4297 210.4280 227.3950 208.7630 166.9852 1328472 1416926_at 4 chr4:11101005-11101491 4 A1 chr4:11083587-11101524 4 A1 RSQ Mm.393018 NM_021897 1 1 60599 RP23-343F17.4 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Trp53inp1), mRNA. apoptosis;; cell cycle arrest;; cytoplasm;; induction of apoptosis;; nucleolus;; nucleus;; response to stress cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part biological regulation;; cellular process;; death;; developmental process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cell death;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 82.5240 64.7226 80.0977 31.8113 38.4021 40.8662 43.4558 36.1897 28.8217 44.2583 44.1676 45.5305 35.8719 40.7005 34.2760 38.4328 32.8583 33.9503 1343424 1417029_a_at 3 chr3:83994438-83995028 3 F1 chr3:83965795-84024799 3 F1 RSQ Mm.44876 NM_030706 1 1 80890 Trim2 tripartite motif-containing 2 (Trim2), mRNA. cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding 3880.2921 3149.7630 3281.5221 992.5058 480.8116 342.0969 1211.5623 1226.7845 990.0217 999.1666 1134.4149 940.1416 1024.1355 1275.5130 1269.5165 1513.9279 1500.2616 1431.4297 1343489 1417393_a_at 4 83.0 cM chr4:155339985-155340225 4 E2 chr4:155336426-155340738 4 E2 RSQ Mm.29140 NM_026125 1 1 67389 RP23-118E21.2 Fam132a family with sequence similarity 132, member A (Fam132a), mRNA. extracellular region extracellular region 567.1643 412.5620 552.8167 267.2933 214.2065 267.1925 122.2948 132.9574 123.5836 141.9404 123.4142 125.3278 160.9726 169.9192 131.9329 158.3902 142.5408 148.8449 1328921 1417470_at 15 48.6 cM chr15:79737758-79738225 15 E1 chr15:79722837-79738859 15 E1 RSQ Mm.284059 NM_030255 2 1 80287 Apobec3 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 (Apobec3), transcript variant 2, mRNA. Atrazine degradation CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; Atrazine degradation [PATH:mmu00791] cytoplasm;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;; metal ion binding;; nucleus;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; ion binding 987.0104 889.1940 1325.5775 423.5172 393.7615 493.8772 87.1348 78.9849 80.4972 80.5003 83.1528 76.6892 103.7687 84.1436 87.8626 101.2902 89.8428 109.6663 1329049 1417620_at 15 chr15:78391723-78391868 15 E1 chr15:78389598-78403213 15 E1 RSQ Mm.1972 NM_009008 1 1 19354 Rac2 RAS-related C3 botulinum substrate 2 (Rac2), mRNA. Adherens junction;; Axon guidance;; B cell receptor signaling pathway;; Chemokine signaling pathway;; Colorectal cancer;; Fc epsilon RI signaling pathway;; Focal adhesion;; Leukocyte transendothelial migration;; MAPK signaling pathway;; Natural killer cell mediated cytotoxicity;; Pancreatic cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Environmental Information Processing; Signal Transduction; VEGF signaling pathway [PATH:mmu04370] Cellular Processes; Cell Motility; Reg;; Pathways in cancer;; Regulation of actin cytoskeleton;; VEGF signaling pathway;; Wnt signaling pathway actin cytoskeleton organization;; cell projection assembly;; chemotaxis;; cytoplasm;; GTP binding;; GTPase activity;; intracellular;; membrane;; membrane fraction;; nuclear envelope;; nucleotide binding;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; small GTPase mediated signal transduction cell;; cell part;; envelope;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle envelope;; organelle part binding;; catalytic activity hydrolase activity;; nucleotide binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; locomotion;; positive regulation of biological process;; regulation of biological process;; response to stimulus actin filament-based process;; behavior;; cell communication;; cell projection organization;; cell proliferation;; cellular component assembly;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; response to chemical stimulus;; response to external stimulus;; taxis 167.8284 127.9413 218.9329 56.8837 75.3093 98.2152 37.5194 30.8623 44.2120 35.5274 38.5886 37.9825 68.8973 61.9846 75.1407 99.2828 67.8653 49.1963 1329114 1417707_at 5 chr5:151374337-151374777 5 G3 chr5:151374217-151397100 5 G3 RSQ Mm.279932 NM_133898 1 1 100637 N4bp2l1 NEDD4 binding protein 2-like 1 (N4bp2l1), mRNA. 1428.0858 1402.4556 1891.8260 726.2576 650.3101 792.2938 298.4677 293.4308 434.0383 418.2868 274.7395 432.3518 423.0122 679.2372 488.9040 529.0672 427.6506 460.3899 1343629 1418230_a_at 10 30.0 cM chr10:57876749-57884498 10 B4 chr10:57786294-57887437 10 B4 RSQ Mm.57734 NM_026148 1 1 110829 Lims1 LIM and senescent cell antigen-like domains 1 (Lims1), mRNA. cell junction;; cell-cell adhesion;; cell-matrix adhesion;; chordate embryonic development;; establishment or maintenance of cell polarity;; focal adhesion;; membrane;; metal ion binding;; plasma membrane;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding ion binding;; protein binding biological adhesion;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component morphogenesis;; cellular developmental process;; embryonic development;; establishment or maintenance of cell polarity;; multicellular organismal development 646.7364 581.7833 536.0676 325.8478 265.6844 285.7102 124.7726 116.7525 197.3648 179.5765 109.5747 173.3439 235.7384 203.9815 239.0852 250.4006 230.0990 218.2075 1329554 1418231_at 10 30.0 cM chr10:57884819-57885394 10 B4 chr10:57786294-57887437 10 B4 RSQ Mm.57734 NM_026148 1 1 110829 Lims1 LIM and senescent cell antigen-like domains 1 (Lims1), mRNA. cell junction;; cell-cell adhesion;; cell-matrix adhesion;; chordate embryonic development;; establishment or maintenance of cell polarity;; focal adhesion;; membrane;; metal ion binding;; plasma membrane;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding ion binding;; protein binding biological adhesion;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component morphogenesis;; cellular developmental process;; embryonic development;; establishment or maintenance of cell polarity;; multicellular organismal development 254.4581 234.3568 251.4254 128.4042 106.7119 103.1698 5791.3602 5853.0357 6421.9198 6478.1408 5820.2314 6459.9297 5211.1742 4363.7070 5204.7875 4250.3821 5026.2550 4182.4183 1329593 1418288_at 12 9.0 cM chr12:16542905-16543338 12 A1.1 chr12:16542474-16596576 12 A1.1 RSQ Mm.153625 NM_172950 3 1 14245 Lpin1 lipin 1 (Lpin1), transcript variant 1, mRNA. actin cytoskeleton reorganization;; cellular response to insulin stimulus;; lipid metabolic process;; nucleus;; phosphatidate phosphatase activity;; regulation of fat cell differentiation;; ruffle organization cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity biological regulation;; cellular component organization;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; cell projection organization;; cellular developmental process;; cellular response to stimulus;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to chemical stimulus;; response to endogenous stimulus 1847.6018 1633.1047 1687.9715 1028.1117 567.9069 684.2168 1032.8741 1144.3464 769.0611 728.1503 1001.2133 725.6042 843.4669 1074.7625 971.4124 1404.3809 1478.8581 1222.7406 1329631 1418337_at 6 30.0 cM chr6:70715740-70716204 6 C1 chr6:70715713-70742169 6 C1 RSQ Mm.17905 NM_009075 1 1 19895 Rpia ribose 5-phosphate isomerase A (Rpia), mRNA. Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [PATH:mmu00030];; Pentose phosphate pathway isomerase activity;; pentose-phosphate shunt, non-oxidative branch;; ribose-5-phosphate isomerase activity catalytic activity isomerase activity cellular process;; metabolic process alcohol metabolic process;; catabolic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; secondary metabolic process 264.6519 119.1835 180.3065 39.4668 33.0190 54.0981 876.9061 935.5964 877.5204 779.2167 848.3936 875.0477 1073.6792 867.9217 882.9452 933.9178 930.1724 854.0012 1329767 1418497_at X 18.0 cM chrX:56315349-56315904 X A6 chrX:56315321-56387613 X A6 RSQ Mm.7995 NM_010200 1 1 14168 RP23-387L21.1 Fgf13 fibroblast growth factor 13 (Fgf13), mRNA. MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Melanoma [PATH:mmu05218];; Pathways in cancer;; Regulation of actin cytoskeleton cytoplasm;; growth factor activity;; MAPKKK cascade;; nucleus;; protein binding;; protein kinase activator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; enzyme regulator activity enzyme activator activity;; kinase regulator activity;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 1957.3849 2013.6738 2126.5000 1062.8596 767.5999 1215.7655 785.5392 782.2630 1061.4361 990.5499 790.6162 951.0408 488.5663 700.5964 736.8741 572.4142 558.6869 477.3937 1343832 1419291_x_at 1 H2.1 chr1:162965890-162968390 1 H2.1 UGA Mm.270065 14455 Gas5 Growth arrest specific 5, mRNA (cDNA clone IMAGE:3585621) 846.3824 907.2908 1034.4234 563.2901 410.9772 392.7264 43.7447 32.0813 39.4724 39.6995 37.6523 32.9825 40.3427 51.4282 41.9713 30.4458 35.2037 37.7717 1330500 1419402_at 9 chr9:72300512-72304711 9 D chr9:72286341-72306381 9 D RSQ Mm.387671 NM_008613 1 1 17427 Mns1 meiosis-specific nuclear structural protein 1 (Mns1), mRNA. intermediate filament;; meiosis;; nuclear envelope;; nucleus cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle envelope;; organelle part cellular process cell cycle;; cell cycle process 273.7630 203.7476 348.1722 113.7425 116.5800 155.7780 544.3542 576.7994 527.8548 512.2543 572.8632 521.0247 897.2922 661.3186 669.3047 745.5964 843.4882 608.5964 1343908 1419657_a_at 9 chr9:96976020-96976214 9 E3.3 UGA Mm.475433 Transcribed locus 543.6338 486.0079 520.5681 228.5432 165.0291 203.7968 40.6682 40.2852 42.5405 40.7681 46.2701 37.7698 92.8547 71.0206 71.8488 81.2684 70.3014 78.0408 1331572 1420970_at 8 C3|8 40.0 cM UGA Mm.288206 11513 Adcy7 Adenylate cyclase 7 (Adcy7), transcript variant 1, mRNA Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] Cellu;; Purine metabolism;; Vascular smooth muscle contraction activation of adenylate cyclase activity;; adenylate cyclase activity;; ATP binding;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; nucleotide binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 401.3166 360.1335 394.7866 174.6403 164.0325 146.5892 500.3011 519.3696 432.3085 428.8190 496.2075 444.1726 579.7886 519.7890 551.7344 668.2797 630.9297 538.2649 1331658 1421088_at X 16.0 cM chrX:49406278-49406789 X A5 chrX:49406194-49518100 X A5 RSQ Mm.1528 NM_008150 1 1 14735 RP23-309D15.3 Gpc4 glypican 4 (Gpc4), mRNA. anchored