A 1 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen A 2 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen A 3 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen B 4 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen B 5 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen B 6 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen The input data set contained 45101 genes The filtered output data set contains 168 genes 37427 gene rows removed by Include where A-B T-test p-value (two tailed) <= 0.05 7506 gene rows removed by Include where A-B Mean Difference >= 1 A A A B B B 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen A-B p-Value A-B Mean Difference A Mean B Mean Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 1523.0491 1576.7918 1560.4356 397.0232 395.9849 384.8493 7.1266235e-08 1.98424 10.60109 8.61684 1327679 1415899_at 8 C2-D1|8 38.6 cM chr8:87500883-87501393 8 C3 UGA Mm.1167 16477 Junb Jun-B oncogene, mRNA (cDNA clone MGC:6021 IMAGE:3592704) GATA3 participate in activating the Th2 cytokine genes expression cellular process;; decidualization;; DNA binding;; embryonic process involved in female pregnancy;; in utero embryonic development;; labyrinthine layer blood vessel development;; nucleus;; positive regulation of cell differentiation;; protein dimerization activity;; regulation of cell cycle;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; trophectodermal cell differentiation;; trophectodermal cell differentiation;; vasculogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multi-organism process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; embryonic development;; female pregnancy;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; reproductive process in a multicellular organism 503.5929 520.5099 516.2546 168.7229 188.3543 190.8918 0.00078692239 1.49314 9.00394 7.51081 1343221 1416065_a_at 8 chr8:11611620-11611723 8 A1.1 chr8:11611582-11635689 8 A1.1 RSQ Mm.12459 NM_133971 1 1 102334 Ankrd10 ankyrin repeat domain 10 (Ankrd10), mRNA. 6338.8642 6196.7090 6267.6941 1505.3542 1551.8456 1443.0410 6.3364316e-05 2.06349 12.61367 10.55018 1327943 1416250_at 1 71.0 cM chr1:135973961-135975525 1 E4 chr1:135971441-135975732 1 E4 RSQ Mm.392646 NM_007570 1 1 12227 Btg2 B-cell translocation gene 2, anti-proliferative (Btg2), mRNA. BTG family proteins and cell cycle regulation anterior/posterior pattern formation;; negative regulation of apoptosis;; neuron differentiation;; protein amino acid methylation;; protein binding;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; transcription binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to stress 1763.3867 1666.5310 1757.0016 414.8919 423.1519 399.0408 5.8611467e-07 2.06788 10.75522 8.68734 1327963 1416273_at 12 56.0 cM chr12:112692639-112692973 12 F1 chr12:112683139-112693229 12 F1 RSQ Mm.255332 NM_009396 1 1 21928 Tnfaip2 tumor necrosis factor, alpha-induced protein 2 (Tnfaip2), mRNA. angiogenesis;; cell differentiation;; multicellular organismal development anatomical structure formation;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cellular developmental process;; multicellular organismal development 273.2035 303.9363 290.5736 66.7361 63.3636 59.8105 4.3076371e-06 2.19197 8.17474 5.98277 1327998 1416318_at 13 12.0 cM chr13:32934621-32937204 13 A3.2 chr13:32933960-32943054 13 A3.2 RSQ Mm.20144 NM_025429 1 1 66222 RP23-427P14.4 Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a (Serpinb1a), mRNA. cytoplasm;; endopeptidase inhibitor activity;; regulation of protein catabolic process;; serine-type endopeptidase inhibitor activity cell;; cell part cell part;; intracellular;; intracellular part enzyme regulator activity enzyme inhibitor activity biological regulation;; metabolic process;; regulation of biological process catabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of metabolic process 963.3854 916.9217 957.6589 428.5296 402.8232 406.8741 6.9500502e-06 1.19677 9.88533 8.68856 1328081 1416431_at 18 chr18:67561958-67562376 18 E1 chr18:67550384-67562403 18 E1 RSQ Mm.181860 NM_026473 1 1 67951 Tubb6 tubulin, beta 6 (Tubb6), mRNA. Gap junction CLASS Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] GTP binding;; GTPase activity;; microtubule;; microtubule-based movement;; microtubule-based process;; nucleotide binding;; protein complex;; protein polymerization;; structural molecule activity cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding;; catalytic activity;; structural molecule activity hydrolase activity;; nucleotide binding anatomical structure formation;; cellular component biogenesis;; cellular component organization;; cellular process cellular component assembly;; cellular macromolecular complex subunit organization;; macromolecular complex subunit organization;; microtubule-based process;; protein complex biogenesis 2725.9996 2806.0964 2673.9977 802.0430 734.4321 702.4433 0.0002535509 1.87581 11.41723 9.54142 1328194 1416576_at 11 chr11:117827755-117827967 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 5921.1519 5934.3151 5847.0438 2053.7697 1977.9902 1964.7678 3.6811952e-05 1.56200 12.52667 10.96467 1328407 1416840_at X chrX:10296247-10296743 X A1.1 chrX:10294619-10296823 X A1.1 RSQ Mm.29429 NM_026524 1 1 68041 RP23-130J1.1 Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) (Mid1ip1), mRNA. cytoplasm;; microtubule;; microtubule cytoskeleton;; negative regulation of microtubule depolymerization;; nucleus;; protein binding;; protein C-terminus binding cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process cellular component disassembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; microtubule-based process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process 4687.2495 4806.2947 4760.1034 509.0127 460.1191 462.8921 0.0001049456 3.31669 12.21400 8.89732 1328588 1417065_at 18 16.0 cM chr18:35024067-35024594 18 B1 chr18:35020860-35024610 18 B1 RSQ Mm.181959 NM_007913 1 1 13653 Egr1 early growth response 1 (Egr1), mRNA. Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway Prion diseases CLASS Human Diseases; Neurodegenerative Diseases; Prion diseases [PATH:mmu05020] DNA binding;; intracellular;; metal ion binding;; negative regulation of transcription from RNA polymerase II promoter;; nucleic acid binding;; nucleus;; nucleus;; regulation of transcription, DNA-dependent;; response to protein stimulus;; T cell differentiation;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cellular developmental process;; cellular metabolic process;; immune system development;; leukocyte activation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus 1169.8554 1150.9218 1121.9598 388.9852 386.9813 424.5408 0.00016458935 1.52101 10.16416 8.64315 1328869 1417406_at 7 chr7:28274785-28275298 7 A3 chr7:28271971-28275333 7 A3 RSQ Mm.153684 NM_018820 1 1 55942 Sertad1 SERTA domain containing 1 (Sertad1), mRNA. cytoplasm;; negative regulation of cell growth;; nucleus;; positive regulation of transcription;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription activator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription activator activity biological regulation;; cellular process;; growth;; metabolic process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cell growth;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process 5984.1681 6025.9914 6056.2174 1095.3497 1299.2783 1321.6060 0.0013833269 2.28646 12.55604 10.26958 1343546 1417714_x_at 11 16.0 cM RSQ Mm.196110 NM_008218 2 2 15122 Hba-a1 hemoglobin alpha, adult chain 1 (Hba-a1), mRNA. erythrocyte development;; heme binding;; hemoglobin complex;; in utero embryonic development;; iron ion binding;; metal ion binding;; oxygen binding;; oxygen transport;; oxygen transporter activity;; transport cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; transporter activity ion binding;; oxygen binding;; substrate-specific transporter activity;; tetrapyrrole binding biological regulation;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; multicellular organismal process anatomical structure development;; cellular developmental process;; embryonic development;; establishment of localization;; immune system development;; multicellular organismal development;; regulation of biological quality;; transport 532.5718 537.7103 538.7268 236.1525 238.7075 257.7410 0.0010377129 1.13616 9.06698 7.93082 1329123 1417719_at 8 31.0 cM chr8:59961527-59964341 8 B2 chr8:59961521-59966654 8 B2 RSQ Mm.118 NM_021788 1 1 60406 Sap30 sin3 associated polypeptide (Sap30), mRNA. negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; Sin3 complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding protein binding biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 527.4612 515.7743 537.3162 190.0769 172.2705 189.3413 0.00025213365 1.51978 9.04105 7.52127 1329183 1417793_at 11 chr11:58035687-58036058 11 B1.3 chr11:58028478-58036285 11 B1.3 RSQ Mm.458517 NM_019440 1 1 54396 RP24-499A8.1 Irgm2 immunity-related GTPase family M member 2 (Irgm2), mRNA. GTPase activity catalytic activity hydrolase activity 865.7190 894.0942 1034.7201 151.2267 124.5341 160.9145 8.4432687e-05 2.68198 9.85902 7.17704 1329299 1417930_at 10 70.0 cM chr10:127098035-127098540 10 D3 chr10:127097973-127103759 10 D3 RSQ Mm.336898 NM_001122895 2 1 17937 Nab2 Ngfi-A binding protein 2 (Nab2), transcript variant 2, mRNA. endochondral ossification;; myelination;; negative regulation of transcription;; nucleus;; regulation of epidermis development;; regulation of transcription;; regulation of transcription, DNA-dependent;; Schwann cell differentiation;; transcription;; transcription regulator activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle transcription regulator activity transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; ensheathment of neurons;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; ossification;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; system process 1616.0867 1573.0423 1580.4144 400.5288 415.3885 399.0308 6.6030931e-07 1.97309 10.63457 8.66148 1329642 1418349_at 18 15.0 cM chr18:36664709-36665151 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 4203.5671 4298.9217 4240.6475 1087.2290 1016.1770 1001.6325 0.00014225319 2.03790 12.05241 10.01450 1329643 1418350_at 18 15.0 cM chr18:36665688-36667226 18 B2 chr18:36664585-36675428 18 B2 RSQ Mm.289681 NM_010415 1 1 15200 Hbegf heparin-binding EGF-like growth factor (Hbegf), mRNA. NFAT and Hypertrophy of the heart (Transcription in the broken heart) ErbB signaling pathway;; GnRH signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Cellular Processes; Endocrine System; GnRH signaling pathway [PATH:mmu04912] epidermal growth factor receptor signaling pathway;; extracellular region;; integral to membrane;; membrane;; plasma membrane;; regulation of heart contraction cell;; cell part;; extracellular region cell part;; membrane;; membrane part biological regulation;; cellular process;; multicellular organismal process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process;; regulation of multicellular organismal process;; system process 1007.5777 1032.5526 1000.6996 468.4987 464.5311 493.8675 5.980348e-05 1.09199 9.98516 8.89317 1329700 1418420_at 7 23.5 cM chr7:53633876-53634381 7 B4 chr7:53631843-53634462 7 B4 RSQ Mm.1526 NM_010866 1 1 17927 Myod1 myogenic differentiation 1 (Myod1), mRNA. Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK);; Signal Dependent Regulation of Myogenesis by Corepressor MITR cell differentiation;; DNA binding;; multicellular organismal development;; muscle organ development;; muscle organ development;; myoblast cell fate determination;; myoblast differentiation;; nucleus;; nucleus;; positive regulation of skeletal muscle regeneration;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of alternative nuclear mRNA splicing, via spliceosome;; regulation of alternative nuclear mRNA splicing, via spliceosome;; regulation of transcription;; regulation of transcription, DNA-dependent;; RNA polymerase II transcription factor activity, enhancer binding;; skeletal muscle tissue development;; skeletal muscle tissue development;; skeletal muscle tissue development;; striated muscle cell differentiation;; transcription;; transcription activator activity;; transcription factor activity;; transcription factor binding;; transcription factor complex;; transcription regulator activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; developmental growth;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of growth;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; response to external stimulus;; response to stress 4364.5741 4422.7925 4415.6374 1761.4691 1848.3581 1754.2807 0.00016446847 1.29984 12.10359 10.80375 1329818 1418571_at 17 chr17:23812771-23812982 17 A3.3 chr17:23812411-23814416 17 A3.3 RSQ NM_001161746 2 1 27279 Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), transcript variant 2, mRNA. Cytokine-cytokine receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] angiogenesis;; apoptosis;; cell adhesion;; cell death;; cell differentiation;; cell surface;; integral to membrane;; membrane;; multicellular organismal development;; plasma membrane;; positive regulation of axon extension;; protein binding;; receptor activity;; ruffle;; substrate-bound cell migration, cell attachment to substrate cell;; cell part cell leading edge;; cell part;; cell projection;; cell surface;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; localization;; locomotion;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell death;; cell motility;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; localization of cell;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular component organization;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 3940.8133 4157.4390 4121.4174 1659.0334 1587.8741 1565.2240 2.7583858e-06 1.34451 11.99156 10.64705 1343706 1418572_x_at 17 chr17:23812771-23812982 17 A3.3 chr17:23812411-23814416 17 A3.3 RSQ NM_001161746 2 1 27279 Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), transcript variant 2, mRNA. Cytokine-cytokine receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] angiogenesis;; apoptosis;; cell adhesion;; cell death;; cell differentiation;; cell surface;; integral to membrane;; membrane;; multicellular organismal development;; plasma membrane;; positive regulation of axon extension;; protein binding;; receptor activity;; ruffle;; substrate-bound cell migration, cell attachment to substrate cell;; cell part cell leading edge;; cell part;; cell projection;; cell surface;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity anatomical structure formation;; biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; localization;; locomotion;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell adhesion;; cell death;; cell motility;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; localization of cell;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular component organization;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 32.5977 39.1398 35.6181 16.5060 15.9294 15.0100 0.00081476022 1.17514 5.15727 3.98213 1329858 1418618_at 1 64.1 cM chr1:122499063-122504568 1 E2.3 RSQ Mm.2657 NM_010133 1 1 13798 En1 engrailed 1 (En1), mRNA. DNA binding;; dorsal/ventral pattern formation;; embryonic forelimb morphogenesis;; embryonic limb morphogenesis;; embryonic limb morphogenesis;; hindbrain development;; midbrain development;; midbrain-hindbrain boundary development;; multicellular organismal development;; neuron development;; neuron differentiation;; nucleus;; pigmentation;; proximal/distal pattern formation;; regulation of transcription;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; pigmentation;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1271.6748 1202.1519 1217.2630 379.9297 321.7813 349.3078 0.00047454836 1.81515 10.26445 8.44929 1330049 1418835_at 10 chr10:110945144-110945563 10 D1 chr10:110943341-110945705 10 D1 RSQ Mm.3117 NM_009344 1 1 21664 Phlda1 pleckstrin homology-like domain, family A, member 1 (Phlda1), mRNA. apoptosis;; cytoplasm;; cytoplasmic vesicle;; FasL biosynthetic process;; membrane;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle;; vesicle cellular process;; death;; metabolic process biosynthetic process;; cell death;; cellular metabolic process;; macromolecule metabolic process 130.8503 132.6910 138.7248 41.4607 36.8201 37.5598 0.000105075 1.79752 7.06659 5.26907 1330250 1419086_at 5 chr5:44370129-44370679 5 B3 chr5:44370098-44373001 5 B3 RSQ Mm.46053 NM_008009 1 1 14181 Fgfbp1 fibroblast growth factor binding protein 1 (Fgfbp1), mRNA. extracellular region;; growth factor binding;; membrane;; plasma membrane cell;; cell part;; extracellular region cell part;; membrane binding protein binding 7353.9914 7360.2075 7427.3301 2638.8732 2549.1249 2603.0837 2.2043835e-05 1.50699 12.84949 11.34250 1330359 1419220_at 9 F4 chr9:119923004-119923392 9 F4 UGA Mm.10117 22437 Xirp1 Xin actin binding;; actin cytoskeleton organization;; cardiac muscle cell development;; cell junction;; cell-cell adherens junction;; fascia adherens;; filamin-C binding;; heart morphogenesis;; intercalated disc;; negative regulation of cell proliferation;; protein binding;; regulation of membrane potential;; sarcomere organization cell;; cell part cell part;; membrane;; membrane part binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; cellular component assembly;; cellular component morphogenesis;; cellular developmental process;; cellular homeostasis;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; regulation of biological process;; regulation of biological quality;; regulation of cellular process 239.2075 268.7490 250.1674 123.0307 131.4135 123.0197 0.00018783587 1.00513 7.97966 6.97453 1330567 1419488_at 5 chr5:34839136-34839321 5 B2 chr5:34838744-34856628 5 B2 RSQ Mm.28615 NM_139064 1 1 231130 Tnip2 TNFAIP3 interacting protein 2 (Tnip2), mRNA. cytoplasm;; I-kappaB kinase/NF-kappaB cascade;; protein binding cell;; cell part cell part;; intracellular;; intracellular part binding protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 390.5847 413.3741 403.1652 193.9606 202.7779 200.8954 7.0176325e-06 1.01412 8.65201 7.63789 1330644 1419583_at 11 79.5 cM chr11:118941500-118942031 11 E2 chr11:118938884-118947551 11 E2 RSQ Mm.268070 NM_007625 1 1 12418 RP23-458A23.2 Cbx4 chromobox homolog 4 (Drosophila Pc class) (Cbx4), mRNA. The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails chromatin;; chromatin assembly or disassembly;; chromatin binding;; chromatin modification;; modification-dependent protein catabolic process;; negative regulation of transcription from RNA polymerase II promoter;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; phosphoprotein binding;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; catabolic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 413.1140 357.2566 339.3122 147.2615 147.6943 153.7539 0.0028533279 1.30150 8.52589 7.22440 1331285 1420575_at 8 45.0 cM chr8:96676690-96677865 8 C5 chr8:96676643-96678031 8 C5 RSQ Mm.2064 NM_013603 1 1 17751 Mt3 metallothionein 3 (Mt3), mRNA. cellular metal ion homeostasis;; copper ion binding;; metal ion binding;; negative regulation of neurogenesis;; synaptic vesicle;; zinc ion binding cell;; cell part;; organelle;; synapse;; synapse part cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; synapse part;; synaptic vesicle;; vesicle binding ion binding biological regulation;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; cellular developmental process;; cellular homeostasis;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 181.5268 227.7075 198.9297 97.3248 94.9247 100.2819 0.0057645551 1.04994 7.65706 6.60712 1331459 1420824_at 13 B1 chr13:51796650-51797202 13 A5 UGA Mm.33903 20354 Sema4d Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Sema4d), mRNA Axon guidance CLASS Cellular Processes; Development; Axon guidance [PATH:mmu04360] cell differentiation;; integral to membrane;; membrane;; multicellular organismal development;; nervous system development;; positive regulation of axonogenesis;; positive regulation of axonogenesis;; receptor binding cell;; cell part cell part;; membrane;; membrane part binding protein binding biological regulation;; cellular component organization;; cellular process;; developmental process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular component organization;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process 395.8032 357.7575 342.2051 158.0785 155.9323 135.7749 0.00017844125 1.28528 8.51006 7.22478 1331506 1420884_at 9 chr9:53698088-53701597 9 A5.3 chr9:53698057-53701656 9 A5.3 RSQ Mm.29132 NM_025540 1 1 66402 Sln sarcolipin (Sln), mRNA. enzyme regulator activity;; integral to membrane;; membrane;; sarcoplasmic reticulum cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle enzyme regulator activity 1973.5586 1927.1863 1967.2630 760.4818 719.8664 695.0346 0.00029586937 1.43251 10.93361 9.50110 1331591 1420991_at 19 chr19:36187159-36191361 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1537.9415 1602.5127 1537.0619 543.4858 572.1462 552.3462 1.0349879e-06 1.48770 10.60629 9.11859 1331592 1420992_at 19 chr19:36186663-36186994 19 C2 chr19:36186454-36194334 19 C2 RSQ Mm.10279 NM_013468 1 1 107765 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA. cytoplasm;; I band;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription corepressor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 246.8676 247.9234 243.2141 104.3040 91.4115 99.3919 0.0014329515 1.32447 7.94248 6.61800 1332186 1421830_at 4 47.6 cM chr4:101139016-101139266 4 C6 chr4:101092363-101139600 4 C6 RSQ Mm.42040 NM_009647 2 2 11639 RP23-301M3.3 Ak3l1 adenylate kinase 3-like 1 (Ak3l1), nuclear gene encoding mitochondrial protein, mRNA. Metabolic pathways CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230];; Purine metabolism adenylate kinase activity;; ATP binding;; GTP binding;; kinase activity;; mitochondrion;; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;; nucleobase, nucleoside, nucleotide kinase activity;; nucleotide binding;; nucleotide kinase activity;; phosphotransferase activity, phosphate group as acceptor;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process 63.4071 57.6838 47.4780 20.1484 30.0719 26.7651 0.0074977485 1.14021 5.80195 4.66174 1332410 1422134_at 7 5.0 cM chr7:19888336-19888846 7 A3 chr7:19888044-19895394 7 A3 RSQ Mm.248335 NM_008036 1 1 14282 Fosb FBJ osteosarcoma oncogene B (Fosb), mRNA. FOSB gene expression and drug abuse DNA binding;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 221.6347 221.3106 230.6212 102.9984 109.5603 110.9439 6.0011843e-05 1.05853 7.81045 6.75192 1344583 1422286_a_at 17 chr17:71193992-71194330 17 E1.3 chr17:71193554-71200538 17 E1.3 RSQ Mm.101034 NM_009372 1 1 21815 Tgif1 TGFB-induced factor homeobox 1 (Tgif1), mRNA. chromatin binding;; determination of left/right symmetry;; DNA binding;; dorsal/ventral pattern formation;; JUN kinase binding;; negative regulation of cell proliferation;; negative regulation of retinoic acid receptor signaling pathway;; negative regulation of transcription from RNA polymerase II promoter;; negative regulation of transcription from RNA polymerase II promoter;; neural tube closure;; nucleus;; positive regulation of fibroblast proliferation;; positive regulation of neuron differentiation;; protein binding;; regulation of transcription;; regulation of transcription, DNA-dependent;; retina development in camera-type eye;; sequence-specific DNA binding;; specific transcriptional repressor activity;; transcription;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity chromatin binding;; nucleic acid binding;; protein binding;; transcription factor activity;; transcription repressor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process 431.8676 406.3101 418.1212 166.8186 159.2236 166.4457 2.848699e-06 1.35090 8.70955 7.35865 1332530 1422300_at 11 50.5 cM chr11:89161951-89163873 11 C RSQ Mm.135266 NM_008711 1 1 18121 RP23-205A9.1 Nog noggin (Nog), mRNA. TGF-beta signaling pathway CLASS Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] anatomical structure formation involved in morphogenesis;; anatomical