A 1 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen A 2 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen A 3 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen B 4 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen B 5 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen B 6 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen The input data set contained 45101 genes The filtered output data set contains 130 genes 36365 gene rows removed by Include where A-B T-test p-value (two tailed) <= 0.05 8606 gene rows removed by Include where A-B Mean Difference <= -1 A A A B B B 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen A-B p-Value A-B Mean Difference A Mean B Mean Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 127.4476 134.5965 133.5763 329.8339 245.4086 368.3903 0.017924848 -1.23398 7.04259 8.27658 1327621 1415823_at 19 C3|19 43.0 cM chr19:44379503-44380037 19 C3 UG5 Mm.477490 20250 Scd2 Fatty acid desaturase (Scd3) Biosynthesis of unsaturated fatty acids;; PPAR signaling pathway CLASS Metabolism; Lipid Metabolism; Biosynthesis of unsaturated fatty acids [PATH:mmu01040] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] endoplasmic reticulum;; fatty acid biosynthetic process;; integral to membrane;; iron ion binding;; lipid biosynthetic process;; lipid metabolic process;; membrane;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;; stearoyl-CoA 9-desaturase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; oxidation reduction;; primary metabolic process 109.5534 108.8453 81.1374 350.2630 290.2975 369.8186 0.00086884444 -1.76015 6.62797 8.38812 1327622 1415824_at 19 43.0 cM chr19:44377854-44378358 19 C3 chr19:44368165-44381354 19 C3 RSQ Mm.477490 NM_009128 1 1 20250 Scd2 stearoyl-Coenzyme A desaturase 2 (Scd2), mRNA. Biosynthesis of unsaturated fatty acids;; PPAR signaling pathway CLASS Metabolism; Lipid Metabolism; Biosynthesis of unsaturated fatty acids [PATH:mmu01040] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] endoplasmic reticulum;; fatty acid biosynthetic process;; integral to membrane;; iron ion binding;; lipid biosynthetic process;; lipid metabolic process;; membrane;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;; stearoyl-CoA 9-desaturase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; oxidation reduction;; primary metabolic process 251.0264 256.1806 254.3658 637.3946 542.8403 551.2780 0.0035071278 -1.18120 7.98782 9.16902 1327729 1415971_at 10 22.0 cM chr10:36854908-36855205 10 B1 chr10:36853048-36858732 10 B1 RSQ Mm.477725 NM_008538 1 1 17118 Marcks myristoylated alanine rich protein kinase C substrate (Marcks), mRNA. Effects of calcineurin in Keratinocyte Differentiation actin binding;; calmodulin binding;; cell cortex;; centrosome;; cytoplasm;; cytoskeleton;; germinal vesicle;; membrane;; protein kinase C binding cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding protein binding 173.2686 165.9393 167.2719 368.5746 295.4993 383.2267 0.010798742 -1.03915 7.39914 8.43829 1327861 1416147_at 11 29.0 cM chr11:53073951-53074494 11 B1.3 chr11:53073315-53113981 11 B1.3 RSQ Mm.239865 NM_008300 1 1 15525 RP23-337J7.3 Hspa4 heat shock protein 4 (Hspa4), mRNA. Antigen processing and presentation CLASS Environmental Information Processing; Membrane Transport; Pores ion channels Cellular Processes; Immune System; Antigen processing and presentation [PATH:mmu04612] ATP binding;; cytoplasm;; nucleotide binding;; response to stress cell;; cell part cell part;; intracellular;; intracellular part binding nucleoside binding;; nucleotide binding response to stimulus response to stress 191.8662 214.7191 201.0615 435.0964 555.8798 471.5711 0.002204768 -1.26113 7.66059 8.92172 1343325 1416514_a_at 5 86.0 cM chr5:143722033-143734868 5 G2 RSQ Mm.289707 NM_007984 1 1 14086 Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1), mRNA. actin binding;; actin filament binding;; filopodium;; protein binding, bridging cell;; cell part cell part;; cell projection binding protein binding 58.1149 67.8136 74.3360 124.4942 175.2179 152.0450 0.0037455593 -1.16699 6.05344 7.22043 1328142 1416515_at 5 86.0 cM chr5:143731618-143733619 5 G2 chr5:143722033-143734868 5 G2 RSQ Mm.289707 NM_007984 1 1 14086 Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1), mRNA. actin binding;; actin filament binding;; filopodium;; protein binding, bridging cell;; cell part cell part;; cell projection binding protein binding 123.7982 124.1524 117.2949 215.7185 258.5713 302.3976 0.014218672 -1.07531 6.92727 8.00258 1328185 1416564_at 14 C3 chr14:64569018-64569492 14 D1 UGA Mm.42162 20680 Sox7 SRY-box containing gene 7 (Sox7), mRNA DNA binding;; nucleus;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 109.5986 114.2619 116.4307 270.3911 201.6884 249.4264 0.011016504 -1.07392 6.82520 7.89912 1328664 1417163_at 1 chr1:185898879-185899173 1 H5 chr1:185858339-185899515 1 H5 RSQ Mm.404024 NM_022019 1 1 63953 Dusp10 dual specificity phosphatase 10 (Dusp10), mRNA. MAPK signaling pathway CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] cytoplasm;; dephosphorylation;; hydrolase activity;; MAP kinase tyrosine/serine/threonine phosphatase activity;; nucleus;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 141.3951 136.9296 125.7281 327.0306 551.5224 735.4410 0.028053415 -1.92266 7.07168 8.99434 1328866 1417403_at 3 chr3:129337407-129337843 3 G3 chr3:129235303-129341413 3 G3 RSQ Mm.314113 NM_130450 1 1 170439 Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) (Elovl6), mRNA. Biosynthesis of unsaturated fatty acids CLASS Metabolism; Lipid Metabolism; Biosynthesis of unsaturated fatty acids [PATH:mmu01040] endoplasmic reticulum;; fatty acid biosynthetic process;; fatty acid elongation;; integral to endoplasmic reticulum membrane;; integral to membrane;; lipid biosynthetic process;; membrane;; mitochondrion;; transferase activity, transferring acyl groups other than amino-acyl groups cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 202.0844 199.0892 197.3741 600.9026 708.1519 1092.3741 0.016719341 -1.95709 7.64029 9.59738 1328867 1417404_at 3 chr3:129340915-129341301 3 G3 chr3:129235303-129341413 3 G3 RSQ Mm.314113 NM_130450 1 1 170439 Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) (Elovl6), mRNA. Biosynthesis of unsaturated fatty acids CLASS Metabolism; Lipid Metabolism; Biosynthesis of unsaturated fatty acids [PATH:mmu01040] endoplasmic reticulum;; fatty acid biosynthetic process;; fatty acid elongation;; integral to endoplasmic reticulum membrane;; integral to membrane;; lipid biosynthetic process;; membrane;; mitochondrion;; transferase activity, transferring acyl groups other than amino-acyl groups cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 342.7886 346.2920 353.7801 852.4274 647.2951 700.3186 0.011237348 -1.06728 8.44124 9.50853 1328897 1417439_at 19 chr19:5070090-5070618 19 A chr19:5068077-5070640 19 A RSQ Mm.29597 NM_054042 1 1 70445 Cd248 CD248 antigen, endosialin (Cd248), mRNA. binding;; calcium ion binding;; cytoplasm;; integral to membrane;; membrane;; plasma membrane;; sugar binding cell;; cell part cell part;; intracellular;; intracellular part;; membrane;; membrane part binding carbohydrate binding;; ion binding 555.8741 541.4600 496.5945 891.2093 1085.3978 1454.5039 0.02881953 -1.07823 9.05175 10.12998 1329001 1417561_at 7 4.0 cM chr7:20277334-20277835 7 A3 chr7:20274829-20278007 7 A3 RSQ Mm.182440 NM_001110009 2 1 11812 Apoc1 apolipoprotein C-I (Apoc1), transcript variant 2, mRNA. cholesterol metabolic process;; extracellular region;; lipid transport;; lipoprotein metabolic process;; transport;; triglyceride metabolic process;; very-low-density lipoprotein particle extracellular region;; extracellular region part;; macromolecular complex extracellular region part;; extracellular space;; plasma lipoprotein particle;; protein-lipid complex cellular process;; establishment of localization;; localization;; metabolic process alcohol metabolic process;; biosynthetic process;; cellular metabolic process;; establishment of localization;; macromolecule metabolic process;; organic ether metabolic process;; primary metabolic process;; transport 178.5692 173.6488 176.8683 290.4721 451.9635 485.1519 0.036152453 -1.17924 7.46230 8.64154 1329842 1418601_at 19 20.0 cM chr19:20767471-20767872 19 B chr19:20767442-20802046 19 B RSQ Mm.14609 NM_011921 1 1 26358 Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 (Aldh1a7), mRNA. Metabolic pathways CLASS Metabolism; Metabolism of Cofactors and Vitamins; Retinol metabolism [PATH:mmu00830];; Retinol metabolism aldehyde dehydrogenase (NAD) activity;; cytoplasm;; metabolic process;; oxidation reduction;; oxidoreductase activity;; retinal metabolic process;; retinoic acid metabolic process cell;; cell part cell part;; intracellular;; intracellular part catalytic activity oxidoreductase activity biological regulation;; cellular process;; metabolic process cellular metabolic process;; hormone metabolic process;; oxidation reduction;; primary metabolic process;; regulation of biological quality;; secondary metabolic process 57.2328 44.4773 51.5856 86.7933 157.9122 145.1077 0.027489775 -1.30694 5.66756 6.97449 1330128 1418937_at 12 chr12:91963030-91963530 12 D3 chr12:91962991-91976878 12 D3 RSQ Mm.21389 NM_010050 1 1 13371 Dio2 deiodinase, iodothyronine, type II (Dio2), mRNA. hormone biosynthetic process;; integral to membrane;; membrane;; oxidation reduction;; oxidoreductase activity;; selenium binding;; thyroid hormone catabolic process;; thyroxine 5'-deiodinase activity cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity oxidoreductase activity;; selenium binding biological regulation;; cellular process;; metabolic process biosynthetic process;; catabolic process;; cellular metabolic process;; hormone metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process;; regulation of biological quality 713.0390 677.1720 651.1900 2091.5578 2143.0032 2260.8741 5.8370473e-06 -1.67010 9.40938 11.07948 1330167 1418982_at 7 12.0 cM chr7:35906421-35906839 7 B1 chr7:35904311-35906947 7 B1 RSQ Mm.349667 NM_007678 1 1 12606 Cebpa CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa), mRNA. Keratinocyte Differentiation;; MAPKinase Signaling Pathway Acute myeloid leukemia CLASS Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221];; Pathways in cancer brown fat cell differentiation;; cell maturation;; cytokine-mediated signaling pathway;; DNA binding;; embryonic placenta development;; fat cell differentiation;; liver development;; lung development;; macrophage differentiation;; mitochondrion organization;; myeloid cell differentiation;; negative regulation of cell proliferation;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; positive regulation of specific transcription from RNA polymerase II promoter;; positive regulation of transcription;; promoter binding;; protein binding;; protein dimerization activity;; protein homodimerization activity;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; RNA polymerase II transcription factor activity, enhancer binding;; sequence-specific DNA binding;; specific RNA polymerase II transcription factor activity;; transcription;; transcription factor activity;; transcription factor complex;; urea cycle cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; RNA polymerase II transcription factor activity;; transcription factor activity biological regulation;; cellular component organization;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell communication;; cell proliferation;; cellular developmental process;; cellular metabolic process;; developmental maturation;; embryonic development;; immune system development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 190.8741 195.6832 207.9852 458.7796 369.1894 408.2042 0.0029653493 -1.05128 7.62973 8.68101 1330199 1419024_at 1 B UGA Mm.374437 19243 Ptp4a1 Protein tyrosine phosphatase 4a1 (Ptp4a1), mRNA cell cycle;; cytoplasm;; dephosphorylation;; endoplasmic