A 1 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen A 2 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen A 3 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen B 4 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen B 5 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen B 6 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen The input data set contained 45101 genes The filtered output data set contains 226 genes 40673 gene rows removed by Include where <b>A-B T-test p-value (two tailed)</b> <= 0.05 4202 gene rows removed by Include where <b>A-B Mean Difference</b> >= 1.0 A A A B B B 06-08-04_Hennighausen_Mouse430_2_KO1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_KO3 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT1 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT2 GSP-EG001 Hennighausen 06-08-04_Hennighausen_Mouse430_2_WT3 GSP-EG001 Hennighausen A-B p-Value A-B Mean Difference A Mean B Mean Well ID Feature ID mgB36 Chr:Start-Stop mgB36 Cytoband Annotation_Src UniGene RefSeq Refseqs_Hit geneIDS_Hit Entrez GeneID Locus Tag Gene Description BioCarta Pathways KEGG Pathways Gene Ontology Terms GO Tier2 Component GO Tier3 Component GO Tier2 Function GO Tier3 Function GO Tier2 Process GO Tier3 Process 782.0236 569.3006 605.2431 302.9594 226.6000 260.3770 0.0021427204 1.30468 9.33516 8.03048 1327572 1415761_at chr14:53381113-53383955 14 C2 RSQ Mm.248163 NM_026851 1 1 68836 Mrpl52 mitochondrial ribosomal protein L52 (Mrpl52), nuclear gene encoding mitochondrial protein, mRNA. mitochondrion;; ribonucleoprotein complex;; ribosome cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; ribonucleoprotein complex 888.2271 689.7763 881.8870 436.4445 336.4756 371.4308 0.0024507357 1.10275 9.66974 8.56699 1343142 1415762_x_at chr14:53381113-53383955 14 C2 RSQ Mm.248163 NM_026851 1 1 68836 Mrpl52 mitochondrial ribosomal protein L52 (Mrpl52), nuclear gene encoding mitochondrial protein, mRNA. mitochondrion;; ribonucleoprotein complex;; ribosome cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; ribonucleoprotein complex 169.0987 139.4248 204.2256 59.4762 57.5729 100.1214 0.013856543 1.27064 7.39970 6.12906 1327623 1415826_at chr1:5073253-5152630 1 A1 RSQ Mm.27082 NM_133826 1 1 108664 Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H (Atp6v1h), mRNA. Oxidative phosphorylation CLASS Metabolism; Energy Metabolism; Oxidative phosphorylation [PATH:m ATP synthesis coupled proton transport;; binding;; hydrogen ion transmembrane transporter activity;; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;; ion transport;; proton transport;; proton-transporting ATPase activity, rotational mechanism;; transport;; vacuolar proton-transporting V-type ATPase, V1 domain cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part;; protein complex binding;; catalytic activity;; transporter activity hydrolase activity;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; primary metabolic process;; transmembrane transport;; transport 3709.2182 3821.2838 4269.7806 2235.5076 1428.1046 2004.6698 0.0061274629 1.08042 11.93890 10.85847 1327671 1415888_at chr3:87992292-88002053 3 F1 RSQ Mm.292208 NM_008231 1 1 15191 Hdgf hepatoma-derived growth factor (Hdgf), mRNA. cellular process;; cytoplasm;; DNA binding;; extracellular space;; growth factor activity;; heparin binding;; nucleotide binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; extracellular region;; extracellular region part;; organelle cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding carbohydrate binding;; nucleic acid binding;; nucleotide binding;; pattern binding;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 120.5199 115.2653 236.6029 56.0304 49.5508 70.1825 0.020688787 1.35875 7.21609 5.85734 1327679 1415899_at chr8:87867089-87867599 8 C3 UGA Mm.1167 16477 Junb Jun-B oncogene GATA3 participate in activating the Th2 cytokine genes expression cellular process;; decidualization;; DNA binding;; embryonic placenta development;; embryonic process involved in female pregnancy;; in utero embryonic development;; nucleus;; positive regulation of cell differentiation;; protein dimerization activity;; regulation of cell cycle;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; trophectodermal cell differentiation;; trophectodermal cell differentiation;; vasculogenesis cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multi-organism process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation;; anatomical structure morphogenesis;; biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; embryonic development;; female pregnancy;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; reproductive process in a multicellular organism 1735.9014 1353.8455 1853.4356 948.9224 549.4689 1020.2930 0.032207178 1.01116 10.67343 9.66227 1327860 1416146_at chr11:53103236-53143902 11 B1.3 RSQ Mm.239865 NM_008300 1 1 15525 RP23-337J7.3 Hspa4 heat shock protein 4 (Hspa4), mRNA. Antigen processing and presentation CLASS Environmental Information Processing; Membrane Transpo ATP binding;; cytoplasm;; nucleotide binding;; response to stress cell;; cell part cell part;; intracellular;; intracellular part binding nucleotide binding response to stimulus response to stress 7853.3426 8132.7723 5532.4143 980.9644 1210.5735 1503.9655 0.00053728728 2.54274 12.78744 10.24470 1327904 1416203_at chr6:55265876-55278133 6 B3 RSQ Mm.18625 NM_007472 1 1 11826 Aqp1 aquaporin 1 (Aqp1), mRNA. integral to membrane;; integral to plasma membrane;; membrane;; transport;; transporter activity;; water channel activity;; water transport cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 115.5978 112.5790 103.1344 59.7085 47.7429 41.4001 0.0019362448 1.16917 6.78538 5.61621 1327953 1416263_at chr5:124322474-124356416 5 F RSQ Mm.254839 NM_019875 1 1 56325 Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 (Abcb9), mRNA. ABC transporters CLASS Environmental Information Processing; Membrane Transport; ABC transporter ATP binding;; ATPase activity;; ATPase activity, coupled to transmembrane movement of substances;; endoplasmic reticulum;; endoplasmic reticulum membrane;; integral to membrane;; lysosome;; membrane;; nucleoside-triphosphatase activity;; nucleotide binding;; oligopeptide transport;; oligopeptide transporter activity;; peptide transport;; peptide transporter activity;; protein transport;; transport cell;; cell part;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle membrane;; organelle part binding;; catalytic activity;; transporter activity hydrolase activity;; nucleotide binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 674.9892 573.7309 653.2307 303.2399 273.9867 292.0753 0.00017316494 1.12731 9.30480 8.17749 1328075 1416424_at chr17:55912670-55924220 17 D RSQ Mm.311696 NM_025836 1 1 66905 M6prbp1 mannose-6-phosphate receptor binding protein 1 (M6prbp1), mRNA. cytoplasm;; endosome;; lipid particle;; membrane;; transport cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle establishment of localization;; localization establishment of localization;; transport 467.8952 871.8704 762.0659 269.8407 227.6608 345.4641 0.01632612 1.29090 9.40393 8.11303 1328090 1416442_at chr8:87549655-87552953 8 C3 RSQ Mm.399 NM_010499 1 1 15936 Ier2 immediate early response 2 (Ier2), mRNA. cytoplasm cell;; cell part cell part;; intracellular;; intracellular part 1646.7152 932.4118 1051.1440 653.0309 462.8389 624.0275 0.024729466 1.03237 10.19598 9.16361 1328097 1416452_at chr7:132395817-132414741 7 F3 RSQ Mm.13694 NM_016978 1 1 18242 Oat ornithine aminotransferase (Oat), nuclear gene encoding mitochondrial protein, mRNA. Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline Arginine and proline metabolism CLASS Metabolism; Amino Acid Metabolism; Arginine and proline me catalytic activity;; mitochondrion;; ornithine-oxo-acid transaminase activity;; pyridoxal phosphate binding;; transaminase activity;; transferase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity cofactor binding;; lipid binding;; transferase activity;; vitamin binding 1890.7545 1119.2103 1309.2161 665.3636 575.0434 767.9386 0.01326495 1.07904 10.45583 9.37679 1328220 1416614_at chr2:125364540-125367084 2 F1 RSQ Mm.425101 NM_025613 1 1 58521 RP23-323D9.2 Eid1 EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA. cell cycle;; cell differentiation;; cytoplasm;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; specific transcriptional repressor activity;; transcription;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1221.5424 1299.2451 1967.4963 549.8210 565.7296 792.4015 0.011245775 1.22107 10.51336 9.29229 1328256 1416656_at chr17:34658298-34666775 17 B1 RSQ Mm.29524 NM_033444 1 1 114584 Clic1 chloride intracellular channel 1 (Clic1), mRNA. chloride channel activity;; chloride ion binding;; chloride transport;; cytoplasm;; ion channel activity;; ion transport;; membrane;; nuclear envelope;; nucleus;; protein binding;; transport;; voltage-gated chloride channel activity;; voltage-gated ion channel activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle envelope;; organelle part binding;; transporter activity ion binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 522.5421 646.3943 620.7114 151.0695 163.4913 158.1085 4.3251631e-05 1.91551 9.21448 7.29897 1328325 1416740_at chr2:27708693-27859533 2 A3 RSQ Mm.7281 NM_015734 1 1 12831 Col5a1 collagen, type V, alpha 1 (Col5a1), mRNA. ECM-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Int;; Focal adhesion basement membrane;; blood vessel development;; cell adhesion;; collagen;; collagen;; collagen fibril organization;; collagen fibril organization;; extracellular matrix;; extracellular matrix structural constituent;; extracellular region;; heart morphogenesis;; heparin binding;; platelet-derived growth factor binding;; protein binding;; proteinaceous extracellular matrix;; regulation of cellular component organization;; skin development;; structural molecule activity extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part binding;; structural molecule activity carbohydrate binding;; extracellular matrix structural constituent;; pattern binding;; protein binding biological adhesion;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component organization;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 500.5265 645.8852 396.8475 264.2086 198.3414 248.1489 0.0099329834 1.10081 8.97829 7.87748 1328326 1416741_at chr2:27860146-27860570 2 A3 RSQ Mm.7281 NM_015734 1 1 12831 Col5a1 collagen, type V, alpha 1 (Col5a1), mRNA. ECM-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Int;; Focal adhesion basement membrane;; blood vessel development;; cell adhesion;; collagen;; collagen;; collagen fibril organization;; collagen fibril organization;; extracellular matrix;; extracellular matrix structural constituent;; extracellular region;; heart morphogenesis;; heparin binding;; platelet-derived growth factor binding;; protein binding;; proteinaceous extracellular matrix;; regulation of cellular component organization;; skin development;; structural molecule activity extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part binding;; structural molecule activity carbohydrate binding;; extracellular matrix structural constituent;; pattern binding;; protein binding biological adhesion;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component organization;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 2617.4305 3362.1082 4486.6143 1563.8517 1182.4898 1560.9958 0.0085888692 1.25792 11.73350 10.47558 1343404 1416921_x_at chr7:126586383-126590331 7 F3 RSQ Mm.275831 NM_007438 1 1 11674 Aldoa aldolase A, fructose-bisphosphate (Aldoa), mRNA. Fructose and mannose metabolism CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeo;; Glycolysis / Gluconeogenesis;; Pentose phosphate pathway catalytic activity;; flagellum;; fructose-bisphosphate aldolase activity;; glycolysis;; lyase activity;; metabolic process cell;; cell part cell part;; cell projection catalytic activity lyase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 342.6642 372.5890 463.4765 103.0347 124.9855 139.8314 0.00077972134 1.67943 8.60615 6.92672 1328472 1416926_at chr4:11083587-11101524 4 A1 RSQ Mm.393018 NM_021897 1 1 60599 RP23-343F17.4 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Trp53inp1), mRNA. apoptosis;; cell cycle arrest;; cytoplasm;; induction of apoptosis;; nucleolus;; nucleus;; response to stress cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part biological regulation;; cellular process;; developmental process;; positive regulation of biological process;; regulation of biological process;; response to stimulus cell cycle;; cell cycle process;; cell death;; death;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to stress 207.6115 156.6127 231.4560 81.2170 82.5091 74.3296 0.0016996492 1.30578 7.61446 6.30869 1328557 1417027_at chr3:84246371-84306788 3 F1 UGA Mm.44876 80890 Trim2 Tripartite motif-containing 2 cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding 77.0194 54.8510 68.4318 30.6302 36.4129 30.6765 0.0034541678 1.02629 6.04706 5.02077 1343424 1417029_a_at chr3:84246371-84306788 3 F1 RSQ Mm.44876 NM_030706 1 1 80890 Trim2 tripartite motif-containing 2 (Trim2), mRNA. cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding 5059.0395 3884.1147 3970.9979 1315.6454 647.8805 415.6065 0.0065329003 2.59436 12.06110 9.46674 1343489 1417393_a_at chr4:154806117-154810429 4 E2 RSQ Mm.29140 NM_026125 1 1 67389 RP23-118E21.2 C1qdc2 C1q domain containing 2 (C1qdc2), mRNA. extracellular region extracellular region 2497.7518 2189.6064 3339.7345 1072.2278 1099.3057 1343.0656 0.0047565141 1.17610 11.36280 10.18670 1329049 1417620_at chr15:78386423-78400038 15 E1 RSQ Mm.1972 NM_009008 1 1 19354 Rac2 RAS-related C3 botulinum substrate 2 (Rac2), mRNA. Adherens junction;; Axon guidance;; B cell receptor signaling pathway;; Colorectal cancer;; Fc epsilon RI signaling pathway;; Focal adhesion;; Leukocyte transendothelial migration;; MAPK signaling pathway;; Natural killer cell mediated cytotoxicity;; Pancreatic cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signalin;; Regulation of actin cytoskeleton;; VEGF signaling pathway;; Wnt signaling pathway actin cytoskeleton organization;; cell projection assembly;; chemotaxis;; cytoplasm;; GTP binding;; GTPase activity;; intracellular;; membrane;; membrane fraction;; nuclear envelope;; nucleotide binding;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; small GTPase mediated signal transduction cell;; cell part;; envelope;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle envelope;; organelle part binding;; catalytic activity hydrolase activity;; nucleotide binding biological regulation;; cellular process;; developmental process;; locomotion;; positive regulation of biological process;; regulation of biological process;; response to stimulus actin filament-based process;; anatomical structure development;; anatomical structure morphogenesis;; behavior;; cell communication;; cell proliferation;; cellular component organization;; cellular developmental process;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; response to chemical stimulus;; response to external stimulus;; taxis 367.2956 162.7912 358.5616 100.9972 103.6776 157.6278 0.048120188 1.23308 8.11792 6.88484 1329114 1417707_at chr5:150840022-150862879 5 G3 RSQ Mm.279932 NM_133898 1 1 100637 N4bp2l1 NEDD4 binding protein 2-like 1 (N4bp2l1), mRNA. 773.3933 781.6104 704.7027 433.7010 295.7577 399.5345 0.0042929091 1.01841 9.55541 8.53700 1329554 1418231_at chr10:57718903-57820046 10 B4 RSQ Mm.57734 NM_026148 1 1 110829 Lims1 LIM and senescent cell antigen-like domains 1 (Lims1), mRNA. cell junction;; cell-cell adhesion;; cell-matrix adhesion;; chordate embryonic development;; establishment or maintenance of cell polarity;; focal adhesion;; membrane;; metal ion binding;; plasma membrane;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding ion binding;; protein binding biological adhesion;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component organization;; cellular developmental process;; embryonic development;; establishment or maintenance of cell polarity;; multicellular organismal development 5023.5157 4320.9903 3844.7520 2056.5111 1921.8765 2355.0639 0.0017106599 1.05482 12.09343 11.03861 1343630 1418232_s_at chr10:57718903-57820046 10 B4 RSQ Mm.57734 NM_026148 1 1 110829 Lims1 LIM and senescent cell antigen-like domains 1 (Lims1), mRNA. cell junction;; cell-cell adhesion;; cell-matrix adhesion;; chordate embryonic development;; establishment or maintenance of cell polarity;; focal adhesion;; membrane;; metal ion binding;; plasma membrane;; protein binding;; zinc ion binding cell;; cell part cell part;; membrane;; membrane part binding ion binding;; protein binding biological adhesion;; cellular process;; developmental process;; multicellular organismal process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component