structure formation involved in morphogenesis;; BMP signaling pathway;; brain development;; cartilage development;; cell differentiation;; central nervous system development;; extracellular region;; extracellular space;; mesenchymal cell differentiation;; multicellular organismal development;; negative regulation of cell differentiation;; notochord morphogenesis;; pattern specification process;; positive regulation of epithelial cell proliferation;; positive regulation of epithelial cell proliferation;; prostatic bud formation;; skeletal system development;; ureteric bud development;; urogenital system development extracellular region;; extracellular region part extracellular region part;; extracellular space anatomical structure formation;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell proliferation;; cellular developmental process;; embryonic development;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; reproductive developmental process;; reproductive process 1016.4785 1042.1023 997.3018 491.3976 518.2960 473.5159 0.00018423313 1.04363 9.99218 8.94855 1332719 1422558_at 10 43.0 cM chr10:79721002-79722530 10 C1 chr10:79720895-79723713 10 C1 RSQ Mm.7329 NM_010255 1 1 14431 Gamt guanidinoacetate methyltransferase (Gamt), mRNA. Arginine and proline metabolism;; Glycine, serine and threonine metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Glycine, serine and threonine metabolism [PATH:mmu00260] Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] creatine biosynthetic process;; guanidinoacetate N-methyltransferase activity;; methyltransferase activity;; organ morphogenesis;; regulation of multicellular organism growth;; spermatogenesis;; transferase activity catalytic activity transferase activity biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; gamete generation;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; sexual reproduction 2728.9297 2861.6266 2879.3005 105.0458 103.2849 109.6757 1.9855677e-08 4.73526 11.46275 6.72749 1332723 1422562_at 8 D3 chr8:107152017-107152528 8 D3 UG5 Mm.29467 56437 Rrad Ras-related associated with diabetes (Rrad), mRNA calmodulin binding;; GTP binding;; nucleotide binding;; small GTPase mediated signal transduction binding nucleotide binding;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 254.4957 249.7773 262.9522 60.3312 54.6500 47.9001 0.0011848038 2.24191 7.99822 5.75631 1332965 1422864_at 16 62.2 cM chr16:92603923-92604494 16 C4 chr16:92601710-92826311 16 C4 RSQ Mm.4081 NM_001111022 4 1 12394 Runx1 runt related transcription factor 1 (Runx1), transcript variant 2, mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mmu05220];; Chronic myeloid leukemia;; Pathways in cancer ATP binding;; behavioral response to pain;; central nervous system development;; definitive hemopoiesis;; DNA binding;; embryonic hemopoiesis;; in utero embryonic development;; liver development;; neuron development;; neuron differentiation;; nucleus;; positive regulation of angiogenesis;; protein binding;; regulation of transcription, DNA-dependent;; response to retinoic acid;; skeletal system development;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; multicellular organismal response to stress;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress 72.8341 113.7913 99.7284 25.8690 30.4685 27.2434 0.0061518221 1.75549 6.55224 4.79675 1332966 1422865_at 16 62.2 cM chr16:92601710-92826311 16 C4 RSQ Mm.4081 NM_001111022 4 1 12394 Runx1 runt related transcription factor 1 (Runx1), transcript variant 2, mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mmu05220];; Chronic myeloid leukemia;; Pathways in cancer ATP binding;; behavioral response to pain;; central nervous system development;; definitive hemopoiesis;; DNA binding;; embryonic hemopoiesis;; in utero embryonic development;; liver development;; neuron development;; neuron differentiation;; nucleus;; positive regulation of angiogenesis;; protein binding;; regulation of transcription, DNA-dependent;; response to retinoic acid;; skeletal system development;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; multicellular organismal response to stress;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress 587.2702 627.0421 634.7980 281.4281 320.4872 278.4209 0.00064393953 1.07286 9.26682 8.19396 1333142 1423100_at 12 40.0 cM chr12:86817651-86818190 12 D2 chr12:86814850-86818219 12 D2 RSQ Mm.246513 NM_010234 1 1 14281 Fos FBJ osteosarcoma oncogene (Fos), mRNA. B Cell Survival Pathway;; BCR Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; EGF Signaling Pathway;; EPO Signaling Pathway;; Fc Epsilon Receptor I Signaling in Mast Cells;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 3 signaling pathway;; IL 6 signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; Inhibition of Cellular Proliferation by Gleevec;; Insulin Signaling Pathway;; MAPKinase Signaling Pathway;; METS affect on Macrophage Differentiation;; Nerve growth factor pathway (NGF);; Oxidative Stress Induced Gene Expression Via Nrf2;; PDGF Signaling Pathway;; Pertussis toxin-insensitive CCR5 Signaling in Macrophage;; Repression of Pain Sensation by the Transcriptional Regulator DREAM;; Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy;; Signaling Pathway from G-Protein Families;; T Cell Receptor Signaling Pathway;; Toll-Like Receptor Pathway;; TPO Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell B cell receptor signaling pathway;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Immune System; Toll-like receptor signaling pathway [PATH:mmu04620] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660] Cellular Processes; Immune System; B cell receptor signaling;; MAPK signaling pathway;; Pathways in cancer;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cellular response to extracellular stimulus;; DNA binding;; nervous system development;; nucleus;; nucleus;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein dimerization activity;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; response to drug;; response to protein stimulus;; sequence-specific DNA binding;; transcription factor activity;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to external stimulus 1038.9927 993.4050 1090.4613 297.7718 351.5543 347.0248 0.0003388592 1.65112 10.02264 8.37152 1344806 1423250_a_at 1 101.5 cM chr1:188449250-188454584 1 H5 chr1:188447064-188529871 1 H5 RSQ Mm.18213 NM_009367 1 1 21808 Tgfb2 transforming growth factor, beta 2 (Tgfb2), mRNA. Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Cytokine-cytokine receptor interaction;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; Renal cell carcinoma;; TGF-beta signaling pathway activation-induced cell death of T cells;; axon;; axon guidance;; blood vessel development;; blood vessel remodeling;; cartilage condensation;; cell growth;; cell proliferation;; cell soma;; dopamine biosynthetic process;; extracellular matrix organization;; extracellular region;; extracellular space;; growth;; growth factor activity;; hair follicle development;; hair follicle morphogenesis;; heart development;; hemopoiesis;; induction of apoptosis;; negative regulation of keratinocyte differentiation;; neuron development;; neuron fate commitment;; pathway-restricted SMAD protein phosphorylation;; positive regulation of cell cycle;; protein binding;; regulation of apoptosis;; skeletal system development;; somatic stem cell division;; transforming growth factor beta receptor binding cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell soma;; extracellular region part;; extracellular space binding protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell division;; cell growth;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; extracellular structure organization;; immune system development;; leukocyte homeostasis;; localization of cell;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; tissue remodeling 1152.7744 1257.5812 1188.8881 596.5964 580.2489 557.7999 3.746634e-05 1.05266 10.22758 9.17491 1344811 1423269_a_at 18 chr18:65369304-65372623 18 E1 chr18:65047409-65377480 18 E1 RSQ Mm.98668 NM_001114386 2 1 83814 Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l), transcript variant 1, mRNA. Endocytosis CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144];; Ubiquitin mediated proteolysis acid-amino acid ligase activity;; cytoplasm;; intracellular;; ligase activity;; modification-dependent protein catabolic process;; negative regulation of sodium ion transport;; negative regulation of sodium ion transport;; protein binding;; protein modification process;; sodium channel inhibitor activity cell;; cell part cell part;; intracellular;; intracellular part auxiliary transport protein activity;; binding;; catalytic activity channel regulator activity;; ligase activity;; protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of localization;; transport 573.6519 535.9750 559.6519 247.1863 267.1123 267.9297 3.8365863e-05 1.09399 9.11948 8.02549 1333719 1423835_at 14 A3|14 9.0 cM chr14:22803395-22803774 14 A3 UGA Mm.292401 218820 Zfp503 Zinc finger protein 503 (Zfp503), mRNA intracellular;; metal ion binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 475.5408 438.8135 414.0580 189.3307 207.1326 182.9776 0.00011421326 1.19663 8.78819 7.59157 1333720 1423836_at 14 A3|14 9.0 cM UG5 Mm.292401 218820 Zfp503 Zinc finger protein 503 (Zfp503), mRNA intracellular;; metal ion binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 359.2630 335.4632 318.5213 168.5426 158.8153 173.1870 0.0001476371 1.01660 8.39805 7.38145 1334327 1424615_at 7 E3 chr7:109386887-109386989 7 E3 UGA Mm.302013 233575 Frag1 FGF receptor activating protein 1 (Frag1), mRNA anti-apoptosis;; DNA damage response, signal transduction;; endoplasmic reticulum;; Golgi apparatus;; GPI anchor biosynthetic process;; integral to membrane;; membrane;; nucleus;; protein binding;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell communication;; cell death;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; organophosphate metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 81.1661 92.4310 80.0747 26.0938 29.8064 29.5848 6.7243175e-05 1.56881 6.39880 4.82999 1345166 1424857_a_at 7 chr7:111410157-111410731 7 E3 chr7:111392970-111410753 7 E3 RSQ Mm.326945 NM_030684 1 1 94094 Trim34 tripartite motif-containing 34 (Trim34), mRNA. intracellular;; metal ion binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular binding ion binding;; protein binding 489.8741 531.3741 449.5627 232.4833 188.1905 180.6749 0.0014420368 1.29598 8.93408 7.63809 1334833 1425351_at 2 chr2:151935679-151936227 2 G3 chr2:151931465-151937089 2 G3 RSQ Mm.218639 NM_029688 1 1 76650 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA. antioxidant activity;; ATP binding;; cytoplasm;; cytosol;; magnesium ion binding;; nucleotide binding;; oxidation reduction;; oxidoreductase activity;; response to oxidative stress;; sulfiredoxin activity cell;; cell part cell part;; intracellular;; intracellular part antioxidant activity;; binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity metabolic process;; response to stimulus oxidation reduction;; response to chemical stimulus;; response to stress 2348.5110 2284.7302 2262.4852 476.8720 418.9297 430.5461 0.00023692935 2.38033 11.16634 8.78602 1345965 1426875_s_at 2 chr2:151936530-151936918 2 G3 chr2:151931465-151937089 2 G3 RSQ Mm.218639 NM_029688 1 1 76650 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA. antioxidant activity;; ATP binding;; cytoplasm;; cytosol;; magnesium ion binding;; nucleotide binding;; oxidation reduction;; oxidoreductase activity;; response to oxidative stress;; sulfiredoxin activity cell;; cell part cell part;; intracellular;; intracellular part antioxidant activity;; binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity metabolic process;; response to stimulus oxidation reduction;; response to chemical stimulus;; response to stress 824.8623 881.4139 880.7285 389.4293 438.4977 454.6771 0.0011293588 1.01463 9.75141 8.73678 1335747 1426900_at 10 chr10:66718474-66719018 10 B5.1 chr10:66590005-66719074 10 B5.1 RSQ NM_207221 1 1 108829 