reticulum;; endosome;; hydrolase activity;; membrane;; multicellular organismal development;; phosphatase activity;; phosphoprotein phosphatase activity;; plasma membrane;; positive regulation of cell migration;; prenylated protein tyrosine phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process cell cycle;; cell motility;; cell motion;; cellular metabolic process;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion 50.2953 56.1507 54.8053 112.1468 109.7212 129.4230 0.00055010378 -1.12102 5.74661 6.86763 1330207 1419033_at X chrX:48245741-48246226 X A5 UGA Mm.46254 Transcribed locus, strongly similar to XP_001477930.1 PREDICTED: FERM domain containing 7 [Mus musculus] 63.7211 59.8912 64.4887 149.3739 189.7943 145.9489 0.0051116231 -1.35715 5.96965 7.32680 1343807 1419186_a_at 1 chr1:97484294-97484817 1 D chr1:97484258-97564171 1 D RSQ Mm.306228 NM_009183 1 1 20452 St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (St8sia4), transcript variant 1, mRNA. Steps in the Glycosylation of Mammalian N-linked Oligosaccarides alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;; Golgi apparatus;; integral to Golgi membrane;; integral to membrane;; membrane;; protein amino acid glycosylation;; sialyltransferase activity;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 128.3149 139.0049 161.2752 241.5994 299.3996 368.5408 0.011764295 -1.07072 7.15197 8.22269 1330770 1419742_at 2 chr2:130972272-130972647 2 F1 chr2:130972060-130985756 2 F1 RSQ Mm.27711 NM_026091 1 1 67326 RP23-32L15.2 1700037H04Rik RIKEN cDNA 1700037H04 gene (1700037H04Rik), mRNA. 145.6945 164.9446 162.3797 361.2231 461.2620 475.8007 0.0025828068 -1.44818 7.29862 8.74680 1344152 1420715_a_at 6 52.7 cM chr6:115439974-115440254 6 E3 chr6:115372083-115440419 6 E3 RSQ Mm.3020 NM_011146 2 1 19016 Pparg peroxisome proliferator activated receptor gamma (Pparg), transcript variant 2, mRNA. Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression;; Nuclear Receptors in Lipid Metabolism and Toxicity;; Role of PPAR-gamma Coactivators in Obesity and Thermogenesis;; Visceral Fat Deposits and the Metabolic Syndrome Huntington's disease;; Pathways in cancer;; PPAR signaling pathway;; Thyroid cancer CLASS Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Thyroid Cancer [PATH:mmu05216] Human Diseases; Neurodegenerative Diseases; Huntington's disease [PATH:mmu05016] arachidonic acid binding;; brown fat cell differentiation;; cell fate commitment;; chromatin binding;; cytosol;; DNA binding;; DNA binding;; epithelial cell differentiation;; fat cell differentiation;; fat cell differentiation;; inflammatory response;; ligand-dependent nuclear receptor activity;; long-chain fatty acid transport;; metal ion binding;; negative regulation of cell proliferation;; negative regulation of cytokine production;; negative regulation of transcription from RNA polymerase II promoter;; negative regulation of transcription, DNA-dependent;; nucleus;; placenta development;; positive regulation of fat cell differentiation;; positive regulation of fat cell differentiation;; positive regulation of transcription;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; receptor activity;; regulation of fat cell differentiation;; regulation of fat cell differentiation;; regulation of transcription;; regulation of transcription, DNA-dependent;; response to lipid;; sequence-specific DNA binding;; steroid hormone receptor activity;; transcription;; transcription activator activity;; transcription factor activity;; transcription repressor activity;; transcription repressor activity;; transcriptional repressor complex;; white fat cell differentiation;; white fat cell differentiation;; zinc ion binding cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; molecular transducer activity;; transcription regulator activity carboxylic acid binding;; chromatin binding;; ion binding;; lipid binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription activator activity;; transcription factor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; negative regulation of multicellular organismal process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of multicellular organismal process;; response to chemical stimulus;; response to external stimulus;; response to stress;; transport 133.1177 120.7424 117.1975 191.5096 252.4297 332.6812 0.039907141 -1.03129 6.94838 7.97967 1344266 1421149_a_at 6 60.21 cM chr6:124692719-124693272 6 F2 chr6:124692561-124706505 6 F2 RSQ Mm.333380 NM_007881 2 2 13498 Atn1 atrophin 1 (Atn1), mRNA. cytoplasm;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; nucleus;; protein binding;; toxin metabolic process;; toxin receptor binding;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; secondary metabolic process 43.9413 49.2716 55.1182 119.5417 124.2635 156.3065 0.00096338252 -1.42741 5.62155 7.04895 1331990 1421555_at 8 10.0 cM chr8:28337294-28338230 8 A2 chr8:28336247-28340060 8 A2 RSQ Mm.278475 NM_013462 1 1 11556 Adrb3 adrenergic receptor, beta 3 (Adrb3), mRNA. Calcium signaling pathway;; Endocytosis CLASS Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144];; Neuroactive ligand-receptor interaction activation of adenylate cyclase activity by G-protein signaling pathway;; adrenoceptor activity;; beta-3 adrenergic receptor binding;; beta-adrenergic receptor activity;; brown fat cell differentiation;; diet induced thermogenesis;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; heat generation;; integral to membrane;; membrane;; membrane fraction;; negative regulation of multicellular organism growth;; plasma membrane;; receptor activity;; response to cold;; signal transducer activity;; signal transduction;; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure cell;; cell part cell fraction;; cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell communication;; cellular developmental process;; cellular metabolic process;; multicellular organism growth;; multicellular organismal metabolic process;; negative regulation of biological process;; negative regulation of growth;; negative regulation of multicellular organismal process;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of molecular function;; regulation of multicellular organismal process;; response to abiotic stimulus;; response to dietary excess;; response to stress;; system process;; temperature homeostasis 62.6017 69.2477 64.4220 130.6714 199.6548 222.0753 0.02172261 -1.45825 6.03043 7.48869 1332082 1421681_at 9 chr9:55069139-55090023 9 B chr9:55068028-55131432 9 B RSQ Mm.443874 NM_032002 1 1 83961 Nrg4 neuregulin 4 (Nrg4), mRNA. g-Secretase mediated ErbB4 Signaling Pathway ErbB signaling pathway CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] extracellular region;; growth factor activity;; integral to membrane;; membrane;; plasma membrane cell;; cell part;; extracellular region cell part;; membrane;; membrane part binding protein binding 238.7650 240.0570 217.1702 504.0869 512.8958 551.5580 5.4384816e-05 -1.17269 7.85645 9.02914 1332679 1422508_at 16 chr16:44085965-44086095 16 B4 chr16:44085516-44139132 16 B4 RSQ Mm.217787 NM_007508 1 1 11964 Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), mRNA. Metabolic pathways CLASS Metabolism; Energy Metabolism; Oxidative phosphorylation [PATH:mmu00190];; Oxidative phosphorylation ATP binding;; ATP metabolic process;; ATP synthesis coupled proton transport;; cytosol;; hydrogen ion transmembrane transporter activity;; hydrogen ion transporting ATP synthase activity, rotational mechanism;; hydrolase activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; ion transport;; mitochondrion;; nucleotide binding;; plasma membrane;; proton transport;; proton-transporting ATPase activity, rotational mechanism;; proton-transporting two-sector ATPase complex;; proton-transporting two-sector ATPase complex, catalytic domain;; proton-transporting V-type ATPase, V1 domain;; transport cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; protein complex binding;; catalytic activity;; transporter activity hydrolase activity;; nucleoside binding;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; nitrogen compound metabolic process;; primary metabolic process;; transmembrane transport;; transport 1283.0679 1238.9763 1194.2830 2213.8986 2651.0081 2870.6519 0.0075397023 -1.04987 10.27408 11.32395 1344742 1422973_a_at 7 chr7:104565546-104565932 7 E1 chr7:104561466-104566020 7 E1 RSQ Mm.28585 NM_009381 1 1 21835 Thrsp thyroid hormone responsive SPOT14 homolog (Rattus) (Thrsp), mRNA. nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 444.5087 404.5952 412.7075 873.6589 720.5835 1082.9938 0.019607669 -1.06646 8.71513 9.78159 1333185 1423152_at 2 103.0 cM chr2:173604288-173604593 2 H4 chr2:173563071-173609837 2 H4 RSQ Mm.260456 NM_019806 1 1 56491 RP23-383L13.1 Vapb vesicle-associated membrane protein, associated protein B and C (Vapb), mRNA. integral to membrane;; membrane;; membrane fraction;; plasma membrane;; structural molecule activity cell;; cell part cell fraction;; cell part;; membrane;; membrane part structural molecule activity 491.7432 463.1621 482.0518 1215.1582 1098.1363 1109.8630 0.00013137363 -1.25125 8.90339 10.15465 1333463 1423488_at 11 chr11:90138754-90139257 11 C chr11:90110789-90139887 11 C RSQ Mm.277518 NM_026178 2 2 67468 RP23-220F20.1 Mmd monocyte to macrophage differentiation-associated (Mmd), mRNA. cytolysis;; endosome;; integral to membrane;; lysosome;; membrane;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle molecular transducer activity signal transducer activity cellular process;; death cell death 843.3732 796.3962 784.2800 1854.2693 1607.5960 1746.0964 0.00045441942 -1.10155 9.65753 10.75908 1333464 1423489_at 11 chr11:90139426-90139743 11 C chr11:90110789-90139887 11 C RSQ Mm.277518 NM_026178 2 2 67468 RP23-220F20.1 Mmd monocyte to macrophage differentiation-associated (Mmd), mRNA. cytolysis;; endosome;; integral to membrane;; lysosome;; membrane;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle molecular transducer activity signal transducer activity cellular process;; death cell death 434.6932 414.6661 400.0567 807.0964 820.1449 1059.4223 0.0092673261 -1.09389 8.70124 9.79513 1344891 1423706_a_at 4 77.6 cM chr4:148524331-148524689 4 E2 chr4:148524093-148540816 4 E2 RSQ Mm.252080 NM_001081274 1 1 110208 RP23-249G3.4 Pgd phosphogluconate dehydrogenase (Pgd), mRNA. Glutathione metabolism;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [PATH:mmu00030] Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism [PATH:mmu00480];; Pentose phosphate pathway binding;; catalytic activity;; coenzyme binding;; metabolic process;; NADP or NADPH binding;; oxidation reduction;; oxidoreductase activity;; pentose biosynthetic process;; pentose-phosphate shunt;; phosphogluconate 2-dehydrogenase activity;; phosphogluconate dehydrogenase (decarboxylating) activity binding;; catalytic activity cofactor binding;; nucleotide binding;; oxidoreductase activity cellular process;; metabolic process alcohol metabolic process;; biosynthetic process;; catabolic process;; cellular metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process;; secondary metabolic process 2416.3855 2357.6985 2369.9274 5288.7935 5716.0919 7418.1797 0.011395055 -1.35132 11.21748 12.56880 1333715 1423828_at 11 72.0 cM chr11:120668427-120668973 11 E2 chr11:120667271-120685861 11 E2 RSQ Mm.236443 NM_007988 1 1 14104 RP23-99M13.6 Fasn fatty acid synthase (Fasn), mRNA. Fatty acid biosynthesis;; Insulin signaling pathway CLASS Metabolism; Lipid Metabolism; Fatty acid biosynthesis [PATH:mmu00061] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910];; Metabolic pathways 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity;; 3-oxoacyl-[acyl-carrier-protein] reductase activity;; 3-oxoacyl-[acyl-carrier-protein] synthase activity;; [acyl-carrier-protein] S-acetyltransferase activity;; [acyl-carrier-protein] S-malonyltransferase activity;; acyl carrier activity;; acyltransferase