organization;; cellular developmental process;; embryonic development;; establishment or maintenance of cell polarity;; multicellular organismal development 168.3916 142.6748 171.2714 81.5397 53.6670 77.9959 0.0045997431 1.19723 7.32413 6.12691 1329593 1418288_at chr12:16561579-16562012 12 A1.1 UGA Mm.153625 14245 Lpin1 Lipin 1 actin cytoskeleton reorganization;; cellular response to insulin stimulus;; lipid metabolic process;; nucleus;; phosphatidate phosphatase activity;; regulation of fat cell differentiation;; ruffle organization cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; anatomical structure development;; anatomical structure morphogenesis;; cellular component organization;; cellular developmental process;; cellular response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to chemical stimulus;; response to endogenous stimulus 1812.1792 1461.4814 1580.8943 732.3338 452.6657 497.9593 0.002526543 1.55490 10.65442 9.09951 1329631 1418337_at chr6:70695298-70721754 6 C1 RSQ Mm.17905 NM_009075 1 1 19895 Rpia ribose 5-phosphate isomerase A (Rpia), mRNA. Pentose phosphate pathway CLASS Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway [ isomerase activity;; pentose-phosphate shunt, non-oxidative branch;; ribose-5-phosphate isomerase activity catalytic activity isomerase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 548.0036 212.1409 321.3084 77.3746 63.2653 110.6916 0.011567129 2.03573 8.38491 6.34918 1329767 1418497_at chrX:55408928-55481220 X A6 RSQ Mm.7995 NM_010200 1 1 14168 RP23-387L21.1 Fgf13 fibroblast growth factor 13 (Fgf13), mRNA. MAPK signaling pathway;; Melanoma CLASS Environmental Information Processing; Signal Transduction; MAPK signaling pathway;; Regulation of actin cytoskeleton cytoplasm;; growth factor activity;; MAPKKK cascade;; nucleus;; protein binding;; protein kinase activator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; enzyme regulator activity enzyme activator activity;; kinase regulator activity;; protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 745.9559 643.9299 899.6021 441.2211 222.3306 462.6860 0.042528956 1.08368 9.56228 8.47860 1330235 1419068_at chr5:130498468-130498868 5 G1.3 UG5 Mm.288639 56715 Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 cytoplasm;; DNA binding;; endocytosis;; endosome;; metal ion binding;; protein transport;; transport;; ubiquitin-dependent protein catabolic process;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding cellular process;; establishment of localization;; localization;; metabolic process catabolic process;; cellular component organization;; cellular metabolic process;; establishment of localization;; establishment of protein localization;; macromolecule localization;; macromolecule metabolic process;; primary metabolic process;; transport;; vesicle-mediated transport 2588.0262 2723.4375 2931.8871 1358.8785 989.9253 1414.2511 0.0025689428 1.14709 11.42215 10.27507 1343832 1419291_x_at chr1:162872436-162874936 1 H2.1 UGA Mm.270065 14455 Gas5 Growth arrest specific 5 1149.1602 1215.9644 1325.8670 740.3838 457.7574 515.8123 0.0063768947 1.13523 10.26232 9.12709 1330500 1419402_at chr9:72237101-72257141 9 D RSQ Mm.387671 NM_008613 1 1 17427 Mns1 meiosis-specific nuclear structural protein 1 (Mns1), mRNA. intermediate filament;; meiosis;; nuclear envelope;; nucleus cell;; cell part;; envelope;; organelle;; organelle part cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle envelope;; organelle part cellular process cell cycle;; cell cycle process 222.1621 183.0885 206.5523 77.9701 65.4932 148.0493 0.034298545 1.15806 7.66741 6.50935 1330636 1419574_at chr4:34991996-35071836 4 A5 RSQ Mm.38193 NM_013889 1 1 30046 RP24-349L5.1 Zfp292 zinc finger protein 292 (Zfp292), mRNA. 224.8503 206.4427 230.5867 107.4906 69.9447 164.2926 0.044416716 1.03842 7.78386 6.74544 1343891 1419575_s_at chr4:34991996-35071836 4 A5 RSQ Mm.38193 NM_013889 1 1 30046 RP24-349L5.1 Zfp292 zinc finger protein 292 (Zfp292), mRNA. 60.3473 52.2260 76.8801 32.9230 26.4108 31.4005 0.0051664547 1.04988 5.96215 4.91227 1330701 1419656_at chr9:96886362-96920393 9 E3.3 RSQ Mm.228067 NM_138756 1 1 192287 Slc25a36 solute carrier family 25, member 36 (Slc25a36), mRNA. binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrial transport;; mitochondrion;; transport;; transporter activity cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; transporter activity cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; transport 330.8554 299.5531 439.0561 130.3461 138.0512 212.3333 0.013418972 1.16985 8.45833 7.28848 1343908 1419657_a_at chr9:96884953-96885147 9 E3.3 UGA Mm.475433 Transcribed locus 167.4957 184.7387 207.8357 80.8714 73.4611 50.9229 0.002713129 1.46997 7.53887 6.06890 1343984 1419978_s_at chr10:126585477-126592968 10 D3 RSQ Mm.272230 NM_028027 1 1 52666 D10Ertd610e DNA segment, Chr 10, ERATO Doi 610, expressed (D10Ertd610e), mRNA. cytoplasm;; guanyl-nucleotide exchange factor activity;; intracellular;; intracellular signaling cascade;; regulation of Rho protein signal transduction;; Rho guanyl-nucleotide exchange factor activity cell;; cell part cell part;; intracellular;; intracellular part enzyme regulator activity GTPase regulator activity biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 556.8865 483.8638 511.6893 214.6252 169.8963 298.3301 0.0073401623 1.22129 9.01294 7.79165 1331326 1420640_at chr13:94534954-94600442 13 C3 RSQ Mm.390630 NM_021310 1 1 57748 Jmy junction-mediating and regulatory protein (Jmy), mRNA. actin binding;; actin cytoskeleton;; cell adhesion;; DNA repair;; induction of apoptosis;; nucleus;; protein binding;; regulation of transcription from RNA polymerase II promoter;; response to DNA damage stimulus;; structural molecule activity;; transcription coactivator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle binding;; structural molecule activity;; transcription regulator activity protein binding;; transcription activator activity;; transcription cofactor activity biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; positive regulation of biological process;; regulation of biological process;; response to stimulus biosynthetic process;; cell adhesion;; cell death;; cellular metabolic process;; cellular response to stimulus;; death;; macromolecule metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; response to stress 973.4125 867.0393 1027.0958 416.4405 310.9377 379.8845 0.00065969687 1.37978 9.89707 8.51729 1331572 1420970_at chr8:91162507-91219135 8 C3 UGA Mm.288206 11513 Adcy7 Adenylate cyclase 7 Calcium signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environ;; Purine metabolism activation of adenylate cyclase activity;; adenylate cyclase activity;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 1804.1730 1849.3646 2834.5863 1189.7382 856.5706 1107.2930 0.016183964 1.02239 11.04629 10.02389 1344217 1420997_a_at chr7:33910917-33939017 7 B1 RSQ Mm.589 NM_008155 4 4 14751 RP23-349I9.4 Gpi1 glucose phosphate isomerase 1 (Gpi1), mRNA. Glycolysis / Gluconeogenesis;; Pentose phosphate pathway;; Starch and sucrose metabolism CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeoge cytokine activity;; cytoplasm;; extracellular space;; gluconeogenesis;; glucose metabolic process;; glucose-6-phosphate isomerase activity;; glucose-6-phosphate isomerase activity;; glycolysis;; growth factor activity;; isomerase activity;; protein binding cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular part binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process biosynthetic process;; catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 321.2864 301.6398 360.9233 161.6526 125.6052 119.6643 0.0011472425 1.28253 8.35332 7.07079 1331658 1421088_at chrX:48297338-48409879 X A5 RSQ Mm.1528 NM_008150 1 1 14735 Gpc4 glypican 4 (Gpc4), mRNA. anchored to membrane;; extracellular region;; membrane;; plasma membrane;; proteinaceous extracellular matrix cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular matrix;; extracellular region part;; membrane;; membrane part 333.6806 306.5723 510.8730 180.9224 173.0964 173.2130 0.008914102 1.08939 8.54641 7.45702 1344300 1421267_a_at chr10:17412661-17415072 10 A2 RSQ Mm.272321 NM_010828 1 1 17684 Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (Cited2), mRNA. adrenal gland development;; anti-apoptosis;; blood vessel development;; central nervous system development;; decidualization;; determination of left/right symmetry;; embryonic placenta development;; embryonic process involved in female pregnancy;; heart development;; heart development;; in utero embryonic development;; liver development;; nuclear chromatin;; nucleus;; positive regulation of cell cycle;; positive regulation of cell-cell adhesion;; positive regulation of specific transcription from RNA polymerase II promoter;; positive regulation of transcription, DNA-dependent;; positive regulation of transforming growth factor beta receptor signaling pathway;; protein binding;; regulation of transcription;; regulation of transcription from RNA polymerase II promoter;; regulation of transcription, DNA-dependent;; transcription;; transcription coactivator activity;; transcription cofactor activity;; transcription factor activity;; transcription regulator activity;; trophectodermal cell differentiation;; vasculogenesis cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription activator activity;; transcription cofactor activity;; transcription factor activity biological adhesion;; biological regulation;; cellular process;; developmental process;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure formation;; anatomical structure morphogenesis;; biosynthetic process;; cell adhesion;; cell communication;; cell cycle;; cell death;; cellular developmental process;; cellular metabolic process;; death;; embryonic development;; female pregnancy;; macromolecule metabolic process;; multicellular organism reproduction;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; pattern specification process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; reproductive process;; reproductive process in a multicellular organism 999.6002 720.6886 706.4003 351.3546 214.4659 273.4798 0.004164153 1.54203 9.64093 8.09889 1331784 1421268_at chr4:59312562-59314573 4 B3 UG5 Mm.198803 22234 RP23-57N22.4 Ugcg UDP-glucose ceramide glucosyltransferase Glycan structures - biosynthesis 2 CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [;; Sphingolipid metabolism ceramide glucosyltransferase activity;; endoplasmic reticulum;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity 367.6675 261.5801 259.2004 157.6737 144.0775 129.7957 0.0051314525 1.02656 8.19043 7.16387 1331785 1421269_at chr4:59283603-59316887 4 B3 RSQ Mm.198803 NM_011673 1 1 22234 RP23-57N22.4 Ugcg UDP-glucose ceramide glucosyltransferase (Ugcg), mRNA. Glycan structures - biosynthesis 2 CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [;; Sphingolipid metabolism ceramide glucosyltransferase activity;; endoplasmic reticulum;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity 1646.4609 997.4983 914.9923 367.1741 291.0973 202.3155 0.0049765189 2.03960 10.16165 8.12205 1344316 1421317_x_at chr10:20814345-20850400 10 A3 RSQ Mm.52109 NM_010848 1 1 17863 Myb myeloblastosis oncogene (Myb), mRNA. calcium ion transport;; DNA binding;; embryonic gut development;; G1/S transition of mitotic cell cycle;; in utero embryonic development;; nucleus;; protein binding;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell cycle;; cell cycle process;; cellular metabolic process;; embryonic development;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 178.4129 155.7141 137.3499 90.2664 57.0994 59.4569 0.0069663001 1.21275 7.28785 6.07510 1344354 1421457_a_at chr16:75741473-75791946 16 C3.1 RSQ Mm.131406 NM_023380 1 1 67742 Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 (Samsn1), mRNA. cytoplasm;; phosphotyrosine binding cell;; cell part cell part;; intracellular;; intracellular part binding protein binding 236.3666 288.9626 290.4808 70.9486 84.5820 62.1981 0.00029228909 1.91071 8.08064 6.16993 1332272 1421936_at chr3:137868392-137918936 3 G3 RSQ Mm.254835 NM_011932 1 1 26377 Dapp1 dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (Dapp1), mRNA. cytoplasm;; membrane;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; protein binding cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; protein binding 536.0002 426.6080 426.8895 140.3038 164.8038 209.5677 0.001979078 1.44410 8.84686 7.40276 1332273 1421937_at chr3:137868392-137918936 3 G3 RSQ Mm.254835 NM_011932 1 1 26377 Dapp1 dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (Dapp1), mRNA. cytoplasm;; membrane;; phosphoinositide 3-kinase complex;; phosphoinositide 3-kinase regulator activity;; protein binding cell;; cell part;; macromolecular complex cell part;; intracellular;; intracellular part;; membrane;; protein complex binding;; enzyme regulator activity kinase regulator activity;; protein binding 1185.4292 1138.0854 1380.6424 581.6229 367.5947 469.1082 0.002558562 1.40501 10.26490 8.85990 1332316 1422007_at chr4:41281394-41286854 4 A5 RSQ Mm.34043 NM_016689 1 1 11828 RP23-28I8.7 Aqp3 aquaporin 3 (Aqp3), mRNA. basolateral plasma membrane;; integral to membrane;; integral to plasma membrane;; membrane;; transport;; transporter activity;; water channel activity;; water transport cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 61.4109 41.0437 68.7835 17.5207 12.9828 15.5236 0.0019299784 1.87253 5.80117 3.92864 1344508 1422008_a_at chr4:41281852-41281926 4 A5 UGA Mm.34043 11828 RP23-28I8.7 Aqp3 Aquaporin 3 basolateral plasma membrane;; integral to membrane;; integral to plasma membrane;; membrane;; transport;; transporter activity;; water channel activity;; water transport cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 278.0406 199.3530 140.6509 47.3006 38.3551 35.9688 0.0017161325 2.30017 7.63144 5.33127 1344693 1422734_a_at chr10:20814345-20850400 10 A3 RSQ Mm.52109 NM_010848 1 1 17863 Myb myeloblastosis oncogene (Myb), mRNA. calcium ion transport;; DNA binding;; embryonic gut development;; G1/S transition of mitotic cell cycle;; in utero embryonic development;; nucleus;; protein binding;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell cycle;; cell cycle process;; cellular metabolic process;; embryonic development;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 435.0230 394.5181 767.1023 158.3161 171.9679 256.4218 0.018524787 1.41238 8.99072 7.57835 1333142 1423100_at chr12:86363003-86366372 12 D2 RSQ Mm.246513 NM_010234 1 1 14281 Fos FBJ osteosarcoma oncogene (Fos), mRNA. B Cell Survival Pathway;; BCR Signaling Pathway;; Cadmium induces DNA synthesis and proliferation in macrophages;; EGF Signaling Pathway;; EPO Signaling Pathway;; Fc Epsilon Receptor I Signaling in Mast Cells;; IGF-1 Signaling Pathway;; IL 2 signaling pathway;; IL 3 signaling pathway;; IL 6 signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; Inhibition of Cellular Proliferation by Gleevec;; Insulin Signaling Pathway;; MAPKinase Signaling Pathway;; METS affect on Macrophage Differentiation;; Nerve growth factor pathway (NGF);; Oxidative Stress Induced Gene Expression Via Nrf2;; PDGF Signaling Pathway;; Pertussis toxin-insensitive CCR5 Signaling in Macrophage;; Repression of Pain Sensation by the Transcriptional Regulator DREAM;; Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy;; Signaling Pathway from G-Protein Families;; T Cell Receptor Signaling Pathway;; Toll-Like Receptor Pathway;; TPO Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell B cell receptor signaling pathway;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signalin;; MAPK signaling pathway;; T cell receptor signaling pathway;; Toll-like receptor signaling pathway cellular response to extracellular stimulus;; DNA binding;; nervous system development;; nucleus;; nucleus;; nucleus;; positive regulation of transcription from RNA polymerase II promoter;; protein dimerization activity;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; response to drug;; sequence-specific DNA binding;; transcription factor activity;; transcription factor activity;; transcription factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell communication;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; response to chemical stimulus;; response to external stimulus 252.8322 182.6350 252.8019 90.6081 135.0477 114.8268 0.011265293 1.01817 7.82557 6.80740 1344785 1423161_s_at chr2:116871176-116871377 2 E5 UGA Mm.245890 114715 RP23-224B9.2 Spred1 Sprouty protein with EVH-1 domain 1, related sequence Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak- inactivation of MAPK activity;; membrane;; multicellular organismal development;; nucleus;; plasma membrane;; protein binding;; regulation of signal transduction;; stem cell factor receptor binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding protein binding biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 