Jmjd1c jumonji domain containing 1C (Jmjd1c), mRNA. chromatin modification;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; organelle organization;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 216.9852 218.3053 220.3186 84.5870 97.1554 103.2695 0.0047535397 1.20675 7.77170 6.56495 1336880 1429033_at 6 chr6:28366904-28367275 6 A3.3 chr6:28366690-28371724 6 A3.3 RSQ Mm.332950 NM_028900 1 1 74375 Gcc1 golgi coiled coil 1 (Gcc1), mRNA. cytoplasm;; Golgi apparatus;; membrane cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle 502.5408 505.8241 461.3280 233.3687 203.4130 212.4986 0.00014929678 1.17973 8.93508 7.75535 1346671 1431469_a_at 18 chr18:36018867-36020465 18 B2 chr18:35989471-36021342 18 B2 RSQ Mm.94560 NM_133687 1 1 67393 Cxxc5 CXXC finger 5 (Cxxc5), mRNA. cytoplasm;; DNA binding;; metal ion binding;; nucleus;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding 548.4110 562.9852 567.2907 173.7850 186.0676 176.3957 2.30732e-05 1.64683 9.12800 7.48117 1337282 1433575_at 13 chr13:29041009-29041491 13 A3.1 UGA Mm.455819 Transcribed locus, strongly similar to NP_033264.2 SRY-box containing gene 4 [Mus musculus] 964.1025 891.5964 967.6248 264.1499 251.8186 260.8223 2.3955037e-05 1.86107 9.87720 8.01613 1337418 1434025_at 14 chr14:99713709-99714191 14 E2.2 UGA Mm.441332 Transcribed locus 533.5974 489.0088 539.4488 247.8597 273.8260 249.0817 9.6503627e-05 1.01923 9.02289 8.00366 1347098 1434773_a_at 4 52.0 cM chr4:118809715-118809927 4 D2.1 chr4:118781349-118809935 4 D2.1 RSQ Mm.21002 NM_011400 1 1 20525 RP23-344D2.2 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1), mRNA. Vitamin C in the Brain Adipocytokine signaling pathway;; Pathways in cancer;; Renal cell carcinoma CLASS Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Renal cell carcinoma [PATH:mmu05211] basolateral plasma membrane;; carbohydrate transport;; cytoplasm;; glucose transmembrane transporter activity;; glucose transport;; integral to membrane;; intracellular;; membrane;; plasma membrane;; protein binding;; substrate-specific transmembrane transporter activity;; sugar:hydrogen symporter activity;; transmembrane transport;; transport;; transporter activity cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part binding;; transporter activity protein binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization establishment of localization;; transmembrane transport;; transport 3396.0841 3344.4747 3253.4297 607.3380 666.1293 620.1634 2.7791841e-05 2.40082 11.70166 9.30084 1347930 1438855_x_at 12 56.0 cM chr12:112692993-112693192 12 F1 IPA Tnfaip2 tumor necrosis factor, alpha-induced protein 2 1031.9227 1059.9033 1031.4726 475.4297 411.3906 424.1817 0.0018142312 1.25511 10.02378 8.76866 1338758 1448199_at 8 chr8:11611781-11612172 8 A1.1 chr8:11611582-11635689 8 A1.1 RSQ Mm.12459 NM_133971 1 1 102334 Ankrd10 ankyrin repeat domain 10 (Ankrd10), mRNA. 4229.9804 4101.1907 3888.3464 751.5744 789.5818 784.9710 3.6690976e-06 2.39266 11.99107 9.59840 1338812 1448272_at 1 71.0 cM chr1:135972093-135972484 1 E4 chr1:135971441-135975732 1 E4 RSQ Mm.392646 NM_007570 1 1 12227 Btg2 B-cell translocation gene 2, anti-proliferative (Btg2), mRNA. BTG family proteins and cell cycle regulation anterior/posterior pattern formation;; negative regulation of apoptosis;; neuron differentiation;; protein amino acid methylation;; protein binding;; regulation of transcription, DNA-dependent;; response to DNA damage stimulus;; transcription binding protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell death;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to stress 29.7899 26.8275 42.2828 14.7072 17.4374 16.3057 0.026008643 1.00484 5.01480 4.00996 1348199 1448301_s_at 13 12.0 cM chr13:32933960-32943054 13 A3.2 RSQ Mm.20144 NM_025429 1 1 66222 RP23-427P14.4 Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a (Serpinb1a), mRNA. cytoplasm;; endopeptidase inhibitor activity;; regulation of protein catabolic process;; serine-type endopeptidase inhibitor activity cell;; cell part cell part;; intracellular;; intracellular part enzyme regulator activity enzyme inhibitor activity biological regulation;; metabolic process;; regulation of biological process catabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of metabolic process 639.9896 589.0408 676.0721 170.9235 152.1751 144.0514 3.8538861e-05 2.02931 9.30839 7.27908 1338857 1448328_at 5 chr5:34905699-34906233 5 B2 chr5:34892336-34906288 5 B2 RSQ Mm.5012 NM_001136088 4 1 24055 Sh3bp2 SH3-domain binding protein 2 (Sh3bp2), transcript variant d, mRNA. Natural killer cell mediated cytotoxicity CLASS Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] protein binding;; SH3 domain binding binding protein binding 1709.4891 1715.6037 1689.0408 665.8675 653.2635 647.8035 9.7302368e-07 1.37860 10.73528 9.35668 1339017 1448529_at 2 84.0 cM chr2:148230231-148230761 2 G3 chr2:148230206-148233924 2 G3 RSQ Mm.24096 NM_009378 1 1 21824 RP23-70N3.2 Thbd thrombomodulin (Thbd), mRNA. Complement and coagulation cascades CLASS Cellular Processes; Immune System; Complement and coagulation cascades [PATH:mmu04610] binding;; blood coagulation;; calcium ion binding;; embryonic development;; female pregnancy;; integral to membrane;; membrane;; negative regulation of coagulation;; plasma membrane;; receptor activity cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity ion binding;; signal transducer activity biological regulation;; developmental process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus coagulation;; embryonic development;; female pregnancy;; multicellular organismal development;; negative regulation of biological process;; negative regulation of multicellular organismal process;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of multicellular organismal process;; reproductive process;; response to external stimulus;; response to stress 774.6110 780.8944 781.1279 415.2784 347.3741 359.5941 0.0053735501 1.06241 9.60524 8.54284 1339375 1448960_at 18 chr18:36020796-36021211 18 B2 chr18:35989471-36021342 18 B2 RSQ Mm.94560 NM_133687 1 1 67393 Cxxc5 CXXC finger 5 (Cxxc5), mRNA. cytoplasm;; DNA binding;; metal ion binding;; nucleus;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding 5293.7720 5588.1837 5506.6385 2723.6911 2687.9347 2686.9769 0.00022463556 1.01660 12.41507 11.39847 1339463 1449073_at 6 8.5 cM chr6:29411311-29411636 6 A3.3 chr6:29383152-29411888 6 A3.3 RSQ Mm.39046 NM_001081185 1 1 68794 Flnc filamin C, gamma (Flnc), mRNA. Focal adhesion CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510];; MAPK signaling pathway actin binding;; actin cytoskeleton;; actin filament-based process;; cytoplasm;; cytoskeleton;; membrane;; muscle fiber development cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; non-membrane-bounded organelle binding protein binding cellular process;; developmental process;; multicellular organismal process actin filament-based process;; anatomical structure development;; cellular developmental process;; multicellular organismal development 780.2635 668.3992 692.9613 215.9840 229.7588 214.4440 0.00026700885 1.69527 9.47634 7.78107 1339561 1449188_at 10 chr10:79620535-79621046 10 C1 chr10:79611034-79621112 10 C1 RSQ Mm.143813 NM_021565 1 1 59090 Midn midnolin (Midn), mRNA. nucleolus;; nucleus cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part 2059.0425 2041.1732 1989.7122 432.2075 397.1113 428.8662 5.2881311e-05 2.27597 10.98709 8.71112 1339701 1449363_at 1 103.2 cM chr1:192994277-192994768 1 H6 chr1:192994174-193007212 1 H6 RSQ Mm.2706 NM_007498 1 1 11910 Atf3 activating transcription factor 3 (Atf3), mRNA. DNA binding;; gluconeogenesis;; nucleus;; protein dimerization activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex;; transcription repressor activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 793.5231 775.6884 828.7525 316.7158 339.4873 360.0368 0.00024107726 1.24000 9.64209 8.40209 1339763 1449433_at 11 B5 chr11:72985602-72986081 11 B4 UGA Mm.156893 94045 RP23-263M10.2 P2rx5 Purinergic receptor P2X, ligand-gated ion channel, 5 (P2rx5), mRNA Calcium signaling pathway;; Neuroactive ligand-receptor interaction CLASS Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] ATP-gated cation channel activity;; cell surface receptor linked signal transduction;; integral to membrane;; integral to plasma membrane;; ion channel activity;; ion transport;; receptor activity;; transport cell;; cell part cell part;; membrane;; membrane part molecular transducer activity;; transporter activity signal transducer activity;; substrate-specific transporter activity;; transmembrane transporter activity biological regulation;; cellular process;; establishment of localization;; localization;; regulation of biological process cell communication;; establishment of localization;; regulation of biological process;; regulation of cellular process;; transport 1441.2160 1450.5048 1459.3252 700.1195 685.0384 707.7250 2.7471763e-05 1.05598 10.50217 9.44618 1339832 1449519_at 6 chr6:66985453-66985671 6 C1 chr6:66985089-66987401 6 C1 RSQ Mm.389750 NM_007836 1 1 13197 Gadd45a growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), mRNA. ATM Signaling Pathway;; Cell Cycle: G2/M Checkpoint;; p53 Signaling Pathway Cell cycle;; MAPK signaling pathway;; p53 signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Cell cycle [PATH:mmu04110] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] cell cycle;; cell cycle arrest;; centrosome cycle;; negative regulation of protein kinase activity;; nucleus;; protein binding;; regulation of cell cycle;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding biological regulation;; cellular component organization;; cellular process;; metabolic process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cellular metabolic process;; microtubule-based process;; organelle organization;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function;; response to stress 884.7538 894.2427 905.2729 446.4948 424.1280 432.2580 5.2937483e-05 1.04309 9.80529 8.76220 1348500 1449852_a_at 2 chr2:119915222-119980311 2 E5 RSQ Mm.132226 NM_133838 1 1 98878 RP23-348L16.8 Ehd4 EH-domain containing 4 (Ehd4), mRNA. Endocytosis CLASS Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] ATP binding;; calcium ion binding;; endosome;; GTP binding;; GTPase activity;; membrane;; nucleotide binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; ion binding;; nucleoside binding;; nucleotide binding 40.5499 57.1793 33.6230 18.7394 19.8731 17.0824 0.025739684 1.20508 5.41681 4.21173 1340126 1449984_at 5 E1|5 51.0 cM UGA Mm.4979 20310 Cxcl2 Chemokine (C-X-C motif) ligand 2 (Cxcl2), mRNA Chemokine signaling pathway CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062];; Cytokine-cytokine receptor interaction chemokine activity;; chemotaxis;; cytokine activity;; extracellular region;; extracellular space;; immune response;; inflammatory response extracellular region;; extracellular region part extracellular region part;; extracellular space binding protein binding immune system process;; locomotion;; response to stimulus behavior;; immune response;; response to chemical stimulus;; response to external stimulus;; response to stress;; taxis 405.0296 451.2680 397.8170 157.1633 164.0247 167.1677 0.0003165689 1.35888 8.70523 7.34635 1348663 1450387_s_at 4 47.6 cM chr4:101139123-101139504 4 C6 chr4:101092363-101139600 4 C6 RSQ Mm.42040 NM_009647 2 2 11639 RP23-301M3.3 Ak3l1 adenylate kinase 3-like 1 (Ak3l1), nuclear gene encoding mitochondrial protein, mRNA. Metabolic pathways CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230];; Purine metabolism adenylate kinase activity;; ATP binding;; GTP binding;; kinase activity;; mitochondrion;; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;; nucleobase, nucleoside, nucleotide kinase activity;; nucleotide binding;; nucleotide kinase activity;; phosphotransferase activity, phosphate group as acceptor;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process 213.8440 205.5096 223.6587 122.2039 95.8878 83.7410 0.016438732 1.10812 7.74288 6.63476 1340425 1450413_at 15 46.8 cM