activity;; binding;; biosynthetic process;; catalytic activity;; cofactor binding;; cytoplasm;; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity;; fatty acid biosynthetic process;; fatty-acid synthase activity;; glycogen granule;; hydrolase activity;; hydrolase activity, acting on ester bonds;; lipid biosynthetic process;; lyase activity;; metabolic process;; oleoyl-[acyl-carrier-protein] hydrolase activity;; oxidation reduction;; oxidoreductase activity;; phosphopantetheine binding;; transferase activity;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity;; transporter activity amine binding;; carboxylic acid binding;; cofactor binding;; hydrolase activity;; ion binding;; lyase activity;; oxidoreductase activity;; substrate-specific transporter activity;; transferase activity;; vitamin binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; oxidation reduction;; primary metabolic process 302.4900 263.0497 290.3726 612.7475 607.2283 535.0130 0.00029017291 -1.03566 8.15390 9.18956 1333913 1424086_at 9 23.0 cM chr9:43030228-43030494 9 A5.1 chr9:43029360-43047899 9 A5.1 RSQ Mm.246479 NM_178644 1 1 102644 Oaf OAF homolog (Drosophila) (Oaf), mRNA. 579.7830 553.0904 530.0941 1348.9521 1126.1295 1110.0311 0.0025442389 -1.10344 9.11362 10.21705 1334125 1424357_at 9 chr9:31233861-31234366 9 A4 chr9:31233780-31271823 9 A4 RSQ Mm.390134 NM_144936 1 1 235135 Tmem45b transmembrane protein 45b (Tmem45b), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 45.2415 46.0675 51.6878 97.0399 109.8771 138.2075 0.0068574794 -1.25798 5.57233 6.83031 1334291 1424567_at 3 chr3:102574564-102574656 3 F2.2 chr3:102538692-102576215 3 F2.2 RSQ Mm.477505 NM_027533 1 1 70747 Tspan2 tetraspanin 2 (Tspan2), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 353.2630 356.2427 388.5157 916.5180 626.8934 740.6832 0.016792167 -1.04055 8.51438 9.55494 1345191 1424948_x_at 17 B1|17 18.44 cM chr17:34133284-34134088 17 B1 UG5 Mm.422886 14972 H2-K1 Histocompatibility 2, K1, K region, mRNA (cDNA clone MGC:7052 IMAGE:3156482) Allograft rejection;; Antigen processing and presentation;; Autoimmune thyroid disease;; Cell adhesion molecules (CAMs);; Endocytosis;; Graft-versus-host disease CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] Cellular Processes; Immune System;;; Natural killer cell mediated cytotoxicity;; Type I diabetes mellitus antigen processing and presentation;; antigen processing and presentation of exogenous peptide antigen via MHC class I;; antigen processing and presentation of peptide antigen via MHC class I;; defense response to bacterium;; external side of plasma membrane;; immune response;; integral to membrane;; membrane;; MHC class I protein complex;; peptide antigen binding;; positive regulation of T cell mediated cytotoxicity cell;; cell part;; macromolecular complex cell part;; cell surface;; membrane;; membrane part;; protein complex binding antigen binding;; peptide binding biological regulation;; cell killing;; cellular process;; death;; developmental process;; immune system process;; multi-organism process;; positive regulation of biological process;; regulation of biological process;; response to stimulus antigen processing and presentation;; cell death;; immune effector process;; immune response;; leukocyte mediated cytotoxicity;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; positive regulation of response to stimulus;; regulation of biological process;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of response to stimulus;; response to biotic stimulus;; response to other organism;; response to stress 86.5724 113.9313 95.1100 182.9297 193.0831 218.4320 0.0032909694 -1.01329 6.61313 7.62642 1334756 1425216_at 7 chr7:31603441-31603954 7 B1 chr7:31603375-31608794 7 B1 RSQ Mm.97338 NM_146187 1 1 233079 Ffar2 free fatty acid receptor 2 (Ffar2), mRNA. G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; lipid binding;; membrane;; plasma membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity lipid binding;; signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 425.1647 387.1497 374.6671 1180.6126 1000.0470 1757.5787 0.016002772 -1.69082 8.62603 10.31685 1334817 1425326_at 11 chr11:100338538-100342819 11 D chr11:100337669-100389215 11 D RSQ Mm.282039 NM_134037 1 1 104112 RP23-392I3.9 Acly ATP citrate lyase (Acly), mRNA. Shuttle for transfer of acetyl groups from mitochondria to the cytosol Citrate cycle (TCA cycle);; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Citrate cycle (TCA cycle) [PATH:mmu00020] Metabolism; Energy Metabolism; Reductive carboxylate cycle (CO2 fixation) [PATH:mmu00720];; Reductive carboxylate cycle (CO2 fixation) acetyl-CoA biosynthetic process;; ATP binding;; ATP citrate synthase activity;; binding;; catalytic activity;; cellular carbohydrate metabolic process;; cytoplasm;; intracellular;; lipid biosynthetic process;; lyase activity;; magnesium ion binding;; metabolic process;; metal ion binding;; nucleotide binding;; protein binding;; succinate-CoA ligase (ADP-forming) activity;; transferase activity;; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; ligase activity;; lyase activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 62.8204 65.2644 55.5615 187.8805 189.8574 131.0361 0.0072815974 -1.45296 5.93247 7.38542 1345371 1425436_x_at 6 62.69 cM chr6:130128783-130128874 6 F3 chr6:130128699-130143130 6 F3 RSQ Mm.457996 NM_010651 2 2 16640 Klra9 killer cell lectin-like receptor subfamily A, member 9 (Klra9), mRNA. Graft-versus-host disease CLASS Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] Human Diseases; Immune Disorders; Graft-versus-host disease [PATH:mmu05332];; Natural killer cell mediated cytotoxicity plasma membrane;; receptor activity;; sugar binding cell;; cell part cell part;; membrane binding;; molecular transducer activity carbohydrate binding;; signal transducer activity 123.8346 107.5586 104.3988 241.5908 228.4367 251.2003 0.00097306656 -1.10585 6.80240 7.90826 1345392 1425477_x_at 17 B1|17 18.64 cM UG5 Mm.254067 14961 H2-Ab1 Histocompatibility 2, class II antigen A, beta 1, mRNA (cDNA clone MGC:6297 IMAGE:2651058) Allograft rejection;; Antigen processing and presentation;; Asthma;; Autoimmune thyroid disease;; Cell adhesion molecules (CAMs);; Graft-versus-host disease CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Immune System; Antigen processing and presentation [PATH:mmu04612] Human Diseases; Immune Disorders; Asthma [PATH:mmu05310] Human Diseases; Immune Disorders; Systemic lupus erythema;; Systemic lupus erythematosus;; Type I diabetes mellitus antigen processing and presentation;; antigen processing and presentation of exogenous peptide antigen via MHC class II;; antigen processing and presentation of peptide antigen;; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;; early endosome;; external side of plasma membrane;; Golgi apparatus;; immune response;; integral to membrane;; intracellular;; membrane;; MHC class II protein complex;; multivesicular body;; peptide antigen binding;; plasma membrane;; protein binding cell;; cell part;; macromolecular complex;; organelle cell part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; protein complex binding antigen binding;; peptide binding;; protein binding immune system process;; response to stimulus antigen processing and presentation;; immune response 831.1004 771.4788 776.3932 1441.7902 1547.4986 1889.1281 0.0083341282 -1.02729 9.63034 10.65762 1345403 1425519_a_at 18 32.0 cM chr18:60963502-60972306 18 E1 RSQ Mm.439737 NM_010545 2 1 16149 Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), transcript variant 2, mRNA. Antigen processing and presentation CLASS Cellular Processes; Immune System; Antigen processing and presentation [PATH:mmu04612] antigen processing and presentation;; antigen processing and presentation;; antigen processing and presentation of exogenous peptide antigen via MHC class II;; chaperone mediated protein folding requiring cofactor;; chaperone mediated protein folding requiring cofactor;; defense response;; endoplasmic reticulum;; external side of plasma membrane;; Golgi apparatus;; immune response;; immunoglobulin mediated immune response;; integral to membrane;; integral to plasma membrane;; intracellular protein transport;; intracellular protein transport;; late endosome;; lysosome;; membrane;; MHC class II protein binding;; multivesicular body;; negative regulation of T cell differentiation;; negative thymic T cell selection;; plasma membrane;; plasma membrane;; positive regulation of T cell differentiation;; positive thymic T cell selection;; protein binding;; protein complex assembly cell;; cell part;; organelle cell part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding protein binding anatomical structure formation;; biological regulation;; cellular component biogenesis;; cellular component organization;; cellular process;; developmental process;; establishment of localization;; immune system process;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; antigen processing and presentation;; cell activation;; cellular component assembly;; cellular developmental process;; cellular localization;; cellular metabolic process;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; immune effector process;; immune response;; immune system development;; leukocyte activation;; macromolecular complex subunit organization;; macromolecule localization;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of immune system process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; primary metabolic process;; protein complex biogenesis;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of multicellular organismal process;; response to stress;; T cell selection;; transport 91.2814 86.8904 85.8613 194.3674 160.2018 216.4238 0.010393606 -1.10226 6.45910 7.56137 1345423 1425559_a_at 7 chr7:126924372-126927888 7 F2 chr7:126904436-126928407 7 F2 RSQ Mm.334199 NM_212442 3 1 20216 Acsm3 acyl-CoA synthetase medium-chain family member 3 (Acsm3), transcript variant 3, mRNA. Butanoate metabolism;; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Butanoate metabolism [PATH:mmu00650] ATP binding;; butyrate-CoA ligase activity;; catalytic activity;; fatty acid biosynthetic process;; fatty acid metabolic process;; fatty-acid ligase activity;; ligase activity;; lipid metabolic process;; magnesium ion binding;; metabolic process;; metal ion binding;; mitochondrial matrix;; mitochondrion;; nucleotide binding cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding;; catalytic activity ion binding;; ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 45.0858 42.1229 43.3421 96.5529 83.6218 87.4996 0.00083713221 -1.03381 5.44294 6.47675 1334972 1425596_at 10 B1 chr10:39722016-39722362 10 B1 UGA Mm.55513 215929 AI317395 Expressed sequence AI317395 (AI317395), mRNA carbohydrate transport;; integral to membrane;; ion transport;; membrane;; plasma membrane;; sodium ion binding;; sodium ion transport;; sugar:hydrogen symporter activity;; symporter activity;; transport cell;; cell part cell part;; membrane;; membrane part binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 105.8898 111.8599 130.1395 279.6696 248.2999 360.8186 0.0044352497 -1.34092 6.85196 8.19288 1345622 1425967_a_at 14 20.0 cM chr14:56679515-56680545 14 C3 chr14:56678580-56681147 14 C3 RSQ Mm.439684 NM_010779 1 1 17227 Mcpt4 mast cell protease 4 (Mcpt4), mRNA. hydrolase activity;; intracellular;; peptidase activity;; proteolysis;; serine-type endopeptidase activity;; serine-type peptidase activity cell;; cell part cell part;; intracellular catalytic activity hydrolase activity metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process 30.2736 23.3141 24.0641 54.8253 86.5457 82.5615 0.0069344917 -1.50921 4.68398 6.19319 1335414 1426433_at 10 chr10:4739751-4752813 10 A1 RSQ Mm.338242 NM_026793 1 1 68632 Myct1 myc target 1 (Myct1), mRNA. integral to membrane;; membrane;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle 726.4197 716.0649 