A 1 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen A 2 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen A 3 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen A 4 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen A 5 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen A 6 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen B 7 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen B 8 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen B 9 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen B 10 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen B 11 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen B 12 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen C 13 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen C 14 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen C 15 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen C 16 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen C 17 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen C 18 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Gene Property Filtering 18 arrays and 45101 genes in the input dataset 18 arrays and 36 genes in the output dataset. 45065 genes excluded for Well ID not being in local list 'EG3-2-test-1+FC'. A A A A A A B B B B B B C C C C C C 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M42 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M43 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M44 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M47 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M48 GSP-EG003.1 Hennighausen 02-09-07_Hennighausen_PK_Mouse430_2_M50 GSP-EG003.1 Hennighausen 06-10-08_Hennighausen_1PK_Mouse430_2_4038WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_2PK_Mouse430_2_4060WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_3PK_Mouse430_2_4063WT GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_4PK_Mouse430_2_4035KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_5PK_Mouse430_2_4036KO GSP-EG003.2 Hennighausen 06-10-08_Hennighausen_6PK_Mouse430_2_4042KO GSP-EG003.2 Hennighausen Well ID Feature ID Map mgB37_Probe Chr:Start-Stop mgB37_Probe Cytoband mgB37_RefSeq Chr:Start-Stop mgB37_RefSeq Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 53.9805 60.7781 50.3236 51.8402 50.3162 40.0145 76.3389 89.8983 262.7482 224.6651 88.4559 227.8496 157.9852 183.0014 287.4398 85.9731 78.4342 65.4170 1328794 1417312_at 7 chr7:119260710-119261088 7 F1 chr7:119259532-119302571 7 F1 RSQ Mm.55143 NM_015814 1 1 50781 Dkk3 dickkopf homolog 3 (Xenopus laevis) (Dkk3), mRNA. extracellular region;; extracellular space;; multicellular organismal development;; negative regulation of Wnt receptor signaling pathway;; Wnt receptor signaling pathway extracellular region;; extracellular region part extracellular region part;; extracellular space biological regulation;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process cell communication;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 22.9933 21.2014 23.2580 23.9194 26.5585 26.6697 26.8275 24.5152 152.6904 106.3417 30.6207 92.1240 55.3328 113.4937 92.1606 32.1468 27.0840 25.6622 1329031 1417597_at 1 30.1 cM chr1:60826814-60827346 1 C2 chr1:60803231-60830203 1 C2 RSQ Mm.255003 NM_007642 2 2 12487 CH29-189K17.3 Cd28 CD28 antigen (Cd28), mRNA. Antigen Dependent B Cell Activation;; Bystander B Cell Activation;; HIV Induced T Cell Apoptosis;; Role of Tob in T-cell activation;; Selective expression of chemokine receptors during T-cell polarization;; T Cytotoxic Cell Surface Molecules;; T Helper Cell Surface Molecules;; Th1/Th2 Differentiation;; The Co-Stimulatory Signal During T-cell Activation Allograft rejection;; Autoimmune thyroid disease;; Cell adhesion molecules (CAMs);; Graft-versus-host disease CLASS Environmental Information Processing; Signaling Molecules and Interaction; Cell adhesion molecules (CAMs) [PATH:mmu04514] Cellular Processes; Immune System; T cell receptor signaling pathway [PATH:mmu04660] Human Diseases; Immune Disorders; Systemic lupus erythematosus [PATH:mmu05322] Human Diseases; Immune Disorders; Aut;; Systemic lupus erythematosus;; T cell receptor signaling pathway;; Type I diabetes mellitus external side of plasma membrane;; external side of plasma membrane;; external side of plasma membrane;; immune response;; induction of apoptosis by extracellular signals;; integral to membrane;; membrane;; negative thymic T cell selection;; plasma membrane;; positive regulation of alpha-beta T cell proliferation;; positive regulation of alpha-beta T cell proliferation;; positive regulation of inflammatory response to antigenic stimulus;; positive regulation of interleukin-2 biosynthetic process;; positive