chr15:79826303-79845238 15 E1 RSQ Mm.144089 NM_011057 1 1 18591 Pdgfb platelet derived growth factor, B polypeptide (Pdgfb), mRNA. Transcriptional activation of dbpb from mRNA Cytokine-cytokine receptor interaction;; Focal adhesion;; Gap junction;; Glioma;; MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Com;; Pathways in cancer;; Prostate cancer;; Regulation of actin cytoskeleton;; Renal cell carcinoma actin cytoskeleton organization;; branching involved in salivary gland morphogenesis;; cell projection assembly;; cell proliferation;; collagen binding;; epithelial cell proliferation involved in salivary gland morphogenesis;; extracellular region;; growth factor activity;; membrane;; negative regulation of cell migration;; positive regulation of endothelial cell proliferation;; positive regulation of fibroblast growth factor receptor signaling pathway;; regulation of peptidyl-tyrosine phosphorylation;; substrate-bound cell migration cell;; cell part;; extracellular region cell part;; membrane binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cell projection organization;; cell proliferation;; cellular component assembly;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion;; regulation of metabolic process 714.1649 737.7814 749.2230 267.9678 265.8354 292.3871 0.0001379455 1.41479 9.51880 8.10401 1340426 1450414_at 15 46.8 cM chr15:79826551-79826877 15 E1 chr15:79826303-79845238 15 E1 RSQ Mm.144089 NM_011057 1 1 18591 Pdgfb platelet derived growth factor, B polypeptide (Pdgfb), mRNA. Transcriptional activation of dbpb from mRNA Cytokine-cytokine receptor interaction;; Focal adhesion;; Gap junction;; Glioma;; MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Cellular Processes; Cell Com;; Pathways in cancer;; Prostate cancer;; Regulation of actin cytoskeleton;; Renal cell carcinoma actin cytoskeleton organization;; branching involved in salivary gland morphogenesis;; cell projection assembly;; cell proliferation;; collagen binding;; epithelial cell proliferation involved in salivary gland morphogenesis;; extracellular region;; growth factor activity;; membrane;; negative regulation of cell migration;; positive regulation of endothelial cell proliferation;; positive regulation of fibroblast growth factor receptor signaling pathway;; regulation of peptidyl-tyrosine phosphorylation;; substrate-bound cell migration cell;; cell part;; extracellular region cell part;; membrane binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process actin filament-based process;; anatomical structure development;; anatomical structure morphogenesis;; cell communication;; cell motility;; cell motion;; cell projection organization;; cell proliferation;; cellular component assembly;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion;; regulation of metabolic process 358.2277 371.8831 344.6403 119.9162 129.2152 95.1542 0.0044750247 1.65356 8.48413 6.83057 1340635 1450698_at 2 chr2:127163556-127163826 2 F1 chr2:127161894-127164113 2 F1 RSQ Mm.4729 NM_010090 1 1 13537 RP23-206D14.6 Dusp2 dual specificity phosphatase 2 (Dusp2), mRNA. Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] dephosphorylation;; hydrolase activity;; MAP kinase tyrosine/serine/threonine phosphatase activity;; mitogen-activated protein kinase binding;; nucleus;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 1411.9536 1425.8560 1435.1444 514.0150 493.8949 460.5803 0.00071785787 1.54234 10.47602 8.93368 1340651 1450716_at 16 53.4 cM chr16:85794592-85794942 16 C3.3 chr16:85794071-85803360 16 C3.3 RSQ Mm.1421 NM_009621 1 1 11504 Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), mRNA. basement membrane;; cytoplasmic vesicle;; extracellular matrix;; extracellular region;; heart trabecula formation;; heparin binding;; hydrolase activity;; kidney development;; metal ion binding;; metalloendopeptidase activity;; metalloendopeptidase activity;; metalloendopeptidase activity;; metallopeptidase activity;; negative regulation of angiogenesis;; ovulation from ovarian follicle;; peptidase activity;; protein binding;; proteinaceous extracellular matrix;; proteolysis;; zinc ion binding cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular matrix;; extracellular matrix part;; extracellular region part;; intracellular;; intracellular organelle;; intracellular part;; vesicle binding;; catalytic activity carbohydrate binding;; hydrolase activity;; ion binding;; pattern binding;; protein binding anatomical structure formation;; biological regulation;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; rhythmic process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; catabolic process;; gamete generation;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of developmental process;; ovulation cycle;; ovulation cycle process;; primary metabolic process;; regulation of biological process;; regulation of developmental process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; sexual reproduction 647.2192 579.5104 701.8720 198.7296 227.3866 220.6812 0.00016277372 1.57413 9.32396 7.74983 1348775 1450826_a_at 7 23.5 cM chr7:53967388-53967984 7 B4 chr7:53967367-53971046 7 B4 RSQ Mm.14277 NM_011315 1 1 20210 Saa3 serum amyloid A 3 (Saa3), mRNA. acute-phase response;; extracellular region;; high-density lipoprotein particle extracellular region;; extracellular region part;; macromolecular complex extracellular region part;; extracellular space;; plasma lipoprotein particle;; protein-lipid complex response to stimulus response to external stimulus;; response to stress 627.2333 643.6571 628.5221 146.3624 186.1569 160.6176 0.0023764862 1.95252 9.30628 7.35375 1348802 1450922_a_at 1 101.5 cM chr1:188448391-188448651 1 H5 chr1:188447064-188529871 1 H5 RSQ Mm.18213 NM_009367 1 1 21808 Tgfb2 transforming growth factor, beta 2 (Tgfb2), mRNA. Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Cytokine-cytokine receptor interaction;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; Renal cell carcinoma;; TGF-beta signaling pathway activation-induced cell death of T cells;; axon;; axon guidance;; blood vessel development;; blood vessel remodeling;; cartilage condensation;; cell growth;; cell proliferation;; cell soma;; dopamine biosynthetic process;; extracellular matrix organization;; extracellular region;; extracellular space;; growth;; growth factor activity;; hair follicle development;; hair follicle morphogenesis;; heart development;; hemopoiesis;; induction of apoptosis;; negative regulation of keratinocyte differentiation;; neuron development;; neuron fate commitment;; pathway-restricted SMAD protein phosphorylation;; positive regulation of cell cycle;; protein binding;; regulation of apoptosis;; skeletal system development;; somatic stem cell division;; transforming growth factor beta receptor binding cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell soma;; extracellular region part;; extracellular space binding protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell division;; cell growth;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; extracellular structure organization;; immune system development;; leukocyte homeostasis;; localization of cell;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; tissue remodeling 301.1696 351.7740 350.3053 142.8969 148.5418 142.5996 0.0022720152 1.20534 8.38180 7.17646 1340805 1450923_at 1 101.5 cM chr1:188447467-188447940 1 H5 chr1:188447064-188529871 1 H5 RSQ Mm.18213 NM_009367 1 1 21808 Tgfb2 transforming growth factor, beta 2 (Tgfb2), mRNA. Cell cycle;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Cytokine-cytokine receptor interaction;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; Renal cell carcinoma;; TGF-beta signaling pathway activation-induced cell death of T cells;; axon;; axon guidance;; blood vessel development;; blood vessel remodeling;; cartilage condensation;; cell growth;; cell proliferation;; cell soma;; dopamine biosynthetic process;; extracellular matrix organization;; extracellular region;; extracellular space;; growth;; growth factor activity;; hair follicle development;; hair follicle morphogenesis;; heart development;; hemopoiesis;; induction of apoptosis;; negative regulation of keratinocyte differentiation;; neuron development;; neuron fate commitment;; pathway-restricted SMAD protein phosphorylation;; positive regulation of cell cycle;; protein binding;; regulation of apoptosis;; skeletal system development;; somatic stem cell division;; transforming growth factor beta receptor binding cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell soma;; extracellular region part;; extracellular space binding protein binding biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell division;; cell growth;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; extracellular structure organization;; immune system development;; leukocyte homeostasis;; localization of cell;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of multicellular organismal process;; tissue remodeling 1911.5043 1968.7630 1895.6206 646.5049 652.4852 628.8909 2.7207662e-07 1.58301 10.91067 9.32766 1348818 1451021_a_at 14 chr14:99701186-99702697 14 E2.2 chr14:99697909-99712631 14 E2.2 RSQ Mm.30262 NM_009769 1 1 12224 Klf5 Kruppel-like factor 5 (Klf5), mRNA. angiogenesis;; DNA binding;; DNA binding;; intracellular;; metal ion binding;; microvillus assembly;; nucleic acid binding;; nucleus;; positive regulation of transcription;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell projection organization;; cellular component assembly;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1140.7718 1061.0782 1070.2930 496.5102 551.8252 539.2844 0.00010612585 1.04408 10.09030 9.04622 1341053 1451264_at 12 chr12:72002571-72003037 12 C3 chr12:71926500-72003221 12 C3 RSQ Mm.2962 NM_028127 1 1 319710 Frmd6 FERM domain containing 6 (Frmd6), mRNA. binding;; cytoplasm;; cytoskeleton;; membrane;; plasma membrane cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; non-membrane-bounded organelle binding 130.0492 131.6540 106.4405 51.8906 62.8610 64.9589 0.001874415 1.03483 6.93248 5.89765 1341254 1451538_at 11 69.5 cM chr11:112646659-112647196 11 E2 chr11:112643523-112649071 11 E2 RSQ Mm.286407 NM_011448 1 1 20682 RP23-36D5.1 Sox9 SRY-box containing gene 9 (Sox9), mRNA. cartilage condensation;; cartilage development;; cell differentiation;; cell fate commitment;; cell fate specification;; DNA binding;; endochondral bone morphogenesis;; epithelial cell proliferation involved in prostatic bud elongation;; epithelial to mesenchymal transition;; hair follicle development;; heart development;; male germ-line sex determination;; male gonad development;; male sex determination;; negative regulation of bone mineralization;; negative regulation of chondrocyte differentiation;; negative regulation of transcription, DNA-dependent;; neural crest cell development;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; prostate gland morphogenesis;; protein binding;; regulation of apoptosis;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription activator activity;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription activator activity;; transcription factor activity biological adhesion;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell death;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; cellular metabolic process;; developmental growth;; macromolecule metabolic process;; molting cycle;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; negative regulation of multicellular organismal process;; nitrogen compound metabolic process;; ossification;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; reproductive developmental process;; reproductive process;; tissue remodeling 491.4297 469.7440 450.4501 200.9062 245.3227 241.3579 0.0033544025 1.04262 8.87727 7.83465 1341305 1451612_at 8 C5|8 45.0 cM chr8:96703143-96703979 8 C5 UGA Mm.192991 17748 Mt1 Metallothionein 1, mRNA (cDNA clone MGC:47147 IMAGE:4990006) cellular metal ion homeostasis;; cellular zinc ion homeostasis;; copper ion binding;; cytosol;; detoxification of copper ion;; lysosome;; metal ion binding;; nitric oxide