to membrane;; extracellular region;; heparan sulfate proteoglycan binding;; membrane;; plasma membrane;; proteinaceous extracellular matrix cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; membrane;; membrane part binding protein binding 567.2075 416.5025 455.4481 220.8392 160.4386 179.7084 140.4297 135.6996 141.3207 145.1010 131.3188 150.5408 104.3776 83.6250 99.3985 117.8407 93.6067 101.6839 1331784 1421268_at 4 B3|4 32.0 cM chr4:59231380-59233391 4 B3 UG5 Mm.198803 22234 RP23-57N22.4 Ugcg UDP-glucose ceramide glucosyltransferase (Ugcg), mRNA Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide glucosyltransferase activity;; endoplasmic reticulum;; integral to membrane;; lipid biosynthetic process;; lipid metabolic process;; membrane;; sphingolipid metabolic process;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 236.6987 171.5430 216.9432 100.2014 71.9338 100.1365 61.5092 65.0088 69.9458 70.6481 58.6980 62.1066 61.3136 51.0052 61.1234 66.0104 61.5915 62.1371 1331785 1421269_at 4 32.0 cM chr4:59233776-59234110 4 B3 chr4:59202421-59235705 4 B3 RSQ Mm.198803 NM_011673 1 1 22234 RP23-57N22.4 Ugcg UDP-glucose ceramide glucosyltransferase (Ugcg), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide glucosyltransferase activity;; endoplasmic reticulum;; integral to membrane;; lipid biosynthetic process;; lipid metabolic process;; membrane;; sphingolipid metabolic process;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 648.1691 380.5887 377.3741 199.9852 138.5261 100.3636 18.6002 17.1193 18.9896 17.3352 19.2484 19.2334 16.7072 20.0155 18.8384 19.7384 16.6118 22.7166 1344316 1421317_x_at 10 16.0 cM chr10:20844735-20880790 10 A3 RSQ Mm.52109 NM_010848 1 1 17863 Myb myeloblastosis oncogene (Myb), mRNA. calcium ion transport;; DNA binding;; embryonic gut development;; G1/S transition of mitotic cell cycle;; in utero embryonic development;; nucleus;; protein binding;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell cycle;; cell cycle process;; cellular metabolic process;; embryonic development;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 193.4643 169.7166 106.9174 99.5596 58.3126 64.9804 35.0751 35.9628 42.1669 39.2368 32.1532 36.4811 28.7071 33.8314 35.0243 28.4654 34.1430 31.3289 1344354 1421457_a_at 16 chr16:75859567-75873738 16 C3.1 chr16:75859038-75909511 16 C3.1 RSQ Mm.131406 NM_023380 1 1 67742 Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 (Samsn1), mRNA. cytoplasm;; phosphotyrosine binding cell;; cell part cell part;; intracellular;; intracellular part binding protein binding 221.8825 251.6971 252.9140 74.4160 80.6535 74.5008 20.5898 21.9765 25.4230 24.2241 18.8022 24.4959 35.1883 28.9067 31.2058 35.3849 32.8845 39.7853 1332272 1421936_at 3 chr3:137596032-137612732 3 G3 chr3:137593969-137644513 3 G3 RSQ Mm.254835 NM_011932 1 1 26377 Dapp1 dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (Dapp1), mRNA. B cell receptor signaling pathway CLASS Cellular Processes; Immune System; B cell receptor signaling pathway [PATH:mmu04662] cytoplasm;; membrane;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; protein binding cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; protein binding 439.1609 463.3741 434.3637 150.4024 146.6434 146.1616 48.8349 47.4742 51.8169 54.0129 51.3905 60.9620 67.0684 55.3333 70.7309 68.3138 66.9678 68.9855 1332273 1421937_at 3 chr3:137594004-137594525 3 G3 chr3:137593969-137644513 3 G3 RSQ Mm.254835 NM_011932 1 1 26377 Dapp1 dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (Dapp1), mRNA. B cell receptor signaling pathway CLASS Cellular Processes; Immune System; B cell receptor signaling pathway [PATH:mmu04662] cytoplasm;; membrane;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; protein binding cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; protein binding 635.4905 612.4653 730.8496 336.1630 242.6866 277.8036 103.0591 118.3932 116.5311 103.6735 122.7998 105.9614 116.4679 114.4313 100.5722 105.9124 112.9841 125.0210 1332316 1422007_at 4 chr4:41040636-41041741 4 A5 chr4:41039756-41045216 4 A5 RSQ Mm.34043 NM_016689 1 1 11828 RP23-28I8.7 Aqp3 aquaporin 3 (Aqp3), mRNA. basolateral plasma membrane;; integral to membrane;; integral to plasma membrane;; membrane;; transport;; transporter activity;; water channel activity;; water transport cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 48.8331 32.8615 54.4905 14.6665 10.6200 12.6983 7.6706 8.6620 8.1927 8.3597 7.3698 7.4366 8.6748 9.2902 8.1361 7.6458 9.2150 7.6215 1344508 1422008_a_at 4 chr4:41040214-41040288 4 A5 UGA Mm.34043 11828 RP23-28I8.7 Aqp3 Aquaporin 3, mRNA (cDNA clone MGC:35966 IMAGE:4951027) basolateral plasma membrane;; integral to membrane;; integral to plasma membrane;; membrane;; transport;; transporter activity;; water channel activity;; water transport cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 211.3471 125.9606 98.2149 31.1925 25.9123 22.3080 11.2946 11.4623 11.5382 12.5040 10.8671 10.6111 11.6227 14.8984 13.6550 15.8573 11.8068 11.8297 1344693 1422734_a_at 10 16.0 cM chr10:20845276-20845822 10 A3 chr10:20844735-20880790 10 A3 RSQ Mm.52109 NM_010848 1 1 17863 Myb myeloblastosis oncogene (Myb), mRNA. calcium ion transport;; DNA binding;; embryonic gut development;; G1/S transition of mitotic cell cycle;; in utero embryonic development;; nucleus;; protein binding;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell cycle;; cell cycle process;; cellular metabolic process;; embryonic development;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 387.8434 392.6048 652.6372 164.1993 162.4652 252.8820 587.2702 627.0421 281.4281 320.4872 634.7980 278.4209 361.6557 207.6187 496.2613 633.7762 831.9966 757.8855 1333142 1423100_at 12 40.0 cM chr12:86817651-86818190 12 D2 chr12:86814850-86818219 12 D2 RSQ Mm.246513 NM_010234 1 1 14281 Fos FBJ osteosarcoma oncogene (Fos), mRNA. B Cell Survival Pathway;; BCR Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; EGF Signaling Pathway;; EPO Signaling Pathway;; Fc Epsilon Receptor I Signaling in Mast Cells;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 3 signaling pathway;; IL 6 signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; Inhibition of Cellular Proliferation by Gleevec;; Insulin Signaling Pathway;; MAPKinase Signaling Pathway;; METS affect on Macrophage Differentiation;; Nerve growth factor pathway (NGF);; Oxidative Stress Induced Gene Expression Via Nrf2;; PDGF Signaling Pathway;; Pertussis toxin-insensitive CCR5 Signaling in Macrophage;; Repression of Pain Sensation by the Transcriptional Regulator DREAM;; Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy;; Signaling Pathway from G-Protein Families;; T Cell Receptor Signaling Pathway;; Toll-Like Receptor Pathway;; TPO Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell B cell receptor signaling pathway;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660] Cellular Processes; Immune System; B cell receptor signaling;; MAPK signaling pathway;; Pathways in cancer;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cellular response to extracellular stimulus;; DNA binding;; nervous system development;; nucleus;; nucleus;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein dimerization activity;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; response to drug;; response to protein stimulus;; sequence-specific DNA binding;; transcription factor activity;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to external stimulus 110.1895 122.7943 153.5161 53.9985 58.3791 65.2511 3851.2575 3763.3230 4100.3396 4175.4638 3917.4368 4155.0795 844.5731 784.3094 934.8195 833.1458 935.9843 662.7492 1333245 1423233_at 16 A2|16 9.0 cM chr16:15888053-15888517 16 A2 UGA Mm.347407 12609 Cebpd CCAAT/enhancer binding protein (C/EBP), delta (Cebpd), mRNA DNA binding;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; promoter binding;; protein binding;; protein dimerization activity;; protein heterodimerization activity;; protein homodimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; specific RNA polymerase II transcription factor activity;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 186.0525 202.3542 282.6106 103.6857 94.1487 98.5148 6547.2469 6460.0236 6163.7922 6046.3250 6381.4083 6109.8621 6258.7006 5968.1801 6837.4771 6335.6403 6026.1421 6318.2553 1333273 1423266_at 4 chr4:154270565-154272671 4 E2 chr4:154270538-154273152 4 E2 RSQ Mm.41868 NM_025582 1 1 66469 RP23-15L19.6 2810405K02Rik RIKEN cDNA 2810405K02 gene (2810405K02Rik), mRNA. cytoplasm;; cytosol;; prostaglandin-F synthase activity cell;; cell part cell part;; intracellular;; intracellular part catalytic activity oxidoreductase activity 1489.5531 1510.5814 2297.1785 617.9298 623.6222 956.5569 1132.5595 1088.2881 914.2003 856.5166 1096.7252 851.0651 585.9465 614.9063 621.7684 606.2693 563.0873 554.7075 1344870 1423622_a_at 3 chr3:65750507-65751656 3 E1 chr3:65750072-65762147 3 E1 RSQ Mm.175612 NM_019937 1 1 56706 Ccnl1 cyclin L1 (Ccnl1), mRNA. nucleus;; regulation of transcription, DNA-dependent;; transcription;; transcription elongation factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 537.1924 402.6533 609.7737 207.0145 221.9700 311.0114 173.0597 179.3727 152.7697 169.4493 178.0921 161.0408 122.6720 128.6610 147.7681 131.8667 117.6192 119.1205 1333665 1423760_at 2 E2|2 56.0 cM chr2:102652746-102653171 2 E2 UGA Mm.423621 12505 RP23-203N8.3 Cd44 CD44 antigen, mRNA (cDNA clone IMAGE:3153835) Adhesion Molecules on Lymphocyte;; Monocyte and its Surface Molecules;; Neutrophil and Its Surface Molecules ECM-receptor interaction;; Hematopoietic cell lineage CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Immune System; Hematopoietic cell lineage [PATH:mmu04640] basolateral plasma membrane;; binding;; branching involved in prostate gland morphogenesis;; branching involved in ureteric bud morphogenesis;; cell adhesion;; cell surface;; external side of plasma membrane;; healing during inflammatory response;; hyaluronic acid binding;; hyaluronic acid binding;; integral to membrane;; membrane;; plasma membrane;; protein binding;; receptor activity cell;; cell part cell part;; cell surface;; membrane;; membrane part binding;; molecular transducer activity carbohydrate binding;; pattern binding;; protein binding;; signal transducer activity biological adhesion;; cellular process;; developmental process;; multicellular organismal