1930.4609 1073.6294 1270.5859 650.0516 387.2531 700.7965 0.024246556 1.29996 10.43143 9.13147 1333272 1423265_at chr19:32551765-32581351 19 C1 RSQ Mm.255116 NM_010799 1 1 17330 Minpp1 multiple inositol polyphosphate histidine phosphatase 1 (Minpp1), mRNA. Inositol phosphate metabolism CLASS Metabolism; Carbohydrate Metabolism; Inositol phosphate meta acid phosphatase activity;; endoplasmic reticulum;; hydrolase activity;; membrane;; multiple inositol-polyphosphate phosphatase activity;; plasma membrane cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle catalytic activity hydrolase activity 770.6776 687.0119 1061.8679 301.0549 471.3054 441.1740 0.018610223 1.05565 9.68885 8.63320 1333311 1423315_at chr7:15468159-15476856 7 A2 RSQ Mm.7660 NM_133234 1 1 170770 Bbc3 BCL2 binding component 3 (Bbc3), mRNA. p53 signaling pathway CLASS Cellular Processes; Cell Growth and Death; p53 signaling pathway [PA activation of caspase activity;; apoptosis;; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;; induction of apoptosis;; mitochondrial envelope;; mitochondrion;; negative regulation of cell growth;; negative regulation of growth;; positive regulation of apoptosis;; protein binding;; regulation of apoptosis;; release of cytochrome c from mitochondria cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle envelope;; organelle part binding protein binding biological regulation;; cellular process;; developmental process;; growth;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; cell communication;; cell death;; cell growth;; cellular component organization;; cellular developmental process;; cellular response to stimulus;; death;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of growth;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of growth;; regulation of molecular function;; response to stress 2733.3459 2829.8858 4124.9856 1072.4504 947.5677 1894.1799 0.020233051 1.35034 11.63105 10.28071 1344870 1423622_a_at chr3:66034079-66046154 3 E1 RSQ Mm.175612 NM_019937 1 1 56706 Ccnl1 cyclin L1 (Ccnl1), mRNA. nucleus;; regulation of transcription, DNA-dependent;; transcription;; transcription elongation factor complex cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 633.4453 629.8317 899.3940 275.9750 383.8636 392.7014 0.011860659 1.03619 9.47290 8.43671 1333620 1423693_at chr15:100502458-100515952 15 F1 RSQ Mm.2131 NM_033612 1 1 109901 Ela1 elastase 1, pancreatic (Ela1), mRNA. hydrolase activity;; peptidase activity;; serine-type peptidase activity catalytic activity hydrolase activity 553.0148 429.4835 555.7426 243.8885 178.3228 310.9910 0.014024679 1.09558 8.99197 7.89638 1344906 1423747_a_at chr2:71674110-71703513 2 C2 RSQ Mm.34411 NM_172665 1 1 228026 RP23-5K9.5 Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 (Pdk1), nuclear gene encoding mitochondrial protein, mRNA. Fc epsilon RI signaling pathway CLASS Cellular Processes; Immune System; T cell receptor signali;; T cell receptor signaling pathway ATP binding;; carbohydrate metabolic process;; glucose metabolic process;; intracellular signaling cascade;; kinase activity;; mitochondrion;; peptidyl-histidine phosphorylation;; plasma membrane;; protein binding;; protein histidine kinase activity;; pyruvate dehydrogenase (acetyl-transferring) kinase activity;; signal transduction;; transferase activity;; two-component sensor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; catalytic activity;; molecular transducer activity nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process cell communication;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process 945.2342 699.3693 1009.7821 335.9373 382.8847 495.8670 0.0082402853 1.12921 9.77142 8.64221 1333665 1423760_at chr2:102613428-102613853 2 E2 UGA Mm.423621 12505 RP23-203N8.3 Cd44 CD44 antigen Adhesion Molecules on Lymphocyte;; Monocyte and its Surface Molecules;; Neutrophil and Its Surface Molecules ECM-receptor interaction;; Hematopoietic cell lineage CLASS Environmental Information Processing; Signaling Molecules and I basolateral plasma membrane;; binding;; cell adhesion;; cell surface;; external side of plasma membrane;; healing during inflammatory response;; hyaluronic acid binding;; hyaluronic acid binding;; integral to membrane;; membrane;; plasma membrane;; protein binding;; receptor activity;; ureteric bud branching cell;; cell part cell part;; cell surface;; membrane;; membrane part binding;; molecular transducer activity carbohydrate binding;; pattern binding;; protein binding;; signal transducer activity biological adhesion;; cellular process;; developmental process;; multicellular organismal process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; multicellular organismal development;; response to external stimulus;; response to stress 467.0401 547.5557 520.7494 220.3848 179.9661 375.9557 0.031426443 1.05294 8.99624 7.94329 1345065 1424437_s_at chr9:44024184-44039239 9 A5.2 RSQ Mm.101876 NM_138955 1 1 192663 Abcg4 ATP-binding cassette, sub-family G (WHITE), member 4 (Abcg4), mRNA. ABC transporters CLASS Environmental Information Processing; Membrane Transport; ABC transporter ATP binding;; endosome;; nucleotide binding;; positive regulation of cholesterol biosynthetic process;; regulation of transcription cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleotide binding biological regulation;; cellular process;; metabolic process;; positive regulation of biological process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 84.1616 74.4979 91.7100 35.6237 46.7404 36.8655 0.00204223 1.07589 6.37774 5.30186 1345125 1424719_a_at chr11:104126497-104138605 11 E1 UGA Mm.1287 17762 RP23-136D4.1 Mapt Microtubule-associated protein tau Bioactive Peptide Induced Signaling Pathway;; Deregulation of CDK5 in Alzheimers Disease Alzheimer's disease CLASS Environmental Information Processing; Signal Transduction; MAPK signal;; MAPK signaling pathway axon;; cell projection;; cytoplasm;; cytoskeleton;; membrane;; microtubule;; negative regulation of microtubule depolymerization;; plasma membrane;; protein binding cell;; cell part;; organelle;; organelle part cell part;; cell projection;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; non-membrane-bounded organelle;; organelle part binding protein binding biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; microtubule-based process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 165.0857 149.9599 208.9557 84.8274 51.0793 120.1475 0.045707014 1.10426 7.43419 6.32993 1345182 1424917_a_at chr11:109389610-109427479 11 E1 RSQ Mm.35817 NM_145940 1 1 52639 RP23-465A12.6 Wipi1 WD repeat domain, phosphoinositide interacting 1 (Wipi1), mRNA. autophagy;; cytoplasmic vesicle;; endosome;; Golgi apparatus;; pre-autophagosomal structure;; receptor binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; vesicle binding protein binding cellular process;; metabolic process catabolic process;; cellular metabolic process 728.5342 363.2525 430.1986 287.3714 175.0920 190.0417 0.033540911 1.19121 8.92085 7.72964 1345189 1424942_a_at chr15:61815006-61820027 15 D1 RSQ Mm.2444 NM_010849 1 1 17869 Myc myelocytomatosis oncogene (Myc), mRNA. Cadmium induces DNA synthesis and proliferation in macrophages;; CTCF: First Multivalent Nuclear Factor;; Erk1/Erk2 Mapk Signaling pathway;; IL-2 Receptor Beta Chain in T cell Activation;; Inhibition of Cellular Proliferation by Gleevec;; MAPKinase Signaling Pathway;; Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;; Overview of telomerase protein component gene hTert Transcriptional Regulation;; p38 MAPK Signaling Pathway;; Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy;; Telomeres, Telomerase, Cellular Aging, and Immortality;; Tumor Suppressor Arf Inhibits Ribosomal Biogenesis;; WNT Signaling Pathway Acute myeloid leukemia;; Bladder cancer;; Chronic myeloid leukemia;; Colorectal cancer;; Endometrial cancer;; ErbB signaling pathway;; Jak-STAT signaling pathway;; MAPK signaling pathway;; Small cell lung cancer CLASS Environmental Information Processing; Signal Transduction; MAPK sig;; TGF-beta signaling pathway;; Thyroid cancer;; Wnt signaling pathway activation of caspase activity;; activation of pro-apoptotic gene products;; activation of pro-apoptotic gene products;; B cell apoptosis;; detection of mechanical stimulus involved in sensory perception of sound;; DNA binding;; DNA fragmentation during apoptosis;; induction of apoptosis by intracellular signals;; induction of apoptosis by intracellular signals;; middle ear morphogenesis;; negative regulation of survival gene product expression;; negative regulation of survival gene product expression;; nuclear body;; nucleus;; nucleus;; pigmentation;; positive regulation of B cell apoptosis;; positive regulation of catalytic activity;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; positive regulation of cell proliferation;; positive regulation of transcription from RNA polymerase II promoter;; protein binding;; protein binding;; protein processing;; regulation of apoptosis;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; release of cytochrome c from mitochondria;; response to alkaloid;; response to radiation;; response to radiation;; skeletal system morphogenesis;; spindle;; transcription;; transcription factor activity;; transcription regulator activity cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle lumen;; organelle part binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; pigmentation;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; catabolic process;; cell communication;; cell death;; cell proliferation;; cellular component organization;; cellular metabolic process;; death;; detection of stimulus;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of metabolic process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of molecular function;; response to abiotic stimulus;; response to chemical stimulus;; response to external stimulus;; system process 1343.0538 1084.0832 1130.7563 482.3632 408.1011 390.9890 0.00036935032 1.47296 10.20554 8.73258 1334713 1425145_at chr1:40385253-40409958 1 B RSQ Mm.289824 NM_001025602 1 1 17082 Il1rl1 interleukin 1 receptor-like 1 (Il1rl1), transcript variant 1, mRNA. extracellular region;; innate immune response;; integral to membrane;; interleukin-1 receptor activity;; interleukin-33 binding;; interleukin-33 receptor activity;; intrinsic to membrane;; membrane;; negative regulation of I-kappaB kinase/NF-kappaB cascade;; plasma membrane;; protein binding;; receptor activity;; signal transduction;; transmembrane receptor activity cell;; cell part;; extracellular region cell part;; membrane;; membrane part binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; immune system process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell communication;; immune response;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; response to stress 307.6099 220.6295 147.0669 99.2905 74.9919 105.1018 0.023316763 1.22429 7.75026 6.52596 1345753 1426165_a_at chr8:48116265-48137534 8 B1.1 RSQ Mm.34405 NM_009810 1 1 12367 Casp3 caspase 3 (Casp3), mRNA. Apoptotic DNA fragmentation and tissue homeostasis;; Apoptotic Signaling in Response to DNA Damage;; B Cell Survival Pathway;; Caspase Cascade in Apoptosis;; D4-GDI Signaling Pathway;; FAS signaling pathway ( CD95 );; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Role of Mitochondria in Apoptotic Signaling;; Stress Induction of HSP Regulation;; TNFR1 Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Alzheimer's disease;; Amyotrophic lateral sclerosis (ALS);; Apoptosis;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signalin;; Dentatorubropallidoluysian atrophy (DRPLA);; Huntington's disease;; MAPK signaling pathway;; Natural killer cell mediated cytotoxicity;; p53 signaling pathway;; Parkinson's disease apoptosis;; apoptosis;; apoptosis;; B cell homeostasis;; cell fate commitment;; cyclin-dependent protein kinase inhibitor activity;; cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; cytoplasm;; DNA fragmentation during apoptosis;; heart development;; hydrolase activity;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis by oxidative stress;; induction of apoptosis via death domain receptors;; keratinocyte differentiation;; negative regulation of activated T cell proliferation;; negative regulation of apoptosis;; negative regulation of B cell proliferation;; negative regulation of cell cycle;; negative regulation of cyclin-dependent protein kinase activity;; neuron apoptosis;; peptidase activity;; peptidase activity;; peptidase activity;; peptidase activity;; protein binding;; proteolysis;; release of cytochrome c from mitochondria;; response to DNA damage stimulus;; response to UV;; response to UV;; response to wounding;; sensory perception of sound;; T cell homeostasis cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; hydrolase activity;; kinase regulator activity;; protein binding biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell activation;; cell communication;; cell cycle;; cell death;; cell fate commitment;; cell proliferation;; cellular component organization;; cellular developmental process;; cellular metabolic process;; death;; leukocyte activation;; leukocyte homeostasis;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of immune system process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of molecular function;; response to abiotic stimulus;; response to external stimulus;; response to stress;; system process 1573.9589 1293.1887 1656.3973 713.9075 529.4709 1090.8861 0.034759661 1.01048 10.55024 9.53976 1335315 1426297_at chr10:79812721-79836736 10 C1 RSQ Mm.3406 NM_011548 1 1 21423 Tcfe2a transcription factor E2a (Tcfe2a), mRNA. DNA binding;; nucleus;; protein binding;; protein heterodimerization activity;; protein homodimerization activity;; regulation of transcription;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription;; transcription factor activity;; transcription factor complex;; transcription regulator activity cell;; cell part;; macromolecular complex;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1015.3079 961.5193 817.2706 392.7565 361.7954 596.4474 0.011243949 1.07826 9.85718 8.77892 1345849 1426501_a_at chr3:127781934-127790411 3 G2 RSQ Mm.31852 NM_145133 2 2 211550 Tifa TRAF-interacting protein with forkhead-associated domain (Tifa), mRNA. I-kappaB kinase/NF-kappaB cascade;; protein binding binding protein binding biological regulation;; cellular process;; regulation of biological process cell communication;; regulation of biological process;; regulation of cellular process 294.1167 309.1391 250.5266 121.2879 120.7393 97.8751 0.00063149161 1.33009 8.14706 6.81697 1345855 1426516_a_at chr12:16562115-16615250 12 A1.1 RSQ Mm.153625 NM_172950 2 1 14245 Lpin1 lipin 1 (Lpin1), transcript variant 1, mRNA. actin cytoskeleton reorganization;; cellular response to insulin stimulus;; lipid metabolic process;; nucleus;; phosphatidate phosphatase activity;; regulation of fat cell differentiation;; ruffle organization cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle catalytic activity hydrolase activity biological regulation;; cellular process;; developmental process;; metabolic process;; regulation of biological process;; response to stimulus actin filament-based process;; anatomical structure development;; anatomical structure morphogenesis;; cellular component organization;; cellular developmental process;; cellular response to stimulus;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; response to chemical stimulus;; response to endogenous stimulus 1133.3641 1125.5428 1295.2681 555.7174 577.4197 594.5298 0.00013240204 1.03818 10.20728 9.16910 1335639 1426757_at chr3:108202117-108214683 3 F3 RSQ Mm.274335 NM_028779 1 1 109674 RP23-89M15.1 Ampd2 adenosine monophosphate deaminase 2 (isoform L) (Ampd2), mRNA. Purine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] AMP deaminase activity;; deaminase activity;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;; nucleotide metabolic process;; purine base metabolic process;; purine ribonucleoside monophosphate biosynthetic process catalytic activity deaminase activity;; hydrolase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 1766.7266 1843.8665 1804.5321 748.1543 741.2043 794.3149 4.1509624e-06 1.24610 10.81760 9.57150 1335678 1426810_at chr6:71518549-71562078 6 C1 RSQ Mm.260479 NM_173001 1 1 104263 Jmjd1a jumonji domain containing 1A (Jmjd1a), transcript variant 1, mRNA. chromatin modification;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 550.4111 627.0002 2330.6453 144.0300 102.4487 230.2243 0.024376516 2.62911 9.86107 7.23196 1335932 1427126_at chr17:34564705-34565084 17 B1 UG5 Mm.372314 15511 Hspa1b Heat shock protein 1B anti-apoptosis;; ATP binding;; DNA repair;; intracellular;; mitochondrial matrix;; mitochondrion;; mitochondrion;; negative regulation of caspase activity;; nucleotide binding;; protein binding;; response to