regulation of isotype switching to IgG isotypes;; positive regulation of T cell proliferation;; positive regulation of T cell proliferation;; T cell costimulation;; T cell costimulation cell;; cell part cell part;; cell surface;; membrane;; membrane part biological regulation;; cellular process;; death;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; immune effector process;; immune response;; immune system development;; leukocyte activation;; lymphocyte costimulation;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; positive regulation of metabolic process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; response to external stimulus;; response to stress;; somatic diversification of immune receptors;; T cell selection 17.8044 20.1361 18.3384 49.2846 28.3416 46.7672 248.9299 268.4852 653.5010 643.1115 246.2027 725.4607 255.1171 453.8417 590.9852 134.6512 73.0052 94.5830 1343687 1418507_s_at 10 C2|10 52.0 cM chr10:94874243-94874582 10 C2 UGA Mm.474283 216233 Socs2 Suppressor of cytokine signaling 2 (Socs2), mRNA Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 42.1646 37.8794 50.0380 57.8193 76.5623 68.3550 164.7075 175.9609 413.8376 349.4793 184.0654 397.5633 502.3105 462.2016 605.9685 176.4864 150.8865 189.4122 1330166 1418981_at 9 1.11 cM chr9:5354642-5371964 9 A1 chr9:5345475-5373034 9 A1 RSQ Mm.42163 NM_009808 2 2 12364 Casp12 caspase 12 (Casp12), mRNA. Alzheimer's disease;; Amyotrophic lateral sclerosis (ALS);; Apoptosis;; Prion diseases CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Human Diseases; Neurodegenerative Diseases; Alzheimer's disease [PATH:mmu05010] Human Diseases; Neurodegenerative Diseases; Amyotrophic lateral sclerosis (ALS) [PATH:mmu05014] Human Diseases; Neurodegenerative Diseases; Prion diseases [PATH:mmu05020] apoptosis;; apoptosis in response to endoplasmic reticulum stress;; cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; endoplasmic reticulum;; endoplasmic reticulum unfolded protein response;; hydrolase activity;; induction of apoptosis;; intracellular;; peptidase activity;; protein binding;; proteolysis;; regulation of apoptosis;; virus-infected cell apoptosis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; positive regulation of biological process;; regulation of biological process;; response to stimulus catabolic process;; cell communication;; cell death;; cellular response to stimulus;; macromolecule metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to biotic stimulus;; response to chemical stimulus;; response to stress 214.4234 228.9297 176.0408 297.3186 279.9465 252.4171 200.1609 167.7075 560.8443 521.5580 174.5408 507.9575 700.2908 558.4112 649.1553 224.4297 204.4297 214.4663 1344533 1422102_a_at 11 60.5 cM chr11:100644325-100648678 11 D chr11:100642044-100711899 11 D RSQ Mm.34064 NM_001113563 2 1 20851 RP23-279L23.3 Stat5b signal transducer and activator of transcription 5B (Stat5b), mRNA. Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] Human Diseases; Cancers; Pathways in cancer [PA;; Chemokine signaling pathway;; Chronic myeloid leukemia;; ErbB signaling pathway;; Jak-STAT signaling pathway;; Pathways in cancer calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; development of secondary female sexual characteristics;; development of secondary male sexual characteristics;; development of secondary male sexual characteristics;; DNA binding;; female pregnancy;; female pregnancy;; JAK-STAT cascade;; lactation;; lipid storage;; luteinization;; natural killer cell differentiation;; negative regulation of apoptosis;; negative regulation of erythrocyte differentiation;; nucleus;; Peyer's patch development;; positive regulation of activated T cell proliferation;; positive regulation of activated T cell proliferation;; positive regulation of B cell differentiation;; positive regulation of cell proliferation;; positive regulation of gamma-delta T cell differentiation;; positive regulation of inflammatory response;; positive regulation of interleukin-2 biosynthetic process;; positive regulation of lymphocyte differentiation;; positive regulation of mitotic cell cycle;; positive regulation of multicellular organism growth;; positive regulation of multicellular organism growth;; positive regulation of natural killer cell differentiation;; positive regulation of natural killer cell mediated cytotoxicity;; positive regulation of natural killer cell proliferation;; positive regulation of survival gene product expression;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; progesterone metabolic process;; protein binding;; regulation of cell adhesion;; regulation of epithelial cell differentiation;; regulation of steroid metabolic process;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; response