mediated signal transduction;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; response to chemical stimulus 403.4822 430.6428 413.8841 206.4480 192.5464 205.5454 2.0637005e-05 1.04593 8.69993 7.65400 1341319 1451634_at 17 7.36 cM chr17:13007636-13008080 17 A1 chr17:12934176-13008423 17 A1 RSQ NR_002853 2 1 104103 Airn antisense Igf2r RNA (Airn), transcript variant 1, non-coding RNA. genetic imprinting biological regulation;; cellular process;; metabolic process;; regulation of biological process cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of metabolic process 4180.2906 4203.4998 4195.7075 981.1130 911.4083 951.8186 0.00019136524 2.14556 12.03382 9.88826 1341347 1451680_at 2 chr2:151935283-151935614 2 G3 chr2:151931465-151937089 2 G3 RSQ Mm.218639 NM_029688 1 1 76650 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1), mRNA. antioxidant activity;; ATP binding;; cytoplasm;; cytosol;; magnesium ion binding;; nucleotide binding;; oxidation reduction;; oxidoreductase activity;; response to oxidative stress;; sulfiredoxin activity cell;; cell part cell part;; intracellular;; intracellular part antioxidant activity;; binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity metabolic process;; response to stimulus oxidation reduction;; response to chemical stimulus;; response to stress 94.6380 103.1296 95.0330 37.4327 42.5624 46.4850 0.0017335194 1.21553 6.60767 5.39214 1342006 1452677_at 11 A4 UGA Mm.211131 71701 RP23-313I4.2 Pnpt1 Polynucleotide phosphorylase-like protein (PNPASE gene) Purine metabolism;; Pyrimidine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] mitochondrial intermembrane space cell;; cell part;; envelope;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle envelope;; organelle envelope lumen;; organelle part 3532.9631 3291.2873 3378.5646 758.4727 901.1034 879.0435 0.00041270776 2.01033 11.73110 9.72076 1349775 1455899_x_at 11 chr11:117827463-117827587 11 E2 chr11:117827392-117830476 11 E2 RSQ Mm.3468 NM_007707 1 1 12702 RP23-268N22.6 Socs3 suppressor of cytokine signaling 3 (Socs3), mRNA. IL-2 Receptor Beta Chain in T cell Activation;; IL22 Soluble Receptor Signaling Pathway Adipocytokine signaling pathway;; Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Cellular Processes; Endocrin;; Ubiquitin mediated proteolysis branching involved in embryonic placenta morphogenesis;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of insulin receptor signaling pathway;; negative regulation of signal transduction;; placenta blood vessel development;; positive regulation of cell differentiation;; positive regulation of cell differentiation;; protein binding;; regulation of cell differentiation;; regulation of cell differentiation;; regulation of growth;; regulation of protein amino acid phosphorylation;; spongiotrophoblast differentiation;; spongiotrophoblast differentiation;; trophoblast giant cell differentiation;; trophoblast giant cell differentiation binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of metabolic process;; regulation of response to stimulus;; response to chemical stimulus;; response to endogenous stimulus 2547.2819 2516.3176 2565.6128 501.8186 599.3431 644.3749 0.0023894031 2.13564 11.31231 9.17667 1349871 1456212_x_at 11 E2 chr11:117827490-117827770 11 E2 IPA Mm.3468 Socs3 Suppressor of cytokine signaling 3 (Socs3), mRNA 2130.3466 1995.0602 1993.9678 718.2331 749.8354 693.5062 5.0450845e-06 1.50134 10.99351 9.49217 1343080 1460700_at 11 60.5 cM chr11:100748149-100748711 11 D chr11:100748123-100800825 11 D RSQ Mm.249934 NM_011486 3 1 20848 RP23-279L23.5 Stat3 signal transducer and activator of transcription 3 (Stat3), transcript variant 3, mRNA. EGF Signaling Pathway;; Erk1/Erk2 Mapk Signaling pathway;; IL 6 signaling pathway;; IL22 Soluble Receptor Signaling Pathway;; PDGF Signaling Pathway;; Role of ERBB2 in Signal Transduction and Oncology;; Signaling of Hepatocyte Growth Factor Receptor;; Stat3 Signaling Pathway;; TPO Signaling Pathway Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200];; Adipocytokine signaling pathway;; Chemokine signaling pathway;; Jak-STAT signaling pathway;; Pancreatic cancer;; Pathways in cancer acute-phase response;; calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; DNA binding;; eating behavior;; eye photoreceptor cell differentiation;; glucose homeostasis;; JAK-STAT cascade involved in growth hormone signaling pathway;; nucleus;; plasma membrane;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; protein dimerization activity;; protein kinase binding;; regulation of multicellular organism growth;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; sexual reproduction;; signal transducer activity;; signal transduction;; temperature homeostasis;; transcription;; transcription activator activity;; transcription factor activity;; transcription from RNA polymerase II promoter cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cell communication;; cellular developmental process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to endogenous stimulus;; response to external stimulus;; response to stress;; sexual reproduction;; temperature homeostasis 326.7330 293.5599 317.4286 153.1382 148.9297 128.5013 0.00078448096 1.12565 8.28659 7.16094 1370785 1419985_s_at 11 28.5 cM chr11:54863346-54863586 11 B1.3 chr11:54863239-54891633 11 B1.3 RSQ Mm.22361 NM_177471 1 1 52570 Ccdc69 coiled-coil domain containing 69 (Ccdc69), mRNA. 491.9852 522.7671 497.5964 170.5748 171.2306 166.8491 3.3345994e-05 1.57162 8.97711 7.40549 1370826 1428420_a_at 12 chr12:112667670-112669350 12 F1 chr12:112655640-112669394 12 F1 RSQ Mm.248640 NM_028807 1 1 74190 1200009I06Rik RIKEN cDNA 1200009I06 gene (1200009I06Rik), mRNA. 149.7921 171.9226 159.7830 9.9889 10.1801 12.0198 9.9526366e-06 3.90568 7.32413 3.41845 1350626 1428663_at 3 chr3:131021980-131022466 3 G3 chr3:131021902-131047841 3 G3 RSQ Mm.273360 NM_028943 1 1 74442 Sgms2 sphingomyelin synthase 2 (Sgms2), mRNA. Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide cholinephosphotransferase activity;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; integral to plasma membrane;; kinase activity;; lipid metabolic process;; membrane;; plasma membrane;; sphingolipid metabolic process;; sphingomyelin biosynthetic process;; sphingomyelin synthase activity;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; organophosphate metabolic process;; primary metabolic process 176.0733 163.8612 185.4764 75.5555 59.0052 64.4003 0.0013729606 1.40674 7.45048 6.04374 1350856 1429029_at 3 G3 chr3:131025716-131026224 3 G3 UGA Mm.273360 74442 Sgms2 Sphingomyelin synthase 2 (Sgms2), mRNA Metabolic pathways CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu00600];; Sphingolipid metabolism ceramide cholinephosphotransferase activity;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; integral to plasma membrane;; kinase activity;; lipid metabolic process;; membrane;; plasma membrane;; sphingolipid metabolic process;; sphingomyelin biosynthetic process;; sphingomyelin synthase activity;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; organophosphate metabolic process;; primary metabolic process 490.1945 545.4885 531.4098 275.6434 242.9132 238.5964 0.00036228827 1.05097 9.02743 7.97646 1351042 1429304_at 8 A1.1 chr8:11614351-11614743 8 A1.1 UGA Mm.12459 102334 Ankrd10 Ankyrin repeat domain 10 (Ankrd10), mRNA 678.4476 670.4325 601.6635 295.5887 322.3900 337.6717 0.00019853219 1.02942 9.34262 8.31320 1370950 1430584_s_at 3 A2|3 11.7 cM chr3:14865376-14865506 3 A1 UGA Mm.300 12350 Car3 Carbonic anhydrase 3, mRNA (cDNA clone MGC:18583 IMAGE:4195712) Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] carbonate dehydratase activity;; cytoplasm;; lyase activity;; metal ion binding;; nickel ion binding;; one-carbon metabolic process;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 383.6388 365.6560 313.3908 102.3978 157.1999 115.8699 0.0057903404 1.51964 8.46326 6.94362 1352101 1430702_at 15 chr15:98590670-98590993 15 F1 chr15:98590568-98592483 15 F1 RSQ Mm.441883 NM_175232 1 1 76061 5830427D03Rik RIKEN cDNA 5830427D03 gene (5830427D03Rik), mRNA. 366.4738 387.5431 410.2278 186.7610 154.8753 176.1028 0.00072131513 1.17192 8.59869 7.42676 1353535 1432787_at 5 chr5:15476262-15476595 5 A2 UGA Mm.446079 Transcribed locus 480.9297 406.7912 408.0565 253.5099 189.5964 197.6784 0.0050071183 1.02359 8.75015 7.72657 1353754 1433023_at chr12:82344479-82345008 12 D1 IPA 2310068G24Rik RIKEN cDNA 2310068G24 gene 378.8243 386.7983 360.1435 114.3324 125.0738 123.1345 9.921624e-06 1.63514 8.55108 6.91594 1353838 1433110_at chr1:21942230-21942722 1 A4 IPA 5830474E16Rik RIKEN cDNA 5830474E16 gene 676.2764 650.8316 622.3986 329.7820 301.6641 325.4220 4.8594683e-05 1.02699 9.34310 8.31611 1354264 1433742_at 19 chr19:25508401-25508603 19 B chr19:25311691-25508986 19 B RSQ Mm.260722 NM_181404 1 1 107351 Kank1 KN motif and ankyrin repeat domains 1 (Kank1), mRNA. negative regulation of actin filament polymerization anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cellular component assembly;; cellular macromolecular complex subunit organization;; cellular metabolic process;; macromolecular complex subunit organization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of metabolic process;; organelle organization;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of cellular component biogenesis;; regulation of cellular component organization;; regulation of cellular process;; regulation of metabolic process 178.0881 205.8361 191.7651 90.9325 93.0366 79.5979 0.00029536582 1.12796 7.58167 6.45370 1355094 1435284_at 11 chr11:29596168-29596644 11 A3.3 UGA Mm.440639 Transcribed locus 931.9759 886.6027 838.7075 353.2630 358.3860 351.4852 0.00077102793 1.32034 9.78944 8.46910 1355281 1435585_at X F1 chrX:132760192-132760615 X F1 UGA Mm.18125 100040972 RP23-105O4.2 RP23-105O4.2 Transcription elongation factor A (SII)-like 7 (Tceal7), mRNA 138.7144 159.2392 161.6378 70.2057 78.0851 67.6771 0.00034066396 1.08885 7.25588 6.16703 1355674 1436196_at 11 chr11:23637084-23637417 11 A3.2 UGA Mm.30811 Transcribed locus 190.8741 164.4699 176.2763 71.2665 72.2493 67.3830 0.00035675111 1.33182 7.46662 6.13479 1355677 1436200_at X A2 chrX:33906277-33906788 X A3.3 UGA Mm.327654 74365 RP23-145O4.1 Lonrf3 LON peptidase N-terminal domain and ring finger 3, mRNA (cDNA clone MGC:155927 IMAGE:40129613) ATP-dependent peptidase activity;; binding;; metal ion binding;; protein binding;; proteolysis;; zinc ion binding binding;; catalytic activity hydrolase activity;; ion binding;; protein binding metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 37.6151 41.8791 37.5185 16.9192 17.1773 20.3450 0.0009857253 1.10710 5.28364 4.17654 1371257 1436203_a_at 15 chr15:55468259-55468349 15 D1 UGA Mm.478132 Transcribed locus 338.4798 390.2439 380.8212 109.5856 124.5128 112.6363 4.2752459e-05 1.67751 8.52804 6.85053 1356231 1437199_at 19 D2 chr19:53615956-53616474 19 D2 UGA Mm.52043 240672 Dusp5 Dual specificity phosphatase 5 (Dusp5), mRNA MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] hydrolase activity;; MAP kinase tyrosine/serine/threonine phosphatase activity catalytic activity hydrolase activity 456.9299 401.8184 460.9338 210.9452 215.6551 196.2728 0.0003745741 1.08154 8.77821 7.69667 1356245 1437224_at 11 chr11:29606699-29607240 11 A3.3 chr11:29593773-29642916 11 A3.3 RSQ Mm.192580 NM_194051 2 1 68585 RP23-176O5.4 Rtn4 reticulon 4 (Rtn4), transcript variant 5, mRNA. angiogenesis;; cell projection;; cell soma;; endoplasmic reticulum;; integral to endoplasmic reticulum membrane;; integral to membrane;; membrane;; negative regulation of anti-apoptosis;; negative regulation of axon extension;; nervous system development;; nuclear envelope;; regulation of cell migration cell;; cell part;; envelope;; organelle;; organelle part cell part;; cell projection;; cell soma;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part anatomical structure formation;; biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; localization;; locomotion;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell death;; cell motility;; cell