A 1 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen A 2 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen A 3 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen A 4 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen A 5 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen A 6 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen B 7 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen B 8 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen B 9 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen B 10 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen B 11 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen B 12 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen C 13 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen C 14 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen C 15 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen C 16 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen C 17 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen C 18 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Gene Property Filtering 18 arrays and 45101 genes in the input dataset 18 arrays and 45 genes in the output dataset. 45056 genes excluded for Well ID not being in local list 'EG1-test-1-FC'. A A A A A A B B B B B B C C C C C C 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 1059.9895 1371.2126 1191.1804 3052.1127 2355.5366 1996.1509 1837.6283 1895.9957 1996.2630 1950.5557 1853.1011 1882.8204 1774.6864 1697.6241 1816.4391 1771.5154 1662.1674 1514.9834 1327556 1415737_at 19 chr19:17475266-17475800 19 B chr19:17468572-17475825 19 B RSQ Mm.7013 NM_019437 1 1 54391 Rfk riboflavin kinase (Rfk), mRNA. Metabolic pathways CLASS Metabolism; Metabolism of Cofactors and Vitamins; Riboflavin metabolism [PATH:mmu00740];; Riboflavin metabolism ATP binding;; cytoplasm;; kinase activity;; magnesium ion binding;; metal ion binding;; nucleotide binding;; riboflavin biosynthetic process;; riboflavin kinase activity;; transferase activity;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process 871.5681 569.6519 706.1201 1579.0987 2254.3835 1048.7630 33.9803 28.9203 48.1670 30.2012 27.1749 32.8562 25.5623 26.8776 29.4337 26.5491 27.9839 27.0691 1327771 1416025_at 3 41.3 cM chr3:82816782-82818911 3 E3 chr3:82811817-82818971 3 E3 RSQ Mm.16422 NM_133862 1 1 99571 Fgg fibrinogen gamma chain (Fgg), mRNA. Complement and coagulation cascades CLASS Cellular Processes; Immune System; Complement and coagulation cascades [PATH:mmu04610] blood coagulation;; calcium ion binding;; cell cortex;; extracellular region;; fibrinogen complex;; platelet activation;; protein binding, bridging;; protein polymerization;; receptor binding;; signal transduction cell;; cell part;; extracellular region;; extracellular region part;; macromolecular complex cell part;; extracellular region part;; extracellular space;; fibrinogen complex;; intracellular;; intracellular part;; protein complex binding ion binding;; protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; multicellular organismal process;; regulation of biological process;; response to stimulus cell activation;; cell communication;; cellular component assembly;; cellular macromolecular complex subunit organization;; coagulation;; macromolecular complex subunit organization;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; response to external stimulus;; response to stress 979.6495 1075.5182 1140.5109 2999.7756 2512.5590 1973.7362 1230.5251 1280.2783 1465.9252 1408.1519 1280.9575 1419.1541 1418.5039 1443.6126 1541.6647 1409.9153 1377.7522 1325.7000 1327926 1416229_at 19 chr19:17469703-17474242 19 B chr19:17468572-17475825 19 B RSQ Mm.7013 NM_019437 1 1 54391 Rfk riboflavin kinase (Rfk), mRNA. Metabolic pathways CLASS Metabolism; Metabolism of Cofactors and Vitamins; Riboflavin metabolism [PATH:mmu00740];; Riboflavin metabolism ATP binding;; cytoplasm;; kinase activity;; magnesium ion binding;; metal ion binding;; nucleotide binding;; riboflavin biosynthetic process;; riboflavin kinase activity;; transferase activity;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process 1086.4877 1056.3993 1062.5740 2663.5479 2133.3686 1846.2630 1469.5253 1404.2100 1617.0403 1608.4305 1405.6445 1599.8926 1946.0977 1622.6554 1673.0048 1722.1448 1557.8427 1532.3384 1327927 1416230_at 19 chr19:17474367-17474914 19 B chr19:17468572-17475825 19 B RSQ Mm.7013 NM_019437 1 1 54391 Rfk riboflavin kinase (Rfk), mRNA. Metabolic pathways CLASS Metabolism; Metabolism of Cofactors and Vitamins; Riboflavin metabolism [PATH:mmu00740];; Riboflavin metabolism ATP binding;; cytoplasm;; kinase activity;; magnesium ion binding;; metal ion binding;; nucleotide binding;; riboflavin biosynthetic process;; riboflavin kinase activity;; transferase activity;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process 2320.9894 2829.6883 2109.0908 6455.8466 5660.4998 6009.0201 763.2174 756.7914 896.0656 858.0582 729.7227 844.6883 1035.9603 767.4174 946.9220 721.6506 780.2827 571.6425 1328061 1416401_at 2 49.6 cM chr2:93259294-93259810 2 E1 chr2:93259272-93303103 2 E1 RSQ Mm.4261 NM_001136055 2 1 12521 RP23-70K10.2 Cd82 CD82 antigen (Cd82), transcript variant 2, mRNA. p53 signaling pathway CLASS Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 120.5971 155.6736 150.1349 347.2172 257.0916 272.5061 2725.9996 2806.0964 802.0430 734.4321 2673.9977 702.4433 234.9824 228.5365 290.1378 416.5916 379.8765 532.6616 1328194 1416576_at 11 chr11:117827755-117827967 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 17.8044 20.1361 18.3384 49.2846 28.3416 46.7672 248.9299 268.4852 653.5010 643.1115 246.2027 725.4607 255.1171 453.8417 590.9852 134.6512 73.0052 94.5830 1343687 1418507_s_at 10 C2|10 52.0 cM chr10:94874243-94874582 10 C2 UGA Mm.474283 216233 Socs2 Suppressor of cytokine signaling 2 (Socs2), mRNA Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 858.1519 967.6132 975.6519 1989.2497 2014.3242 1854.3332 1268.0774 1314.3871 1554.0479 1543.3245 1246.4468 1547.7413 1201.2075 1116.8961 888.2387 1476.3819 1543.8367 1159.0891 1329833 1418591_at 9 chr9:54562630-54563100 9 A5.3 chr9:54547365-54564119 9 A5.3 RSQ Mm.28437 NM_021422 2 2 58233 Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA. heat shock protein binding;; membrane;; metal ion binding;; protein folding;; unfolded protein binding;; zinc ion binding cell;; cell part cell part;; membrane binding ion binding;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 363.2998 398.6748 439.2471 799.2239 919.1620 1058.8670 592.7230 585.9001 828.5892 798.7462 588.6662 792.4805 600.6055 563.9546 507.3355 773.4742 683.3550 538.9555 1329834 1418592_at 9 chr9:54558361-54562524 9 A5.3 chr9:54547365-54564119 9 A5.3 RSQ Mm.28437 NM_021422 2 2 58233 Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA. heat shock protein binding;; membrane;; metal ion binding;; protein folding;; unfolded protein binding;; zinc ion binding cell;; cell part cell part;; membrane binding ion binding;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1039.0083 767.2390 570.4251 1238.0962 2215.4173 1460.8151 37.1475 34.5517 40.1225 42.1413 38.1795 42.1493 33.1825 49.1826 37.5186 25.6519 41.2480 35.0651 1331607 1421009_at 12 chr12:27129411-27129968 12 A2 chr12:27127607-27141317 12 A2 RSQ Mm.24045 NM_021384 1 1 58185 Rsad2 radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA. catalytic activity;; defense response to virus;; endoplasmic reticulum;; iron ion binding;; iron-sulfur cluster binding;; membrane;; metal ion binding;; response to virus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; catalytic activity ion binding;; metal cluster binding immune system process;; multi-organism process;; response to stimulus immune effector process;; immune response;; response to biotic stimulus;; response to other organism;; response to stress 36.8179 32.6977 47.5826 137.0905 121.0724 106.5132 195.1879 183.1424 842.1944 887.5067 193.3896 963.3258 1420.4606 1362.1924 1505.7619 301.7720 176.5317 187.4154 1344534 1422103_a_at 11 60.5 cM chr11:100642207-100642625 11 D chr11:100642044-100711899 11 D RSQ Mm.34064 NM_001113563 2 1 20851 RP23-279L23.3 Stat5b signal transducer and activator of transcription 5B (Stat5b), mRNA. Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] Human Diseases; Cancers; Pathways in cancer [PA;; Chemokine signaling pathway;; Chronic myeloid leukemia;; ErbB signaling pathway;; Jak-STAT signaling pathway;; Pathways in cancer calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; development of secondary female sexual characteristics;; development of secondary male sexual characteristics;; development of secondary male sexual characteristics;; DNA binding;; female pregnancy;; female pregnancy;; JAK-STAT cascade;; lactation;; lipid storage;; luteinization;; natural killer cell differentiation;; negative regulation of apoptosis;; negative regulation of erythrocyte differentiation;; nucleus;; Peyer's patch development;; positive regulation of activated T cell proliferation;; positive regulation of activated T cell proliferation;; positive regulation of B cell differentiation;; positive regulation of cell proliferation;; positive regulation of gamma-delta T cell differentiation;; positive regulation of inflammatory response;; positive regulation of interleukin-2 biosynthetic process;; positive regulation of lymphocyte differentiation;; positive regulation of mitotic cell cycle;; positive regulation of multicellular organism growth;; positive regulation of multicellular organism growth;; positive regulation of natural killer cell differentiation;; positive regulation of natural killer cell mediated cytotoxicity;; positive regulation of natural killer cell proliferation;; positive regulation of survival gene product expression;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; progesterone metabolic process;; protein binding;; regulation of cell adhesion;; regulation of epithelial cell differentiation;; regulation of steroid metabolic process;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; response to interleukin-15;; response to interleukin-2;; response to interleukin-4;; sex differentiation;; signal transducer activity;; signal transduction;; T cell differentiation in the thymus;; T cell homeostasis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription factor activity biological adhesion;; biological regulation;; cell killing;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus;; rhythmic process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell activation;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; female pregnancy;; hormone metabolic process;; immune effector process;; immune response;; immune system development;; leukocyte activation;; leukocyte homeostasis;; leukocyte mediated cytotoxicity;; macromolecule localization;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of growth;; positive regulation of immune system process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of homeostatic process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; response to chemical stimulus;; response to external stimulus;; response to stress 139.7737 121.2675 149.3812 632.3417 548.6958 716.4694 144.2691 152.8193 146.0964 134.5965 151.2223 139.6568 156.2494 147.0852 135.8287 143.9437 141.7213 146.4853 1332863 1422740_at 17 chr17:43222467-43225181 17 B3 chr17:43153503-43226137 17 B3 RSQ Mm.200792 NM_178589 1 1 94185 Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA. Cytokine-cytokine receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] apoptosis;; axon;; integral to membrane;; membrane;; neuron apoptosis;; protein binding;; receptor activity;; signal transduction cell;; cell part cell part;; cell projection;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; death;; regulation of biological process cell communication;; cell death;; regulation of biological process;; regulation of cellular process 379.3461 486.8553 432.0405 1122.0693 1329.1915 1092.1397 2598.5330 2717.8427 2871.6525 3001.6628 2736.9420 2944.8962 2797.5716 2932.8484 2751.6060 2768.6823 2894.5080 2155.8864 1333195 1423166_at 5 2.0 cM chr5:17288429-17288766 5 A3 chr5:17287507-17355610 5 A3 RSQ NM_001159556 5 1 12491 Cd36 CD36 antigen (Cd36), transcript variant 5, mRNA. TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Adipocytokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] Cellular Processes; Immune System; Hem;; ECM-receptor interaction;; Hematopoietic cell lineage;; PPAR signaling pathway apoptotic cell clearance;; cell adhesion;; cholesterol transport;; high-density lipoprotein binding;; integral to membrane;; membrane;; protein binding;; receptor activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological adhesion;; cellular component organization;; cellular process;; establishment of localization;; localization cell adhesion;; establishment of localization;; membrane organization;; transport;; vesicle-mediated transport 494.4093 474.9598 614.5408 1407.8149 1181.4982 2400.8203 2294.9077 2190.1389 2245.2478 2252.6339 2259.5349 2327.4852 925.7221 950.2809 1215.3054 649.2134 764.0944 680.9244 1345554 1425837_a_at 3 chr3:51055003-51055460 3 C chr3:51028368-51055576 3 C RSQ Mm.86541 NM_009834 2 2 12457 Ccrn4l CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA. Selective expression of chemokine receptors during T-cell polarization rhythmic process rhythmic process 660.1404 312.4127 342.2615 1290.7054 1273.4570 1544.4929 349.1785 330.2075 279.4258 299.0790 302.5891 278.3966 390.0216 344.1610 418.7813 384.1602 448.3342 308.2104 1345980 1426956_a_at 2 chr2:121024019-121024141 2 E5 chr2:121022452-121097122 2 E5 RSQ Mm.215389 NM_013735 1 1 27223 RP23-437L13.2 Trp53bp1 transformation related protein 53 binding protein 1 (Trp53bp1), mRNA. cellular response to DNA damage stimulus;; damaged DNA binding;; DNA binding;; DNA repair;; intracellular;; kinetochore;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; replication fork;; response to DNA damage stimulus;; telomeric DNA binding;; transcription;; transcription factor binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to stress 761.2545 526.6445 620.9314 1187.7547 1416.2861 1356.2756 226.0353 267.9336 233.2908 267.1519 256.1629 274.4983 317.3030 284.0210 316.9650 336.3186 360.8279 299.9436 1335793 1426957_at 2 chr2:121024130-121025404 2 E5 chr2:121022452-121097122 2 E5 RSQ Mm.215389 NM_013735 1 1 27223 RP23-437L13.2 Trp53bp1 transformation related protein 53 binding protein 1 (Trp53bp1), mRNA. cellular response to DNA damage stimulus;; damaged DNA binding;; DNA binding;; DNA repair;; intracellular;; kinetochore;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; replication fork;; response to DNA damage stimulus;; telomeric DNA binding;; transcription;; transcription factor binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex binding nucleic acid binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to stress 2469.0588 1833.6796 2089.5172 5094.7275 4581.5947 5555.6635 758.9211 784.7345 1125.1624 1045.3071 789.7075 1049.0672 1682.9176 1113.2225 1816.3872 845.2527 743.7337 594.4004 1346063 1427364_a_at 12 6.0 cM chr12:17551678-17558308 12 A1.1 RSQ Mm.34102 NM_013614 1 1 18263 Odc1 ornithine decarboxylase, structural 1 (Odc1), mRNA. Arginine and proline metabolism;; Glutathione metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism [PATH:mmu00480] carboxy-lyase activity;; catalytic activity;; cytosol;; kidney development;; lyase activity;; ornithine decarboxylase activity;; polyamine biosynthetic process;; positive regulation of cell proliferation cell;; cell part cell part;; intracellular;; intracellular part catalytic activity lyase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell proliferation;; cellular metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 476.5445 563.7644 552.1969 1272.9513 1238.3512 1286.3662 963.2323 969.2812 928.1614 957.3741 961.9317 944.2608 931.6113 854.3488 702.5691 783.7269 1259.9573 790.9457 1337468 1434196_at 9 chr9:54563523-54564050 9 A5.3 chr9:54547365-54564119 9 A5.3 RSQ Mm.28437 NM_021422 2 2 58233 Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA. heat shock protein binding;; membrane;; metal ion binding;; protein folding;; unfolded protein binding;; zinc ion binding cell;; cell part cell part;; membrane binding ion binding;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 3553.7718 2629.5130 2549.8264 4510.3187 7803.5445 5477.1646 146.8028 150.9946 160.9076 156.5707 156.2630 171.6313 136.9372 169.0003 154.3591 129.0903 137.9691 168.8063 1337925 1436058_at 12 chr12:27127660-27128137 12 A2 chr12:27127607-27141317 12 A2 RSQ Mm.24045 NM_021384 1 1 58185 Rsad2 radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA. catalytic activity;; defense response to virus;; endoplasmic reticulum;; iron ion binding;; iron-sulfur cluster binding;; membrane;; metal ion binding;; response to virus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; catalytic activity ion binding;; metal cluster binding immune system process;; multi-organism process;; response to stimulus immune effector process;; immune response;; response to biotic stimulus;; response to other organism;; response to stress 20.0007 26.3365 18.2852 42.1835 43.2541 67.4528 43.2910 37.6371 38.3638 38.0619 26.8502 38.2797 36.4858 37.3724 43.8882 35.4514 36.1328 38.5886 1339609 1449248_at 16 16.0 cM chr16:20703385-20703716 16 B1 chr16:20703038-20716709 16 B1 RSQ Mm.177761 NM_009900 1 1 12724 RP23-101H1.9 Clcn2 chloride channel 2 (Clcn2), mRNA. cell differentiation involved in salivary gland development;; chloride channel activity;; chloride channel complex;; chloride ion binding;; chloride transport;; integral to membrane;; ion channel activity;; ion transport;; membrane;; transport;; voltage-gated chloride channel activity;; voltage-gated ion channel activity cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; developmental process;; establishment of localization;; localization;; multicellular organismal process anatomical structure development;; cellular developmental process;; establishment of localization;; multicellular organismal development;; transport 13.8932 16.3582 22.5512 59.7969 39.8737 43.7828 25.8331 31.5116 82.9659 78.6861 31.5116 72.4687 166.3186 137.2517 149.8765 74.5429 65.4503 55.7989 1348627 1450259_a_at 11 60.5 cM chr11:100742343-100745240 11 D chr11:100720716-100746483 11 D RSQ Mm.277403 NM_011488 1 1 20850 RP23-279L23.4 Stat5a signal transducer and activator of transcription 5A (Stat5a), mRNA. EPO Signaling Pathway;; Growth Hormone Signaling Pathway;; IL 2 signaling pathway;; IL 3 signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; IL22 Soluble Receptor Signaling Pathway;; Inhibition of Cellular Proliferation by Gleevec;; TPO Signaling Pathway Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Hu;; Chronic myeloid leukemia;; ErbB signaling pathway;; Jak-STAT signaling pathway;; Pathways in cancer calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; development of secondary female sexual characteristics;; development of secondary male sexual characteristics;; development of secondary male sexual characteristics;; DNA binding;; epithelial cell differentiation involved in prostate gland development;; female pregnancy;; JAK-STAT cascade;; lactation;; lipid storage;; luteinization;; mammary gland development;; natural killer cell differentiation;; negative regulation of apoptosis;; negative regulation of erythrocyte differentiation;; negative regulation of mast cell apoptosis;; nucleus;; peptidyl-tyrosine phosphorylation;; Peyer's patch development;; positive regulation of activated T cell proliferation;; positive regulation of activated T cell proliferation;; positive regulation of B cell differentiation;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; positive regulation of gamma-delta T cell differentiation;; positive regulation of inflammatory response;; positive regulation of interleukin-2 biosynthetic process;; positive regulation of lymphocyte differentiation;; positive regulation of mast cell differentiation;; positive regulation of mast cell proliferation;; positive regulation of mitotic cell cycle;; positive regulation of multicellular organism growth;; positive regulation of natural killer cell differentiation;; positive regulation of natural killer cell mediated cytotoxicity;; positive regulation of survival gene product expression;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; prostate gland epithelium morphogenesis;; protein binding;; regulation of cell adhesion;; regulation of epithelial cell differentiation;; regulation of steroid metabolic process;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; response to peptide hormone stimulus;; signal transducer activity;; signal transduction;; T cell differentiation in the thymus;; T cell homeostasis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription factor activity biological adhesion;; biological regulation;; cell killing;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus;; rhythmic process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell activation;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; female pregnancy;; immune effector process;; immune response;; immune system development;; leukocyte activation;; leukocyte homeostasis;; leukocyte mediated cytotoxicity;; macromolecule localization;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of growth;; positive regulation of immune system process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of homeostatic process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; response to chemical stimulus;; response to endogenous stimulus;; response to external stimulus;; response to stress 179.6531 198.5344 286.7091 1253.8892 1061.2710 1633.7834 492.3222 504.6833 371.3014 367.2456 478.7033 340.8597 429.6674 400.3462 401.6732 413.0708 418.2630 443.7768 1348752 1450731_s_at 17 chr17:43225493-43225794 17 B3 chr17:43153503-43226137 17 B3 RSQ Mm.200792 NM_178589 1 1 94185 Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA. Cytokine-cytokine receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] apoptosis;; axon;; integral to membrane;; membrane;; neuron apoptosis;; protein binding;; receptor activity;; signal transduction cell;; cell part cell part;; cell projection;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; death;; regulation of biological process cell communication;; cell death;; regulation of biological process;; regulation of cellular process 298.6091 398.8186 303.4571 1145.3741 1232.3186 1129.7630 2265.7785 2273.0619 2371.8988 2494.6733 2258.6341 2527.1640 2834.5730 2808.1519 2490.0488 2442.8572 2718.3968 2139.7849 1348794 1450883_a_at 5 2.0 cM chr5:17289115-17294119 5 A3 chr5:17287507-17355610 5 A3 RSQ NM_001159556 5 1 12491 Cd36 CD36 antigen (Cd36), transcript variant 5, mRNA. TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Adipocytokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] Cellular Processes; Immune System; Hem;; ECM-receptor interaction;; Hematopoietic cell lineage;; PPAR signaling pathway apoptotic cell clearance;; cell adhesion;; cholesterol transport;; high-density lipoprotein binding;; integral to membrane;; membrane;; protein binding;; receptor activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological adhesion;; cellular component organization;; cellular process;; establishment of localization;; localization cell adhesion;; establishment of localization;; membrane organization;; transport;; vesicle-mediated transport 39.1388 57.1148 39.5975 98.7144 123.9789 107.2559 1180.6251 1183.6537 1307.1572 1187.2650 1112.6408 1241.4490 1054.0154 1123.1509 903.8691 846.4051 917.9559 816.8495 1340774 1450884_at 5 A3|5 2.0 cM chr5:17287591-17288079 5 A3 UGA Mm.18628 12491 Cd36 CD36 antigen, mRNA (cDNA clone MGC:6068 IMAGE:3481681) TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Adipocytokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; ECM-receptor interaction [PATH:mmu04512] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] Cellular Processes; Immune System; Hem;; ECM-receptor interaction;; Hematopoietic cell lineage;; PPAR signaling pathway apoptotic cell clearance;; cell adhesion;; cholesterol transport;; high-density lipoprotein binding;; integral to membrane;; membrane;; protein binding;; receptor activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological adhesion;; cellular component organization;; cellular process;; establishment of localization;; localization cell adhesion;; establishment of localization;; membrane organization;; transport;; vesicle-mediated transport 372.3557 273.5287 311.6344 899.6148 576.9081 604.2813 791.0511 790.5906 872.6233 828.0332 792.6262 849.7496 810.4266 860.4396 749.3127 988.4214 883.3737 776.9676 1340886 1451019_at colocalizes with Chk and Klc2 chr19:4859625-4860590 19 A chr19:4855128-4860912 19 A RSQ Mm.29561 NM_019861 1 1 56464 Ctsf cathepsin F (Ctsf), mRNA. Lysosome CLASS Cellular Processes; Transport and Catabolism; Lysosome [PATH:mmu04142] cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; hydrolase activity;; lysosome;; peptidase activity;; proteolysis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 95.7515 85.3192 55.7506 190.5392 185.6277 150.1912 1003.3660 961.7216 1082.0582 1040.4849 1025.1026 971.1339 1190.5078 1043.6210 1212.0408 1377.5632 1334.8007 1137.2823 1348960 1451501_a_at 15 4.6 cM chr15:3278002-3290994 15 A1 chr15:3277524-3421487 15 A1 RSQ Mm.3986 NM_001048147 3 1 14600 Ghr growth hormone receptor (Ghr), transcript variant 3, mRNA. AKT Signaling Pathway;; Growth Hormone Signaling Pathway;; Regulation of eIF4e and p70 S6 Kinase;; The IGF-1 Receptor and Longevity;; Trefoil Factors Initiate Mucosal Healing Cytokine-cytokine receptor interaction;; Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytok;; Neuroactive ligand-receptor interaction 2-oxoglutarate metabolic process;; allantoin metabolic process;; citrate metabolic process;; creatine metabolic process;; creatinine metabolic process;; cytokine receptor activity;; endocytosis;; extracellular region;; extrinsic to membrane;; fatty acid metabolic process;; growth hormone receptor activity;; growth hormone receptor signaling pathway;; integral to membrane;; isoleucine metabolic process;; membrane;; nucleus;; oxaloacetate metabolic process;; peptide hormone binding;; plasma membrane;; positive regulation of peptidyl-tyrosine phosphorylation;; protein binding;; receptor activity;; regulation of multicellular organism growth;; succinate metabolic process;; taurine metabolic process;; valine metabolic process cell;; cell part;; extracellular region;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; molecular transducer activity hormone binding;; peptide binding;; protein binding;; signal transducer activity biological regulation;; cellular component organization;; cellular process;; establishment of localization;; growth;; localization;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell communication;; cellular metabolic process;; cellular response to stimulus;; establishment of localization;; macromolecule metabolic process;; membrane organization;; multicellular organism growth;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to endogenous stimulus;; transport;; vesicle-mediated transport 295.6559 361.7630 288.2847 722.2630 653.6039 750.5664 111.0391 109.8522 108.7760 80.7681 99.5872 88.3598 88.3286 107.6774 92.1693 129.9869 97.1084 111.0691 1342264 1454656_at 14 D1|14 30.5 cM chr14:61382914-61383362 14 D1 UGA Mm.149776 219140 Spata13 Spermatogenesis associated 13, mRNA (cDNA clone MGC:170080 IMAGE:8861475) guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; regulation of Rho protein signal transduction;; Rho guanyl-nucleotide exchange factor activity cell;; cell part cell part;; intracellular enzyme regulator activity nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 22.6423 20.6528 36.1766 242.2528 152.9323 183.5801 3532.9631 3291.2873 758.4727 901.1034 3378.5646 879.0435 175.8772 212.4538 268.9634 380.5947 288.2147 403.0422 1349775 1455899_x_at 11 chr11:117827463-117827587 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 48.9595 27.6735 54.1104 297.7746 226.1876 240.6310 2547.2819 2516.3176 501.8186 599.3431 2565.6128 644.3749 154.3001 149.3006 177.7507 288.0805 200.8621 249.8199 1349871 1456212_x_at 11 E2 chr11:117827490-117827770 11 E2 IPA Mm.3468 Socs3 Suppressor of cytokine signaling 3 (Socs3), mRNA 31.5752 23.9949 15.8491 46.1837 67.4658 61.2917 169.0087 194.0938 141.4947 189.2132 210.5635 173.7236 132.9334 208.9297 240.2643 251.3593 182.5427 79.3205 1350770 1428909_at 11 UGA Mm.291551 Transcribed locus 75.2787 66.1066 116.8282 323.1233 265.0227 195.4139 190.9974 193.6008 112.2185 124.8387 179.4459 132.5410 143.2000 94.8071 181.1619 259.3591 202.8283 114.4744 1350962 1429184_at 7 RSQ Mm.458429 NM_001039160 4 2 74558 Gvin1 GTPase, very large interferon inducible 1 (Gvin1), transcript variant B, mRNA. cytoplasm;; GTP binding;; nucleotide binding;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleotide binding 36.5212 36.3106 30.2337 125.5968 120.8749 148.6645 21.0987 27.0838 24.2846 22.3089 19.9506 21.3659 22.5312 22.1812 18.2362 24.0501 16.4808 18.2531 1352813 1431742_at 16 chr16:93344031-93344552 16 C4 UGA Mm.458688 Transcribed locus 28.3046 24.6838 31.4849 68.7762 52.9439 51.6702 30.0462 28.0024 23.6206 24.8092 26.9214 26.3588 21.3713 33.9265 36.4868 23.2157 21.5238 23.2433 1353617 1432885_at chr3:10221048-10221580 3 A1 IPA 4632432E15Rik RIKEN cDNA 4632432E15 gene 91.6713 76.3957 68.4044 165.3991 164.6009 165.3143 35.9519 34.3864 27.6077 36.5995 36.6864 40.5569 39.0559 32.0998 32.3968 27.7166 38.1670 37.5245 1354336 1433870_at 11 chr11:96796382-96796776 11 D chr11:96790637-96796962 11 D RSQ Mm.342551 NM_146026 1 1 217138 RP23-353J21.10 Atad4 ATPase family, AAA domain containing 4 (Atad4), mRNA. 56.7200 47.7733 49.6660 130.7534 86.4200 117.1841 3024.5179 3064.9019 2926.5427 2833.6896 3053.8947 2886.1453 3077.3845 2649.4466 2940.1852 2696.1797 2956.0764 2761.1862 1354873 1434909_at 4 11.4 cM chr4:33108577-33109064 4 A5 chr4:33069972-33109155 4 A5 RSQ Mm.300814 NM_027491 1 1 52187 RP23-360H6.3 Rragd Ras-related GTP binding D (Rragd), mRNA. cytoplasm;; GTP binding;; nucleotide binding;; nucleus;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleotide binding;; protein binding 13.9641 17.0712 14.9679 47.5794 36.5826 49.9831 18.1659 16.1062 18.0413 18.3883 17.0495 14.5679 19.0553 18.3178 18.4741 20.3049 17.5379 20.2349 1354916 1434990_at 11 C chr11:87040513-87040913 11 C UG5 Mm.341988 320472 RP23-209O5.1 Ppm1e Protein phosphatase 1E (PP2C domain containing), mRNA (cDNA clone MGC:170530 IMAGE:8861925) catalytic activity;; cytoplasm;; hydrolase activity;; magnesium ion binding;; manganese ion binding;; metal ion binding;; nucleus;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein serine/threonine phosphatase activity;; protein serine/threonine phosphatase complex cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex;; protein serine/threonine phosphatase complex binding;; catalytic activity hydrolase activity;; ion binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 93.0904 66.2764 81.5427 285.4860 215.7075 267.1162 282.0064 286.3120 306.6487 324.4460 289.8785 280.9539 601.0149 553.5963 453.5485 590.3444 562.3186 446.3992 1355327 1435657_at 12 chr12:92871911-92872037 12 D3 chr12:92871448-93024876 12 D3 RSQ Mm.23125 NM_175367 1 1 108800 Ston2 stonin 2 (Ston2), mRNA. clathrin adaptor complex;; cytoplasm;; endocytosis;; intracellular protein transport;; membrane;; protein binding;; regulation of endocytosis;; vesicle-mediated transport cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; membrane part;; protein complex binding protein binding biological regulation;; cellular component organization;; cellular process;; establishment of localization;; localization;; regulation of biological process cellular localization;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; membrane organization;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of localization;; transport;; vesicle-mediated transport 123.8638 114.2557 101.2511 280.9402 198.3253 231.0111 78.2396 78.4138 87.4889 83.0110 89.4352 93.0758 83.3886 79.5346 88.7867 77.5333 76.9779 74.8556 1356168 1437087_at 5 chr5:105918653-105918989 5 E5 UGA Mm.439781 Transcribed locus 187.3526 208.9603 140.4213 411.2675 411.1863 418.8038 97.7408 93.8545 91.0838 79.2993 93.5580 94.4446 90.5016 92.7842 87.2703 96.6170 83.7337 87.9772 1356572 1437865_at 14 30.5 cM chr14:61381518-61381899 14 D1 chr14:61253565-61383393 14 D1 RSQ NM_001033272 1 1 219140 Spata13 spermatogenesis associated 13 (Spata13), mRNA. guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; regulation of Rho protein signal transduction;; Rho guanyl-nucleotide exchange factor activity cell;; cell part cell part;; intracellular enzyme regulator activity nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 9.9121 9.9725 12.1653 143.1459 227.7468 233.6210 9.4201 9.6246 9.9331 9.9334 10.1337 9.4649 9.9078 9.8482 9.6523 9.5480 9.6981 8.8654 1371585 1440927_x_at 15 E1 chr15:77464408-77464880 15 E1 UG5 Mm.17957 328563 Apol11b Apolipoprotein L 11b (Apol11b), mRNA 605.6519 591.2656 418.8741 1201.7630 1053.0408 1090.3186 60.0933 54.9991 97.6009 73.3677 65.5116 71.7715 64.8402 74.6924 66.4189 66.4316 56.9612 64.2739 1361995 1444566_at 7 E3|7 50.0 cM chr7:107653850-107654181 7 E3 UGA Mm.171378 22228 Ucp2 Uncoupling protein 2 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:13955 IMAGE:4205625) binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrial transport;; mitochondrion;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; transport 80.4260 92.2921 71.1147 193.4357 179.4297 228.2041 40.6039 37.3218 37.7426 41.8892 38.7378 40.4878 51.0242 44.0883 44.0227 42.1911 43.0752 57.7051 1364787 1447485_at 13 C1 chr13:76194476-76194749 13 C1 UGA Mm.167172 238725 Gpr150 G protein-coupled receptor 150, mRNA (cDNA clone MGC:148214 IMAGE:40107174) G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; plasma membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 139.7764 163.7443 107.8449 330.3191 287.7759 477.1664 67.6061 59.3490 59.8689 53.4224 59.1540 53.0310 54.8123 58.2967 51.9127 66.1232 61.7586 41.0333 1366993 1455604_at 1 30.8 cM chr1:64777313-64777707 1 C2 chr1:64777131-64784324 1 C2 RSQ Mm.150813 NM_001042659 2 1 14367 Fzd5 frizzled homolog 5 (Drosophila) (Fzd5), transcript variant 2, mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Endocrine System; Melanogenesis [PATH:mmu04916] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210] Human Diseases; Cancers; Basal cell carcinom;; Colorectal cancer;; Melanogenesis;; Pathways in cancer;; Wnt signaling pathway angiogenesis;; cell differentiation;; cell maturation;; cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; Golgi apparatus;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; plasma membrane;; protein binding;; receptor activity;; signal transducer activity;; signal transduction;; transmembrane receptor activity;; Wnt receptor signaling pathway cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; molecular transducer activity protein binding;; signal transducer activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cellular developmental process;; developmental maturation;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 199.8901 170.4654 181.4637 482.2465 326.8741 409.1942 381.4622 379.3611 434.9307 461.4152 376.8089 405.3658 285.6279 534.8928 481.0047 419.9378 371.6794 322.8209 1367299 1456204_at 14 chr14:31941822-31941933 14 B UG5 Mm.379116 Transcribed locus, strongly similar to NP_001118239.1 hypothetical protein LOC440957 [Homo sapiens] 11.0851 11.0851 13.1410 242.0964 279.7075 375.0408 12.0698 10.5350 11.2894 10.6782 11.7976 10.1105 9.9204 12.6395 10.9931 11.1843 10.3570 11.5033 1368099 1457307_at 15 E1 chr15:77464408-77464698 15 E1 UG5 Mm.17957 328563 Apol11b Apolipoprotein L 11b (Apol11b), mRNA