686.5129 1384.7015 1458.9940 1471.5683 1.1290479e-05 -1.01917 9.47058 10.48975 1335439 1426464_at 11 chr11:98629636-98631067 11 D chr11:98629248-98636556 11 D RSQ Mm.390397 NM_145434 1 1 217166 RP23-395E10.7 Nr1d1 nuclear receptor subfamily 1, group D, member 1 (Nr1d1), mRNA. Circadian rhythm - mammal CLASS Cellular Processes; Behavior; Circadian rhythm - mammal [PATH:mmu04710] circadian rhythm;; DNA binding;; ligand-dependent nuclear receptor activity;; metal ion binding;; nucleus;; receptor activity;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; steroid hormone receptor activity;; transcription;; transcription factor activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; signal transducer activity;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process;; rhythmic process biosynthetic process;; cellular metabolic process;; circadian rhythm;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 388.6323 404.7875 385.6577 706.6519 904.8291 902.4952 0.0098337064 -1.08322 8.61815 9.70138 1335537 1426607_at 13 chr13:120276845-120284312 13 D2.3 RSQ Mm.46679 NM_001039244 1 1 633640 Gm7120 predicted gene 7120 (Gm7120), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 45.0397 35.6668 37.3841 89.9039 94.0006 65.0130 0.0094807321 -1.06452 5.29133 6.35586 1335789 1426952_at 10 chr10:26637764-26638019 10 A4 chr10:26492317-26638454 10 A4 RSQ Mm.356496 NM_176837 1 1 73910 Arhgap18 Rho GTPase activating protein 18 (Arhgap18), mRNA. GTPase activator activity;; intracellular;; signal transduction cell;; cell part cell part;; intracellular enzyme regulator activity enzyme activator activity;; nucleoside-triphosphatase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 33.3882 27.1549 37.2293 88.1138 73.8195 84.3237 0.0024981736 -1.34077 5.01426 6.35503 1336073 1427301_at 1 93.3 cM chr1:173629579-173629781 1 H3 chr1:173612185-173635388 1 H3 RSQ Mm.1738 NM_007649 1 1 12506 Cd48 CD48 antigen (Cd48), mRNA. Natural killer cell mediated cytotoxicity CLASS Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] anchored to membrane;; eukaryotic cell surface binding;; external side of plasma membrane;; membrane;; plasma membrane;; protein binding;; response to protein stimulus;; signal transduction;; T cell activation cell;; cell part cell part;; cell surface;; membrane;; membrane part binding cell surface binding;; protein binding biological regulation;; cellular process;; immune system process;; regulation of biological process;; response to stimulus cell activation;; cell communication;; leukocyte activation;; regulation of biological process;; regulation of cellular process;; response to chemical stimulus 82.3272 86.3048 97.0230 555.4214 205.7242 292.5824 0.043595931 -1.86659 6.46497 8.33157 1336105 1427343_at 8 C1 chr8:77747442-77747638 8 C1 UG5 Mm.179267 75141 Rasd2 RASD family, member 2, mRNA (cDNA clone IMAGE:4988981) GTP binding;; intracellular;; locomotory behavior;; membrane;; nucleotide binding;; small GTPase mediated signal transduction cell;; cell part cell part;; intracellular;; membrane binding nucleotide binding biological regulation;; cellular process;; regulation of biological process;; response to stimulus behavior;; cell communication;; regulation of biological process;; regulation of cellular process 27.5186 19.7115 20.5339 72.4086 48.3279 40.2444 0.020892518 -1.22012 4.48108 5.70120 1336159 1427426_at 1 A5 chr1:21391726-21392265 1 A4 UGA Mm.336519 226922 Kcnq5 Voltage-gated potassium channel KCNQ5 (Kcnq5) integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 59.4201 60.2677 63.4561 108.7576 116.4071 146.1604 0.012721137 -1.00851 5.93129 6.93981 1346139 1427580_a_at 12 F1|12 54.5 cM chr12:110889243-110890147 12 F1 UGA Mm.293263 75745 Rian MRNA, MBII-343 snoRNA nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 19.0506 19.4800 17.8298 61.5157 58.4955 78.0293 0.0027802828 -1.80239 4.23064 6.03303 1336527 1428005_at 1 chr1:186611301-186611707 1 H5 chr1:186610645-186635192 1 H5 RSQ Mm.272457 NM_001081361 3 2 66112 Mosc1 MOCO sulphurase C-terminal domain containing 1 (Mosc1), mRNA. catalytic activity;; mitochondrial inner membrane;; mitochondrion;; molybdenum ion binding;; oxidation reduction;; oxidoreductase activity;; pyridoxal phosphate binding cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; catalytic activity cofactor binding;; ion binding;; lipid binding;; oxidoreductase activity;; vitamin binding metabolic process oxidation reduction 173.2343 166.9675 179.0341 339.5461 350.6263 385.0895 0.00040067965 -1.04874 7.43470 8.48343 1336703 1428333_at X chrX:132529324-132529820 X F1 chrX:132528369-132529894 X F1 RSQ NR_003642 1 1 76976 2900062L11Rik RIKEN cDNA 2900062L11 gene (2900062L11Rik), non-coding RNA. 233.3687 203.4130 212.4986 519.5960 494.7121 413.1456 0.0017181017 -1.13205 7.75535 8.88740 1346671 1431469_a_at 18 chr18:36018867-36020465 18 B2 chr18:35989471-36021342 18 B2 RSQ Mm.94560 NM_133687 1 1 67393 Cxxc5 CXXC finger 5 (Cxxc5), mRNA. cytoplasm;; DNA binding;; metal ion binding;; nucleus;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding 888.8382 813.7706 841.9954 2348.5575 2883.4864 2884.6519 0.0012940561 -1.66781 9.72731 11.39511 1337510 1434340_at 11 A1 UGA Mm.269736 66152 RP23-280J3.4 1110020P15Rik RIKEN cDNA 1110020P15 gene, mRNA (cDNA clone MGC:37480 IMAGE:4984172) Alzheimer's disease;; Cardiac muscle contraction;; Huntington's disease CLASS Metabolism; Energy Metabolism; Oxidative phosphorylation [PATH:mmu00190] Cellular Processes; Circulatory System; Cardiac muscle contraction [PATH:mmu04260] Human Diseases; Neurodegenerative Diseases; Alzheimer's disease [PATH:mmu05010] Human Diseases; Neurodegenerative Diseases; Parkinson's disease [PATH:mmu05012] Human Diseas;; Metabolic pathways;; Oxidative phosphorylation;; Parkinson's disease electron transport chain;; membrane;; mitochondrial electron transport, ubiquinol to cytochrome c;; mitochondrial envelope;; mitochondrial inner membrane;; mitochondrion;; respiratory chain;; transport;; ubiquinol-cytochrome-c reductase activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part catalytic activity;; transporter activity oxidoreductase activity;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; oxidation reduction;; transport 1146.2013 1059.3887 1048.0854 2212.6519 2347.4852 2083.9050 0.00011356004 -1.02944 10.08173 11.11118 1347039 1434341_x_at 11 A1 chr11:4602128-4604281 11 A1 UGA Mm.269736 66152 RP23-280J3.4 1110020P15Rik RIKEN cDNA 1110020P15 gene, mRNA (cDNA clone MGC:37480 IMAGE:4984172) Alzheimer's disease;; Cardiac muscle contraction;; Huntington's disease CLASS Metabolism; Energy Metabolism; Oxidative phosphorylation [PATH:mmu00190] Cellular Processes; Circulatory System; Cardiac muscle contraction [PATH:mmu04260] Human Diseases; Neurodegenerative Diseases; Alzheimer's disease [PATH:mmu05010] Human Diseases; Neurodegenerative Diseases; Parkinson's disease [PATH:mmu05012] Human Diseas;; Metabolic pathways;; Oxidative phosphorylation;; Parkinson's disease electron transport chain;; membrane;; mitochondrial electron transport, ubiquinol to cytochrome c;; mitochondrial envelope;; mitochondrial inner membrane;; mitochondrion;; respiratory chain;; transport;; ubiquinol-cytochrome-c reductase activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part catalytic activity;; transporter activity oxidoreductase activity;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; oxidation reduction;; transport 109.9901 124.5968 152.9095 252.9448 249.8993 275.7422 0.011764243 -1.01872 6.99963 8.01835 1347882 1438634_x_at 11 56.0 cM chr11:97699966-97700055 11 D chr11:97660985-97700078 11 D RSQ Mm.271967 NM_010688 1 1 16796 RP23-386E10.6 Lasp1 LIM and SH3 protein 1 (Lasp1), mRNA. actin binding;; actin filament binding;; cytoplasm;; cytoskeleton;; focal adhesion;; ion transport;; metal ion binding;; protein binding;; transport;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle binding ion binding;; protein binding establishment of localization;; localization establishment of localization;; transport 210.4487 201.0995 235.8607 616.4443 845.5585 685.2976 0.0014878131 -1.72043 7.75029 9.47072 1347891 1438651_a_at 2 chr2:84979971-84980073 2 D chr2:84976516-84980080 2 D RSQ Mm.29368 NM_011784 1 1 23796 RP23-366I14.3 Aplnr apelin receptor (Aplnr), mRNA. Neuroactive ligand-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; plasma membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 2311.3927 2247.3099 2254.7075 5004.1541 5097.7609 6287.6519 0.006354349 -1.25854 11.14908 12.40762 1348090 1439443_x_at 14 chr14:31386607-31386776 14 B chr14:31362334-31387908 14 B RSQ Mm.290692 NM_009388 1 1 21881 Tkt transketolase (Tkt), mRNA. Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [PATH:mmu00030] Metabolism; Biosynthesis of Polyketides and Nonribosomal Peptides; Biosynthesis of ansamycins;; Pentose phosphate pathway calcium ion binding;; catalytic activity;; metabolic process;; metal ion binding;; regulation of growth;; transferase activity;; transketolase activity binding;; catalytic activity ion binding;; transferase activity biological regulation;; growth;; metabolic process;; regulation of biological process regulation of biological process;; regulation of growth 752.3772 798.7728 797.7909 1704.9347 1367.9235 2415.7804 0.036689836 -1.18491 9.61227 10.79718 1348104 1439459_x_at 11 chr11:100337689-100337814 11 D chr11:100337669-100389215 11 D RSQ Mm.282039 NM_134037 1 1 104112 RP23-392I3.9 Acly ATP citrate lyase (Acly), mRNA. Shuttle for transfer of acetyl groups from mitochondria to the cytosol Citrate cycle (TCA cycle);; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Citrate cycle (TCA cycle) [PATH:mmu00020] Metabolism; Energy Metabolism; Reductive carboxylate cycle (CO2 fixation) [PATH:mmu00720];; Reductive carboxylate cycle (CO2 fixation) acetyl-CoA biosynthetic process;; ATP binding;; ATP citrate synthase activity;; binding;; catalytic activity;; cellular carbohydrate metabolic process;; cytoplasm;; intracellular;; lipid biosynthetic process;; lyase activity;; magnesium ion binding;; metabolic process;; metal ion binding;; nucleotide binding;; protein binding;; succinate-CoA ligase (ADP-forming) activity;; transferase activity;; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; ligase activity;; lyase activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 125.2912 125.7983 110.5522 364.1519 246.6005 358.7981 0.010551215 -1.40292 6.91090 8.31382 1338760 1448201_at 3 38.5 cM chr3:83577660-83577987 3 E3 chr3:83570242-83578236 3 E3 RSQ Mm.19155 NM_009144 1 1 20319 Sfrp2 secreted frizzled-related protein 2 (Sfrp2), mRNA. Wnt signaling pathway CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] anterior/posterior pattern formation;; cell differentiation;; cellular response to extracellular stimulus;; extracellular region;; multicellular organismal development;; somitogenesis;; Wnt receptor signaling pathway extracellular region biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process;; response to stimulus cell communication;; cellular developmental process;; cellular response to stimulus;; embryonic development;; multicellular organismal development;; pattern specification process;; regulation of biological process;; regulation of cellular process;; response to external stimulus 198.9852 174.2487 180.8634 425.2079 343.8897 423.5509 0.002014924 -1.10131 7.52676 8.62807 1338998 1448507_at 1 chr1:89206841-89207235 1 D chr1:89160938-89207366 1 D RSQ Mm.247951 NM_028889 1 1 98363 Efhd1 EF hand domain containing 1 (Efhd1), mRNA. calcium ion binding;; mitochondrial inner membrane;; neuron projection development cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding ion binding cellular component organization;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; cell projection organization;; cellular developmental process;; multicellular organismal development 41.1549 37.0941 38.7050 87.9308 108.7108 137.4182 0.011811138 -1.49151 5.28352 6.77503 