motion;; cell projection organization;; cellular component morphogenesis;; cellular developmental process;; localization of cell;; multicellular organismal development;; negative regulation of anti-apoptosis;; negative regulation of biological process;; negative regulation of cellular component organization;; negative regulation of cellular process;; negative regulation of developmental process;; regulation of anti-apoptosis;; regulation of biological process;; regulation of cellular component organization;; regulation of cellular process;; regulation of developmental process;; regulation of localization;; regulation of locomotion;; regulation of multicellular organismal process 82.1644 66.3981 73.2373 21.0455 23.2087 25.8606 0.00017817943 1.66110 6.20267 4.54157 1356563 1437833_at 19 B|19 2.0 cM chr19:5752075-5752356 19 A UG5 Mm.182396 16998 Ltbp3 Latent transforming growth factor beta binding protein 3 (Ltbp3), mRNA binding;; calcium ion binding;; extracellular region;; growth factor binding;; proteinaceous extracellular matrix;; skeletal system development;; transforming growth factor beta receptor signaling pathway;; transforming growth factor beta receptor signaling pathway extracellular region;; extracellular region part extracellular matrix;; extracellular region part binding ion binding;; protein binding biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 149.0140 185.8659 189.3443 58.7507 54.4041 47.5234 0.00036038435 1.70318 7.44076 5.73758 1356745 1438185_at 7 chr7:83378532-83379004 7 D2 UGA Mm.370825 Transcribed locus 885.8741 970.5680 947.4409 305.2089 321.3774 304.7462 1.9923455e-05 1.58943 9.86718 8.27775 1356892 1438429_at 8 chr8:11622380-11622942 8 A1.1 UGA Mm.441154 Transcribed locus 205.9640 186.2001 225.0207 26.6215 29.4348 26.4638 2.8753541e-05 2.90032 7.68029 4.77997 1357431 1439412_at chr9:112004583-112004658 9 F3 IPA ESTs 35.6331 50.8499 44.9737 23.5011 20.2428 19.3242 0.0076961979 1.04933 5.43811 4.38878 1357586 1439638_at 13 chr13:104615681-104616180 13 D1 UGA Mm.442245 Transcribed locus 734.1372 741.5407 600.4444 301.3544 327.6984 269.4208 0.00085030006 1.20631 9.42806 8.22175 1371475 1439740_s_at 1 H2.3 chr1:169153282-169153392 1 H2.3 UGA Mm.440156 80914 Uck2 Uridine-cytidine kinase 2, mRNA (cDNA clone IMAGE:3493906) Drug metabolism - other enzymes;; Metabolic pathways CLASS Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] Metabolism; Xenobiotics Biodegradation and Metabolism; Drug metabolism - other enzymes [PATH:mmu00983];; Pyrimidine metabolism ATP binding;; kinase activity;; metabolic process;; nucleotide binding;; phosphotransferase activity, alcohol group as acceptor;; transferase activity;; uridine kinase activity binding;; catalytic activity nucleoside binding;; nucleotide binding;; transferase activity metabolic process 305.5309 299.4029 318.1556 81.3517 88.1226 64.1841 0.0036812118 1.99434 8.26490 6.27056 1357961 1440051_at IPA Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230017C05 product:hypothetical protein, full insert sequence. 124.9121 111.1290 85.0647 43.9675 52.0680 31.6576 0.0085701466 1.34206 6.72378 5.38172 1358405 1440543_at 12 C1 chr12:53010825-53011204 12 C1 UGA Mm.131941 320487 Heatr5a HEAT repeat containing 5A, mRNA (cDNA clone MGC:99412 IMAGE:30544145) 403.3556 533.3844 408.7996 139.3842 134.4529 127.6467 0.0034324399 1.73343 8.79673 7.06330 1358631 1440776_at 5 C3.1 chr5:67139353-67139604 5 C3.1 UGA Mm.374778 77569 Limch1 LIM and calponin homology domains 1 (Limch1), mRNA actin binding;; actomyosin structure organization;; metal ion binding;; zinc ion binding binding ion binding;; protein binding cellular component organization;; cellular process actin filament-based process;; organelle organization 96.5529 96.5024 103.6766 48.9456 42.3024 37.2512 0.0052217353 1.21557 6.62723 5.41166 1358691 1440878_at 16 62.2 cM chr16:92601752-92602086 16 C4 chr16:92601710-92826311 16 C4 RSQ Mm.4081 NM_001111022 4 1 12394 Runx1 runt related transcription factor 1 (Runx1), transcript variant 2, mRNA. Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mmu05220];; Chronic myeloid leukemia;; Pathways in cancer ATP binding;; behavioral response to pain;; central nervous system development;; definitive hemopoiesis;; DNA binding;; embryonic hemopoiesis;; in utero embryonic development;; liver development;; neuron development;; neuron differentiation;; nucleus;; positive regulation of angiogenesis;; protein binding;; regulation of transcription, DNA-dependent;; response to retinoic acid;; skeletal system development;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; nucleoside binding;; nucleotide binding;; protein binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; behavior;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; multicellular organismal response to stress;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress 63.4025 82.1758 77.4065 25.8771 30.6025 32.7379 0.0010150046 1.31981 6.20716 4.88736 1358927 1441129_at 5 chr5:93535215-93535741 5 E2 UGA Mm.450589 Transcribed locus 350.0812 335.9187 360.3314 88.8867 95.1042 102.5755 0.00012154726 1.87027 8.44556 6.57529 1359131 1441360_at chrX:155711702-155712021 X F4 IPA ESTs, Moderately similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus] 110.9231 122.6275 113.0433 47.6703 30.3079 37.7028 0.010339424 1.60635 6.85076 5.24441 1359142 1441372_at 18 chr18:68108128-68108625 18 E2 UGA Mm.446015 Transcribed locus 86.6902 102.3660 115.2089 50.1883 44.1120 48.4722 0.0045901448 1.08401 6.65450 5.57049 1359292 1441529_at chr11:22757572-22758125 11 A3.2 IPA ESTs 239.3613 262.9002 207.8978 141.0580 105.6996 109.1112 0.0047006166 1.00251 7.88038 6.87788 1359309 1441546_at 6 chr6:50063213-50063735 6 B2.3 chr6:50060284-50063960 6 B2.3 RSQ XM_898388 1 1 624524 LOC624524 PREDICTED: hypothetical LOC624524 (LOC624524), mRNA. 157.2023 157.9271 156.1753 65.0842 60.3673 62.0749 0.00044383037 1.33025 7.29554 5.96529 1359586 1441858_at IPA Unknown 65.5719 61.6627 60.3553 31.5659 29.0734 29.8183 3.0628319e-05 1.05223 5.96558 4.91335 1371720 1441956_s_at 5 G2|5 78.0 cM chr5:136958783-136958847 5 G2 UGA Mm.320317 13047 Cux1 CDNA fis, clone TRACH2005314,highly similar to Mus musculus mCASP (cux) mRNA auditory receptor cell differentiation;; chromatin binding;; DNA binding;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; intra-Golgi vesicle-mediated transport;; lung development;; membrane;; multicellular organismal development;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; regulation of transcription;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription regulator activity;; transcription repressor activity;; transport cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; transcription regulator activity chromatin binding;; nucleic acid binding;; transcription factor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport;; vesicle-mediated transport 304.1689 325.3140 353.0964 117.4413 129.7672 139.3029 0.00015988895 1.34689 8.35278 7.00589 1359813 1442176_at 10 chr10:67558667-67559135 10 B5.1 chr10:67558340-67741474 10 B5.1 RSQ Mm.440357 NM_023598 1 1 71371 Arid5b AT rich interactive domain 5B (MRF1-like) (Arid5b), mRNA. DNA binding;; face morphogenesis;; fibroblast migration;; intracellular;; kidney development;; multicellular organism growth;; muscle organ morphogenesis;; nitrogen compound metabolic process;; nucleus;; palate development;; platelet-derived growth factor receptor signaling pathway;; post-embryonic development;; regulation of transcription, DNA-dependent;; skeletal system morphogenesis;; transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleic acid binding biological regulation;; cellular process;; developmental process;; growth;; localization;; locomotion;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell communication;; cell motility;; cell motion;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; nitrogen compound metabolic process;; post-embryonic development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 140.4297 115.5820 141.8017 62.5478 64.1097 52.2731 0.00099793405 1.15228 7.04474 5.89245 1359876 1442241_at 5 chr5:23092186-23092646 5 A3 UGA Mm.443009 Transcribed locus 486.8951 448.0872 449.9860 175.8048 169.7432 170.8648 0.00015481333 1.42236 8.84961 7.42725 1359922 1442288_at 11 B1.3|11 29.5 cM chr11:54844602-54845026 11 B1.3 UGA Mm.265347 11749 Anxa6 Annexin A6, mRNA (cDNA clone MGC:6574 IMAGE:3482035) calcium ion binding;; calcium ion transport;; calcium-dependent phospholipid binding;; cytoplasm;; perinuclear region of cytoplasm;; regulation of muscle contraction cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; lipid binding biological regulation;; establishment of localization;; localization;; multicellular organismal process;; regulation of biological process establishment of localization;; regulation of biological process;; regulation of multicellular organismal process;; system process;; transport 352.1864 379.1085 349.1038 195.0077 170.2395 171.1519 0.00057391541 1.01208 8.49139 7.47931 1360008 1442382_at 13 D1 chr13:103559646-103562570 13 D1 UGA Mm.202606 328329 Mast4 MKIAA0303 protein ATP binding;; cytoplasm;; kinase activity;; magnesium ion binding;; metal ion binding;; nucleotide binding;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein serine/threonine kinase activity;; transferase activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 635.3268 556.4423 554.1874 321.3202 260.5442 255.1722 0.0022810332 1.06570 9.18189 8.11619 1360020 1442395_at 1 chr1:34085393-34085906 1 B UGA Mm.436779 Transcribed locus 810.7263 796.9055 809.7142 293.4851 260.3700 269.9265 0.00084820962 1.55487 9.65420 8.09933 1360303 1442700_at 4 C6|4 46.8 cM chr4:102243528-102243998 4 C6 UGA Mm.20181 18578 RP23-57D24.1 Pde4b Phosphodiesterase 4B, cAMP specific, mRNA (cDNA clone IMAGE:5354427) Purine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] 3',5'-cyclic-AMP phosphodiesterase activity;; smooth muscle contraction catalytic activity hydrolase activity multicellular organismal process system process 254.5513 247.0487 248.1182 121.4411 111.2129 112.5854 0.00043542331 1.11973 7.96512 6.84539 1360318 1442715_at X UGA Mm.411941 Transcribed locus 190.0408 204.3828 202.6011 107.9015 95.2722 94.8209 0.00061963892 1.00437 7.63593 6.63156 1371742 1442760_x_at chr11:29616149-29616353 11 A3.3 IPA ESTs 236.1724 255.5325 243.2201 74.6728 81.5836 88.4012 0.00035384654 1.58949 7.93573 6.34624 1360727 1443159_at 10 C1 chr10:82357178-82357468 10 C1 UGA Mm.210155 50493 Txnrd1 Thioredoxin reductase 1, mRNA (cDNA clone MGC:46868 IMAGE:5059831) Pyrimidine metabolism CLASS Metabolism; Nucleotide Metabolism; Pyrimidine metabolism [PATH:mmu00240] cell proliferation;; cell redox homeostasis;; cytoplasm;; cytosol;; FAD binding;; gastrulation;; mesoderm formation;; NADP or NADPH binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; selenium binding;; thioredoxin-disulfide reductase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle antioxidant activity;; binding;; catalytic activity cofactor binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity;; selenium binding;; thioredoxin-disulfide reductase activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell proliferation;; cellular homeostasis;; embryonic development;; multicellular organismal development;; oxidation reduction;; regulation of biological process;; regulation of biological quality;; regulation of cellular process 85.4342 95.8322 90.8806 30.7800 35.1871 39.0084 0.0013118075 1.37949 6.50169 5.12220 1360780 1443212_at chr8:75853675-75854162 8 B3.3 IPA ESTs 1352.6141 1341.0749 1312.3666 428.6160 422.2975 401.8301 2.4878516e-05 1.67752 10.38289 8.70537 1360866 1443299_at 8 B1.1 chr8:46988445-46988717 8 B1.1 UGA Mm.282900 53318 Pdlim3 PDZ and LIM domain 3 (Pdlim3), mRNA actin cytoskeleton;; actin filament organization;; cytoplasm;; cytoskeletal protein binding;; heart development;; metal ion binding;; protein binding;; skeletal muscle tissue development;; structural constituent of muscle;; structural constituent of muscle;; Z disc;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; structural molecule activity ion binding;; protein binding;; structural constituent of muscle cellular component organization;; cellular process;; developmental process;; multicellular organismal process actin filament-based process;; anatomical structure development;; multicellular organismal development;; organelle organization 119.9270 158.5883 164.7428 63.1307 63.1218 61.4676 0.013071255 1.22571 7.19308 5.96736 1361083 1443544_at chr18:68137416-68137770 18 E2 IPA ESTs 74.4958 82.3863 65.4243 30.3315 29.3568 31.1417 0.0036311845 1.28534 6.20506 4.91972 1361128 1443593_at chr16:22134185-22134615 16 B1 IPA Mus musculus 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430085A14 product:unknown EST, full insert sequence. 