to interleukin-15;; response to interleukin-2;; response to interleukin-4;; sex differentiation;; signal transducer activity;; signal transduction;; T cell differentiation in the thymus;; T cell homeostasis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription factor activity biological adhesion;; biological regulation;; cell killing;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus;; rhythmic process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell activation;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; female pregnancy;; hormone metabolic process;; immune effector process;; immune response;; immune system development;; leukocyte activation;; leukocyte homeostasis;; leukocyte mediated cytotoxicity;; macromolecule localization;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of growth;; positive regulation of immune system process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of homeostatic process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; response to chemical stimulus;; response to external stimulus;; response to stress 36.8179 32.6977 47.5826 137.0905 121.0724 106.5132 195.1879 183.1424 842.1944 887.5067 193.3896 963.3258 1420.4606 1362.1924 1505.7619 301.7720 176.5317 187.4154 1344534 1422103_a_at 11 60.5 cM chr11:100642207-100642625 11 D chr11:100642044-100711899 11 D RSQ Mm.34064 NM_001113563 2 1 20851 RP23-279L23.3 Stat5b signal transducer and activator of transcription 5B (Stat5b), mRNA. Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Immune System; Chemokine signaling pathway [PATH:mmu04062] Human Diseases; Cancers; Pathways in cancer [PA;; Chemokine signaling pathway;; Chronic myeloid leukemia;; ErbB signaling pathway;; Jak-STAT signaling pathway;; Pathways in cancer calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; development of secondary female sexual characteristics;; development of secondary male sexual characteristics;; development of secondary male sexual characteristics;; DNA binding;; female pregnancy;; female pregnancy;; JAK-STAT cascade;; lactation;; lipid storage;; luteinization;; natural killer cell differentiation;; negative regulation of apoptosis;; negative regulation of erythrocyte differentiation;; nucleus;; Peyer's patch development;; positive regulation of activated T cell proliferation;; positive regulation of activated T cell proliferation;; positive regulation of B cell differentiation;; positive regulation of cell proliferation;; positive regulation of gamma-delta T cell differentiation;; positive regulation of inflammatory response;; positive regulation of interleukin-2 biosynthetic process;; positive regulation of lymphocyte differentiation;; positive regulation of mitotic cell cycle;; positive regulation of multicellular organism growth;; positive regulation of multicellular organism growth;; positive regulation of natural killer cell differentiation;; positive regulation of natural killer cell mediated cytotoxicity;; positive regulation of natural killer cell proliferation;; positive regulation of survival gene product expression;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; progesterone metabolic process;; protein binding;; regulation of cell adhesion;; regulation of epithelial cell differentiation;; regulation of steroid metabolic process;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; response to interleukin-15;; response to interleukin-2;; response to interleukin-4;; sex differentiation;; signal transducer activity;; signal transduction;; T cell differentiation in the thymus;; T cell homeostasis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription factor activity biological adhesion;; biological regulation;; cell killing;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus;; rhythmic process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell activation;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; female pregnancy;; hormone metabolic process;; immune effector process;; immune response;; immune system development;; leukocyte activation;; leukocyte homeostasis;; leukocyte mediated cytotoxicity;; macromolecule localization;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of growth;; positive regulation of immune system process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of homeostatic process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; response to chemical stimulus;; response to external stimulus;; response to stress 48.3118 50.5877 59.0861 49.5796 80.8323 49.3861 67.1359 51.3696 489.9384 431.6515 47.0724 377.0922 555.6433 734.1229 760.2554 124.9346 74.9565 80.3294 1345143 1424795_a_at 2 chr2:30651685-30653425 2 B chr2:30651082-30657227 2 B RSQ Mm.34166 NM_198000 1 1 73598 