1339165 1448710_at 1 67.4 cM chr1:130485067-130485335 1 E4 chr1:130484775-130488876 1 E4 RSQ Mm.1401 NM_009911 1 1 12767 Cxcr4 chemokine (C-X-C motif) receptor 4 (Cxcr4), mRNA. CXCR4 Signaling Pathway;; Pertussis toxin-insensitive CCR5 Signaling in Macrophage;; Selective expression of chemokine receptors during T-cell polarization Axon guidance;; Chemokine signaling pathway;; Cytokine-cytokine receptor interaction;; Endocytosis;; Leukocyte transendothelial migration CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu04060] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670] Cellular Processes; ameboidal cell migration;; brain development;; C-C chemokine receptor activity;; C-X-C chemokine receptor activity;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; germ cell development;; germ cell migration;; growth cone;; integral to membrane;; membrane;; motor axon guidance;; nervous system development;; neuron migration;; organ morphogenesis;; patterning of blood vessels;; plasma membrane;; receptor activity;; regulation of cell migration;; regulation of cell migration;; signal transducer activity;; signal transduction;; T cell proliferation cell;; cell part cell part;; cell projection;; membrane;; membrane part;; site of polarized growth binding;; molecular transducer activity peptide binding;; protein binding;; signal transducer activity anatomical structure formation;; biological regulation;; cellular component organization;; cellular process;; developmental process;; immune system process;; localization;; locomotion;; multicellular organismal process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell activation;; cell communication;; cell motility;; cell motion;; cell projection organization;; cell proliferation;; cellular component morphogenesis;; cellular developmental process;; gamete generation;; leukocyte activation;; localization of cell;; multicellular organismal development;; pattern specification process;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion;; reproductive process;; sexual reproduction 1110.5736 1127.1830 1101.2584 2421.6436 2282.7075 2597.6344 0.0017236298 -1.12692 10.12018 11.24709 1339273 1448842_at 18 23.0 cM chr18:46873195-46875358 18 C chr18:46872858-46887996 18 C RSQ Mm.241056 NM_033037 1 1 12583 Cdo1 cysteine dioxygenase 1, cytosolic (Cdo1), mRNA. Cysteine and methionine metabolism;; Cysteine metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Cysteine and methionine metabolism [PATH:mmu00270] Metabolism; Amino Acid Metabolism; Cysteine metabolism [PATH:mmu00272] Metabolism; Metabolism of Other Amino Acids; Taurine and hypotaurine metabolism [PATH:mmu00430];; Taurine and hypotaurine metabolism cysteine dioxygenase activity;; cytosol;; iron ion binding;; L-cysteine catabolic process to taurine;; L-cysteine metabolic process;; metal ion binding;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; taurine metabolic process cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; oxidoreductase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 68.7690 80.2497 68.5947 151.8920 156.7557 174.0615 0.00036202459 -1.15086 6.17671 7.32758 1339320 1448901_at 2 chr2:130217001-130218931 2 F1 chr2:130216510-130223365 2 F1 RSQ Mm.112701 NM_019696 1 1 56264 RP23-29K12.2 Cpxm1 carboxypeptidase X 1 (M14 family) (Cpxm1), mRNA. carboxypeptidase activity;; cell adhesion;; extracellular region;; extracellular space;; hydrolase activity;; metal ion binding;; metallocarboxypeptidase activity;; metallopeptidase activity;; peptidase activity;; proteolysis;; zinc ion binding extracellular region;; extracellular region part extracellular region part;; extracellular space binding;; catalytic activity hydrolase activity;; ion binding biological adhesion;; cellular process;; metabolic process catabolic process;; cell adhesion;; macromolecule metabolic process;; primary metabolic process 1398.3183 1424.3730 1359.0964 2605.0688 3613.9115 4098.4646 0.021562107 -1.27777 10.44467 11.72244 1339421 1449015_at 16 B5|16 32.6 cM chr16:48842672-48844529 16 B5 UGA Mm.441868 57262 Retnla Resistin like alpha, mRNA (cDNA clone MGC:35890 IMAGE:4189285) extracellular region;; hormone activity extracellular region binding protein binding 441.7566 405.5964 364.7840 664.5258 885.3742 1041.5601 0.017757859 -1.07632 8.65397 9.73029 1339514 1449135_at 2 96.0 cM chr2:181404769-181405114 2 H4 chr2:181404541-181406345 2 H4 RSQ Mm.264904 NM_009236 1 1 20672 Sox18 SRY-box containing gene 18 (Sox18), mRNA. angiogenesis;; DNA binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; vasculogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 178.8339 177.2192 177.4457 369.8286 370.8415 350.7776 0.00048840277 -1.03223 7.47437 8.50659 1339524 1449147_at 2 chr2:92454920-92455309 2 E1 chr2:92439863-92455409 2 E1 RSQ Mm.38021 NM_023850 1 1 76969 RP23-165L23.5 Chst1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (Chst1), mRNA. Keratan sulfate biosynthesis;; Metabolic pathways CLASS Metabolism; Glycan Biosynthesis and Metabolism; Keratan sulfate biosynthesis [PATH:mmu00533] carbohydrate metabolic process;; Golgi apparatus;; Golgi membrane;; inflammatory response;; integral to membrane;; keratan sulfotransferase activity;; membrane;; sulfotransferase activity;; transferase activity cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part catalytic activity transferase activity metabolic process;; response to stimulus primary metabolic process;; response to external stimulus;; response to stress 105.0715 98.6059 100.4643 243.4689 263.4501 262.9191 1.9084413e-05 -1.33936 6.66312 8.00248 1339578 1449211_at 1 chr1:187181209-187181563 1 H5 chr1:187156037-187181648 1 H5 RSQ Mm.227549 NM_011794 1 1 23827 Bpnt1 bisphosphate 3'-nucleotidase 1 (Bpnt1), mRNA. Sulfur metabolism CLASS Metabolism; Energy Metabolism; Sulfur metabolism [PATH:mmu00920] 3'(2'),5'-bisphosphate nucleotidase activity;; hydrolase activity;; inositol or phosphatidylinositol phosphatase activity;; lithium ion binding;; magnesium ion binding;; metal ion binding binding;; catalytic activity hydrolase activity;; ion binding 73.5858 72.4736 73.4358 143.3363 174.3599 156.7431 0.0051432031 -1.10743 6.19305 7.30048 1339828 1449514_at 19 55.0 cM chr19:61166433-61168180 19 D3 chr19:60965651-61168459 19 D3 RSQ Mm.279400 NM_018869 1 1 14773 Grk5 G protein-coupled receptor kinase 5 (Grk5), mRNA. Chemokine signaling pathway;; Endocytosis CLASS Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] ATP binding;; G-protein coupled receptor kinase activity;; kinase activity;; nucleotide binding;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; signal transducer activity;; signal transduction;; transferase activity binding;; catalytic activity;; molecular transducer activity nucleoside binding;; nucleotide binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 35.5649 51.1640 42.8819 87.9043 111.6607 95.4965 0.0044434268 -1.19549 5.41725 6.61274 1339853 1449545_at 11 chr11:33017469-33017991 11 A4 chr11:33017429-33047400 11 A4 RSQ Mm.339812 NM_008005 1 1 14172 RP23-413O19.3 Fgf18 fibroblast growth factor 18 (Fgf18), mRNA. MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Motility; Regulation of actin cytoskeleton [PATH:mmu04810] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Melanoma [PATH:mmu05218];; Pathways in cancer;; Regulation of actin cytoskeleton angiogenesis;; chondrocyte development;; endochondral ossification;; extracellular region;; fibroblast growth factor receptor binding;; growth factor activity;; intramembranous ossification;; lung development;; ossification;; positive regulation of cell proliferation;; positive regulation of vascular endothelial growth factor receptor signaling pathway;; signal transduction extracellular region binding protein binding anatomical structure formation;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; cell communication;; cell proliferation;; cellular developmental process;; multicellular organismal development;; ossification;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process 59.9717 58.7340 64.1202 146.6837 133.7965 128.3416 0.00017685077 -1.15976 5.92835 7.08810 1340027 1449839_at 8 B1.1|8 26.0 cM chr8:47724466-47724986 8 B1.1 UGA Mm.34405 12367 Casp3 Caspase 3, mRNA (cDNA clone MGC:46907 IMAGE:4482368) Apoptotic DNA fragmentation and tissue homeostasis;; Apoptotic Signaling in Response to DNA Damage;; B Cell Survival Pathway;; Caspase Cascade in Apoptosis;; D4-GDI Signaling Pathway;; FAS signaling pathway ( CD95 );; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Role of Mitochondria in Apoptotic Signaling;; Stress Induction of HSP Regulation;; TNFR1 Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Alzheimer's disease;; Amyotrophic lateral sclerosis (ALS);; Apoptosis;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Cell Growth and Death; p53 signaling pathway [PATH:mmu04115] Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:;; Huntington's disease;; MAPK signaling pathway;; Natural killer cell mediated cytotoxicity;; p53 signaling pathway;; Parkinson's disease;; Pathways in cancer apoptosis;; apoptosis;; apoptosis;; B cell homeostasis;; cell fate commitment;; cyclin-dependent protein kinase inhibitor activity;; cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; cytoplasm;; DNA fragmentation involved in apoptosis;; heart development;; hydrolase activity;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis by oxidative stress;; induction of apoptosis via death domain receptors;; keratinocyte differentiation;; negative regulation of activated T cell proliferation;; negative regulation of apoptosis;; negative regulation of B cell proliferation;; negative regulation of cell cycle;; negative regulation of cyclin-dependent protein kinase activity;; neuron apoptosis;; peptidase activity;; peptidase activity;; peptidase activity;; peptidase activity;; proteolysis;; release of cytochrome c from mitochondria;; response to DNA damage stimulus;; response to UV;; response to UV;; response to wounding;; sensory perception of sound;; T cell homeostasis cell;; cell part cell part;; intracellular;; intracellular part catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; hydrolase activity;; kinase regulator activity biological regulation;; cellular component organization;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell activation;; cell cycle;; cell death;; cell proliferation;; cellular component disassembly;; cellular developmental process;; cellular metabolic process;; leukocyte activation;; leukocyte homeostasis;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of immune system process;; nitrogen compound metabolic process;; organelle organization;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to external stimulus;; response to stress;; system process 89.0266 85.9540 84.4725 168.7150 199.3186 213.6166 0.0056205618 -1.15806 6.43402 7.59209 1340086 1449918_at 8 chr8:4136365-4137667 8 A1.1 chr8:4134245-4137707 8 A1.1 RSQ Mm.390006 XM_284376 2 1 70192 Cd209g PREDICTED: CD209g antigen (Cd209g), mRNA. integral to membrane;; membrane;; sugar binding cell;; cell part cell part;; membrane;; membrane part binding carbohydrate binding 167.7622 180.9728 191.8741 414.8807 401.2452 324.6121 0.0034468784 -1.07118 7.49131 8.56249 1340171 1450044_at 1 30.1 cM chr1:59543258-59543780 1 C1.3 chr1:59538990-59543799 1 C1.3 RSQ Mm.297906 NM_008057 1 1 14369 Fzd7 frizzled homolog 7 (Drosophila) (Fzd7), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signaling pathway [PATH:mmu04310] Cellular Processes; Endocrine System; Melanogenesis [PATH:mmu04916] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210] Human Diseases; Cancers; Basal cell carcinom;; Colorectal cancer;; Melanogenesis;; Pathways in cancer;; Wnt signaling pathway cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; receptor activity;; signal transducer activity;; signal transduction;; transmembrane receptor activity;; Wnt receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 