69.8172 64.1338 70.7098 17.5608 19.8101 22.6311 0.0010639951 1.77656 6.09079 4.31423 1361161 1443630_at chr3:136399370-136399659 3 G3 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 144.7766 153.0817 115.2967 59.1054 67.2717 60.6281 0.004789761 1.13533 7.09502 5.95969 1362068 1444645_at 11 chr11:20451270-20451705 11 A3.1 UG5 Mm.449965 Transcribed locus 100.3992 94.9140 98.7907 46.6336 43.6106 52.9237 0.0035587419 1.04290 6.61482 5.57191 1362606 1445200_at chr14:121449800-121450181 14 E5 IPA ESTs, Moderately similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 351.0118 343.7526 347.9196 157.5952 129.5364 127.2414 0.0051336055 1.33816 8.44107 7.10291 1362800 1445398_at 5 chr5:67306909-67307387 5 C3.1 UGA Mm.454791 Transcribed locus 386.1633 352.0731 311.2328 119.4993 130.6484 133.8825 0.00063755744 1.44647 8.44488 6.99841 1363243 1445866_at chr13:103556977-103557456 13 D1 IPA ESTs 449.1228 455.1874 446.7451 217.0408 195.7547 231.9444 0.0040070201 1.07074 8.81486 7.74412 1363341 1445966_at 17 chr17:12945147-12945628 17 A1 UGA Mm.411497 Transcribed locus 435.5323 428.8620 401.3469 92.5009 122.8117 102.5630 0.0018178174 2.00255 8.71990 6.71736 1363514 1446141_at chr1:188503427-188503922 1 H5 IPA Mus musculus 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130049J04 product:unclassifiable, full insert sequence. 55.0511 66.3343 56.0986 24.3339 23.4325 21.8537 0.0007432016 1.34638 5.88142 4.53505 1363581 1446212_at chr1:21847057-21847588 1 A4 IPA Mus musculus 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430057L14 product:unknown EST, full insert sequence. 107.6002 111.5327 116.1609 40.3370 41.1548 38.6118 4.896334e-06 1.48095 6.80361 5.32266 1363593 1446224_at 19 C2 chr19:36665196-36665583 19 C2 UGA Mm.61107 226098 Hectd2 HECT domain containing 2, mRNA (cDNA clone MGC:178371 IMAGE:9053363) acid-amino acid ligase activity;; intracellular;; ligase activity;; modification-dependent protein catabolic process;; protein modification process cell;; cell part cell part;; intracellular catalytic activity ligase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 680.0408 669.7630 722.5169 304.6117 274.9567 298.4341 4.7433607e-05 1.23957 9.43129 8.19172 1363692 1446324_at 5 chr5:15445246-15445625 5 A2 UGA Mm.445336 Transcribed locus 174.1644 194.5886 170.9723 93.4229 81.1616 93.6470 0.0004055767 1.00954 7.48874 6.47920 1363903 1446537_at IPA ESTs 288.3186 271.1169 286.9852 110.9322 102.4294 101.5482 2.2494128e-05 1.42703 8.13971 6.71268 1364275 1446921_at 11 chr11:11901351-11901733 11 A1 UGA Mm.438641 Transcribed locus 3872.9896 3869.2951 3842.8185 1616.6509 1907.4264 1945.8741 0.0059477434 1.08754 11.91501 10.82747 1364970 1447891_at IPA Unknown 484.8186 501.9665 493.2433 137.2189 154.7326 165.5505 0.0016305843 1.69794 8.94630 7.24837 1365310 1453119_at 2 chr2:19581695-19582189 2 A3 UGA Mm.470264 Transcribed locus 78.5470 90.8349 74.9660 36.2054 41.7512 37.5504 0.00073185285 1.07873 6.34294 5.26421 1365458 1453323_at 9 chr9:112138041-112138459 9 F3 chr9:112136775-112138524 9 F3 RSQ XM_001478934 1 1 331033 2900079G21Rik PREDICTED: RIKEN cDNA 2900079G21 gene (2900079G21Rik), mRNA. 136.7060 136.9914 131.1691 60.9511 61.6777 59.4235 2.8346846e-06 1.15298 7.07605 5.92307 1365662 1453595_at IPA 2900064B18Rik RIKEN cDNA 2900064B18 gene 324.1517 317.4300 324.7969 157.3879 157.2841 146.3491 0.00043425806 1.06851 8.33140 7.26289 1366506 1454799_at 5 E4 chr5:101327556-101328077 5 E4 UGA Mm.271911 231510 Agpat9 1-acylglycerol-3-phosphate O-acyltransferase 9, mRNA (cDNA clone MGC:169852 IMAGE:8861247) acyltransferase activity;; endoplasmic reticulum;; glycerol-3-phosphate O-acyltransferase activity;; integral to membrane;; membrane;; metabolic process;; phospholipid biosynthetic process;; transferase activity;; triglyceride biosynthetic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; organic ether metabolic process;; organophosphate metabolic process;; primary metabolic process 1427.8668 1434.6579 1327.5698 580.7016 576.4393 541.0930 1.282291e-05 1.30277 10.44690 9.14414 1372358 1455157_a_at 8 chr8:125005638-125005952 8 E1 chr8:125005196-125075229 8 E1 RSQ XM_001481316 1 1 234839 BC039210 PREDICTED: cDNA sequence BC039210 (BC039210), mRNA. 59.5033 50.0037 53.2814 26.4679 26.5642 24.0971 0.0006290584 1.07535 5.75814 4.68279 1366906 1455468_at 7 chr7:36470549-36470974 7 B2 chr7:36470518-36539473 7 B2 RSQ Mm.257808 NM_178704 1 1 233115 Dpy19l3 dpy-19-like 3 (C. elegans) (Dpy19l3), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 818.7012 769.6025 721.9888 307.8794 293.9297 334.8463 6.8992687e-05 1.30270 9.58700 8.28430 1367261 1456139_at chr17:12960003-12960449 17 A1 IPA Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130073E08 product:unknown EST, full insert sequence. 41.0669 66.6873 54.4917 18.7084 22.4825 22.8474 0.011713048 1.31897 5.72907 4.41010 1367837 1457018_at 14 A3 chr14:24240872-24241001 14 A3 UGA Mm.343607 16531 Kcnma1 Calcium-activated potassium channel SLO1 mRNA, complete cds, alternatively spliced Vascular smooth muscle contraction CLASS Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] adult walking behavior;; apical plasma membrane;; auditory receptor cell differentiation;; binding;; calcium ion binding;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; calcium-activated potassium channel activity;; catalytic activity;; cell maturation;; circadian rhythm;; cytoplasmic part;; endoplasmic reticulum;; external side of plasma membrane;; eye blink reflex;; integral to membrane;; integral to membrane;; ion channel activity;; ion transport;; large conductance calcium-activated potassium channel activity;; large conductance calcium-activated potassium channel activity;; locomotor rhythm;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; micturition;; negative regulation of cell volume;; neuromuscular process controlling balance;; plasma membrane;; postsynaptic membrane;; potassium channel activity;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; protein homooligomerization;; regulation of action potential in neuron;; regulation of aldosterone metabolic process;; regulation of membrane potential;; regulation of membrane potential;; relaxation of vascular smooth muscle;; response to hypoxia;; saliva secretion;; sensory perception of sound;; sensory perception of sound;; smooth muscle contraction involved in micturition;; synaptic transmission;; terminal button;; transport;; vasodilation;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex;; organelle;; synapse;; synapse part apical part of cell;; cell part;; cell projection;; cell projection part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; postsynaptic membrane;; protein complex;; synapse part binding;; catalytic activity;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus;; rhythmic process adult behavior;; anatomical structure development;; behavior;; biosynthetic process;; cell communication;; cellular component assembly;; cellular developmental process;; cellular homeostasis;; cellular metabolic process;; circadian rhythm;; developmental maturation;; digestion;; establishment of localization;; hormone metabolic process;; macromolecular complex subunit organization;; multicellular organismal development;; negative regulation of biological process;; negative regulation of multicellular organismal process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress;; rhythmic behavior;; system process;; transport 710.9297 660.0291 684.7195 287.0627 299.5895 275.0964 1.3914879e-05 1.25449 9.41977 8.16529 1368145 1457356_at 17 chr17:12946045-12946480 17 A1 UGA Mm.411497 Transcribed locus 387.0921 359.7645 320.9852 151.6204 144.5705 138.5039 0.00083524509 1.29336 8.47127 7.17791 1368162 1457374_at 18 E1 chr18:65329357-65329745 18 E1 UGA Mm.98668 83814 Nedd4l Neural precursor cell expressed, developmentally down-regulated gene 4-like, mRNA (cDNA clone MGC:49433 IMAGE:3157137) Endocytosis CLASS Genetic Information Processing; Folding, Sorting and Degradation; Ubiquitin mediated proteolysis [PATH:mmu04120] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144];; Ubiquitin mediated proteolysis acid-amino acid ligase activity;; cytoplasm;; intracellular;; ligase activity;; modification-dependent protein catabolic process;; negative regulation of sodium ion transport;; negative regulation of sodium ion transport;; protein binding;; protein modification process;; sodium channel inhibitor activity cell;; cell part cell part;; intracellular;; intracellular part auxiliary transport protein activity;; binding;; catalytic activity channel regulator activity;; ligase activity;; protein binding biological regulation;; cellular process;; establishment of localization;; localization;; metabolic process;; negative regulation of biological process;; regulation of biological process catabolic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of transport;; primary metabolic process;; regulation of biological process;; regulation of localization;; transport 62.6033 66.3902 71.1858 31.2947 29.0169 32.4858 0.00011180791 1.10873 6.05819 4.94947 1368397 1457637_at 15 chr15:93423954-93424139 15 E3 UGA Mm.447383 Transcribed locus 30.2738 34.9679 41.9520 15.6410 16.8742 18.9736 0.0053905563 1.04957 5.14621 4.09664 1372499 1457656_s_at 17 chr17:51896651-51896813 17 C UGA Mm.477120 Transcribed locus 112.8032 138.9829 132.2151 52.2279 58.2650 59.5010 0.0009163979 1.17234 6.99439 5.82205 1368615 1457898_at 1 chr1:21809222-21809675 1 A4 UGA Mm.434527 Transcribed locus 68.5118 85.7406 86.4653 23.0482 31.0767 25.8177 0.00073303954 1.59320 6.31808 4.72488 1368821 1458115_at 8 chr8:64401070-64401578 8 B3.1 UGA Mm.440931 Transcribed locus 213.3292 205.3803 219.3551 66.6755 70.5184 69.2101 1.8675773e-06 1.62810 7.73207 6.10397 1368884 1458179_at chr17:12967927-12968457 17 A1 IPA ESTs 64.2993 73.0743 76.9292 39.6953 29.6983 33.5145 0.0033343944 1.06452 6.15449 5.08997 1369097 1458432_at 1 chr1:43511003-43511494 1 B UG5 Mm.447891 Transcribed locus 305.6319 320.9574 325.0850 153.9128 139.1235 142.0834 0.00010971041 1.12993 8.30885 7.17893 1369597 1458947_at chr13:63347049-63347523 13 B3 IPA ESTs 683.1283 722.5378 673.8883 206.0403 213.7492 200.2739 2.1476956e-06 1.74564 9.43644 7.69080 1369653 1459003_at X A6-A7.1 chrX:54043834-54044264 X A5 UGA Mm.3126 14199 RP23-71G11.1 Fhl1 Four and a half LIM domains 1, mRNA (cDNA clone MGC:32284 IMAGE:5012394) cell differentiation;; cytoplasm;; metal ion binding;; multicellular organismal development;; nucleus;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding cellular process;; developmental process;; multicellular organismal process cellular developmental process;; multicellular organismal development 115.0192 101.7045 109.4645 51.1925 57.0026 46.6056 0.0010158188 1.07835 6.76276 5.68442 1369844 1459205_at chr7:88577467-88577894 7 D3 IPA ESTs 366.7719 358.6909 391.7159 90.3209 103.9826 83.6722 0.00053431965 2.01171 8.53967 6.52795 1370044 1459409_at chr10:59030775-59031053 10 B4 IPA Mus musculus adult male cecum cDNA, RIKEN full-length enriched library, clone:9130014A12 product:unclassifiable, full insert sequence. 73.2407 96.3366 95.0563 37.5792 42.5913 43.5559 0.0049276594 1.08872 6.45177 5.36305 1370101 1459467_at chr14:25054971-25055453 14 A3 IPA ESTs 129.3122 96.7926 116.4645 37.1947 35.8740 34.4233 0.0033867023 1.66269 6.82509 5.16240 1370104 1459470_at chr16:92615772-92616302 16 C4 IPA ESTs