RP23-221O14.1 1700001O22Rik RIKEN cDNA 1700001O22 gene (1700001O22Rik), mRNA. 16.7457 23.9955 18.2506 22.0354 22.0988 37.2792 92.0472 89.8266 191.7828 181.2917 85.0148 171.0661 178.8125 152.7356 192.1384 116.8197 74.4440 59.4200 1335963 1427167_at X E3 chrX:131230701-131230976 X E3 UGA Mm.31961 102910 Armcx4 Armadillo repeat containing, X-linked 4, mRNA (cDNA clone IMAGE:5374915) 74.1144 84.8762 61.9197 57.8193 82.1259 42.7128 361.9962 351.5033 591.9471 620.0180 368.9119 622.0585 359.7200 350.5555 411.1179 201.9090 174.3739 180.6281 1336101 1427339_at 4 D3 chr4:133909818-133910346 4 D3 UGA Mm.358876 230810 Slc30a2 Solute carrier family 30 (zinc transporter), member 2, mRNA (cDNA clone IMAGE:4239648) 2469.0588 1833.6796 2089.5172 5094.7275 4581.5947 5555.6635 758.9211 784.7345 1125.1624 1045.3071 789.7075 1049.0672 1682.9176 1113.2225 1816.3872 845.2527 743.7337 594.4004 1346063 1427364_a_at 12 6.0 cM chr12:17551678-17558308 12 A1.1 RSQ Mm.34102 NM_013614 1 1 18263 Odc1 ornithine decarboxylase, structural 1 (Odc1), mRNA. Arginine and proline metabolism;; Glutathione metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism [PATH:mmu00480] carboxy-lyase activity;; catalytic activity;; cytosol;; kidney development;; lyase activity;; ornithine decarboxylase activity;; polyamine biosynthetic process;; positive regulation of cell proliferation cell;; cell part cell part;; intracellular;; intracellular part catalytic activity lyase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell proliferation;; cellular metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 20.4691 19.6137 19.8437 20.8589 19.1393 20.3895 20.9009 20.5427 93.2300 94.2457 22.6625 122.9824 106.4931 42.3269 37.0779 16.8811 9.8637 23.7602 1336340 1427722_at 6 chr6:137932110-138021719 6 G1 RSQ Mm.269823 NM_177787 1 1 277898 Slc15a5 solute carrier family 15, member 5 (Slc15a5), mRNA. integral to membrane;; membrane;; oligopeptide transport;; peptide transport;; protein transport;; symporter activity;; transport;; transporter activity cell;; cell part cell part;; membrane;; membrane part transporter activity transmembrane transporter activity establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 84.1527 69.4702 94.8623 86.1372 56.1097 56.2483 141.9958 142.2075 170.4603 184.8394 155.6311 169.9445 200.7433 217.3496 222.2571 107.0690 87.7749 109.8771 1336547 1428031_at 15 chr15:81068086-81068498 15 E1 chr15:81066203-81068542 15 E1 RSQ Mm.323523 NM_145132 1 1 207911 Mchr1 melanin-concentrating hormone receptor 1 (Mchr1), mRNA. Neuroactive ligand-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Interaction; Neuroactive ligand-receptor interaction [PATH:mmu04080] G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; melanin-concentrating hormone receptor activity;; membrane;; neuropeptide signaling pathway;; nonmotile primary cilium;; plasma membrane;; receptor activity;; regulation of feeding behavior;; signal transducer activity;; signal transduction cell;; cell part cell part;; cell projection;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; regulation of biological process;; response to stimulus behavior;; cell communication;; regulation of biological process;; regulation of cellular process;; regulation of response to stimulus 6687.3671 6043.3741 5708.4380 6664.1734 7009.6519 8174.1733 1520.5682 1560.5462 1424.5334 1909.5881 1560.3095 1934.8143 1810.1088 1270.1519 2162.3660 1041.4852 824.2759 552.1519 1347648 1437711_x_at 12 6.0 cM chr12:17551678-17558308 12 A1.1 RSQ Mm.34102 NM_013614 3 3 18263 Odc1 ornithine decarboxylase, structural 1 (Odc1), mRNA. Arginine and proline metabolism;; Glutathione metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism [PATH:mmu00480] carboxy-lyase activity;; catalytic activity;; cytosol;; kidney development;; lyase activity;; ornithine decarboxylase activity;; polyamine biosynthetic process;; positive regulation of cell proliferation cell;; cell part cell part;; intracellular;; intracellular part catalytic activity lyase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell proliferation;; cellular metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 10735.8480 10602.4838 9343.8561 11600.0707 11040.1486 13638.8741 3180.6963 3246.2949 4260.7474 4387.6364 3321.6179 4521.6353 5555.4619 3957.2088 6576.0122 2995.5964 2816.5713 2034.2963 1347907 1438761_a_at 12 6.0 cM chr12:17557522-17557737 12 A1.1 chr12:17551678-17558308 12 A1.1 RSQ Mm.34102 NM_013614 5 5 18263 Odc1 ornithine decarboxylase, structural 1 (Odc1), mRNA. Arginine and proline metabolism;; Glutathione metabolism;; Metabolic pathways CLASS Metabolism; Amino Acid Metabolism; Arginine and proline metabolism [PATH:mmu00330] Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism [PATH:mmu00480] carboxy-lyase activity;; catalytic activity;; cytosol;; kidney development;; lyase activity;; ornithine decarboxylase activity;; polyamine biosynthetic process;; positive regulation of cell proliferation cell;; cell part cell part;; intracellular;; intracellular part catalytic activity lyase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell proliferation;; cellular metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 228.0238 398.3964 283.2197 495.2884 453.0797 551.0824 1230.2147 1169.5646 4293.6797 4113.7206 1136.2792 4409.4028 1080.4852 1721.8420 3238.0171 495.1049 180.4638 363.2432 1339177 1448724_at 9 59.0 cM chr9:107203813-107204254 9 F1 chr9:107199019-107204292 9 F1 RSQ Mm.4592 NM_009895 1 1 12700 Cish cytokine inducible SH2-containing protein (Cish), mRNA. Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; intracellular signaling cascade;; modification-dependent protein catabolic process;; negative regulation of signal transduction;; plasma membrane;; protein binding;; regulation of growth cell;; cell part cell part;; membrane binding protein binding biological regulation;; cellular process;; growth;; metabolic process;; negative regulation of biological process;; regulation of biological process catabolic process;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of growth;; regulation of metabolic process;; regulation of molecular function 38.4313 29.2628 32.6417 62.9996 52.0411 64.4851 472.4270 433.4186 1003.3441 981.8046 474.8078 934.7482 597.6048 845.6000 1011.9679 231.8657 185.9429 203.6540 1339494 1449109_at 10 52.0 cM chr10:94875126-94875560 10 C2 chr10:94874675-94879455 10 C2 RSQ Mm.474283 NM_007706 3 3 216233 Socs2 suppressor of cytokine signaling 2 (Socs2), mRNA. Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 24.8068 23.7843 23.5432 29.1122 27.2175 25.4449 101.0482 111.2058 258.5023 239.1447 98.5324 253.1287 298.3186 317.9297 362.7039 116.8754 77.1682 97.8343 1339649 1449297_at 9 1.11 cM chr9:5372098-5372617 9 A1 chr9:5345475-5373034 9 A1 RSQ Mm.42163 NM_009808 2 2 12364 Casp12 caspase 12 (Casp12), mRNA. Alzheimer's disease;; Amyotrophic lateral sclerosis (ALS);; Apoptosis;; Prion diseases CLASS Cellular Processes; Cell Growth and Death; Apoptosis [PATH:mmu04210] Human Diseases; Neurodegenerative Diseases; Alzheimer's disease [PATH:mmu05010] Human Diseases; Neurodegenerative Diseases; Amyotrophic lateral sclerosis (ALS) [PATH:mmu05014] Human Diseases; Neurodegenerative Diseases; Prion diseases [PATH:mmu05020] apoptosis;; apoptosis in response to endoplasmic reticulum stress;; cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; endoplasmic reticulum;; endoplasmic reticulum unfolded protein response;; hydrolase activity;; induction of apoptosis;; intracellular;; peptidase activity;; protein binding;; proteolysis;; regulation of apoptosis;; virus-infected cell apoptosis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding biological regulation;; cellular process;; death;; developmental process;; metabolic process;; positive regulation of biological process;; regulation of biological process;; response to stimulus catabolic process;; cell communication;; cell death;; cellular response to stimulus;; macromolecule metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to biotic stimulus;; response to chemical stimulus;; response to stress 292.3919 271.6886 245.1151 274.8274 326.9900 256.0853 233.8353 225.3646 345.6923 333.0883 222.1680 327.0964 465.5213 505.1972 626.4852 266.3712 204.3848 257.8708 1339803 1449483_at 13 chr13:97251181-97251607 13 D1 chr13:97250643-97312440 13 D1 RSQ Mm.89926 NM_012048 1 1 27015 Polk polymerase (DNA directed), kappa (Polk), mRNA. damaged DNA binding;; DNA binding;; DNA repair;; DNA replication;; DNA-directed DNA polymerase activity;; magnesium ion binding;; metal ion binding;; nucleotidyltransferase activity;; nucleus;; response to DNA damage stimulus;; transferase activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; transferase activity cellular process;; metabolic process;; response to stimulus biosynthetic process;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; nitrogen compound metabolic process;; primary metabolic process;; response to stress 13.8932 16.3582 22.5512 59.7969 39.8737 43.7828 25.8331 31.5116 82.9659 78.6861 31.5116 72.4687 166.3186 137.2517 149.8765 74.5429 65.4503 55.7989 1348627 1450259_a_at 11 60.5 cM chr11:100742343-100745240 11 D chr11:100720716-100746483 11 D RSQ Mm.277403 NM_011488 1 1 20850 RP23-279L23.4 Stat5a signal transducer and activator of transcription 5A (Stat5a), mRNA. EPO Signaling Pathway;; Growth Hormone Signaling Pathway;; IL 2 signaling pathway;; IL 3 signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; IL-7 