heat;; response to heat;; response to stress;; telomere maintenance cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding nucleotide binding;; protein binding biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell death;; cellular component organization;; cellular metabolic process;; cellular response to stimulus;; death;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 574.9192 881.9367 3276.5617 179.7712 105.2040 268.6614 0.030726479 2.78433 10.20990 7.42557 1346011 1427127_x_at chr17:34564590-34565084 17 B1 UG5 Mm.372314 15511 Hspa1b Heat shock protein 1B anti-apoptosis;; ATP binding;; DNA repair;; intracellular;; mitochondrial matrix;; mitochondrion;; mitochondrion;; negative regulation of caspase activity;; nucleotide binding;; protein binding;; response to heat;; response to heat;; response to stress;; telomere maintenance cell;; cell part;; membrane-enclosed lumen;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle lumen;; organelle part binding nucleotide binding;; protein binding biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process;; response to stimulus cell death;; cellular component organization;; cellular metabolic process;; cellular response to stimulus;; death;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of molecular function;; response to abiotic stimulus;; response to stress 211.2263 184.8654 288.2397 88.4549 109.9656 104.4103 0.0054982661 1.15673 7.80803 6.65130 1335942 1427143_at chr1:136376605-136449288 1 E4 RSQ Mm.28995 NM_152895 1 1 75605 Jarid1b jumonji, AT rich interactive domain 1B (Rbp2 like) (Jarid1b), mRNA. chromatin modification;; DNA binding;; intracellular;; iron ion binding;; metal ion binding;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; oxidoreductase activity;; protein binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 47.2081 67.8951 83.2824 22.2329 44.8110 25.3412 0.044443025 1.13411 6.00871 4.87461 1335968 1427174_at RSQ Mm.425123 XM_902322 2 2 665211 RP24-87L14.1 OTTMUSG00000016327 PREDICTED: predicted gene, OTTMUSG00000016327, transcript variant 25 (OTTMUSG00000016327), mRNA. metal ion binding;; zinc ion binding binding ion binding 1171.6424 1434.3120 1431.1709 405.8504 388.0652 753.9579 0.011112289 1.44671 10.38781 8.94110 1336077 1427305_at chrX:159763891-159778020 X F5 RSQ Mm.3781 NM_011081 1 1 18700 RP23-202H24.3 Piga phosphatidylinositol glycan anchor biosynthesis, class A (Piga), mRNA. Glycan structures - biosynthesis 2 CLASS Metabolism; Glycan Biosynthesis and Metabolism; Glycosy;; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis biosynthetic process;; endoplasmic reticulum;; GPI anchor biosynthetic process;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 2310.8903 1896.1082 2067.2609 913.3439 1058.2441 997.9774 0.00047503511 1.07708 11.02552 9.94844 1346054 1427334_s_at chr6:149266600-149292826 6 G3 RSQ Mm.333515 NM_026054 1 1 67246 RP23-214L4.1 2810474O19Rik RIKEN cDNA 2810474O19 gene (2810474O19Rik), mRNA. 4354.1192 3352.4112 4045.3441 1518.1322 1309.2002 1340.0108 0.00033474312 1.49020 11.92707 10.43686 1336585 1428082_at chr19:55306618-55349878 19 D2 RSQ Mm.292056 NM_027976 1 1 433256 Acsl5 acyl-CoA synthetase long-chain family member 5 (Acsl5), mRNA. Adipocytokine signaling pathway CLASS Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:;; Fatty acid metabolism;; PPAR signaling pathway catalytic activity;; endoplasmic reticulum;; fatty acid metabolic process;; integral to membrane;; ligase activity;; lipid metabolic process;; long-chain-fatty-acid-CoA ligase activity;; magnesium ion binding;; membrane;; metabolic process;; microsome;; mitochondrial inner membrane;; mitochondrial outer membrane;; mitochondrion;; peroxisome cell;; cell part;; envelope;; organelle;; organelle part cell fraction;; cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding;; catalytic activity ion binding;; ligase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 1168.6438 1682.6402 1630.6767 656.7982 796.8412 656.7971 0.0050360401 1.07388 10.52613 9.45225 1336586 1428083_at chr19:5842301-5845478 19 A RSQ NR_003513 1 1 66961 2310043N10Rik RIKEN cDNA 2310043N10 gene (2310043N10Rik) on chromosome 19. 767.1992 655.2856 904.0264 321.8368 421.9826 362.7641 0.0036686931 1.06852 9.58655 8.51804 1336997 1429800_at chr7:24937446-24939023 7 A3 UGA Mm.379255 210172 Zfp526 RIKEN cDNA 9130221H12 gene DNA binding;; intracellular;; metal ion binding;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 82.5159 66.5490 123.1791 22.7781 36.6041 37.3612 0.013310123 1.48019 6.45585 4.97566 1346596 1431024_a_at chr13:13855917-13991729 13 A1 RSQ Mm.439784 NM_198122 2 1 94246 RP23-332P8.1 Arid4b AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 2, mRNA. chromatin;; chromatin assembly or disassembly;; chromatin binding;; DNA binding;; intracellular;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 200.2212 195.4169 171.8660 71.2942 76.0469 62.2348 0.00019189406 1.43894 7.56033 6.12139 1337078 1431031_at chr13:13855917-13991729 13 A1 RSQ Mm.439784 NM_198122 2 1 94246 RP23-332P8.1 Arid4b AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 2, mRNA. chromatin;; chromatin assembly or disassembly;; chromatin binding;; DNA binding;; intracellular;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 392.1961 861.2268 740.3777 82.8220 129.6973 72.6501 0.0029710715 2.77465 9.29927 6.52461 1346678 1431591_s_at chr17:45870111-45870764 17 C RSQ Mm.460266 XR_005074 2 1 677168 LOC677168 PREDICTED: similar to ISG15 ubiquitin-like modifier (LOC677168), misc RNA. 2994.9434 3539.5837 6747.1481 1781.1210 1541.0506 1816.8285 0.02469784 1.28075 12.01925 10.73849 1346941 1433604_x_at chr7:126586759-126587185 7 F3 UG5 Mm.275831 11674 Aldoa Aldolase A, fructose-bisphosphate Fructose and mannose metabolism CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeo;; Glycolysis / Gluconeogenesis;; Pentose phosphate pathway catalytic activity;; flagellum;; fructose-bisphosphate aldolase activity;; glycolysis;; lyase activity;; metabolic process cell;; cell part cell part;; cell projection catalytic activity lyase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 727.6974 618.6428 806.6991 180.0165 197.5506 201.9123 0.00010359381 1.88680 9.47868 7.59188 1337310 1433645_at chr4:53588411-53588785 4 B2 UGA Mm.439778 Transcribed locus 663.6086 527.0792 496.6160 232.3698 178.2044 315.2237 0.0099253975 1.24472 9.12402 7.87930 1337328 1433702_at chr19:29675879-29714417 19 C1 RSQ Mm.267131 NM_001081213 1 1 226090 Ermp1 endoplasmic reticulum metallopeptidase 1 (Ermp1), mRNA. endoplasmic reticulum;; hydrolase activity;; integral to membrane;; membrane;; metal ion binding;; metallopeptidase activity;; peptidase activity;; proteolysis;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; ion binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 325.7345 535.2141 454.7462 186.1456 274.3638 131.2883 0.033255663 1.18787 8.74681 7.55894 1346968 1433757_a_at chr14:30014737-30014890 14 B UG5 Mm.298728 64652 Nisch Nischarin actin cytoskeleton organization;; apoptosis;; cell communication;; cytoplasm;; cytosol;; endosome;; integrin binding;; membrane;; negative regulation of cell migration;; phosphoinositide binding;; plasma membrane;; protein binding;; Rac protein signal transduction;; receptor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; molecular transducer activity lipid binding;; protein binding;; signal transducer activity biological regulation;; cellular process;; developmental process;; localization;; locomotion;; negative regulation of biological process;; regulation of biological process actin filament-based process;; cell communication;; cell death;; cell motility;; cell motion;; cellular component organization;; death;; localization of cell;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of localization;; regulation of locomotion 1256.2273 1031.0563 1318.4049 411.7406 217.9539 515.7187 0.011013459 1.73515 10.22312 8.48797 1346988 1433963_a_at chr19:7066546-7066733 19 A UGA Mm.157591 108101 Fermt3 Fermitin family homolog 3 (Drosophila) cell adhesion;; cytoplasm;; cytoskeleton;; podosome;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding protein binding biological adhesion;; cellular process cell adhesion 1192.8174 1092.3754 1543.8281 707.7406 438.6856 695.1602 0.016654173 1.07346 10.30190 9.22844 1346989 1433964_s_at chr19:7066021-7086475 19 A RSQ Mm.157591 NM_153795 1 1 108101 Fermt3 fermitin family homolog 3 (Drosophila) (Fermt3), mRNA. cell adhesion;; cytoplasm;; cytoskeleton;; podosome;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding protein binding biological adhesion;; cellular process cell adhesion 301.7419 308.0977 278.9733 119.3123 103.1819 183.7612 0.0098708005 1.17302 8.20947 7.03644 1337521 1434390_at chr1:180158209-180158360 1 H4 UGA Mm.86589 66359 2310005N03Rik RIKEN cDNA 2310005N03 gene integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 477.1818 370.2330 482.8441 150.1669 187.2432 179.0038 0.0010048876 1.36102 8.78203 7.42101 1337527 1434403_at chr11:19923448-19923876 11 A3.1 UGA Mm.266627 114716 Spred2 Sprouty-related, EVH1 domain containing 2 Jak-STAT signaling pathway CLASS Environmental Information Processing; Signal Transduction; Jak- cytoplasm;; cytoplasmic vesicle;; inactivation of MAPK activity;; membrane;; multicellular organismal development;; plasma membrane;; protein binding;; regulation of signal transduction;; stem cell factor receptor binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; vesicle binding protein binding biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 1019.5275 959.2464 923.1261 393.7682 438.6599 447.6510 7.6227388e-05 1.18181 9.91661 8.73480 1337545 1434479_at chr2:27860718-27861136 2 A3 RSQ Mm.7281 NM_015734 1 1 12831 Col5a1 collagen, type V, alpha 1 (Col5a1), mRNA. ECM-receptor interaction CLASS Environmental Information Processing; Signaling Molecules and Int;; Focal adhesion basement membrane;; blood vessel development;; cell adhesion;; collagen;; collagen;; collagen fibril organization;; collagen fibril organization;; extracellular matrix;; extracellular matrix structural constituent;; extracellular region;; heart morphogenesis;; heparin binding;; platelet-derived growth factor binding;; protein binding;; proteinaceous extracellular matrix;; regulation of cellular component organization;; skin development;; structural molecule activity extracellular region;; extracellular region part extracellular matrix;; extracellular matrix part;; extracellular region part binding;; structural molecule activity carbohydrate binding;; extracellular matrix structural constituent;; pattern binding;; protein binding biological adhesion;; biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; cellular component organization;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 1920.7672 2599.1548 3959.8344 1222.9993 941.6776 1134.6147 0.015504351 1.30641 11.40084 10.09443 1347101 1434799_x_at chr7:126586576-126586908 7 F3 UG5 Mm.275831 11674 Aldoa Aldolase A, fructose-bisphosphate Fructose and mannose metabolism CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeo;; Glycolysis / Gluconeogenesis;; Pentose phosphate pathway catalytic activity;; flagellum;; fructose-bisphosphate aldolase activity;; glycolysis;; lyase activity;; metabolic process cell;; cell part cell part;; cell projection catalytic activity lyase activity cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 443.2631 332.7160 371.4587 116.1059 86.0931 84.3923 0.0004688875 2.00702 8.56907 6.56205 1337731 1435133_at chr4:59283603-59316887 4 B3 RSQ Mm.198803 NM_011673 1 1 22234 RP23-57N22.4 Ugcg UDP-glucose ceramide glucosyltransferase (Ugcg), mRNA. Glycan structures - biosynthesis 2 CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [;; Sphingolipid metabolism ceramide glucosyltransferase activity;; endoplasmic reticulum;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity 1138.5333 854.8229 808.7719 474.6866 314.0975 521.8673 0.014942512 1.11286 9.85068 8.73781 1337818 1435524_at chr3:123499623-123500314 3 G1 UGA Mm.260791 CDNA clone IMAGE:1196043 579.9329 660.6578 642.0610 284.5852 223.2050 265.1940 0.0004077414 1.28941 9.29136 8.00195 1337863 1435768_at chr13:13855917-13991729 13 A1 RSQ Mm.439784 NM_198122 2 1 94246 RP23-332P8.1 Arid4b AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 2, mRNA. chromatin;; chromatin assembly or disassembly;; chromatin binding;; DNA binding;; intracellular;; nucleic acid binding;; nucleus;; regulation of transcription, DNA-dependent;; transcription cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding chromatin binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 971.5909 1568.1192 1232.0137 342.1073 396.4895 671.0379 0.015002542 1.45538 10.26861 8.81323 1347257 1435866_s_at chr11:58771333-58771769 11 B1.3 UGA Mm.212549 319162 RP23-441I8.12 Hist3h2a Histone cluster 3, H2a Systemic lupus erythematosus CLASS Human Diseases; Immune Disorders; Systemic lupus erythematosu chromosome;; DNA binding;; metal ion binding;; nucleosome;; nucleosome assembly;; nucleus;; zinc ion binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein-DNA complex binding ion binding;; nucleic acid binding cellular process cellular component organization 193.9606 441.8474 446.2613 88.2159 136.7166 77.7337 0.019007178 1.78343 8.39626 6.61283 1347312 1436362_x_at IPA Unknown 395.5662 331.2928 358.7146 161.3067 107.9662 221.7795 0.017784904 1.20178 8.49548 7.29369 1337985 1436427_at chr13:34912938-34913337 13 A3.3 UGA Mm.475929 Transcribed locus 2369.0000 1930.8774 2344.1047 1174.2301 806.0505 1148.2858 0.0053384981 1.10081 11.10664 10.00583 1338178 1437626_at chr17:84092249-84096273 17 E4 RSQ Mm.259321 NM_001001806 1 1 12193 Zfp36l2 zinc finger protein 36, C3H type-like 2 (Zfp36l2), mRNA. cytoplasm;; DNA binding;; metal ion binding;; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;; nucleic acid binding;; nucleus;; regulation of mRNA stability;; RNA binding;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding biological regulation;; cellular process;; metabolic process;; regulation of biological process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 827.3088 978.0013 1146.3023 675.6957 374.9996 451.3625 0.024245978 1.00654 9.92958 8.92304 1347646 1437708_x_at chr4:149891104-149901753 4 E2 RSQ Mm.273930 NM_009498 1 1 22319 RP23-455G15.3 Vamp3 vesicle-associated membrane protein 3 (Vamp3), mRNA. SNARE interactions in vesicular transport CLASS Genetic Information Processing; Folding, Sorting calcium ion-dependent exocytosis;; cell junction;; integral to membrane;; membrane;; synapse;; synaptosome;; vesicle-mediated transport cell;; cell part;; synapse cell fraction;; cell part;; membrane;; membrane part cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; transport;; vesicle-mediated transport 174.8438 252.4293 216.7183 114.4471 140.5002 73.7360 0.033128665 1.00402 7.72978 6.72575 1347696 1437901_a_at chr13:18724763-18874268 13 A2 RSQ Mm.27389 NM_172120 1 1 218035 Vps41 vacuolar protein sorting 41 (yeast) (Vps41), mRNA. early endosome;; intracellular protein transport;; late endosome;; metal ion binding;; microtubule;; microtubule binding;; protein binding;; protein transport;; transport;; vesicle-mediated transport;; zinc ion binding cell;; cell part;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part binding ion binding;; protein binding cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; establishment of protein localization;; macromolecule localization;; transport;; vesicle-mediated transport 440.5070 351.2256 510.8325 191.0358 190.3498 263.7655 0.010182349 1.01422 8.74533 7.73111 1347762 1438167_x_at chr11:59607944-59625968 11 B1.3 RSQ Mm.339640 NM_146018 1 1 216805 RP23-180B18.1 Flcn folliculin (Flcn), mRNA. Renal cell carcinoma CLASS Human Diseases; Cancers; Renal cell carcinoma [PATH:mmu05211] cell cycle;; cytoplasm;; negative regulation of cell cycle cell;; cell part cell part;; intracellular;; intracellular part biological regulation;; cellular process;; negative regulation of biological process;; regulation of biological process cell cycle;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process 150.0393 190.7932 179.2593 62.8338 74.7399 136.2004 0.047299351 1.00137 7.43032 6.42895 1338335 1438700_at chr2:90568525-90569058 2 E1 UG5 Mm.475893 55935 RP23-322I11.2 Fnbp4 Formin binding protein 4 protein binding binding protein binding 1663.5448 1535.3560 1858.1182 686.3840 605.8046 789.8875 0.00070828828 1.28431 10.71468 9.43036 1347952 1438941_x_at chr3:108202136-108202182 3 F2.3 UGA Mm.274335 109674 RP23-89M15.1 Ampd2 Adenosine monophosphate deaminase 2 (isoform L) Purine metabolism CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] AMP deaminase activity;; deaminase activity;; hydrolase activity;; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;; nucleotide metabolic process;; purine base metabolic process;; purine ribonucleoside monophosphate biosynthetic process catalytic activity deaminase activity;; hydrolase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 670.3490 1108.0868 2138.0596 435.1481 351.8131 428.9856 0.036287293 1.53197 10.18824 8.65627 1348045 1439375_x_at chr7:126586438-126586796 7 F3 IPA Aldo1 aldolase 1, A isoform 1593.6766 930.9295 916.5686 238.1921 82.3952 37.0241 0.01156458 3.62330 10.11359 6.49029 1348076 1439422_a_at chr4:154806117-154810429 4 E2 RSQ Mm.29140 NM_026125 1 1 67389 RP23-118E21.2 C1qdc2 C1q domain containing 2 (C1qdc2), mRNA. extracellular region extracellular region 629.5898 982.5273 1200.7504 177.0976 256.1264 153.5747 0.0031070215 2.24548 9.82278 7.57730 1338727 1448154_at chr14:50827231-50835302 14 C1 RSQ Mm.26722 NM_013864 1 1 29811 Ndrg2 N-myc downstream regulated gene 2 (Ndrg2), mRNA. cell differentiation;; cytoplasm;; multicellular organismal development;; nervous system development cell;; cell part cell part;; intracellular;; intracellular part cellular process;; developmental process;; multicellular organismal process anatomical structure development;; cellular developmental process;; multicellular organismal development 1090.2771 682.9022 769.0642 274.8054 238.4863 379.4766 0.0059992071 1.50836 9.69766 8.18930 1348220 1448405_a_at chr2:125364540-125367084 2 F1 RSQ Mm.425101 NM_025613 1 1 58521 RP23-323D9.2 Eid1 EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA. cell cycle;; cell differentiation;; cytoplasm;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; specific transcriptional repressor activity;; transcription;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1516.9324 1093.5698 1590.9925 526.3291 531.9663 734.3550 0.0061134387 1.22738 10.43249 9.20512 1338919 1448406_at chr2:125364540-125367084 2 F1 RSQ Mm.425101 NM_025613 1 1 58521 RP23-323D9.2 Eid1 EP300 interacting inhibitor of differentiation 1 (Eid1), mRNA. cell cycle;; cell differentiation;; cytoplasm;; negative regulation of transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; specific transcriptional repressor activity;; transcription;; transcription corepressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; developmental process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cell cycle;; cellular developmental process;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 172.6482 87.0249 186.6941 71.7299 58.1697 66.4431 0.036749328 1.11294 7.13986 6.02692 1348250 1448551_a_at chr3:84250548-84251101 3 F1 UGA Mm.44876 80890 Trim2 Tripartite motif-containing 2 cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding 1214.1545 897.9774 916.1084 613.0704 448.8453 385.0238 0.011226287 1.07895 9.96522 8.88626 1339039 1448559_at chr17:35431409-35440840 17 B1 RSQ Mm.2931 NM_008027 1 1 14251 Flot1 flotillin 1 (Flot1), mRNA. Insulin signaling pathway CLASS Cellular Processes; Endocrine System; Insulin signaling pathway flotillin complex;; membrane;; membrane raft;; plasma membrane cell;; cell part;; macromolecular complex cell part;; membrane;; membrane part;; protein complex 3067.0141 2564.7696 2972.3392 885.5297 693.6111 464.0251 0.0017048108 2.11939 11.48154 9.36215 1339145 1448687_at chr4:154806117-154810429 4 E2 RSQ Mm.29140 NM_026125 1 1 67389 RP23-118E21.2 C1qdc2 C1q domain containing 2 (C1qdc2), mRNA. extracellular region extracellular region 15171.1885 11636.8119 15085.4602 6536.4917 5165.5707 9729.5264 0.026970528 1.00639 13.75878 12.75239 1348284 1448739_x_at chr17:33562452-33566095 17 B1 RSQ Mm.324762 NM_011296 9 7 20084 Rps18 ribosomal protein S18 (Rps18), mRNA. Ribosome CLASS Genetic Information Processing; Translation; Ribosome [PATH:mmu03010] cytoplasm;; intracellular;; ribonucleoprotein complex;; ribosome;; RNA binding;; rRNA binding;; structural constituent of ribosome;; translation cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle;; ribonucleoprotein complex binding;; structural molecule activity nucleic acid binding;; structural constituent of ribosome cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 734.4922 813.2754 716.1396 397.1589 293.0009 145.0070 0.023138928 1.55466 9.55743 8.00277 1339697 1449358_at chr6:82922066-82995825 6 C3 RSQ Mm.100652 NM_033079 1 1 110958 D6Mm5e DNA segment, Chr 6, Miriam Meisler 5, expressed (D6Mm5e), mRNA. 2083.9249 1956.9185 2436.6077 902.7847 686.5436 968.4602 0.0016303923 1.34971 11.07004 9.72033 1348398 1449410_a_at chr1:162871104-162874004 1 H2.1 RSQ XM_001479454 1 1 100048067 LOC100048067 PREDICTED: hypothetical protein LOC100048067 (LOC100048067), mRNA. 1762.8687 1163.5331 1333.1689 669.7745 449.6684 388.6447 0.0066915458 1.51536 10.44955 8.93419 1340027 1449839_at chr8:48137929-48138449 8 B1.1 UGA Mm.34405 12367 Casp3 Caspase 3 Apoptotic DNA fragmentation and tissue homeostasis;; Apoptotic Signaling in Response to DNA Damage;; B Cell Survival Pathway;; Caspase Cascade in Apoptosis;; D4-GDI Signaling Pathway;; FAS signaling pathway ( CD95 );; HIV-I Nef: negative effector of Fas and TNF;; Induction of apoptosis through DR3 and DR4/5 Death Receptors;; Role of Mitochondria in Apoptotic Signaling;; Stress Induction of HSP Regulation;; TNFR1 Signaling Pathway;; TSP-1 Induced Apoptosis in Microvascular Endothelial Cell Alzheimer's disease;; Amyotrophic lateral sclerosis (ALS);; Apoptosis;; Colorectal cancer CLASS Environmental Information Processing; Signal Transduction; MAPK signalin;; Dentatorubropallidoluysian atrophy (DRPLA);; Huntington's disease;; MAPK signaling pathway;; Natural killer cell mediated cytotoxicity;; p53 signaling pathway;; Parkinson's disease apoptosis;; apoptosis;; apoptosis;; B cell homeostasis;; cell fate commitment;; cyclin-dependent protein kinase inhibitor activity;; cysteine-type endopeptidase activity;; cysteine-type peptidase activity;; cytoplasm;; DNA fragmentation during apoptosis;; heart development;; hydrolase activity;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis;; induction of apoptosis by oxidative stress;; induction of apoptosis via death domain receptors;; keratinocyte differentiation;; negative regulation of activated T cell proliferation;; negative regulation of apoptosis;; negative regulation of B cell proliferation;; negative regulation of cell cycle;; negative regulation of cyclin-dependent protein kinase activity;; neuron apoptosis;; peptidase activity;; peptidase activity;; peptidase activity;; peptidase activity;; protein binding;; proteolysis;; release of cytochrome c from mitochondria;; response to DNA damage stimulus;; response to UV;; response to UV;; response to wounding;; sensory perception of sound;; T cell homeostasis cell;; cell part cell part;; intracellular;; intracellular part binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; hydrolase activity;; kinase regulator activity;; protein binding biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; catabolic process;; cell activation;; cell communication;; cell cycle;; cell death;; cell fate commitment;; cell proliferation;; cellular component organization;; cellular developmental process;; cellular metabolic process;; death;; leukocyte activation;; leukocyte homeostasis;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; negative regulation of immune system process;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; primary metabolic process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of molecular function;; response to abiotic stimulus;; response to external stimulus;; response to stress;; system process 129.3400 112.3855 131.0449 67.0601 54.1633 53.0301 0.0010412062 1.10196 6.95375 5.85179 1340171 1450044_at chr1:59426724-59431501 1 C1.3 RSQ Mm.297906 NM_008057 1 1 14369 Fzd7 frizzled homolog 7 (Drosophila) (Fzd7), mRNA. Basal cell carcinoma CLASS Environmental Information Processing; Signal Transduction; Wnt signal;; Colorectal cancer;; Melanogenesis;; Wnt signaling pathway cell surface receptor linked signal transduction;; G-protein coupled receptor activity;; G-protein coupled receptor protein signaling pathway;; integral to membrane;; membrane;; multicellular organismal development;; non-G-protein coupled 7TM receptor activity;; receptor activity;; signal transducer activity;; signal transduction;; Wnt receptor signaling pathway cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; regulation of biological process cell communication;; multicellular organismal development;; regulation of biological process;; regulation of cellular process 564.4510 580.8329 733.3631 244.3609 382.6708 257.0146 0.0095011884 1.10751 9.28036 8.17285 1348560 1450062_a_at chrX:90788192-90794793 X C3 RSQ Mm.27578 NM_019791 1 1 94275 RP23-272D10.5 Maged1 melanoma antigen, family D, 1 (Maged1), mRNA. cytoplasm;; identical protein binding;; membrane;; plasma membrane;; protein binding;; regulation of transcription from RNA polymerase II promoter;; transcription coactivator activity cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding;; transcription regulator activity protein binding;; transcription activator activity;; transcription cofactor activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1132.6750 1007.0961 1141.7406 370.4443 179.3801 363.1631 0.0053437125 1.91802 10.09284 8.17482 1340189 1450065_at chr8:91184339-91220066 8 C3 RSQ Mm.288206 NM_001109756 4 1 11513 Adcy7 adenylate cyclase 7 (Adcy7), transcript variant 4, mRNA. Calcium signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environ;; Purine metabolism activation of adenylate cyclase activity;; adenylate cyclase activity;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 1208.1440 1446.9361 2056.6766 800.0482 677.1498 767.9213 0.011860291 1.03712 10.58115 9.54403 1348564 1450081_x_at chr7:33910917-33939017 7 B1 RSQ Mm.589 NM_008155 4 4 14751 RP23-349I9.4 Gpi1 glucose phosphate isomerase 1 (Gpi1), mRNA. Glycolysis / Gluconeogenesis;; Pentose phosphate pathway;; Starch and sucrose metabolism CLASS Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeoge cytokine activity;; cytoplasm;; extracellular space;; gluconeogenesis;; glucose metabolic process;; glucose-6-phosphate isomerase activity;; glucose-6-phosphate isomerase activity;; glycolysis;; growth factor activity;; isomerase activity;; protein binding cell;; cell part;; extracellular region;; extracellular region part cell part;; extracellular region part;; extracellular space;; intracellular;; intracellular part binding;; catalytic activity isomerase activity;; protein binding cellular process;; metabolic process biosynthetic process;; catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 133.2747 141.3612 144.3604 75.8023 60.2101 65.4760 0.00049973112 1.06201 7.12501 6.06300 1348565 1450082_s_at chr16:22296492-22354975 16 B1 UGA Mm.155708 104156 Etv5 Ets variant gene 5 IL12 and Stat4 Dependent Signaling Pathway in Th1 Development DNA binding;; nucleus;; organ morphogenesis;; positive regulation of transcription;; regulation of transcription, DNA-dependent;; sequence-specific DNA binding;; transcription activator activity;; transcription factor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; transcription activator activity;; transcription factor activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; positive regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 743.7819 524.5932 342.8951 160.7587 110.7501 85.7069 0.0066906854 2.15139 8.99847 6.84709 1348607 1450194_a_at chr10:20814345-20850400 10 A3 RSQ Mm.52109 NM_010848 1 1 17863 Myb myeloblastosis oncogene (Myb), mRNA. calcium ion transport;; DNA binding;; embryonic gut development;; G1/S transition of mitotic cell cycle;; in utero embryonic development;; nucleus;; protein binding;; regulation of gene expression;; regulation of transcription;; regulation of transcription, DNA-dependent;; regulation of transcription, DNA-dependent;; transcription;; transcription factor activity;; transcription factor activity;; transcription regulator activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription factor activity biological regulation;; cellular process;; developmental process;; establishment of localization;; localization;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; biosynthetic process;; cell cycle;; cell cycle process;; cellular metabolic process;; embryonic development;; establishment of localization;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; transport 1382.8105 1584.5236 892.2230 470.4344 673.0312 697.4835 0.027394554 1.04870 10.28816 9.23946 1340623 1450686_at chr6:5214623-5248373 6 A1 RSQ Mm.126984 NM_183308 1 1 330260 Pon2 paraoxonase 2 (Pon2), mRNA. Bisphenol A degradation CLASS Metabolism; Xenobiotics Biodegradation and Metabolism; gamma-Hexac;; gamma-Hexachlorocyclohexane degradation aryldialkylphosphatase activity;; arylesterase activity;; extracellular region;; hydrolase activity;; membrane cell;; cell part;; extracellular region cell part;; membrane catalytic activity hydrolase activity 741.0120 700.9453 783.6858 338.6490 473.2014 276.3488 0.0098859767 1.06678 9.53355 8.46677 1340636 1450699_at chr3:95018486-95030162 3 F2.1 RSQ Mm.196558 NM_009150 4 4 20341 Selenbp1 selenium binding protein 1 (Selenbp1), mRNA. cytoplasm;; membrane;; nucleus;; protein transport;; selenium binding;; transport cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding selenium binding establishment of localization;; localization establishment of localization;; establishment of protein localization;; macromolecule localization;; transport 1740.2842 982.9103 1364.5571 562.8114 361.1247 831.1518 0.040118472 1.26280 10.37341 9.11061 1340752 1450850_at chr17:6587788-6632438 17 A1 RSQ Mm.277812 NM_009510 2 2 22350 Ezr ezrin (Ezr), mRNA. Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway;; mCalpain and friends in Cell motility;; uCalpain and friends in Cell spread Leukocyte transendothelial migration;; Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cy apical part of cell;; apical plasma membrane;; binding;; cell projection;; cytoplasm;; cytoskeletal protein binding;; cytoskeleton;; establishment or maintenance of apical/basal cell polarity;; extrinsic to membrane;; membrane;; microtubule basal body;; microvillus;; plasma membrane;; protein binding;; regulation of cell shape;; uropod cell;; cell part;; organelle;; organelle part apical part of cell;; cell part;; cell projection;; cell projection part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; non-membrane-bounded organelle;; organelle part;; trailing edge binding protein binding biological regulation;; cellular process;; developmental process;; regulation of biological process anatomical structure development;; anatomical structure morphogenesis;; cellular component organization;; cellular developmental process;; establishment or maintenance of cell polarity;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process 413.0836 339.4155 374.9065 218.4987 176.7363 154.1940 0.0033448036 1.04735 8.54920 7.50185 1348888 1451239_a_at chr5:108910986-108911413 5 F UGA Mm.440571 231583 Slc26a1 Solute carrier family 26 (sulfate transporter), member 1 chloride transmembrane transporter activity;; chloride transport;; integral to membrane;; membrane;; oxalate transmembrane transporter activity;; oxalate transport;; secondary active sulfate transmembrane transporter activity;; sulfate transmembrane transporter activity;; sulfate transport;; transport;; transporter activity cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 1337.8586 1170.5417 1005.1876 500.4027 401.2787 486.8606 0.0010120783 1.33638 10.18397 8.84759 1348987 1451596_a_at chr11:116352167-116352697 11 E2 UG5 Mm.20944 20698 RP23-193A16.4 Sphk1 Sphingosine kinase 1 Phospholipids as signalling intermediaries Calcium signaling pathway;; Sphingolipid metabolism;; VEGF signaling pathway CLASS Metabolism; Lipid Metabolism; Sphingolipid metabolism [PATH:mmu0060 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; ATP binding;; blood vessel development;; brain development;; calmodulin binding;; cytoplasm;; diacylglycerol kinase activity;; DNA binding;; inflammatory response;; kinase activity;; membrane fraction;; negative regulation of apoptosis;; nucleotide binding;; positive regulation of cell proliferation;; positive regulation of fibroblast proliferation;; regulation of interleukin-1 beta production;; soluble fraction;; sphinganine kinase activity;; sphinganine kinase activity;; transferase activity cell;; cell part cell fraction;; cell part;; intracellular;; intracellular part binding;; catalytic activity nucleic acid binding;; nucleotide binding;; protein binding;; transferase activity biological regulation;; cellular process;; developmental process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; cell communication;; cell death;; cell proliferation;; cytokine production;; death;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; positive regulation of biological process;; positive regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of molecular function;; regulation of multicellular organismal process;; response to external stimulus;; response to stress 111.6269 108.0370 89.5797 62.2501 53.2187 38.0504 0.011159956 1.03311 6.68101 5.64790 1349094 1451867_x_at chrX:164380733-164648540 X F5 RSQ Mm.441810 NM_178754 2 1 11856 RP23-24O15.2 Arhgap6 Rho GTPase activating protein 6 (Arhgap6), transcript variant 2, mRNA. Rho cell motility signaling pathway actin cytoskeleton;; actin filament organization;; cytoplasm;; focal adhesion formation;; GTPase activator activity;; intracellular;; positive regulation of GTPase activity;; regulation of GTPase activity;; Rho GTPase activator activity;; SH3 domain binding;; signal transduction cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; enzyme regulator activity enzyme activator activity;; GTPase regulator activity;; protein binding biological adhesion;; biological regulation;; cellular process;; regulation of biological process actin filament-based process;; cell adhesion;; cell communication;; cellular component organization;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 1105.2744 970.9674 1080.3552 524.0301 398.5861 647.5468 0.008019323 1.03322 10.03692 9.00370 1349166 1452024_a_at chr19:46085904-46092932 19 C3 RSQ Mm.327442 NM_001113408 2 1 16825 Ldb1 LIM domain binding 1 (Ldb1), transcript variant 1, mRNA. Multi-step Regulation of Transcription by Pitx2 anterior/posterior axis specification;; cerebellar Purkinje cell differentiation;; cerebellum development;; DNA binding;; gastrulation with mouth forming second;; LIM domain binding;; LIM domain binding;; multicellular organismal development;; negative regulation of erythrocyte differentiation;; nucleus;; protein binding;; protein complex;; protein homodimerization activity;; transcription cofactor activity;; Wnt receptor signaling pathway cell;; cell part;; macromolecular complex;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; protein complex binding;; transcription regulator activity nucleic acid binding;; protein binding;; transcription cofactor activity biological regulation;; cellular process;; developmental process;; immune system process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; anatomical structure formation;; anatomical structure morphogenesis;; cell communication;; cell development;; cellular developmental process;; embryonic development;; immune system development;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; pattern specification process;; regulation of biological process;; regulation of biological quality;; regulation of cellular process;; regulation of developmental process;; regulation of homeostatic process;; regulation of immune system process;; regulation of multicellular organismal process 437.1520 273.1596 448.7705 249.6826 134.5149 160.4398 0.035200843 1.10465 8.55848 7.45382 1349168 1452026_a_at chr3:129873205-129886979 3 G3 RSQ Mm.151951 NM_183423 2 1 66350 Pla2g12a phospholipase A2, group XIIA (Pla2g12a), transcript variant 2, mRNA. alpha-Linolenic acid metabolism;; Arachidonic acid metabolism;; Ether lipid metabolism;; Fc epsilon RI signaling pathway;; Glycerophospholipid metabolism;; GnRH signaling pathway CLASS Metabolism; Lipid Metabolism; Glycerophospholipid metabolism [PATH:;; Linoleic acid metabolism;; Long-term depression;; MAPK signaling pathway;; VEGF signaling pathway calcium ion binding;; cytoplasm;; endoplasmic reticulum;; extracellular region;; Golgi apparatus;; hydrolase activity;; intracellular;; lipid catabolic process;; metal ion binding;; phospholipase A2 activity;; phospholipid metabolic process cell;; cell part;; extracellular region;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; ion binding cellular process;; metabolic process catabolic process;; cellular metabolic process;; primary metabolic process 143.4470 121.5603 261.8138 64.7627 48.2733 74.5980 0.020352084 1.43033 7.37410 5.94377 1341586 1452094_at chr10:58766732-58767261 10 B4 UGA Mm.2212 18451 P4ha1 Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide Arginine and proline metabolism CLASS Metabolism; Amino Acid Metabolism; Arginine and proline me binding;; collagen fibril organization;; endoplasmic reticulum;; iron ion binding;; L-ascorbic acid binding;; metal ion binding;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; peptidyl-proline hydroxylation to 4-hydroxy-L-proline;; procollagen-proline 4-dioxygenase activity;; procollagen-proline 4-dioxygenase activity;; protein metabolic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; oxidoreductase activity;; vitamin binding cellular process;; metabolic process cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; nitrogen compound metabolic process;; oxidation reduction;; primary metabolic process 1878.5946 1547.3079 1686.7648 701.8913 679.9120 720.2145 0.00011110607 1.27814 10.73034 9.45220 1349215 1452169_a_at chr2:91733669-91733724 2 E1 UGA Mm.314923 104418 RP23-273F8.4 Dgkz Diacylglycerol kinase zeta Glycerolipid metabolism;; Glycerophospholipid metabolism;; Phosphatidylinositol signaling system CLASS Metabolism; Lipid Metabolism; Glycerolipid metabolis activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;; cytoplasm;; diacylglycerol binding;; diacylglycerol kinase activity;; enzyme inhibitor activity;; intracellular signaling cascade;; kinase activity;; membrane;; metal ion binding;; negative regulation of Ras protein signal transduction;; nucleus;; plasma membrane;; protein binding;; transferase activity;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane-bounded organelle binding;; catalytic activity;; enzyme regulator activity enzyme inhibitor activity;; ion binding;; lipid binding;; protein binding;; transferase activity biological regulation;; cellular process;; negative regulation of biological process;; regulation of biological process cell communication;; negative regulation of biological process;; negative regulation of cellular process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 287.1686 380.2330 962.7378 83.5830 90.1839 96.0825 0.010725598 2.39379 8.88250 6.48871 1341826 1452388_at chr17:34577414-34580212 17 B1 RSQ Mm.6388 NM_010479 1 1 193740 Hspa1a heat shock protein 1A (Hspa1a), mRNA. Antigen processing and presentation CLASS Environmental Information Processing; Membrane Transpo;; MAPK signaling pathway ATP binding;; cytoplasmic part;; DNA repair;; mitochondrion;; nucleotide binding;; response to heat;; response to heat;; response to stress;; telomere maintenance cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding nucleotide binding biological regulation;; cellular process;; metabolic process;; response to stimulus cellular component organization;; cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; primary metabolic process;; regulation of biological quality;; response to abiotic stimulus;; response to stress 355.0432 213.6789 187.7572 139.7947 107.8708 59.3961 0.04468958 1.33042 7.92129 6.59087 1349293 1452514_a_at chr5:75856720-75938419 5 C3.3 RSQ Mm.247073 NM_021099 2 1 16590 Kit kit oncogene (Kit), transcript variant 2, mRNA. Melanocyte Development and Pigmentation Pathway;; Regulation of BAD phosphorylation Acute myeloid leukemia CLASS Environmental Information Processing; Signaling Molecules and Inter;; Cytokine-cytokine receptor interaction;; Hematopoietic cell lineage;; Melanogenesis ATP binding;; cell differentiation;; cell surface;; chemotaxis;; cytokine-mediated signaling pathway;; external side of plasma membrane;; germ cell development;; germ cell programmed cell death;; glycosphingolipid metabolic process;; hemopoiesis;; integral to membrane;; kinase activity;; lymphoid progenitor cell differentiation;; membrane;; myeloid leukocyte differentiation;; myeloid progenitor cell differentiation;; negative regulation of programmed cell death;; negative regulation of programmed cell death;; nucleotide binding;; peptidyl-tyrosine phosphorylation;; pigmentation;; pigmentation during development;; positive regulation of cell proliferation;; positive regulation of gene expression;; positive regulation of MAP kinase activity;; protein amino acid autophosphorylation;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein kinase cascade;; protein tyrosine kinase activity;; receptor activity;; regulation of pigmentation during development;; regulation of pigmentation during development;; response to radiation;; spermatid development;; stem cell factor receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway cell;; cell part cell part;; cell surface;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; developmental process;; immune system process;; localization;; locomotion;; metabolic process;; multicellular organismal process;; negative regulation of biological process;; pigmentation;; positive regulation of biological process;; regulation of biological process;; reproduction;; reproductive process;; response to stimulus anatomical structure development;; behavior;; cell communication;; cell death;; cell development;; cell motility;; cell motion;; cell proliferation;; cellular developmental process;; cellular metabolic process;; death;; gamete generation;; immune system development;; localization of cell;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of developmental process;; pigmentation during development;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of metabolic process;; regulation of molecular function;; reproductive process;; response to abiotic stimulus;; response to chemical stimulus;; response to external stimulus;; sexual reproduction;; taxis 150.8830 192.0146 282.5676 89.3265 73.8712 136.7982 0.046475213 1.06032 7.65494 6.59462 1349358 1452708_a_at chr17:25993888-26003449 17 A3.3 UG5 Mm.440216 66978 Luc7l Luc7 homolog (S. cerevisiae)-like metal ion binding;; negative regulation of striated muscle development;; nucleus;; protein binding;; RS domain binding;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; protein binding biological regulation;; developmental process;; multicellular organismal process;; negative regulation of biological process;; regulation of biological process anatomical structure development;; multicellular organismal development;; negative regulation of biological process;; negative regulation of developmental process;; regulation of biological process;; regulation of developmental process;; regulation of multicellular organismal process 241.6084 217.3814 229.8882 98.6330 100.3477 145.2587 0.0054678237 1.02335 7.84180 6.81845 1349430 1453497_a_at chrX:159772959-159776129 X F5 UGA Mm.3781 18700 RP23-202H24.3 Piga Phosphatidylinositol glycan anchor biosynthesis, class A Glycan structures - biosynthesis 2 CLASS Metabolism; Glycan Biosynthesis and Metabolism; Glycosy;; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis biosynthetic process;; endoplasmic reticulum;; GPI anchor biosynthetic process;; integral to membrane;; membrane;; transferase activity;; transferase activity, transferring glycosyl groups cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 145.9425 93.5459 125.0402 46.1016 27.5658 72.1542 0.033713495 1.40618 6.90104 5.49486 1349611 1454842_a_at chr13:13746799-13791194 13 A1 RSQ Mm.21686 NM_178640 1 1 97884 B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2 (B3galnt2), mRNA. acetylgalactosaminyltransferase activity;; galactosyltransferase activity;; Golgi apparatus;; integral to membrane;; membrane;; protein amino acid glycosylation;; transferase activity;; transferase activity, transferring glycosyl groups;; UDP-N-acetylgalactosamine metabolic process cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle catalytic activity transferase activity cellular process;; metabolic process biosynthetic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 186.0641 181.1869 200.8071 72.0089 81.9349 117.0252 0.0068565467 1.09782 7.56355 6.46573 1342349 1454967_at chr17:26503758-26504255 17 A3.3 UGA Mm.275414 Transcribed locus 714.4578 628.8693 661.4948 317.5430 222.0703 361.5884 0.0055334317 1.18101 9.38230 8.20130 1349719 1455696_a_at chr13:34913366-34913520 13 A3.3 UGA Mm.475929 Transcribed locus 2599.6308 1963.8381 3275.9258 937.7616 641.7865 1219.9670 0.011894396 1.50319 11.32041 9.81722 1349817 1456014_s_at chr19:7066062-7066133 19 A UGA Mm.157591 108101 Fermt3 Fermitin family homolog 3 (Drosophila) cell adhesion;; cytoplasm;; cytoskeleton;; podosome;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; non-membrane-bounded organelle;; organelle part;; protein complex binding protein binding biological adhesion;; cellular process cell adhesion 4119.2671 3478.6263 3954.8595 1279.7472 765.3927 1271.8883 0.0020162776 1.83581 11.90729 10.07149 1349897 1456307_s_at chr8:91184339-91220066 8 C3 RSQ Mm.288206 NM_001109756 4 1 11513 Adcy7 adenylate cyclase 7 (Adcy7), transcript variant 4, mRNA. Calcium signaling pathway;; Gap junction;; GnRH signaling pathway;; Melanogenesis CLASS Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mmu00230] Environ;; Purine metabolism activation of adenylate cyclase activity;; adenylate cyclase activity;; cAMP biosynthetic process;; cyclic nucleotide biosynthetic process;; integral to membrane;; intracellular signaling cascade;; lyase activity;; magnesium ion binding;; membrane;; metal ion binding;; phosphorus-oxygen lyase activity;; plasma membrane cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity cyclase activity;; ion binding;; lyase activity biological regulation;; cellular process;; metabolic process;; regulation of biological process biosynthetic process;; cell communication;; cellular metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process;; regulation of molecular function 78.0593 109.0985 131.0958 43.8124 41.9005 75.8892 0.046692605 1.00083 6.69682 5.69599 1342842 1460229_at chr5:138510338-138542181 5 G2 RSQ Mm.285609 NM_016964 1 1 50878 Stag3 stromal antigen 3 (Stag3), mRNA. cell cycle;; chromosome segregation;; female meiosis sister chromatid cohesion;; male germ cell nucleus;; male meiosis sister chromatid cohesion;; meiosis;; meiotic cohesin complex;; nucleus;; synaptonemal complex;; transverse filament cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein complex cellular process cell cycle;; cell cycle process;; cellular component organization;; chromosome segregation 343.7122 178.5183 259.7718 83.9616 84.8445 127.2905 0.015067085 1.37857 7.97536 6.59680 1370845 1428773_s_at chrX:11193695-11237013 X A1.1 RSQ Mm.196328 NM_175045 4 1 71458 RP23-451N14.1 Bcor BCL6 interacting corepressor (Bcor), transcript variant c, mRNA. chromatin modification;; negative regulation of specific transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 124.2012 102.7028 182.6019 57.3271 52.3293 66.7374 0.011189677 1.18010 7.05048 5.87037 1351076 1429351_at chr16:20011096-20041287 16 A3 RSQ Mm.392914 NM_029436 1 1 75785 Klhl24 kelch-like 24 (Drosophila) (Klhl24), mRNA. cell projection;; cytoplasm;; protein binding cell;; cell part cell part;; cell projection;; intracellular;; intracellular part binding protein binding 179.8168 94.1245 133.5824 41.6515 54.9801 86.4890 0.045767424 1.17096 7.03616 5.86519 1351137 1429438_at chrX:11193695-11237013 X A1.1 RSQ Mm.196328 NM_175045 1 1 71458 RP23-451N14.1 Bcor BCL6 interacting corepressor (Bcor), transcript variant c, mRNA. chromatin modification;; negative regulation of specific transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 218.6347 270.1266 203.2333 106.9596 112.6519 120.9437 0.0016064214 1.01401 7.83895 6.82495 1351165 1429478_at chr14:97930517-97931044 14 E2.1 UGA Mm.23503 77744 6720463M24Rik RIKEN cDNA 6720463M24 gene cell cycle;; cell division;; mitosis cellular process cell cycle;; cell cycle process;; cell division;; cellular component organization 157.4135 169.3492 210.1026 72.7849 62.0389 124.0983 0.027706812 1.10707 7.47241 6.36534 1351182 1429503_at chr5:108148639-108227335 5 F RSQ Mm.475894 NM_026062 1 1 67266 2900024C23Rik RIKEN cDNA 2900024C23 gene (2900024C23Rik), mRNA. integral to membrane;; membrane;; protein binding cell;; cell part cell part;; membrane;; membrane part binding protein binding 745.0343 767.2430 782.1593 258.8558 251.3003 590.9157 0.043448923 1.17998 9.57867 8.39869 1351188 1429509_at chr11:101978719-101979182 11 D UGA Mm.392770 Transcribed locus 688.0117 854.6906 750.8793 180.9209 200.4299 266.4984 0.00064274184 1.83794 9.57266 7.73472 1351325 1429700_at RSQ XM_993996 7 6 73176 3110040M04Rik PREDICTED: RIKEN cDNA 3110040M04 gene (3110040M04Rik), mRNA. 648.4821 714.9150 784.2526 241.4775 238.6438 361.8261 0.0029495331 1.37470 9.47924 8.10454 1351378 1429778_at chr2:4937913-4981210 2 A1 RSQ Mm.116942 NM_181848 1 1 71648 RP23-379M5.2 Optn optineurin (Optn), mRNA. cellular protein localization;; cytoplasm;; Golgi apparatus;; perinuclear region of cytoplasm;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding cellular process;; localization cellular localization;; macromolecule localization 50.6790 76.2156 61.3739 28.2200 24.6632 29.4537 0.0032368216 1.17719 5.95163 4.77444 1351662 1430135_at chr8:87812480-87812919 8 C3 UGA Mm.437155 Transcribed locus 255.2009 396.9541 316.1797 101.6759 121.4979 170.1787 0.010085858 1.30980 8.31097 7.00118 1352068 1430653_at chr6:72305372-72305843 6 C1 UGA Mm.442925 Transcribed locus 223.6712 199.0009 213.3808 48.3890 46.4392 46.8325 2.0206738e-06 2.16528 7.72638 5.56111 1371133 1433453_a_at chr2:103367148-103519262 2 E2 RSQ Mm.35850 NM_178890 1 1 99382 RP23-338B23.1 Abtb2 ankyrin repeat and BTB (POZ) domain containing 2 (Abtb2), mRNA. DNA binding;; protein binding binding nucleic acid binding;; protein binding 94.8910 110.1221 83.5934 46.9415 42.2684 54.8833 0.0032274598 1.00129 6.57883 5.57753 1354152 1433466_at chr7:126882583-126885197 7 F3 RSQ Mm.284102 NM_178901 1 1 101602 AI467606 expressed sequence AI467606 (AI467606), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 184.4125 185.7297 194.9049 54.0549 54.5558 132.4950 0.033646437 1.36489 7.55683 6.19194 1354201 1433610_at chr1:132567817-132572167 1 E4 RSQ Mm.268547 NM_177604 1 1 212439 AA986860 expressed sequence AA986860 (AA986860), mRNA. cytoplasm;; receptor activity cell;; cell part cell part;; intracellular;; intracellular part molecular transducer activity signal transducer activity 104.4402 94.7302 143.0011 44.8185 78.1440 49.0903 0.02967822 1.01357 6.81072 5.79715 1354420 1434026_at chr3:90025407-90049435 3 F1 RSQ Mm.30455 NM_001081182 1 1 54667 Atp8b2 ATPase, class I, type 8B, member 2 (Atp8b2), mRNA. ATP binding;; ATP biosynthetic process;; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;; catalytic activity;; hydrolase activity;; integral to membrane;; magnesium ion binding;; membrane;; metabolic process;; metal ion binding;; nucleotide binding;; phospholipid transport;; phospholipid-translocating ATPase activity;; protein binding cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; transporter activity hydrolase activity;; ion binding;; nucleotide binding;; protein binding;; substrate-specific transporter activity;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; metabolic process cellular metabolic process;; establishment of localization;; primary metabolic process;; transport 1241.0951 845.9552 1442.0005 319.8509 490.5284 698.2067 0.033788722 1.26291 10.16523 8.90232 1354595 1434376_at chr2:102611979-102702504 2 E2 RSQ Mm.423621 NM_001039151 3 1 12505 RP23-203N8.3 Cd44 CD44 antigen (Cd44), transcript variant 3, mRNA. Adhesion Molecules on Lymphocyte;; Monocyte and its Surface Molecules;; Neutrophil and Its Surface Molecules ECM-receptor interaction;; Hematopoietic cell lineage CLASS Environmental Information Processing; Signaling Molecules and I basolateral plasma membrane;; binding;; cell adhesion;; cell surface;; external side of plasma membrane;; healing during inflammatory response;; hyaluronic acid binding;; hyaluronic acid binding;; integral to membrane;; membrane;; plasma membrane;; protein binding;; receptor activity;; ureteric bud branching cell;; cell part cell part;; cell surface;; membrane;; membrane part binding;; molecular transducer activity carbohydrate binding;; pattern binding;; protein binding;; signal transducer activity biological adhesion;; cellular process;; developmental process;; multicellular organismal process;; response to stimulus anatomical structure development;; anatomical structure morphogenesis;; cell adhesion;; multicellular organismal development;; response to external stimulus;; response to stress 323.5900 571.7248 395.0474 236.6572 176.5465 193.9516 0.017481918 1.05766 8.70769 7.65004 1371205 1434895_s_at chr12:112276265-112355863 12 F1 RSQ Mm.313076 NM_011625 1 1 21981 Ppp1r13b protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b), mRNA. apoptosis;; cytoplasm;; nucleus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle cellular process;; developmental process cell death;; death 123.1543 237.1136 213.8950 59.6747 85.1391 112.1516 0.043245127 1.15147 7.52484 6.37337 1355130 1435343_at chr1:80380091-80494620 1 C4 RSQ Mm.133473 NM_175291 1 1 210293 Dock10 dedicator of cytokinesis 10 (Dock10), mRNA. GTP binding;; GTPase binding;; guanyl-nucleotide exchange factor activity;; Rho GTPase binding;; Rho guanyl-nucleotide exchange factor activity binding;; enzyme regulator activity GTPase regulator activity;; nucleotide binding;; protein binding 491.4980 633.4120 756.4919 210.6530 238.1223 337.4632 0.0096443799 1.26612 9.27041 8.00429 1355345 1435679_at chr2:4937913-4981210 2 A1 RSQ Mm.116942 NM_181848 1 1 71648 RP23-379M5.2 Optn optineurin (Optn), mRNA. cellular protein localization;; cytoplasm;; Golgi apparatus;; perinuclear region of cytoplasm;; protein binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding protein binding cellular process;; localization cellular localization;; macromolecule localization 115.1609 205.5185 212.9453 55.3965 51.9525 41.2543 0.0046219416 1.80255 7.42166 5.61911 1355587 1436080_at UGA Mm.475160 Transcribed locus 568.9507 622.8350 390.8538 139.8324 139.7467 208.8564 0.0038678527 1.69492 9.01512 7.32020 1355840 1436456_at chr13:113781653-113853776 13 D2.2 RSQ Mm.259799 NM_178746 1 1 268706 Slc38a9 solute carrier family 38, member 9 (Slc38a9), mRNA. amino acid transport;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; transport cell;; cell part cell part;; membrane;; membrane part binding ion binding establishment of localization;; localization establishment of localization;; transport 149.4396 125.6884 202.6887 63.6816 55.7691 53.2573 0.0025980943 1.44371 7.28675 5.84304 1355878 1436514_at chrX:48296127-48296591 X A5 UGA Mm.472188 Transcribed locus 176.0414 188.1152 155.0007 85.1263 55.0238 129.5093 0.048446065 1.02698 7.43046 6.40348 1355898 1436540_at chr13:48547491-48547943 13 A5 UGA Mm.26586 Transcribed locus 338.4682 209.1878 202.5995 130.8608 72.5292 105.4918 0.020694458 1.28022 7.92467 6.64446 1356044 1436796_at chr18:35682630-35683727 18 B2 UGA Mm.215034 17184 Matr3 Matrin 3 RNA polymerase III transcription intracellular;; metal ion binding;; nucleic acid binding;; nucleotide binding;; nucleus;; RNA binding;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding ion binding;; nucleic acid binding;; nucleotide binding 422.6472 266.7379 206.7592 108.7010 114.3585 145.6015 0.020137337 1.22896 8.15813 6.92917 1371306 1437073_x_at chr14:74494294-74494508 14 D3 UGA Mm.473985 Transcribed locus 72.7973 78.4583 99.9947 32.2048 43.1938 40.6761 0.0041891431 1.11179 6.37448 5.26269 1356179 1437106_at chr6:120347153-120410193 6 F1 RSQ XM_979596 3 1 214899 Jarid1a PREDICTED: jumonji, AT rich interactive domain 1A (Rbp2 like) (Jarid1a), mRNA. chromatin modification;; DNA binding;; intracellular;; iron ion binding;; metal ion binding;; multicellular organismal development;; nucleus;; oxidation reduction;; oxidoreductase activity;; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; zinc ion binding cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity ion binding;; nucleic acid binding;; oxidoreductase activity;; protein binding biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; oxidation reduction;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 1132.7221 1227.0923 1388.0378 436.3188 316.4465 813.0457 0.028641972 1.36773 10.28181 8.91408 1356589 1437891_at chr10:116474236-116552584 10 D2 RSQ Mm.135965 NM_177798 1 1 327826 Frs2 fibroblast growth factor receptor substrate 2 (Frs2), mRNA. activation of MAPK activity;; cytoplasm;; determination of anterior/posterior axis, embryo;; fibroblast growth factor receptor signaling pathway;; forebrain development;; gastrulation with mouth forming second;; induction of an organ;; insulin receptor binding;; membrane;; neuroblast proliferation;; neuroblast proliferation;; optic placode formation involved in camera-type eye;; plasma membrane;; protein binding;; transmembrane receptor protein tyrosine kinase docking protein activity;; transmembrane receptor protein tyrosine kinase signaling pathway cell;; cell part cell part;; intracellular;; intracellular part;; membrane binding;; molecular transducer activity protein binding;; signal transducer activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process anatomical structure development;; anatomical structure formation;; anatomical structure morphogenesis;; cell communication;; cell development;; cell fate commitment;; cell proliferation;; cellular developmental process;; cellular metabolic process;; embryonic development;; macromolecule metabolic process;; multicellular organismal development;; pattern specification process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of molecular function 1157.7045 1696.3350 960.1361 773.8266 517.7429 294.1526 0.04741471 1.33332 10.27078 8.93746 1356779 1438239_at chrX:165319590-165320119 X F5 UGA Mm.467605 Clone MEX2B-5 Mid1 mRNA, partial sequence 145.0385 147.1255 224.3325 54.5673 62.2186 99.3466 0.018750592 1.27568 7.39690 6.12121 1356785 1438253_at chr5:114202786-114203276 5 F UGA Mm.389682 231637 Ssh1 Slingshot homolog 1 (Drosophila) Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cy actin binding;; cytoplasm;; cytoskeleton;; dephosphorylation;; hydrolase activity;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 3095.5425 3497.3266 4742.4540 1478.6267 1659.4137 1832.7456 0.0045399334 1.17105 11.85981 10.68876 1357019 1438688_at chr17:23530808-23552363 17 A3.3 RSQ Mm.5222 NM_175229 2 2 75956 Srrm2 serine/arginine repetitive matrix 2 (Srrm2), mRNA. mRNA processing;; nucleus;; RNA splicing;; spliceosome cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; organelle part;; ribonucleoprotein complex cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 38.3196 65.3287 36.8999 19.9238 13.6612 29.4684 0.047687065 1.17522 5.49840 4.32318 1357106 1438821_at chr1:161109814-161110080 1 H1 UGA Mm.451705 Transcribed locus 461.5087 811.9415 513.9043 226.6064 292.9365 252.8720 0.012497335 1.17335 9.17360 8.00025 1357113 1438831_at chr11:98042190-98042685 11 D UGA Mm.473748 Transcribed locus 130.7484 104.7424 110.5964 54.7576 56.8324 50.3202 0.00056735211 1.09127 6.84350 5.75223 1357195 1439034_at chr7:126924977-126925308 7 F3 UGA Mm.283714 20737 Spn Sialophorin Cell adhesion molecules (CAMs) CLASS Environmental Information Processing; Signaling Molecules a bacterial binding;; bacterial binding;; basement membrane;; cell surface receptor linked signal transduction;; defense response to bacterium;; defense response to bacterium;; external side of plasma membrane;; extracellular space;; induction of apoptosis by extracellular signals;; integral to membrane;; integral to plasma membrane;; membrane;; negative regulation of cell adhesion;; negative regulation of cell adhesion;; negative regulation of T cell activation;; negative regulation of T cell proliferation;; negative regulation of type IV hypersensitivity;; negative thymic T cell selection;; positive regulation of T cell proliferation;; positive regulation of tumor necrosis factor biosynthetic process;; positive regulation of tumor necrosis factor biosynthetic process;; protein binding;; regulation of defense response to virus;; regulation of immune response;; response to protozoan;; T cell costimulation;; uropod cell;; cell part;; extracellular region;; extracellular region part cell part;; cell projection;; cell surface;; extracellular matrix;; extracellular matrix part;; extracellular region part;; extracellular space;; membrane;; membrane part;; trailing edge binding bacterial binding;; protein binding biological adhesion;; biological regulation;; cellular process;; developmental process;; immune system process;; metabolic process;; multi-organism process;; multicellular organismal process;; negative regulation of biological process;; positive regulation of biological process;; regulation of biological process;; response to stimulus anatomical structure development;; biosynthetic process;; cell activation;; cell adhesion;; cell communication;; cell death;; cell proliferation;; cellular developmental process;; cellular metabolic process;; cytokine production;; death;; immune effector process;; immune response;; immune system development;; leukocyte activation;; lymphocyte costimulation;; macromolecule metabolic process;; multicellular organismal development;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of immune system process;; negative regulation of response to stimulus;; positive regulation of biological process;; positive regulation of cellular process;; positive regulation of developmental process;; positive regulation of immune system process;; positive regulation of metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of developmental process;; regulation of immune system process;; regulation of metabolic process;; regulation of multi-organism process;; regulation of multicellular organismal process;; regulation of response to stimulus;; response to biotic stimulus;; response to external stimulus;; response to other organism;; response to stress;; T cell selection 140.6924 151.4968 96.5166 39.1751 49.8789 52.1941 0.0037708656 1.44474 6.99075 5.54601 1371445 1439353_x_at chr3:121194030-121255339 3 G1 RSQ Mm.26088 NM_178936 1 1 99887 Tmem56 transmembrane protein 56 (Tmem56), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 58.6012 34.2945 36.9107 14.7763 23.4157 19.6463 0.020657734 1.14931 5.39291 4.24360 1357586 1439638_at chr13:104945983-104946482 13 D1 UGA Mm.442245 Transcribed locus 235.5887 312.6555 200.4186 78.7682 112.7932 129.0228 0.012284514 1.22896 7.93848 6.70952 1357922 1440011_at chr15:53155943-53156476 15 C IPA Mus musculus 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630005I06 product:hypothetical protein, full insert sequence. 200.2575 217.5363 363.8004 84.3226 110.0408 150.2696 0.031841705 1.16889 7.97261 6.80372 1358098 1440222_at chr16:90110432-90110895 16 C3.3 UGA Mm.466779 Transcribed locus, weakly similar to NP_001021956.1 SOD (superoxide dismutase) family member (sod-1) [Caenorhabditis elegans] 52.9295 82.4274 82.4647 21.9527 20.0101 18.1947 0.0012841032 1.83078 6.15225 4.32148 1358342 1440475_at UGA Mm.475160 Transcribed locus 182.3870 357.9680 216.5114 92.2566 117.0519 100.1432 0.016090182 1.23611 7.91762 6.68150 1358669 1440851_at chr11:30829827-30830350 11 A4 IPA 4933407N01Rik RIKEN cDNA 4933407N01 gene 449.6805 466.7154 496.4642 189.3587 222.6475 265.0968 0.0018316834 1.07358 8.87823 7.80466 1358769 1440966_at chr2:60048207-60048736 2 C1.1 UGA Mm.260635 57438 RP23-10L17.1 March7 Membrane-associated ring finger (C3HC4) 7 ligase activity;; metal ion binding;; protein binding;; ubiquitin-dependent protein catabolic process;; zinc ion binding binding;; catalytic activity ion binding;; ligase activity;; protein binding cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 139.5327 118.7511 196.4829 89.5420 52.6122 82.9352 0.03373276 1.01960 7.21151 6.19191 1359366 1441604_at chr14:73476670-73477136 14 D3 UG5 Mm.38055 13885 Esd Esterase D/formylglutathione hydrolase carboxylesterase activity;; cytoplasm;; cytoplasmic membrane-bounded vesicle;; cytoplasmic vesicle;; hydrolase activity;; hydrolase activity, acting on ester bonds;; S-formylglutathione hydrolase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; vesicle catalytic activity hydrolase activity 164.0316 332.2201 328.5666 69.0654 117.5938 115.4695 0.027947973 1.41831 8.03129 6.61298 1359582 1441848_at chr16:8562953-8563069 16 A1 IPA ESTs 907.8475 880.4037 819.5238 414.0635 325.2947 592.6845 0.016595258 1.01218 9.76232 8.75014 1359645 1442000_at chr12:4888269-4888890 12 A1.1 UGA Mm.154078 432628 Gm1964 Gene model 1964, (NCBI) integral to membrane;; membrane;; transport cell;; cell part cell part;; membrane;; membrane part establishment of localization;; localization establishment of localization;; transport 148.4577 204.0080 207.8034 76.0049 59.8913 89.2509 0.0045708768 1.31779 7.52849 6.21070 1359935 1442302_at chr11:32130715-32131174 11 A4 UGA Mm.475096 268395 RP23-177M10.5 Mpg N-methylpurine-DNA glycosylase Base excision repair CLASS Genetic Information Processing; Replication and Repair; Base excision alkylbase DNA N-glycosylase activity;; alkylbase DNA N-glycosylase activity;; base-excision repair;; DNA binding;; DNA repair;; hydrolase activity;; nucleus;; response to DNA damage stimulus cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; catalytic activity hydrolase activity;; nucleic acid binding cellular process;; metabolic process;; response to stimulus cellular metabolic process;; cellular response to stimulus;; macromolecule metabolic process;; primary metabolic process;; response to stress 22.1724 40.4594 41.0921 12.2442 21.0140 13.3099 0.039713176 1.14272 5.05663 3.91391 1360371 1442775_at chr15:81217417-81217714 15 E1 IPA ESTs 184.6858 299.0118 242.9763 123.2223 128.2001 72.3763 0.023782349 1.18428 7.89255 6.70827 1361186 1443657_at chr3:84538803-84539129 3 F1 UG5 Mm.331107 229474 Fhdc1 FH2 domain containing 1 actin binding;; actin cytoskeleton organization;; cellular component organization binding protein binding cellular process actin filament-based process;; cellular component organization 140.9775 229.1202 140.7945 47.2866 50.2647 80.4847 0.010627473 1.52375 7.37224 5.84849 1361312 1443858_at chr7:104212668-104213126 7 E3 UGA Mm.440241 Transcribed locus 127.3191 71.6001 89.4547 37.6039 42.1522 45.5793 0.010231694 1.16554 6.54576 5.38022 1361324 1443870_at chr14:117366438-117366990 14 E4 UGA Mm.40537 239273 Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 ATP binding;; membrane fraction;; multidrug efflux pump activity;; multidrug transport;; nucleotide binding;; plasma membrane;; platelet dense granule membrane cell;; cell part;; organelle;; organelle part cell fraction;; cell part;; endomembrane system;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane-bounded organelle;; organelle membrane;; organelle part;; vesicle binding;; transporter activity drug transporter activity;; nucleotide binding;; transmembrane transporter activity cellular process;; establishment of localization;; localization;; response to stimulus establishment of localization;; response to chemical stimulus;; transmembrane transport;; transport 97.9429 139.6751 93.4281 46.2303 58.7297 46.7903 0.0066570855 1.11022 6.76186 5.65164 1361633 1444195_at chr6:71352336-71352853 6 C1 UGA Mm.414330 Transcribed locus 181.4281 170.2018 181.6284 74.4348 65.8360 67.8374 2.5099172e-05 1.35883 7.47307 6.11424 1362192 1444769_at chr9:72260100-72260551 9 D UG5 Mm.14485 21778 Tex9 Testis expressed gene 9 31.9427 29.2821 38.8508 13.2889 14.9215 14.8405 0.0007975863 1.20877 5.04974 3.84098 1363686 1446318_at chr4:53577718-53578222 4 B2 IPA Mus musculus 10 days neonate cortex cDNA, RIKEN full-length enriched library, clone:A830082F08 product:unknown EST, full insert sequence. 2371.5091 2603.3076 1933.6416 1336.9262 1388.8827 723.4259 0.033478971 1.05057 11.15827 10.10770 1371917 1447100_s_at chr3:127861763-127862020 3 G2 UG5 Mm.394052 Transcribed locus 187.4976 170.6022 209.5575 67.4692 59.4871 130.3716 0.027419643 1.22642 7.55881 6.33238 1364562 1447227_at chr1:45866237-45866599 1 C1.1 UGA Mm.459542 Transcribed locus 261.7387 413.7440 314.5890 104.7600 115.2262 192.8561 0.018110919 1.29042 8.34063 7.05022 1364592 1447263_at chr10:93310250-93310545 10 C2 UGA Mm.450117 Transcribed locus 385.0283 445.7809 408.4524 153.1381 138.8780 184.2911 0.0004992119 1.38694 8.68768 7.30074 1372079 1447784_x_at chr13:113852460-113852585 13 D2.2 UGA Mm.259799 268706 Slc38a9 Solute carrier family 38, member 9 amino acid transport;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; transport cell;; cell part cell part;; membrane;; membrane part binding ion binding establishment of localization;; localization establishment of localization;; transport 161.4591 261.1823 161.0078 59.2219 62.2429 44.5327 0.0029335079 1.79008 7.56498 5.77490 1372136 1447854_s_at chr3:96306525-96309143 3 F2.1 RSQ Mm.439791 NM_178214 1 1 319190 Hist2h2be histone cluster 2, H2be (Hist2h2be), mRNA. Systemic lupus erythematosus CLASS Human Diseases; Immune Disorders; Systemic lupus erythematosu chromosome;; DNA binding;; nucleosome;; nucleosome assembly;; nucleus;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein-DNA complex binding nucleic acid binding;; protein binding cellular process cellular component organization 636.1885 589.5246 627.8419 304.3370 224.9117 255.6100 0.00067169744 1.25015 9.27033 8.02018 1364989 1447936_at chr11:62419084-62421004 11 B2 RSQ Mm.270874 XM_001479267 2 1 69221 2410006H16Rik PREDICTED: RIKEN cDNA 2410006H16 gene (2410006H16Rik), mRNA. 161.6355 141.7397 203.6082 60.1101 83.2751 89.7122 0.0085949318 1.12559 7.38445 6.25886 1365068 1452717_at chr3:109295949-109296481 3 F3 UGA Mm.33574 229731 DN-250O19.1 Slc25a24 Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 binding;; calcium ion binding;; integral to membrane;; membrane;; mitochondrial inner membrane;; mitochondrial transport;; mitochondrion;; transport cell;; cell part;; envelope;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane;; membrane part;; membrane-bounded organelle;; organelle envelope;; organelle membrane;; organelle part binding ion binding cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; transport 450.1522 329.9288 410.5634 171.7330 150.3765 288.1941 0.032760798 1.01146 8.62058 7.60912 1365122 1452841_at chr7:100152361-100152913 7 E2 UGA Mm.440524 70974 Pgm2l1 Phosphoglucomutase 2-like 1 carbohydrate metabolic process;; glucose metabolic process;; glucose-1,6-bisphosphate synthase activity;; intramolecular transferase activity, phosphotransferases;; isomerase activity;; magnesium ion binding;; transferase activity binding;; catalytic activity ion binding;; isomerase activity;; transferase activity cellular process;; metabolic process cellular metabolic process;; primary metabolic process 185.7415 172.1661 182.3033 64.5409 82.2336 107.9203 0.0067533742 1.11580 7.49167 6.37587 1365166 1452910_at chrX:11193695-11237013 X A1.1 RSQ Mm.196328 NM_175045 4 1 71458 RP23-451N14.1 Bcor BCL6 interacting corepressor (Bcor), transcript variant c, mRNA. chromatin modification;; negative regulation of specific transcription from RNA polymerase II promoter;; nucleus;; protein binding;; regulation of transcription, DNA-dependent;; transcription;; transcription corepressor activity;; transcription repressor activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle binding;; transcription regulator activity protein binding;; transcription cofactor activity;; transcription repressor activity biological regulation;; cellular process;; metabolic process;; negative regulation of biological process;; regulation of biological process biosynthetic process;; cellular component organization;; cellular metabolic process;; macromolecule metabolic process;; negative regulation of biological process;; negative regulation of cellular process;; negative regulation of metabolic process;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; regulation of metabolic process 372.3571 356.0209 400.7356 105.6455 104.1479 227.3346 0.01731445 1.46954 8.55429 7.08475 1365169 1452914_at chr5:150860251-150860820 5 G3 UGA Mm.279932 100637 N4bp2l1 NEDD4 binding protein 2-like 1 792.0872 558.4094 783.8923 315.4174 286.8379 420.1356 0.010498399 1.06309 9.45640 8.39331 1365218 1452982_at chr7:67825769-68107180 7 C RSQ Mm.275742 NM_010513 1 1 16001 Igf1r insulin-like growth factor I receptor (Igf1r), mRNA. Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK);; Erk1/Erk2 Mapk Signaling pathway;; IGF-1 Signaling Pathway;; Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation;; Regulation of BAD phosphorylation;; Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway;; Telomeres, Telomerase, Cellular Aging, and Immortality;; The IGF-1 Receptor and Longevity Adherens junction;; Colorectal cancer;; Focal adhesion;; Glioma;; Long-term depression;; Melanoma CLASS Cellular Processes; Cell Communication; Focal adhesion [PATH:mmu04510] Cellular P;; Prostate cancer ATP binding;; brain development;; insulin-like growth factor binding;; insulin-like growth factor receptor signaling pathway;; integral to membrane;; kinase activity;; male sex determination;; mammary gland development;; membrane;; nucleotide binding;; organ morphogenesis;; protein amino acid phosphorylation;; protein binding;; protein kinase activity;; protein tyrosine kinase activity;; receptor activity;; transferase activity;; transmembrane receptor protein tyrosine kinase activity;; transmembrane receptor protein tyrosine kinase signaling pathway cell;; cell part cell part;; membrane;; membrane part binding;; catalytic activity;; molecular transducer activity nucleotide binding;; protein binding;; signal transducer activity;; transferase activity biological regulation;; cellular process;; developmental process;; metabolic process;; multicellular organismal process;; regulation of biological process;; reproduction;; reproductive process anatomical structure development;; anatomical structure morphogenesis;; cell communication;; cellular metabolic process;; macromolecule metabolic process;; multicellular organismal development;; primary metabolic process;; regulation of biological process;; regulation of cellular process;; reproductive developmental process;; reproductive process 150.6503 181.4288 166.3734 66.5213 71.1852 108.1637 0.010701075 1.05009 7.37220 6.32211 1365529 1453416_at chr10:88838692-88839207 10 C2 UGA Mm.11982 237436 Gas2l3 Growth arrest-specific 2 like 3 cell cycle arrest cellular process cell cycle;; cell cycle process 1176.9024 1396.9578 1964.7129 602.2464 923.8567 448.0578 0.029832182 1.23189 10.52965 9.29776 1372338 1454757_s_at chr12:103835260-103841257 12 E RSQ Mm.2121 NM_194069 5 1 52668 D12Ertd647e DNA segment, Chr 12, ERATO Doi 647, expressed (D12Ertd647e), transcript variant 5, mRNA. 576.3817 356.5039 471.7536 219.4532 152.7194 269.6287 0.021819251 1.14107 8.84351 7.70245 1366616 1454996_at chr8:122448008-122448541 8 E1 UGA Mm.36756 72552 Hsdl1 Hydroxysteroid dehydrogenase like 1 binding;; catalytic activity;; metabolic process;; oxidoreductase activity binding;; catalytic activity oxidoreductase activity metabolic process 200.7885 273.2257 188.5308 102.5984 84.7696 62.1103 0.0061065671 1.41968 7.76738 6.34770 1366670 1455095_at chr3:96306525-96309143 3 F2.1 RSQ Mm.439791 NM_178214 1 1 319190 Hist2h2be histone cluster 2, H2be (Hist2h2be), mRNA. Systemic lupus erythematosus CLASS Human Diseases; Immune Disorders; Systemic lupus erythematosu chromosome;; DNA binding;; nucleosome;; nucleosome assembly;; nucleus;; protein binding cell;; cell part;; macromolecular complex;; organelle;; organelle part cell part;; intracellular;; intracellular organelle;; intracellular organelle part;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle;; organelle part;; protein-DNA complex binding nucleic acid binding;; protein binding cellular process cellular component organization 257.2428 314.7929 270.6292 120.4591 112.2920 140.1536 0.00079257606 1.17701 8.12847 6.95146 1366999 1455612_at chr13:113859073-113859569 13 D2.2 UGA Mm.40834 Transcribed locus 925.6574 1287.0046 1249.9532 429.1109 388.6015 556.7211 0.0035349939 1.33454 10.15726 8.82272 1372382 1455854_a_at chr5:114200777-114200870 5 F UGA Mm.389682 231637 Ssh1 Slingshot homolog 1 (Drosophila) Regulation of actin cytoskeleton CLASS Cellular Processes; Cell Motility; Regulation of actin cy actin binding;; cytoplasm;; cytoskeleton;; dephosphorylation;; hydrolase activity;; phosphatase activity;; phosphoprotein phosphatase activity;; protein amino acid dephosphorylation;; protein tyrosine phosphatase activity;; protein tyrosine/serine/threonine phosphatase activity cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; non-membrane-bounded organelle binding;; catalytic activity hydrolase activity;; protein binding cellular process;; metabolic process cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 496.1223 352.9157 370.1258 215.4882 186.6195 190.2951 0.0035270176 1.02736 8.64987 7.62251 1367246 1456111_at chr9:48151281-48151811 9 A5.3 UGA Mm.325522 244853 D930028F11Rik RIKEN cDNA D930028F11 gene extracellular region extracellular region 87.3575 130.1352 167.4229 39.3785 36.7987 44.9886 0.0047724112 1.62256 6.95336 5.33080 1367278 1456164_at RSQ XM_001001227 2 1 100382 AW011738 PREDICTED: expressed sequence AW011738 (AW011738), mRNA. 41.7003 50.3769 42.9074 15.6893 21.4198 25.6097 0.0071889593 1.12954 5.48661 4.35707 1367300 1456207_at chrX:71665364-71665936 X A7.3 UGA Mm.440653 Transcribed locus 1474.3705 1866.3168 1113.4548 544.8488 663.4469 734.7266 0.0092578972 1.17603 10.50423 9.32820 1367371 1456338_at chr13:113781653-113853776 13 D2.2 RSQ Mm.259799 NM_178746 1 1 268706 Slc38a9 solute carrier family 38, member 9 (Slc38a9), mRNA. amino acid transport;; integral to membrane;; ion transport;; membrane;; sodium ion binding;; sodium ion transport;; transport cell;; cell part cell part;; membrane;; membrane part binding ion binding establishment of localization;; localization establishment of localization;; transport 759.2910 572.4117 652.1603 267.8677 282.3896 361.1751 0.0031764776 1.12501 9.35950 8.23449 1372409 1456378_s_at chr11:97904844-97904920 11 D UGA Mm.218350 72194 RP23-309H19.11 Fbxl20 F-box and leucine-rich repeat protein 20 cytoplasm;; protein binding;; ubiquitin-dependent protein catabolic process cell;; cell part cell part;; intracellular;; intracellular part binding protein binding cellular process;; metabolic process catabolic process;; cellular metabolic process;; macromolecule metabolic process;; primary metabolic process 295.5357 304.4636 366.9845 132.8240 103.1198 171.6903 0.00555895 1.27056 8.32563 7.05507 1367514 1456607_at chr1:9705857-9706300 1 A2 UGA Mm.440951 Transcribed locus 232.2524 217.4365 201.6698 82.3665 105.6478 88.7757 0.00052010401 1.24022 7.75995 6.51973 1367525 1456634_at chr2:156701881-156774321 2 H1 RSQ Mm.79466 XM_283804 1 1 320706 RP23-430P1.3 9830001H06Rik PREDICTED: RIKEN cDNA 9830001H06 gene (9830001H06Rik), mRNA. 235.7554 156.1778 169.8955 49.0242 45.9938 75.6830 0.0039225293 1.73200 7.52557 5.79356 1367581 1456718_at chr3:121194030-121255339 3 G1 RSQ Mm.26088 NM_178936 1 1 99887 Tmem56 transmembrane protein 56 (Tmem56), mRNA. integral to membrane;; membrane cell;; cell part cell part;; membrane;; membrane part 88.6480 138.1077 127.3040 41.3821 53.2146 79.9457 0.036604447 1.04872 6.85727 5.80854 1368061 1457264_at chr15:66453305-66453646 15 D2 UGA Mm.267473 239510 Phf20l1 PHD finger protein 20-like 1 metal ion binding;; nucleic acid binding;; zinc ion binding binding ion binding;; nucleic acid binding 202.6716 322.9145 326.5901 110.2895 158.9259 113.5619 0.015662107 1.14155 8.11645 6.97490 1368202 1457416_at chr10:93306310-93306752 10 C2 UG5 Mm.443513 Transcribed locus 76.0285 124.2292 144.6640 43.5251 55.6757 57.5780 0.023432602 1.09723 6.79396 5.69673 1368357 1457583_at chr3:153341920-153342314 3 H3 UGA Mm.451194 Transcribed locus 643.4869 708.5833 586.7124 311.7029 225.4582 393.1119 0.011271626 1.09184 9.33169 8.23985 1368648 1457933_at chr12:4898629-4899121 12 A1.1 UGA Mm.154078 432628 Gm1964 Gene model 1964, (NCBI) integral to membrane;; membrane;; transport cell;; cell part cell part;; membrane;; membrane part establishment of localization;; localization establishment of localization;; transport 613.1114 822.7056 607.9272 233.0662 295.7992 499.2276 0.041393657 1.05179 9.39733 8.34554 1368906 1458203_at chr18:67619494-67619980 18 E1 UG5 Mm.208723 68166 Spire1 Spire homolog 1 (Drosophila) actin binding;; cytoplasm;; cytoskeleton;; Golgi apparatus;; Golgi vesicle transport;; transport cell;; cell part;; organelle cell part;; intracellular;; intracellular organelle;; intracellular part;; membrane-bounded organelle;; non-membrane-bounded organelle binding protein binding cellular process;; establishment of localization;; localization cellular localization;; establishment of localization;; establishment of localization in cell;; transport;; vesicle-mediated transport 238.5912 271.1422 468.4257 94.1174 124.3720 165.7192 0.025443069 1.32182 8.28433 6.96250 1372530 1458297_s_at chr1:122302260-122321630 1 E2.3 UGA Mm.1856 17167 Marco Macrophage receptor with collagenous structure integral to membrane;; membrane;; receptor activity;; scavenger receptor activity cell;; cell part cell part;; membrane;; membrane part molecular transducer activity signal transducer activity 139.2995 89.9021 52.1969 22.5812 30.7747 19.7832 0.014645692 1.85710 6.43941 4.58231 1372536 1458327_x_at chr5:108910882-108911120 5 F UG5 Mm.440571 231583 Slc26a1 Solute carrier family 26 (sulfate transporter), member 1 chloride transmembrane transporter activity;; chloride transport;; integral to membrane;; membrane;; oxalate transmembrane transporter activity;; oxalate transport;; secondary active sulfate transmembrane transporter activity;; sulfate transmembrane transporter activity;; sulfate transport;; transport;; transporter activity cell;; cell part cell part;; membrane;; membrane part transporter activity substrate-specific transporter activity;; transmembrane transporter activity establishment of localization;; localization establishment of localization;; transport 271.9610 216.6854 339.6939 74.9426 133.9254 62.1972 0.012029968 1.66768 8.08494 6.41726 1372658 1459860_x_at chr3:84249692-84249730 3 F1 UGA Mm.44876 80890 Trim2 Tripartite motif-containing 2 cytoplasm;; intracellular;; metal ion binding;; myosin binding;; protein binding;; zinc ion binding cell;; cell part cell part;; intracellular;; intracellular part binding ion binding;; protein binding 252.2002 286.7983 290.2951 95.2991 147.3987 136.6499 0.0049251645 1.15046 8.10790 6.95744 1370547 1460096_at chr8:13161358-13161664 8 A1.1 IPA Mm.16716 Lamp1 Lysosomal-associated membrane protein 1 56.2577 42.9705 55.4240 22.6289 24.8456 22.7231 0.0010692404 1.13020 5.67723 4.54703 1372696 1460116_s_at chr2:116873330-116873614 2 E5 UG5 Mm.395506 Transcribed locus 630.0234 579.9112 588.8859 220.3093 157.1802 425.6379 0.038270649 1.28922 9.22693 7.93771 1370709 1460577_at chr13:94530925-94531448 13 C3 UGA Mm.100273 Transcribed locus