process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; multicellular organismal development;; reproductive developmental process;; reproductive process;; response to external stimulus;; response to stress 118.9783 82.0329 103.0473 33.8430 47.7694 47.4742 666.8735 681.2750 685.0184 590.8170 706.1611 589.6309 478.6524 530.3593 667.1519 565.1807 767.6775 613.2075 1345125 1424719_a_at 11 E1|11 64.0 cM chr11:104171721-104183829 11 E1 UGA Mm.1287 17762 RP23-136D4.1 Mapt Strain ILS microtubule binding protein tau Bioactive Peptide Induced Signaling Pathway;; Deregulation of CDK5 in Alzheimers Disease Alzheimer's disease CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Human Diseases; Neurodegenerative Diseases; Alzheimer's disease [PATH:mmu05010];; MAPK signaling pathway axon;; cell projection;; cilium axoneme;; cytoplasm;; cytoskeleton;; membrane;; microtubule;; negative regulation of microtubule depolymerization;; plasma membrane;; protein binding cell;; cell part;; organelle;; organelle part axoneme;; cell part;; cell projection;; cell projection part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process cellular component disassembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; microtubule-based process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process 134.9872 123.2389 180.6048 66.5614 51.2786 99.9953 727.7788 688.5773 688.4563 727.0857 689.1243 697.0838 609.4827 762.0745 653.4413 780.8186 728.5787 725.3733 1345182 1424917_a_at 11 68.0 cM chr11:109438372-109438940 11 E1 chr11:109434834-109472703 11 E1 RSQ Mm.35817 NM_145940 1 1 52639 RP23-465A12.6 Wipi1 WD repeat domain, phosphoinositide interacting 1 (Wipi1), mRNA. autophagy;; cytoplasmic vesicle;; endosome;; Golgi apparatus;; pre-autophagosomal structure;; receptor binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; vesicle binding protein binding cellular process;; metabolic process catabolic process;; cellular metabolic process 814.6936 672.7613 685.0909 335.0626 361.7496 331.9460 112.6036 122.7841 124.9479 133.1463 114.4313 115.8258 126.7471 122.8578 130.8173 130.8743 138.3869 138.3815 1334713 1425145_at 1 20.0 cM chr1:40521793-40522217 1 B chr1:40497472-40522260 1 B RSQ Mm.289824 NM_001025602 1 1 17082 Il1rl1 interleukin 1 receptor-like 1 (Il1rl1), transcript variant 1, mRNA. external side of plasma membrane;; extracellular region;; innate immune response;; integral to membrane;; interleukin-1 receptor activity;; interleukin-33 binding;; interleukin-33 receptor activity;; intrinsic to membrane;; membrane;; negative regulation of I-kappaB kinase/NF-kappaB cascade;; plasma membrane;; protein binding;; receptor activity;; signal transduction;; transmembrane receptor activity cell;; cell part;; extracellular region cell part;; cell surface;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; immune system process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell communication;; immune response;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; response to stress 329.8549 335.1087 273.5279 135.9010 136.8898 99.5126 3388.6676 3444.8077 4022.5398 3771.4575 3456.5312 3947.9297 2489.5327 2049.3706 2349.0731 1901.7658 2336.4525 1947.5069 1345855 1426516_a_at 12 9.0 cM chr12:16543928-16544435 12 A1.1 chr12:16542474-16596576 12 A1.1 RSQ Mm.153625 NM_172950 3 1 14245 Lpin1 lipin 1 (Lpin1), transcript variant 1, mRNA. actin cytoskeleton reorganization;; cellular response to insulin stimulus;; lipid metabolic process;; nucleus;; phosphatidate phosphatase activity;; regulation of fat cell differentiation;; ruffle organization cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity biological regulation;; cellular component organization;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; cell projection organization;; cellular developmental process;; cellular response to stimulus;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to chemical stimulus;; response to endogenous stimulus 1048.1178 1064.0658 1118.6522 531.2042 447.8208 508.3748 422.0293 503.2001 357.1629 326.7121 411.0657 338.4215 343.7297 290.7389 256.0567 352.5938 341.7421 303.0251 1335678 1426810_at 6 chr6:71539185-71539602 6 C1 chr6:71538965-71582899 6 C1 RSQ Mm.260479 NM_001038695 2 1 104263 Kdm3a lysine (K)-specific demethylase 3A (Kdm3a), transcript variant 2, mRNA. cell differentiation;; chromatin modification;; cytoplasm;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; regulation of transcription, DNA-dependent;; spermatogenesis;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; reproduction;; reproductive process biosynthetic process;; cellular developmental process;; cellular metabolic process;; gamete generation;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; reproductive process;; sexual reproduction 320.1054 390.1330 1325.4994 105.6479 65.3172 153.0859 419.5742 424.9735 221.3057 211.9590 411.8292 228.5464 1545.2201 230.8825 1711.1290 1135.2122 3782.1629 564.7836 1335932 1427126_at 17 B1|17 18.9 cM chr17:35093594-35093973 17 B1 UG5 Mm.372314 15511 Hspa1b Heat shock protein (hsp68) mRNA, clone MHS214 Antigen processing and presentation CLASS Environmental Information Processing; Membrane Transport; Pores ion channels Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Immune System; Antigen processing and presen;; Endocytosis;; MAPK signaling pathway anti-apoptosis;; ATP binding;; DNA repair;; intracellular;; mitochondrial matrix;; mitochondrion;; mitochondrion;; negative regulation of caspase activity;; nucleotide binding;; protein binding;; protein binding;; response to heat;; response to heat;; response to stress;; telomere maintenance cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding nucleoside binding;; nucleotide binding;; protein binding biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell death;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 57.8020 70.0142 82.9677 23.9622 43.3726 27.5418 81.3982 80.8257 133.1210 121.2078 97.1296 108.6982 183.7604 91.1819 95.2436 164.4980 169.6755 83.2559 1335968 1427174_at 2 RSQ Mm.425123 XM_902322 2 2 665211 RP24-87L14.1 OTTMUSG00000016327 PREDICTED: predicted gene, OTTMUSG00000016327, transcript variant 25 (OTTMUSG00000016327), mRNA. metal ion binding;; nucleus;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 1081.0737 1187.8600 1056.0031 305.3604 272.5664 508.4548 69.1066 63.7174 86.2056 72.0950 70.8822 87.6780 74.6225 62.1868 81.8080 72.5435 85.8234 64.1296 1336077 1427305_at X 70.0 cM chrX:160871038-160871470 X F5 chrX:160857718-160871847 X F5 RSQ Mm.3781 NM_011081 1 1 18700 RP23-202H24.3 Piga phosphatidylinositol glycan anchor biosynthesis, class A (Piga), mRNA. Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;; Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis [PATH:mmu00563] biosynthetic process;; endoplasmic reticulum;; GPI anchor biosynthetic process;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; organophosphate metabolic process;; primary metabolic process 2006.7941 1528.9728 1554.1735 857.3377 842.5333 798.8546 201.3741 207.1762 326.4757 323.9433 180.0853 311.0223 110.8906 199.3186 197.3574 119.1336 124.2233 175.8731 1346054 1427334_s_at 6 chr6:149276739-149277084 6 G3 chr6:149257935-149284185 6 G3 RSQ Mm.333515 NM_026054 1 1 67246 RP23-214L4.1 2810474O19Rik RIKEN cDNA 2810474O19 gene (2810474O19Rik), mRNA. 2943.7917 2610.3710 2667.1327 992.6562 869.3799 853.6598 301.8871 271.7504 312.3592 287.0246 298.5785 284.6612 430.1338 423.5813 489.1044 404.7018 371.3341 312.7488 1336585 1428082_at 19 chr19:55368693-55371084 19 D2 chr19:55327858-55371118 19 D2 RSQ Mm.292056 NM_027976 1 1 433256 Acsl5 acyl-CoA synthetase long-chain family member 5 (Acsl5), mRNA. Adipocytokine signaling pathway CLASS Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:mmu00071] Environmental Information Processing; Membrane Transport; Other transporters Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320];; Fatty acid metabolism;; Metabolic pathways;; PPAR signaling pathway ATP binding;; catalytic activity;; endoplasmic reticulum;; fatty acid metabolic process;; integral to membrane;; ligase activity;; lipid metabolic process;; long-chain-fatty-acid-CoA ligase activity;; magnesium ion binding;; membrane;; metabolic process;; microsome;; mitochondrial inner membrane;; mitochondrial outer membrane;; mitochondrion;; nucleotide binding;; peroxisome cell;; cell part;; envelope;; organelle;; organelle part cell fraction;; cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; catalytic activity ion binding;; ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process cellular metabolic process;; primary metabolic process 954.2037 1324.8220 1285.9721 448.8946 532.9185 484.0300 11715.2630 11661.4105 12825.5648 13072.2196 11856.3259 13022.5885 8921.8985 7563.8143 9331.8012 7432.6564 7902.7380 6512.9297 1336586 1428083_at 19 chr19:5842571-5842881 19 A chr19:5842301-5845478 19 A RSQ NR_003513 1 1 66961 2310043N10Rik RIKEN cDNA 2310043N10 gene (2310043N10Rik), non-coding RNA. cellular component maintenance;; cellular component maintenance;; paraspeckles;; protein binding cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding protein binding cellular component organization cellular component maintenance 860.0960 686.3186 990.4852 390.9944 337.9034 468.1144 2097.5808 2097.9821 1959.7337 2014.8186 2048.9397 1902.8452 2014.6663 2579.2630 2553.2679 2614.9492 2645.3943 2566.0830 1346539 1430522_a_at 6 chr6:72319064-72320308 6 C1 IPA Mm.42184 Vamp5 Transcribed locus 54.6452 43.9300 69.7977 17.0753 30.8577 23.9333 13.3295 16.2103 21.1020 14.0461 12.8200 17.7681 16.0033 11.4338 13.4306 13.4306 13.5341 14.3356 1346596 1431024_a_at 13 8.0 cM chr13:14156058-14291870 13 A1 RSQ Mm.439784 NM_198122 2 1 94246 RP23-332P8.1 Arid4b AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 2, mRNA. chromatin;; chromatin assembly or disassembly;; chromatin binding;; DNA binding;; intracellular;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 98.4592 118.7041 102.3332 49.4220 45.1328 46.6040 22.9907 25.7595 28.5353 26.9145 24.6237 23.0613 40.9601 40.3267 34.8730 44.0563 40.2026 27.4980 1337078 1431031_at 13 8.0 cM chr13:14287596-14290148 13 A1 chr13:14156058-14291870 13 A1 RSQ Mm.439784 NM_198122 2 1 94246 RP23-332P8.1 Arid4b AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 2, mRNA. chromatin;; chromatin assembly or disassembly;; chromatin binding;; DNA