18.6625 20.5990 19.4384 51.5856 40.7220 43.1129 0.0029695897 -1.19976 4.28914 5.48889 1340189 1450065_at 8 40.0 cM chr8:90853286-90853457 8 C3 chr8:90806890-90853861 8 C3 RSQ Mm.288206 NM_001109756 4 1 11513 Adcy7 adenylate cyclase 7 (Adcy7), transcript variant 4, mRNA. Calcium signaling pathway;; Chemokine signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Cellular Processes; Cell Communication; Gap junction [PATH:mmu04540] Cellular Processes; Circulatory System; Vascular smooth muscle contraction [PATH:mmu04270] Cellu;; Purine metabolism;; Vascular smooth muscle contraction activation of adenylate cyclase activity;; adenylate cyclase activity;; ATP binding;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; nucleotide binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity;; nucleoside binding;; nucleotide binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 116.9665 117.9322 117.8219 247.1964 253.1895 284.3426 0.0028395642 -1.15095 6.87741 8.02836 1340228 1450130_at 1 81.6 cM chr1:157126726-157127275 1 G3 chr1:157122786-157264574 1 G3 RSQ Mm.266215 NM_011273 1 1 19775 Xpr1 xenotropic and polytropic retrovirus receptor 1 (Xpr1), mRNA. integral to membrane;; membrane;; plasma membrane;; receptor activity;; response to virus;; response to virus cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity multi-organism process;; response to stimulus response to biotic stimulus;; response to other organism 58.8742 61.2051 70.7522 165.0964 155.4819 153.3741 0.0012303923 -1.31628 5.98662 7.30289 1348619 1450241_a_at 11 46.13 cM chr11:79340425-79340856 11 B5 chr11:79340061-79344111 11 B5 RSQ Mm.439665 NM_010161 2 1 14017 RP23-271B20.1 Evi2a ecotropic viral integration site 2a (Evi2a), transcript variant 2, mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 37.7950 28.2764 33.1230 90.4048 83.3322 128.0871 0.0038734357 -1.58957 5.03714 6.62670 1348652 1450344_a_at 3 82.0 cM chr3:157307126-157307682 3 H4 chr3:157229855-157307722 3 H4 RSQ Mm.30424 NM_011196 1 1 19218 Ptger3 prostaglandin E receptor 3 (subtype EP3) (Ptger3), mRNA. Eicosanoid Metabolism Calcium signaling pathway;; Neuroactive ligand-receptor interaction CLASS Environmental Information Processing; Signal Transduction; Calcium signaling pathway [PATH:mmu04020] Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger;; bicarbonate transport;; diuresis;; elevation of cytosolic calcium ion concentration;; fever;; fever;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; G-protein signaling, coupled to cAMP nucleotide second messenger;; integral to membrane;; membrane;; plasma membrane;; prostaglandin E receptor activity;; prostaglandin E receptor activity;; prostaglandin receptor activity;; protein binding;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; establishment of localization;; localization;; multicellular organismal process;; regulation of biological process;; response to stimulus cell communication;; cellular homeostasis;; establishment of localization;; regulation of biological process;; regulation of biological quality;; regulation of body fluid levels;; regulation of cellular process;; regulation of molecular function;; response to external stimulus;; response to stress;; system process;; temperature homeostasis;; transport 1071.1847 1089.5250 1010.0007 2497.9299 2426.5297 3175.8699 0.0054799905 -1.34317 10.04487 11.38804 1340882 1451015_at 14 chr14:31383452-31386610 14 B chr14:31362334-31387908 14 B RSQ Mm.290692 NM_009388 1 1 21881 Tkt transketolase (Tkt), mRNA. Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [PATH:mmu00030] Metabolism; Biosynthesis of Polyketides and Nonribosomal Peptides; Biosynthesis of ansamycins;; Pentose phosphate pathway calcium ion binding;; catalytic activity;; metabolic process;; metal ion binding;; regulation of growth;; transferase activity;; transketolase activity binding;; catalytic activity ion binding;; transferase activity biological regulation;; growth;; metabolic process;; regulation of biological process regulation of biological process;; regulation of growth 151.9955 167.2135 163.0853 250.2095 346.0062 433.6498 0.040411285 -1.05971 7.32764 8.38734 1340915 1451054_at 4 31.4 cM chr4:63005700-63007115 4 B3 chr4:63005599-63009196 4 B3 RSQ Mm.4777 NM_008768 1 1 18405 Orm1 orosomucoid 1 (Orm1), mRNA. acute-phase response;; binding;; extracellular region;; extracellular space;; regulation of immune system process;; transport;; transporter activity extracellular region;; extracellular region part extracellular region part;; extracellular space binding;; transporter activity biological regulation;; establishment of localization;; immune system process;; localization;; regulation of biological process;; response to stimulus establishment of localization;; regulation of biological process;; regulation of immune system process;; response to external stimulus;; response to stress;; transport 997.4611 919.0831 887.0660 2245.5578 2050.1021 3328.9561 0.018062669 -1.41204 9.86636 11.27840 1341334 1451666_at 11 chr11:100337916-100338433 11 D chr11:100337669-100389215 11 D RSQ Mm.282039 NM_134037 1 1 104112 RP23-392I3.9 Acly ATP citrate lyase (Acly), mRNA. Shuttle for transfer of acetyl groups from mitochondria to the cytosol Citrate cycle (TCA cycle);; Metabolic pathways CLASS Metabolism; Carbohydrate Metabolism; Citrate cycle (TCA cycle) [PATH:mmu00020] Metabolism; Energy Metabolism; Reductive carboxylate cycle (CO2 fixation) [PATH:mmu00720];; Reductive carboxylate cycle (CO2 fixation) acetyl-CoA biosynthetic process;; ATP binding;; ATP citrate synthase activity;; binding;; catalytic activity;; cellular carbohydrate metabolic process;; cytoplasm;; intracellular;; lipid biosynthetic process;; lyase activity;; magnesium ion binding;; metabolic process;; metal ion binding;; nucleotide binding;; protein binding;; succinate-CoA ligase (ADP-forming) activity;; transferase activity;; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; ligase activity;; lyase activity;; nucleoside binding;; nucleotide binding;; protein binding;; transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; primary metabolic process 57.6680 62.2610 78.6925 120.6347 169.9424 195.6806 0.010009851 -1.27588 6.03604 7.31192 1341346 1451679_at X chrX:132568984-132569483 X F1 chrX:132567905-132569483 X F1 RSQ NR_003641 1 1 76219 6530401D17Rik RIKEN cDNA 6530401D17 gene (6530401D17Rik), non-coding RNA. 327.9297 381.4167 391.3918 858.9852 657.3160 727.5383 0.0026324184 -1.02296 8.51498 9.53794 1349018 1451683_x_at 17 B1|17 18.44 cM UG5 Mm.439675 14972 H2-K1 MRNA similar to histocompatibility 2, D region locus 1 (cDNA clone MGC:25703 IMAGE:3675316) Allograft rejection;; Antigen processing and presentation;; Autoimmune thyroid disease;; Cell adhesion molecules (CAMs);; Endocytosis;; Graft-versus-host disease CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Transport and Catabolism; Endocytosis [PATH:mmu04144] Cellular Processes; Immune System; Natural killer cell mediated cytotoxicity [PATH:mmu04650] Cellular Processes; Immune System;;; Natural killer cell mediated cytotoxicity;; Type I diabetes mellitus antigen processing and presentation;; antigen processing and presentation of exogenous peptide antigen via MHC class I;; antigen processing and presentation of peptide antigen via MHC class I;; defense response to bacterium;; external side of plasma membrane;; immune response;; integral to membrane;; membrane;; MHC class I protein complex;; peptide antigen binding;; positive regulation of T cell mediated cytotoxicity cell;; cell part;; macromolecular complex cell part;; cell surface;; membrane;; membrane part;; protein complex binding antigen binding;; peptide binding biological regulation;; cell killing;; cellular process;; death;; developmental process;; immune system process;; multi-organism process;; positive regulation of biological process;; regulation of biological process;; response to stimulus antigen processing and presentation;; cell death;; immune effector process;; immune response;; leukocyte mediated cytotoxicity;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; positive regulation of response to stimulus;; regulation of biological process;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of response to stimulus;; response to biotic stimulus;; response to other organism;; response to stress 1170.2803 1025.6796 1004.8186 1601.8713 3039.6844 2725.6312 0.049327614 -1.15330 10.05591 11.20921 1349251 1452406_x_at RSQ Mm.391385 NM_133362 1 1 170942 Erdr1 erythroid differentiation regulator 1 (Erdr1), mRNA. 261.2908 217.2031 246.6519 939.6733 724.9297 829.1106 0.00031471617 -1.77813 7.91292 9.69104 1349261 1452431_s_at 17 B1|17 18.65 cM UGA Mm.235338 14960 H2-Aa Histocompatibility 2, class II antigen A, alpha, mRNA (cDNA clone MGC:25391 IMAGE:3670758) Allograft rejection;; Antigen processing and presentation;; Asthma;; Autoimmune thyroid disease;; Cell adhesion molecules (CAMs);; Graft-versus-host disease CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Immune System; Antigen processing and presentation [PATH:mmu04612] Human Diseases; Immune Disorders; Asthma [PATH:mmu05310] Human Diseases; Immune Disorders; Systemic lupus erythema;; Systemic lupus erythematosus;; Type I diabetes mellitus antigen processing and presentation;; antigen processing and presentation of exogenous peptide antigen via MHC class II;; antigen processing and presentation of peptide antigen;; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;; external side of plasma membrane;; immune response;; integral to membrane;; lysosome;; membrane;; MHC class II protein complex;; peptide antigen binding;; plasma membrane;; positive regulation of T cell differentiation;; protein binding cell;; cell part;; macromolecular complex;; organelle cell part;; cell surface;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; protein complex binding antigen binding;; peptide binding;; protein binding biological regulation;; cellular process;; developmental process;; immune system process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; antigen processing and presentation;; cell activation;; cellular developmental process;; immune response;; immune system development;; leukocyte activation;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of multicellular organismal process 44.7097 48.4795 47.4463 92.4934 108.4380 86.5265 0.0043629784 -1.02568 5.55001 6.57569 1349327 1452583_s_at 17 chr17:80584095-80584282 17 E3 chr17:80526810-80584372 17 E3 RSQ Mm.29098 NM_176963 1 1 319625 Galm galactose mutarotase (Galm), mRNA. Glycolysis / Gluconeogenesis CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis [PATH:mmu00010] aldose 1-epimerase activity;; carbohydrate binding;; carbohydrate metabolic process;; catalytic activity;; cytoplasm;; hexose metabolic process;; isomerase activity;; protein homodimerization activity cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity carbohydrate binding;; isomerase activity;; protein binding metabolic process alcohol metabolic process;; primary metabolic process 81.5042 91.0702 93.8270 175.9797 191.9577 235.9697 0.0039618965 -1.17224 6.46988 7.64212 1342085 1452899_at 12 F1|12 54.5 cM UGA Mm.293263 75745 Rian MRNA, MBII-343 snoRNA nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle 140.5245 139.6971 127.6174 625.5690 704.2230 826.8130 0.00074486461 -2.39460 7.08551 9.48011 1342546 1455918_at 8 10.0 cM chr8:28336344-28336821 8 A2 IPA Adrb3 adrenergic receptor, beta 3 214.2176 215.9003 238.9542 493.6886 411.4053 502.5414 0.0017413234 -1.06908 7.79925 8.86832 1342795 1460173_at 11 56.0 cM chr11:97699504-97699690 11 D chr11:97660985-97700078 11 D RSQ Mm.271967 NM_010688 1 1 16796 RP23-386E10.6 Lasp1 LIM and SH3 protein 1 (Lasp1), mRNA. actin binding;; actin filament binding;; cytoplasm;; cytoskeleton;; focal adhesion;; ion transport;; metal ion binding;; protein binding;; transport;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle binding ion binding;; protein