Trans-NIH Jak-Stat Initiative - Erythroid: Stat5KO vs WT

Changes in comparison: Test samples for Erythroid: Stat5KO vs WT

Erythropoietic Ter119+ cells from mouse fetal liver cells from Stat5-KO and WT mice.. This used mAdb test: EG1-test-1-FC.

Erythroid: EG001
(T1-)  Stat5KO vs WT --- fold changes < 2X and p-Value<0.05.

This mAdb-derived analysis report compares two groups of samples (A and B) using the paired t-test followed by a fold-change test with the threshold values listed above. The t-test is only done if are at least two samples/condition. It performs fold-change thresholding in either case. The mean A and mean B values are shown as log2 values in the following table as A Mean and B Mean. If there are not enough samples in either condition A or condition B, it only compares the fold-change (mean A/mean B) computed as the difference between the log2 means shown as A-B Mean Difference in this report - see Data Analysis Methods for more discussion. If the t-test is performed, the p-Value is reported as A-B p-Value. Individual sample expression values are reported as the RMA normalized values not using the log2. The tests, thresholding and mAdb Retrieval Report were generated on the mAdb system for the GSP data and subsequently converted to this Web page.

Clicking on the table entries for Gene, Well ID, and Feature ID will go to the GeneCard, mAdb Feature Report, and Affymetrix probe database Web page for that entry. The genes are sorted by A-B Mean Difference with:
   (A) Samples[Stat5KO]: EG001-01, EG001-02, EG001-03
   (B) Samples[WT]: EG001-04, EG001-05, EG001-06.