binding;; intracellular;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 323.6422 524.8182 553.9008 86.4880 104.6569 59.1237 47.7936 54.0663 55.1894 60.4347 45.0097 53.7118 55.4963 48.4026 57.1980 58.2837 53.6430 54.2914 1346678 1431591_s_at 17 chr17:46543911-46544440 17 C chr17:46543871-46544524 17 C RSQ Mm.460266 XR_005074 2 1 677168 LOC677168 PREDICTED: similar to ISG15 ubiquitin-like modifier (LOC677168), misc RNA. 3745.3357 3877.3524 3957.9849 1607.2075 1164.8137 2113.9588 314.9876 300.3467 354.9774 328.8318 280.0321 340.1580 606.3516 529.8788 698.4297 846.0903 625.1551 515.1727 1346686 1431609_a_at 9 6.0 cM chr9:21931170-21935042 9 A3 RSQ Mm.46354 NM_007388 3 1 11433 Acp5 acid phosphatase 5, tartrate resistant (Acp5), transcript variant 3, mRNA. gamma-Hexachlorocyclohexane degradation;; Lysosome CLASS Metabolism; Metabolism of Cofactors and Vitamins; Riboflavin metabolism [PATH:mmu00740] Metabolism; Xenobiotics Biodegradation and Metabolism; gamma-Hexachlorocyclohexane degradation [PATH:mmu00361] Cellular Processes; Transport and Catabolism; Lysosome [PATH:mmu04142];; Riboflavin metabolism acid phosphatase activity;; acid phosphatase activity;; bone morphogenesis;; bone resorption;; dephosphorylation;; hydrolase activity;; immune response;; iron ion binding;; lysosome;; metal ion binding;; response to cytokine stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; ion binding biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; cellular metabolic process;; immune response;; multicellular organismal development;; multicellular organismal homeostasis;; regulation of biological quality;; response to chemical stimulus;; tissue remodeling 514.9806 435.9297 544.6393 122.8451 152.9768 143.7075 225.0617 216.6719 226.4444 220.0836 233.1767 214.3961 280.5707 264.2046 275.5756 313.3419 268.3983 232.2220 1337310 1433645_at 4 chr4:53580183-53580557 4 B2 UGA Mm.439778 Transcribed locus 533.1236 498.7580 495.8090 226.2112 195.2836 299.8937 256.3815 275.4010 298.1364 291.2075 233.4710 269.0880 498.0894 380.2200 499.9199 396.3056 362.7243 285.7825 1337328 1433702_at 19 24.5 cM chr19:29684716-29685256 19 C1 chr19:29684372-29722910 19 C1 RSQ Mm.267131 NM_001081213 1 1 226090 Ermp1 endoplasmic reticulum metallopeptidase 1 (Ermp1), mRNA. endoplasmic reticulum;; hydrolase activity;; integral to membrane;; membrane;; metal ion binding;; metallopeptidase activity;; peptidase activity;; proteolysis;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; ion binding metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 715.5254 570.1265 779.6214 235.4655 160.2075 318.7869 37.1989 23.6189 31.2438 30.4635 30.7068 32.4115 45.3630 42.3494 44.7437 60.2449 38.6386 35.9040 1346988 1433963_a_at 19 A chr19:7073992-7074179 19 A UGA Mm.157591 108101 Fermt3 Fermitin family homolog 3 (Drosophila) (Fermt3), mRNA cell adhesion;; cytoplasm;; podosome;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding protein binding biological adhesion;; cellular process cell adhesion 320.6442 269.2096 397.3526 144.5408 161.2668 144.3783 325.7237 346.4376 253.7119 229.4297 304.2356 227.2895 294.9233 363.0096 284.9112 346.7309 322.3114 309.1707 1337527 1434403_at 11 A3.2 chr11:19923448-19923876 11 A3.1 UGA Mm.266627 114716 Spred2 Sprouty-related, EVH1 domain containing 2, mRNA (cDNA clone IMAGE:4946146) Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] cytoplasm;; cytoplasmic vesicle;; inactivation of MAPK activity;; membrane;; multicellular organismal development;; plasma membrane;; protein binding;; regulation of signal transduction;; stem cell factor receptor binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; vesicle binding protein binding biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process cell communication;; cellular metabolic process;; multicellular organismal development;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 587.0310 702.0435 556.7547 248.3423 251.1971 237.7585 494.0163 487.6101 541.7781 485.3066 511.0496 509.3687 649.7479 618.9255 730.9304 882.1653 655.2621 499.5933 1337545 1434479_at 2 18.0 cM chr2:27894229-27894647 2 A3 chr2:27741944-27895030 2 A3 RSQ Mm.7281 NM_015734 1 1 12831 Col5a1 collagen, type V, alpha 1 (Col5a1), mRNA. ECM-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510];; Focal adhesion basement membrane;; blood vessel development;; cell adhesion;; collagen;; collagen;; collagen fibril organization;; collagen fibril organization;; extracellular matrix;; extracellular matrix structural constituent;; extracellular region;; heart morphogenesis;; heparin binding;; platelet-derived growth factor binding;; protein binding;; proteinaceous extracellular matrix;; regulation of cellular component organization;; skin development;; structural molecule activity extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part binding;; structural molecule activity carbohydrate binding;; extracellular matrix structural constituent;; pattern binding;; protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; extracellular structure organization;; multicellular organismal development;; regulation of biological process;; regulation of cellular component organization 310.8061 223.3808 240.1549 76.6587 61.5777 76.0679 113.9845 122.9288 127.7652 105.7491 123.8753 112.0921 104.4733 95.9989 111.0214 117.2671 102.9962 90.5771 1337731 1435133_at 4 32.0 cM chr4:59235031-59235321 4 B3 chr4:59202421-59235705 4 B3 RSQ Mm.198803 NM_011673 1 1 22234 RP23-57N22.4 Ugcg UDP-glucose ceramide glucosyltransferase (Ugcg), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide glucosyltransferase activity;; endoplasmic reticulum;; integral to membrane;; lipid biosynthetic process;; lipid metabolic process;; membrane;; sphingolipid metabolic process;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 448.7828 495.8684 511.7260 241.1061 235.9402 229.6298 246.0212 252.8326 260.7341 224.3507 231.2093 232.3444 318.0964 280.8400 317.9194 303.0654 304.2410 267.7148 1337863 1435768_at 13 8.0 cM chr13:14291062-14291384 13 A1 chr13:14156058-14291870 13 A1 RSQ Mm.439784 NM_198122 2 1 94246 RP23-332P8.1 Arid4b AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 2, mRNA. chromatin;; chromatin assembly or disassembly;; chromatin binding;; DNA binding;; intracellular;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 520.8849 642.5018 738.9405 237.4599 251.9093 369.4487 299.9802 282.8327 294.0347 295.4852 280.8741 302.0470 238.7624 335.2522 411.1338 389.3035 362.8427 344.0422 1347257 1435866_s_at 11 chr11:58768640-58769076 11 B1.3 UGA Mm.212549 319162 RP23-441I8.12 Hist3h2a Histone cluster 3, H2a, mRNA (cDNA clone MGC:70265 IMAGE:6493838) Systemic lupus erythematosus CLASS Human Diseases; Immune Disorders; Systemic lupus erythematosus [PATH:mmu05322] chromosome;; DNA binding;; metal ion binding;; nucleosome;; nucleosome assembly;; nucleus;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein-DNA complex binding ion binding;; nucleic acid binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process cellular component assembly;; cellular macromolecular complex subunit organization;; DNA packaging;; macromolecular complex subunit organization;; organelle organization 378.0301 299.8043 365.2936 179.7303 135.8746 188.7075 283.3922 305.1505 321.8061 311.6191 296.9258 296.2075 306.7996 294.1599 323.2485 351.0015 331.6351 293.4852 1337985 1436427_at 13 A5 chr13:34997342-34997741 13 A3.3 UGA Mm.10027 19134 Prpf4b PRP4 pre-mRNA processing factor 4 homolog B (yeast) (Prpf4b), mRNA ATP binding;; chromosome;; kinase activity;; mRNA processing;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; RNA splicing;; spliceosomal complex;; transferase activity cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 1416.2167 1231.9908 1381.8844 636.3716 517.6806 699.2281 924.8764 942.5325 792.1350 760.7612 918.5652 754.9080 1044.1420 917.7571 1128.2630 1179.9182 1026.7990 927.7244 1338178 1437626_at 17 chr17:84583663-84584242 17 E4 chr17:84583263-84587287 17 E4 RSQ Mm.259321 NM_001001806 1 1 12193 Zfp36l2 zinc finger protein 36, C3H type-like 2 (Zfp36l2), mRNA. cytoplasm;; DNA binding;; metal ion binding;; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;; nucleic acid binding;; nucleus;; regulation of mRNA stability;; RNA binding;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 882.5315 907.6699 1246.2818 676.4264 398.5976 422.6657 801.1346 801.5964 687.1046 754.8259 828.4686 726.4281 614.5818 651.2474 668.6646 685.5362 737.2637 745.5502 1347646 1437708_x_at 4 chr4:150421423-150421502 4 E2 chr4:150421413-150432062 4 E2 RSQ Mm.273930 NM_009498 1 1 22319 RP23-455G15.3 Vamp3 vesicle-associated membrane protein 3 (Vamp3), mRNA. SNARE interactions in vesicular transport CLASS Genetic Information Processing; Folding, Sorting and Degradation; SNARE interactions in vesicular transport [PATH:mmu04130] calcium ion-dependent exocytosis;; cell junction;; integral to membrane;; membrane;; synapse;; synaptosome;; vesicle-mediated transport cell;; cell part;; synapse cell fraction;; cell part;; membrane;; membrane part cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; secretion by cell;; transport;; vesicle-mediated transport 296.3937 229.2207 302.7630 161.5506 143.8065 95.0634 264.3966 250.3935 372.1114 321.0524 240.4852 345.0408 216.3203 298.3718 237.8964 266.2714 267.4815 245.4852 1347729 1438050_x_at IPA Unknown 1053.3186 893.7914 1095.6847 438.6933 349.6322 551.1803 64.9681 74.1900 70.1062 57.6303 75.1488 62.1011 77.1111 70.8576 83.5219 99.8038 100.2268 78.1656 1347952 1438941_x_at 3 F2.3|3 50.4 cM chr3:107876998-107877044 3 F2.3 UGA Mm.274335 109674 RP23-89M15.1 Ampd2 Adenosine monophosphate deaminase 2 (isoform L) (Ampd2), mRNA Metabolic pathways CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230];; Purine metabolism AMP deaminase activity;; deaminase activity;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;; nucleotide metabolic process;; purine base metabolic process;; purine ribonucleoside monophosphate biosynthetic process catalytic activity deaminase activity;; hydrolase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process 641.5439 418.6210 390.4853 130.7576 56.8284 40.8791 245.2212 224.3723 188.8377 159.5010 215.3012 161.7970 152.5283 220.2236 226.0102 275.2413 242.2075 198.8627 1348076 1439422_a_at 4 83.0 cM chr4:155340587-155340725 4 E2 chr4:155336426-155340738 4 E2 RSQ Mm.29140 NM_026125 1 1 67389 