binding establishment of localization;; localization establishment of localization;; transport 153.1382 148.9297 128.5013 296.8894 284.2300 301.5964 0.0029006027 -1.03945 7.16094 8.20039 1370785 1419985_s_at 11 28.5 cM chr11:54863346-54863586 11 B1.3 chr11:54863239-54891633 11 B1.3 RSQ Mm.22361 NM_177471 1 1 52570 Ccdc69 coiled-coil domain containing 69 (Ccdc69), mRNA. 474.2630 477.2828 472.6945 1113.3022 904.7566 1598.5856 0.032205525 -1.30386 8.89100 10.19487 1350368 1428190_at 16 10.65 cM chr16:17925667-17925845 16 A3 chr16:17925303-17928312 16 A3 RSQ Mm.229291 NM_153150 1 1 13358 Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 (Slc25a1), nuclear gene encoding mitochondrial protein, mRNA. Shuttle for transfer of acetyl groups from mitochondria to the cytosol integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part establishment of localization;; localization establishment of localization;; transport 526.5408 545.4004 553.0658 1091.2918 1637.4404 1664.8059 0.018493841 -1.40910 9.08096 10.49006 1350720 1428821_at 2 A3 chr2:26448641-26449174 2 A3 UGA Mm.24244 67512 RP23-125H15.1 Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), mRNA Ether lipid metabolism;; Glycerolipid metabolism;; Glycerophospholipid metabolism;; Metabolic pathways CLASS Metabolism; Lipid Metabolism; Glycerolipid metabolism [PATH:mmu00561] Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:mmu00564] Metabolism; Lipid Metabolism; Ether lipid metabolism [PATH:mmu00565] 1-acylglycerol-3-phosphate O-acyltransferase activity;; acyltransferase activity;; endoplasmic reticulum;; integral to membrane;; membrane;; metabolic process;; phospholipid biosynthetic process;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; organophosphate metabolic process;; primary metabolic process 83.4715 77.0000 72.4800 173.2064 154.9167 172.0175 0.0001655887 -1.10287 6.27650 7.37937 1351306 1429679_at 5 chr5:21080798-21081258 5 A3 chr5:21049344-21081729 5 A3 RSQ Mm.439963 NM_028977 1 1 74511 Lrrc17 leucine rich repeat containing 17 (Lrrc17), mRNA. protein binding binding protein binding 35.5440 31.2393 35.1483 92.3557 67.4359 70.8265 0.0067677331 -1.16620 5.08407 6.25026 1351521 1429954_at 6 chr6:122917515-122919822 6 F2 chr6:122902661-122919892 6 F2 RSQ Mm.25684 NM_153197 1 1 73149 Clec4a3 C-type lectin domain family 4, member a3 (Clec4a3), mRNA. integral to membrane;; membrane;; receptor activity;; sugar binding cell;; cell part cell part;; membrane;; membrane part binding;; molecular transducer activity carbohydrate binding;; signal transducer activity 295.5887 322.3900 337.6717 837.8303 1440.6726 1744.2968 0.021204072 -2.01063 8.31320 10.32382 1370950 1430584_s_at 3 A2|3 11.7 cM chr3:14865376-14865506 3 A1 UGA Mm.300 12350 Car3 Carbonic anhydrase 3, mRNA (cDNA clone MGC:18583 IMAGE:4195712) Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] carbonate dehydratase activity;; cytoplasm;; lyase activity;; metal ion binding;; nickel ion binding;; one-carbon metabolic process;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 95.2206 74.5342 80.9407 130.5938 183.7836 207.7039 0.019220843 -1.03912 6.37728 7.41640 1371114 1432489_a_at 15 chr15:57979902-57985205 15 D1 chr15:57972990-57990209 15 D1 RSQ Mm.26771 NM_029734 1 1 76773 Wdyhv1 WDYHV motif containing 1 (Wdyhv1), mRNA. cytosol;; nucleus;; protein catabolic process;; protein modification process;; protein N-terminal glutamine amidohydrolase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 26.9117 32.0852 35.0977 57.9109 66.5614 66.3859 0.0032457903 -1.02596 4.96243 5.98839 1371142 1433716_x_at 14 D3-E1 chr14:71379255-71379626 14 D2 UG5 Mm.32619 14586 Gfra2 Glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2), mRNA anchored to membrane;; membrane;; nervous system development;; plasma membrane;; receptor activity;; transmembrane receptor protein tyrosine kinase signaling pathway cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 102.6417 97.0494 92.2826 235.8176 229.9281 309.1894 0.0054191919 -1.39627 6.60337 7.99964 1354344 1433885_at 13 47.01 cM chr13:96397192-96397709 13 D1 chr13:96397131-96661877 13 D1 RSQ Mm.38878 NM_027711 1 1 544963 Iqgap2 IQ motif containing GTPase activating protein 2 (Iqgap2), mRNA. calmodulin binding;; GTPase activator activity;; intracellular;; protein binding;; regulation of small GTPase mediated signal transduction cell;; cell part cell part;; intracellular binding;; enzyme regulator activity enzyme activator activity;; nucleoside-triphosphatase regulator activity;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 814.3356 767.7958 731.3685 1546.9073 1505.3570 2000.9759 0.0078644728 -1.11635 9.58950 10.70585 1354501 1434185_at 11 chr11:84214703-84215129 11 C chr11:84008939-84215153 11 C RSQ Mm.31374 NM_133360 2 2 107476 RP23-123O10.1 Acaca acetyl-Coenzyme A carboxylase alpha (Acaca), mRNA. Fatty acid biosynthesis;; Insulin signaling pathway CLASS Metabolism; Carbohydrate Metabolism; Pyruvate metabolism [PATH:mmu00620] Metabolism; Carbohydrate Metabolism; Propanoate metabolism [PATH:mmu00640] Metabolism; Lipid Metabolism; Fatty acid biosynthesis [PATH:mmu00061] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910];; Metabolic pathways;; Propanoate metabolism;; Pyruvate metabolism acetyl-CoA carboxylase activity;; ATP binding;; biotin binding;; biotin carboxylase activity;; catalytic activity;; cytoplasm;; fatty acid biosynthetic process;; ligase activity;; lipid biosynthetic process;; lipid homeostasis;; lipid metabolic process;; manganese ion binding;; metabolic process;; metal ion binding;; multicellular organismal protein metabolic process;; nucleotide binding;; protein binding;; tissue homeostasis cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity carboxylic acid binding;; ion binding;; ligase activity;; nucleoside binding;; nucleotide binding;; protein binding;; vitamin binding biological regulation;; cellular process;; metabolic process;; multicellular organismal process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal homeostasis;; multicellular organismal metabolic process;; primary metabolic process;; regulation of biological quality 41.6835 44.6629 35.8108 84.0888 96.8739 116.9309 0.0025357662 -1.27889 5.34158 6.62046 1354564 1434301_at 15 chr15:60650930-60651452 15 D1 chr15:60650550-60656635 15 D1 RSQ NM_001162926 1 1 399603 D330050I23Rik RIKEN cDNA D330050I23 gene (D330050I23Rik), mRNA. 247.0080 249.6608 232.8227 454.1377 488.5551 518.3594 0.00040703644 -1.00061 7.92511 8.92572 1354940 1435031_at 5 chr5:136211374-136212331 5 G2 chr5:136211359-136220042 5 G2 RSQ Mm.11688 NM_172541 1 1 215210 Tmem120a transmembrane protein 120A (Tmem120a), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 50.9001 52.2348 54.1234 98.9947 197.6991 244.4297 0.049937484 -1.68500 5.71157 7.39657 1355930 1436590_at 8 chr8:36450642-36451011 8 A4 chr8:36438794-36451193 8 A4 RSQ Mm.247126 NM_177741 1 1 244416 Ppp1r3b protein phosphatase 1, regulatory (inhibitor) subunit 3B (Ppp1r3b), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] carbohydrate metabolic process;; glycogen metabolic process cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 67.2663 71.3168 70.0025 104.6075 180.3644 172.4665 0.048054528 -1.09216 6.11911 7.21126 1356002 1436702_at 5 chr5:34338632-34348565 5 B2 RSQ Mm.274610 NM_001001985 1 1 269642 Nat8l N-acetyltransferase 8-like (Nat8l), mRNA. acyltransferase activity;; integral to membrane;; membrane;; metabolic process;; N-acetyltransferase activity;; transferase activity cell;; cell part cell part;; membrane;; membrane part catalytic activity transferase activity metabolic process 44.4701 36.4406 38.4622 113.6123 82.3965 102.5717 0.0025047374 -1.31512 5.30920 6.62432 1356037 1436779_at X chrX:9013285-9013716 X A1.1 chrX:9012377-9046450 X A1.1 RSQ Mm.200362 NM_007807 1 1 13058 RP23-243O4.1 Cybb cytochrome b-245, beta polypeptide (Cybb), mRNA. Leukocyte transendothelial migration CLASS Cellular Processes; Immune System; Leukocyte transendothelial migration [PATH:mmu04670] cytoplasm;; electron carrier activity;; electron transport chain;; FAD binding;; hydrogen peroxide biosynthetic process;; integral to membrane;; ion channel activity;; ion transport;; iron ion binding;; membrane;; metal ion binding;; mitochondrion;; oxidation reduction;; oxidoreductase activity;; plasma membrane;; transport;; voltage-gated ion channel activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity;; electron carrier activity;; transporter activity cofactor binding;; ion binding;; nucleoside binding;; nucleotide binding;; oxidoreductase activity;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process biosynthetic process;; cellular metabolic process;; establishment of localization;; oxidation reduction;; transport 48.3358 47.2480 52.0885 112.1908 115.9695 128.2543 0.00011130469 -1.27006 5.62003 6.89009 1356239 1437213_at 8 chr8:96542029-96542261 8 C5 UG5 Mm.432689 Transcribed locus 68.5479 59.5045 63.3984 121.9304 136.0256 201.8644 0.024362556 -1.23152 5.99345 7.22496 1371329 1437479_x_at 5 65.0 cM chr5:120134159-120134242 5 F chr5:120120677-120134610 5 F RSQ Mm.219139 NM_198052 2 1 21386 Tbx3 T-box 3 (Tbx3), transcript variant 2, mRNA. blood vessel development;; branching involved in mammary gland duct morphogenesis;; cell aging;; DNA binding;; forelimb morphogenesis;; heart looping;; heart morphogenesis;; in utero embryonic development;; limb morphogenesis;; limbic system development;; mammary gland development;; mammary placode formation;; mammary placode formation;; multicellular organismal development;; negative regulation of transcription;; negative regulation of transcription, DNA-dependent;; nucleus;; organ morphogenesis;; positive regulation of transcription, DNA-dependent;; regulation of cell proliferation;; regulation of transcription, DNA-dependent;; specification of organ position;; transcription;; transcription factor activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription factor activity;; transcription repressor activity anatomical structure formation;; biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process aging;; anatomical structure development;; anatomical structure formation involved in morphogenesis;; anatomical structure morphogenesis;; biosynthetic process;; cell aging;; cell proliferation;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 26.7341 27.4372 27.1340 58.6026 57.1946 58.9143 5.2734902e-07 -1.10352 4.76023 5.86375 1371345 1437811_x_at 8 E1 UGA Mm.393405 72042 Cotl1 Coactosin-like 1 (Dictyostelium) (Cotl1), mRNA actin binding;; cytoplasm;; cytoskeleton;; intracellular;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding protein binding 219.4476 189.3013 182.7630 501.5173 602.0631 612.3131 0.00025841882 -1.53532 7.61870 9.15402 1356810 1438285_at 11 A1 chr11:5681352-5681850 11 A1 UGA Mm.260203 76508 2210015D19Rik PREDICTED: Mus musculus RIKEN cDNA 2210015D19 gene, transcript variant 2 (2210015D19Rik), mRNA 17.9538 18.2423 20.8772 31.6523 45.1828 46.2399 0.01540413 -1.09124 4.24643 5.33767 1356824 1438309_at 2 C1.1 chr2:58120038-58120425 2 C1.1 UG5 Mm.77751 269275 RP23-100B18.1 Acvr1c Activin A receptor, type IC, mRNA (cDNA clone IMAGE:1196242) Adherens junction;; Chronic myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway [PATH:mmu04010] Environmental Information Processing; Signal Transduction; TGF-beta signaling pathway [PATH:mmu04350] Environmental Information Processing; Signaling Molecules and Interaction; Cytokine-cytokine receptor interaction [PATH:mmu0;; Colorectal cancer;; Endocytosis;; MAPK signaling pathway;; Pancreatic cancer;; Pathways in cancer;; TGF-beta signaling pathway activin binding;; apoptosis;; ATP binding;; cell surface;; determination of left/right symmetry;; in utero embryonic development;; integral to membrane;; kinase activity;; lipid storage;; magnesium ion binding;; manganese ion binding;; membrane;; metal ion binding;; negative regulation of insulin secretion;; nucleotide binding;; positive