mAdb Microarray Retrieval Report - Test Samples

Preface to table

Row                  
Row Gene A-B Mean Difference A Mean (Stat5KO) B Mean (WT) A-B p-Value Well ID Feature ID Description Gene Ontology Terms
1 Rsad2 -1.00541 11.49063 12.49605 0.028431841 1337925 1436058_at radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.
2 Rfk -1.01706 10.22975 11.24681 0.013241846 1327556 1415737_at riboflavin kinase (Rfk), mRNA.
3 4632432E15Rik -1.03215 4.80835 5.84050 0.0042505687 1353617 1432885_at RIKEN cDNA 4632432E15 gene  
4 Rfk -1.03490 10.06125 11.09615 0.020805506 1327927 1416230_at riboflavin kinase (Rfk), mRNA.
5 Socs3 -1.03648 7.14218 8.17866 0.004395647 1328194 1416576_at suppressor of cytokine signaling 3 (Socs3), mRNA.
6 Rsad2 -1.04647 9.58681 10.63328 0.041430984 1331607 1421009_at radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.
7   -1.05571 6.81684 7.87255 0.0066383013 1356168 1437087_at Transcribed locus  
8 Trp53bp1 -1.06538 9.29707 10.36245 0.0090267392 1335793 1426957_at transformation related protein 53 binding protein 1 (Trp53bp1), mRNA.
9 Dnaja4 -1.06573 9.86453 10.93026 0.00033938429 1329833 1418591_at DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA.
10 Ucp2 -1.06715 9.05346 10.12061 0.017052203 1361995 1444566_at Uncoupling protein 2 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:13955 IMAGE:4205625)
11 Atad4 -1.07729 6.28994 7.36723 0.01279511 1354336 1433870_at ATPase family, AAA domain containing 4 (Atad4), mRNA.  
12 Rragd -1.09951 5.67937 6.77888 0.014578944 1354873 1434909_at Ras-related GTP binding D (Rragd), mRNA.
13 Ctsf -1.10155 8.30660 9.40815 0.015032786 1340886 1451019_at cathepsin F (Ctsf), mRNA.
14 Socs2 -1.10422 4.22756 5.33178 0.044046052 1343687 1418507_s_at Suppressor of cytokine signaling 2 (Socs2), mRNA
15   -1.12764 7.51998 8.64762 0.010980214 1367299 1456204_at Transcribed locus, strongly similar to NP_001118239.1 hypothetical protein LOC440957 [Homo sapiens]  
16 Fgg -1.13757 9.46173 10.59929 0.049718915 1327771 1416025_at fibrinogen gamma chain (Fgg), mRNA.
17 Spata13 -1.17415 8.29268 9.46683 0.0017270212 1342264 1454656_at Spermatogenesis associated 13, mRNA (cDNA clone MGC:170080 IMAGE:8861475)
18 Ghr -1.18131 6.26565 7.44696 0.023284454 1348960 1451501_a_at growth hormone receptor (Ghr), transcript variant 3, mRNA.
19 Dnaja4 -1.20399 8.64099 9.84498 0.0018253591 1329834 1418592_at DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA.
20 Rfk -1.20996 10.05413 11.26410 0.012327788 1327926 1416229_at riboflavin kinase (Rfk), mRNA.
21 Clcn2 -1.22520 4.41119 5.63639 0.013266759 1339609 1449248_at chloride channel 2 (Clcn2), mRNA.
22 Spata13 -1.22913 7.46344 8.69257 0.018606018 1356572 1437865_at spermatogenesis associated 13 (Spata13), mRNA.
23 Dnaja4 -1.25760 9.04815 10.30575 0.0026042864 1337468 1434196_at DnaJ (Hsp40) homolog, subfamily A, member 4 (Dnaja4), mRNA.
24 Odc1 -1.25898 11.04641 12.30539 0.0020210188 1346063 1427364_a_at ornithine decarboxylase, structural 1 (Odc1), mRNA.
25 Cd36 -1.29680 5.47789 6.77468 0.0073060718 1340774 1450884_at CD36 antigen, mRNA (cDNA clone MGC:6068 IMAGE:3481681)
26 Gpr150 -1.30245 6.33660 7.63906 0.00096615016 1364787 1447485_at G protein-coupled receptor 150, mRNA (cDNA clone MGC:148214 IMAGE:40107174)
27 Cd82 -1.32889 11.22979 12.55867 0.0033034567 1328061 1416401_at CD82 antigen (Cd82), transcript variant 2, mRNA.
28   -1.33044 4.51723 5.84767 0.025238946 1350770 1428909_at Transcribed locus  
29 Fzd5 -1.39992 7.07836 8.47829 0.0083693082 1366993 1455604_at frizzled homolog 5 (Drosophila) (Fzd5), transcript variant 2, mRNA.
30 Stat5a -1.44942 4.10780 5.55722 0.0062547727 1348627 1450259_a_at signal transducer and activator of transcription 5A (Stat5a), mRNA.
31 Cd36 -1.45049 8.74991 10.20041 0.00050637538 1333195 1423166_at CD36 antigen (Cd36), transcript variant 5, mRNA.
32 Ppm1e -1.53593 3.93365 5.46957 0.0017136379 1354916 1434990_at Protein phosphatase 1E (PP2C domain containing), mRNA (cDNA clone MGC:170530 IMAGE:8861925)
33 Ccrn4l -1.59679 9.03486 10.63165 0.023937466 1345554 1425837_a_at CCR4 carbon catabolite repression 4-like (S. cerevisiae) (Ccrn4l), mRNA. rhythmic process
34 Gvin1 -1.61572 6.38305 7.99877 0.0082674284 1350962 1429184_at GTPase, very large interferon inducible 1 (Gvin1), transcript variant B, mRNA.
35 Stat5b -1.64926 5.26860 6.91787 0.0018573437 1344534 1422103_a_at signal transducer and activator of transcription 5B (Stat5b), mRNA.
36 Ston2 -1.67702 6.31349 7.99051 0.00096699816 1355327 1435657_at stonin 2 (Ston2), mRNA.
37 Trp53bp1 -1.72283 8.69096 10.41380 0.030032419 1345980 1426956_a_at transformation related protein 53 binding protein 1 (Trp53bp1), mRNA.
38 Cd36 -1.82117 8.36902 10.19019 0.0032191775 1348794 1450883_a_at CD36 antigen (Cd36), transcript variant 5, mRNA.
39   -1.93829 5.09702 7.03531 0.00011176933 1352813 1431742_at Transcribed locus  
40 Tnfrsf21 -2.20578 7.09062 9.29639 0.00013857393 1332863 1422740_at tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA.
41 Tnfrsf21 -2.57734 7.76192 10.33926 0.00076077815 1348752 1450731_s_at tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), mRNA.
42 Socs3 -2.59612 5.38726 7.98338 0.0065395123 1349871 1456212_x_at Suppressor of cytokine signaling 3 (Socs3), mRNA  
43 Socs3 -2.88373 4.68207 7.56579 0.0010702287 1349775 1455899_x_at suppressor of cytokine signaling 3 (Socs3), mRNA.
44 Apol11b -4.20960 3.41062 7.62022 0.00082666764 1371585 1440927_x_at Apolipoprotein L 11b (Apol11b), mRNA  
45 Apol11b -4.64701 3.55236 8.19937 0.0003222647 1368099 1457307_at Apolipoprotein L 11b (Apol11b), mRNA  


This Web page was derived in collaboration with GSP consortium members.

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Revised: Mon Sep 28 13:56:56 EDT 2009