RP23-118E21.2 Fam132a family with sequence similarity 132, member A (Fam132a), mRNA. extracellular region extracellular region 258.9306 348.8937 538.4861 128.1594 195.9634 79.7109 11577.5201 12051.4440 10877.0901 11329.7802 11673.7634 11594.6220 11673.0636 10552.7363 11001.1557 11187.3384 10866.1703 11023.7872 1338727 1448154_at 14 chr14:52525190-52525539 14 C2 chr14:52524945-52533163 14 C2 RSQ Mm.26722 NM_001145959 2 1 29811 Ndrg2 N-myc downstream regulated gene 2 (Ndrg2), transcript variant 2, mRNA. cell differentiation;; cytoplasm;; multicellular organismal development;; nervous system development cell;; cell part cell part;; intracellular;; intracellular part cellular process;; developmental process;; multicellular organismal process anatomical structure development;; cellular developmental process;; multicellular organismal development 445.6519 418.9098 389.8159 188.8092 166.6100 251.5820 445.0913 467.9621 338.4312 387.3806 486.6013 395.2075 361.1379 460.9353 436.1008 596.2700 569.5057 362.3703 1348220 1448405_a_at 2 chr2:125500344-125500511 2 F1 chr2:125498835-125501379 2 F1 RSQ Mm.425101 NM_025613 1 1 58521 RP23-323D9.2 Eid1 EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA. cell cycle;; cell differentiation;; cytoplasm;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; specific transcriptional repressor activity;; transcription;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 148.9850 87.5462 162.5718 62.0618 48.9143 58.0702 51.2725 51.8041 49.8515 52.4216 41.9544 48.1395 62.3812 46.6406 49.9731 43.6585 53.4576 42.9069 1348250 1448551_a_at 3 F1 chr3:83968543-83969096 3 F1 UGA Mm.44876 80890 Trim2 Tripartite motif-containing 2 (Trim2), mRNA cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding 990.7310 634.6792 713.0229 394.8213 389.0408 340.8099 1386.3140 1328.0344 1171.5228 1165.4362 1343.1058 1152.6964 1153.6087 1255.3321 1217.4681 1234.3489 1348.4832 1334.8601 1339039 1448559_at 17 chr17:35967612-35969691 17 B1 chr17:35960301-35969732 17 B1 RSQ Mm.2931 NM_008027 1 1 14251 Flot1 flotillin 1 (Flot1), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] flotillin complex;; membrane;; membrane raft;; plasma membrane;; protein binding cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding protein binding 2509.7935 2099.2312 2280.7145 910.4316 618.3510 432.6919 729.0785 783.5408 639.9630 657.2369 732.4852 657.4392 782.2515 830.2134 791.5207 943.3953 1057.0321 978.4566 1339145 1448687_at 4 83.0 cM chr4:155339161-155340205 4 E2 chr4:155336426-155340738 4 E2 RSQ Mm.29140 NM_026125 1 1 67389 RP23-118E21.2 Fam132a family with sequence similarity 132, member A (Fam132a), mRNA. extracellular region extracellular region 1950.8697 1780.4447 1997.9034 785.4732 713.6716 998.4731 1013.3512 1005.9218 1409.0482 1343.1077 1015.7914 1273.0107 664.7391 1024.3075 1015.0386 883.4420 804.0207 766.4312 1348398 1449410_a_at 1 chr1:162965889-162966351 1 H2.1 chr1:162964558-162967458 1 H2.1 RSQ XM_001479454 1 1 100048067 LOC100048067 PREDICTED: hypothetical protein LOC100048067 (LOC100048067), mRNA. 1194.4071 861.3918 914.9395 476.5737 367.5408 322.1530 100.2600 94.8244 59.9717 58.7340 86.5221 64.1202 146.6837 133.7965 128.3416 161.4045 130.5110 122.5946 1340027 1449839_at 8 B1.1|8 26.0 cM chr8:47724466-47724986 8 B1.1 UGA Mm.34405 12367 Casp3 Caspase 3, mRNA (cDNA clone MGC:46907 IMAGE:4482368) Apoptotic DNA fragmentation and tissue homeostasis;; Apoptotic Signaling in Response to DNA Damage;; B Cell Survival Pathway;; Caspase Cascade in Apoptosis;; D4-GDI Signaling Pathway;; FAS signaling pathway ( CD95 );; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Role of Mitochondria in Apoptotic Signaling;; Stress Induction of HSP Regulation;; TNFR1 Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Alzheimer's disease;; Amyotrophic lateral sclerosis (ALS);; Apoptosis;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:;; Huntington's disease;; MAPK signaling pathway;; Natural killer cell mediated cytotoxicity;; p53 signaling pathway;; Parkinson's disease;; Pathways in cancer apoptosis;; apoptosis;; apoptosis;; B cell homeostasis;; cell fate commitment;; cyclin-dependent protein kinase inhibitor activity;; cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; cytoplasm;; DNA fragmentation involved in apoptosis;; heart development;; hydrolase activity;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis by oxidative stress;; induction of apoptosis via death domain receptors;; keratinocyte differentiation;; negative regulation of activated T cell proliferation;; negative regulation of apoptosis;; negative regulation of B cell proliferation;; negative regulation of cell cycle;; negative regulation of cyclin-dependent protein kinase activity;; neuron apoptosis;; peptidase activity;; peptidase activity;; peptidase activity;; peptidase activity;; proteolysis;; release of cytochrome c from mitochondria;; response to DNA damage stimulus;; response to UV;; response to UV;; response to wounding;; sensory perception of sound;; T cell homeostasis cell;; cell part cell part;; intracellular;; intracellular part catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; hydrolase activity;; kinase regulator activity biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell activation;; cell cycle;; cell death;; cell proliferation;; cellular component disassembly;; cellular developmental process;; cellular metabolic process;; leukocyte activation;; leukocyte homeostasis;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of immune system process;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to external stimulus;; response to stress;; system process 1419.3027 1529.1180 1277.5545 551.9725 476.7106 905.6766 144.6236 135.2888 129.9974 141.4028 164.6813 161.5652 220.1250 198.6377 200.2250 201.8457 203.3801 204.8700 1340165 1450036_at 1 7.5 cM chr1:9889360-9889831 1 A2 chr1:9838361-9892651 1 A2 RSQ Mm.336410 NM_001037759 3 1 170755 Sgk3 serum/glucocorticoid regulated kinase 3 (Sgk3), transcript variant 3, mRNA. anti-apoptosis;; ATP binding;; cell communication;; cytoplasmic membrane-bounded vesicle;; cytoplasmic vesicle;; endosome;; kinase activity;; nucleotide binding;; phosphoinositide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; vesicle binding;; catalytic activity lipid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process cell communication;; cell death;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process 105.7091 79.8201 102.1115 41.6861 43.0829 35.1840 230.7630 242.3235 167.7622 180.9728 241.0001 191.8741 414.8807 401.2452 324.6121 520.1367 550.0026 458.3301 1340171 1450044_at 1 30.1 cM chr1:59543258-59543780 1 C1.3 chr1:59538990-59543799 1 C1.3 RSQ Mm.297906 NM_008057 1 1 14369 Fzd7 frizzled homolog 7 (Drosophila) (Fzd7), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Endocrine System; Melanogenesis [PATH:mmu04916] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210] Human Diseases; Cancers; Basal cell carcinom;; Colorectal cancer;; Melanogenesis;; Pathways in cancer;; Wnt signaling pathway cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; receptor activity;; signal transducer activity;; signal transduction;; transmembrane receptor activity;; Wnt receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 513.4762 356.8073 412.0435 139.1363 78.0887 147.5433 17.5503 17.4648 18.6625 20.5990 21.3868 19.4384 51.5856 40.7220 43.1129 54.3777 41.1417 31.2346 1340189 1450065_at 8 40.0 cM chr8:90853286-90853457 8 C3 chr8:90806890-90853861 8 C3 RSQ Mm.288206 NM_001109756 4 1 11513 Adcy7 adenylate cyclase 7 (Adcy7), transcript variant 4, mRNA. Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] Cellu;; Purine metabolism;; Vascular smooth muscle contraction activation of adenylate cyclase activity;; adenylate cyclase activity;; ATP binding;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; nucleotide binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 420.2349 287.2401 183.1995 82.0775 66.3427 34.5685 10.7774 10.9421 12.0964 11.3114 12.4247 9.7818 10.9125 12.8800 13.2343 12.3959 8.5988 11.4738 1348607 1450194_a_at 10 16.0 cM chr10:20844735-20880790 10 A3 RSQ Mm.52109 NM_010848 1 1 17863 Myb myeloblastosis oncogene (Myb), mRNA. calcium ion transport;; DNA binding;; embryonic gut development;; G1/S transition of mitotic cell cycle;; in utero embryonic development;; nucleus;; protein binding;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell cycle;; cell cycle process;; cellular metabolic process;; embryonic development;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 1532.3930 839.0393 1263.1041 428.2030 331.0115 742.7897 71.2665 59.2468 59.6789 56.7410 58.4072 55.5768 69.7236 76.1696 77.2167 68.1870 72.2722 61.6259 1340752 1450850_at 17 chr17:6943113-6943493 17 A1 chr17:6942479-6987129 17 A1 RSQ Mm.277812 NM_009510 2 2 22350 Ezr ezrin (Ezr), mRNA. Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway;; mCalpain and friends in Cell motility;; uCalpain and friends in Cell spread Leukocyte transendothelial migration;; Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670] apical part of cell;; apical plasma membrane;; binding;; cell projection;; cytoplasm;; cytoskeletal protein binding;; cytoskeleton;; establishment or maintenance of apical/basal cell polarity;; extrinsic to membrane;; membrane;; microtubule basal body;; microvillus;; plasma membrane;; protein binding;; regulation of cell shape;; uropod cell;; cell part;; organelle;; organelle part apical part of cell;; cell part;; cell projection;; cell projection part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle;; organelle part;; trailing edge binding protein binding biological regulation;; cellular component organization;; cellular process;; developmental process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cellular component morphogenesis;; cellular developmental process;; establishment or maintenance of cell polarity;; regulation of biological process;; regulation of biological quality;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process 397.0408 348.4717 412.7643 182.1799 152.4651 215.4584 1130.4769 1055.3589 1093.3813 1079.8872 1108.3711 989.1664 891.6477 1205.0189 1175.1960 1295.6631 1143.2555 1038.1632 1340964 1451130_at 8 chr8:73891950-73892466 8 B3.3 chr8:73891115-73893631 8 B3.3 RSQ Mm.41890 NM_025917 2 1 67023 Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) (Use1), transcript variant 1, mRNA. endoplasmic reticulum;; ER to Golgi vesicle-mediated transport;; integral to membrane;; lysosomal transport;; lysosome;; membrane;; protein binding;; protein catabolic process;; protein transport;; transport;; vesicle-mediated transport cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding protein binding cellular process;; establishment of localization;; localization;; metabolic process catabolic process;; cellular localization;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport;; vesicle-mediated transport 335.2636 308.3645 288.5756 173.4559 168.5799 121.3136 31.9599 34.2981 27.4637 30.5358 26.0826 28.1497 32.3359 28.8972 22.4051 30.5997 29.1234 32.3405 1348888 1451239_a_at 5 F chr5:109099703-109100130 5 F UGA Mm.440571 231583 Slc26a1 Solute carrier family 26 (sulfate transporter), member 1, mRNA (cDNA clone MGC:29387 IMAGE:5055098) chloride transmembrane transporter activity;; chloride transport;; integral to membrane;; membrane;; oxalate transmembrane transporter activity;; oxalate transport;; secondary active sulfate transmembrane transporter activity;; sulfate transmembrane transporter activity;; sulfate transport;; transport;; transporter activity cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 854.1622 662.7476 647.0992 354.6519 322.2114 375.4960 141.2707 149.2577 136.2299 132.5854 160.7181 116.9457 84.4534 68.0265 72.5207 72.0641 71.2836 66.6346 1348987 1451596_a_at 11 E2 chr11:116397391-116397921 11 E2 UG5 Mm.20944 20698 RP23-193A16.4 Sphk1 Sphingosine kinase 1, mRNA (cDNA clone MGC:47288 IMAGE:4221357) Phospholipids as signalling intermediaries Calcium signaling pathway;; Metabolic pathways;; Sphingolipid metabolism;; VEGF signaling pathway CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600] Environmental Information Processing; Signal Transduction; VEGF signaling pathway [PATH:mmu04370] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; ATP binding;; blood vessel development;; brain development;; calmodulin binding;; cytoplasm;; diacylglycerol kinase activity;; DNA binding;; inflammatory response;; kinase activity;; membrane fraction;; negative regulation of apoptosis;; nucleotide binding;; positive regulation of cell proliferation;; positive regulation of fibroblast proliferation;; regulation of interleukin-1 beta production;; soluble fraction;; sphinganine kinase activity;; sphinganine kinase activity;; transferase activity cell;; cell part cell fraction;; cell part;; intracellular;; intracellular part binding;; catalytic activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; cell communication;; cell death;; cell proliferation;; cellular metabolic process;; cytokine production;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; response to external stimulus;; response to stress 167.6685 162.5805 304.7198 93.1551 57.5646 76.3728 737.6570 728.5203 594.0791 626.7500 727.2630 620.3930 900.2618 648.9831 911.7915 790.8652 1086.1261 769.2738 1341586 1452094_at 10 B4 chr10:58834123-58834652 10 B4 UGA Mm.2212 18451 P4ha1 Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide, mRNA (cDNA clone MGC:6332 IMAGE:3484815) Arginine and proline metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] binding;; collagen fibril organization;; endoplasmic reticulum;; iron ion binding;; L-ascorbic acid binding;; metal ion binding;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; peptidyl-proline hydroxylation to 4-hydroxy-L-proline;; procollagen-proline 4-dioxygenase activity;; procollagen-proline 4-dioxygenase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity carboxylic acid binding;; ion binding;; oxidoreductase activity;; vitamin binding cellular component organization;; cellular process;; metabolic process cellular metabolic process;; extracellular structure organization;; macromolecule metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 1218.4299 1057.4810 1276.4309 623.5866 530.5148 544.0062 1674.4130 1643.7142 1557.7490 1391.7634 1626.3191 1403.3323 1423.1882 1219.9407 1157.3578 1652.6943 1403.7571 1170.5816 1349215 1452169_a_at 2 E1 chr2:91772987-91773042 2 E1 UGA Mm.314923 104418 RP23-273F8.4 Dgkz Diacylglycerol kinase zeta, mRNA (cDNA clone IMAGE:2650291) Glycerolipid metabolism;; Glycerophospholipid metabolism;; Metabolic pathways;; Phosphatidylinositol signaling system CLASS Metabolism; Lipid Metabolism; Glycerolipid metabolism [PATH:mmu00561] Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] Environmental Information Processing; Signal Transduction; Phosphatidylinositol signaling system [PATH:mmu04070] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; ATP binding;; cytoplasm;; diacylglycerol binding;; diacylglycerol kinase activity;; enzyme inhibitor activity;; intracellular signaling cascade;; kinase activity;; membrane;; metal ion binding;; negative regulation of Ras protein signal transduction;; nucleotide binding;; nucleus;; plasma membrane;; protein binding;; transferase activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; lipid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process cell communication;; cellular metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 210.1433 265.0625 725.7573 73.2586 58.0682 83.8624 418.3741 426.3839 254.4729 270.7828 458.4297 265.2051 747.6121 202.7259 1093.5974 612.0205 2377.4493 409.2975 1341826 1452388_at 17 18.95 cM chr17:35106735-35106996 17 B1 chr17:35106303-35109101 17 B1 RSQ Mm.6388 NM_010479 1 1 193740 Hspa1a heat shock protein 1A (Hspa1a), mRNA. Antigen processing and presentation;; Endocytosis;; MAPK signaling pathway;; Prion diseases CLASS Environmental Information Processing; Membrane Transport; Pores ion channels Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Immune System; Antigen processing and presentation [PATH:mmu04612 ATP binding;; cytoplasmic part;; DNA repair;; mitochondrion;; nucleotide binding;; protein binding;; response to heat;; response to heat;; response to stress;; telomere maintenance cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleoside binding;; nucleotide binding;; protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; response to stimulus cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological quality;; response to abiotic stimulus;; response to stress 135.5635 127.1453 151.2943 63.2004 63.3539 63.3539 53.0212 56.6528 77.2255 78.4641 55.8188 77.1154 61.0662 55.4071 51.0941 58.2647 47.7000 38.3533 1341834 1452397_at 6 chr6:149277376-149277931 6 G3 chr6:149257935-149284185 6 G3 RSQ Mm.333515 NM_026054 1 1 67246 RP23-214L4.1 2810474O19Rik RIKEN cDNA 2810474O19 gene (2810474O19Rik), mRNA. 337.7188 279.2868 420.5110 153.9726 142.4336 201.9509 83.6138 91.8612 79.7091 101.6290 76.6004 88.6675 126.2081 144.5159 132.3187 179.1726 165.1822 57.0988 1342028 1452730_at 6 chr6:148303568-148303875 6 G3 chr6:148303177-148304120 6 G3 RSQ NR_003634 1 1 66184 Rps4y2 ribosomal protein S4, Y-linked 2 (Rps4y2), non-coding RNA. ribosome cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle;; ribonucleoprotein complex 310.2027 289.3808 296.7781 116.4865 103.8190 184.3741 22.8641 24.1418 23.6074 23.8337 23.0772 23.9098 24.6528 26.1727 23.0951 22.6268 24.2726 21.5777 1349430 1453497_a_at X F3-F4|X 70.0 cM UGA Mm.3781 18700 RP23-202H24.3 Piga Testis mRNA for Pig-a Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;; Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis [PATH:mmu00563] biosynthetic process;; endoplasmic reticulum;; GPI anchor biosynthetic process;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; organophosphate metabolic process;; primary metabolic process 286.0473 277.5740 320.1327 133.7629 112.1019 172.5245 168.7697 170.2868 182.5282 182.4672 169.0998 165.1100 133.5914 142.4749 150.2009 152.2630 124.9327 96.5677 1349719 1455696_a_at 13 A5 chr13:34997770-34997924 13 A3.3 UGA Mm.10027 19134 Prpf4b PRP4 pre-mRNA processing factor 4 homolog B (yeast) (Prpf4b), mRNA ATP binding;; chromosome;; kinase activity;; mRNA processing;; nucleotide binding;; nucleus;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; RNA splicing;; spliceosomal complex;; transferase activity cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; ribonucleoprotein complex binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 310.8119 209.4567 337.1976 109.6739 61.7296 126.8748 21.9667 23.8342 21.1695 23.9272 24.8623 20.8566 25.6166 24.8819 24.7728 22.5898 22.6532 25.2894 1349731 1455787_x_at 19 35.0 cM chr19:32589650-32589828 19 C1 chr19:32560258-32589860 19 C1 RSQ Mm.255116 NM_010799 2 2 17330 Minpp1 multiple inositol polyphosphate histidine phosphatase 1 (Minpp1), mRNA. Inositol phosphate metabolism CLASS Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism [PATH:mmu00562] acid phosphatase activity;; endoplasmic reticulum;; hydrolase activity;; membrane;; multiple inositol-polyphosphate phosphatase activity;; plasma membrane cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle catalytic activity hydrolase activity 1690.7908 1082.6950 1767.2253 553.1027 366.5161 687.0006 78.5091 78.2447 68.1827 75.6443 90.8227 80.4868 128.3955 102.4277 144.9935 133.8736 123.3131 129.3908 1349817 1456014_s_at 19 A chr19:7073508-7073579 19 A UGA Mm.157591 108101 Fermt3 Fermitin family homolog 3 (Drosophila) (Fermt3), mRNA cell adhesion;; cytoplasm;; podosome;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding protein binding biological adhesion;; cellular process cell adhesion 2748.3082 2526.6856 2586.4288 856.0964 578.5492 826.5195 113.9132 116.3885 113.4843 118.5030 133.3723 131.4440 263.8941 203.5964 188.1272 253.1616 249.8998 207.1579 1349897 1456307_s_at 8 40.0 cM chr8:90853611-90853839 8 C3 chr8:90806890-90853861 8 C3 RSQ Mm.288206 NM_001109756 4 1 11513 Adcy7 adenylate cyclase 7 (Adcy7), transcript variant 4, mRNA. Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] Cellu;; Purine metabolism;; Vascular smooth muscle contraction activation of adenylate cyclase activity;; adenylate cyclase activity;; ATP binding;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; nucleotide binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 58.5115 46.4320 51.5738 24.6019 22.1646 30.2453 275.8271 275.8271 211.4664 243.9668 263.3904 275.2035 257.8196 263.1292 275.7232 283.1199 263.4971 188.5115 1342941 1460359_at 7 UGA Mm.413022 Transcribed locus 135.9298 121.5168 166.3105 48.2997 79.7091 65.1169 247.3779 234.2274 186.2689 167.7112 232.8597 196.1477 207.3951 145.3385 154.8606 143.5472 143.8936 142.2373 1350347 1428142_at 16 chr16:22381589-22381942 16 B1 chr16:22381385-22439643 16 B1 RSQ Mm.155708 NM_023794 1 1 104156 Etv5 ets variant gene 5 (Etv5), mRNA. IL12 and Stat4 Dependent Signaling Pathway in Th1 Development DNA binding;; nucleus;; positive regulation of transcription;; regulation of branching involved in mammary gland duct morphogenesis;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription activator activity;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process 308.8293 198.6420 255.9297 116.5593 80.2114 119.3414 125.4726 147.0673 120.6136 106.2830 162.6340 105.0861 110.2541 110.4153 132.3455 137.4298 132.2307 102.9981 1370845 1428773_s_at X chrX:11614483-11615007 X A1.1 chrX:11613862-11657180 X A1.1 RSQ Mm.196328 NM_175045 4 1 71458 RP23-451N14.1 Bcor BCL6 interacting corepressor (Bcor), transcript variant c, mRNA. chromatin modification;; negative regulation of specific transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 163.5697 108.9766 140.4635 52.2572 52.5787 73.2394 160.7170 148.1200 109.3416 130.3753 140.3159 123.1725 147.2862 134.3918 130.1026 139.8516 131.9969 105.5541 1351137 1429438_at X chrX:11614120-11614420 X A1.1 chrX:11613862-11657180 X A1.1 RSQ Mm.196328 NM_175045 1 1 71458 RP23-451N14.1 Bcor BCL6 interacting corepressor (Bcor), transcript variant c, mRNA. chromatin modification;; negative regulation of specific transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 437.7876 673.7873 493.0280 177.9702 159.6184 204.9124 19.9329 22.8981 23.1201 19.4724 20.6064 18.1647 19.3880 23.1523 18.7554 15.5318 20.3674 21.4942 1351325 1429700_at 1 RSQ XM_993996 7 6 73176 3110040M04Rik PREDICTED: RIKEN cDNA 3110040M04 gene (3110040M04Rik), mRNA. 453.7107 502.4492 569.4469 175.2567 175.5736 245.8988 833.8778 829.9136 889.5408 891.5075 809.5309 871.8807 875.7389 816.5501 869.2242 802.9311 799.2384 613.3591 1351378 1429778_at 2 0.5 cM chr2:4942355-4952408 2 A1 chr2:4941687-4984984 2 A1 RSQ Mm.116942 NM_181848 1 1 71648 RP23-379M5.2 Optn optineurin (Optn), mRNA. cellular protein localization;; cytoplasm;; Golgi apparatus;; perinuclear region of cytoplasm;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding cellular process;; localization cellular localization;; macromolecule localization 36.8941 44.6757 36.0518 18.4864 17.3059 16.4661 15.2945 14.9533 16.8498 14.4737 16.1343 15.7121 16.1028 17.9910 16.7966 14.5074 23.2085 13.1281 1351662 1430135_at 8 chr8:87446274-87446713 8 C3 UGA Mm.437155 Transcribed locus, moderately similar to NP_055790.1 microtubule associated serine/threonine kinase 1 [Homo sapiens] 265.1656 371.6527 270.3447 102.0505 124.5364 179.7326 140.3307 121.1372 107.1248 105.5884 122.0261 97.7050 115.7029 124.2573 84.8924 158.4433 165.3186 133.2143 1352068 1430653_at 6 chr6:72325857-72326328 6 C1 UGA Mm.442925 Transcribed locus 229.7664 199.8741 202.2193 44.9238 39.0299 53.0373 93.2993 98.2182 108.6177 122.0040 94.4749 116.9830 117.0494 113.0785 105.1014 125.7686 117.1531 69.6505 1371133 1433453_a_at 2 chr2:103558442-103558563 2 E2 chr2:103406466-103558580 2 E2 RSQ Mm.35850 NM_178890 1 1 99382 RP23-338B23.1 Abtb2 ankyrin repeat and BTB (POZ) domain containing 2 (Abtb2), mRNA. DNA binding;; protein binding binding nucleic acid binding;; protein binding 772.0397 529.5772 903.9852 233.0662 322.2737 443.3588 147.4705 157.9209 144.8075 147.6800 147.3649 158.9927 128.2198 138.2004 173.0104 144.2679 140.9238 125.3406 1354595 1434376_at 2 56.0 cM chr2:102651585-102652133 2 E2 chr2:102651297-102741822 2 E2 RSQ Mm.423621 NM_001039151 3 1 12505 RP23-203N8.3 Cd44 CD44 antigen (Cd44), transcript variant 3, mRNA. Adhesion Molecules on Lymphocyte;; Monocyte and its Surface Molecules;; Neutrophil and Its Surface Molecules ECM-receptor interaction;; Hematopoietic cell lineage CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Immune System; Hematopoietic cell lineage [PATH:mmu04640] basolateral plasma membrane;; binding;; branching involved in prostate gland morphogenesis;; branching involved in ureteric bud morphogenesis;; cell adhesion;; cell surface;; external side of plasma membrane;; healing during inflammatory response;; hyaluronic acid binding;; hyaluronic acid binding;; integral to membrane;; membrane;; plasma membrane;; protein binding;; receptor activity cell;; cell part cell part;; cell surface;; membrane;; membrane part binding;; molecular transducer activity carbohydrate binding;; pattern binding;; protein binding;; signal transducer activity biological adhesion;; cellular process;; developmental process;; multicellular organismal process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; multicellular organismal development;; reproductive developmental process;; reproductive process;; response to external stimulus;; response to stress 452.2405 605.3263 421.3186 237.2232 187.8148 299.1048 165.1987 162.8186 194.5040 175.5363 162.0560 172.1180 188.9948 182.1072 191.1925 190.4890 192.4266 158.8455 1354694 1434571_at 15 chr15:35860439-35860918 15 B3.1 chr15:35301300-35860984 15 B3.1 RSQ Mm.309250 NM_177151 1 1 666173 Vps13b vacuolar protein sorting 13B (yeast) (Vps13b), mRNA. protein transport;; transport establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 341.0024 533.9737 539.4626 164.6627 154.8907 211.0225 881.1183 884.1300 892.4742 932.1667 894.2317 917.9090 770.3643 788.2769 812.5942 739.1343 710.8036 551.4707 1355345 1435679_at 2 0.5 cM chr2:4941710-4942090 2 A1 chr2:4941687-4984984 2 A1 RSQ Mm.116942 NM_181848 1 1 71648 RP23-379M5.2 Optn optineurin (Optn), mRNA. cellular protein localization;; cytoplasm;; Golgi apparatus;; perinuclear region of cytoplasm;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding cellular process;; localization cellular localization;; macromolecule localization 56.7733 89.5919 91.3392 36.7641 26.7931 25.3735 24.4222 23.4927 31.2749 23.7226 27.7011 22.5451 24.2991 24.9861 27.8106 25.6685 33.5002 24.5094 1355587 1436080_at 4 chr4:155584150-155584542 4 E2 UGA Mm.475160 Transcribed locus, strongly similar to XP_001001227.1 PREDICTED: hypothetical protein LOC100382 [Mus musculus] 380.7231 405.1227 267.8587 86.8680 100.7344 137.6041 52.4801 51.2207 53.2002 56.0883 50.7732 51.6736 43.3301 54.2185 49.2452 60.1101 61.9982 48.9572 1355840 1436456_at 13 chr13:113521870-113522039 13 D2.2 chr13:113450983-113523106 13 D2.2 RSQ Mm.259799 NM_178746 1 1 268706 Slc38a9 solute carrier family 38, member 9 (Slc38a9), mRNA. amino acid transport;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; transport cell;; cell part cell part;; membrane;; membrane part binding ion binding cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 148.5756 107.8676 159.5133 54.0451 63.4609 50.3807 281.3976 301.4344 254.0095 227.3812 274.8318 216.0244 297.0964 298.2307 355.1287 394.0090 401.2941 336.1282 1355878 1436514_at X chrX:49404677-49405141 X A5 UGA Mm.276524 Transcribed locus 150.7425 178.3420 136.4269 60.9412 70.8379 96.3849 27.1186 35.1305 33.2305 34.9427 28.1495 35.3375 28.4942 33.7911 31.3894 33.2380 35.6742 37.2742 1356155 1437068_at 13 chr13:105028923-105029332 13 D1 UGA Mm.458617 Transcribed locus 120.1388 174.7075 157.6121 74.1900 61.1869 87.6265 40.2661 46.5044 49.3777 41.4104 42.0606 37.9407 35.5046 52.5388 39.9608 54.5203 43.2689 41.0380 1356732 1438131_at 2 B UGA Mm.4465 30050 RP23-446N16.3 Fbxw2 F-box and WD-40 domain protein 2 (Fbxw2), mRNA cytoplasm;; modification-dependent protein catabolic process;; nucleus;; Wnt receptor signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle biological regulation;; cellular process;; metabolic process;; regulation of biological process catabolic process;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 628.2169 993.4996 520.9752 420.9223 295.7577 222.2493 63.1440 83.4578 82.3954 78.8681 65.5164 71.0985 52.5196 98.7911 45.4696 50.4556 49.0393 62.1503 1356779 1438239_at X chrX:166413417-166413946 X F5 UGA Mm.467605 Clone MEX2B-5 Mid1 mRNA, partial sequence 104.5979 141.6332 190.5663 49.0206 46.1869 91.6517 31.5713 25.1180 30.3643 25.3031 23.3938 29.4121 29.5037 29.7756 29.9935 33.8186 19.3696 26.7089 1356785 1438253_at 5 F chr5:114391796-114392286 5 F UGA Mm.389682 231637 Ssh1 CDNA clone IMAGE:40094316 Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] actin binding;; cytoplasm;; cytoskeleton;; dephosphorylation;; hydrolase activity;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 2012.9567 2259.7471 3506.3149 1227.3173 1175.1636 1247.5885 3901.4761 3649.8794 4277.9809 4136.4033 3746.2944 3965.9137 1110.4075 2269.6519 1874.4027 1571.2688 1956.1642 2204.6712 1357019 1438688_at 17 chr17:23943916-23945484 17 A3.3 chr17:23940153-23961708 17 A3.3 RSQ Mm.5222 NM_175229 2 2 75956 Srrm2 serine/arginine repetitive matrix 2 (Srrm2), mRNA. mRNA processing;; nucleus;; RNA splicing;; spliceosomal complex cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process 51.7517 86.0265 42.6880 27.6689 20.5018 31.3618 22.8627 23.6539 27.1783 24.3463 25.0634 22.2346 19.6133 25.4937 20.2166 26.4268 20.5720 18.0316 1357106 1438821_at 1 chr1:161203268-161203534 1 H1 UGA Mm.451705 Transcribed locus 354.5901 408.1860 409.3771 158.2595 174.1487 205.9121 110.6568 113.7598 107.9577 106.3283 124.4099 110.8772 121.4417 101.3728 100.8035 124.3191 125.0096 99.0272 1357197 1439038_at 14 chr14:56514693-56515204 14 C3 chr14:56503805-56515618 14 C3 RSQ Mm.476874 NM_027143 1 1 219094 9130227C08Rik RIKEN cDNA 9130227C08Rik gene (9130227C08Rik), mRNA. 187.0290 284.5575 157.5681 77.4711 94.4457 129.4327 135.8243 168.4377 112.0986 131.0854 162.7272 152.2347 103.3640 114.8325 118.4863 128.3671 127.1602 110.2316 1357922 1440011_at IPA Mus musculus 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630005I06 product:hypothetical protein, full insert sequence. 