Signal Transduction;; IL22 Soluble Receptor Signaling Pathway;; Inhibition of Cellular Proliferation by Gleevec;; TPO Signaling Pathway Acute myeloid leukemia CLASS Environmental Information Processing; Signal Transduction; ErbB signaling pathway [PATH:mmu04012] Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200] Human Diseases; Cancers; Acute myeloid leukemia [PATH:mmu05221] Hu;; Chronic myeloid leukemia;; ErbB signaling pathway;; Jak-STAT signaling pathway;; Pathways in cancer calcium ion binding;; cytokine-mediated signaling pathway;; cytoplasm;; development of secondary female sexual characteristics;; development of secondary male sexual characteristics;; development of secondary male sexual characteristics;; DNA binding;; epithelial cell differentiation involved in prostate gland development;; female pregnancy;; JAK-STAT cascade;; lactation;; lipid storage;; luteinization;; mammary gland development;; natural killer cell differentiation;; negative regulation of apoptosis;; negative regulation of erythrocyte differentiation;; negative regulation of mast cell apoptosis;; nucleus;; peptidyl-tyrosine phosphorylation;; Peyer's patch development;; positive regulation of activated T cell proliferation;; positive regulation of activated T cell proliferation;; positive regulation of B cell differentiation;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; positive regulation of gamma-delta T cell differentiation;; positive regulation of inflammatory response;; positive regulation of interleukin-2 biosynthetic process;; positive regulation of lymphocyte differentiation;; positive regulation of mast cell differentiation;; positive regulation of mast cell proliferation;; positive regulation of mitotic cell cycle;; positive regulation of multicellular organism growth;; positive regulation of natural killer cell differentiation;; positive regulation of natural killer cell mediated cytotoxicity;; positive regulation of survival gene product expression;; positive regulation of transcription from RNA polymerase II promoter;; positive regulation of transcription from RNA polymerase II promoter;; prostate gland epithelium morphogenesis;; protein binding;; regulation of cell adhesion;; regulation of epithelial cell differentiation;; regulation of steroid metabolic process;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; response to peptide hormone stimulus;; signal transducer activity;; signal transduction;; T cell differentiation in the thymus;; T cell homeostasis;; transcription;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; molecular transducer activity;; transcription regulator activity ion binding;; nucleic acid binding;; protein binding;; signal transducer activity;; transcription factor activity biological adhesion;; biological regulation;; cell killing;; cellular process;; death;; developmental process;; growth;; immune system process;; localization;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus;; rhythmic process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cell activation;; cell adhesion;; cell communication;; cell cycle;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; female pregnancy;; immune effector process;; immune response;; immune system development;; leukocyte activation;; leukocyte homeostasis;; leukocyte mediated cytotoxicity;; macromolecule localization;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; nitrogen compound metabolic process;; ovulation cycle;; ovulation cycle process;; positive regulation of biological process;; positive regulation of cell killing;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of growth;; positive regulation of immune system process;; positive regulation of metabolic process;; positive regulation of multicellular organismal process;; positive regulation of response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cell killing;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of homeostatic process;; regulation of immune system process;; regulation of metabolic process;; regulation of multicellular organismal process;; regulation of response to stimulus;; reproductive developmental process;; reproductive process;; reproductive process in a multicellular organism;; response to chemical stimulus;; response to endogenous stimulus;; response to external stimulus;; response to stress 55.6164 55.6164 58.3606 49.0425 52.2882 62.2736 351.4852 390.0426 1629.9509 1790.5964 342.2789 1860.1253 229.7631 276.4024 442.2075 129.3800 117.5628 98.9141 1341364 1451715_at 2 91.0 cM chr2:160191130-160191719 2 H2 chr2:160189412-160192801 2 H2 RSQ Mm.330745 NM_010658 1 1 16658 RP23-333A18.1 Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA. brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 104.7092 115.8596 130.8743 90.6181 117.8875 143.2256 715.7394 690.2579 2766.2138 2808.5714 665.3594 2755.7235 652.5212 666.6209 1120.3174 341.1308 278.8834 265.8186 1341365 1451716_at 2 H2|2 91.0 cM chr2:160189869-160190403 2 H2 UG5 Mm.330745 16658 RP23-333A18.1 Mafb V-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA brain segmentation;; DNA binding;; inner ear morphogenesis;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; respiratory gaseous exchange;; rhombomere 5 development;; rhombomere 6 development;; segment specification;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; nitrogen compound metabolic process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; respiratory gaseous exchange 19.7915 27.3467 17.8997 16.1982 17.9287 18.4070 161.5834 168.0249 324.3930 305.3578 180.7075 308.0631 558.7154 478.8456 747.4913 220.8808 192.5369 160.8191 1341594 1452106_at 3 chr3:132545193-132545281 3 G3 UGA Mm.440226 Transcribed locus 12.1140 15.0824 14.0361 14.9930 13.5626 12.1668 31.0002 34.1491 63.7421 59.9165 33.2156 59.6938 107.3401 76.1409 108.5822 32.5923 30.6299 34.2547 1349197 1452107_s_at 3 chr3:132544767-132545118 3 G3 UGA Mm.440226 Transcribed locus 15.9337 20.8409 19.6265 20.2143 18.3331 17.6289 22.4003 22.3235 28.8001 31.5855 19.9450 44.8858 43.8126 40.1095 45.7212 23.6600 19.1201 19.0474 1350458 1428387_at 1 24.1 cM chr1:78703742-78704161 1 C4 chr1:78654399-78704318 1 C4 RSQ Mm.276016 NM_001136222 3 1 74205 Acsl3 acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 3, mRNA. Adipocytokine signaling pathway CLASS Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:mmu00071] Environmental Information Processing; Membrane Transport; Other transporters Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320];; Fatty acid metabolism;; Metabolic pathways;; PPAR signaling pathway ATP binding;; catalytic activity;; endoplasmic reticulum;; fatty acid metabolic process;; integral to membrane;; ligase activity;; lipid metabolic process;; long-chain-fatty-acid-CoA ligase activity;; magnesium ion binding;; membrane;; metabolic process;; microsome;; mitochondrial outer membrane;; mitochondrion;; nucleotide binding;; peroxisome cell;; cell part;; envelope;; organelle;; organelle part cell fraction;; cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; catalytic activity ion binding;; ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process cellular metabolic process;; primary metabolic process 79.3460 65.0256 68.5228 95.1100 81.6388 78.1968 90.4863 80.8346 130.5659 120.6834 89.4227 111.2311 179.3990 163.5236 199.1235 104.1016 60.4963 86.7366 1352211 1430843_at 9 chr9:115915789-115983407 9 F3 chr9:115818572-115985294 9 F3 RSQ Mm.29221 NM_028638 1 1 73748 Gadl1 glutamate decarboxylase-like 1 (Gadl1), mRNA. carboxy-lyase activity;; carboxylic acid metabolic process;; catalytic activity;; lyase activity;; pyridoxal phosphate binding binding;; catalytic activity cofactor binding;; lipid binding;; lyase activity;; vitamin binding cellular process;; metabolic process cellular metabolic process 117.3344 65.6846 91.9802 59.1016 57.0308 54.3299 222.2389 264.1762 268.3589 294.0615 259.0106 344.8308 246.9030 184.4152 268.8305 125.0574 94.8466 100.3231 1354351 1433898_at 14 chr14:76160237-76160494 14 D3 UGA Mm.396080 Transcribed locus 43.1165 38.6592 45.2781 29.9397 41.5449 43.3398 30.9623 42.6913 94.6231 83.2493 44.5354 78.6205 128.8303 133.1761 157.9499 75.2886 49.8386 55.2788 1355746 1436309_at 8 chr8:88161038-88161540 8 C3 chr8:88160486-88214908 8 C3 RSQ Mm.126079 NM_001081324 1 1 74513 Neto2 neuropilin (NRP) and tolloid (TLL)-like 2 (Neto2), mRNA. integral to membrane;; membrane;; plasma membrane;; receptor activity cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity 36.4542 34.6507 23.9269 42.2096 32.5182 37.4998 88.5275 76.0028 188.1409 120.8790 82.3322 111.8483 73.7221 105.0405 115.4938 36.9443 33.9261 46.2234 1356918 1438470_at 10 C2|10 52.0 cM chr10:94850448-94851019 10 C2 UGA Mm.440128 216233 Socs2 Suppressor of cytokine signaling 2, mRNA (cDNA clone IMAGE:1068260) Insulin signaling pathway;; Jak-STAT signaling pathway;; Type II diabetes mellitus CLASS Environmental Information Processing; Signal Transduction; Jak-STAT signaling pathway [PATH:mmu04630] Cellular Processes; Endocrine System; Insulin signaling pathway [PATH:mmu04910] Human Diseases; Metabolic Disorders; Type II diabetes mellitus [PATH:mmu04930] growth hormone receptor binding;; intracellular signaling cascade;; lactation;; lactation;; mammary gland alveolus development;; mammary gland alveolus development;; modification-dependent protein catabolic process;; negative regulation of JAK-STAT cascade;; negative regulation of multicellular organism growth;; negative regulation of multicellular organism growth;; negative regulation of signal transduction;; positive regulation of neuron differentiation;; regulation of growth;; regulation of multicellular organism growth binding protein binding biological regulation;; cellular process;; developmental process;; growth;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; catabolic process;; cell communication;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organism growth;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; negative regulation of multicellular organismal process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of multicellular organismal process;; reproductive process;; reproductive process in a multicellular organism 254.6228 234.4385 205.0104 313.7068 256.9484 251.2402 178.5510 144.3592 266.8818 306.7982 184.2070 315.0408 252.3677 374.0326 453.9504 160.1131 175.2817 187.4064 1357769 1439844_at 15 chr15:81073316-81073676 15 E1 UGA Mm.296832 78102 8430426J06Rik CDNA clone IMAGE:3368992 49.2502 53.4814 51.5917 43.7548 43.0360 46.1209 114.4313 113.9699 304.5925 328.7047 113.0672 401.3536 458.4861 460.1643 620.7335 270.0419 105.7489 96.3556 1359154 1441384_at 9 F3 chr9:115984734-115985251 9 F3 UG5 Mm.29221 73748 Gadl1 Glutamate decarboxylase-like 1 (Gadl1), mRNA carboxy-lyase activity;; carboxylic acid metabolic process;; catalytic activity;; lyase activity;; pyridoxal phosphate binding binding;; catalytic activity cofactor binding;; lipid binding;; lyase activity;; vitamin binding cellular process;; metabolic process cellular metabolic process 50.9236 75.2505 59.7120 46.6197 65.4652 70.6477 66.3173 65.7148 135.2879 117.4626 77.2464 108.7614 35.0984 31.0789 44.2829 13.2299 21.4879 16.3409 1363875 1446509_at chr2:131342326-131342825 2 F1 IPA B130066H01Rik RIKEN cDNA B130066H01 gene 86.1739 64.0624 91.3430 102.6487 106.3951 105.2779 163.2630 149.6342 431.9551 370.4974 160.3225 367.5856 282.7366 290.2828 441.2631 145.0960 98.2182 99.2781 1372229 1452771_s_at 1 24.1 cM chr1:78703065-78703322 1 C4 chr1:78654399-78704318 1 C4 RSQ Mm.276016 NM_001136222 3 1 74205 Acsl3 acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 3, mRNA. Adipocytokine signaling pathway CLASS Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:mmu00071] Environmental Information Processing; Membrane Transport; Other transporters Cellular Processes; Endocrine System; Adipocytokine signaling pathway [PATH:mmu04920] Cellular Processes; Endocrine System; PPAR signaling pathway [PATH:mmu03320];; Fatty acid metabolism;; Metabolic pathways;; PPAR signaling pathway ATP binding;; catalytic activity;; endoplasmic reticulum;; fatty acid metabolic process;; integral to membrane;; ligase activity;; lipid metabolic process;; long-chain-fatty-acid-CoA ligase activity;; magnesium ion binding;; membrane;; metabolic process;; microsome;; mitochondrial outer membrane;; mitochondrion;; nucleotide binding;; peroxisome cell;; cell part;; envelope;; organelle;; organelle part cell fraction;; cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; catalytic activity ion binding;; ligase activity;; nucleoside binding;; nucleotide binding cellular process;; metabolic process cellular metabolic process;; primary metabolic process 18.4807 20.3811 22.2198 28.8419 17.5167 18.4864 56.6816 47.6452 379.9297 338.0776 57.2635 368.4297 68.6281 77.4844 179.4429 28.0236 16.7551 28.4394 1366492 1454768_at 12 chr12:17179290-17179470 12 A1.1 chr12:17178905-17183694 12 A1.1 RSQ Mm.40173 NM_201531 1 1 382571 Kcnf1 potassium voltage-gated channel, subfamily F, member 1 (Kcnf1), mRNA. integral to membrane;; ion channel activity;; ion transport;; membrane;; potassium channel activity;; potassium ion binding;; potassium ion transport;; protein binding;; transport;; voltage-gated ion channel activity;; voltage-gated potassium channel activity;; voltage-gated potassium channel complex cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 29.4400 21.9108 29.1606 30.2491 29.6021 22.3630 660.4493 581.2630 1215.7705 1152.0391 613.9852 1120.9556 885.6439 1075.1794 895.1835 502.6790 403.8789 377.2622 1367020 1455647_at X chrX:95517594-95518094 X C3 UGA Mm.39005 Transcribed locus 170.5508 199.1926 124.1036 156.1014 132.5101 153.5051 124.3757 139.9304 166.0027 143.3408 128.7360 143.8669 354.7032 306.4024 354.5955 218.0023 159.4280 114.2602 1372388 1455966_s_at 8 chr8:96541804-96542041 8 C5 UGA Mm.432689 Transcribed locus 67.4383 71.8530 68.2470 75.3261 71.5535 54.9563 42.0233 40.3867 118.1431 94.5930 38.2933 80.9575 69.7181 70.0735 92.0686 34.4037 28.8514 51.9150 1368912 1458210_at 17 E1.1 chr17:66904670-66905148 17 E1.1 UG5 Mm.218634 74556 9130404H23Rik PREDICTED: Mus musculus RIKEN cDNA 9130404H23 gene (9130404H23Rik), mRNA