regulation of apoptosis;; protein amino acid phosphorylation;; protein kinase activity;; protein serine/threonine kinase activity;; receptor activity;; response to dietary excess;; response to glucose stimulus;; response to insulin stimulus;; transferase activity;; transforming growth factor beta receptor activity;; transmembrane receptor protein serine/threonine kinase activity;; trophectodermal cell proliferation cell;; cell part cell part;; cell surface;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity ion binding;; nucleoside binding;; nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; death;; developmental process;; establishment of localization;; growth;; localization;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; cell communication;; cell death;; cell proliferation;; cellular localization;; cellular metabolic process;; developmental growth;; embryonic development;; establishment of localization;; establishment of localization in cell;; generation of a signal involved in cell-cell signaling;; macromolecule localization;; macromolecule metabolic process;; multicellular organism growth;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of transport;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of localization;; regulation of multicellular organismal process;; response to chemical stimulus;; response to dietary excess;; response to endogenous stimulus;; secretion by cell;; transport 92.0541 79.6849 100.0685 144.2529 185.0408 226.9684 0.017782834 -1.01500 6.49516 7.51017 1356879 1438411_at 5 chr5:124327047-124327571 5 F chr5:124326986-124330012 5 F RSQ Mm.33362 NM_175520 1 1 243270 Gpr81 G protein-coupled receptor 81 (Gpr81), mRNA. G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; plasma membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 164.5932 184.6137 207.6188 326.1093 438.2180 438.9162 0.0046496634 -1.10453 7.52964 8.63417 1357007 1438664_at 12 chr12:32643802-32643933 12 A3 chr12:32643343-32746144 12 A3 RSQ Mm.476869 NM_011158 1 1 19088 RP23-193M19.1 Prkar2b protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), mRNA. AKAP95 role in mitosis and chromosome dynamics;; Protein Kinase A at the Centrosome;; Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation Apoptosis;; Insulin signaling pathway CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] cAMP binding;; cAMP-dependent protein kinase complex;; cAMP-dependent protein kinase regulator activity;; cell proliferation;; fatty acid metabolic process;; kinase activity;; learning;; nucleotide binding;; organ morphogenesis;; protein amino acid phosphorylation;; regulation of protein amino acid phosphorylation;; signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity kinase regulator activity;; nucleoside binding;; nucleotide binding;; transferase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; behavior;; cell communication;; cell proliferation;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; system process 106.3928 109.4516 109.5074 313.2228 238.8955 280.8846 0.0064046775 -1.34761 6.76076 8.10837 1357038 1438720_at 10 chr10:28949419-28949955 10 A4 UG5 Mm.379334 Transcribed locus 22.5993 22.3923 18.8778 40.9233 80.3196 74.9426 0.02976068 -1.56283 4.40725 5.97008 1357453 1439489_at 19 chr19:38188168-38188602 19 C3 chr19:38171568-38188753 19 C2 RSQ Mm.35288 NM_181748 1 1 107221 Gpr120 G protein-coupled receptor 120 (Gpr120), mRNA. endocytic vesicle;; fatty acid binding;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; hormone secretion;; integral to membrane;; lipid binding;; membrane;; plasma membrane;; receptor activity;; signal transducer activity;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; vesicle binding;; molecular transducer activity carboxylic acid binding;; lipid binding;; signal transducer activity biological regulation;; cellular process;; establishment of localization;; localization;; regulation of biological process cell communication;; cellular localization;; establishment of localization;; establishment of localization in cell;; generation of a signal involved in cell-cell signaling;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; secretion by cell;; transport 15.0958 13.2232 14.5463 88.3494 153.0361 154.0390 0.00527146 -3.16212 3.83455 6.99668 1357529 1439575_at 17 chr17:65605344-65890122 17 E1.1 RSQ Mm.141275 NM_001008973 1 1 381107 E130009J12Rik RIKEN cDNA E130009J12 gene (E130009J12Rik), mRNA. 556.9391 549.7219 553.4852 1556.7029 1156.1628 1112.1309 0.016155043 -1.18739 9.11211 10.29951 1357783 1439859_at 6 chr6:127035208-127035696 6 F3 chr6:127035139-127059554 6 F3 RSQ Mm.101836 NM_177003 2 2 319801 9630033F20Rik RIKEN cDNA 9630033F20 gene (9630033F20Rik), mRNA. catalytic activity;; fructose-2,6-bisphosphate 2-phosphatase activity;; hydrolase activity;; metabolic process catalytic activity hydrolase activity metabolic process 58.7067 51.7139 47.5119 119.9255 112.5955 92.1749 0.0025297024 -1.03638 5.71272 6.74910 1358871 1441071_at 1 chr1:21950022-21950404 1 A4 UG5 Mm.403737 Transcribed locus, strongly similar to XP_532200.2 PREDICTED: similar to potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 1 [Canis familiaris] 186.1101 193.3616 192.3153 416.1203 548.2478 539.1323 0.0076936342 -1.38385 7.57417 8.95801 1358895 1441096_at 11 chr11:76511606-76512085 11 B5 chr11:76493374-76512164 11 B5 RSQ Mm.127006 NM_177709 1 1 237858 RP23-343C18.2 Tusc5 tumor suppressor candidate 5 (Tusc5), mRNA. integral to membrane;; membrane;; response to biotic stimulus cell;; cell part cell part;; membrane;; membrane part response to stimulus response to biotic stimulus 68.6128 64.9249 62.4214 177.0561 146.8189 190.7301 0.0031168307 -1.38542 6.02836 7.41378 1360916 1443353_at chr15:12060176-12060481 15 A1 IPA ESTs, Weakly similar to RIKEN cDNA 5730493B19 [Mus musculus] [M.musculus] 177.1850 168.0816 178.2110 420.4297 438.7405 396.6601 5.5423271e-05 -1.26171 7.44652 8.70823 1362970 1445574_at 18 chr18:61451167-61451464 18 E1 UGA Mm.25466 Transcribed locus 28.8852 26.2278 36.4593 57.5168 83.0667 58.6735 0.0082293457 -1.11441 4.91783 6.03225 1364513 1447174_at 14 chr14:98494912-98495320 14 E2.1 UGA Mm.416176 Transcribed locus 73.4950 77.6659 68.1541 177.1183 253.5899 217.0947 0.0046209341 -1.54920 6.18984 7.73903 1371969 1447584_s_at 10 chr10:4739804-4739954 10 A1 chr10:4739751-4752813 10 A1 RSQ Mm.338242 NM_026793 1 1 68632 Myct1 myc target 1 (Myct1), mRNA. integral to membrane;; membrane;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle 49.1210 44.3139 41.1772 92.0591 144.0671 189.2351 0.02824509 -1.60246 5.48391 7.08637 1365656 1453588_at 3 A2|3 11.7 cM chr3:14865268-14865776 3 A1 UGA Mm.300 12350 Car3 Carbonic anhydrase 3, mRNA (cDNA clone MGC:18583 IMAGE:4195712) Nitrogen metabolism CLASS Metabolism; Energy Metabolism; Nitrogen metabolism [PATH:mmu00910] carbonate dehydratase activity;; cytoplasm;; lyase activity;; metal ion binding;; nickel ion binding;; one-carbon metabolic process;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity ion binding;; lyase activity cellular process;; metabolic process cellular metabolic process 27.5075 23.9333 27.4346 68.3508 54.4139 63.0029 0.00083551192 -1.23250 4.71354 5.94604 1365660 1453593_at 16 chr16:65861625-65861853 16 C1.3 chr16:65815877-65863311 16 C1.3 RSQ Mm.25670 XM_283372 2 1 73569 Vgll3 PREDICTED: vestigial like 3 (Drosophila) (Vgll3), mRNA. nucleus;; regulation of transcription;; regulation of transcription, DNA-dependent;; transcription;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle transcription regulator activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 160.4480 173.8766 180.2793 370.8558 344.0756 389.4342 0.00010721953 -1.10152 7.42066 8.52218 1366445 1454671_at 5 B1 chr5:28404633-28405164 5 B1 UG5 Mm.30221 231070 Insig1 Insulin induced gene 1 (Insig1), mRNA cholesterol biosynthetic process;; cholesterol metabolic process;; cranial suture morphogenesis;; endoplasmic reticulum;; inner ear morphogenesis;; integral to membrane;; lipid metabolic process;; membrane;; middle ear morphogenesis;; negative regulation of fat cell differentiation;; negative regulation of fatty acid biosynthetic process;; negative regulation of steroid biosynthetic process;; palate development;; protein binding;; response to sterol depletion;; steroid metabolic process;; sterol biosynthetic process;; triglyceride metabolic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process;; response to stimulus alcohol metabolic process;; anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular developmental process;; cellular metabolic process;; embryonic development;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; organic ether metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to stress 46.1979 36.3080 43.9885 123.3106 117.1716 126.1256 0.0025980339 -1.54211 5.39034 6.93245 1366550 1454877_at 1 chr1:194670735-194671190 1 H6 chr1:194670681-194681915 1 H6 RSQ Mm.22806 NM_198247 1 1 214791 RP23-381K21.1 Sertad4 SERTA domain containing 4 (Sertad4), mRNA. 31.5324 33.4904 29.9236 81.8681 65.0026 53.3577 0.021579116 -1.05588 4.98255 6.03843 1366597 1454965_at 2 chr2:83723050-83723465 2 D chr2:83649896-83723691 2 D RSQ XM_922613 1 1 634842 LOC634842 PREDICTED: similar to D430039N05Rik protein, transcript variant 2 (LOC634842), mRNA. 166.0027 143.3408 143.8669 354.7032 306.4024 354.5955 0.00029954228 -1.16427 7.23565 8.39993 1372388 1455966_s_at 8 chr8:96541804-96542041 8 C5 UGA Mm.432689 Transcribed locus 131.5357 156.7280 165.4637 245.9247 373.0138 374.7883 0.016848462 -1.11110 7.23393 8.34503 1372415 1456475_s_at 12 chr12:32643573-32643806 12 A3 chr12:32643343-32746144 12 A3 RSQ Mm.476869 NM_011158 1 1 19088 RP23-193M19.1 Prkar2b protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), mRNA. AKAP95 role in mitosis and chromosome dynamics;; Protein Kinase A at the Centrosome;; Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation Apoptosis;; Insulin signaling pathway CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] cAMP binding;; cAMP-dependent protein kinase complex;; cAMP-dependent protein kinase regulator activity;; cell proliferation;; fatty acid metabolic process;; kinase activity;; learning;; nucleotide binding;; organ morphogenesis;; protein amino acid phosphorylation;; regulation of protein amino acid phosphorylation;; signal transduction cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; protein complex binding;; catalytic activity;; enzyme regulator activity kinase regulator activity;; nucleoside binding;; nucleotide binding;; transferase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; behavior;; cell communication;; cell proliferation;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; system process 160.4410 163.4505 162.1254 526.1544 357.2980 340.6341 0.022270292 -1.30428 7.33986 8.64414 1368361 1457587_at 1 chr1:21388534-21388877 1 A4 chr1:21388483-21952023 1 A4 RSQ Mm.336519 NM_023872 2 1 226922 Kcnq5 potassium voltage-gated channel, subfamily Q, member 5 (Kcnq5), mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 67.4694 81.8275 72.7446 183.5943 170.8214 134.1250 0.0044111187 -1.12957 6.20515 7.33472 1369047 1458379_at 10 A4 chr10:28947684-28948074 10 A4 UGA Mm.132789 212448 9330159F19Rik RIKEN cDNA 9330159F19 gene, mRNA (cDNA clone IMAGE:8861298) 10.4432 15.4484 13.6507 33.3623 17.8815 32.1740 0.049283963 -1.04119 3.70159 4.74279 1372680 1459973_x_at 2 C2-D|2 35.0 cM UG5 Mm.1151 13482 RP23-87G8.2 Dpp4 Dipeptidylpeptidase 4, mRNA (cDNA clone MGC:14076 IMAGE:3982742) aminopeptidase activity;; extracellular region;; hydrolase activity;; integral to membrane;; intercellular canaliculus;; membrane;; peptidase activity;; plasma membrane;; proteolysis;; serine-type endopeptidase activity;; serine-type peptidase activity cell;; cell part;; extracellular region cell part;; membrane;; membrane part catalytic activity hydrolase activity metabolic process catabolic process;; macromolecule metabolic process;; primary metabolic process