44.3061 59.9521 59.9811 16.4472 16.6971 16.4083 21.9765 26.5430 26.3894 22.6681 21.5343 21.8462 24.0200 25.4800 17.7536 19.6978 17.8549 22.4447 1358342 1440475_at 4 chr4:155583587-155584084 4 E2 UGA Mm.475160 Transcribed locus, strongly similar to XP_001001227.1 PREDICTED: hypothetical protein LOC100382 [Mus musculus] 130.4760 197.1797 131.2697 49.4803 64.1967 70.6921 86.4242 91.4862 91.8379 100.3246 76.5068 96.3346 71.1014 68.9672 86.2942 78.8088 83.8748 97.1851 1358669 1440851_at 11 A4 chr11:30829827-30830350 11 A4 IPA 4933407N01Rik RIKEN cDNA 4933407N01 gene 108.3824 142.4853 139.3946 51.5871 45.4475 65.1169 29.5431 29.4619 43.2497 65.0289 34.9778 43.4777 27.8903 28.2631 38.1239 25.1719 26.9076 24.4992 1359935 1442302_at 11 A4|11 16.0 cM chr11:32130715-32131174 11 A4 UGA Mm.263161 268395 RP23-177M10.5 Mpg N-methylpurine-DNA glycosylase, mRNA (cDNA clone MGC:25347 IMAGE:4486938) Base excision repair CLASS Genetic Information Processing; Replication and Repair; Base excision repair [PATH:mmu03410] alkylbase DNA N-glycosylase activity;; alkylbase DNA N-glycosylase activity;; base-excision repair;; DNA binding;; DNA repair;; hydrolase activity;; nucleus;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; nucleic acid binding cellular process;; metabolic process;; response to stimulus cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to stress 207.1520 330.4056 269.0443 141.5652 146.8867 86.8699 16.1790 16.7025 20.0662 15.6662 15.9815 16.5043 17.7752 16.1784 17.5157 17.4671 15.9016 17.5468 1361186 1443657_at 3 F1 chr3:84256798-84257124 3 F1 UG5 Mm.331107 229474 Fhdc1 FH2 domain containing 1, mRNA (cDNA clone MGC:169256 IMAGE:8860651) actin binding;; actin cytoskeleton organization;; cellular component organization binding protein binding cellular component organization;; cellular process actin filament-based process;; organelle organization 95.6014 123.4434 99.1233 38.6592 42.0854 57.3694 45.6747 46.8901 47.4478 45.9194 43.8744 43.8620 52.9847 60.7700 67.2066 89.4827 62.4109 71.5953 1361312 1443858_at 7 chr7:111487361-111487819 7 E3 chr7:111487267-111501863 7 E3 RSQ Mm.425502 NM_175677 2 1 319236 9230105E10Rik RIKEN cDNA 9230105E10 gene (9230105E10Rik), transcript variant 2, mRNA. metal ion binding;; zinc ion binding binding ion binding 196.5135 173.5218 228.2096 91.5577 72.0217 65.8819 9.4143 9.1050 9.0074 10.4197 9.5613 9.3454 9.2164 11.0571 10.1624 10.2888 9.4520 10.8910 1362192 1444769_at 9 D chr9:72309340-72309791 9 D UG5 Mm.14485 21778 Tex9 Testis expressed gene 9 (Tex9), mRNA 121.8986 186.4199 124.4802 53.5648 55.9160 57.2090 38.8184 41.2894 38.5353 42.2161 45.6187 42.7660 33.8052 30.6876 32.7610 32.9098 39.9031 35.6635 1362915 1445517_at IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 30.2979 27.8793 37.0549 13.5617 15.6782 15.9443 18.8968 17.8491 17.8737 16.8081 18.6301 17.2628 17.4839 17.1428 17.0009 19.4435 22.0808 12.4569 1363686 1446318_at IPA Mus musculus 10 days neonate cortex cDNA, RIKEN full-length enriched library, clone:A830082F08 product:unknown EST, full insert sequence. 181.3016 304.1940 171.9883 70.7368 72.5128 140.8928 38.7527 44.5733 45.0170 48.0611 41.9373 44.4517 25.9445 26.9975 34.1707 32.1704 33.8044 24.1879 1364592 1447263_at 10 chr10:93343196-93343491 10 C2 UGA Mm.450117 Transcribed locus 159.1484 242.6474 121.1438 59.0227 78.7714 79.9662 31.9970 34.3864 28.8962 30.6135 32.5959 32.6034 36.0338 31.2353 36.6905 38.9914 41.6600 32.4070 1364657 1447337_at chr3:137633674-137634025 3 G3 IPA ESTs 363.7259 342.0916 376.1519 138.5409 103.7172 189.7630 164.7299 153.8002 166.8062 172.2102 167.8770 142.4095 157.7371 159.6684 151.3779 172.0943 154.7604 134.8516 1372079 1447784_x_at 13 D2.2 UGA Mm.259799 268706 Slc38a9 Solute carrier family 38, member 9 (Slc38a9), mRNA amino acid transport;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; transport cell;; cell part cell part;; membrane;; membrane part binding ion binding cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 96.9935 144.5449 108.1243 51.5808 39.9752 36.3493 64.3696 85.1343 72.5336 69.5821 68.8314 71.5802 58.8049 65.2224 69.2724 82.9312 66.0086 50.2043 1372136 1447854_s_at 3 chr3:96027511-96027631 3 F2.1 chr3:96025043-96027661 3 F2.1 RSQ Mm.439791 NM_178214 1 1 319190 Hist2h2be histone cluster 2, H2be (Hist2h2be), mRNA. Systemic lupus erythematosus CLASS Human Diseases; Immune Disorders; Systemic lupus erythematosus [PATH:mmu05322] chromosome;; DNA binding;; nucleosome;; nucleosome assembly;; nucleus;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein-DNA complex binding nucleic acid binding;; protein binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process cellular component assembly;; cellular macromolecular complex subunit organization;; DNA packaging;; macromolecular complex subunit organization;; organelle organization 488.3495 439.8517 510.3976 304.9297 195.9326 223.9324 460.0718 426.6379 595.3098 588.8741 443.1086 592.4844 353.4108 473.9206 518.2714 406.1823 309.8164 339.7857 1364989 1447936_at 11 chr11:62416295-62418259 11 B2 chr11:62416391-62418311 11 B2 RSQ Mm.270874 XM_001479267 2 1 69221 2410006H16Rik PREDICTED: RIKEN cDNA 2410006H16 gene (2410006H16Rik), mRNA. 225.4187 218.4590 242.4953 72.6205 100.4224 133.5275 52.5276 65.7689 60.0582 63.9488 63.4042 59.1386 85.4695 96.4450 89.0693 100.9766 88.2610 86.6359 1365169 1452914_at 5 G3 chr5:151394447-151395016 5 G3 UGA Mm.279932 100637 N4bp2l1 NEDD4 binding protein 2-like 1 (N4bp2l1), mRNA 356.7345 239.9891 317.0214 150.2744 107.8943 180.3832 652.1103 681.5341 636.2732 635.2449 676.7630 643.8948 731.9257 645.0667 721.5015 723.7875 648.4410 578.7602 1366616 1454996_at 8 E1 chr8:122085931-122086464 8 E1 UGA Mm.36756 72552 Hsdl1 Hydroxysteroid dehydrogenase like 1, mRNA (cDNA clone MGC:86138 IMAGE:6809862) binding;; catalytic activity;; metabolic process;; oxidoreductase activity binding;; catalytic activity oxidoreductase activity metabolic process 721.6166 918.2972 949.5707 370.9852 326.7594 404.0794 315.8921 329.3473 285.8808 251.4429 312.7301 229.4950 310.0194 253.6708 263.7630 309.2630 335.6291 267.3888 1372382 1455854_a_at 5 F chr5:114389787-114389880 5 F UGA Mm.389682 231637 Ssh1 CDNA clone IMAGE:40094316 Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] actin binding;; cytoplasm;; cytoskeleton;; dephosphorylation;; hydrolase activity;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 151.7871 251.9386 257.8274 82.0624 93.3303 140.5262 35.1530 40.5435 24.9877 40.1090 31.2311 42.1871 23.2979 23.5035 29.3640 29.2664 25.3932 30.1752 1372389 1455980_a_at 10 chr10:88875342-88875663 10 C2 chr10:88871567-88906712 10 C2 RSQ Mm.11982 NM_001033331 3 2 237436 Gas2l3 growth arrest-specific 2 like 3 (Gas2l3), transcript variant 1, mRNA. cell cycle arrest cellular process cell cycle;; cell cycle process 74.9766 142.2192 140.9650 44.2073 46.3918 60.9846 42.5687 45.7383 39.1114 47.6792 47.3664 46.5851 42.8895 44.1741 40.1947 41.5943 47.9810 48.2058 1367278 1456164_at 4 chr4:155578676-155578957 4 E2 chr4:155577202-155580137 4 E2 RSQ XM_001001227 2 1 100382 AW011738 PREDICTED: expressed sequence AW011738 (AW011738), mRNA. 485.8563 414.8404 472.9852 172.8004 216.7630 308.0064 316.2180 355.9822 290.6315 323.9571 333.3767 310.5304 258.0851 276.6605 247.2337 322.2766 264.0408 202.2588 1372409 1456378_s_at 11 D chr11:97950068-97950144 11 D UGA Mm.218350 72194 RP23-309H19.11 Fbxl20 F-box and leucine-rich repeat protein 20, mRNA (cDNA clone IMAGE:3593425) cytoplasm;; modification-dependent protein catabolic process;; protein binding cell;; cell part cell part;; intracellular;; intracellular part binding protein binding cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 75.7605 92.7452 98.8037 30.3938 22.0820 49.4016 16.5392 17.9946 19.9049 17.7508 19.9299 19.0021 17.3954 15.6815 19.2518 19.6695 19.7387 15.3176 1367506 1456574_at 6 chr6:28189936-28190071 6 A3.2 chr6:28189930-28211601 6 A3.2 RSQ Mm.84441 NM_001081678 1 1 627049 Zfp800 zinc finger protein 800 (Zfp800), mRNA. DNA binding;; intracellular;; metal ion binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 291.3386 253.7559 309.2472 112.2117 101.8232 141.9715 128.6437 107.1757 90.8067 117.8486 118.1624 114.0760 108.3965 102.7679 114.5721 102.9618 108.4693 87.2166 1367514 1456607_at 1 chr1:9710724-9711167 1 A2 UGA Mm.440951 Transcribed locus 201.1138 146.0964 184.8560 72.2464 78.6596 67.0847 62.4340 56.9473 48.1517 52.9424 63.9114 52.7915 67.2801 56.1606 67.1780 67.4667 67.7869 69.7585 1367525 1456634_at 2 chr2:156841569-156842128 2 H1 chr2:156836176-156905000 2 H1 RSQ Mm.79466 XM_283804 1 1 320706 RP23-430P1.3 9830001H06Rik PREDICTED: RIKEN cDNA 9830001H06 gene (9830001H06Rik), mRNA. 90.3975 127.3720 141.8262 52.4077 46.2720 74.3320 108.4330 116.3607 117.1563 112.1598 119.4677 105.3199 53.2439 106.8071 70.6173 59.0790 72.4816 73.2292 1368061 1457264_at 15 D2 chr15:66455198-66455539 15 D2 UGA Mm.267473 239510 Phf20l1 PHD finger protein 20-like 1, mRNA (cDNA clone MGC:175576 IMAGE:40130992) metal ion binding;; nucleic acid binding;; zinc ion binding binding ion binding;; nucleic acid binding 82.1429 149.1382 96.6259 44.9973 61.2479 52.6547 53.9160 53.6090 60.2531 45.8330 45.1151 36.8853 31.9616 29.3745 25.0826 25.7561 34.5734 32.4998 1368357 1457583_at 3 chr3:153067498-153067892 3 H3 UGA Mm.451194 Transcribed locus 105.7152 126.9824 125.1352 59.8199 52.5944 64.6538 121.1908 122.8923 115.5732 131.4251 120.6712 115.0318 113.5427 117.8196 117.9005 131.5908 116.0422 113.3965 1368564 1457842_at chr4:34774663-34775048 4 A5 IPA ESTs 196.2668 240.8495 399.4211 85.5770 109.5723 149.9129 29.6111 24.8509 26.9169 29.5854 25.2294 22.3858 26.6862 23.7562 19.7754 25.9283 25.7191 38.2303 1372530 1458297_s_at 1 E4-F chr1:122371291-122390661 1 E2.3 UGA Mm.1856 17167 Marco Macrophage receptor with collagenous structure (Marco), mRNA integral to membrane;; membrane;; receptor activity;; scavenger receptor activity cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity 91.0496 60.4076 35.7186 14.9630 19.4458 13.7459 7.8232 8.1201 11.3287 9.3004 8.6522 7.8349 7.9708 9.4136 9.4300 7.9921 8.0246 7.7543 1372536 1458327_x_at 5 F UG5 Mm.440571 231583 Slc26a1 Solute carrier family 26 (sulfate transporter), member 1, mRNA (cDNA clone MGC:29387 IMAGE:5055098) chloride transmembrane transporter activity;; chloride transport;; integral to membrane;; membrane;; oxalate transmembrane transporter activity;; oxalate transport;; secondary active sulfate transmembrane transporter activity;; sulfate transmembrane transporter activity;; sulfate transport;; transport;; transporter activity cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 268.0939 214.6604 334.1558 104.0652 123.9333 76.6832 100.4513 108.7074 133.5344 121.8510 122.3777 118.2235 101.6485 79.3421 102.2863 97.9616 110.1812 79.6143 1372658 1459860_x_at 3 F1 chr3:83967687-83967725 3 F1 UGA Mm.44876 80890 Trim2 Tripartite motif-containing 2 (Trim2), mRNA cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding